OOIR: Observatory of International Research

Papers

(The median citation count of International Journal of Pharmaceutics-X is 1. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-03-01 to 2024-03-01.)

Article	Citations
Bacterially sensitive nanoparticle-based dissolving microneedles of doxycycline for enhanced treatment of bacterial biofilm skin infection: A proof of concept study	35
WITHDRAWN: Advances in drug delivery systems: Work in progress still needed?	18
Digitalization in pharmaceutical industry: What to focus on under the digital implementation process?	16
Influence of probiotic bacteria on gut microbiota composition and gut wall function in an in-vitro model in patients with Parkinson's disease	16
Liposome mimicking polymersomes; A comparative study of the merits of polymersomes in terms of formulation and stability	15
Additive manufacturing technologies with emphasis on stereolithography 3D printing in pharmaceutical and medical applications: A review	15
Physical stability and release properties of lumefantrine amorphous solid dispersion granules prepared by a simple solvent evaporation approach	14
Exploiting recent trends for the synthesis and surface functionalization of mesoporous silica nanoparticles towards biomedical applications	12
A novel architecture for achieving high drug loading in amorphous spray dried dispersion tablets	10
Phase behavior of ASDs based on hydroxypropyl cellulose	9
Intravesical drug delivery approaches for improved therapy of urinary bladder diseases	9
In vivo pharmacokinetic study of remdesivir dry powder for inhalation in hamsters	8
Tableting of mini-tablets in comparison with conventionally sized tablets: A comparison of tableting properties and tablet dimensions	8
Mean yield pressure from the in-die Heckel analysis is a reliable plasticity parameter	7
Compression of amorphous solid dispersions prepared by hot-melt extrusion, spray drying and vacuum drum drying	7
Predicting pharmaceutical inkjet printing outcomes using machine learning	6
Accelerating 3D printing of pharmaceutical products using machine learning	6
Starch nanoparticles improve curcumin-induced production of anti-inflammatory cytokines in intestinal epithelial cells	6
A micro-XRT image analysis and machine learning methodology for the characterisation of multi-particulate capsule formulations	6
Formulation development of itraconazole PEGylated nano-lipid carriers for pulmonary aspergillosis using hot-melt extrusion technology	6
Coated polymeric needles for rapid and deep intradermal delivery	5
Influence of drug loading on the physical stability of phospholipid-stabilised colloidal lipid emulsions	5
Anti-inflammatory effects of acacia and guar gum in 5-amino salicylic acid formulations in experimental colitis	5
A new engineering process of biodegradable polymeric solid implants for ultra-long-acting drug delivery	5
Feasibility of In-line monitoring of critical coating quality attributes via OCT: Thickness, variability, film homogeneity and roughness	5

