Circulation-Genomic and Precision Medicine

Papers
(The TQCC of Circulation-Genomic and Precision Medicine is 8. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-03-01 to 2025-03-01.)
ArticleCitations
MYH7 p.Glu903Gln Is a Pathogenic Variant Associated With Hypertrophic Cardiomyopathy133
Multiomic Profiling in Black and White Populations Reveals Novel Candidate Pathways in Left Ventricular Hypertrophy and Incident Heart Failure Specific to Black Adults94
Compound Heterozygous Truncating Variants in the BAG5 Gene As a Cause of Early-Onset Dilated Cardiomyopathy79
Retraction of: Systematic Evaluation of KCNQ1 variant using ACMG/AMP Guidelines and Risk Stratification in Long QT Syndrome Type 159
Pharmacogenomics of the Efficacy and Safety of Colchicine in COLCOT58
Pregnancy Outcomes in Females With Dilated Cardiomyopathy–Associated Rare Genetic Variants40
Oligogenic Architecture of Rare Noncoding Variants Distinguishes 4 Congenital Heart Disease Phenotypes39
Suppression and Replacement Gene Therapy for KCNH2 -Mediated Arrhythmias36
Clinical Characteristics of SCN5A p.R965C Carriers: A Common Founder Variant Predisposing to Brugada Syndrome in Thailand27
Genome-Wide De Novo Variants in Congenital Heart Disease Are Not Associated With Maternal Diabetes or Obesity27
Polygenic Risk and Coronary Artery Disease Severity25
How Normal Is Low-Normal Left Ventricular Ejection Fraction in Familial Dilated Cardiomyopathy?25
Variant Location Is a Novel Risk Factor for Individuals With Arrhythmogenic Cardiomyopathy Due to a Desmoplakin ( DSP ) Truncating Variant24
Reproductive Carrier Screening: Identifying Families at Risk for Familial Hypercholesterolemia in the United States23
Transcription Factors Leave Their Mark on the Heart22
Genetically Predicted Pulse Pressure and Risk of Abdominal Aortic Aneurysm: A Mendelian Randomization Analysis22
Mulibrey Nanism and the Real Time Use of Genome and Biobank Engines to Inform Clinical Care in an Ultrarare Disease22
Hidden Risk: Arrhythmogenic Genes in the General Population20
Investigation of Copy Number Variation in South African Patients With Congenital Heart Defects18
Lipoprotein(a) Atherosclerotic Cardiovascular Disease Risk Score Development and Prediction in Primary Prevention From Real-World Data18
Rare Genetic Variants Associated With Sudden Cardiac Arrest in the Young: A Prospective, Population-Based Study18
Dynamic Importance of Genomic and Clinical Risk for Coronary Artery Disease Over the Life Course18
Cardioinformatics Advancements in Healthcare and Biotechnology18
Correction to: Coassin et al, Genome-Wide Characterization of a Highly Penetrant Form of Hyperlipoprotein(a)emia Associated With Genetically Elevated Cardiovascular Risk18
Editorial Board18
CHDgene: A Curated Database for Congenital Heart Disease Genes17
Recent Advances on the Genetics of Spontaneous Coronary Artery Dissection17
System Genetics Including Causal Inference Identify Immune Targets for Coronary Artery Disease and the Lifespan17
Prognostic Implications Between hsCRP and CYP2C19 Genotype in Patients From East Asia: Insights From the PTRG-DES Consortium17
Plasma Proteomic Profile Predicts Survival in Heart Failure With Reduced Ejection Fraction17
Molecular Management of Multifocal Atrial Tachycardia in Noonan’s Syndrome With MEK1/2 Inhibitor Trametinib17
Soluble Urokinase Plasminogen Activator Receptor: Genetic Variation and Cardiovascular Disease Risk in Black Adults16
Development of a Patient-Specific p.D85N-Potassium Voltage-Gated Channel Subfamily E Member 1–Induced Pluripotent Stem Cell–Derived Cardiomyocyte Model for Drug-Induced Long QT Syndrome16
Novel SCN5A Variant Shows Multiple Phenotypic Expression in the Same Family16
Accelerated Epigenetic Aging Is Associated With Multiple Cardiometabolic, Hematologic, and Renal Abnormalities: A Project Baseline Health Substudy15
Clinical Implications of SCN10A Loss-of-Function Variants in 169 610 Exomes Representing the General Population15
Rapidly Progressive Peripheral Artery Disease: Importance of Oligogenic Inheritance and Functional Validation14
Life-Time Covariation of Major Cardiovascular Diseases14
Admixture Mapping of Chronic Kidney Disease and Risk Factors in Hispanic/Latino Individuals From Central America Country of Origin14
Integrating Clinical Phenotype With Multiomics Analyses of Human Cardiac Tissue Unveils Divergent Metabolic Remodeling in Genotype-Positive and Genotype-Negative Patients With Hypertrophic Cardiomyopa13
Polygenic Scoring for Detection of Ascending Thoracic Aortic Dilation13
Meta-Analysis of Genome-Wide Association Studies Reveals Genetic Mechanisms of Supraventricular Arrhythmias13
