Stem Cell Reviews and Reports

Article	Citations
Tissue-resident stem/progenitor cells endowed with broader germ layer specification potential in normal and cancerous tissues	217
Targeting Redundant ROBO1 and SDF-1 Pathways Prevents Adult Hemangioblast Derived-EPC and CEC Activity Effectively Blocking Tumor Neovascularization	125
How Faithful Flt3-Cre Mouse is to Hematopoietic Lineage Tracing?	118
Human Umbilical Cord Mesenchymal Stem Cells for the Treatment of Systemic Lupus Erythematosus via Glucose Metabolism of CD4+T Cells	73
Conventional and Alternative B Lymphopoiesis: Multiple Roads to Immunity	72
Exploring Compositions of Cell-Based Therapies for Diabetic Foot Ulcer Treatment: A Review of Clinical Studies	69
Extracellular Vesicle-Enhanced Stem Cell Therapy in Acute Myocardial Infarction: A Case Report of Cardiac Regeneration from a Bypass Surgery	61
The Role of Viral Infections in Acute Kidney Injury and Mesenchymal Stem Cell-Based Therapy	56
Human Amniotic Mesenchymal Stem Cells Alleviate aGVHD after allo-HSCT by Regulating Interactions between Gut Microbiota and Intestinal Immunity	53
Osteopontin Rejuvenates Senescent Adipose-Derived Stem Cells and Restores their Bone Tissue Regenerative Function	51
Obituary for Prof. Peter J. Quesenberry (1938-2025)	49
Therapeutic Effectiveness of Anticancer Agents Targeting Different Signaling Molecules Involved in Asymmetric Division of Cancer Stem Cell	48
Evaluation of Endothelial Progenitor Cell Characteristics as Clinical Biomarkers for Elderly Patients with Ischaemic Stroke	46
Mesenchymal Stem Cells: A Therapeutic Approach in Fertility Restoration in Premature Ovarian Insufficiency	45
Can miRNAs in MSCs-EVs Offer a Potential Treatment for Hypoxic-ischemic Encephalopathy?	45
Three-Dimension Co-culture of Hematopoietic Stem Cells and Differentiated Osteoblasts on Gallic Acid Grafted-Chitosan Scaffold as a Model of Hematopoietic Stem Cells Niche	45
The Role of PHF6 in Hematopoiesis and Hematologic Malignancies	44
Umbilical Cord Mesenchymal Stem/Stromal Cells and Low-Dose Obeticholic Acid as a Possible Combined Treatment for Liver Fibrosis	39
A Maverick Review of Common Stem/Progenitor Markers in Lung Development	38
MSC-Exosomes Carrying miRNA – Could they Enhance Tocilizumab Activity in Neuropathology of COVID-19?	38
Could Transplantation into the Thyroid Gland Benefit Pancreatic Islet Grafting in Unstable Type 1 Diabetes (T1DM), Complicated Type 2 Diabetes (T2DM), and Patients with Total Pancreatectomy?	37
Autologous CD133 + Cells and Laser Revascularization in patients with severe Ischemic Cardiomyopathy	37
Gene and Stem Cell-Based Therapies for Retinal Degenerative Diseases: Update, Challenges, and Future Directions	36
Disrupted Osteoblastogenesis and Mitochondrial Remodeling in MSCs from Patients with Cushing’s Syndrome	34
Exploring In Vitro Mesenchymal Stem Cell Osteodifferentiation via Vibrational Microspectroscopy: A Review	34

RBM47 is a Critical Regulator of Mouse Embryonic Stem Cell Differentiation	33
Comparison and Investigation of Exosomes from Human Amniotic Fluid Stem Cells and Human Breast Milk in Alleviating Neonatal Necrotizing Enterocolitis	32
In Vitro Simulated Neuronal Environmental Conditions Qualify Umbilical Cord Derived Highly Potent Stem Cells for Neuronal Differentiation	31
Regenerative Potential of Human Breast Milk: A Natural Reservoir of Nutrients, Bioactive Components and Stem cells	31
Identifying miRNA Signatures Associated with Pancreatic Islet Dysfunction in a FOXA2-Deficient iPSC Model	30
Cross Talk between Mesenchymal Stem/Stromal Cells and Innate Immunocytes Concerning Lupus Disease	30
