OOIR: Observatory of International Research

Papers

(The median citation count of International Journal of Pharmaceutics-X is 1. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Bacterially sensitive nanoparticle-based dissolving microneedles of doxycycline for enhanced treatment of bacterial biofilm skin infection: A proof of concept study	34
Additive manufacturing technologies with emphasis on stereolithography 3D printing in pharmaceutical and medical applications: A review	31
Digitalization in pharmaceutical industry: What to focus on under the digital implementation process?	24
WITHDRAWN: Advances in drug delivery systems: Work in progress still needed?	18
Exploiting recent trends for the synthesis and surface functionalization of mesoporous silica nanoparticles towards biomedical applications	16
Influence of probiotic bacteria on gut microbiota composition and gut wall function in an in-vitro model in patients with Parkinson's disease	14
Physical stability and release properties of lumefantrine amorphous solid dispersion granules prepared by a simple solvent evaporation approach	13
Liposome mimicking polymersomes; A comparative study of the merits of polymersomes in terms of formulation and stability	12
Accelerating 3D printing of pharmaceutical products using machine learning	12
Predicting pharmaceutical inkjet printing outcomes using machine learning	10
Mean yield pressure from the in-die Heckel analysis is a reliable plasticity parameter	9
RETRACTED: Development of thermosensitive hydrogel of Amphotericin-B and Lactoferrin combination-loaded PLGA-PEG-PEI nanoparticles for potential eradication of ocular fungal infections: In-vitro, ex-v	9
In vivo pharmacokinetic study of remdesivir dry powder for inhalation in hamsters	9
A novel architecture for achieving high drug loading in amorphous spray dried dispersion tablets	9
A new engineering process of biodegradable polymeric solid implants for ultra-long-acting drug delivery	8
Phase behavior of ASDs based on hydroxypropyl cellulose	7
Simultaneous fabrication of multiple tablets within seconds using tomographic volumetric 3D printing	7
Intravesical drug delivery approaches for improved therapy of urinary bladder diseases	6
Towards 4D printing in pharmaceutics	6
3D printed infliximab suppositories for rectal biologic delivery	6
Compression of amorphous solid dispersions prepared by hot-melt extrusion, spray drying and vacuum drum drying	6
Starch nanoparticles improve curcumin-induced production of anti-inflammatory cytokines in intestinal epithelial cells	6
Anti-inflammatory effects of acacia and guar gum in 5-amino salicylic acid formulations in experimental colitis	6
Cod liver oil nano-structured lipid carriers (Cod-NLCs) as a promising platform for nose to brain delivery: Preparation, in vitro optimization, ex vivo cytotoxicity & in vivo biodistribution utili	6
To infinity and beyond: Strategies for fabricating medicines in outer space	6

Formulation development of itraconazole PEGylated nano-lipid carriers for pulmonary aspergillosis using hot-melt extrusion technology	6
The use of X-ray microtomography to investigate the microstructure of pharmaceutical tablets: Potentials and comparison to common physical methods	6
The applications of machine learning to predict the forming of chemically stable amorphous solid dispersions prepared by hot-melt extrusion	5
Modelling intramuscular drug fate in vitro with tissue-relevant biomimetic hydrogels	5
Efficacy optimization of low frequency microbubble-mediated sonoporation as a drug delivery platform to cancer cells	5
Polymeric micelles loaded with carfilzomib increase tolerability in a humanized bone marrow-like scaffold mouse model	5
Preparation, characterization, and pharmacokinetics of rivaroxaban cocrystals with enhanced in vitro and in vivo properties in beagle dogs	5
Designing fisetin nanocrystals for enhanced in cellulo anti-angiogenic and anticancer efficacy	5
Xyloglucan based mucosal nanovaccine for immunological protection against brucellosis developed by supercritical fluid technology	5
Tableting of mini-tablets in comparison with conventionally sized tablets: A comparison of tableting properties and tablet dimensions	5
Releasing fast and slow: Non-destructive prediction of density and drug release from SLS 3D printed tablets using NIR spectroscopy	5
