JHEP Reports

Papers
(The TQCC of JHEP Reports is 8. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)
ArticleCitations
Trans-splenic anterograde coil assisted transvenous obliteration versus retrograde transvenous obliteration: are we heading the right way?146
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Statins in MASLD: Challenges and Future113
Applications of the AI-Cirrhosis-ECG (ACE) score for improving prediction of decompensation and liver-related outcomes in cirrhosis: A multi-cohort study102
Associations between fruit and vegetable consumption and HCC occurrence in patients with liver cirrhosis101
Response to: McKiernan P, Bernabeu JQ, Girard M, et al. Opinion paper on the diagnosis and treatment of progressive familial intrahepatic cholestasis. JHEP Rep 2023; 6:10094999
Identifying emergency presentations of chronic liver disease using routinely collected administrative hospital data95
Induction of phospholipase A2 group 4C by HCV infection regulates lipid droplet formation88
Protective Role of Physical Activity Against HCC Risk in Type 2 Diabetes: Evidence and Public Health Perspectives73
Surveillance for hepatocellular carcinoma in patients with Primary Biliary Cholangitis: for all or just for some?71
Serum FGF21 as predictor of response to atezolizumab and bevacizumab in HCC66
Macrophage ATG16L1 promotes liver regeneration after partial hepatectomy65
Multicenter Evaluation of Abbreviated MRI and Ultrasound for Detecting Early-Stage Hepatocellular Carcinoma64
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Copyright and information54
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Caspases compromise SLU7 and UPF1 stability and NMD activity during hepatocarcinogenesis53
Social support and risk of mortality in cirrhosis: A cohort study50
Platelet-derived thrombospondin 1 promotes immune cell liver infiltration and exacerbates diet-induced steatohepatitis48
Copyright and information47
Prophylactic blood product transfusions in post-endoscopic band ligation bleeding – ‘tag in TEG’46
Sofosbuvir plus velpatasvir for 8 weeks in patients with acute hepatitis C: The HepNet acute HCV-V study45
A missense variant in human perilipin 2 (PLIN2 Ser251Pro) reduces hepatic steatosis in mice45
Reconsidering low HDL-cholesterol levels as a predictive factor for the development of hepatocellular carcinoma44
Molecular magnetic resonance imaging of liver inflammation using an oxidatively activated probe44
Copyright and information43
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Reply to: “Hepatic bile acid transport increases in the postprandial state: A functional 11C-CSar PET/CT study in healthy humans”42
Fructoholism in adults: The importance of personalised care in metabolic dysfunction-associated fatty liver disease41
Survival benefit from liver transplantation for patients with and without hepatocellular carcinoma40
The third year40
Comment on “Quality of life and unmet needs in patients with chronic liver disease: A mixed-method systematic review”39
Hyperammonaemia induces mitochondrial dysfunction and neuronal cell death39
Contents39
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Assessing the periprocedural magnitude of platelet count change in response to lusutrombopag34
Increased carbohydrate deficient transferrin: Whisky or candy?34
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Copyright and information34
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Circulating indian hedgehog is a marker of the hepatocyte-TAZ pathway in experimental NASH and is elevated in humans with NASH33
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Development and validation of a dynamic survival prediction model for patients with acute-on-chronic liver failure32
Hepatitis C virus replication requires integrity of mitochondria-associated ER membranes31
Human umbilical cord mesenchymal stem cell-derived exosomes ameliorate liver steatosis by promoting fatty acid oxidation and reducing fatty acid synthesis31
Predicting post-resection recurrence by integrating imaging-based surrogates of distinct vascular patterns of hepatocellular carcinoma31
Spatial immunophenotypes predict clinical outcome in intrahepatic cholangiocarcinoma30
Broad-spectrum activity of bulevirtide against clinical isolates of HDV and recombinant pan-genotypic combinations of HBV/HDV29
AlcoChange: A digital therapeutic for patients with alcohol-related liver disease29
