OOIR: Observatory of International Research

Papers

(The TQCC of Cancer Communications is 16. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)

Article	Citations
	529
Issue Information	501
Issue Information	320
Kindlin‐1 drives early steps of breast cancer metastasis	302
Correction to “Improving antitumor immunity using antiangiogenic agents: Mechanistic insights, current progress, and clinical challenges”	229
Defining and tracing subtypes of patient‐derived xenograft models in pancreatic ductal adenocarcinoma	219
Loss of CDKN1B induces an age‐related clonal hematopoietic disorder via Notch2 activity dysregulation	218
Fascin lysine 471 acetylation cooperates with serine 39 phosphorylation to inhibit actin‐bundling activity and tumor metastasis in esophageal squamous cell carcinoma	204
Issue Information	194
	180
Nine‐fold variation of risk of advanced colorectal neoplasms according to smoking and polygenic risk score: Results from a cross‐sectional study in a large screening colonoscopy cohort	178
	173
Age‐specific effectiveness of primary human papillomavirus screening versus cytology in a cervical cancer screening program: a nationwide cross‐sectional study	160
Single‐cell transcriptomics and epigenomics point to CD58‐CD2 interaction in controlling primary melanoma growth and immunity	152
Combined local therapy and CAR‐GPC3 T‐cell therapy in advanced hepatocellular carcinoma: a proof‐of‐concept treatment strategy	143
Long‐term survival outcomes and immune checkpoint inhibitor retreatment in patients with advanced cervical cancer treated with camrelizumab plus apatinib in the phase II CLAP study	138
The Chinese Society of Clinical Oncology (CSCO): Clinical guidelines for the diagnosis and treatment of colorectal cancer, 2024 update	137
Current status and perspectives of esophageal cancer: a comprehensive review	130
Signaling pathways in cancer‐associated fibroblasts: recent advances and future perspectives	122
Research trends of cancer metabolism: analysis from a Chinese perspective	121
Issue Information	121
	118
p38γ and p38δ as biomarkers in the interplay of colon cancer and inflammatory bowel diseases	114
Efficacy and safety of first‐line sintilimab plus anlotinib versus chemotherapy for metastatic non‐small cell lung cancer: a phase II, open‐label, randomized controlled trial	110
Impact of pre‐existing cardiometabolic diseases on metastatic cancer stage at diagnosis: a prospective multinational cohort study	103