Coated polymeric needles for rapid and deep intradermal delivery	5
A micro-XRT image analysis and machine learning methodology for the characterisation of multi-particulate capsule formulations	5
Deep convolutional neural networks: Outperforming established algorithms in the evaluation of industrial optical coherence tomography (OCT) images of pharmaceutical coatings	5
Biological activity of gold nanoparticles combined with the NFL-TBS.40-63 peptide, or with other cell penetrating peptides, on rat glioblastoma cells	5
Formulating a heat- and shear-labile drug in an amorphous solid dispersion: Balancing drug degradation and crystallinity	4
Predicting process design spaces for spray drying amorphous solid dispersions	4
Synergistic effect of doxorubicin lauroyl hydrazone derivative delivered by α-tocopherol succinate micelles for the treatment of glioblastoma	4
Feasibility of In-line monitoring of critical coating quality attributes via OCT: Thickness, variability, film homogeneity and roughness	4
Characterisation of niosome nanoparticles prepared by microfluidic mixing for drug delivery	4
Inkjet drug printing onto contact lenses: Deposition optimisation and non-destructive dose verification	4
Magnetic nanosystem a tool for targeted delivery and diagnostic application: Current challenges and recent advancement	4
Classification of scanning electron microscope images of pharmaceutical excipients using deep convolutional neural networks with transfer learning	4
Formulation, optimization and evaluation of ocular gel containing nebivolol Hcl-loaded ultradeformable spanlastics nanovesicles: In vitro and in vivo studies	4
Enhancing efficacy of gemcitabine in pancreatic patient-derived xenograft mouse models	4
Development of 3D-printed vaginal devices containing metronidazole for alternative bacterial vaginosis treatment	4
Protein sustained release from isobutyramide-grafted stellate mesoporous silica nanoparticles	3
Antibiotic-loaded hydroxyapatite scaffolds fabricated from Nile tilapia bones for orthopaedics	3
Batch versus continuous blending of binary and ternary pharmaceutical powder mixtures	3
Atorvastatin-loaded emulsomes foam as a topical antifungal formulation	3
Integrating pressure sensor control into semi-solid extrusion 3D printing to optimize medicine manufacturing	3
End-point determination of heterogeneous formulations using inline torque measurements for a high-shear wet granulation process	3
Impact of mucus modulation by N-acetylcysteine on nanoparticle toxicity	3
Determination of the physical state of a drug in amorphous solid dispersions using artificial neural networks and ATR-FTIR spectroscopy	3
End-to-end approach for the characterization and control of product-related impurities in T cell bispecific antibody preparations	3
Downstream processing of spray-dried ASD with hypromellose acetate succinate – Roller compaction and subsequent compression into high ASD load tablets	3
3D printed multi-drug-loaded suppositories for acute severe ulcerative colitis	3
The effect of mAb and excipient cryoconcentration on long-term frozen storage stability – part 2: Aggregate formation and oxidation	3
The effect of mAb and excipient cryoconcentration on long-term frozen storage stability – Part 1: Higher molecular weight species and subvisible particle formation	3
Tailored hyaluronic acid-based nanogels as theranostic boron delivery systems for boron neutron cancer therapy	3
Experimental determination of the velocity distribution in USP Apparatus 1 (basket apparatus) using Particle Image Velocimetry (PIV)	3
Investigating the role of excipients on the physical stability of directly compressed tablets	3
The effect of exhalation before the inhalation of dry powder aerosol drugs on the breathing parameters, emitted doses and aerosol size distributions	3
Drug crystal growth in ternary amorphous solid dispersions: Effect of surfactants and polymeric matrix-carriers	3
A case study on decentralized manufacturing of 3D printed medicines	3
Nanoparticles design considerations to co-deliver nucleic acids and anti-cancer drugs for chemoresistance reversal	3
3D printed matrix solid forms: Can the drug solubility and dose customisation affect their controlled release behaviour?	3
Continuous twin screw granulation: Impact of microcrystalline cellulose batch-to-batch variability during granulation and drying – A QbD approach	3
