Lancet Rheumatology

Papers
(The TQCC of Lancet Rheumatology is 10. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-03-01 to 2024-03-01.)
ArticleCitations
Interleukin-1 blockade with high-dose anakinra in patients with COVID-19, acute respiratory distress syndrome, and hyperinflammation: a retrospective cohort study754
Tocilizumab in patients with severe COVID-19: a retrospective cohort study683
Immune mechanisms of pulmonary intravascular coagulopathy in COVID-19 pneumonia545
Anakinra for severe forms of COVID-19: a cohort study489
Clinical criteria for COVID-19-associated hyperinflammatory syndrome: a cohort study226
Tocilizumab among patients with COVID-19 in the intensive care unit: a multicentre observational study216
COVID-19 outcomes in patients with inflammatory rheumatic and musculoskeletal diseases treated with rituximab: a cohort study202
COVID-19-associated hyperinflammation and escalation of patient care: a retrospective longitudinal cohort study190
Silencing the cytokine storm: the use of intravenous anakinra in haemophagocytic lymphohistiocytosis or macrophage activation syndrome184
The immunology of COVID-19: is immune modulation an option for treatment?179
Central sensitisation in chronic pain conditions: latest discoveries and their potential for precision medicine173
Humoral and cellular responses to mRNA vaccines against SARS-CoV-2 in patients with a history of CD20 B-cell-depleting therapy (RituxiVac): an investigator-initiated, single-centre, open-label study169
GM-CSF blockade with mavrilimumab in severe COVID-19 pneumonia and systemic hyperinflammation: a single-centre, prospective cohort study163
Rheumatic disease and COVID-19: initial data from the COVID-19 Global Rheumatology Alliance provider registries143
Anti-C5a antibody IFX-1 (vilobelimab) treatment versus best supportive care for patients with severe COVID-19 (PANAMO): an exploratory, open-label, phase 2 randomised controlled trial142
Dapansutrile, an oral selective NLRP3 inflammasome inhibitor, for treatment of gout flares: an open-label, dose-adaptive, proof-of-concept, phase 2a trial128
Interleukin-1 and interleukin-6 inhibition compared with standard management in patients with COVID-19 and hyperinflammation: a cohort study127
The effect of methotrexate and targeted immunosuppression on humoral and cellular immune responses to the COVID-19 vaccine BNT162b2: a cohort study125
COVID-19 vasculitis and novel vasculitis mimics121
Cardiovascular risk in inflammatory arthritis: rheumatoid arthritis and gout116
Antibody development after COVID-19 vaccination in patients with autoimmune diseases in the Netherlands: a substudy of data from two prospective cohort studies116
Effect of anakinra on mortality in patients with COVID-19: a systematic review and patient-level meta-analysis114
Humoral and cellular immune responses to two and three doses of SARS-CoV-2 vaccines in rituximab-treated patients with rheumatoid arthritis: a prospective, cohort study113
Accumulating evidence suggests anti-TNF therapy needs to be given trial priority in COVID-19 treatment112
Risk of hydroxychloroquine alone and in combination with azithromycin in the treatment of rheumatoid arthritis: a multinational, retrospective study105
Safety and efficacy of rituximab in systemic sclerosis (DESIRES): a double-blind, investigator-initiated, randomised, placebo-controlled trial103
COVACTA trial raises questions about tocilizumab's benefit in COVID-19101
Canakinumab in a subgroup of patients with COVID-1998
Global, regional, and national burden of low back pain, 1990–2020, its attributable risk factors, and projections to 2050: a systematic analysis of the Global Burden of Disease Study 202198
COVID-19 in patients with rheumatic disease in Hubei province, China: a multicentre retrospective observational study97
COVID-19 in patients with rheumatic diseases in northern Italy: a single-centre observational and case–control study94
Vaccination against COVID-19: Expectations and concerns of patients with autoimmune and rheumatic diseases92
Long-term use of immunosuppressive medicines and in-hospital COVID-19 outcomes: a retrospective cohort study using data from the National COVID Cohort Collaborative89
Associations between gut microbiota and genetic risk for rheumatoid arthritis in the absence of disease: a cross-sectional study87
