OOIR: Observatory of International Research

Papers

(The median citation count of BMC Molecular and Cell Biology is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)

Article	Citations
Simple, low-cost, and well-performing method, the outgrowth technique, for the isolation of cells from nasal polyps	56
The role of proteoglycan form of DMP1 in cranial repair	46
Method for determining of cytotoxicity based on the release of fluorescent proteins	33
Upregulation of CCT3 predicts poor prognosis and promotes cell proliferation via inhibition of ferroptosis and activation of AKT signaling in lung adenocarcinoma	22
High levels of follicular fluid testosterone could impair oocyte developmental competency via affecting aryl hydrocarbon receptor pathway in PCOS patients	21
LEP O-GlcNAcylation inactivates NF-κB pathway by suppressing LEP protein level and thus mediates cellular senescence and osteogenic differentiation in mouse mesenchymal stem cells	20
Development of an in vitro human alveolar epithelial air-liquid interface model using a small molecule inhibitor cocktail	19
Comparative transcriptomic analysis reveals gene regulation mediated by caspase activity in a chordate organism	18
Optimization of fuzzy c-means (FCM) clustering in cytology image segmentation using the gray wolf algorithm	18
NanoBRET in C. elegans illuminates functional receptor interactions in real time	16
Searching for protein partners of short-chain 3-hydroxyacyl-CoA dehydrogenase (SCHAD) reveals keratin 8 as a novel candidate for interaction in pancreatic β-cells	16
Differential methylation patterns in paternally imprinted gene promoter regions in sperm from hepatitis B virus infected individuals	14
Association between plasma L-carnitine levels and mitochondrial DNA copy number	14
microRNA-338-3p suppresses lipopolysaccharide-induced inflammatory response in HK-2 cells	14
Correction: Glycogen Synthase Kinase-3 regulates IGFBP-1 gene transcription through the Thymine-rich Insulin Response Element	13
Exportin Crm1 is important for Swi6 nuclear shuttling and MBF transcription activation in Saccharomyces cerevisiae	13
Correction to: A potential implication of UDP-glucuronosyltransferase 2B10 in the detoxification of drugs used in pediatric hematopoietic stem cell transplantation setting: an in silico investigation	13
N-actylcysteine inhibits diethyl phthalate-induced inflammation via JNK and STAT pathway in RAW264.7 macrophages	12
The 3D nuclear conformation of the major histocompatibility complex changes upon cell activation both in porcine and human macrophages	12
Convergent evolution of type I antifreeze proteins from four different progenitors in response to global cooling	12
Optimisation of cryopreservation conditions, including storage duration and revival methods, for the viability of human primary cells	12
Uncarboxylated osteocalcin promotes proliferation and metastasis of MDA-MB-231 cells through TGF-β/SMAD3 signaling pathway	11
Designing multi-epitope vaccines against Echinococcus granulosus: an in-silico study using immuno-informatics	11
Neuroprotective effect of ciclopirox olamine in retinal ischemia/reperfusion injury	11
Melatonin reduces lung injury in type 1 diabetic mice by the modulation of autophagy	11