The use of X-ray microtomography to investigate the microstructure of pharmaceutical tablets: Potentials and comparison to common physical methods	5
Predicting process design spaces for spray drying amorphous solid dispersions	5
Efficacy optimization of low frequency microbubble-mediated sonoporation as a drug delivery platform to cancer cells	5
Formulating a heat- and shear-labile drug in an amorphous solid dispersion: Balancing drug degradation and crystallinity	5
3D printed infliximab suppositories for rectal biologic delivery	4
Enhancing efficacy of gemcitabine in pancreatic patient-derived xenograft mouse models	4
Continuous twin screw granulation: Impact of microcrystalline cellulose batch-to-batch variability during granulation and drying – A QbD approach	4
In vitro and in vivo assessment of hydroxypropyl cellulose as functional additive for enabling formulations containing itraconazole	4
Polymeric micelles loaded with carfilzomib increase tolerability in a humanized bone marrow-like scaffold mouse model	4
Cod liver oil nano-structured lipid carriers (Cod-NLCs) as a promising platform for nose to brain delivery: Preparation, in vitro optimization, ex vivo cytotoxicity & in vivo biodistribution utili	4
Deep convolutional neural networks: Outperforming established algorithms in the evaluation of industrial optical coherence tomography (OCT) images of pharmaceutical coatings	4
Dexamethasone-loaded cochlear implants: How to provide a desired “burst release”	4
Influence of process and formulation parameters on the preparation of solid lipid nanoparticles by dual centrifugation	4
Towards 4D printing in pharmaceutics	4
Biological activity of gold nanoparticles combined with the NFL-TBS.40-63 peptide, or with other cell penetrating peptides, on rat glioblastoma cells	4
Inkjet drug printing onto contact lenses: Deposition optimisation and non-destructive dose verification	3
Synergistic effect of doxorubicin lauroyl hydrazone derivative delivered by α-tocopherol succinate micelles for the treatment of glioblastoma	3
Tablet formulation development focusing on the functional behaviour of water uptake and swelling	3
Simultaneous fabrication of multiple tablets within seconds using tomographic volumetric 3D printing	3
Development of 3D-printed vaginal devices containing metronidazole for alternative bacterial vaginosis treatment	3
Classification of scanning electron microscope images of pharmaceutical excipients using deep convolutional neural networks with transfer learning	3
Determination of the physical state of a drug in amorphous solid dispersions using artificial neural networks and ATR-FTIR spectroscopy	3
Preparation, characterization, and pharmacokinetics of rivaroxaban cocrystals with enhanced in vitro and in vivo properties in beagle dogs	3
Downstream processing of spray-dried ASD with hypromellose acetate succinate – Roller compaction and subsequent compression into high ASD load tablets	3
Modelling intramuscular drug fate in vitro with tissue-relevant biomimetic hydrogels	3
3D printed matrix solid forms: Can the drug solubility and dose customisation affect their controlled release behaviour?	3
Experimental determination of the velocity distribution in USP Apparatus 1 (basket apparatus) using Particle Image Velocimetry (PIV)	3
Development of thermosensitive hydrogel of Amphotericin-B and Lactoferrin combination-loaded PLGA-PEG-PEI nanoparticles for potential eradication of ocular fungal infections: In-vitro, ex-vivo and in-	3
Drug crystal growth in ternary amorphous solid dispersions: Effect of surfactants and polymeric matrix-carriers	3
Formulation, optimization, in-vivo biodistribution studies and histopathological safety assessment of duloxetine HCl-loaded ultra-elastic nanovesicles for antidepressant effect after intranasal and tr	3
To infinity and beyond: Strategies for fabricating medicines in outer space	3
Designing fisetin nanocrystals for enhanced in cellulo anti-angiogenic and anticancer efficacy	3
The applications of machine learning to predict the forming of chemically stable amorphous solid dispersions prepared by hot-melt extrusion	3
A potent novel vaccine adjuvant based on straight polyacrylate	3
Silicone elastomer formulations for improved performance of a multipurpose vaginal ring releasing dapivirine and levonorgestrel	3
Development and evaluation of a composite dosage form containing desmopressin acetate for buccal administration	2
Nanoparticles from Gantrez-based conjugates for the oral delivery of camptothecin	2
The shelf life of ASDs: 2. Predicting the shelf life at storage conditions	2
3D printed multi-drug-loaded suppositories for acute severe ulcerative colitis	2
Xyloglucan based mucosal nanovaccine for immunological protection against brucellosis developed by supercritical fluid technology	2
Integrating pressure sensor control into semi-solid extrusion 3D printing to optimize medicine manufacturing	2
Terahertz time-domain spectroscopy for powder compact porosity and pore shape measurements: An error analysis of the anisotropic bruggeman model	2
Use of simulated vaginal and menstrual fluids to model in vivo discolouration of silicone elastomer vaginal rings	2
Nanoparticles design considerations to co-deliver nucleic acids and anti-cancer drugs for chemoresistance reversal	2
A case study on decentralized manufacturing of 3D printed medicines	2
Investigation on the self-assembly of the NFL-TBS.40-63 peptide and its interaction with gold nanoparticles as a delivery agent for glioblastoma	2
Noninvasive characterization (EPR, μCT, NMR) of 3D PLA electrospun fiber sponges for controlled drug delivery	2
Tailored hyaluronic acid-based nanogels as theranostic boron delivery systems for boron neutron cancer therapy	2
End-point determination of heterogeneous formulations using inline torque measurements for a high-shear wet granulation process	2
Releasing fast and slow: Non-destructive prediction of density and drug release from SLS 3D printed tablets using NIR spectroscopy	2

