OOIR: Observatory of International Research

Papers

(The H4-Index of Life Science Alliance is 27. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 500 papers]. The publications cover those that have been published in the past four years, i.e., from 2019-10-01 to 2023-10-01.)

Article	Citations
TMPRSS2 and furin are both essential for proteolytic activation of SARS-CoV-2 in human airway cells	505
Caspase-1 interdomain linker cleavage is required for pyroptosis	74
USP30 sets a trigger threshold for PINK1–PARKIN amplification of mitochondrial ubiquitylation	61
Exosome-mediated delivery of CRISPR/Cas9 for targeting of oncogenic Kras^G12D in pancreatic cancer	61
Cx3cr1-deficient microglia exhibit a premature aging transcriptome	57
MMP9 modulates the metastatic cascade and immune landscape for breast cancer anti-metastatic therapy	55
A FIJI macro for quantifying pattern in extracellular matrix	55
Evaluation of colorectal cancer subtypes and cell lines using deep learning	55
A serum proteome signature to predict mortality in severe COVID-19 patients	53
Evaluating CRISPR-based prime editing for cancer modeling and CFTR repair in organoids	53
1,6-hexanediol rapidly immobilizes and condenses chromatin in living human cells	52
Caspase-1 cleaves Bid to release mitochondrial SMAC and drive secondary necrosis in the absence of GSDMD	52
Pancreatic cancer is marked by complement-high blood monocytes and tumor-associated macrophages	48
SARS-CoV-2 infection induces protective immunity and limits transmission in Syrian hamsters	44
Profiling of immune dysfunction in COVID-19 patients allows early prediction of disease progression	44
Robust production of uniform human cerebral organoids from pluripotent stem cells	43
SARM1 deficiency promotes rod and cone photoreceptor cell survival in a model of retinal degeneration	40
Refining the adipose progenitor cell landscape in healthy and obese visceral adipose tissue using single-cell gene expression profiling	39
Genome-wide R-loop analysis defines unique roles for DDX5, XRN2, and PRMT5 in DNA/RNA hybrid resolution	39
Metabolic reprogramming of fibro/adipogenic progenitors facilitates muscle regeneration	34
Virus-induced transposable element expression up-regulation in human and mouse host cells	34
IL-36 signaling in keratinocytes controls early IL-23 production in psoriasis-like dermatitis	33
GATA transcription factors, SOX17 and TFAP2C, drive the human germ-cell specification program	31
An extended DNA-free intranuclear compartment organizes centrosome microtubules in malaria parasites	30
MIC26 and MIC27 cooperate to regulate cardiolipin levels and the landscape of OXPHOS complexes	29

Oct4 mediates Müller glia reprogramming and cell cycle exit during retina regeneration in zebrafish	29
TspanC8 tetraspanins differentially regulate ADAM10 endocytosis and half-life	27
High levels of TFAM repress mammalian mitochondrial DNA transcription in vivo	27
Structural comparison of GLUT1 to GLUT3 reveal transport regulation mechanism in sugar porter family	27
The stress polarity signaling (SPS) pathway serves as a marker and a target in the leaky gut barrier: implications in aging and cancer	27
Keratinocyte interleukin-36 receptor expression orchestrates psoriasiform inflammation in mice	27