OOIR: Observatory of International Research

Papers

(The TQCC of CRISPR Journal is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
Increasing Genome Editing Efficiency of Cas9 Nucleases by the Simultaneous Use of Transcriptional Activators and Histone Acetyltransferase Activator	47
CRISPR Comparison Toolkit: Rapid Identification, Visualization, and Analysis of CRISPR Array Diversity	37
Hairpin Internal Nuclear Localization Signals in CRISPR-Cas9 Enhance Editing in Primary Human Lymphocytes	36
Adaptation by Type V-A and V-B CRISPR-Cas Systems Demonstrates Conserved Protospacer Selection Mechanisms Between Diverse CRISPR-Cas Types	35
Will Advances in Genetic Medicine Lessen the Need for Germline Modifications?	33
Exploring the Cytoplasmic Retention of CRISPR-Cas9 in Eukaryotic Cells: The Role of Nuclear Localization Signals and Ribosomal Interactions	29
Subtypes of Type I-E CRISPR-Cas Systems Distribution in Human Escherichia coli Isolates from China	29
Gene Editing Corrects In Vitro a G > A GLB1 Transition from a GM1 Gangliosidosis Patient	28
Novel CRISPR-Associated Gene-Editing Systems Discovered in Metagenomic Samples Enable Efficient and Specific Genome Engineering	23
Opposing Human Genetic Engineering	23
The Lexicon of CRISPR: When Is It Too Much?	22
Acknowledgment of Reviewers 2022	20
Curing “GFP-itis” in Bacteria with Base Editors: Development of a Genome Editing Science Program Implemented with High School Biology Students	20
Advances in Cas12a-Based Amplification-Free Nucleic Acid Detection	18
Generation of a Commercial-Scale Founder Population of Porcine Reproductive and Respiratory Syndrome Virus Resistant Pigs Using CRISPR-Cas	18
Gene Editing and Rett Syndrome: Does It Make the Cut?	17
Early Detection of Wildlife Disease Pathogens Using CRISPR-Cas System Methods	16
Efficient Installation of Heterozygous Mutations in Human Pluripotent Stem Cells Using Prime Editing	16
CRISPR Crops and Sustainable Agriculture	15
Generation of Human Isogenic Induced Pluripotent Stem Cell Lines with CRISPR Prime Editing	15
Comprehensive Analysis of CRISPR-Cas9 Editing Outcomes in Yeast Xanthophyllomyces dendrorhous	15
Efficient Homology-Directed Repair with Circular Single-Stranded DNA Donors	14
The Roles and Responsibilities of Scientific Journals in Research Governance: Editorial Policymaking at Nature and Springer Nature (1995–2023)	14
CRISPR-Cas9 Single Nucleotide Editing of Tuberous Sclerosis Complex 2 Gene in Mesenchymal Stem Cells	13
Viability-Based Assessment Reveals True Efficiency of CRISPR-Cas9 Transfection Methods in Rabbit Spermatozoa	13

Engineered Antiviral Sensor Targets Infected Mosquitoes	13
A Story of Perseverance: An Interview with Matthew Porteus	12
Institutional Bioethics: From Critical Interdisciplinarity to Cosmopolitanism	12
Automated Good Manufacturing Practice-Compatible CRISPR-Cas9 Editing of Hematopoietic Stem and Progenitor Cells for Clinical Treatment of β-Hemoglobinopathies	12
Regulatory Support for CRISPR in Ag: A Timely EU-Turn	12
Widespread Impact of Natural Genetic Variations in CRISPR-Cas9 Outcomes	12
Gene Editing in the Chagas Disease Vector Rhodnius prolixus by Cas9-Mediated ReMOT Control	12
Specific High-Sensitivity Enzymatic Reporter UnLOCKing-Mediated Detection of Oncogenic BCR::ABL1 and EGFR	12
A PCR-Induced Mutagenesis-Restriction Fragment Length Polymorphism Method for the Detection of CRISPR-Induced Indels	11
Efficient CRISPR-Cas9-Mediated Genome Editing of the Cane Toad ( Rhinella marina )	11
dCas9 Tells Tales: Probing Gene Function and Transcription Regulation in Cancer	11
Fanzors: Mysterious TnpB-Like Bacterial Transposon-Related RNA-Guided DNA Nucleases of Eukaryotes	11
Enhancements of the CRISPR-Cas System in the Silkworm Bombyx mori	11
CRISPR Momentum in the Clinic and the Field	11
Engineering CjCas9 for Efficient Base Editing and Prime Editing	11
A Multiplexed Cas13-Based Assay with Point-of-Care Attributes for Simultaneous COVID-19 Diagnosis and Variant Surveillance	10
A Fluorescent Reporter Mouse for In Vivo Assessment of Genome Editing with Diverse Cas Nucleases and Prime Editors	10
Conditional Expression of Cas9 and dCas9 in Lucilia cuprina Reveals dCas9-Associated Lethality	10
Affordable Pricing of CRISPR Treatments is a Pressing Ethical Imperative	10
A Protein-Cutting CRISPR Complex Caught in Action	10
CRISPR-Cas9-Mediated Correction of TSC2 Pathogenic Variants in iPSCs from Patients with Tuberous Sclerosis Complex Type 2	9
Rapid and Technically Simple Detection of SARS-CoV-2 Variants Using CRISPR Cas12 and Cas13	9
Warrior Spirit: An Interview with Victoria Gray, Sickle Cell Pioneer	9
It's a Knockout for Cat Allergies?	9
The CRISPR Revolution in the Drug Discovery Workflow: An Industry Perspective	9
Cas12a-Capture: A Novel, Low-Cost, and Scalable Method for Targeted Sequencing	9
Navigating Viral Space with CRISPR Technologies	8
Acknowledgment of Reviewers 2023	8
Rapid Variant Pathogenicity Analysis by CRISPR Activation of CRB1 Gene Expression in Patient-Derived Fibroblasts	8
Introducing Faith-Based Claims to Ethical Discourse on Scientific Matters	8
CRISPR Medicine Needs Infrastructure, Not Just Innovation	7
Genome Editing Headwinds: Can CRISPR Stay on Target?	7
The New Old Colonialism	7
Five Years of Progress in CRISPR Clinical Trials (2019–2024)	7
Strategies for Interdisciplinary Human Gene Editing Research: Insights from a Swiss Project	7
Reduction of Pre-Existing Adaptive Immune Responses Against SaCas9 in Humans Using Epitope Mapping and Identification	7
Genome Editing Therapy for the Blood: Ex Vivo Success and In Vivo Prospects	7
Trichostatin A for Efficient CRISPR-Cas9 Gene Editing of Human Pluripotent Stem Cells	7