Journal of Applied Physiology

Article	Citations
Effect of acute heat exposure on the pressor response to a voluntary hypoxic apnea	158
High-glycemic index meal acutely potentiates blood pressure response to static handgrip exercise in healthy humans	148
Tramadol is a performance-enhancing drug in highly trained cyclists: a randomized controlled trial	121
A small (but interesting) “trans-Atlantic acid-base debate”	120
Structure-function in smokers: when a small airways test really reflects the small airways	64
Biological sex does not independently influence core temperature change and sweating of children exercising in uncompensable heat stress	62
Attenuated cyclooxygenase-mediated vasodilation in cutaneous microvasculature with no difference in platelet aggregation in women with endometriosis	62
Low-energy cooling strategies modulate biomarkers of kidney injury risk in older adults exposed to very hot and dry heat	62
The effect of trunk position and pain location on lumbar extensor muscle recruitment strategies	61
Short bouts of hypoxia improve insulin sensitivity in adults with type 2 diabetes	56
Respiratory and chest wall mechanics in very preterm infants	49
The effect of increasing work rate amplitudes from a common metabolic baseline on the kinetic response of V̇o2p, blood flow, and muscle deoxygenation	49
Muscle stretching induces the mechanoreflex response in human arterial blood pressure	47
Renal vascular conductance is unrelated to leg vascular conductance or muscle sympathetic nerve activity at rest and during stress in humans	46
Effects of glucose ingestion on blood flow in the small intestine and exercising limbs during endurance exercise	43
Comparison of analysis strategies to assess sex differences in microvascular reperfusion using near-infrared spectroscopy	42
Physiological impacts of computed tomography airway dysanapsis, fractal dimension, and branch count in asymptomatic never smokers	39
Cross-education of unilateral resistance training as a strategy to mitigate immobilization-induced neuromuscular decline: a systematic review and meta-analysis	38
A physics-informed deep learning framework for estimating muscle activation patterns following Achilles tendon repair	34
Dose and time-dependent physiological effects of fentanyl in adult goats	33
Peripheral hypercapnic chemosensitivity at rest and progressive exercise intensities in males and females	33
Physiological markers in females and males after multiple bouts of caloric deprivation during arduous military training	33
Are We Addressing Study Limitations the Right Way? A Conceptual Framework to Distinguish Design Constraints from Methodological Shortcomings	33
Big bones mean big muscles: an MRI-based dataset of muscle-bone-body size relationships across 70 human muscles of the upper limb, trunk, and lower limb	32
Blood pressure in human large cerebral arteries: a feasibility study	32

Anthracycline chemotherapy does not increase arterial stiffness or carotid intima-media thickness in young adult survivors of hematological malignancies	31
Integrative approach to understanding force (un)steadiness	31
Why stick with Fourier analysis for force steadiness: a commentary	31
“When does it end?” Continuing to align career goals and work-life balance after graduate training	29
Divergent mechanisms regulate TLR4 expression on peripheral blood mononuclear cells following workload-matched exercise in normoxic and hypoxic environments	29
Intra- and interday reliability of sympathetic transduction to blood pressure in young, healthy adults	28
Dynamic cerebral autoregulation during repeated handgrip exercise: comparisons with spontaneous rest and sit-stand maneuvers	28
Peripheral chemoreceptors, plant gain, and CO 2 stores as drivers of resting ventilatory control in idiopathic hyperventilation: a prospective case-c	27
The role of nitric oxide in flow-induced and myogenic responses in 1A, 2A, and 3A branches of the porcine middle cerebral artery	27
Androgen receptor markers do not differ between nonresponders and responders to resistance training-induced muscle hypertrophy	27
One force: limited sex differences in retrospective assessment of physiological and psychological attributes of elite warfighters	27
Sexually dimorphic hepatic mitochondrial adaptations to exercise: a mini-review	26
Motor unit discharge properties of the vastii muscles and their modulation with contraction level depend on the knee-joint angle	26
Increased intrapulmonary shunt and alveolar dead space post-COVID-19	26