A machine learning-based classification of adult-onset diabetes identifies patients at risk of liver-related complications29
Combined inhibition of bile salt synthesis and intestinal uptake reduces cholestatic liver damage and colonic bile salts in mice29
Sex differences in chronic liver disease and benign liver lesions29
Paediatric hepatocellular adenomas: Lessons from a systematic review of relevant literature28
High childhood serum triglyceride concentrations associate with hepatocellular adenoma development in patients with glycogen storage disease type Ia28
The potential of volatile organic compounds to diagnose primary sclerosing cholangitis28
Development of mutated β-catenin gene signature to identify CTNNB1 mutations from whole and spatial transcriptomic data in patients with HCC28
Immunomodulatory receptor VSIG4 is released during spontaneous bacterial peritonitis and predicts short-term mortality27
Circulating neutrophil anti-pathogen dysfunction in cirrhosis27
Assessing immunological and virological responses in the liver: Implications for the cure of chronic hepatitis B virus infection27
Reply to: “The clinical advantage of fixed 8-mm diameter VCX stents over underdilated VTS stents is not established in refractory ascites”27
Tenofovir use is associated with a decreased risk of hepatocellular carcinoma among men with HIV irrespective of coinfection status27
Genetic or pharmacological reduction of cholangiocyte senescence improves inflammation and fibrosis in the Mdr2 mouse26
A small animal model of chronic hepatitis E infection using immunocompromised rats26
Epigenetics of alcohol-related liver diseases26
Preclinical and clinical studies of immunotherapy for the treatment of cholangiocarcinoma26
Characterisation of forkhead box protein A3 as a key transcription factor for hepatocyte regeneration26
Liver stiffness measurement predicts clinical outcomes in autoimmune hepatitis25
Insulin resistance is an integral feature of MASLD even in the presence of PNPLA3 variants25
MELD 3.0 adequately predicts mortality and renal replacement therapy requirements in patients with alcohol-associated hepatitis25
Predicting overt hepatic encephalopathy after TIPS: Value of three minimal hepatic encephalopathy tests25
Trends in hepatocellular carcinoma stage by racial/ethnic group in the United States, 1992–201925
CDK4/6 inhibitor-induced liver injury: Clinical phenotypes and role of corticosteroid treatment25
Hepatic estrogen receptor alpha drives masculinization in post-menopausal women with metabolic dysfunction-associated steatotic liver disease24
Risk of hepatocellular carcinoma in Asian patients with primary biliary cholangitis: A nationwide and hospital cohort study24
Inevitability of disease recurrence after liver transplantation for NAFLD cirrhosis23
Odevixibat treatment in an adult patient with advanced icteric progressive cholestatic liver disease23
ZBTB20 regulates WNT/CTNNB1 signalling pathway by suppressing PPARG during hepatocellular carcinoma tumourigenesis23
External validation of the IAIHG autoimmune hepatitis response criteria in a multicentric real-world cohort23
Serum miRNA profiles are altered in patients with primary sclerosing cholangitis receiving high-dose ursodeoxycholic acid23
Editorial Board page22
AFP score and metroticket 2.0 perform similarly and could be used in a “within-ALL” clinical decision tool22
Introducing adjuvant-loaded particulate hepatitis B core antigen as an alternative therapeutic hepatitis B vaccine component22
Assessing the impact of COVID-19 on liver cancer management (CERO-19)22
Transcriptomic landscapes of effective and failed liver regeneration in humans22
Autophagy-mediated reduction of miR-345 contributes to hepatic cystogenesis in polycystic liver disease22
Heterogeneity in intrahepatic macrophage populations and druggable target expression in patients with steatotic liver disease-related fibrosis22
Liver transplant selection criteria and outcomes in critically ill patients with ACLF21
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ABCB4 variant is associated with hepatobiliary MR abnormalities in people with low-phospholipid-associated cholelithiasis syndrome21
Molecular epidemiology and clinical characteristics of hepatitis D virus infection in Canada20
Characterisation of hepatic lipid signature distributed across the liver zonation using mass spectrometry imaging20
Identification and characterisation of a rare MTTP variant underlying hereditary non-alcoholic fatty liver disease20
