OOIR: Observatory of International Research

Papers

(The TQCC of International Journal of Pharmaceutics-X is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
Tailored ASD destabilization - Balancing shelf life stability and dissolution performance with hydroxypropyl cellulose	60
Exploring high-throughput synchrotron X-Ray powder diffraction for the structural analysis of pharmaceuticals	24
Oral etoposide and zosuquidar bioavailability in rats: Effect of co-administration and in vitro-in vivo correlation of P-glycoprotein inhibition	22
Rationalized landscape on protein-based cancer nanomedicine: Recent progress and challenges	18
Enabling formulations of aprepitant: in vitro and in vivo comparison of nanocrystalline, amorphous and deep eutectic solvent based formulations	15
Continuous direct compression: Development of an empirical predictive model and challenges regarding PAT implementation	14
Exploiting recent trends for the synthesis and surface functionalization of mesoporous silica nanoparticles towards biomedical applications	14
Everolimus-encapsulation in Pluronic P123 self-assembled micelles as drug delivery systems for drug-coated balloons	12
Autoencoder-based inverse design and surrogate-based optimization of an integrated wet granulation manufacturing process	12
Polydopamine-activated celastrol carbon dots for synergistic chemotherapy-photothermal therapy of tumors	11
Erratum regarding missing Conflict of Interest statements in previously published articles	10
Formulating a heat- and shear-labile drug in an amorphous solid dispersion: Balancing drug degradation and crystallinity	10
Enhancing oocyte in vitro maturation and quality by melatonin/bilirubin cationic nanoparticles: A promising strategy for assisted reproduction techniques	9
Impact of process stress on protein stability in highly-loaded solid protein/PEG formulations from small-scale melt extrusion	9
At-line porosity sensing for non-destructive disintegration testing in immediate release tablets	9
Polycaprolactone – Vitamin E TPGS micelles for delivery of paclitaxel: In vitro and in vivo evaluation	8
Corrigendum to “Impact of polymer chemistry on critical quality attributes of selective laser sintering 3D printed solid oral dosage forms” [International Journal of Pharmaceutics:X Volume 6 (2023) 10	8
Formulation development of itraconazole PEGylated nano-lipid carriers for pulmonary aspergillosis using hot-melt extrusion technology	8
Corrigendum to “Quantitative comparison of the protein corona of nanoparticles with different matrices” [Int J Pharm X 2022 Oct 21;4: 100136]	7
Spanlastic-laden nanogel as a plausible platform for dermal delivery of bimatoprost with superior cutaneous deposition and hair regrowth efficiency in androgenic alopecia	7
Formulation of multicomponent inclusion complex of cyclodextrin-amino acid with Chrysin: Physicochemical characterization, cell viability and apoptosis assessment in human primary glioblastoma cell li	7
Editorial Board	7
Preparation of chitosan-coated hollow tin dioxide nanoparticles and their application in improving the oral bioavailability of febuxostat	7
Predicting pharmaceutical inkjet printing outcomes using machine learning	7
A network of regulatory innovations to improve FDA quality assessments of human drug applications	7