Mesenchymal Stem Cell Derived Exosomes Suppress Neuronal Cell Ferroptosis Via lncGm36569/miR-5627-5p/FSP1 Axis in Acute Spinal Cord Injury	29
Nuclear Tubulin Enhances CXCR4 Transcription and Promotes Chemotaxis Through TCF12 Transcription Factor in human Hematopoietic Stem Cells	29
Generation of iPSC-Derived iNKT Cells with Pro-Hematopoietic Activity	29
Mesenchymal Stromal/Stem Cell Therapy Improves Salivary Flow Rate in Radiation-Induced Salivary Gland Hypofunction in Preclinical in vivo Models: A Systematic Review and Meta-Analysis	28
Stem Cells in Bone Tissue Engineering: Progress, Promises and Challenges	28
LncRNA RAD51-AS1 Regulates Human Bone Marrow Mesenchymal Stem Cells via Interaction with YBX1 to Ameliorate Osteoporosis	28
Bone Marrow Nucleated Cells and Bone Marrow-Derived CD271+ Mesenchymal Stem Cell in Treatment of Encephalopathy and Drug-Resistant Epilepsy	27
Telomeres and Mitochondrial Metabolism: Implications for Cellular Senescence and Age-related Diseases	26
Characteristics of Pooled Wharton’s Jelly Mesenchymal Stromal Cells (WJ-MSCs) and their Potential Role in Rheumatoid Arthritis Treatment	25
LNK/SH2B3 Loss Exacerbates the Development of Myeloproliferative Neoplasms in CBL-deficient Mice	25
Correction to: A Gutsy Move for Cell-Based Regenerative Medicine in Parkinson’s Disease: Targeting the Gut Microbiome to Sequester Inflammation and Neurotoxicity	25
Extracellular Adenosine (eAdo) - A2B Receptor Axis Inhibits in Nlrp3 Inflammasome-dependent Manner Trafficking of Hematopoietic Stem/progenitor Cells	24
Amniotic Membrane Transplantation for Wound Healing, Tissue Regeneration and Immune Modulation	24
Outgrowth Endothelial Cell Conditioned Medium Negates TNF-α-Evoked Cerebral Barrier Damage: A Reverse Translational Research to Explore Mechanisms	24
Organoids in Genetic Disorders: from Disease Modeling to Translational Applications	24
Spinal Cord Injury 2.0: Bridging the Gap Between Neurobiology, Technology, and Hope in the Era of Precision Medicine	23
Cellular Heterogeneity and Plasticity of Skin Epithelial Cells in Wound Healing and Tumorigenesis	23
The Protective Effect of Chronic Intermittent Hypobaric Hypoxia on Preventing the Destruction of CD34+ Haematopoietic Stem Cells in Aplastic Anaemia by Modulating the Th1/Th2 Balance	22
Efficacy and Safety of Mesenchymal Stromal Cells for Steroid-Refractory Acute Graft-versus-Host Disease: An Updated Meta-Analysis of Randomized Controlled Trials	22
miR-155-5p/Bmal1 Modulates the Senescence and Osteogenic Differentiation of Mouse BMSCs through the Hippo Signaling Pathway	22
Extracellular vesicles derived from umbilical cord mesenchymal stromal cells show enhanced anti-inflammatory properties via upregulation of miRNAs after pro-inflammatory priming	22
The Broken Cradle: Bone Marrow Stem Cell Niche Remodelling in Diabetes	22
Highly Engrafting Cord Blood Hematopoietic Stem Cells are Enriched in CD34+ Cell Population with High Autophagy Activity	22
Exploring the Protective Effect of Total Flavonoids from Semen Cuscutae on Ovarian Germline Stem Cells Based on Notch Signaling Pathway	22
DBC2 Attenuates the Stemness of CD44 Positive Gastric cancer Stem Cells by Suppressing Notch1 Signaling Pathway	22
Mechanosignaling YAP/TAZ-TEAD Axis Regulates the Immunomodulatory Properties of Mesenchymal Stem Cells	22
Human Melanoma Skin Cancer Models: A Step Towards Drug Testing & Target Therapy	21
Cirrhotic Patients Exhibit Remarkable Vascular Regenerative Profile One Month after Liver Transplantation	21
Stem Cells to Organoids: Pioneering the Future of Regenerative Therapies	20
Pancreatic Ductal Cell Heterogeneity: Insights into the Potential for β-Cell Regeneration in Diabetes	20
