OOIR: Observatory of International Research

Papers

(The H4-Index of iScience is 68. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
Mechanisms of typhoid toxin neutralization by antibodies targeting glycan receptor binding and nuclease subunits	355
Inflammation conditional genome editing mediated by the CRISPR-Cas9 system	195
CD168+ macrophages promote hepatocellular carcinoma tumor stemness and progression through TOP2A/β-catenin/YAP1 axis	188
Thermal acclimation uncovers a simple genetic basis of adaptation to high temperature in a cosmopolitan pest	177
Lifespan associations of resting-state brain functional networks with ADHD symptoms	175
Hydroxyapatite catalyzed hydrothermal liquefaction transforms food waste from an environmental liability to renewable fuel	170
Selective modulator of nuclear receptor PPARγ with reduced adipogenic potential ameliorates experimental nephrotic syndrome	156
Nuclear transfer improves the developmental potential of embryos derived from cytoplasmic deficient oocytes	152
Standardized two-step testing of antibody activity in COVID-19 convalescent plasma	139
IL-27 mediates immune response of pneumococcal vaccine SPY1 through Th17 and memory CD4+T cells	137
MOCSS: Multi-omics data clustering and cancer subtyping via shared and specific representation learning	135
Bacterial surface properties influence the activity of the TAT-RasGAP317-326 antimicrobial peptide	128
Semen promotes oocyte development in Sebastes schlegelii elucidating ovarian development dynamics in live-bearing fish	121
Network characterization linc1393 in the maintenance of pluripotency provides the principles for lncRNA targets prediction	115
Tendon-inspired anti-freezing tough gels	112
Targeting ITK signaling for T cell-mediated diseases	105
Replication fork blocking deficiency leads to a reduction of rDNA copy number in budding yeast	104
Microbiome depletion prior to repeat mild TBI differentially alters social deficits and prefrontal cortex plasticity in adolescent and adult rats	99
Chemical inhibition of phosphatidylcholine biogenesis reveals its role in mitochondrial division	99
Regulation of interstitial fluid flow in adventitia along vasculature by heartbeat and respiration	98
Bitter taste receptor T2R14-Gαi coupling mediates innate immune responses to microbial quorum sensing molecules in cystic fibrosis	98
Zinc finger protein 593 promotes breast cancer development by ensuring DNA damage repair and cell-cycle progression	96
Amitriptyline revitalizes ICB response via dually inhibiting Kyn/Indole and 5-HT pathways of tryptophan metabolism in ovarian cancer	96
Cellular resistance to an oncolytic virus is driven by chronic activation of innate immunity	96
Native T1 mapping-based radiomics diagnosis of kidney function and renal fibrosis in chronic kidney disease	95

Applications of single-cell technologies in drug discovery for tumor treatment	94
Type I interferon regulation by USP18 is a key vulnerability in cancer	94
Transforming the CRISPR/dCas9-based gene regulation technique into a forward screening tool in Plasmodium falciparum	94
Mass burial genomics reveals outbreak of enteric paratyphoid fever in the Late Medieval trade city Lübeck	93
Early TRAIL-engagement elicits potent multimodal targeting of melanoma by CD34+ progenitor cell-derived NK cells	91
Sex differences in left-ventricular strain in a murine model of coxsackievirus B3 myocarditis	89
Exploring the substrate stereoselectivity and catalytic mechanism of nonribosomal peptide macrocyclization in surugamides biosynthesis	85
Activity-based protein profiling of human and plasmodium serine hydrolases and interrogation of potential antimalarial targets	85
Low levels of CIITA and high levels of SOCS1 predict COVID-19 disease severity in children and adults	84
Controllable preparation and performance of bio-based poly(lactic acid-iminodiacetic acid) as sustained-release Pb2+ chelating agent	83
The role of chirality and plastic crystallinity in the optical and mechanical properties of chlorosomes	82
The Prc and CtpA proteases modulate cell-surface signaling activity and virulence in Pseudomonas aeruginosa	81
Integrated edge information and pathway topology for drug-disease associations	80
Serum proteome profiling reveals heparanase as a candidate biomarker for chronic thromboembolic pulmonary hypertension	80
The implication of integrative multiple RNA modification-based subtypes in gastric cancer immunotherapy and prognosis	80
T cells with increased responsiveness cause obesity in mice without diet intervention	79
Matter-wave gap solitons and vortices in three-dimensional parity-time-symmetric optical lattices	79
Human iPS cells engender corneal epithelial stem cells with holoclone-forming capabilities	79
Changing the spin disorder of two-dimensional magnetic Cr2TiC2Tx to long-range order through noble metal adhesion	79
IGFBP2 derived from PO-MSCs promote epithelial barrier destruction by activating FAK signaling in nasal polyps	78
Low intensity transcranial ultrasound stimulation induces hemodynamic responses through neurovascular coupling	78
Microhabitat-specific diurnal metabolomic responses of the intertidal limpet Cellana toreuma to winter low temperature	76
Functional genomic analysis of Candida albicans protein kinases reveals modulators of morphogenesis in diverse environments	76
Neofunctionalization of ciliary BBS proteins to nuclear roles is likely a frequent innovation across eukaryotes	75
Inositol polyphosphate multikinase modulates redox signaling through nuclear factor erythroid 2-related factor 2 and glutathione metabolism	75
Thermal conductivity across transition metal dichalcogenide bilayers	75
Touching with the eyes: Oculomotor self-touch induces illusory body ownership	75
Risk of cerebrovascular disease after cancer diagnosis in the United States	74
Visual deprivation induces a stronger dive response in a harbor porpoise	72
Mitochondrial translation is the primary determinant of secondary mitochondrial complex I deficiencies	72
Some dogs can find the payoff-dominant outcome in the Assurance game	71
Evolution of zygomycete secretomes and the origins of terrestrial fungal ecologies	71
Spi1 R235C point mutation confers hypersensitivity to radiation-induced acute myeloid leukemia in mice	70
MIF-like domain containing protein orchestrates cellular differentiation and virulence in the fungal pathogen Magnaporthe oryzae	70
Single-cell immune profiling reveals broad anti-inflammation response in bipolar disorder patients with quetiapine and valproate treatment	69
Diminished representation of vitamin-B12-producing bacteria in constipated elders with frailty	69
Activity modulation of the Escherichia coli F1FO ATP synthase by a designed antimicrobial peptide via cardiolipin sequestering	69
Single cell sequencing maps skeletal muscle cellular diversity as disease severity increases in dystrophic mouse models	69
Exploring drought-responsive crucial genes in Sorghum	69
MYC dependency in GLS1 and NAMPT is a therapeutic vulnerability in multiple myeloma	68
PPARα and PPARγ activation is associated with pleural mesothelioma invasion but therapeutic inhibition is ineffective	68
Ion adsorption promotes Frank-van der Merwe growth of 2D transition metal tellurides	68
Cellular plasticity and immune microenvironment of malignant pleural effusion are associated with EGFR-TKI resistance in non–small-cell lung carcinoma	68
Adsorption and desorption behavior of Zn2+ in a flow-through electrosorption reactor	68