Humoral responses after second and third SARS-CoV-2 vaccination in patients with immune-mediated inflammatory disorders on immunosuppressants: a cohort study86
Imperfect storm: is interleukin-33 the Achilles heel of COVID-19?79
Preventing COVID-19-induced pneumonia with anticytokine therapy76
COVID-19 and immune-mediated inflammatory diseases: effect of disease and treatment on COVID-19 outcomes and vaccine responses74
Viral arthritis and COVID-1970
Perspective of patients with autoimmune diseases on COVID-19 vaccination70
Inflammatory biomarkers in COVID-19-associated multisystem inflammatory syndrome in children, Kawasaki disease, and macrophage activation syndrome: a cohort study69
Autoimmune inflammatory rheumatic diseases and COVID-19 outcomes in South Korea: a nationwide cohort study68
Tolerance of COVID-19 vaccination in patients with systemic lupus erythematosus: the international VACOLUP study68
Assessment of the anti-CD40 antibody iscalimab in patients with primary Sjögren's syndrome: a multicentre, randomised, double-blind, placebo-controlled, proof-of-concept study66
Too long to wait: the impact of COVID-19 on elective surgery65
Flare of rheumatoid arthritis after COVID-19 vaccination62
Humoral and cellular immunogenicity to a second dose of COVID-19 vaccine BNT162b2 in people receiving methotrexate or targeted immunosuppression: a longitudinal cohort study61
First flare of ACPA-positive rheumatoid arthritis after SARS-CoV-2 infection60
B-cell depletion with rituximab in the COVID-19 pandemic: where do we stand?59
Tocilizumab in patients with anti-TNF refractory juvenile idiopathic arthritis-associated uveitis (APTITUDE): a multicentre, single-arm, phase 2 trial59
Safety and efficacy of neurostimulation with a miniaturised vagus nerve stimulation device in patients with multidrug-refractory rheumatoid arthritis: a two-stage multicentre, randomised pilot study59
Temporal trends in severe COVID-19 outcomes in patients with rheumatic disease: a cohort study56
Non-steroidal anti-inflammatory drug use and outcomes of COVID-19 in the ISARIC Clinical Characterisation Protocol UK cohort: a matched, prospective cohort study54
Genetic variants mimicking therapeutic inhibition of IL-6 receptor signaling and risk of COVID-1954
Risk of severe COVID-19 outcomes associated with immune-mediated inflammatory diseases and immune-modifying therapies: a nationwide cohort study in the OpenSAFELY platform54
Long-term effect of tocilizumab in patients with giant cell arteritis: open-label extension phase of the Giant Cell Arteritis Actemra (GiACTA) trial52
Safety profile of baricitinib for the treatment of rheumatoid arthritis over a median of 3 years of treatment: an updated integrated safety analysis51
Of mice and men: converging on a common molecular understanding of osteoarthritis51
Disease-associated and patient-specific immune cell signatures in juvenile-onset systemic lupus erythematosus: patient stratification using a machine-learning approach51
Efficacy of guselkumab on axial involvement in patients with active psoriatic arthritis and sacroiliitis: a post-hoc analysis of the phase 3 DISCOVER-1 and DISCOVER-2 studies51
Mavrilimumab in patients with severe COVID-19 pneumonia and systemic hyperinflammation (MASH-COVID): an investigator initiated, multicentre, double-blind, randomised, placebo-controlled trial51
Reactivation of IgA vasculitis after COVID-19 vaccination51
Abatacept treatment for patients with early active primary Sjögren's syndrome: a single-centre, randomised, double-blind, placebo-controlled, phase 3 trial (ASAP-III study)50
Adverse events after first COVID-19 vaccination in patients with autoimmune diseases50
COVID-19 and systemic lupus erythematosus: a case series48
Novel paediatric presentation of COVID-19 with ARDS and cytokine storm syndrome without respiratory symptoms46
Effect of pre-exposure use of hydroxychloroquine on COVID-19 mortality: a population-based cohort study in patients with rheumatoid arthritis or systemic lupus erythematosus using the OpenSAFELY platf45
68Ga-FAPI-04 PET-CT for molecular assessment of fibroblast activation and risk evaluation in systemic sclerosis-associated interstitial lung disease: a single-centre, pilot study44
Symmetric peripheral polyarthritis developed during SARS-CoV-2 infection44
Adult-onset Still's disease after mRNA COVID-19 vaccine43
Leflunomide–hydroxychloroquine combination therapy in patients with primary Sjögren's syndrome (RepurpSS-I): a placebo-controlled, double-blinded, randomised clinical trial43