Dental Pulp Stem Cell Conditioned Medium Enhance Osteoblastic Differentiation and Bone Regeneration	20
Will Detecting Somatic Mutations Three Years Prior To Diagnosis Help Early Prediction of Cancer?	20
Therapeutic Potential of Oral-Derived Mesenchymal Stem Cells in Retinal Repair	20
Advances and Applications of Cancer Organoids in Drug Screening and Personalized Medicine	20
Nanovesicles from Adipose Derived Stem Cells Delay Hair Follicle Degeneration and Stimulate Regeneration: a Novel Therapeutic Strategy for Androgenetic Alopecia	20
Recipient Periodic Fasting Promotes Osteogenesis of Implanted Mesenchymal Stromal Cell Aggregates and Safeguards Diabetic Mandibular Bone Regeneration	19
Molecular Insights into Endometrial Cancer in Mice	19
The Molecular Dynamics of Extracellular Vesicles and their Protein Corona in the Secretomes of Stem Cells	19
rDNA Transcription in Developmental Diseases and Stem Cells	19
Novel Evidence That Alternative Pathway of Complement Cascade Activation is Required for Optimal Homing and Engraftment of Hematopoietic Stem/progenitor Cells	19
Pituitary Adenylate Cyclase-activating Polypeptide (PACAP) -derived Peptide MPAPO Stimulates Adipogenic Differentiation by Regulating the Early Stage of Adipogenesis and ERK Signaling Pathway	18
Global Trends of Exosomes Application in Clinical Trials: A Scoping Review	18
HYPOTHESIS: Do LRIG Proteins Regulate Stem Cell Quiescence by Promoting BMP Signaling?	18
Correction: Current Landscape of iPSC Haplobanks	18

Stem cell Derived Extracellular Vesicles to Alleviate ischemia-reperfusion Injury of Transplantable Organs. A Systematic Review	18
Role of Stem Cells in the Pathogenesis and Malignant Transformation of Oral Submucous Fibrosis	18
Immunomodulatory Properties of Mouse Mesenchymal Stromal/Stem Cells Upon Ectopic Expression of Immunoregulator Nanos2	18
Regulation Mechanisms and Maintenance Strategies of Stemness in Mesenchymal Stem Cells	18
CDX2 Promotes Hepatic Specification of hiPSC-derived Endoderm Through the PI3K–Akt–GSK3β Pathway for Improved Therapeutic Efficacy	17
Correction: Long-Term Protective Effect of Human Dystrophin Expressing Chimeric (DEC) Cell Therapy on Amelioration of Function of Cardiac, Respiratory and Skeletal Muscles in Duchenne Muscular Dystrop	17
The Impact of Metal Nanoparticles on the Immunoregulatory and Therapeutic Properties of Mesenchymal Stem Cells	17
Defect-adaptive Stem-cell-microcarrier Construct Promotes Tissue Repair in Rabbits with Knee Cartilage Defects	17
Human Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes Boost Functional Performance in an Animal Model of Multiple Sclerosis Through Recruiting Oligodendrocytes and Attenuating Gliosis	17
Rolipram and Electrical Stimulation Synergistically Promote Neuronal Differentiation of Adipose-derived Stromal Cells: an in Vitro Study	17
STAMBP is Required for Long-Term Maintenance of Neural Progenitor Cells Derived from hESCs	17
Expansion of Quiescent Hematopoietic Stem Cells under Stress and Nonstress Conditions in Mice	17
Periodontal Tissue Regeneration Therapy Using Stem Cells	17
Iron Oxide Nanoparticles in Mesenchymal Stem Cell Detection and Therapy	16
The miR151 and miR5100 Transfected Bone Marrow Stromal Cells Increase Myoblast Fusion in IGFBP2 Dependent Manner	16
Recent Advances in CRISPR/Cas9 Delivery Approaches for Therapeutic Gene Editing of Stem Cells	16
Stem Cells and Exosome Applications for Cutaneous Wound Healing: From Ground to Microgravity Environment	16
Insights on Three Dimensional Organoid Studies for Stem Cell Therapy in Regenerative Medicine	15
