OOIR: Observatory of International Research

Papers

(The TQCC of CRISPR Journal is 8. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Inference of CRISPR Edits from Sanger Trace Data	312
CRISPRCasTyper: Automated Identification, Annotation, and Classification of CRISPR-Cas Loci	156
Deconvolution of Complex DNA Repair (DECODR): Establishing a Novel Deconvolution Algorithm for Comprehensive Analysis of CRISPR-Edited Sanger Sequencing Data	72
Rationally Designed Base Editors for Precise Editing of the Sickle Cell Disease Mutation	58
Genomic and Transcriptomic Analyses of Prime Editing Guide RNA–Independent Off-Target Effects by Prime Editors	37
Evaluation of Homology-Independent CRISPR-Cas9 Off-Target Assessment Methods	34
CRISPR-Cas12a Genome Editing at the Whole-Plant Level Using Two Compatible RNA Virus Vectors	32
Sensitive and Easy-Read CRISPR Strip for COVID-19 Rapid Point-of-Care Testing	31
ON-Target Adverse Events of CRISPR-Cas9 Nuclease: More Chaotic than Expected	30
Toward a CRISPR-Cas9-Based Gene Drive in the Diamondback Moth Plutella xylostella	30
CRISPR-Cas9 Gene Editing Protects from the A53T-SNCA Overexpression-Induced Pathology of Parkinson's Disease In Vivo	29
A Code of Ethics for Gene Drive Research	27
Adenine Base Editor Ribonucleoproteins Delivered by Lentivirus-Like Particles Show High On-Target Base Editing and Undetectable RNA Off-Target Activities	26
CRISPR-Cas9-Mediated Gene Editing of MYB28 Genes Impair Glucoraphanin Accumulation of Brassica oleracea in the Field	26
Genome Editing Using the CRISPR-Cas9 System to Generate a Solid-Red Germline of Nile Tilapia (Oreochromis niloticus)	25
Characterization of SHATTERPROOF Homoeologs and CRISPR-Cas9-Mediated Genome Editing Enhances Pod-Shattering Resistance in Brassica napus L.	24
CRISPR-Assisted DNA Detection: A Novel dCas9-Based DNA Detection Technique	23
Evolution of Type IV CRISPR-Cas Systems: Insights from CRISPR Loci in Integrative Conjugative Elements of Acidithiobacillia	23
Bacterial Retrons Enable Precise Gene Editing in Human Cells	23
Efficient Homology-Directed Repair with Circular Single-Stranded DNA Donors	23
CRISPR Arrays Away from cas Genes	22
Compact Cje3Cas9 for Efficient In Vivo Genome Editing and Adenine Base Editing	20
Insertion of the Icelandic Mutation (A673T) by Prime Editing: A Potential Preventive Treatment for Familial and Sporadic Alzheimer's Disease	19
CRISPR-Mediated Synergistic Epigenetic and Transcriptional Control	19
Heritable Human Genome Editing: The Public Engagement Imperative	18

