Journal of Applied Physiology

Article	Citations
High-glycemic index meal acutely potentiates blood pressure response to static handgrip exercise in healthy humans	130
The effect of increasing work rate amplitudes from a common metabolic baseline on the kinetic response of V̇o2p, blood flow, and muscle deoxygenation	126
Effect of acute heat exposure on the pressor response to a voluntary hypoxic apnea	95
Renal vascular conductance is unrelated to leg vascular conductance or muscle sympathetic nerve activity at rest and during stress in humans	87
Tramadol is a performance-enhancing drug in highly trained cyclists: a randomized controlled trial	73
Respiratory and chest wall mechanics in very preterm infants	67
Biological sex does not independently influence core temperature change and sweating of children exercising in uncompensable heat stress	63
The physiological effects of creatine supplementation in fetal sheep before, during, and after umbilical cord occlusion and global hypoxia	60
Comparison of analysis strategies to assess sex differences in microvascular reperfusion using near-infrared spectroscopy	60
Sex-specific maturation of muscle metabolites carnosine, creatine, and carnitine over puberty: a longitudinal follow-up study	59
GABAA receptor activation modulates the muscle sympathetic nerve activity responses at the onset of static exercise in humans	55
Exercise effects on γ3-AMPK activity, Akt substrate of 160 kDa phosphorylation, and glucose uptake in muscle of normal and insulin-resistant female rats	54
CORP: Gene delivery into murine skeletal muscle using in vivo electroporation	54
Diaphragm muscle function in a mouse model of early-onset spasticity	50
The effect of trunk position and pain location on lumbar extensor muscle recruitment strategies	49
Proximal pulmonary arterial remodeling impairs right ventricular-arterial coupling in postcapillary pulmonary hypertension patients	47
Let’s talk about sex, let’s talk about pulsatility, let’s talk about all the good things and the bad things of MCAv	43
Influence of the fitting window on the O2 uptake kinetics at the onset of moderate intensity exercise	42
Reply to Grassi and Quaresima	37
Commentaries on Viewpoint: Using V̇o2max as a marker of training status in athletes – can we do better?	37
Fragile bones of elite cyclists: to treat or not to treat?	37
To grant you an edge. Part 3. Considerations for writing competitive research career development proposals in the biomedical sciences	37
Corrigendum for Rosenberg et al., volume 130, 2021, p. 1786–1797	36
Small airways vs large airways in asthma: time for a new perspective	36
A small (but interesting) “trans-Atlantic acid-base debate”	35

Structure-function in smokers: when a small airways test really reflects the small airways	35
Peripheral hypercapnic chemosensitivity at rest and progressive exercise intensities in males and females	35
Cognitive performance is lower among individuals with overlap syndrome than in individuals with COPD or obstructive sleep apnea alone: association with carotid artery stiffness	34
Short bouts of hypoxia improve insulin sensitivity in adults with type 2 diabetes	34
Blood pressure in human large cerebral arteries: a feasibility study	34
Ventilation-perfusion inequality in COVID-19 pneumonia	33
Intralaryngeal application of ATP evokes apneic response mainly via acting on P2X3 (P2X2/3) receptors of the superior laryngeal nerve in postnatal rats	33
Muscle stretching induces the mechanoreflex response in human arterial blood pressure	33
Physiological impacts of computed tomography airway dysanapsis, fractal dimension, and branch count in asymptomatic never smokers	33
Icing after eccentric contraction-induced muscle damage perturbs the disappearance of necrotic muscle fibers and phenotypic dynamics of macrophages in mice	33
Integrative approach to understanding force (un)steadiness	31
Why stick with Fourier analysis for force steadiness: a commentary	31
Divergent mechanisms regulate TLR4 expression on peripheral blood mononuclear cells following workload-matched exercise in normoxic and hypoxic environments	30
Reply to Marino	30
Validation of livability environmental limits to heat and humidity	28
Exercise tolerance, fatigue, mental health, and employment status at 5 and 12 months following COVID-19 illness in a physically trained population	27
Eight weeks of eccentric training at long-muscle length increases fascicle length independently of adaptations in passive mechanical properties	27
Sodium bicarbonate ingestion mitigates the heat-induced hyperventilation and reduction in cerebral blood velocity during exercise in the heat	27
