JOR Spine

Article	Citations
	122
Injection Volume Is a Better Predictor of Stiffness Restoration Than Injection Force in an In Vitro Study of Nucleus Augmentation of the Intervertebral Disc	86
Clinical efficacy and biomechanical analysis of a novel hollow pedicle screw combined with kyphoplasty for the treatment of Kümmell disease	58
Bone morphogenetic proteins, DNA methylation, and gut microbiota interaction in lumbar disc degeneration: A multi‐omics Mendelian randomization study	57
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Comparison of four in vitro test methods to assess nucleus pulposus replacement device expulsion risk	48
The effects of extracellular matrix‐degrading enzymes polymorphisms on intervertebral disc degeneration	41
The efficacy and safety of oral antibiotic treatment in patients with chronic low back pain and Modic changes: A systematic review and meta‐analysis	30
Tracing the disc: The novel qualitative morphometric MRI based disc degeneration classification system	30
Exploring the Biopsychosocial Impact of Chronic Low Back Pain in Workers Through Artificial Intelligence‐Driven Phenotyping	26
Feasibility of Physical Exam and Performance‐Based Tests in Individuals With Chronic Low Back Pain: A Descriptive Study	25
Correction to “Feasibility of Physical Exam and Performance‐Based Tests in Individuals With Chronic Low Back Pain: A Descriptive Study”	25
Explorative Study of Modulatory Effects of Notochordal Cell‐Derived Extracellular Vesicles on the IL‐1β‐Induced Catabolic Cascade in Nucleus Pulposus Cell Pellets and Explants	25
Advancing Basic and Preclinical Spine Research: Highlights From the ORS PSRS 7th International Spine Research Symposium	25
Can axial loading restore in vivo disc geometry, opening pressure, and T2 relaxation time?	24
Effect of cigarette smoke exposure and cessation on regional diffusion properties in rat intervertebral discs	23
TNFα Receptor 1 and Not Receptor 2 Affect Annulus Fibrosus and Nucleus Pulposus Response to Cytokine Challenge in a Rat Model	22
M1 macrophage‐derived oncostatin M induces osteogenic differentiation of ligamentum flavum cells through the JAK2/STAT3 pathway	21
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Apigetrin alleviates intervertebral disk degeneration by regulating nucleus pulposus cell autophagy	20
Paraspinal muscles in individuals undergoing surgery for lumbar spine pathology lack a myogenic response to an acute bout of resistance exercise	20
Repetitive strikes loading organ culture model to investigate the biological and biomechanical responses of the intervertebral disc	20
Exploring the therapeutic potential of puerarin on intervertebral disc degeneration by regulating apoptosis of nucleus pulposus cells	20
Larger Lumbar Vertebral Body Osteophyte Volume Is Associated With Older Age and a More Caudal Vertebral Level in Individuals With Chronic Low Back Pain	19
Beyond the Curve: The Muscle‐Specific Asymmetries of Adolescent Idiopathic Scoliosis	18

Recommendations for intervertebral disc notochordal cell investigation: From isolation to characterization	18
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Constitutive and conditional gene knockout mice for the study of intervertebral disc degeneration: Current status, decision considerations, and future possibilities	17
Advanced Glycation End Products Induce Caudal Disc Degeneration in Ovariectomized Female Rats	16
Three‐dimensional ultrasonography could be a potential non‐ionizing tool to evaluate vertebral rotation of subjects with adolescent idiopathic scoliosis	16
Rapamycin mitigates inflammation‐mediated disc matrix homeostatic imbalance by inhibiting mTORC1 and inducing autophagy through Akt activation	15
Analysis of Nicotine Toxicity and Mechanisms of Senescence in Nucleus Pulposus Cells Using Network Toxicology and Molecular Docking Technique	15
Understanding the Physiological Behavior of Disc Cells in an In Vitro Imitation of the Healthy and Degenerated Disc Niche	14
Evaluation of instrumentation and pedicle screw design for posterior lumbar fixation: A pre‐clinical in vivo/ex vivo ovine model	14
Deep learning‐based detection and classification of lumbar disc herniation on magnetic resonance images	14
The proteomic landscape of extracellular vesicles derived from human intervertebral disc cells	14