Chirality-induced Lineage Enforcement of Mechanosensitive Mesenchymal Stem Cells Across Germ Layer Boundaries	15
Phenotypic Transitions the Processes Involved in Regulation of Growth and Proangiogenic Properties of Stem Cells, Cancer Stem Cells and Circulating Tumor Cells	15
Cell Surface Membrane Lipid Rafts as Potent Regulators of Stem Cell Proliferation, Differentiation, Trafficking and Metabolism	15
Correction: Optimizing Generation of Stem Cell-Derived Islet Cells	15
The Effect of CagA Virulence Factor of H. Pylori on the Expression of Embryonic stem cell Transcription Factors in Gastric Tissues of Patients with Gastritis	15
Synergistic Effect of Human Chorionic Gonadotropin and Granulocyte Colony Stimulating Factor in the Mobilization of HSPCs Improves Overall Survival After PBSCT in a Preclinical Murine Model. Are We Fa	15
Production and Biological Effects of Extracellular Vesicles from Adipose-Derived Stem Cells Were Markedly Increased by Low-Intensity Ultrasound Stimulation for Promoting Diabetic Wound Healing	15
Correction to: Muscle Stem Cell Function Is Impaired in β2-Adrenoceptor Knockout Mice	15
Understanding the Angiogenic Characteristics of Clinical-Grade Mesenchymal Stromal Cells Isolated from Human Umbilical Cord	15
Unlocking the Epigenetic Symphony: Histone Acetylation Orchestration in Bone Remodeling and Diseases	14
Nicotinamide Riboside Promotes the Proliferation of Endogenous Neural Stem Cells to Repair Spinal Cord Injury	14
Cancer Stem Cells are Actually Stem Cells with Disordered Differentiation: the Monophyletic Origin of Cancer	14
Stem Cell-Based Regenerative Approaches for the Treatment of Cleft Lip and Palate: A Comprehensive Review	14
Latest Advanced Techniques for Improving Intestinal Organoids Limitations	14
Multiple Dimensions of using Mesenchymal Stem Cells for Treating Liver Diseases: From Bench to Beside	14
Targeting Strategies of Stem Cell-Derived Extracellular Vesicles in the Treatment of Cardiovascular Diseases	14
Heterogeneous Cells as well as Adipose-Derived Stromal Cells in Stromal Vascular Fraction Contribute to Enhance Anabolic and Inhibit Catabolic Factors in Osteoarthritis	14
The Regenerative Microenvironment of the Tissue Engineering for Urethral Strictures	14
Rif1 Regulates Self-Renewal and Impedes Mesendodermal Differentiation of Mouse Embryonic Stem Cells	14
Mechanistic Insights and Therapeutic Potential of Wnt5a Signaling in Alveolar Epithelial Cell Development and Bronchopulmonary Dysplasia	14
Effect of Constant Inflammation on In Vitro Expanded Adipose-derived Mesenchymal Stromal Cells	14
p53 Inhibition in Pancreatic Progenitors Enhances the Differentiation of Human Pluripotent Stem Cells into Pancreatic β-Cells	13
Stem Cell Markers LGR5, LGR4 and Their Immediate Signalling Partners are Dysregulated in Preeclampsia	13
Safety and Efficacy of DT-DEC01 Therapy in Duchenne Muscular Dystrophy Patients: A 12 - Month Follow-Up Study After Systemic Intraosseous Administration	13
A Brief Overview of Global Trends in MSC-Based Cell Therapy	13
Stem Cell Technology and Skin Disorders: from Stem Cell Biology to Clinical Applications	13
HucMSCs-derived Exosomes Promote Lung Development in Premature Birth via Wnt5a/ROCK1 Axis	13
Cancer Stem Cells and the Tumor Microenvironment: Targeting the Critical Crosstalk through Nanocarrier Systems	13
Research Progress on the Osteogenesis-Related Regulatory Mechanisms of Human Umbilical Cord Mesenchymal Stem Cells	13
SEC Injectable Solution Preserves Activated T Cells in Hypothermic Condition	13
From Inhibition to Rebound Resorption: Mechanisms behind Denosumab Discontinuation and Therapeutic Strategies	13