Modeling cerebral blood flow and ventilation instability due to CO2	26
Dilatory responsiveness of the internal carotid artery to shear stimulus is constant under different levels of transient hypercapnia	26
Training volume increases or maintenance based on previous volume: the effects on muscular adaptations in trained males	26
Intra- and interday reliability of sympathetic transduction to blood pressure in young, healthy adults	26
Habitual preexercise caffeine supplementation prevents exercise training-induced attenuation of exercising systolic blood pressure and double product	26
Caffeine alters thermoregulatory responses to exercise in the heat only in caffeine-habituated individuals: a double-blind placebo-controlled trial	26
Running in the heat similarly reduces lipid oxidation and peak oxygen consumption in trained runners and inactive individuals	26
An IL-6 promoter variant (−174 G/C) augments IL-6 production and alters skeletal muscle transcription in response to exercise in mice	26
Increased intrapulmonary shunt and alveolar dead space post-COVID-19	25
Measuring short-term changes in specific ventilation using dynamic specific ventilation imaging	25
Metabolic low-frequency oscillation and abbreviated protocol for estimating REE by indirect calorimetry in healthy adults	25
The role of nitric oxide in flow-induced and myogenic responses in 1A, 2A, and 3A branches of the porcine middle cerebral artery	24
Intravenous bolus injection of fentanyl triggers an immediate central and upper airway obstructive apnea via activating vagal sensory afferents	24
The protective effects of 1,3-butanediol acetoacetate diester on decompression sickness in rats	24
Blood flow restriction and stimulated muscle contractions do not improve metabolic or vascular outcomes following glucose ingestion in young, active individuals	24
Test-retest reliability of exercise blood pressure and the workload-indexed systolic blood pressure slope in healthy males and females	23
Dynamic cerebral autoregulation during repeated handgrip exercise: comparisons with spontaneous rest and sit-stand maneuvers	23
Lower dynamic cerebral autoregulation following acute bout of low-volume high-intensity interval exercise in chronic stroke compared to healthy adults	23
Exercise-induced neuroplasticity in autonomic nuclei restores the cardiac vagal tone and baroreflex dysfunction in aged hypertensive rats	23
Androgen receptor markers do not differ between nonresponders and responders to resistance training-induced muscle hypertrophy	23
“When does it end?” Continuing to align career goals and work-life balance after graduate training	22
The effect of exercise intensity and cardiorespiratory fitness on the kinetic response of middle cerebral artery blood velocity during exercise in healthy adults	22
Neuroplastic alterations in common synaptic inputs and synergistic motor unit clusters controlling the vastii muscles of individuals with ACL reconstruction	22
Sexually dimorphic hepatic mitochondrial adaptations to exercise: a mini-review	22
Effect of condensed heat acclimation on thermophysiological adaptations, hypoxic cross-tolerance, exercise performance, and deacclimation	22
An interventional sheep model of severe aortic valve stenosis hemodynamics for the evaluation of alterations in coronary physiology and microvascular function	21
A tribute to Charles M. “Tip” Tipton (1927–2021)	21
Maternal electronic cigarette use during pregnancy affects long-term arterial function in offspring	21
Last Word on Viewpoint: Acid-base buffering whether quantified as [H+] vs. Pco2 or [H+] vs. strong ion difference is both intuitive and consistent—the role	21
Effects of exercise-induced metabolic and mechanical loading on skeletal muscle mitochondrial function in male rats	21
Biomechanics of human locomotion in the wind	20
Females display relatively preserved muscle quality compared with males during the onset and early stages of C26-induced cancer cachexia	20

Assessing the calculation of conductive and acinar ventilatory heterogeneity indices Scond and Sacin from multiple-breath washout data	20
Acute interleukin-6 modulates key enzymes involved in prefrontal cortex and hippocampal amyloid precursor protein processing	20
Hand and distal joint tremor are most coherent with the activity of elbow flexors and wrist extensors in persons with essential tremor	20
Exogenous ketosis increases circulating dopamine concentration and maintains mental alertness in ultra-endurance exercise	20
Reply to Ewell and Abbotts	19
