Circulation-Genomic and Precision Medicine

Papers
(The TQCC of Circulation-Genomic and Precision Medicine is 10. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-02-01 to 2024-02-01.)
ArticleCitations
Genetic Testing for Inherited Cardiovascular Diseases: A Scientific Statement From the American Heart Association192
International Evidence Based Reappraisal of Genes Associated With Arrhythmogenic Right Ventricular Cardiomyopathy Using the Clinical Genome Resource Framework103
Alcohol Consumption and Cardiovascular Disease93
Interleukin-6 Signaling Effects on Ischemic Stroke and Other Cardiovascular Outcomes75
Integrated Polygenic Tool Substantially Enhances Coronary Artery Disease Prediction66
Variant Interpretation for Dilated Cardiomyopathy61
Interactions Between Enhanced Polygenic Risk Scores and Lifestyle for Cardiovascular Disease, Diabetes, and Lipid Levels58
Polygenic Hyperlipidemias and Coronary Artery Disease Risk54
Noncoding RNAs in Cardiovascular Disease: Current Knowledge, Tools and Technologies for Investigation, and Future Directions: A Scientific Statement From the American Heart Association54
Implications of Genetic Testing in Dilated Cardiomyopathy50
Impact of Hormonal Therapies for Treatment of Hormone-Dependent Cancers (Breast and Prostate) on the Cardiovascular System: Effects and Modifications: A Scientific Statement From the American Heart As49
Genetic Testing for Heritable Cardiovascular Diseases in Pediatric Patients: A Scientific Statement From the American Heart Association43
How Communicating Polygenic and Clinical Risk for Atherosclerotic Cardiovascular Disease Impacts Health Behavior: an Observational Follow-up Study42
Spatial and Functional Distribution of MYBPC3 Pathogenic Variants and Clinical Outcomes in Patients With Hypertrophic Cardiomyopathy41
HeterozygousABCG5Gene Deficiency and Risk of Coronary Artery Disease41
Spontaneous Coronary Artery Dissection41
Transethnic Meta-Analysis of Genome-Wide Association Studies Identifies Three New Loci and Characterizes Population-Specific Differences for Coronary Artery Disease40
SCN5A Mutation Type and a Genetic Risk Score Associate Variably With Brugada Syndrome Phenotype in SCN5A Families39
Multiple Somatic Mutations for Clonal Hematopoiesis Are Associated With Increased Mortality in Patients With Chronic Heart Failure38
Metabolic Age Based on the BBMRI-NL 1 H-NMR Metabolomics Repository as Biomarker of Age-related Disease38
Prospective CYP2C19 Genotyping to Guide Antiplatelet Therapy Following Percutaneous Coronary Intervention38
Whole Blood DNA Methylation Signatures of Diet Are Associated With Cardiovascular Disease Risk Factors and All-Cause Mortality37
Polygenic Contribution to Low-Density Lipoprotein Cholesterol Levels and Cardiovascular Risk in Monogenic Familial Hypercholesterolemia32
Associations Between Female Sex, Sarcomere Variants, and Clinical Outcomes in Hypertrophic Cardiomyopathy32
Deep Mutational Scan of an SCN5A Voltage Sensor31
Reevaluation of the South Asian MYBPC3 Δ25bp Intronic Deletion in Hypertrophic Cardiomyopathy30
Genetic Testing for Diagnosis of Hypertrophic Cardiomyopathy Mimics28
De Novo Damaging Variants, Clinical Phenotypes, and Post-Operative Outcomes in Congenital Heart Disease27
Population Bias in Polygenic Risk Prediction Models for Coronary Artery Disease27
Clinical Profile of Cardiac Involvement in Danon Disease27
Pathogenic Variants Associated With Dilated Cardiomyopathy Predict Outcome in Pediatric Myocarditis26
Transethnic Transferability of a Genome-Wide Polygenic Score for Coronary Artery Disease23
Considerations for Cardiovascular Genetic and Genomic Research With Marginalized Racial and Ethnic Groups and Indigenous Peoples: A Scientific Statement From the American Heart Association23