Influence of drug loading on the physical stability of phospholipid-stabilised colloidal lipid emulsions	3
A potent novel vaccine adjuvant based on straight polyacrylate	3

Oxidation of polysorbates – An underestimated degradation pathway?	3
Development and evaluation of a composite dosage form containing desmopressin acetate for buccal administration	3
In vitro and in vivo assessment of hydroxypropyl cellulose as functional additive for enabling formulations containing itraconazole	3
Silicone elastomer formulations for improved performance of a multipurpose vaginal ring releasing dapivirine and levonorgestrel	3
Influence of process and formulation parameters on the preparation of solid lipid nanoparticles by dual centrifugation	3
Formulation, optimization, in-vivo biodistribution studies and histopathological safety assessment of duloxetine HCl-loaded ultra-elastic nanovesicles for antidepressant effect after intranasal and tr	3
The shelf life of ASDs: 2. Predicting the shelf life at storage conditions	3
Enhanced stability and skin permeation of ibuprofen-loaded solid lipid nanoparticles based binary solid lipid matrix: Effect of surfactant and lipid compositions	2
Formulation and optimization of ivermectin nanocrystals for enhanced topical delivery	2
Formulation and evaluation of azithromycin-loaded silver nanoparticles for the treatment of infected wounds	2
The use of heat to deliver fentanyl via pulmonary drug delivery	2
The interplay of dissolution, solution crystallization and solid-state transformation of amorphous indomethacin in aqueous solution	2
The characteristics and biological activity enhancements of melatonin encapsulations for skin care product applications	2
Nanostructured N/S doped carbon dots/mesoporous silica nanoparticles and PVA composite hydrogel fabrication for anti-microbial and anti-biofilm application	2
The effect of excipient particle size on the reduction of compactibility after roller compaction	2
Identification of novel cyanoacrylate monomers for use in nanoparticle drug delivery systems prepared by miniemulsion polymerisation – A multistep screening approach	2
Tackling acne vulgaris by fabrication of tazarotene-loaded essential oil-based microemulsion: In vitro and in vivo evaluation	2
Inhalable aerosol microparticles with low carrier dosage and high fine particle fraction prepared by spray-freeze-drying	2
Preparation of chitosan-coated hollow tin dioxide nanoparticles and their application in improving the oral bioavailability of febuxostat	2
Dual-effects of caffeinated hyalurosomes as a nano-cosmeceutical gel counteracting UV-induced skin ageing	2
Noninvasive characterization (EPR, μCT, NMR) of 3D PLA electrospun fiber sponges for controlled drug delivery	2
Polymeric nanocomposite hydrogel scaffold for jawbone regeneration: The role of rosuvastatin calcium-loaded silica nanoparticles	2
Towards predicting the product quality in hot-melt extrusion: Small scale extrusion	2
Drop-on-powder 3D printing of amorphous high dose oral dosage forms: Process development, opportunities and printing limitations	2
The effect of lung emptying before the inhalation of aerosol drugs on drug deposition in the respiratory system	2
Towards better understanding of the influence of process parameters in roll compaction/dry granulation on throughput, ribbon microhardness and granule failure load	2
Investigation on the self-assembly of the NFL-TBS.40-63 peptide and its interaction with gold nanoparticles as a delivery agent for glioblastoma	2
Novel nasal niosomes loaded with lacosamide and coated with chitosan: A possible pathway to target the brain to control partial-onset seizures	2
The impact of solvent selection on the characteristics of niosome nanoparticles prepared by microfluidic mixing	2
Terahertz time-domain spectroscopy for powder compact porosity and pore shape measurements: An error analysis of the anisotropic bruggeman model	2
Ethoxy acetalated dextran nanoparticles for drug delivery: A comparative study of formulation methods	2
Dexamethasone-loaded cochlear implants: How to provide a desired “burst release”	2
WITHDRAWN: Specific protein-protein interactions limit the cutaneous iontophoretic transport of interferon beta-1B and a poly-ARG interferon beta-1B analogue	1