The Antioxidant Tetrapeptide Epitalon Enhances Delayed Wound Healing in an in Vitro Model of Diabetic Retinopathy	13
Preclinical Research of Stem Cells: Challenges and Progress	12
Stem Cell Therapy, Artificial Heart or Xenotransplantation: What will be New “Regenerative” Strategies in Heart Failure during the Next Decade?	12
Current Progress in Stem Cell Therapy for Male Infertility	12
BMSCs-derived Mitochondria Improve Osteoarthritis by Ameliorating Mitochondrial Dysfunction and Promoting Mitochondrial Biogenesis in Chondrocytes	12
Transforming Perspectives in Cardiac Cell Therapy: Hypothesis and Commentary Following Updated Results of a Pilot Study Investigating Very Long-Term Clinical Outcomes in Severe AMI Patients Following	12
Stem Cell-derived Extracellular Vesicles: A Promising Nano Delivery Platform to the Brain?	12
Outcomes Following Second Allogeneic Stem Cell Transplant for Graft Failure or Poor Graft Function: A Single Centre Experience	12
Mitochondria in Mesenchymal Stem Cells: Key to Fate Determination and Therapeutic Potential	12
HucMSC-EVs Facilitate In Vitro Development of Maternally Aged Preantral Follicles and Oocytes	12
In Vitro and in Vivo Bone Remodeling Models: Complementary Pieces of the same Puzzle	12
A Novel Splicing Mutation c.335–1 G > A in the Cardiac Transcription Factor NKX2-5 Leads to Familial Atrial Septal Defect Through miR-19 and PYK2	12
Time-resolved Small-RNA Sequencing Identifies MicroRNAs Critical for Formation of Embryonic Stem Cells from the Inner Cell Mass of Mouse Embryos	12
Development and Applications of Organoids in Gynecological Diseases	12
Human iPSC-Derived Neural Models for Studying Alzheimer’s Disease: from Neural Stem Cells to Cerebral Organoids	12
Effect of Octamer-Binding Transcription Factor 4 Overexpression on the Neural Induction of Human Dental Pulp Stem Cells	12
Evaluation of the Efficacy of Stem Cells Therapy in the Periodontal Regeneration: A Meta-Analysis and Mendelian Randomization Study	12
Stem Cell Based Regenerative Applications for the Management of Diabetes Induced Systemic Complications	11
Mesenchymal Stem Cell-Derived Extracellular Vesicle Therapy for Asthma in Murine Models: A Systematic Review and Meta-analysis	11
Validation of BCMA-CD19 Compound CAR-T Therapy in SLE Overlap Syndrome: Over 1.5-Year Follow-Up	11
Adipose-Derived Stem Cells at the Crossroads of Obesity and Cancer	11
Granulopoietic Dysregulation in a Patient-Tailored Mouse Model of Barth Syndrome	11
Progesterone receptor is constitutively expressed in induced Pluripotent Stem Cells (iPSCs)	11
Culturing Conditions Dictate the Composition and Pathways Enrichment of Human and Rat Perirenal Adipose-Derived Stromal Cells’ Secretomes	11
Application of Human Stem Cell Derived Retinal Organoids in the Exploration of the Mechanisms of Early Retinal Development	11
From Pluripotent Stem Cells to Organoids and Bioprinting: Recent Advances in Dental Epithelium and Ameloblast Models to Study Tooth Biology and Regeneration	11
Metabolic Control of Stem Cell Function: Insights into Amino Acid-Driven Mechanisms	11
Do PGCCs in Solid Tumors Appear Due to Treatment-related Stress or Clonal Expansion of CSCs that Survive Oncotherapy?	11
BMSC-exosomes miR-25-3p Regulates the p53 Signaling Pathway Through PTEN to Inhibit Cell Apoptosis and Ameliorate Liver Ischemia‒reperfusion Injury	11
Unlocking a Decade of Research on Embryo-Derived Extracellular Vesicles: Discoveries Made and Paths Ahead	11
Stem Cell for Cancer Immunotherapy: Current Approaches and Challenges	11

Empagliflozin Reduces High Glucose-Induced Cardiomyopathy in hiPSC-Derived Cardiomyocytes	11