Anti-SARS-CoV-2 mRNA vaccine in patients with rheumatoid arthritis42
Patients with rheumatic diseases adhere to COVID-19 isolation measures more strictly than the general population40
Anakinra in COVID-19: important considerations for clinical trials38
Burden of osteoarthritis in China, 1990–2017: findings from the Global Burden of Disease Study 201737
Progression of patients with Raynaud's phenomenon to systemic sclerosis: a five-year analysis of the European Scleroderma Trial and Research group multicentre, longitudinal registry study for Very Ear37
Outcomes of COVID-19 in patients with primary systemic vasculitis or polymyalgia rheumatica from the COVID-19 Global Rheumatology Alliance physician registry: a retrospective cohort study37
Global, regional, and national burden of osteoarthritis, 1990–2020 and projections to 2050: a systematic analysis for the Global Burden of Disease Study 202137
Adult-onset Still's disease following COVID-19 vaccination37
First manifestation of adult-onset Still's disease after COVID-1936
Immediate effect of the COVID-19 pandemic on patient health, health-care use, and behaviours: results from an international survey of people with rheumatic diseases35
Cellular and humoral immunity after the third dose of SARS-CoV-2 vaccine in patients treated with rituximab35
Safety and efficacy of metformin in systemic lupus erythematosus: a multicentre, randomised, double-blind, placebo-controlled trial35
Long-term hydroxychloroquine use in patients with rheumatic conditions and development of SARS-CoV-2 infection: a retrospective cohort study35
COVID-19 cytokine storm: targeting the appropriate cytokine34
COVID-19 in children and young people33
Efficacy of anifrolumab across organ domains in patients with moderate-to-severe systemic lupus erythematosus: a post-hoc analysis of pooled data from the TULIP-1 and TULIP-2 trials33
The role of antirheumatics in patients with COVID-1933
Sarilumab in adults hospitalised with moderate-to-severe COVID-19 pneumonia (CORIMUNO-SARI-1): An open-label randomised controlled trial33
Hydroxychloroquine in the prevention of COVID-19 mortality33
Safety and efficacy of abatacept in early diffuse cutaneous systemic sclerosis (ASSET): open-label extension of a phase 2, double-blind randomised trial32
Autoantibodies against interleukin-1 receptor antagonist in multisystem inflammatory syndrome in children: a multicentre, retrospective, cohort study32
Efficacy and tolerability of a third dose of an mRNA anti-SARS-CoV-2 vaccine in patients with rheumatoid arthritis with absent or minimal serological response to two previous doses31
Arthritis after SARS-CoV-2 infection31
Breakthrough SARS-CoV-2 infections with the delta (B.1.617.2) variant in vaccinated patients with immune-mediated inflammatory diseases using immunosuppressants: a substudy of two prospective cohort s31
Tocilizumab for severe COVID-19 pneumonia – Authors' reply31
Sirolimus for treatment of patients with inclusion body myositis: a randomised, double-blind, placebo-controlled, proof-of-concept, phase 2b trial31
Composite of Relevant Endpoints for Sjögren's Syndrome (CRESS): development and validation of a novel outcome measure30
Laboratory trends, hyperinflammation, and clinical outcomes for patients with a systemic rheumatic disease admitted to hospital for COVID-19: a retrospective, comparative cohort study30
Inflammatory myositis after ChAdOx1 vaccination29
Vaccine effectiveness against SARS-CoV-2 infection and severe outcomes among individuals with immune-mediated inflammatory diseases tested between March 1 and Nov 22, 2021, in Ontario, Canada: a popul28
COVID-19 vaccine effectiveness against omicron (B.1.1.529) variant infection and hospitalisation in patients taking immunosuppressive medications: a retrospective cohort study28
Cutaneous vasculitis following COVID-19 vaccination28
Non-invasive vagus nerve stimulation for rheumatoid arthritis: a proof-of-concept study28
Efficacy, patient-reported outcomes, and safety of the anti-granulocyte macrophage colony-stimulating factor antibody otilimab (GSK3196165) in patients with rheumatoid arthritis: a randomised, phase 227
The conundrum of interleukin-6 blockade in COVID-1927
Caution and clarity required in the use of chloroquine for COVID-1927