Preparation and in vitro evaluation of hot-melt extruded pectin-based pellets containing ketoprofen for colon targeting	1
A network of regulatory innovations to improve FDA quality assessments of human drug applications	1
Dual-targeting inhibition of TNFR1 for alleviating rheumatoid arthritis by a novel composite nucleic acid nanodrug	1
Sustained release of therapeutic gene by injectable hydrogel for hepatocellular carcinoma	1
Protein photodegradation in the visible range? Insights into protein photooxidation with respect to protein concentration	1
Processability of mesoporous materials in fused deposition modeling for drug delivery of a model thermolabile drug	1
Poly(pseudo)rotaxanes formed by mixed micelles and α-cyclodextrin enhance terbinafine nail permeation to deeper layers	1
Long term behavior of dexamethasone-loaded cochlear implants: In vitro & in vivo	1
Polymorphic transitions in flufenamic acid-trehalose composites	1
Effect of the amount of cationic lipid used to complex siRNA on the cytotoxicity and proinflammatory activity of siRNA-solid lipid nanoparticles	1
Oral etoposide and zosuquidar bioavailability in rats: Effect of co-administration and in vitro-in vivo correlation of P-glycoprotein inhibition	1
Characterization and quantification of the interaction between the NFL-TBS.40‐63 peptide and lipid nanocapsules	1
Impact of polymer chemistry on critical quality attributes of selective laser sintering 3D printed solid oral dosage forms	1
Therapeutic effects of electrospun chitosan nanofibers on animal skin wounds: A systematic review and meta-analysis	1
X-ray imaging: A potential enabler of automated particulate detection and cake-structure analysis in lyophilized products?	1
Nanomedicine-based disulfiram and metal ion co-delivery strategies for cancer treatment	1
The Dynamic Intestinal Absorption Model (Diamod®), an in vitro tool to study the interconnected kinetics of gastrointestinal solubility, supersaturation, precipitation, and intestinal permeation proce	1
At-line porosity sensing for non-destructive disintegration testing in immediate release tablets	1
A drug repurposing approach of Atorvastatin calcium for its antiproliferative activity for effective treatment of breast cancer: In vitro and in vivo assessment	1
Characterization of radicals in polysorbate 80 using electron paramagnetic resonance (EPR) spectroscopy and spin trapping	1
3D printing of amorphous solid dispersions: A comparison of fused deposition modeling and drop-on-powder printing	1
Nanoparticles from Gantrez-based conjugates for the oral delivery of camptothecin	1
Use of simulated vaginal and menstrual fluids to model in vivo discolouration of silicone elastomer vaginal rings	1
PK-PD Evaluation of Inhaled Microparticles loaded with Ciprofloxacin-Copper complex in a Rat Model of Chronic Pseudomonas aeruginosa Lung Infection.	1
The combined effect of permeation enhancement and proteolysis inhibition on the systemic exposure of orally administrated peptides: Salcaprozate sodium, soybean trypsin inhibitor, and teriparatide stu	1
Box Behnken optimization of cubosomes for enhancing the anticancer activity of metformin: Design, characterization, and in-vitro cell proliferation assay on MDA-MB-231 breast and LOVO colon cancer cel	1
Model-based optimization of the primary drying phase of oral lyophilizates	1
Chicken embryo model for in vivo acute toxicological and antitumor efficacy evaluation of lipid nanocarrier containing doxorubicin	1
Boost of solubility and supersaturation of celecoxib via synergistic interactions of methacrylic acid-ethyl acrylate copolymer (1:1) and hydroxypropyl cellulose in ternary amorphous solid dispersions	1
How bulk fluid renewal can affect in vitro drug release from PLGA implants: Importance of the experimental set-up	1
Corrigendum to ‘LC-MS metabolomics comparisons of cancer cell and macrophage responses to methotrexate and polymer-encapsulated methotrexate’ [International Journal of Pharmaceutics: X Volume 1 (2019)	1
Continuous direct compression: Development of an empirical predictive model and challenges regarding PAT implementation	1
Batch vs. continuous direct compression – a comparison of material processability and final tablet quality	1
Rationalized landscape on protein-based cancer nanomedicine: Recent progress and challenges	1