Characterization of the Proteins Secreted by Equine Muscle-Derived Mesenchymal Stem Cells Exposed to Cartilage Explants in Osteoarthritis Model	11
Chimeric Antigen Receptor (CAR)-Based Cell Therapy for Type 1 Diabetes Mellitus (T1DM); Current Progress and Future Approaches	10
Differentiated Embryonic Neurospheres from Familial Alzheimer’s Disease Model Show Innate Immune and Glial Cell Responses	10
Biomechanical Characterization of Retinal Pigment Epitheliums Derived from hPSCs Using Atomic Force Microscopy	10
Advances and Challenges in Constructing Bone Organoids Using Cells Derived from Human Pluripotent Stem Cells: A Review	10
Research update of adipose tissue-based therapies in regenerative dermatology	10
Compatibility of Hepatocyte Growth Factor, Adipose-Derived Mesenchymal Stem Cells, and Dermal Fillers for the Treatment of Vocal Fold Scar	10
Pluripotent Stem Cell-derived Dopaminergic Neurons for Studying Developmental Neurotoxicity	10
Region-Specific Adult Neural Stem Cell Niches of the Mediobasal Hypothalamus and Medulla Oblongata	10
Static Magnetic Fields Promote Generation of Muscle Lineage Cells from Pluripotent Stem Cells and Myoblasts	10
Wnt10b Regulation of Hair Follicle Development, Regeneration, and Skin Diseases	10
Inner Ear Organoid as a Preclinical Model of Hearing Regeneration: Progress and Applications	10
LED-Modified Mesenchymal Stem Cells Improve Post-Infarction Heart Failure	10
Human Umbilical Cord Mesenchymal Stem Cells Promote Anti-Inflammation and Angiogenesis by Targeting Macrophages in a Rat Uterine Scar Model	10
Retinal Organoids from Induced Pluripotent Stem Cells of Patients with Inherited Retinal Diseases: A Systematic Review	10
Mesenchymal Stromal Cells: Bridging the Gaps in Hematologic Disease Therapy	9
Efficacy of Human Embryonic Stem Cells Compared to Adipose Tissue-Derived Human Mesenchymal Stem/Stromal Cells for Repair of Murine Post-Stenotic Kidneys	9
S100A6 as a Constituent and Potential Marker of Adult and Cancer Stem Cells	9
Single-cell Profiling of Reprogrammed Human Neural Stem Cells Unveils High Similarity to Neural Progenitors in the Developing Central Nervous System	9
Elevating Dermatology Beyond Aesthetics: Perinatal-Derived Advancements for Rejuvenation, Alopecia Strategies, Scar Therapies, and Progressive Wound Healing	9
Stem Cells in the Tumor Immune Microenvironment –Part of the Cure or Part of the Disease? Ontogeny and Dichotomy of Stem and Immune Cells has Led to better Understanding	9
Bone Marrow Mesenchymal Stem Cells Reversed Ovarian Aging-related m6A RNA Methylation Modification Profile in Aged Granulosa Cells	9
WNT Signaling in Stem Cells: A Look into the Non-Canonical Pathway	9
UTF1 Expression is Important for the Generation and Maintenance of Human iPSCs	9
Oxygen Handling Practices for in Vitro Human Pluripotent Stem Cell Cardiomyocyte Differentiation: A Scoping Literature Review	9
The Effect of Mechanical Stretch on the Maturation of Cardiomyocytes	9
Loss of Epidermal Homeostasis Underlies the Development of Squamous Cell Carcinoma	9
Intracellular Complement (Complosome) is Expressed in Several Types of Human Adult Bone Marrow—Derived Stem Cells	9
Delivery of Stem Cells and BMP-2 With Functionalized Self-Assembling Peptide Enhances Regeneration of Infarcted Myocardium	9
Compelling Reasons to Perform Basic and Pre-clinical Research on Germline Genome Editing	9
Combination Therapy of Stem Cell-derived Exosomes and Biomaterials in the Wound Healing	9
Artificial Mitochondrial Transfer (AMT) for the Management of Age-related Musculoskeletal Degenerative Disorders: An Emerging Avenue for Bone and Cartilage Metabolism Regulation	9