Elevated serum levels of glial fibrillary acidic protein are associated with covert hepatic encephalopathy in patients with cirrhosis20
Malignant transformation of hepatocellular adenoma20
External validation of LCR1-LCR2, a multivariable HCC risk calculator, in patients with chronic HCV20
Editorial Board page19
Erratum to “Opinion paper on the diagnosis and treatment of progressive familial intrahepatic cholestasis” [JHEP Reports 6 (2024) 100949]19
JMJD2D stabilises and cooperates with HBx protein to promote HBV transcription and replication19
Quantitative magnetic resonance cholangiopancreatography metrics are associated with disease severity and outcomes in people with primary sclerosing cholangitis19
Virological markers for clinical trials in chronic viral hepatitis19
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HCV microelimination in harm reduction centres has benefits beyond HCV cure but is hampered by high reinfection rates19
Gut dysbiosis as a driver in alcohol-induced liver injury19
Waiting list mortality and 5-year transplant survival benefit of patients with MASLD: An Italian liver transplant registry study19
Essential roles of B cell subsets in the progression of MASLD and HCC18
Editorial Board page18
Reply to: Modeling challenges of hepatitis D virus kinetics during bulevirtide-based therapy18
Liver transplantation for HBV-related liver disease: Impact of prophylaxis for HBV on HCC recurrence18
Lipid metabolism in MASLD and MASH: From mechanism to the clinic18
Changing epidemiology of hepatocellular carcinoma in the Mediterranean area: a challenge for surveillance?18
Hepatitis D virus infection triggers CXCL9-11 upregulation in hepatocytes and liver infiltration of CXCR3+ CD4 T cells18
Tumor organoids for primary liver cancers: A systematic review of current applications in diagnostics, disease modeling, and drug screening18
Prediction of long-term HBsAg seroclearance in HBeAg-negative chronic hepatitis B patients18
Molecular MRI of T-cell immune response to cryoablation in immunologically hot vs. cold hepatocellular carcinoma18
CRISPR/Cas9 gene therapy increases the risk of tumorigenesis in the mouse model of hereditary tyrosinemia type I17
Waiting time dictates impact of frailty: A Spanish multicenter prospective study17
Direct mechanical exposure initiates hepatocyte proliferation17
Loss of hepatic FTCD promotes lipid accumulation and hepatocarcinogenesis by upregulating PPARγ and SREBP217
Development and validation of circulating protein signatures as diagnostic biomarkers for biliary tract cancer17
Predicting liver ablation volumes with real-time MRI thermometry17
Environmental exposures are important risk factors for advanced liver fibrosis in African American adults17
Circulating complement factor H levels are associated with disease severity and relapse in autoimmune hepatitis17
Intrapancreatic fat deposition is unrelated to liver steatosis in metabolic dysfunction-associated steatotic liver disease17
Impact of ammonia levels on outcome in clinically stable outpatients with advanced chronic liver disease17
New targets for NAFLD16
Case-finding strategies in non-alcoholic fatty liver disease16
Association of per- and polyfluoroalkyl substance exposure with fatty liver disease risk in US adults16
The Weight of Choices: Prioritizing Lifestyle Over GLP-1 Receptor Agonist Therapy in Managing MASLD16
Mechanobiology of portal hypertension16
Metabolic dysfunction-associated fatty liver disease increases risk of adverse outcomes in patients with chronic hepatitis B15
Quantification of alcohol intake in patients with steatotic liver disease and excessive alcohol intake15
Liver fibrosis screening increases alcohol abstinence15
Prospective comparison of transient elastography, MRI and serum scores for grading steatosis and detecting non-alcoholic steatohepatitis in bariatric surgery candidates15
Burden of grade 3 or 4 liver injury associated with immune checkpoint inhibitors15
Transforming growth factor β latency: A mechanism of cytokine storage and signalling regulation in liver homeostasis and disease15
Hepatitis B virus enhancer 1 activates preS1 and preS2 promoters of integrated HBV DNA impairing HBsAg secretion15
Burden, risk factors, and outcomes of multidrug-resistant bacterial colonisation at multiple sites in patients with cirrhosis15
Vasoconstrictor antagonism improves functional and structural vascular alterations and liver damage in rats with early NAFLD15