Static study and numerical simulation of the influence of cement distribution in the upper and lower adjacent vertebrae on sandwich vertebrae in osteoporotic patients: Finite element analysis	13
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Nonviral overexpression of Scleraxis or Mohawk drives reprogramming of degenerate human annulus fibrosus cells from a diseased to a healthy phenotype	13
Evaluation of Lumbar Intervertebral Disc and Facet Joint Degeneration Using Histogram Analysis of T2 and T2	13
Ovine model of congenital chest wall and spine deformity: From birth to 3 months follow‐up	13
Biomedical applications of silk and its role for intervertebral disc repair	13
Issue Information	13
Correction to “Development and validation of deep learning models for identifying the brand of pedicle screws on plain spine radiographs”	12
The Cross‐Sectional Areas and Anterior–Posterior Balance of the Cervical Paraspinal Muscles in Dropped Head Syndrome and Cervical Spondylotic Myelopathy: A Propensity Score‐Matched Analysis	12
Issue Information	12
How to improve the mechanical safety of a novel spinal implant while saving costs and time	12
Deep learning‐based structure segmentation and intramuscular fat annotation on lumbar magnetic resonance imaging	12
Single‐Cell Analysis Integrated With Machine Learning Elucidates the Mechanisms of Nucleus Pulposus Cells Apoptosis in Intervertebral Disc Degeneration and Therapeutic Interventions	12
Clinical implications of linking microstructure, spatial biochemical, spatial biomechanical, and radiological features in ligamentum flavum degeneration	12
Macrophage Changes and High‐Throughput Sequencing in Aging Mouse Intervertebral Disks	12
A Porcine Model of Intervertebral Disc Injury Recapitulates Human Discogenic Pain Via Notochordal Cell Loss and Pain‐Inducing Nucleus Pulposus Cell Emergence	12
Defining the Human Nucleus Pulposus Microenvironment and Its Impact on Cell Matrix Synthesis and Metabolic Activity	12
Molecular Subtypes and Immune Microenvironment Characterization of the Annulus Fibrosus in Intervertebral Disc Degeneration: Insights From Translation Factor‐Related Gene Analysis	11
Dynamic loading leads to increased metabolic activity and spatial redistribution of viable cell density in nucleus pulposus tissue	11
Secretome and Pathway Analysis of Stress Induced Disc Degeneration In Vitro	11
The effect of fatty infiltration, revision surgery, and sex on lumbar multifidus passive mechanical properties	11
Why clinical trials in disc regeneration strive to achieve completion: Insights from publication status and funding sources	11
Lumbopelvic Kinematics During Functional Tasks in a Chronic Low Back Pain Observational Cohort	11
The Helical Compliance Vector: Utility for Quantifying Spinal Mechanics	10
Associations between femoral 3D curvature and sagittal imbalance of spine	10
Diurnal Asymmetric Loading Modulates Cell Phenotype in Intervertebral Disc	10
Preclinical in vivo animal models of intervertebral disc degeneration. Part 1: A systematic review	10
MRI‐based degeneration grades for lumbar facet joints do not correlate with cartilage mechanics	10
Ruxolitinib Delays Nucleus Pulposus Cell Senescence in Rat Intervertebral Discs	10
Physiological and Anthropometric Factors Associated With Spine Loading Estimates From Imaging‐Based Subject‐Specific Musculoskeletal Models	9
Range of Motion and Neutral Zone of All Human Spinal Motion Segments: A Data Collection of 30 Years of In Vitro Experiments Performed Under Standardized Testing Conditions	9
Silibinin promotes healing in spinal cord injury through anti‐ferroptotic mechanisms	9
Biomechanical evaluation of a novel biomimetic artificial intervertebral disc in canine cervical cadaveric spines	9
Phase 1 evaluation of an elastomeric nucleus pulposus device as an option to augment disc at microdiscectomy: Experimental results from biomechanical and biocompatibility testing and first in human	9
Single‐Side Iatrogenic Pedicle Injury May Trigger an Increased Risk of Contralateral Screw Loosening: An In Silico Study	9
Enhancing Clinical Insights: New Radiographic Grading for Lumbar Facet Joint Degeneration, A Reliability Study	9
Complex Mechanical Loading and Pro‐Inflammatory Cytokines in Intervertebral Disc Degeneration	9
In‐Field Ecological Momentary Assessment From Wearable Motion Sensors and Self‐Report in a Chronic Low Back Pain Cohort	8
Analysis of the value of potential biomarker S100‐A8 protein in the diagnosis and pathogenesis of spinal tuberculosis	8