Do JAK inhibitors affect immune response to COVID-19 vaccination? Data from the MAJIK-SFR Registry27
Efficacy of rituximab in patients with polymyalgia rheumatica: a double-blind, randomised, placebo-controlled, proof-of-concept trial27
COVID-19 vaccine perceptions and uptake: results from the COVID-19 Global Rheumatology Alliance Vaccine Survey27
Methotrexate and TNF inhibitors affect long-term immunogenicity to COVID-19 vaccination in patients with immune-mediated inflammatory disease26
The Asia-Pacific League of Associations for Rheumatology consensus statements on the management of systemic lupus erythematosus26
Excitement around hydroxychloroquine for treating COVID-19 causes challenges for rheumatology26
COVID-19 and systemic sclerosis: clinicopathological implications from Italian nationwide survey study25
Tocilizumab monotherapy after ultra-short glucocorticoid administration in giant cell arteritis: a single-arm, open-label, proof-of-concept study25
Risk of severe COVID-19 outcomes associated with rheumatoid arthritis and phenotypic subgroups: a retrospective, comparative, multicentre cohort study25
Divergent effects of acute versus chronic glucocorticoids in COVID-1924
SARS-CoV-2 outbreak in immune-mediated inflammatory diseases: the Euro-COVIMID multicentre cross-sectional study24
Frequency of biologic switching and the outcomes of switching in children and young people with juvenile idiopathic arthritis: a national cohort study24
Targeting synovial fibroblast proliferation in rheumatoid arthritis (TRAFIC): an open-label, dose-finding, phase 1b trial24
Ruxolitinib in addition to standard of care for the treatment of patients admitted to hospital with COVID-19 (RUXCOVID): a randomised, double-blind, placebo-controlled, phase 3 trial24
Surgical microdiscectomy versus transforaminal epidural steroid injection in patients with sciatica secondary to herniated lumbar disc (NERVES): a phase 3, multicentre, open-label, randomised controll23
Breakthrough SARS-CoV-2 infections and prediction of moderate-to-severe outcomes during rituximab therapy in patients with rheumatic and musculoskeletal diseases in the UK: a single-centre cohort stud23
Rituximab during the COVID-19 pandemic: time to discuss treatment options with patients23
Long-term efficacy and safety of secukinumab in patients with psoriatic arthritis: 5-year (end-of-study) results from the phase 3 FUTURE 2 study23
Effects of a multi-faceted education and support programme on anxiety symptoms among people with systemic sclerosis and anxiety during COVID-19 (SPIN-CHAT): a two-arm parallel, partially nested, rando22
Antibody durability 6 months after two doses of SARS-CoV-2 mRNA vaccines in patients with rheumatic and musculoskeletal disease21
How long does a shoulder replacement last? A systematic review and meta-analysis of case series and national registry reports with more than 10 years of follow-up21
Non-steroidal anti-inflammatory drug use in COVID-1920
Lessons for rituximab therapy in patients with rheumatoid arthritis20
Patient-reported wellbeing and clinical disease measures over time captured by multivariate trajectories of disease activity in individuals with juvenile idiopathic arthritis in the UK: a multicentre 20
Safety and efficacy of rituximab in systemic sclerosis (DESIRES): open-label extension of a double-blind, investigators-initiated, randomised, placebo-controlled trial20
Risk-based stratified primary care for common musculoskeletal pain presentations (STarT MSK): a cluster-randomised, controlled trial20
Serious postoperative complications and reoperation after carpal tunnel decompression surgery in England: a nationwide cohort analysis20
Hybrid immunity versus vaccine-induced immunity against SARS-CoV-2 in patients with autoimmune rheumatic diseases20
Outcomes with and without outpatient SARS-CoV-2 treatment for patients with COVID-19 and systemic autoimmune rheumatic diseases: a retrospective cohort study20
Immunogenicity and safety of two doses of the CoronaVac SARS-CoV-2 vaccine in SARS-CoV-2 seropositive and seronegative patients with autoimmune rheumatic diseases in Brazil: a subgroup analysis of a p20
Gout and the risk of COVID-19 diagnosis and death in the UK Biobank: a population-based study19
Type I interferon, anti-interferon antibodies, and COVID-1919
Mortality and adverse events of special interest with intravenous belimumab for adults with active, autoantibody-positive systemic lupus erythematosus (BASE): a multicentre, double-blind, randomised, 19