Exercise-induced neuroplasticity in autonomic nuclei restores the cardiac vagal tone and baroreflex dysfunction in aged hypertensive rats	26
Intravenous bolus injection of fentanyl triggers an immediate central and upper airway obstructive apnea via activating vagal sensory afferents	26
Test-retest reliability of exercise blood pressure and the workload-indexed systolic blood pressure slope in healthy males and females	26
Hypohydration augments the acute increase in urinary biomarkers of kidney injury following the 100-mile Western States Endurance Run	25
Lower dynamic cerebral autoregulation following acute bout of low-volume high-intensity interval exercise in chronic stroke compared to healthy adults	25
Exercise tolerance, fatigue, mental health, and employment status at 5 and 12 months following COVID-19 illness in a physically trained population	25
Neuroplastic alterations in common synaptic inputs and synergistic motor unit clusters controlling the vastii muscles of individuals with ACL reconstruction	25
Effect of condensed heat acclimation on thermophysiological adaptations, hypoxic cross-tolerance, exercise performance, and deacclimation	24
Validation of livability environmental limits to heat and humidity	24
Running in the heat similarly reduces lipid oxidation and peak oxygen consumption in trained runners and inactive individuals	24
Eight weeks of eccentric training at long-muscle length increases fascicle length independently of adaptations in passive mechanical properties	24
Habitual preexercise caffeine supplementation prevents exercise training-induced attenuation of exercising systolic blood pressure and double product	24
An IL-6 promoter variant (−174 G/C) augments IL-6 production and alters skeletal muscle transcription in response to exercise in mice	23
Reply to Horn and Poole	23
Beyond hypothermia: mechanisms of death, rescue, and prevention in cold water immersion - a narrative review	23
Lower diastolic velocity in the internal carotid artery mediates lower cerebral blood flow with age	23
Pre- and postcapillary exercise contributions to pulmonary hypertension in adults > 45 yr	23
Dilatory responsiveness of the internal carotid artery to shear stimulus is constant under different levels of transient hypercapnia	23
Inhibition of muscle sympathetic nerve activity in premenopausal women: responses to sudden sensory stimuli predict responses to mental stress	22
Effects of sex and menstrual cycle phase on celiac artery blood flow during dynamic moderate-intensity leg exercise in young individuals	22
Chemoradiation to the submental muscles alters hyoid movement during swallowing in a rat model	22
Cortical microglia dynamics are conserved during voluntary wheel running	22
Training volume increases or maintenance based on previous volume: the effects on muscular adaptations in trained males	22
Effects of exercise-induced metabolic and mechanical loading on skeletal muscle mitochondrial function in male rats	22
Elevated muscle pain induced by a hypertonic saline injection reduces power output independent of physiological changes during fixed perceived effort cycling	21
Exogenous ketosis increases circulating dopamine concentration and maintains mental alertness in ultra-endurance exercise	21
Assessing the calculation of conductive and acinar ventilatory heterogeneity indices Scond and Sacin from multiple-breath washout data	21
The neuromechanical delay of the vastii muscles lengthens during a voluntary isometric contraction to exhaustion	21
Role of lung lobar sliding on parenchymal distortion during breathing	21
Maternal electronic cigarette use during pregnancy affects long-term arterial function in offspring	21
Functional optical coherence tomography at altitude: retinal microvascular perfusion and retinal thickness at 3,800 meters	21
Regional heterogeneity of cerebral blood flow immediately after the onset of ventricular pacing in anesthetized rats	21
Case study: dose-dependent internal jugular vein response to lower body negative pressure in microgravity quantified by the flow directionality index	21
Expanding the framework of proprioception: a comment on Héroux et al.	20
Last Word on Viewpoint: Acid-base buffering whether quantified as [H+] vs. Pco2 or [H+] vs. strong ion difference is both intuitive and consistent—the role	20
An interventional sheep model of severe aortic valve stenosis hemodynamics for the evaluation of alterations in coronary physiology and microvascular function	20

Reply to Drs. Wostyn and Nedergaard	20
Older adults produce joint moments less economically than young adults	20