Eccentric contraction increases hydrogen peroxide levels and alters gene expression through Nox2 in skeletal muscle of male mice	19
Technological advances in sport are an evolving line	19
Irritant-evoked reflex tachyarrhythmia in spontaneously hypertensive rats is reduced by inhalation of TRPM8 agonists l-menthol and WS-12	19
Functional optical coherence tomography at altitude: retinal microvascular perfusion and retinal thickness at 3,800 meters	19
Last Word on Viewpoint: Technological advances in elite sport: Where does one draw the line?	19
Age alters the thermoregulatory responses to extreme heat exposure with accompanying activities of daily living	19
Effects of acetazolamide on pulmonary artery pressure and prevention of high-altitude pulmonary edema after rapid active ascent to 4,559 m	19
Role of lung lobar sliding on parenchymal distortion during breathing	19
Inhibition of muscle sympathetic nerve activity in premenopausal women: responses to sudden sensory stimuli predict responses to mental stress	18
Corrigendum for Luu et al., volume 133, 2022, p. 1192–1201	18
Reply to Nuzzo and Deaner: “Investigator bias” is a potent influence on the underrepresentation of women research participants in biomedical research	18
Submaximal isometric fatiguing exercise of the elbow flexors has no age-related effect on GABAB-mediated inhibition	18
Reply to Drs. Wostyn and Nedergaard	18
Elevated muscle pain induced by a hypertonic saline injection reduces power output independent of physiological changes during fixed perceived effort cycling	18
Chemoradiation to the submental muscles alters hyoid movement during swallowing in a rat model	18
Cortical microglia dynamics are conserved during voluntary wheel running	18
Expanding the framework of proprioception: a comment on Héroux et al.	18
Effects of sex and menstrual cycle phase on celiac artery blood flow during dynamic moderate-intensity leg exercise in young individuals	18
Skeletal muscle adaptations following eccentric contractions are not mediated by keratin 18	17
Effect of conditioning and physiological hyperthermia on canine skeletal muscle mitochondrial oxygen consumption	17
Ansa cervicalis stimulation increases pharyngeal patency in patients with obstructive sleep apnea	17
Altered IGF-I activity and accelerated bone elongation in growth plates precede excess weight gain in a mouse model of juvenile obesity	17
Effects of exercise training with weight loss on skeletal muscle expression of angiogenic factors in overweight and obese older men	17
Consider iron status when making sex comparisons in human physiology	17
The effects of 6 wk of resistance training on the gut microbiome and cardiometabolic health in young adults with overweight and obesity	17
Regional heterogeneity of cerebral blood flow immediately after the onset of ventricular pacing in anesthetized rats	17
Influence of menstrual cycle and oral contraceptive phases on strength performance, neuromuscular fatigue, and perceived exertion	17
Reduced power output in self-paced exercise in the heat is due to thermal and cardiovascular strain but improvements are not?	17
Oxidative stress contributes to reductions in microvascular endothelial- and nitric oxide-dependent dilation in women with a history of gestational diabetes	16
Four hours of normobaric hypoxia reduces Achilles tendon reflex inhibition	16
Attentional focus differentially modulates the corticospinal and intracortical excitability during dynamic and static exercise	16
The Tour de France, but make it recreational: possible for mortals	16
Effects of home-based leg heat therapy on walking performance in patients with symptomatic peripheral artery disease: a pilot randomized trial	16
Effects of prosthetic stiffness and added mass on metabolic power and asymmetry in female runners with a leg amputation	16
Impact of inspiratory threshold loading on brain activity and cognitive performances in healthy humans	16
Limits to submaximal and maximal exercise in patients with hypertrophic cardiomyopathy	16
Greater lactate accumulation does not alter peripheral concentrations of key appetite-regulating neuropeptides	16
In asthma positive phase III slopes can result from structural heterogeneity of the bronchial tree	15
Going against the flow: are venous thromboembolism and impaired cerebral drainage critical risks for spaceflight?	15
Using pulmonary gas exchange to estimate shunt and deadspace in lung disease: theoretical approach and practical basis	15
Mechanisms of the effect of oxidative phosphorylation deficiencies on the skeletal muscle bioenergetic system in patients with mitochondrial myopathies	15