Validation of different personalized risk models of chemotherapy‐induced nausea and vomiting: results of a randomized, double‐blind, phase III trial of fosaprepitant for cancer patients treated with h	103
	102
Comparative single‐cell analysis of esophageal cancer subtypes reveals tumor microenvironment distinctions explaining varied immunotherapy responses	97
EXPRESSION OF CONCERN: Discovery of a Novel Viroid‐Like Circular RNA in Colorectal Cancer	95
Issue Information	89
Neoadjuvant chemoradiotherapy with capecitabine and irinotecan guided by UGT1A1 status in patients with locally advanced rectal cancer: 5‐year update of	81
A nanotherapeutic strategy to target drug‐tolerant cells and overcome EGFR tyrosine kinase inhibitor resistance in lung cancer	79
Partial hepatectomy versus interventional treatment in patients with hepatitis B virus‐related hepatocellular carcinoma and clinically significant portal hypertension: a randomized comparative clinica	77
Single‐cell transcriptomics provides insights into the origin and immune microenvironment of cervical precancerous lesions	70
Development and validation of an artificial intelligence model for predicting post‐transplant hepatocellular cancer recurrence	69
Residual circulating tumor DNA after adjuvant chemotherapy effectively predicts recurrence of stage II‐III gastric cancer	66
N ⁶ ‐methyladenosine‐regulated exosome biogenesis orchestrates an immunosuppressive pre‐metastatic niche in gastric cancer peritoneal metastas	64
Predictive power of tertiary lymphoid structure signature for neoadjuvant chemotherapy response and immunotherapy benefit in HER2‐negative breast cancer	63
HSF1 facilitates the multistep process of lymphatic metastasis in bladder cancer via a novel PRMT5‐WDR5‐dependent transcriptional program	61
Multifunctional inorganic nanomaterials for cancer photoimmunotherapy	59
Oral transforming growth factor‐beta receptor 1 inhibitor vactosertib promotes osteosarcoma regression by targeting tumor proliferation and enhancing anti‐tumor immunity	57
Nasopharyngeal carcinoma treatment paradigm after HK0501 – a potential way forward	57
Issue Information	56
	55
Association of previously irradiated stable brain metastases with outcomes of atezolizumab‐treated non‐small cell lung cancer: A pooled analysis of individual patient data from three randomized trials	54
Cover Image, Volume 45, Issue 6	54
	54
Acquired RD3 loss regulates immune surveillance in high‐risk and therapy defying progressive neuroblastoma	52
Cover Image, Volume 42, Issue 1	52
Impact of small molecule‐mediated inhibition of ammonia detoxification on lung malignancies and liver metabolism	50
Intercellular communications and metabolic reprogramming as new predictive markers for immunotherapy responses in gastric cancer	49
Comprehensive DSRCT multi‐omics analyses unveil CACNA2D2 as a diagnostic hallmark and super‐enhancer‐driven EWSR1::WT1 signature gene	48
FOXO1 or not FOXO1: that is the question	48
Targeting IL‐17A to manage immunotherapy‐induced toxicity in melanoma	46
Functions and clinical significance of mechanical tumor microenvironment: cancer cell sensing, mechanobiology and metastasis	46
Association between antipsychotic agents and risk of lung cancer: a nested case‐control study	45
Ubiquitination in cancer: mechanisms and therapeutic opportunities	45
A multimodal integrative approach to model transcriptional addiction of thyroid cancer on RUNX2	45
Harnessing chimeric antigen receptor macrophages against solid tumors	44
A strong internal promoter drives massive expression of YEATS‐domain devoid MLLT3 transcripts in HSC and most lethal AML	44
Novel molecular mechanisms of immune evasion in hepatocellular carcinoma: NSUN2‐mediated increase of SOAT2 RNA methylation	43
Incidence of and survival with bone and soft tissue sarcoma: A nation‐wide study over four decades	43
Antitumoral effects of cannabis in Notch1‐mutated T‐cell acute lymphoblastic leukemia	41
Issue Information	40
First‐line serplulimab plus chemotherapy in extensive‐stage small‐cell lung cancer: Updated results and biomarker analysis from the ASTRUM‐005 randomized clinical trial	40
Correction to: **ZNF582 hypermethylation promotes metastasis of nasopharyngeal carcinoma by regulating the transcription of adhesion molecules Nectin‐3 and NRXN3**	38
Low household income and income volatility increase risk of lung cancer: A nationwide retrospective cohort study	37
m⁶A‐modified EHD1 controls PD‐L1 endosomal trafficking to modulate immune evasion and immunotherapy responses in lung adenocarcinoma	36
Enhanced selection of people for lung cancer screening using AHRR (cg05575921) or F2RL3 (cg03636183) methylation as biological markers of smoking exposure	35
Correction to “Circulating tumor cells share RNA modules with early embryo trophectoderm and with metastatic cancer”	34
Transcriptomic analyses of localized prostate cancers of East Asian and North American men reveal race‐specific luminal‐basal and microenvironmental differences	34
Long‐term outcomes of intraoperative radiotherapy for early‐stage breast cancer in China: a multicenter real‐world study	33
Development of antibody‐drug conjugates in cancer: Overview and prospects	33
Breast cancer: an up‐to‐date review and future perspectives	32
An HGF‐dependent positive feedback loop between bladder cancer cells and fibroblasts mediates lymphangiogenesis and lymphatic metastasis	32