Phosphatidylethanolamine Protects Nucleus Pulposus Cells From Oxidative Stress‐Induced Cellular Senescence and Extracellular Matrix Degradation by Promoting Autophagy	8
Issue Information	8
The non‐causative role of abnormal serum uric acid in intervertebral disc degeneration: A Mendelian randomization study	8
Identifying critical modules and biomarkers of intervertebral disc degeneration by using weighted gene co‐expression network	8
Enzymatic Behavior of Condoliase in Porcine Nucleus Pulposus: Ex Vivo and In Vitro Assessment	8
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Finite element modeling to predict the influence of anatomic variation and implant placement on performance of biological intervertebral disc implants	8
Plasma Pro‐ and Anti‐Inflammatory Cytokines in an Observational Chronic Low Back Pain Cohort	8
Evidence for a Causal Association Between Human Cytomegalovirus Infection and Chronic Back Pain: A One‐Sample Mendelian Randomization Study	8
Exploring the Causal Relationship Between the Plasma Levels of MMP1 (Matrix Metalloproteinase‐1), MMP3, MMP7, MMP10, and MMP12 and Intervertebral	8
Unilateral Lumbo‐Pelvic Fixation for Denis Type I Unilateral Sacral Fracture: A Finite Element Analysis	7
A successful PSRS special issue and Spine across the globe	7
Differential efficacy of two small molecule PHLPP inhibitors to promote nucleus Pulposus cell health	7
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Is There a Positive or Negative Correlation Between Cervical Vertebral Bone Quality and Intervertebral Disc Degeneration by Pfirrmann Grading	7
Preclinical development and characterisation of PP353, a formulation of linezolid for intradiscal administration	7
An in vivo model of ligamentum flavum hypertrophy from early‐stage inflammation to fibrosis	7
Epidemiology of Modic changes in dogs: Prevalence, possible risk factors, and association with spinal phenotypes	7
Evaluating the causal effect of atherosclerosis on the risk of intervertebral disc degeneration	7
Ex Vivo and In Vitro Proteomic Approach to Elucidate the Relevance of IL‐4 and IL‐10 in Intervertebral Disc Pathophysiology	7
Transient Receptor Potential Vanilloid 4 Knockdown Decreases Extracellular Matrix Synthesis via Autophagy Suppression in the Rat Intervertebral Disc	7
Characterization of Ovine Intervertebral Disc Health Across the Lifespan: Relationships Between Quantitative MRI , Radiological, Histological, Bioche	6
Large Language Models in Preclinical Spine Research: A Scoping Review and Expert Perspective on Evidence‐Aware Experimental Workflows	6
Patients With Chronic Low Back Pain Without Advanced Disk Degeneration Exhibit Gut Microbiome Dysbiosis: Evidence From an Age‐, Sex‐, and BMI ‐Matche	6
Viscoelastic and Morphologic Changes in the Lumbar Intervertebral Discs of the 5xFAD Mouse Model of Alzheimer's Disease	6
Spatial and Diurnal Variations in Sodium Content Within Intervertebral Disc Tissue	6
Characterization and modulation of the pro‐inflammatory effects of immune cells in the canine intervertebral disk	6
Socioeconomic status, mental health, and nutrition are the principal traits for low back pain phenotyping: Data from the osteoarthritis initiative	6
Facet deflection and strain are dependent on axial compression and distraction in C5–C7 spinal segments under constrained flexion	6
Understanding the etiopathogenesis of lumbar intervertebral disc herniation: From clinical evidence to basic scientific research	6
Mechanical crosstalk between the intervertebral disc, facet joints, and vertebral endplate following acute disc injury in a rabbit model	6
Inactivation of Tnf‐α/Tnfr signaling attenuates progression of intervertebral disc degeneration in mice	6
Phosphorylated heat shock protein 27 improves the bone formation ability of osteoblasts and bone marrow stem cells from patients with adolescent idiopathic scoliosis	6
Pain behavior and phenotype in a modified anterior lumbar disc puncture mouse model	6
Threats and opportunities of using ChatGPT in scientific writing—The risk of getting spine less	6
Reduced Shear Modulus and Altered Lamellar Morphology of the Outer Annulus Fibrosus in Painful Intervertebral Disc Degeneration Compared With Tissue From Non‐Surgical Controls	6
MRI T2 Relaxation Time of the Intervertebral Disc: Repeatability, the Effect of Time of Day, and Unloaded Rest	6