Optimizing Integration and Expression of Transgenic Bruton's Tyrosine Kinase for CRISPR-Cas9-Mediated Gene Editing of X-Linked Agammaglobulinemia	18
Recent Advances in CRISPR-Based Biosensors for Point-of-Care Pathogen Detection	18
High-Throughput Imaging of CRISPR- and Recombinant Adeno-Associated Virus–Induced DNA Damage Response in Human Hematopoietic Stem and Progenitor Cells	18
The Transposon-Encoded Protein TnpB Processes Its Own mRNA into ωRNA for Guided Nuclease Activity	17
CRISPR-Cas “Non-Target” Sites Inhibit On-Target Cutting Rates	17
Increasing the Targeting Scope of CRISPR Base Editing System Beyond NGG	16
Generation of Nonmosaic, Two-Pore Channel 2 Biallelic Knockout Pigs in One Generation by CRISPR-Cas9 Microinjection Before Oocyte Insemination	15
Strategies for Enhancing the Homology-Directed Repair Efficiency of CRISPR-Cas Systems	15
One-Step Homology Mediated CRISPR-Cas Editing in Zygotes for Generating Genome Edited Cattle	15
RNA-Responsive gRNAs for Controlling CRISPR Activity: Current Advances, Future Directions, and Potential Applications	15
CRISPRclassify: Repeat-Based Classification of CRISPR Loci	15
Evolutionary Biology and Gene Editing of Cat Allergen, Fel d 1	15
A Multiplexed Cas13-Based Assay with Point-of-Care Attributes for Simultaneous COVID-19 Diagnosis and Variant Surveillance	14
A Novel Set of Cas9 Fusion Proteins to Stimulate Homologous Recombination: Cas9-HRs	14
Temperature-Inducible Precision-Guided Sterile Insect Technique	14
Programming Cells by Multicopy Chromosomal Integration Using CRISPR-Associated Transposases	14
Genetically Encoded CRISPR Components Yield Efficient Gene Editing in the Invasive Pest Drosophila suzukii	13
Catalytically Enhanced Cas9 Through Directed Protein Evolution	13
Rational Engineering of CRISPR-Cas9 Nuclease to Attenuate Position-Dependent Off-Target Effects	12
Improving FnCas12a Genome Editing by Exonuclease Fusion	12
(Broken) Promises of Sustainable Food and Agriculture through New Biotechnologies: The CRISPR Case	12
Efficient C-to-G Base Editing with Improved Target Compatibility Using Engineered Deaminase–nCas9 Fusions	12
Development and Characterization of a Modular CRISPR and RNA Aptamer Mediated Base Editing System	11
CALITAS: A CRISPR-Cas-aware ALigner for In silico off-TArget Search	11
New Editing Tools for Gene Therapy in Inherited Retinal Dystrophies	11
Regenerating Urethral Striated Muscle by CRISPRi/dCas9-KRAB-Mediated Myostatin Silencing for Obesity-Associated Stress Urinary Incontinence	11
Generation of a Commercial-Scale Founder Population of Porcine Reproductive and Respiratory Syndrome Virus Resistant Pigs Using CRISPR-Cas	11
Lentiviral Capsid-Mediated Streptococcus pyogenes Cas9 Ribonucleoprotein Delivery for Efficient and Safe Multiplex Genome Editing	11
Application of CRISPR-Cas9 Editing for Virus Engineering and the Development of Recombinant Viral Vaccines	10
Rescue of STAT3 Function in Hyper-IgE Syndrome Using Adenine Base Editing	10
Regulatory Considerations for Clinical Trial Applications with CRISPR-Based Medicinal Products	10
AsCRISPR: A Web Server for Allele-Specific Single Guide RNA Design in Precision Medicine	10
The Cas9 Hammer—and Sickle: A Challenge for Genome Editors	10
Auditing the Editor: A Review of Key Translational Issues in Epigenetic Editing	10
Development of a Cas12a-Based Genome Editing Tool for Moderate Thermophiles	10
Increased Efficiency for Biallelic Mutations of theCCR5Gene by CRISPR-Cas9 Using Multiple Guide RNAs As a Novel Therapeutic Option for Human Immunodeficiency Virus	10
The DNA-Dialogue: A Broad Societal Dialogue About Human Germline Genome Editing in the Netherlands	10
Increasing Gene Editing Efficiency for CRISPR-Cas9 by Small RNAs in Pluripotent Stem Cells	9
RNA Binding Proteins As Regulators of Oxidative Stress Identified by a Targeted CRISPR-Cas9 Single Guide RNA Library	9
Efficient and Economical Targeted Insertion in Plant Genomes via Protoplast Regeneration	9
Electroporation-Mediated Delivery of Cas9 Ribonucleoproteins Results in High Levels of Gene Editing in Primary Hepatocytes	9
A Living Organism in your CRISPR Toolbox: Caenorhabditis elegans Is a Rapid and Efficient Model for Developing CRISPR-Cas Technologies	9
A Mutation-Agnostic Hematopoietic Stem Cell Gene Therapy for Metachromatic Leukodystrophy	9
Novel Type V-A CRISPR Effectors Are Active Nucleases with Expanded Targeting Capabilities	9
Fast and Efficient Generation of Isogenic Induced Pluripotent Stem Cell Lines Using Adenine Base Editing	8
Cas4–Cas1 Is a Protospacer Adjacent Motif–Processing Factor Mediating Half-Site Spacer Integration During CRISPR Adaptation	8
Allele-Specific Inactivation of an Autosomal Dominant Epidermolysis Bullosa Simplex Mutation Using CRISPR-Cas9	8
Evaluation of Gene Knockouts by CRISPR as Potential Targets for the Genetic Engineering of the Mosquito Culex quinquefasciatus	8
Diversification of the CRISPR Toolbox: Applications of CRISPR-Cas Systems Beyond Genome Editing	8
Natural Nucleoside Modifications in Guide RNAs Can Modulate the Activity of the CRISPR-Cas9 System In Vitro	8

A CRISPR-Cas9, Cre-lox, and Flp-FRT Cascade Strategy for the Precise and Efficient Integration of Exogenous DNA into Cellular Genomes	8
A Transient Expression System with Stably Integrated CRISPR-dCas9 Fusions for Regulation of Genes Involved in Immunoglobulin G Glycosylation	8
Identification and Evolution of Cas9 tracrRNAs	8