Role of precipitants in transition of acute decompensation to acute-on-chronic liver failure in patients with HBV-related cirrhosis15
What to do about hepatocellular carcinoma: Recommendations for health authorities from the International Liver Cancer Association15
Lower pretreatment HBV DNA levels are associated with better off-treatment outcomes after nucleo(s)tide analogue withdrawal in patients with HBeAg-negative chronic hepatitis B: A multicentre cohort st14
Clinical pattern of checkpoint inhibitor-induced liver injury in a multicentre cohort14
Risk of further decompensation/mortality in patients with cirrhosis and ascites as the first single decompensation event14
Cognitive dysfunction in early experimental metabolic dysfunction-associated steatotic liver disease is associated with systemic inflammation and neuroinflammation14
Blueprint to hepatitis B elimination in China: A modelling analysis of clinical strategies14
International study on the outcome of locoregional therapy for liver transplant in hepatocellular carcinoma beyond Milan criteria14
Histological activity despite normal ALT and IgG serum levels in patients with autoimmune hepatitis and cirrhosis14
Genotype-phenotype relationships of truncating mutations, p.E297G and p.D482G in bile salt export pump deficiency14
Primary liver cancer in the UK: Incidence, incidence-based mortality, and survival by subtype, sex, and nation14
Emerging roles of circular RNAs in liver cancer14
Long-term results of mycophenolate mofetil vs. azathioprine use in individuals with autoimmune hepatitis14
The dual role of TIGIT in regulatory and effector T cells in chronic liver disease14
Human iPSC-derived hepatocyte system models cholestasis with tight junction protein 2 deficiency13
Antagonism between wild-type and mutant β-catenin controls hepatoblastoma differentiation via fascin-113
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Copyright and information13
Clinical establishment of a laboratory developed quantitative HDV PCR assay on the cobas6800 high-throughput system13
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Response to: “Anticoagulation is not associated with an increased risk of variceal bleeding under systemic therapy for advanced HCC”13
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A personalized approach for tumour biopsy in hepatocellular carcinoma13
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Blue-collar work is a risk factor for developing IgG4-related disease of the biliary tract and pancreas12
Reply to: “Comment on “Quality of life and unmet needs in patients with chronic liver disease: A mixed-method systematic review””12
Copyright and information12
Editorial Board page12
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Top level research in hepatology: COVID-19 and beyond12
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Deep Learning Empowered Gadolinium-Free Contrast-Enhanced Abbreviated MRI for Diagnosing Hepatocellular Carcinoma12
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Deep phenotyping of patients with MASLD upon high-intensity interval training11
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Recurrence of autoimmune hepatitis cholestatic variant syndromes after liver transplantation affects graft and patient survival.11
Arachidonic acid activates NLRP3 inflammasome in MDSCs via FATP2 to promote post-transplant tumour recurrence in steatotic liver grafts11
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Identification and clinical implications of endogenous retrovirus elements suppressed by SETDB1 in hepatocellular carcinoma11
Cirrhosis-related sarcopenia may not resolve after liver transplantation11
Diversity and inclusion in chronic hepatitis B randomised controlled trials: A systematic meta-epidemiological review11
Oncogenic role of PMEPA1 and its association with immune exhaustion and TGF-β activation in HCC11
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Placental growth factor modulates endothelial NO production and exacerbates experimental hepatopulmonary syndrome11
Human GM-CSF/IL-3 enhance tumor immune infiltration in humanized HCC patient-derived xenografts11
Proinflammatory Macrophages Release CXCL5 to Regulate T Cell Function and Limit Effects of αPD-1 in Steatosis-driven Liver Cancer11
Introduction to corrigendum to ‘Level of MFAP4 in ascites independently predicts 1-year transplant-free survival in patients with cirrhosis’ [JHEP Reports 3 (2021) 100287]10