Neural network segmentation of disc volume from magnetic resonance images and the effect of degeneration and spinal level	6
Demographic and Biomedical Characteristics of an Observational Cohort With Chronic Low Back Pain: A Descriptive Analysis	6
Intradiscal administration of autologous platelet‐rich plasma in patients with Modic type 1 associated low back pain: A prospective pilot study	6
Comprehensive Evaluation of Facet Joints Osteoarthritis Radiological Features on Lumbar CT : A Multitask Deep Learning Approach	6
An in‐depth analysis of the immunomodulatory mechanisms of intervertebral disc degeneration	6
Issue Information	5
Novel 3D printed lattice structure titanium cages evaluated in an ovine model of interbody fusion	5
Automatic grading of intervertebral disc degeneration in lumbar dog spines	5
Application and Validation of Semiautomatic Quantification of Immunohistochemically Stained Sections for Low Cellular Tissue Such as Intervertebral Disc Using QuPath	5
Transcriptome Data Combined With Mendelian Randomization Analysis Identifies Key Genes Associated With Mitochondria and Programmed Cell Death in Intervertebral Disc Degeneration	5
Pharmacokinetics of PP353, a formulation of linezolid for intervertebral disc administration, in patients with chronic low back pain and Modic change Type 1: A first‐in‐human, Phase 1b, ope	5
High‐Resolution 3‐Dimensional Micro‐ CT Imaging of Intervertebral Discs Using a Novel Contrast Agent	5
Bioinformatics‐based discovery of intervertebral disc degeneration biomarkers and immune‐inflammatory infiltrates	5
DeVa (Decay Variance): A Novel Score Calculated via Postprocessing the Changes in Signal Intensity of an Intervertebral Disc in a T2* Multi‐Echo Magnetic Resonance Image Can Quan	5
Non‐enzymatic glycation reduces glucose transport in the human cartilage endplate independently of matrix porosity or proteoglycan content	5
A missense GDF5 variant causes brachydactyly type A1	5
Flexible support material maintains disc height and supports the formation of hydrated tissue engineered intervertebral discs in vivo	4
E74‐like ETS transcription factor 3 expression and regulation in human intervertebral disc	4
Chondrodystrophic Dogs as a Preclinical Large Animal Model of Discogenic Back Pain	4
Semi‐Automated μCT ‐Based Modeling of Vertebral Bony Endplate Microporosity and Mechanical Properties: Linking Microstructure to Inferred Mechanical	4
Developmental morphogens direct human induced pluripotent stem cells toward an annulus fibrosus‐like cell phenotype	4
Biomolecular therapies for chronic discogenic low back pain: A narrative review	4
Mechanistic Interactions Driving Nucleus Pulposus Cell Senescence in Intervertebral Disc Degeneration: A Multi‐Axial Perspective of Mechanical, Immune, and Metabolic Pathways	4
In Vivo Measurements Reveal Increased Nucleus Pulposus Lactate and Oxygen Concentrations in a Goat Model of Intervertebral Disc Degeneration	4
An additively manufactured model for preclinical testing of cervical devices	4
Wharton's Jelly mesenchymal stromal cell‐derived extracellular vesicles promote nucleus pulposus cell anabolism in an in vitro 3D alginate‐bead cultu	4
Reliability of Ultrasonography to Assess Spinal Compression During Heavy Load Carriage	4
Intervertebral Disc Degeneration Mediates the Causal Effect of Genetically Predicted Diffuse Idiopathic Skeletal Hyperostosis on Spinal Stenosis: Evidence From a Mendelian Randomization Study	4
Collagen integrity of the annulus fibrosus in degenerative disc disease individuals quantified with collagen hybridizing peptide	4
Harmonization and standardization of nucleus pulposus cell extraction and culture methods	4
Short‐Term Dynamic Unloading of Bovine Tail Discs in Culture Partially Mitigates Induced Degeneration After One‐Strike Trigger	4
Diagnostic Features of Discogenic Low Back Pain: A Narrative Review and Suggested Areas for Future Research and Clinical Practice	4
Mechanosensitive Ion Channel PIEZO1 Suppresses BMP2 ‐Induced Ossification of the Annulus Fibrosus	4
Slow twitch paraspinal muscle dysregulation in adolescent idiopathic scoliosis exhibiting HIF‐2α misexpression	4
Combined Flexion, Torsion and Compression Drive Distinct Intervertebral Disc Failure Mechanisms Under Asymmetric, High‐Cycle Loading	4
The influence of ligament biomechanics on proximal junctional kyphosis and failure in patients with adult spinal deformity	4