Quadriceps fatigue during hypoxic and ischemic knee-extension exercise is similar in males and females	15
Short-term repeated human biopsy sampling contributes to changes in muscle morphology and higher outcome variability	15
Technology revolution or evolution: track spikes and pacing lights in perspective	15
Temporal longitudinal associations of carotid-femoral pulse wave velocity and carotid intima-media thickness with resting heart rate and inflammation in youth	15
Increasing muscle contractility through low-frequency stimulation alters tibial bone geometry and reduces bone strength in mdx and dko dystrophic mice	15
Endothelin-1 receptor blockade does not alter the sympathetic and hemodynamic response to acute intermittent hypoxia in men	15
Effects of combined treatment with blood flow restriction and low-current electrical stimulation on capillary regression in the soleus muscle of diabetic rats	15
Steadiness, smoothness, and regularity: looking beyond force variability to construct a holistic description of force quality	15
Effects of Analgesic Doses of Opioids on Cardiorespiratory Responses and Survival to Hemorrhage and Trauma in Rats	15
Retraction for Chambers et al., Multitissue responses to exercise: a MoTrPAC feasibility study	15
Delayed metabolic disturbances in the myocardium after exertional heat stroke: contrasting effects of exertion and thermal load	15
Ventilatory long-term facilitation at rest increases the feedforward contribution to subsequent exercise ventilatory responses	15
Concerns for rationale for modeling V̇o2 on-kinetics	15
Technological advancements in sports: balancing innovation with the preservation of athlete authenticity	15
Does the reticulospinal tract mediate adaptation to resistance training in humans?	14
Neural adaptations to long-term resistance training: evidence for the confounding effect of muscle size on the interpretation of surface electromyography	14
Last Word on Viewpoint: Rethinking force steadiness: a new perspective—Yank magnitude: a metric of unsteadiness during the constant isometric force task	14
Limiting radial pedal forces greatly reduces maximal power output and efficiency in sprint cycling; an optimal control study	14
Do changes in cerebral blood flow modulate the amplitudes of P300 during cognitive task?	14
Use visual biofeedback during your workout just like any other method	14
Differences in cerebrovascular regulation and ventilatory responses during ramp incremental cycling in children, adolescents, and adults	14
Airway trees in the Anthropocene	14
Commentaries on Viewpoint: Consider iron status when making sex comparisons in human physiology	14
Impact of exercise duration on gastrointestinal function and symptoms	14
Cardiovascular response at maximal exercise at high altitude	14
Ventilatory response of peripheral chemoreceptors to hypercapnia during exercise above the respiratory compensation point	14
Do we desire better work-life balance or are we being pragmatic?	14
A HIF-1 signature dominates the attenuation in the human skeletal muscle transcriptional response to high-intensity interval training	13
A novel nonlinear analysis of blood flow dynamics applied to the human lung	13
Temporal disruption of neuromuscular communication and muscle atrophy following noninvasive ACL injury in rats	13
In vivo assessment of the passive stretching response of the bicompartmental human semitendinosus muscle using shear-wave elastography	13
Clinical characteristics, risk factors, and cardiac manifestations of cancer patients with COVID-19	13
Impact of presymptomatic COVID-19 on vascular and skeletal muscle function: a case study	13
A 3-D virtual human model for simulating heat and cold stress	13

Postexercise urinary alpha-1 acid glycoprotein is not dependent on hypoxia	13
Functional data analysis of the force unsteadiness	13
Modeling individual differences in cardiovascular response to gravitational stress using a sensitivity analysis	13
Similar endothelium-dependent vascular responses to intermittent hypoxia in young and older adults	13
Adaptability to eccentric exercise training is diminished with age in female mice	13
Postprandial superior mesenteric artery blood flow is related to changes in peripheral pulse wave harmonics and heart rate: implications for wearable technology?	13
Time-course recovery of cerebral blood velocity metrics post aerobic exercise: a systematic review	13
Collapsibility of caval vessels and right ventricular afterload: decoupling of stroke volume variation from preload during mechanical ventilation	13
GDF15 associates with, but is not responsible for, exercise-induced increases in corticosterone and indices of lipid utilization in mice	13