Technological advances in sport are an evolving line	20
Last Word on Viewpoint: Technological advances in elite sport: Where does one draw the line?	20
Changes in pulmonary function and airway mechanics with increased serum osmolality	19
Acute interleukin-6 modulates key enzymes involved in prefrontal cortex and hippocampal amyloid precursor protein processing	19
Irritant-evoked reflex tachyarrhythmia in spontaneously hypertensive rats is reduced by inhalation of TRPM8 agonists l-menthol and WS-12	19
Hand and distal joint tremor are most coherent with the activity of elbow flexors and wrist extensors in persons with essential tremor	19
Skeletal muscle adaptations following eccentric contractions are not mediated by keratin 18	19
The effects of 6 wk of resistance training on the gut microbiome and cardiometabolic health in young adults with overweight and obesity	19
Corrigendum for Luu et al., volume 133, 2022, p. 1192–1201	19
Females display relatively preserved muscle quality compared with males during the onset and early stages of C26-induced cancer cachexia	19
Eccentric contraction increases hydrogen peroxide levels and alters gene expression through Nox2 in skeletal muscle of male mice	18
Biomechanics of human locomotion in the wind	18
Age alters the thermoregulatory responses to extreme heat exposure with accompanying activities of daily living	18
Influence of menstrual cycle and oral contraceptive phases on strength performance, neuromuscular fatigue, and perceived exertion	18
Heat stress impairs exogenous carbohydrate oxidation during prolonged running when maintaining euhydration	18
The effects of high altitude (3,800 m) on postactivation potentiation in females and males	18
Reply to Nuzzo and Deaner: “Investigator bias” is a potent influence on the underrepresentation of women research participants in biomedical research	18
Ketone monoester reduces blood glucose, exogenous CHO oxidation, and oxidation efficiency in trained male cyclists when fed 120 g/h of CHO during exercise	18
Can we assess exercise metabolism from skin? Metabolomic profiles in skin dialysate collected during exercise	18
Robustness of hamstring muscle activation strategies following selective hypertrophy induced by Nordic hamstring curl and stiff-leg deadlift exercises	18
How much of HERstory is in the HIStory of the Journal of Applied Physiology?	17
Motor unit adaptations contribute to the repeated bout effect following damaging resistance exercise	17
Technology revolution or evolution: track spikes and pacing lights in perspective	17
Effects of prosthetic stiffness and added mass on metabolic power and asymmetry in female runners with a leg amputation	17
The Tour de France, but make it recreational: possible for mortals	17
Editorial Board	17
Effects of analgesic doses of opioids on cardiorespiratory responses and survival to hemorrhage and trauma in rats	17
Endothelin-1 receptor blockade does not alter the sympathetic and hemodynamic response to acute intermittent hypoxia in men	17
Functional electrical stimulation of the soleus redistributes lower limb joint work distally in young and older adults	17
Retraction for Sun et al., volume 120, 2016, p. 377–390	17
Steadiness, smoothness, and regularity: looking beyond force variability to construct a holistic description of force quality	17
Central command: the navigator in the storm of autonomic reflexes during simulated diving	17
Retraction for Chambers et al., Multitissue responses to exercise: a MoTrPAC feasibility study	17
Delayed metabolic disturbances in the myocardium after exertional heat stroke: contrasting effects of exertion and thermal load	17
Effects of riluzole on sevoflurane-induced gasping in adult mice	17
Computational simulations of hyoid bone position and tracheal displacement: effects on upper airway patency and tissue mechanics	17
Concerns for rationale for modeling V̇o2 on-kinetics	17
Technological advancements in sports: balancing innovation with the preservation of athlete authenticity	17
Regional variability in skin water and heat loss during hemodialysis indicates site-specific skin barrier regulation	17
Four hours of normobaric hypoxia reduces Achilles tendon reflex inhibition	17
Do changes in cerebral blood flow modulate the amplitudes of P300 during cognitive task?	16
Short-term repeated human biopsy sampling contributes to changes in muscle morphology and higher outcome variability	16
Quadriceps fatigue during hypoxic and ischemic knee-extension exercise is similar in males and females	16
Dietary nitrate and muscle contractile function in women: effect of menstrual cycle phase	16