An exploration of knowledge‐organizing technologies to advance transdisciplinary back pain research	4
Animal Models of Disc Degeneration Using Puncture Injury: A 20 Year Perspective	4
pH: A major player in degenerative intervertebral disks	4
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Ultrafine‐Grained Materials With Antibacterial Properties: A Novel Approach to Reducing Spinal Implant‐Associated Infections	3
Comparative Analysis of Dual‐ miRNA Mediated Stimulation of Nucleus Pulposus and Bone Marrow Derived Stem Cells for Intervertebral Disc Repair	3
Injury Induces More Severe Biomechanical Changes in Middle‐Aged and Geriatric Lumbar Spines in a Mouse Ex Vivo Model	3

The association between low virulence organisms in different locations and intervertebral disc structural failure: A meta‐analysis and systematic review	3
Complex In Vivo Motion of the Bovine Tail Provides Unique Insights Into Intervertebral Disc Adaptation	3
Issue Information	3
Effects of circulating inflammatory proteins on spinal degenerative diseases: Evidence from genetic correlations and Mendelian randomization study	3
A novel spine tester TO GO	3
Intervertebral Disc Proteoglycans: Multifunctional Tissue Stabilizing and Instructional Cell Regulatory Proteins That Control Tissue Homeostasis	3
Regenerative Potential of Extracellular Vesicles on Intervertebral Disc Degeneration: What is the EV‐idence ?	3
Automated magnetic resonance imaging‐based grading of the lumbar intervertebral disc and facet joints	3
Variations in ECM Topography, Fiber Alignment, Mechanical Stiffness, and Cellular Composition Between Ventral and Dorsal Ligamentum Flavum Layers: Insights Into Hypertrophy Pathogenesis	3
Issue Information	3
Thoracolumbar Biomechanical Analysis of Lenke Type 1 Adolescent Idiopathic Scoliosis Across Roussouly Classifications	3
A pilot study: Nano‐hydroxyapatite‐PEG/PLA containing low dose rhBMP2 stimulates proliferation and osteogenic differentiation of human bone marrow derived mesenchymal stem cells	3
Wharton's Jelly Mesenchymal Stromal Cell‐Derived Extracellular Vesicles Attenuate Intervertebral Disc Degeneration Under Inflammatory Stress in an In Vitro 3D	3
Transcriptomic profiling reveals key early response genes during GDF6 ‐mediated differentiation of human adipose‐derived stem cells to nucleus pulpos	3
Advancing basic and preclinical spine research: Highlights from the ORS PSRS 6th International Spine Research Symposium	3
Revealing the novel metabolism‐related genes in the ossification of the ligamentum flavum based on whole transcriptomic data	3
Diverse and multifunctional roles for perlecan (HSPG2) in repair of the intervertebral disc	3
Comparative Finite Element Analysis of Denosumab and Bazedoxifene on Pedicle Screw Stability in Osteoporotic Spines	3
Development and validation of deep learning models for identifying the brand of pedicle screws on plain spine radiographs	3
Correction to ‘Recommendations for intervertebral disc notochordal cell investigation: From isolation to characterization’	3
The influence of intervertebral disc overloading on nociceptor calcium flickering	3
A Conceptual Review of Naturally Occurring Toxins and Venoms as Peptide Blockers to Combat Chronic Low Back Pain	3
Controversies in spine research: Organ culture versus in vivo models for studies of the intervertebral disc	3
Advancing spinal research beyond COVID‐19	3
Improving how orthopedic journals report research outcomes based on sex and gender	3
Annulus Fibrosus Repair via Interpenetration of a Non‐Woven Scaffold Supports Tissue Integration and Prevents Re‐Herniation	3
Development of a mouse model of chronic ventral spinal cord compression: Neurobehavioral, radiological, and pathological changes	3
The potential effect of romosozumab on perioperative management for instrumentation surgery	3
Efficacy of using autologous cells with graft substitutes for spinal fusion surgery: A systematic review and meta‐analysis of clinical outcomes and imaging features	3
Assessment of Vertebral Bone Marrow Perfusion, Fat/Water Content, and Trabecular Bone Changes Using Multimodal MRI and Micro‐CT in a Rat Model of Chronic Kidney Disease	3
Targeting nucleus pulposus cell death in the treatment of intervertebral disc degeneration	3
Issue Information	3
Therapeutic Approaches for Enhancing Spinal Fusion in Low Back Pain: A Review With a Focus on the Elderly	3