Stratified care versus usual care for management of patients presenting with sciatica in primary care (SCOPiC): a randomised controlled trial19
5-year efficacy and safety of secukinumab in patients with ankylosing spondylitis: end-of-study results from the phase 3 MEASURE 2 trial18
Clinical pathways for patients with giant cell arteritis during the COVID-19 pandemic: an international perspective18
Detection of IgM and IgG antibodies against SARS-CoV-2 in patients with autoimmune diseases18
How long do revised and multiply revised knee replacements last? A retrospective observational study of the National Joint Registry18
Safety and efficacy of tofacitinib up to 48 months in patients with active psoriatic arthritis: final analysis of the OPAL Balance long-term extension study18
Physician Global Assessment International Standardisation COnsensus in Systemic Lupus Erythematosus: the PISCOS study17
Evaluation of SARS-CoV-2 IgG antibody reactivity in patients with systemic lupus erythematosus: analysis of a multi-racial and multi-ethnic cohort17
Investigating sex differences in T regulatory cells from cisgender and transgender healthy individuals and patients with autoimmune inflammatory disease: a cross-sectional study17
Current issues in rheumatoid arthritis-associated interstitial lung disease17
Incident systemic rheumatic disease following COVID-1917
Therapeutic implications of ongoing alveolar viral replication in COVID-1917
Withholding methotrexate after vaccination with ChAdOx1 nCov19 in patients with rheumatoid or psoriatic arthritis in India (MIVAC I and II): results of two, parallel, assessor-masked, randomised contr16
Remotely delivered cognitive behavioural and personalised exercise interventions for fatigue severity and impact in inflammatory rheumatic diseases (LIFT): a multicentre, randomised, controlled, open-16
Clinical and molecular associations with outcomes at 2 years after acute knee injury: a longitudinal study in the Knee Injury Cohort at the Kennedy (KICK)16
Safety, tolerability, efficacy, pharmacokinetics, and pharmacodynamics of the oral TYK2 inhibitor PF-06826647 in participants with plaque psoriasis: a phase 1, randomised, double-blind, placebo-contro15
Diagnostic accuracy of vascular ultrasound in patients with suspected giant cell arteritis (EUREKA): a prospective, multicentre, non-interventional, cohort study15
Disease stratification in giant cell arteritis to reduce relapses and prevent long-term vascular damage15
Iloprost for COVID-19-related vasculopathy15
Lupus low disease activity state and remission and risk of mortality in patients with systemic lupus erythematosus: a prospective, multinational, longitudinal cohort study15
Zilucoplan in immune-mediated necrotising myopathy: a phase 2, randomised, double-blind, placebo-controlled, multicentre trial15
Association between serum urate and flares in people with gout and evidence for surrogate status: a secondary analysis of two randomised controlled trials15
Moderators of the effect of therapeutic exercise for knee and hip osteoarthritis: a systematic review and individual participant data meta-analysis15
How long do revised and multiply revised hip replacements last? A retrospective observational study of the National Joint Registry15
MRI of the joint and evaluation of the granulocyte–macrophage colony-stimulating factor–CCL17 axis in patients with rheumatoid arthritis receiving otilimab: a phase 2a randomised mechanistic study15
Patients with gout: an under-recognised group at high risk of COVID-1915
Immunoglobulin, glucocorticoid, or combination therapy for multisystem inflammatory syndrome in children: a propensity-weighted cohort study15
The STAR care pathway for patients with pain at 3 months after total knee replacement: a multicentre, pragmatic, randomised, controlled trial14
Delving beneath the surface of hyperinflammation in COVID-1914
Definition and validation of serum biomarkers for optimal differentiation of hyperferritinaemic cytokine storm conditions in children: a retrospective cohort study14
Utility of repeated antinuclear antibody tests: a retrospective database study14
Systemic sclerosis in the time of COVID-1914
Optimal length and usefulness of temporal artery biopsies in the diagnosis of giant cell arteritis: a 10-year retrospective review of medical records14
