OOIR: Observatory of International Research

Papers

(The median citation count of BMC Molecular and Cell Biology is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
Upregulation of CCT3 predicts poor prognosis and promotes cell proliferation via inhibition of ferroptosis and activation of AKT signaling in lung adenocarcinoma	33
LEP O-GlcNAcylation inactivates NF-κB pathway by suppressing LEP protein level and thus mediates cellular senescence and osteogenic differentiation in mouse mesenchymal stem cells	28
Development of an in vitro human alveolar epithelial air-liquid interface model using a small molecule inhibitor cocktail	23
The role of proteoglycan form of DMP1 in cranial repair	23
Simple, low-cost, and well-performing method, the outgrowth technique, for the isolation of cells from nasal polyps	21
Method for determining of cytotoxicity based on the release of fluorescent proteins	20
High levels of follicular fluid testosterone could impair oocyte developmental competency via affecting aryl hydrocarbon receptor pathway in PCOS patients	20
Searching for protein partners of short-chain 3-hydroxyacyl-CoA dehydrogenase (SCHAD) reveals keratin 8 as a novel candidate for interaction in pancreatic β-cells	19
Association between plasma L-carnitine levels and mitochondrial DNA copy number	19
Differential methylation patterns in paternally imprinted gene promoter regions in sperm from hepatitis B virus infected individuals	19
microRNA-338-3p suppresses lipopolysaccharide-induced inflammatory response in HK-2 cells	18
Optimisation of cryopreservation conditions, including storage duration and revival methods, for the viability of human primary cells	17
Correction: Glycogen Synthase Kinase-3 regulates IGFBP-1 gene transcription through the Thymine-rich Insulin Response Element	17
Melatonin reduces lung injury in type 1 diabetic mice by the modulation of autophagy	15
Transcriptome and DNA methylation profiling during the NSN to SN transition in mouse oocytes	15
Mitochondrial HMGCS1 mediates cisplatin resistance in cervical cancer through regulation of mitochondrial transcription	13
Convergent evolution of type I antifreeze proteins from four different progenitors in response to global cooling	13
Designing multi-epitope vaccines against Echinococcus granulosus: an in-silico study using immuno-informatics	13
N-actylcysteine inhibits diethyl phthalate-induced inflammation via JNK and STAT pathway in RAW264.7 macrophages	13
Alcohol exposure induces ferroptosis-dominated programmed cell death in esophageal epithelial cells	12
Neuroprotective effect of ciclopirox olamine in retinal ischemia/reperfusion injury	11
Overexpression of lncRNA HOXA-AS2 promotes the progression of oral squamous cell carcinoma by mediating SNX5 expression	11
Dose-dependent effects of atorvastatin on inflammatory response in endothelial cells: MMP/TIMP balance and in vitro wound closure assay	11
Immune gene expression in salmon keratocytes upon bacterial exposure	11
MicroRNA-145-5p modulates Krüppel-like factor 5 and inhibits cell proliferation, migration, and invasion in nasopharyngeal carcinoma	11