Temporal longitudinal associations of carotid-femoral pulse wave velocity and carotid intima-media thickness with resting heart rate and inflammation in youth	16
Increasing muscle contractility through low-frequency stimulation alters tibial bone geometry and reduces bone strength in mdx and dko dystrophic mice	16
Training status augments mechanisms of rapid-onset vasodilation in healthy young adults	16
Modeling cerebrovascular dynamics during transitions in exercise intensity	16
Does the reticulospinal tract mediate adaptation to resistance training in humans?	16
Attentional focus differentially modulates the corticospinal and intracortical excitability during dynamic and static exercise	16
Comparative assessments of the COSMED adaptive mixing chamber versus breath-by-breath methods for oxygen uptake measurements in recreationally active adults	16
Coronary artery calcification in type 1 diabetes after 10-year ketogenic diet	16
The non-nutritive sweetener erythritol adversely affects brain microvascular endothelial cell function	15
Correction for So et al., volume 140, 2026, p. 1614–1624	15
Acute cardiovascular and cerebral blood flow responses to high frequency, low amplitude vibration on the neck	15
Impact of exercise duration on gastrointestinal function and symptoms	15
Sensorimotor function may be fundamentally limited in hypogravity	15
Greater lactate accumulation does not alter peripheral concentrations of key appetite-regulating neuropeptides	15
Complex interplay between disease and aerobic exercise training on vascular function in an exacerbated emphysema rat model	15
Limits to submaximal and maximal exercise in patients with hypertrophic cardiomyopathy	15
Oxidative stress contributes to reductions in microvascular endothelial- and nitric oxide-dependent dilation in women with a history of gestational diabetes	15
Effects of home-based leg heat therapy on walking performance in patients with symptomatic peripheral artery disease: a pilot randomized trial	15
Ventilatory long-term facilitation at rest increases the feedforward contribution to subsequent exercise ventilatory responses	14
Leg vascular function with advancing age in men: the impact of physical activity and endurance exercise training	14
Prenatal fluoxetine has long-lasting, differential effects on respiratory control in male and female rats	14
Do we desire better work-life balance or are we being pragmatic?	14
M 3 aximizing the exercise response in older adults	14
Increased corticospinal inhibition following brief maximal and submaximal contractions in humans	14
Motor unit discharge and torque steadiness are reduced in people with multiple sclerosis when performing voluntary muscle contractions	14
Effect of Albuterol on Compliance and Distensibility of the Trachea and Lungs	14
Adaptability to eccentric exercise training is diminished with age in female mice	14
Functional data analysis of the force unsteadiness	14
Last Word on Viewpoint: Rethinking force steadiness: a new perspective—Yank magnitude: a metric of unsteadiness during the constant isometric force task	14
GDF15 associates with, but is not responsible for, exercise-induced increases in corticosterone and indices of lipid utilization in mice	14
The first and second phases of the muscle compound action potential in the thumb are differently affected by electrical stimulation trains	14
Cardiovascular challenges of aging in a hotter environment: a narrative review	14
Airway trees in the Anthropocene	14
Limiting radial pedal forces greatly reduces maximal power output and efficiency in sprint cycling; an optimal control study	14

Use visual biofeedback during your workout just like any other method	14
Similar endothelium-dependent vascular responses to intermittent hypoxia in young and older adults	14
Cardiovascular response at maximal exercise at high altitude	14
Clinical and physiological effects of high-intensity aerobic training on metabolic syndrome: understanding the individual exercise response variability	13
Tracking the energetics of mechanical ventilation: real-time patient-ventilator interaction	13
Acid-base buffer: H+ load or the supplement rush?	13
Estimation of cardiac potential energy utilizing the pressure-volume area	13
Training volume and total energy expenditure of an Olympic and Ironman world champion: approaching the upper limits of human capabilities	13
In vivo intracellular Ca 2+ profiles after eccentric rat muscle contractions: addressing the mechanistic bases for repeated bout protection	13
