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Caged Glycan-Antibody Conjugates for Tumor-Selective Activation of Lysosome-Targeting Chimeras
Journal of Medicinal Chemistry
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Small-Molecule Activators of PRMT1: Discovery, SAR Analyses, and Proapoptotic Effects in Pancreatic Cancer Cells
Journal of Medicinal Chemistry
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Selective Brain-Penetrant TTBK1 Inhibitors Modulate TDP-43 Pathology and Rescue Cognitive Deficits in a Mouse Model of TDP-43 Proteinopathy
Journal of Medicinal Chemistry
2026-08-09
Fragment-Based Discovery of Potent RNA-Competitive Inhibitors of the DEAH-Box RNA Helicase DHX8
Journal of Medicinal Chemistry
2026-08-09
Design, Synthesis, and Evaluation of Novel Phenoselenazine Derivatives as Potent Modulators of Aβ42 Aggregation
Journal of Medicinal Chemistry
2026-07-29
A Novel Dual-Targeting PROTAC Overcomes Endocrine Resistance by Engaging Orthosteric and Allosteric Sites of Estrogen Receptor α
Journal of Medicinal Chemistry
2026-08-09
Bis(styryl)benzene Probes for Targeting Early-Stage Amyloid-β Aggregates in Alzheimer’s Disease
ACS Chemical Neuroscience
2026-08-08
An updated patent review of dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A) inhibitors (2020–present)
Expert Opinion on Therapeutic Patents
2026-08-01
Modulating Stress Granules via HDAC6 Inhibition: A Promising Strategy against Alzheimer’s Disease
ACS Chemical Neuroscience
2026-07-28
Ferroptosis and NMDA Receptor Activity in Alzheimer's Disease: Implications for Amyloid Pathology and P‐Glycoprotein Regulation
Drug Development Research
2026-08-22
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