Isolation and characterization of mesenchymal stem cells from nasal polyps and olfactory mucosa: a comparative analysis of proliferation and multi-lineage differentiation capacity	11
The formin FMNL2 plays a role in the response of melanoma cells to substrate stiffness	10
SCAT8/miR-125b-5p axis triggers malignant progression of nasopharyngeal carcinoma through SCARB1	9
Long non-coding RNA SOX2OT in tamoxifen-resistant breast cancer	9
Upregulated dual oxidase 1-induced oxidative stress and caspase-1-dependent pyroptosis reflect the etiologies of heart failure	9
Hik28-dependent and Hik28-independent ABC transporters were revealed by proteome-wide analysis of ΔHik28 under combined stress	9
Chromatin structure in cancer	9
Systematic study of single-cell isolation from musculoskeletal tissues for single-sell sequencing	9
Mutant Fam20c knock-in mice recapitulate both lethal and non-lethal human Raine Syndrome	9
The dual role of Nrf2 in melanoma: a systematic review	8
Hyperoxia exposure upregulates Dvl-1 and activates Wnt/β-catenin signaling pathway in newborn rat lung	7
The proneural transcription factor Atoh1 promotes odontogenic differentiation in human dental pulp stem cells (DPSCs)	7
Angiogenic ability of human endothelial cells was decreased following senescence induction with hydrogen peroxide: possible role of vegfr-2/akt-1 signaling pathway	7
Immunomodulatory effects of TAK-242 on osteogenesis of mesenchymal stem cells in acute inflammatory conditions	7
Sex alters thyroid hormone’s effect on protein O-GlcNAcylation in the aged mouse heart	7
Molecular architecture of mesoderm cells across early to middle stage of human embryo development at single-cell resolution	7
Cell biology of Dictyostelium	7
Role of layilin in regulating mitochondria-mediated apoptosis: a study on B cell lymphoma (BCL)-2 family proteins	7
Ribosomal protein RPL5 regulates colon cancer cell proliferation and migration through MAPK/ERK signaling pathway	7
Chemotactic motion of coronin-null cells with impaired actin turnover	7
In situ proximity ligation assay for analysing spatial interactions between ciliary proteins	7
The DNA demethylation-regulated SFRP2 dictates the progression of endometriosis via activation of the Wnt/β-catenin signaling pathway	7
Knockdown of ELF4 aggravates renal injury in ischemia/reperfusion mice through promotion of pyroptosis, inflammation, oxidative stress, and endoplasmic reticulum stress	7
Effects of growth hormone/estrogen/androgen on COVID-19-type proinflammatory responses in normal human lung epithelial BEAS-2B cells	6
The 3-O sulfation of heparan sulfate proteoglycans contributes to the cellular internalization of tau aggregates	6
OSGIN2 regulates osteogenesis of jawbone BMSCs in osteoporotic rats	6
Methodological approach for allele-specific antibody responses to HEK-293T-based cell lines expressing single MHC class I chain-related gene B antigens	6
Myogenic differentiation of human myoblasts and Mesenchymal stromal cells under GDF11 on Poly-ɛ-caprolactone-collagen I-Polyethylene-nanofibers	6
A nanobody-based degron system for targeted protein knockdown in Dictyostelium discoideum	6
Conserved structural topologies in RNase A-like and trypsin-like serine proteases: a sequence-based folding analysis	6
Mesenchymal stem cells- derived exosomes inhibit the expression of Aquaporin-5 and EGFR in HCT-116 human colorectal carcinoma cell line	5
Splicing isoforms associated with TGFβ-induced myofibroblast activation	5
The role of the TGF-β/LIF signaling pathway mediated by SMADs during the cyst formation of Echinococcus in young children	5
Downregulation of miR-451 in cholangiocarcinoma help the diagnsosi and promotes tumor progression	5
Emodin and aloe-emodin, two potential molecules in regulating cell migration of skin cells through the MAP kinase pathway and affecting Caenorhabditis elegans thermotolerance	5
Assessment of XCI skewing and demonstration of XCI escape region based on single-cell RNA sequencing: comparison between female Grave’s disease and control	5
Mice lacking DIO3 exhibit sex-specific alterations in circadian patterns of corticosterone and gene expression in metabolic tissues	5
Evolutionary relevance of single nucleotide variants within the forebrain exclusive human accelerated enhancer regions	5
Subtype-specific divergent roles of calpain-1 and calpain-2 in basal A triple-negative breast cancer	5
Effects of prey quality through the life cycle of the social amoeba Dictyostelium discoideum	5
EphrinB2 in dental pulp stem cells promotes endothelial cells forming capillary-like cords in a 3D bioprinted hydrogel construct	5
Loss of Dec1 inhibits alcohol-induced hepatic lipid accumulation and circadian rhythm disorder	5
Evaluation of the putative lymphoma-associated point mutation D427H in the STAT3 transcription factor	5
circFTO binding with IGF2BP2 regulates trophoblast cells proliferation, migration, and invasion while mediating m6A modification of CCAR1 mRNA in spontaneous abortion	5
Comparing chemical transfection, electroporation, and lentiviral vector transduction to achieve optimal transfection conditions in the Vero cell line	4
Mineral elements and adiposity-related consequences in adolescents with intellectual disabilities	4
RUNX3 mediates keloid fibroblast proliferation through deacetylation of EZH2 by SIRT1	4
A role for PaxB in regulating blebbing: experimental insights and theoretical perspectives from Dictyostelium discoideum	4
BMP9 maintains the phenotype of HTR-8/Svneo trophoblast cells by activating the SDF1/CXCR4 pathway	3
The Wnt/β-catenin pathway maintains homeostasis of amniocytes in Down syndrome	3

Acetaminophen changes the RNA m6A levels and m6A-related proteins expression in IL-1β-treated chondrocyte cells	3
Prioritization of Trypanosoma brucei editosome protein interactions interfaces at residue resolution through proteome-scale network analysis	3
Correction: The primary cilium dampens proliferative signaling and represses a G2/M transcriptional network in quiescent myoblasts	3
Optimization of seeding density of OP9 cells to improve hematopoietic differentiation efficiency	3
Ciliary p75 neurotrophin receptor (p75NTR) facilitates the enrichment of exogenous amyloid beta (Aβ 1–42) peptide and promotes oxidative stress in human hippocampal astrocytes	3
Effects of irisin on inflammatory and apoptotic markers in the Caco-2 colon cancer cell line	3
Keratin 19 binds and regulates cytoplasmic HNRNPK mRNA targets in triple-negative breast cancer	3
CARD9 contributes to ovarian cancer cell proliferation, cycle arrest, and cisplatin sensitivity	3
In silico prediction, characterization, docking studies and molecular dynamics simulation of human p97 in complex with p37 cofactor	3
RPL11 promotes non-small cell lung cancer cell proliferation by regulating endoplasmic reticulum stress and cell autophagy	3
Canine intestinal organoids as a platform for studying MHC class II expression in epithelial cells	3
IDPsBind: a repository of binding sites for intrinsically disordered proteins complexes with known 3D structures	3
A computational peptide model induces cancer cells’ apoptosis by docking Kringle 5 to GRP78	3
High-fat diet enhances cell proliferation and compromises intestinal permeability in a translational canine intestinal organoid model	3
Comprehensive brain tissue metabolomics and biological network technology to decipher the mechanism of hydrogen-rich water on Radiation-induced cognitive impairment in rats	3
Sumoylation of SAP130 regulates its interaction with FAF1 as well as its protein stability and transcriptional repressor function	3