Genomic information of children with malignant brain tumors for the prediction of length of hospitalization	32
Inhibition of mTOR attenuates the initiation and progression of BRCA1‐associated mammary tumors	30
Genomic characterization reveals distinct mutation landscapes and therapeutic implications in neuroendocrine carcinomas of the gastrointestinal tract	30
4‐1BB transcriptomic expression patterns across malignancies: Implications for clinical trials of 4‐1BB agonists	30
circCAPRIN1 interacts with STAT2 to promote tumor progression and lipid synthesis via upregulating ACC1 expression in colorectal cancer	29
Gene expression profiling improves prognostication by nomogram in patients with soft‐tissue sarcomas	29
Breaking barriers: The cGAS‐STING pathway as a novel frontier in cancer immunotherapy	29
Long‐term antibiotic use and risk of hepatocellular carcinoma later in life: a nationwide cohort study of 9.8 million participants	29
Neuroinflammation drives apathy in cancer cachexia	29
Spatial metabolomics for evaluating response to neoadjuvant therapy in non‐small cell lung cancer patients	28
Issue Information	27
The E3 ubiquitin ligase HUWE1 acts through the N‐Myc‐DLL1‐NOTCH1 signaling axis to suppress glioblastoma progression	27
Issue Information	27
Cover Image, Volume 44, Issue 4	27
	27
Sunitinib in metastatic renal cell carcinoma: clinical outcomes across risk groups in a Turkish Oncology Group Kidney Cancer Consortium	27
N‐acetyltransferase 10 promotes colon cancer progression by inhibiting ferroptosis through N4‐acetylation and stabilization of ferroptosis suppressor protein 1 (FSP1) mRNA	27
Single‐cell and bulk transcriptomics identifies a tumor‐specific CD36⁺ cancer‐associated fibroblast subpopulation in colorectal cancer	27
Knowing nodal Rouviére: the power of human intelligence in toxicity reduction	27
Galectin 3‐binding protein (LGALS3BP) depletion attenuates hepatic fibrosis by reducing transforming growth factor‐β1 (TGF‐β1) availability and inhibits hepatocarcinogenesis	26
Combination of photodynamic therapy and stimulator of interferon genes (STING) agonist inhibits colorectal tumor growth and recurrence	26
Breaking barriers: Smart vaccine platforms for cancer immunomodulation	26
Lipid metabolism reprograming by SREBP1‐PCSK9 targeting sensitizes pancreatic cancer to immunochemotherapy	25
Enhancement of CAR‐T cell activity against cholangiocarcinoma by simultaneous knockdown of six inhibitory membrane proteins	25
Issue Information	25
Pancreatic cancer survival trends in the US from 2001 to 2014: a CONCORD‐3 study	25
DNA methylation signature predicts cancer response to demethylation agents from profiling diverse cancer cell lines	25
Effect of neutrophils on tumor immunity and immunotherapy resistance with underlying mechanisms	24
Issue Information	24
Tumor microenvironment signaling and therapeutics in cancer progression	24
Cover Image, Volume 43, Issue 6	24
Ex vivo STAT3 phosphorylation in circulating immune cells: a novel biomarker for early cancer diagnosis and response to anti‐PD‐1 therapy	23
Leptin‐mediated suppression of lipoprotein lipase cleavage enhances lipid uptake and facilitates lymph node metastasis in gastric cancer	22
Beyond success: unveiling the hidden potential of radiotherapy and immunotherapy in solid tumors	22
Targeting ferroptosis resistance resensitizes metastatic HR⁺HER2⁻ breast cancer cells to palbociclib‐hormone therapy	21
Advanced precision modeling reveals divergent responses of hepatocellular carcinoma to combinatorial immunotherapy	21
A single measurement of fecal hemoglobin concentration outperforms polygenic risk score in colorectal cancer risk assessment	21
	21
Single‐cell‐eQTL mapping in circulating immune cells reveals genetic regulation of response‐associated networks in lung cancer immunotherapy	21
	20
The regulatory roles and clinical significance of glycolysis in tumor	20
Perivascular localized cells commit erythropoiesis in PDGF‐B‐expressing solid tumors	20
Enhancing sensitivity of triple‐negative breast cancer to DNA‐damaging therapy through chemical inhibition of the m6A methyltransferase METTL3	20
Proteomic identification of new diagnostic biomarkers of early‐stage cutaneous mycosis fungoides	19
Infection complications in febrile chimeric antigen receptor (CAR)‐T recipients during the peri‐CAR‐T cell treatment period examined using metagenomic next‐generation sequencing (mNGS)	19
Real‐world outcomes of niraparib treatment in patients with ovarian cancer: a multicenter non‐interventional study in China	19
Issue Information	19
Safety and immunogenicity of a third dose of mRNA‐1273 vaccine among cancer patients	19
Tumor‐derived insulin‐like growth factor‐binding protein‐1 contributes to resistance of hepatocellular carcinoma to tyrosine kinase inhibitors	18
In vivo intratumoral heterogeneity in a dish: scalable forebrain organoid models of embryonal brain tumors for high‐throughput personalized drug discovery	17
The SARS‐CoV‐2 spike protein induces lung cancer migration and invasion in a TLR2‐dependent manner	17
Targeting N4‐acetylcytidine suppresses hepatocellular carcinoma progression by repressing eEF2‐mediated HMGB2 mRNA translation	17
Issue Information	17
HMGB3 promotes brain metastasis of lung adenocarcinoma by recruiting SSBP1 for nuclear translocation to remodel mitochondrial metabolism	17
Ferroptosis in cancer and cancer immunotherapy	17
Concurrent chemoradiotherapyof different radiation doses and different irradiation fields for locally advanced thoracic esophageal squamous cell carcinoma: A randomized, multicenter, phase III clinica	17
Evolution of tumor microenvironment in colorectal liver metastases under treatment stress	17
Lysosomal TMEM9‐LAMTOR4‐controlled mTOR signaling integrity is required for mammary tumorigenesis	17
Single‐cell atlas reveals a distinct immune profile fostered by T cell‐B cell crosstalk in triple negative breast cancer	17
Smoking, smoking cessation, and survival after cancer diagnosis in 128,423 patients across cancer types	16
Dlk1 is a novel adrenocortical stem/progenitor cell marker that predicts malignancy in adrenocortical carcinoma	16
Unraveling the routes to distant metastases in colorectal cancer: Tumor deposits and lymph node metastases as the gateway	16
NHE7 upregulation potentiates the uptake of small extracellular vesicles by enhancing maturation of macropinosomes in hepatocellular carcinoma	16
Discovery of a novel viroid‐like circular RNA in colorectal cancer	16