Inherited Cardiomyopathies Revealed by Clinically Suspected Myocarditis23
Bayesian Inference Associates Rare KDR Variants With Specific Phenotypes in Pulmonary Arterial Hypertension22
Genetic Basis of Left Ventricular Noncompaction22
Genetic Association Between Hypoplastic Left Heart Syndrome and Cardiomyopathies22
Genome-Wide Association Study of Peripheral Artery Disease22
Cryptic Splice-Altering Variants in MYBPC3 Are a Prevalent Cause of Hypertrophic Cardiomyopathy21
Corrected QT Interval–Polygenic Risk Score and Its Contribution to Type 1, Type 2, and Type 3 Long-QT Syndrome in Probands and Genotype-Positive Family Members20
Promise and Potential Peril With Lumacaftor for the Trafficking Defective Type 2 Long-QT Syndrome-Causative Variants, p.G604S, p.N633S, and p.R685P, Using Patient-Specific Re-Engineered Cardiomyocytes20
Developing and Optimizing Innovative Tools to Address Familial Hypercholesterolemia Underdiagnosis20
Sexual Differences in Genetic Predisposition of Coronary Artery Disease20
Cadherin 2-Related Arrhythmogenic Cardiomyopathy20
Polygenic Risk Score for Low-Density Lipoprotein Cholesterol Is Associated With Risk of Ischemic Heart Disease and Enriches for Individuals With Familial Hypercholesterolemia19
Combining Clinical and Polygenic Risk Improves Stroke Prediction Among Individuals With Atrial Fibrillation18
Categorized Genetic Analysis in Childhood-Onset Cardiomyopathy18
Transcriptome Sequencing of Patients With Hypertrophic Cardiomyopathy Reveals Novel Splice-Altering Variants in MYBPC318
Association of Plasma Branched-Chain Amino Acid With Biomarkers of Inflammation and Lipid Metabolism in Women18
Prevalence and Outcomes of p.Val142Ile TTR Amyloidosis Cardiomyopathy: A Systematic Review18
Polygenic Risk Score for Coronary Artery Disease Improves the Prediction of Early-Onset Myocardial Infarction and Mortality in Men17
Prevalence and Disease Expression of Pathogenic and Likely Pathogenic Variants Associated With Inherited Cardiomyopathies in the General Population17
Genetic Studies of Hypertrophic Cardiomyopathy in Singaporeans Identify Variants in TNNI3 and TNNT2 That Are Common in Chinese Patients17
Associations of Genetically Predicted Lp(a) (Lipoprotein [a]) Levels With Cardiovascular Traits in Individuals of European and African Ancestry16
Predictive Accuracy of a Polygenic Risk Score for Postoperative Atrial Fibrillation After Cardiac Surgery16
Concordance of a High Polygenic Score Among Relatives15
Genetic Determinants of Electrocardiographic P-Wave Duration and Relation to Atrial Fibrillation15
Contribution of Noncanonical Splice Variants toTTNTruncating Variant Cardiomyopathy15
Genetic Risk Scores for Complex Disease Traits in Youth15
Exome Sequencing Highlights a Potential Role for Concealed Cardiomyopathies in Youthful Sudden Cardiac Death15
Exome Sequencing and Congenital Heart Disease in Sub-Saharan Africa15
Cardiac Imaging of Aortic Valve Area From 34 287 UK Biobank Participants Reveals Novel Genetic Associations and Shared Genetic Comorbidity With Multiple Disease Phenotypes14
Comprehensive Investigation of Circulating Biomarkers and Their Causal Role in Atherosclerosis-Related Risk Factors and Clinical Events14
Provocation Testing and Therapeutic Response in a Newly Described Channelopathy: RyR2 Calcium Release Deficiency Syndrome13
The Propagation of Racial Disparities in Cardiovascular Genomics Research13
Exploring the Genetic Architecture of Spontaneous Coronary Artery Dissection Using Whole-Genome Sequencing13
Impact of Genetic Variant Reassessment on the Diagnosis of Arrhythmogenic Right Ventricular Cardiomyopathy Based on the 2010 Task Force Criteria12
Genetically Determined Birthweight Associates With Atrial Fibrillation12