Aerobic exercise training reduces cerebrovascular impedance in older adults: a 1-year randomized controlled trial	13
Evidence on sex differences in sports performance	13
Passive heat therapy: a promising preventive measure for people at risk of adverse health outcomes during heat extremes	13
Improving glycemic control via heat therapy in older adults at risk for Alzheimer’s disease (FIGHT-AD): a pilot study	13
Time-course recovery of cerebral blood velocity metrics post aerobic exercise: a systematic review	13
AltitudeOmics: effects of 16 days acclimatization to hypobaric hypoxia on muscle oxygen extraction during incremental exercise	13
An anerobic boost to a sub-4-min mile	13
Reduced sleep irregularity does not impact peripheral vascular function before or following total sleep deprivation	13
The acute effect of exercise intensity on peripheral and cerebral vascular function in healthy adults	13
Ventilatory response of peripheral chemoreceptors to hypercapnia during exercise above the respiratory compensation point	13
Career planning in academia: embracing flexibility, failure, and personal growth	13
Blood flow restriction training activates the muscle metaboreflex during low-intensity sustained exercise	13
Physiological impact of controlled emergency swimming ascents training in professional divers: evidence of subclinical lung stress	13
Human skeletal muscle-specific hypertrophy with exercise training and aging: a comprehensive review	13
Neuromechanical adaptations of foot function when hopping on a damped surface	13
Associations of cardiorespiratory fitness with cerebral cortical thickness and gray matter volume across the adult lifespan	13
A 3-D virtual human model for simulating heat and cold stress	13
Small airways dysfunction is associated with increased exacerbations in patients with asthma	13
Last Word on Viewpoint: Revisiting the effects of the reciprocal function between alveolar ventilation and CO2 partial pressure (PACO2) on PACO2 homeostasis at rest and in exercise	12
Controversial technological advancements in sports	12
Differences in respiratory oscillometry measurements using mouthpiece, mouth, and nasal mask in healthy adults	12
Women and men report unequal interest in participating in exercise research	12
Integrative physiological study of radiation-induced lung injury: effects on cardiac function and kidney integrity	12
Sex differences in biomarkers of end-organ damage following exertional heat stroke in humans	12
Biomedical research in an age of anxiety: four papers for worried minds	12
Research trainees: Are we aiming for leaders or followers?	12
Regional ventilation distribution: effects of lateral posture and airway clearance techniques in healthy and individuals with COPD	12
Norepinephrine stress reactivity links to a lipid-rich coronary fat phenotype in humans: a cross-sectional study	12
Kinetic energy of left ventricular blood flow across heart failure phenotypes and in subclinical diastolic dysfunction	12
Eight weeks of inorganic nitrate/nitrite supplementation improves aerobic exercise capacity and the gas exchange threshold in patients with type 2 diabetes	12
Corrigendum for Schwartz et al., volume 135, 2023, p. 1236–1242	12
Hindlimb immobilization induces insulin resistance and elevates mitochondrial ROS production in the hippocampus of female rats	12
Reply to Krbec and Duška	12
Frequency-dependent coexistence of muscle fatigue and potentiation assessed by concentric isotonic contractions in human plantar flexors	12
Different ramp-incremental slopes elicit similar V̇o2max and fatigability profiles in females and males despite differences in peak power output	12
Augmented sympathoexcitation slows postexercise heart rate recovery	12
Daily use of countermeasures to prevent headward fluid shifts throughout 30 days of strict head-down tilt bed rest	12
Adaptations in common synaptic inputs to spinal motor neurons during grasping versus a less functional hand task	12
Lower maximal skin wettedness in both warm-humid and hot-dry environments with advanced age (PSU HEAT project)	11
Correction for Bouchama et al., volume 138, 2025, p. 964–978	11
Airway tree caliber heterogeneity and airflow obstruction among older adults	11
The excessive presence of technology in sports: Are we overvaluing its capabilities?	11
The effect of exercise hyperpnea on gross efficiency and anaerobic capacity estimates during a 3-min cycle time trial	11
Impaired neurovascular coupling in metabolic syndrome: an fNIRS study	11
Within- and between-day reliability and repeatability of neuromuscular function assessment in females and males	11