Aerobic exercise training reduces cerebrovascular impedance in older adults: a 1-year randomized controlled trial	13
The impact of elevated body core temperature on critical power as determined by a 3-min all-out test	13
Prenatal fluoxetine has long-lasting, differential effects on respiratory control in male and female rats	13
Positive expiratory pressure: a potential therapy to mitigate acute bronchoconstriction in the asthma of obesity	13
Skeletal muscle-specific calpastatin overexpression mitigates muscle weakness in aging and extends life span	13
Training volume and total energy expenditure of an Olympic and Ironman world champion: approaching the upper limits of human capabilities	13
Case Studies in Physiology: Physiological and clinical effects of temporary diaphragm pacing in two patients with ventilator-induced diaphragm dysfunction	13
Increased corticospinal inhibition following brief maximal and submaximal contractions in humans	12
Pain-induced changes in motor unit discharge depend on recruitment threshold and contraction speed	12
Slight power output manipulations around the maximal lactate steady state have a similar impact on fatigue in females and males	12
In vivo intracellular Ca2+ profiles after eccentric rat muscle contractions: addressing the mechanistic bases for repeated bout protection	12
Arterial load and right ventricular-vascular coupling in pulmonary hypertension	12
Deletion of muscle Igf1 exacerbates disuse atrophy weakness in mice	12
AltitudeOmics: effects of 16 days acclimatization to hypobaric hypoxia on muscle oxygen extraction during incremental exercise	12
Neuromechanical adaptations of foot function when hopping on a damped surface	12
The first and second phases of the muscle compound action potential in the thumb are differently affected by electrical stimulation trains	12
Improving glycemic control via heat therapy in older adults at risk for Alzheimer’s disease (FIGHT-AD): a pilot study	12
Small airways dysfunction is associated with increased exacerbations in patients with asthma	12
Passive heat therapy: a promising preventive measure for people at risk of adverse health outcomes during heat extremes	12
Blood flow restriction training activates the muscle metaboreflex during low-intensity sustained exercise	12
Evidence on sex differences in sports performance	12
Associations of cardiorespiratory fitness with cerebral cortical thickness and gray matter volume across the adult lifespan	12
Clinical and physiological effects of high-intensity aerobic training on metabolic syndrome: understanding the individual exercise response variability	12
Last Word on Viewpoint: Revisiting the effects of the reciprocal function between alveolar ventilation and CO2 partial pressure (PACO2) on PACO2 homeostasis at rest and in exercise	11
Case Studies in Physiology: Adaptation of load-bearing tendons during pregnancy	11
Augmented sympathoexcitation slows postexercise heart rate recovery	11
Hindlimb immobilization induces insulin resistance and elevates mitochondrial ROS production in the hippocampus of female rats	11
Acid-base buffer: H+ load or the supplement rush?	11
Acute overventilation does not cause lung damage in moderately hemorrhaged swine	11
Corrigendum for Schwartz et al., volume 135, 2023, p. 1236–1242	11
Research trainees: Are we aiming for leaders or followers?	11
Controversial technological advancements in sports	11
Eight weeks of inorganic nitrate/nitrite supplementation improves aerobic exercise capacity and the gas exchange threshold in patients with type 2 diabetes	11
Effect of portable noninvasive ventilation on thoracoabdominal volumes in recovery from intermittent exercise in patients with COPD	11
Acute exercise-induced changes in cardiac function relates to right ventricular remodeling following 12-wk hypoxic exercise training	11
Differences in respiratory oscillometry measurements using mouthpiece, mouth, and nasal mask in healthy adults	11
Albumin, oral contraceptives, and venous thromboembolism risk in astronauts	11
Estimation of cardiac potential energy utilizing the pressure-volume area	11
Physiologically variable ventilation prevents lung function deterioration in a model of pulmonary fibrosis	11
CORP: quantification of human skeletal muscle carnosine concentration by proton magnetic resonance spectroscopy	11
Albumin is an important factor in the control of serum free fatty acid flux in both male and female mice	11
Last Word on Viewpoint: Stewart’s approach to quantitative acid-base physiology should replace traditional bicarbonate-centered models	11
