OOIR: Observatory of International Research

Papers

(The TQCC of CRISPR Journal is 8. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)

Article	Citations
CRISPR Comparison Toolkit: Rapid Identification, Visualization, and Analysis of CRISPR Array Diversity	534
Exploring the Cytoplasmic Retention of CRISPR-Cas9 in Eukaryotic Cells: The Role of Nuclear Localization Signals and Ribosomal Interactions	54
Hairpin Internal Nuclear Localization Signals in CRISPR-Cas9 Enhance Editing in Primary Human Lymphocytes	53
Increasing Genome Editing Efficiency of Cas9 Nucleases by the Simultaneous Use of Transcriptional Activators and Histone Acetyltransferase Activator	45
Gene Editing Corrects In Vitro a G > A GLB1 Transition from a GM1 Gangliosidosis Patient	43
Will Advances in Genetic Medicine Lessen the Need for Germline Modifications?	43
Adaptation by Type V-A and V-B CRISPR-Cas Systems Demonstrates Conserved Protospacer Selection Mechanisms Between Diverse CRISPR-Cas Types	43
Inference of CRISPR Edits from Sanger Trace Data	35
A Taxonomic and Phylogenetic Classification of Diverse Base Editors	34
Acknowledgment of Reviewers 2022	34
Opposing Human Genetic Engineering	33
Curing “GFP-itis” in Bacteria with Base Editors: Development of a Genome Editing Science Program Implemented with High School Biology Students	30
Novel CRISPR-Associated Gene-Editing Systems Discovered in Metagenomic Samples Enable Efficient and Specific Genome Engineering	30
Advances in Cas12a-Based Amplification-Free Nucleic Acid Detection	29
Generation of a Commercial-Scale Founder Population of Porcine Reproductive and Respiratory Syndrome Virus Resistant Pigs Using CRISPR-Cas	27
The Lexicon of CRISPR: When Is It Too Much?	26
Efficient Installation of Heterozygous Mutations in Human Pluripotent Stem Cells Using Prime Editing	24
Gene Editing and Rett Syndrome: Does It Make the Cut?	24
Increasing the Targeting Scope of CRISPR Base Editing System Beyond NGG	24
Early Detection of Wildlife Disease Pathogens Using CRISPR-Cas System Methods	22
Generation of Human Isogenic Induced Pluripotent Stem Cell Lines with CRISPR Prime Editing	21
Efficient Homology-Directed Repair with Circular Single-Stranded DNA Donors	20
Implementing CRISPR-Cas9 Yeast Practicals into Biology Curricula	19
Comprehensive Analysis of CRISPR-Cas9 Editing Outcomes in Yeast Xanthophyllomyces dendrorhous	18
CRISPR Crops and Sustainable Agriculture	17

The Roles and Responsibilities of Scientific Journals in Research Governance: Editorial Policymaking at Nature and Springer Nature (1995–2023)	17
Gene Editing in the Chagas Disease Vector Rhodnius prolixus by Cas9-Mediated ReMOT Control	16
Rational Engineering of CRISPR-Cas9 Nuclease to Attenuate Position-Dependent Off-Target Effects	16
CRISPR-Cas9 Single Nucleotide Editing of Tuberous Sclerosis Complex 2 Gene in Mesenchymal Stem Cells	16
dCas9 Tells Tales: Probing Gene Function and Transcription Regulation in Cancer	15
Automated Good Manufacturing Practice-Compatible CRISPR-Cas9 Editing of Hematopoietic Stem and Progenitor Cells for Clinical Treatment of β-Hemoglobinopathies	14
Institutional Bioethics: From Critical Interdisciplinarity to Cosmopolitanism	14
A Story of Perseverance: An Interview with Matthew Porteus	14
Widespread Impact of Natural Genetic Variations in CRISPR-Cas9 Outcomes	13
Engineering CjCas9 for Efficient Base Editing and Prime Editing	13
Engineered Antiviral Sensor Targets Infected Mosquitoes	13
Specific High-Sensitivity Enzymatic Reporter UnLOCKing-Mediated Detection of Oncogenic BCR::ABL1 and EGFR	12
Evolutionary Biology and Gene Editing of Cat Allergen, Fel d 1	12
CRISPR à la carte	12
CRISPR Rewrites the Future of Medicine	12
Combined Theoretical, Bioinformatic, and Biochemical Analyses of RNA Editing by Adenine Base Editors	12
Enhancements of the CRISPR-Cas System in the Silkworm Bombyx mori	11
Fanzors: Mysterious TnpB-Like Bacterial Transposon-Related RNA-Guided DNA Nucleases of Eukaryotes	11
Efficient CRISPR-Cas9-Mediated Genome Editing of the Cane Toad ( Rhinella marina )	11
Affordable Pricing of CRISPR Treatments is a Pressing Ethical Imperative	11
A PCR-Induced Mutagenesis-Restriction Fragment Length Polymorphism Method for the Detection of CRISPR-Induced Indels	10
CRISPR Momentum in the Clinic and the Field	10
A Multiplexed Cas13-Based Assay with Point-of-Care Attributes for Simultaneous COVID-19 Diagnosis and Variant Surveillance	10
A Fluorescent Reporter Mouse for In Vivo Assessment of Genome Editing with Diverse Cas Nucleases and Prime Editors	10
Genome Editing Therapy for the Blood: Ex Vivo Success and In Vivo Prospects	9
Bacterial Retrons Enable Precise Gene Editing in Human Cells	9
Rapid and Technically Simple Detection of SARS-CoV-2 Variants Using CRISPR Cas12 and Cas13	9
The CRISPR Revolution in the Drug Discovery Workflow: An Industry Perspective	9
Navigating Viral Space with CRISPR Technologies	9
A Protein-Cutting CRISPR Complex Caught in Action	9
Introducing Faith-Based Claims to Ethical Discourse on Scientific Matters	9
It's a Knockout for Cat Allergies?	9
Acknowledgment of Reviewers 2023	9
Cas12a-Capture: A Novel, Low-Cost, and Scalable Method for Targeted Sequencing	9
Warrior Spirit: An Interview with Victoria Gray, Sickle Cell Pioneer	9
CRISPR-Cas9-Mediated Correction of TSC2 Pathogenic Variants in iPSCs from Patients with Tuberous Sclerosis Complex Type 2	9
Five Years of Progress in CRISPR Clinical Trials (2019–2024)	8
Moving Therapeutic Genome Editing into Global Clinical Trials and Medicine	8
Rapid Variant Pathogenicity Analysis by CRISPR Activation of CRB1 Gene Expression in Patient-Derived Fibroblasts	8
The New Old Colonialism	8
CRISPR-Cas9 Gene Editing Protects from the A53T-SNCA Overexpression-Induced Pathology of Parkinson's Disease In Vivo	8
Trichostatin A for Efficient CRISPR-Cas9 Gene Editing of Human Pluripotent Stem Cells	8