Phenotypic Spectrum of Subclinical Sarcomere-Related Hypertrophic Cardiomyopathy and Transition to Overt Disease13
Validation of a Polygenic Score for Beta-Blocker Survival Benefit in Patients With Heart Failure Using the United Kingdom Biobank13
Enhancing the Prediction Power of Polygenic Risk Scores in Genetically Diverse Coronary Heart Disease12
Heritability of Atrial Fibrillation Among Swedish Adoptees12
Long-Term Prevalence of Systolic Dysfunction in MYBPC3 Versus MYH7-Related Hypertrophic Cardiomyopathy12
Current State and Future of Polygenic Risk Scores in Cardiometabolic Disease: A Scoping Review12
Dilated Cardiomyopathy With Concomitant Salt-Losing Renal Tubulopathy Caused by Heterozygous RRAGD Gene Variant11
Sex-Specific Associations of Genetically Predicted Circulating Lp(a) (Lipoprotein(a)) and Hepatic LPA Gene Expression Levels With Cardiovascular Outcomes: Mendelian Rand11
Sugar-Sweetened Beverage Consumption May Modify Associations Between Genetic Variants in the CHREBP (Carbohydrate Responsive Element Binding Protein) Locus and HDL-C (High-Density Lipoprotein Choleste11
Multi-Ancestry Polygenic Risk Score for Coronary Heart Disease Based on an Ancestrally Diverse Genome-Wide Association Study and Population-Specific Optimization11
Role of TBX20 Truncating Variants in Dilated Cardiomyopathy and Left Ventricular Noncompaction10
Long-Read Sequence Confirmed a Large Deletion Including MYH6 and MYH7 in an Infant of Atrial Septal Defect and Atrial Arrhythmias10
DiscoVari : A Web-Based Precision Medicine Tool for Predicting Variant Pathogenicity in Cardiomyopathy- and Channelopathy-Associated Genes10
Rare, Damaging DNA Variants in CORIN and Risk of Coronary Artery Disease: Insights From Functional Genomics and Large-Scale Sequencing Analyses10
Is There a Role for Genetic Testing in Patients With Myocarditis?10
Genetic Effect on Body Mass Index and Cardiovascular Disease Across Generations10
Multi-Trait Genetic Analysis Reveals Clinically Interpretable Hypertension Subtypes10
Impact of Genetic Testing for Cardiomyopathy on Emotional Well-Being and Family Dynamics: A Study of Parents and Adolescents10
Metabolite Signature of Life’s Essential 8 and Risk of Coronary Heart Disease Among Low-Income Black and White Americans10
Homozygous SPEG Mutation Is Associated With Isolated Dilated Cardiomyopathy10
Clinical Outcomes and Genetic Analyses of Restrictive Cardiomyopathy in Children10
Genome-Wide Association and Inheritance-Based Analyses Implicate Unconventional Myosin Genes in Hypoplastic Left Heart Syndrome9
Sex-Specific Survival Bias and Interaction Modeling in Coronary Artery Disease Risk Prediction9
Cardiovascular Disease Knowledge Portal: A Community Resource for Cardiovascular Disease Research9
Incremental Value of a Metabolic Risk Score for Heart Failure Mortality: A Population-Based Study9
Cardiomyopathy Genes and Idiopathic VF: A Known Unknown?9
Prediction of Coronary Artery Disease and Major Adverse Cardiovascular Events Using Clinical and Genetic Risk Scores for Cardiovascular Risk Factors9
Genetic European Ancestry and Incident Diabetes in Black Individuals: Insights From the SPRINT Trial9
Low-Cost High-Throughput Genotyping for Diagnosing Familial Hypercholesterolemia9
The Genetic Basis of Primary Cardiomyopathies in Childhood: Implications for Clinical Genetic Testing9
Splicing Functional Assays Into the Genetic Testing Pipeline9
Mechanisms of RBM20 Cardiomyopathy: Insights From Model Systems9
Genetically Predicted Lipid Traits, Diabetes Liability, and Carotid Intima-Media Thickness in African Ancestry Individuals: A Mendelian Randomization Study9
Ultra-Rapid Nanopore Whole Genome Genetic Diagnosis of Dilated Cardiomyopathy in an Adolescent With Cardiogenic Shock9
Communal Coping as a Strategy to Enhance Family Engagement in Dilated Cardiomyopathy8
Causal Relationship Between Average Alcohol Consumption and Risk of Atrial Fibrillation: A Mendelian Randomization Study8
Risks of Ventricular Arrhythmia and Heart Failure in Carriers of RBM20 Variants8
Early Childhood-Onset Hypertrophic Cardiomyopathy in a Family With an In-Frame MYH7 Deletion8
Coronary Artery Disease Polygenic Risk Score Identifies Patients at Higher Risk for Recurrent Cardiovascular Events in the CANTOS Trial8
Genotype-Phenotype Taxonomy of Hypertrophic Cardiomyopathy8
Novel Insights Into DMD-Associated Dilated Cardiomyopathy8
Calmodulinopathy Associated Long QT Syndrome, Hypertrophic Cardiomyopathy With Excessive Trabeculation in a 14-Year-Old Girl Presenting With Ventricular Fibrillation8
Heterogeneity of the Predictive Polygenic Risk Scores for Coronary Heart Disease Age-at-Onset in Three Different Coronary Heart Disease Family-Based Ascertainments8
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