Association between biological immunotherapy for psoriasis and time to incident inflammatory arthritis: a retrospective cohort study14
An adult presentation consistent with PIMS-TS14
Rheumatologists rapidly adjust patient care during COVID-19 pandemic14
Making a big impact with small datasets using machine-learning approaches14
Humoral and cellular immune responses to mRNA COVID-19 vaccines in patients with axial spondyloarthritis treated with adalimumab or secukinumab14
Pre-exposure anti-SARS-CoV-2 monoclonal antibodies in severely immunocompromised patients with immune-mediated inflammatory diseases13
Safety and preliminary efficacy of allogeneic bone marrow-derived multipotent mesenchymal stromal cells for systemic sclerosis: a single-centre, open-label, dose-escalation, proof-of-concept, phase 1/13
High-stakes heterogeneity in COVID-1913
The global epidemic of low back pain13
IL-1 and IL-6 inhibition affects the neutralising activity of anti-SARS-CoV-2 antibodies in patients with COVID-1913
Treatment tapering and stopping in patients with rheumatoid arthritis in stable remission (RETRO): a multicentre, randomised, controlled, open-label, phase 3 trial13
Abatacept in IgG4-related disease: a prospective, open-label, single-arm, single-centre, proof-of-concept study13
Glucocorticoid gene signatures in systemic lupus erythematosus and the effects of type I interferon: a cross-sectional and in-vitro study13
Thromboses and COVID-19: reducing inflammation in addition to thromboprophylaxis13
Anakinra for severe forms of COVID-1913
Circulating collagen neo-epitopes and their role in the prediction of fibrosis in patients with systemic sclerosis: a multicentre cohort study13
Randomised controlled trials in systemic sclerosis: patient selection and endpoints for next generation trials12
Rapid distribution of information by SMS-embedded video link to patients during a pandemic12
FDA approval for anifrolumab in patients with lupus12
Global, regional, and national burden of rheumatoid arthritis, 1990–2020, and projections to 2050: a systematic analysis of the Global Burden of Disease Study 202112
Safety and tolerability of mRNA COVID-19 vaccines in people with antiphospholipid antibodies12
Musculoskeletal manifestations of childhood cancer and differential diagnosis with juvenile idiopathic arthritis (ONCOREUM): a multicentre, cross-sectional study12
Clinician-reported outcome measures in lupus trials: a problem worth solving12
Genetic IL-6R variants and therapeutic inhibition of IL-6 receptor signalling in COVID-1912
Antibody kinetics in patients with rheumatic diseases after SARS-CoV-2 mRNA vaccination11
The Lazarus effect of very high-dose intravenous anakinra in severe non-familial CNS-HLH11
Intensity and longevity of SARS-CoV-2 vaccination response in patients with immune-mediated inflammatory disease: a prospective cohort study11
Coronavirus is the trigger, but the immune response is deadly11
Anti-tumour necrosis factor therapy for early-stage Dupuytren's disease (RIDD): a phase 2b, randomised, double-blind, placebo-controlled trial11
COVID-19 vaccine acceptance over time in patients with immune-mediated inflammatory rheumatic diseases11
The multifaceted problem of pulmonary arterial hypertension in systemic sclerosis11
Anti-granulocyte-macrophage colony-stimulating factor antibody otilimab in patients with hand osteoarthritis: a phase 2a randomised trial10
The future of treatment in systemic sclerosis: can we design better trials?10
Acceptability of the COVID-19 vaccine among patients with chronic rheumatic diseases and health-care professionals: a cross-sectional study in 19 Arab countries10
Tofacitinib as monotherapy following methotrexate withdrawal in patients with psoriatic arthritis previously treated with open-label tofacitinib plus methotrexate: a randomised, placebo-controlled sub10
Immunosuppression and SARS-CoV-2 breakthrough infections10
Tolerance-inducing medicines in autoimmunity: rheumatology and beyond10
Safety and efficacy of secukinumab in patients with giant cell arteritis (TitAIN): a randomised, double-blind, placebo-controlled, phase 2 trial10
Four SARS-CoV-2 vaccine doses or hybrid immunity in patients on immunosuppressive therapies: a Norwegian cohort study10
Changing COVID-19 outcomes in patients with rheumatic disease—are we really getting better at this?10
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