Partially countering the physiologic effects of fentanyl with naloxone or D-Cysteine ethyl ester (D-CYSee) in adult goats	11
The sense and control of standing balance in the presence of motor noise	11
Metformin suppresses the mitochondrial and transcriptional response to exercise, revealing a conserved BCL6B-associated angiogenic program	11
Corrigendum for Debenham et al., volume 136, 2024, p. 1468–1477	11
Reply to Bossi and Matta	11
Braving the new world	11
Testosterone undecanoate administration prevents declines in fat-free mass but not physical performance during simulated multi-stressor military operations	11
Brain insulin resistance and cognitive function: influence of exercise	11
How to train your graduate students to (want to) win you awards	11
Increased spinal adenosine impairs phrenic long-term facilitation in aging rats	11
Asymmetrical nasal high flow ventilation improves clearance of CO2 from the anatomical dead space and increases positive airway pressure	11
Effect of exercise modalities on postexercise hypotension in pre- and postmenopausal women: a systematic review and meta-analysis	11
Effects of single- and bilateral limb immersion on systemic and cerebral hemodynamic responses to the cold pressor test	11
Understanding exercise (in)tolerance in sickle cell disease: impacts of hemolysis and exercise training on skeletal muscle oxygen delivery	11
Type 2 diabetes exacerbates changes in blood pressure-independent arterial stiffness: cross-sectional and longitudinal evidence from the SUMMIT study	11
Work, life, and exercise: the interconnected pathways to health and productivity	11
Negative-pressure-assisted ventilation lowers driving pressure and mechanical power in an ARDS model	11
Large increases in resistance training volume do not impair muscle hypertrophy or anabolic-catabolic molecular signaling in trained individuals	11
Lactate as a myokine and exerkine: drivers and signals of physiology and metabolism	11
Albumin is an important factor in the control of serum free fatty acid flux in both male and female mice	11
Aging is associated with enhanced central but impaired peripheral arms of the sympathetic baroreflex arc	11
Multitissue responses to exercise: a MoTrPAC feasibility study	11
Consideration of sex as a biological variable in the context of thermal physiology and biometeorological research	10
Association of physical activity, sedentary time, and sleep with maternal vascular function in women with a history of preeclampsia	10
Muscle metaboreflex activation via postexercise ischemia increases intercostal muscle blood flow index without evidence of local vasoconstriction in humans	10
Heart rate variability during exercise can quantify cardiorespiratory deconditioning in 55- to 65-yr-old men and women exposed to head-down bed rest	10
Pulmonary adaptations to 12 wk of supervised high intensity interval training in COPD: a nonrandomized controlled pilot study	10
Respiratory muscle strength pre- and post-maximal apneas in a world champion breath-hold diver	10
Ankylosing spondylitis and muscle sympathetic nerve activity: a case study	10
Load- and frequency-dependent impairments to isotonic power are greater than isometric torque following concentric-eccentric fatiguing contractions in humans	10
Normal variation in brain volumetrics, CSF dynamics, and ocular structures from magnetic resonance images of healthy participants over two years	10
Improved vascular function and functional capacity following l-citrulline administration in patients with heart failure with preserved ejection fraction: a single-arm, open-label, prospecti	10
Biomarkers of organ stress and injury following the Boston Marathon	10
Regional lung volume changes with noninvasive positive pressure ventilation in healthy adults	10
Comment on “Effects of biological sex and oral contraceptive pill use on cutaneous microvascular endothelial function and nitric oxide-dependent vasodilation in humans”	10
Flaws in the Van Slyke buffer algorithm?	10
Circulating miRNA levels following a 14-wk aerobic exercise intervention during pregnancy: a secondary exploratory analysis of the PEACH RCT	10
Regional dynamic cerebral autoregulation in acute poikilocapnic hypoxia	10
Common synaptic input between motor units from the lateral and medial posterior soleus compartments does not differ from that within each compartment	10
Long-term exposure to moderate cold reduces incidence of reperfusion tachyarrhythmias in rats	10
Lung volume modulation of sternohyoid muscle function: an anesthetized rat model	10