Ketamine restriction correlates with reduced cholestatic liver injury and improved outcomes in critically ill patients with burn injury10
Copyright and information10
Reply to: “Challenges in the diagnosis and management of AIH-PBC syndrome”10
A novel in vitro system for simultaneous infections with Hepatitis B, C, D and E Viruses10
Dynamic evolution of the sofosbuvir-associated variant A1343V in HEV-infected patients under concomitant sofosbuvir-ribavirin treatment10
Copyright and information10
Fragility index of positive phase II and III randomised clinical trials of treatments for hepatocellular carcinoma (2002–2022)10
ALDH1L2 drives HCC progression through TAM polarization10
Decreased maximal cortisol secretion rate in patients with cirrhosis: Relation to disease severity10
Depressive symptoms after hepatitis C cure and socio-behavioral correlates in aging people living with HIV (ANRS CO13 HEPAVIH)10
Editorial Board page10
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Distinct virologic trajectories in chronic hepatitis B identify heterogeneity in response to nucleos(t)ide analogue therapy10
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HBV001: Phase I study evaluating the safety and immunogenicity of the therapeutic vaccine ChAdOx1-HBV10
Metabolomics biomarkers of hepatocellular carcinoma in a prospective cohort of patients with cirrhosis9
Defatting strategies in the current era of liver steatosis9
Pegbelfermin selectively reduces secondary bile acid concentrations in patients with non-alcoholic steatohepatitis9
Effect of Peg-IFN on the viral kinetics of patients with HDV infection treated with bulevirtide9
A human monoclonal antibody against HBsAg for the prevention and treatment of chronic HBV and HDV infection9
A novel therapeutic HBV vaccine candidate induces strong polyfunctional cytotoxic T cell responses in mice9
Patient and physician expectations regarding disease and treatment of advanced HCC: The prospective PERCEPTION1 study9
Hepatic decompensation is accelerated in patients with cirrhosis and alpha-1 antitrypsin Pi∗MZ genotype9
Reply to: “Does currently recommended maternal antiviral prophylaxis against mother-to-child transmission of hepatitis B virus require enhancement?”9
Characterization of the liver immune microenvironment in liver biopsies from patients with chronic HBV infection9
Platelet adhesion assessed by PFA-100 is not linked to progression of ACLD8
Maternal obesity increases the risk of hepatocellular carcinoma through the transmission of an altered gut microbiome8
Effect of pegbelfermin on NASH and fibrosis-related biomarkers and correlation with histological response in the FALCON 1 trial8
SARS-CoV-2 receptor ACE2 is upregulated by fatty acids in human MASH8
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Ductular reaction is a prognostic factor in primary biliary cholangitis8
Inhibition of phospholipase D1 ameliorates hepatocyte steatosis and non-alcoholic fatty liver disease8
Hepatopulmonary syndrome in patients with porto-sinusoidal vascular disorder: Characteristics and outcome8
A gut microbiota-independent mechanism shapes the bile acid pool in mice with MASH8
Molecular determinants within the C-termini of L-HDAg that regulate hepatitis D virus replication and assembly8
Hepatitis D virus infection: Pathophysiology, epidemiology and treatment. Report from the first international delta cure meeting 20228
Profiling circulating microRNAs in patients with cirrhosis and acute-on-chronic liver failure8
Reply to: “Ductular reaction is a prognostic factor in primary biliary cholangitis”8
Potential role of liver-resident CD3+ macrophages in HBV clearance in a mouse hepatitis B model8
Association of physical activity, including amount and maintenance, with the risk of HCC among patients with type 2 diabetes8
MZF1 promotes tumour progression and resistance to anti-PD-L1 antibody treatment in hepatocellular carcinoma8
Downregulation of hepatic METTL3 contributes to APAP-induced liver injury in mice8
Where are the children in national hepatitis C policies? A global review of national strategic plans and guidelines8
Cellular origins of regenerating liver and hepatocellular carcinoma8
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Integrated phenotyping of the anti-cancer immune response in HIV-associated hepatocellular carcinoma8
Aetiology of acute hepatitis of unknown in children, association with AAV2 and controversies8
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