A new engineering process of biodegradable polymeric solid implants for ultra-long-acting drug delivery	6
Preservative-free electrospun nanofibrous inserts for sustained delivery of ceftazidime; design, characterization and pharmacokinetic investigation in rabbit's eye	6
HSPiP and QbD oriented optimized stearylamine-elastic liposomes for topical delivery of ketoconazole to treat deep seated fungal infections: In vitro and ex vivo evaluations	6
A tabletability change classification system in supporting the tablet formulation design via the roll compaction and dry granulation process	6
Synergistic effect of doxorubicin lauroyl hydrazone derivative delivered by α-tocopherol succinate micelles for the treatment of glioblastoma	6
Multifunctional poloxamer-based thermo-responsive hydrogel loaded with human lactoferricin niosomes: In vitro study on anti-bacterial activity, accelerate wound healing, and anti-inflammation	6
Box Behnken optimization of cubosomes for enhancing the anticancer activity of metformin: Design, characterization, and in-vitro cell proliferation assay on MDA-MB-231 breast and LOVO colon cancer cel	6
Stability of Dexamethasone during Hot-Melt Extrusion of Filaments based on Eudragit® RS, Ethyl Cellulose and Polyethylene Oxide	6
Repurposing celecoxib for colorectal cancer targeting via pH-triggered ultra-elastic nanovesicles: Pronounced efficacy through up-regulation of Wnt/β-catenin pathway in DMH-induced tumorigenesis	6
A model-based optimization strategy to achieve fast and robust freeze-drying cycles	6
Nanoparticles design considerations to co-deliver nucleic acids and anti-cancer drugs for chemoresistance reversal	5
Use of simulated vaginal and menstrual fluids to model in vivo discolouration of silicone elastomer vaginal rings	5
Atorvastatin-loaded emulsomes foam as a topical antifungal formulation	5
Formulation, optimization, in-vivo biodistribution studies and histopathological safety assessment of duloxetine HCl-loaded ultra-elastic nanovesicles for antidepressant effect after intranasal and tr	5
Editorial board	5
RETRACTED: Development of thermosensitive hydrogel of Amphotericin-B and Lactoferrin combination-loaded PLGA-PEG-PEI nanoparticles for potential eradication of ocular fungal infections: In-vitro, ex-v	5
Multifunctional Bi2S3-Au nanoclusters for fluorescence/infrared thermal imaging guided photothermal therapy	5
The shelf life of ASDs: 2. Predicting the shelf life at storage conditions	5
Formulation, optimization and evaluation of ocular gel containing nebivolol Hcl-loaded ultradeformable spanlastics nanovesicles: In vitro and in vivo studies	5
RP-HPLC-CAD method for the rapid analysis of lipids used in lipid nanoparticles derived from dual centrifugation	5
Towards a better understanding of thermally treated polycarbophil matrix tablets for controlled release	5
Nanoscale metal-organic frameworks for the delivery of nucleic acids to cancer cells	4
Ocular mucoadhesive and biodegradable spanlastics loaded cationic spongy insert for enhancing and sustaining the anti-inflammatory effect of prednisolone Na phosphate; Preparation, I-optimal optimizat	4
The use of heat to deliver fentanyl via pulmonary drug delivery	4
The impact of solvent selection on the characteristics of niosome nanoparticles prepared by microfluidic mixing	4
How bulk fluid renewal can affect in vitro drug release from PLGA implants: Importance of the experimental set-up	4
Development and optimization of vildagliptin solid lipid nanoparticles loaded ocuserts for controlled ocular delivery: A promising approach towards treating diabetic retinopathy	4
Reactive oxygen species responsive double-locked liposome collaborative photodynamic therapy for reducing electrical conduction recurrence after radiofrequency catheter ablation	4
Process intensification of pharmaceutical powder blending at commercial throughputs by utilizing semi-continuous mini-blending	4
Oxidation of polysorbates – An underestimated degradation pathway?	4
β-Cyclodextrin metal-organic framework as a green carrier to improve the dissolution, bioavailability, and liver protective effect of luteolin	4
The Dynamic Intestinal Absorption Model (Diamod®), an in vitro tool to study the interconnected kinetics of gastrointestinal solubility, supersaturation, precipitation, and intestinal permeation proce	4
End-to-end approach for the characterization and control of product-related impurities in T cell bispecific antibody preparations	3
A case study on decentralized manufacturing of 3D printed medicines	3
Integrating pressure sensor control into semi-solid extrusion 3D printing to optimize medicine manufacturing	3
Quantitative comparison of the protein corona of nanoparticles with different matrices	3
From design to 3D printing: A proof-of-concept study for multiple unit particle systems (MUPS) printed by dual extrusion fused filament fabrication	3
Feed factor profile prediction model for two-component mixed powder in the twin-screw feeder	3
Editorial board	3
Characterization and quantification of the interaction between the NFL-TBS.40‐63 peptide and lipid nanocapsules	3
Functional candesartan loaded lipid nanoparticles for the control of diabetes-associated stroke: In vitro and in vivo studies	3
Designing fisetin nanocrystals for enhanced in cellulo anti-angiogenic and anticancer efficacy	3
Spanlastic-laden in situ gel as a promising approach for ocular delivery of Levofloxacin: In-vitro characterization, microbiological assessment, corneal permeability and in-vivo study	3
Characterisation of niosome nanoparticles prepared by microfluidic mixing for drug delivery	3
Non-invasive caffeinated-nanovesicles as adipocytes-targeted therapy for cellulite and localized fats	3
In vitro and in vivo assessment of hydroxypropyl cellulose as functional additive for enabling formulations containing itraconazole	3
A drug repurposing approach of Atorvastatin calcium for its antiproliferative activity for effective treatment of breast cancer: In vitro and in vivo assessment	3
Releasing fast and slow: Non-destructive prediction of density and drug release from SLS 3D printed tablets using NIR spectroscopy	3
The combined effect of permeation enhancement and proteolysis inhibition on the systemic exposure of orally administrated peptides: Salcaprozate sodium, soybean trypsin inhibitor, and teriparatide stu	3
In vitro synergistic activity of cisplatin and EGFR-targeted nanomedicine of anti-Bcl-xL siRNA in a non-small lung cancer cell line model	3

M1 macrophage-membrane-cloaked paclitaxel/β-elemene nanoparticles targeting cervical cancer for enhanced therapy	3
Modelling intramuscular drug fate in vitro with tissue-relevant biomimetic hydrogels	3
Tablet formulation development focusing on the functional behaviour of water uptake and swelling	3
Compression of amorphous solid dispersions prepared by hot-melt extrusion, spray drying and vacuum drum drying	3
Biological activity of gold nanoparticles combined with the NFL-TBS.40-63 peptide, or with other cell penetrating peptides, on rat glioblastoma cells	3
Experimental determination of the velocity distribution in USP Apparatus 1 (basket apparatus) using Particle Image Velocimetry (PIV)	3
Stimuli-sensitive biomimetic nanoparticles for the inhibition of breast cancer recurrence and pulmonary metastasis	3
Prodigiosin hydrogel to promote healing of trauma-infected multidrug-resistant Staphylococcus aureus mice wounds	3
Drug release from PLGA microparticles can be slowed down by a surrounding hydrogel	3
WITHDRAWN: The effect of particle size on the sublimation behavior of butylhydroxytoluene as antioxidant in tablets during storage and coating	3
Transfer of a rational formulation and process development approach for 2D inks for pharmaceutical 2D and 3D printing	3
Investigation on the self-assembly of the NFL-TBS.40-63 peptide and its interaction with gold nanoparticles as a delivery agent for glioblastoma	3