Recent Advances on the Genetics of Spontaneous Coronary Artery Dissection12
Predictive Accuracy of a Clinical and Genetic Risk Model for Atrial Fibrillation12
Clinical Genetic Risk Variants Inform a Functional Protein Interaction Network for Tetralogy of Fallot12
Polygenic Risk Score to Identify Subclinical Coronary Heart Disease Risk in Young Adults12
Clinical Findings and Diagnostic Yield of Arrhythmogenic Cardiomyopathy Through Genomic Screening of Pathogenic or Likely Pathogenic Desmosome Gene Variants12
Validation and Disease Risk Assessment of Previously Reported Genome-Wide Genetic Variants Associated With Brugada Syndrome12
Long-Term Follow-Up Study on the Uptake of Genetic Counseling and Predictive DNA Testing in Inherited Cardiac Conditions11
Prevalence of Pathogenic Variants in Cardiomyopathy-Associated Genes in Myocarditis11
Genetically Determined Serum Calcium Levels and Markers of Ventricular Repolarization: A Mendelian Randomization Study in the UK Biobank11
Conserved Role of the Large Conductance Calcium-Activated Potassium Channel, K Ca 1.1, in Sinus Node Function and Arrhythmia Risk11
Clinical Utility of a Phenotype-Enhanced MYH7 -Specific Variant Classification Framework in Hypertrophic Cardiomyopathy Genetic Testing11
Arrhythmic Phenotypes Are a Defining Feature of Dilated Cardiomyopathy-Associated SCN5A Variants: A Systematic Review11
Prognostic Value of a Polygenic Risk Score for Coronary Heart Disease in Individuals Aged 70 Years and Older11
Genotype-Guided Dosing of Warfarin in Chinese Adults11
Role of Rare and Low-Frequency Variants in Gene-Alcohol Interactions on Plasma Lipid Levels11
Evaluation of Clinical Practices Related to Variants of Uncertain Significance Results in Inherited Cardiac Arrhythmia and Inherited Cardiomyopathy Genes11
CELSR1 Risk Alleles in Familial Bicuspid Aortic Valve and Hypoplastic Left Heart Syndrome11
Characteristics of Cardiac Phenotype in Prenatal Familial Cases With NONO Mutations11
FADS1 (Fatty Acid Desaturase 1) Genotype Associates With Aortic Valve FADS mRNA Expression, Fatty Acid Content and Calcification10
Promise and Peril of Population Genomics for the Development of Genome-First Approaches in Mendelian Cardiovascular Disease10
Clinical Impact of Secondary Risk Factors in TTN -Mediated Dilated Cardiomyopathy10
Epigenetic Analyses of Human Left Atrial Tissue Identifies Gene Networks Underlying Atrial Fibrillation10
Revisiting the Diagnostic Yield of Hypertrophic Cardiomyopathy Genetic Testing10
Molecular Management of Multifocal Atrial Tachycardia in Noonan’s Syndrome With MEK1/2 Inhibitor Trametinib10
Integrative Prioritization of Causal Genes for Coronary Artery Disease10
Genetic Predictor to Identify Individuals With High Lipoprotein(a) Concentrations10
Lifelong Reduction in LDL (Low-Density Lipoprotein) Cholesterol due to a Gain-of-Function Mutation in LDLR10
Rare, Damaging DNA Variants in CORIN and Risk of Coronary Artery Disease: Insights From Functional Genomics and Large-Scale Sequencing Analyses10
Meta-Analysis of 26 638 Individuals Identifies Two Genetic Loci Associated With Left Ventricular Ejection Fraction10
Moving Genomics to Routine Care10
Variant Reinterpretation in Survivors of Cardiac Arrest With Preserved Ejection Fraction (the Cardiac Arrest Survivors With Preserved Ejection Fraction Registry) by Clinicians and Clinical Commercial 10
Estimating the Posttest Probability of Long QT Syndrome Diagnosis for Rare KCNH2 Variants10
Cost-Effectiveness of Polygenic Risk Scores to Guide Statin Therapy for Cardiovascular Disease Prevention10
Plasma Proteomic Profile Predicts Survival in Heart Failure With Reduced Ejection Fraction10
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