Inhalable aerosol microparticles with low carrier dosage and high fine particle fraction prepared by spray-freeze-drying	2
Towards better understanding of the influence of process parameters in roll compaction/dry granulation on throughput, ribbon microhardness and granule failure load	2
Characterisation of niosome nanoparticles prepared by microfluidic mixing for drug delivery	2
The interplay of dissolution, solution crystallization and solid-state transformation of amorphous indomethacin in aqueous solution	2
Atorvastatin-loaded emulsomes foam as a topical antifungal formulation	2
Poly(pseudo)rotaxanes formed by mixed micelles and α-cyclodextrin enhance terbinafine nail permeation to deeper layers	2
Boost of solubility and supersaturation of celecoxib via synergistic interactions of methacrylic acid-ethyl acrylate copolymer (1:1) and hydroxypropyl cellulose in ternary amorphous solid dispersions	1
Polymeric nanocomposite hydrogel scaffold for jawbone regeneration: The role of rosuvastatin calcium-loaded silica nanoparticles	1
Oxidation of polysorbates – An underestimated degradation pathway?	1
The effect of exhalation before the inhalation of dry powder aerosol drugs on the breathing parameters, emitted doses and aerosol size distributions	1
Characterization and quantification of the interaction between the NFL-TBS.40‐63 peptide and lipid nanocapsules	1
Enabling formulations of aprepitant: in vitro and in vivo comparison of nanocrystalline, amorphous and deep eutectic solvent based formulations	1
WITHDRAWN: Specific protein-protein interactions limit the cutaneous iontophoretic transport of interferon beta-1B and a poly-ARG interferon beta-1B analogue	1
The effect of lung emptying before the inhalation of aerosol drugs on drug deposition in the respiratory system	1
X-ray imaging: A potential enabler of automated particulate detection and cake-structure analysis in lyophilized products?	1
The use of heat to deliver fentanyl via pulmonary drug delivery	1
The Dynamic Intestinal Absorption Model (Diamod®), an in vitro tool to study the interconnected kinetics of gastrointestinal solubility, supersaturation, precipitation, and intestinal permeation proce	1
Chicken embryo model for in vivo acute toxicological and antitumor efficacy evaluation of lipid nanocarrier containing doxorubicin	1
Ethoxy acetalated dextran nanoparticles for drug delivery: A comparative study of formulation methods	1
The effect of excipient particle size on the reduction of compactibility after roller compaction	1
Towards predicting the product quality in hot-melt extrusion: Small scale extrusion	1
Investigating the role of excipients on the physical stability of directly compressed tablets	1
Impact of polymer chemistry on critical quality attributes of selective laser sintering 3D printed solid oral dosage forms	1
Drop-on-powder 3D printing of amorphous high dose oral dosage forms: Process development, opportunities and printing limitations	1
Preparation and in vitro evaluation of hot-melt extruded pectin-based pellets containing ketoprofen for colon targeting	1
Impact of mucus modulation by N-acetylcysteine on nanoparticle toxicity	1
The combined effect of permeation enhancement and proteolysis inhibition on the systemic exposure of orally administrated peptides: Salcaprozate sodium, soybean trypsin inhibitor, and teriparatide stu	1
Towards predicting the product quality in hot-melt extrusion: Pilot plant scale extrusion	1
Dual-targeting inhibition of TNFR1 for alleviating rheumatoid arthritis by a novel composite nucleic acid nanodrug	1
Model-based optimization of the primary drying phase of oral lyophilizates	1
The impact of solvent selection on the characteristics of niosome nanoparticles prepared by microfluidic mixing	1
On the relationship between blend state and dispersibility of adhesive mixtures containing active pharmaceutical ingredients	1
The characteristics and biological activity enhancements of melatonin encapsulations for skin care product applications	1
How bulk fluid renewal can affect in vitro drug release from PLGA implants: Importance of the experimental set-up	1
Corrigendum to ‘LC-MS metabolomics comparisons of cancer cell and macrophage responses to methotrexate and polymer-encapsulated methotrexate’ [International Journal of Pharmaceutics: X Volume 1 (2019)	1
Influence of high pressure compaction on solubility and intrinsic dissolution of ibuprofen binary mixtures employing standard excipients	1
Enhanced stability and skin permeation of ibuprofen-loaded solid lipid nanoparticles based binary solid lipid matrix: Effect of surfactant and lipid compositions	1
Identification of novel cyanoacrylate monomers for use in nanoparticle drug delivery systems prepared by miniemulsion polymerisation – A multistep screening approach	1
Tackling acne vulgaris by fabrication of tazarotene-loaded essential oil-based microemulsion: In vitro and in vivo evaluation	1
End-to-end approach for the characterization and control of product-related impurities in T cell bispecific antibody preparations	1
The effect of mAb and excipient cryoconcentration on long-term frozen storage stability – part 2: Aggregate formation and oxidation	1
Dual-effects of caffeinated hyalurosomes as a nano-cosmeceutical gel counteracting UV-induced skin ageing	1
Novel nasal niosomes loaded with lacosamide and coated with chitosan: A possible pathway to target the brain to control partial-onset seizures	1
The effect of mAb and excipient cryoconcentration on long-term frozen storage stability – Part 1: Higher molecular weight species and subvisible particle formation	1