MicroRNA-145-5p modulates Krüppel-like factor 5 and inhibits cell proliferation, migration, and invasion in nasopharyngeal carcinoma	11
Transcriptome and DNA methylation profiling during the NSN to SN transition in mouse oocytes	11
Intercellular transfer of mitochondrial DNA carrying metastasis-enhancing pathogenic mutations from high- to low-metastatic tumor cells and stromal cells via extracellular vesicles	10
Overexpression of lncRNA HOXA-AS2 promotes the progression of oral squamous cell carcinoma by mediating SNX5 expression	10
SCAT8/miR-125b-5p axis triggers malignant progression of nasopharyngeal carcinoma through SCARB1	10
The formin FMNL2 plays a role in the response of melanoma cells to substrate stiffness	10
Hik28-dependent and Hik28-independent ABC transporters were revealed by proteome-wide analysis of ΔHik28 under combined stress	10
Upregulated dual oxidase 1-induced oxidative stress and caspase-1-dependent pyroptosis reflect the etiologies of heart failure	9
Mutant Fam20c knock-in mice recapitulate both lethal and non-lethal human Raine Syndrome	9
Hyperoxia exposure upregulates Dvl-1 and activates Wnt/β-catenin signaling pathway in newborn rat lung	8
Chromatin structure in cancer	8
Long non-coding RNA SOX2OT in tamoxifen-resistant breast cancer	8
Systematic study of single-cell isolation from musculoskeletal tissues for single-sell sequencing	8
An alternative D. melanogaster 7SK snRNP	8
Sex alters thyroid hormone’s effect on protein O-GlcNAcylation in the aged mouse heart	7
The proneural transcription factor Atoh1 promotes odontogenic differentiation in human dental pulp stem cells (DPSCs)	7
Ribosomal protein RPL5 regulates colon cancer cell proliferation and migration through MAPK/ERK signaling pathway	7
Angiogenic ability of human endothelial cells was decreased following senescence induction with hydrogen peroxide: possible role of vegfr-2/akt-1 signaling pathway	7
The dual role of Nrf2 in melanoma: a systematic review	7
Systemic administration of c-Kit+ cells diminished pulmonary and vascular inflammation in rat model of chronic asthma	7
The absence of the autoimmune regulator gene (AIRE) impairs the three-dimensional structure of medullary thymic epithelial cell spheroids	7
Structural insights into the non-inhibitory mechanism of the anti-EGFR EgB4 nanobody	6
Protein kinase C regulates organic anion transporter 1 through phosphorylating ubiquitin ligase Nedd4–2	6
Role of layilin in regulating mitochondria-mediated apoptosis: a study on B cell lymphoma (BCL)-2 family proteins	6
Knockdown of ELF4 aggravates renal injury in ischemia/reperfusion mice through promotion of pyroptosis, inflammation, oxidative stress, and endoplasmic reticulum stress	6
The DNA demethylation-regulated SFRP2 dictates the progression of endometriosis via activation of the Wnt/β-catenin signaling pathway	6
MAPKAPK5-AS1 drives the progression of hepatocellular carcinoma via regulating miR-429/ZEB1 axis	6
Effects of growth hormone/estrogen/androgen on COVID-19-type proinflammatory responses in normal human lung epithelial BEAS-2B cells	5
Methodological approach for allele-specific antibody responses to HEK-293T-based cell lines expressing single MHC class I chain-related gene B antigens	5
Fyn kinase regulates dopaminergic neuronal apoptosis in animal and cell models of high glucose (HG) treatment	5
The 3-O sulfation of heparan sulfate proteoglycans contributes to the cellular internalization of tau aggregates	5
Conserved structural topologies in RNase A-like and trypsin-like serine proteases: a sequence-based folding analysis	5
An integrative analysis of DNA methylation and transcriptome showed the dysfunction of MAPK pathway was involved in the damage of human chondrocyte induced by T-2 toxin	5
OSGIN2 regulates osteogenesis of jawbone BMSCs in osteoporotic rats	5
Loss of Dec1 inhibits alcohol-induced hepatic lipid accumulation and circadian rhythm disorder	4
Effect of bacterial infection on sperm quality and DNA fragmentation in subfertile men with Leukocytospermia	4
High miRNA-378 expression has high diagnostic values for pulmonary tuberculosis and predicts adverse outcomes	4
Emodin and aloe-emodin, two potential molecules in regulating cell migration of skin cells through the MAP kinase pathway and affecting Caenorhabditis elegans thermotolerance	4
A potential implication of UDP-glucuronosyltransferase 2B10 in the detoxification of drugs used in pediatric hematopoietic stem cell transplantation setting: an in silico investigation	4
A computational model of mutual antagonism in the mechano-signaling network of RhoA and nitric oxide	4
Identification of critical residues of O-antigen-modifying O-acetyltransferase B (OacB) of Shigella flexneri	4
Myogenic differentiation of human myoblasts and Mesenchymal stromal cells under GDF11 on Poly-ɛ-caprolactone-collagen I-Polyethylene-nanofibers	4
Evolutionary relevance of single nucleotide variants within the forebrain exclusive human accelerated enhancer regions	4
Evaluation of the putative lymphoma-associated point mutation D427H in the STAT3 transcription factor	4
Intracellular targeting of Cisd2/Miner1 to the endoplasmic reticulum	4
Mesenchymal stem cells- derived exosomes inhibit the expression of Aquaporin-5 and EGFR in HCT-116 human colorectal carcinoma cell line	4
Comparing chemical transfection, electroporation, and lentiviral vector transduction to achieve optimal transfection conditions in the Vero cell line	4
RUNX3 mediates keloid fibroblast proliferation through deacetylation of EZH2 by SIRT1	4
Systematic identification of non-canonical transcription factor motifs	4
Mice lacking DIO3 exhibit sex-specific alterations in circadian patterns of corticosterone and gene expression in metabolic tissues	4

The role of the TGF-β/LIF signaling pathway mediated by SMADs during the cyst formation of Echinococcus in young children	4
Downregulation of miR-451 in cholangiocarcinoma help the diagnsosi and promotes tumor progression	4
KDM6A mutations promote acute cytoplasmic DNA release, DNA damage response and mitosis defects	4
Assessment of XCI skewing and demonstration of XCI escape region based on single-cell RNA sequencing: comparison between female Grave’s disease and control	4
Influence of mechanical and TGF-β3 stimulation on the tenogenic differentiation of tonsil-derived mesenchymal stem cells	4
circFTO binding with IGF2BP2 regulates trophoblast cells proliferation, migration, and invasion while mediating m6A modification of CCAR1 mRNA in spontaneous abortion	4
RNAP II produces capped 18S and 25S ribosomal RNAs resistant to 5′-monophosphate dependent processive 5′ to 3′ exonuclease in polymerase switched Saccharomyces cerevisiae	3
Sumoylation of SAP130 regulates its interaction with FAF1 as well as its protein stability and transcriptional repressor function	3
A computational peptide model induces cancer cells’ apoptosis by docking Kringle 5 to GRP78	3
Mineral elements and adiposity-related consequences in adolescents with intellectual disabilities	3
RPL11 promotes non-small cell lung cancer cell proliferation by regulating endoplasmic reticulum stress and cell autophagy	3
IDPsBind: a repository of binding sites for intrinsically disordered proteins complexes with known 3D structures	3
Canine intestinal organoids as a platform for studying MHC class II expression in epithelial cells	3
BMP9 maintains the phenotype of HTR-8/Svneo trophoblast cells by activating the SDF1/CXCR4 pathway	3
Optimization of seeding density of OP9 cells to improve hematopoietic differentiation efficiency	3
Retraction Note: Proteomic analysis on N, N′-dinitrosopiperazine-mediated metastasis of nasopharyngeal carcinoma 6-10B cells	3
Keratin 19 binds and regulates cytoplasmic HNRNPK mRNA targets in triple-negative breast cancer	3
Long non-coding RNA TUG1 promotes proliferation and migration in PDGF-BB-stimulated HASMCs by regulating miR-216a-3p/SMURF2 axis	3