Kinetic energy of left ventricular blood flow across heart failure phenotypes and in subclinical diastolic dysfunction	11
Sex differences in biomarkers of end-organ damage following exertional heat stroke in humans	11
Effect of exercise modalities on postexercise hypotension in pre- and postmenopausal women: a systematic review and meta-analysis	11
Reply to Krbec and Duška	11
Corrigendum for Zamir et al., Volume 130, 2021, p. 457–465	11
The acute effect of exercise intensity on peripheral and cerebral vascular function in healthy adults	11
Time-course of V̇o2 kinetics responses during moderate-intensity exercise subsequent to HIIT versus moderate-intensity continuous training in type 2 diabetes	11
Acute preexercise supplementation of combined carnosine and anserine enhances initial maximal power of Wingate tests in humans	11
Women and men report unequal interest in participating in exercise research	11
Type 2 diabetes exacerbates changes in blood pressure-independent arterial stiffness: cross-sectional and longitudinal evidence from the SUMMIT study	10
Persistent physiological benefits from doping? Ethical implications for sports integrity	10
The excessive presence of technology in sports: Are we overvaluing its capabilities?	10
Braving the new world	10
Aging is associated with enhanced central but impaired peripheral arms of the sympathetic baroreflex arc	10
Tongue muscle contractile, fatigue, and fiber type properties in rats	10
Low noncarbonic buffer power amplifies acute respiratory acid-base disorders in patients with sepsis: an in vitro study	10
Asymmetrical nasal high flow ventilation improves clearance of CO2 from the anatomical dead space and increases positive airway pressure	10
Career planning in academia: embracing flexibility, failure, and personal growth	10
Within- and between-day reliability and repeatability of neuromuscular function assessment in females and males	10
Motor cortex plasticity is greater in endurance-trained cyclists following acute exercise	10
Multitissue responses to exercise: a MoTrPAC feasibility study	10
Technological advances in elite running sport concerning advanced footwear technology: yes, but individual preconditions must be considered	10
Increased spinal adenosine impairs phrenic long-term facilitation in aging rats	10
Association between cardiorespiratory fitness and cerebrovascular reactivity to a breath-hold stimulus in older adults: influence of aerobic exercise training	10
Mechanical unloading of 3D-engineered muscle leads to muscle atrophy by suppressing protein synthesis	10
Frequency-dependent coexistence of muscle fatigue and potentiation assessed by concentric isotonic contractions in human plantar flexors	10
Brain insulin resistance and cognitive function: influence of exercise	10
Airway tree caliber heterogeneity and airflow obstruction among older adults	10
Reduced Achilles tendon stiffness in aging associates with higher metabolic cost of walking	10
Work, life, and exercise: the interconnected pathways to health and productivity	10
To grant you an edge: Part 1. General strategies for writing competitive biomedical research proposals	10
The influence of longitudinal muscle fascicle growth on mechanical function	10
Different ramp-incremental slopes elicit similar V̇o2max and fatigability profiles in females and males despite differences in peak power output	10
The correlation between quadriceps muscle strength and endurance and exercise performance in patients with COPD	10
Shear stress induced by acute heat exposure is not obligatory to protect against endothelial ischemia-reperfusion injury in humans	10
How to train your graduate students to (want to) win you awards	10
Lactate as a myokine and exerkine: drivers and signals of physiology and metabolism	10
Secondary denervation is a chronic pathophysiologic sequela of volumetric muscle loss	9
Understanding exercise (in)tolerance in sickle cell disease: impacts of hemolysis and exercise training on skeletal muscle oxygen delivery	9
Respiratory muscle strength pre- and post-maximal apneas in a world champion breath-hold diver	9
Regional lung volume changes with noninvasive positive pressure ventilation in healthy adults	9
Testosterone undecanoate administration prevents declines in fat-free mass but not physical performance during simulated multi-stressor military operations	9
Partitioning the work of breathing during running and cycling using optoelectronic plethysmography	9
Two weeks of high-intensity interval training increases skeletal muscle mitochondrial respiration via complex-specific remodeling in sedentary humans	9