OOIR: Observatory of International Research

Papers

(The TQCC of Cancer Communications is 12. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
Issue Information	673
Age‐specific effectiveness of primary human papillomavirus screening versus cytology in a cervical cancer screening program: a nationwide cross‐sectional study	619
Issue Information	445
	392
Fascin lysine 471 acetylation cooperates with serine 39 phosphorylation to inhibit actin‐bundling activity and tumor metastasis in esophageal squamous cell carcinoma	346
Loss of CDKN1B induces an age‐related clonal hematopoietic disorder via Notch2 activity dysregulation	234
Long‐term survival outcomes and immune checkpoint inhibitor retreatment in patients with advanced cervical cancer treated with camrelizumab plus apatinib in the phase II CLAP study	211
Defining and tracing subtypes of patient‐derived xenograft models in pancreatic ductal adenocarcinoma	203
Current status and perspectives of esophageal cancer: a comprehensive review	194
Single‐cell transcriptomics and epigenomics point to CD58‐CD2 interaction in controlling primary melanoma growth and immunity	187
The Chinese Society of Clinical Oncology (CSCO): Clinical guidelines for the diagnosis and treatment of colorectal cancer, 2024 update	171
Kindlin‐1 drives early steps of breast cancer metastasis	167
	150
Nine‐fold variation of risk of advanced colorectal neoplasms according to smoking and polygenic risk score: Results from a cross‐sectional study in a large screening colonoscopy cohort	145
	130
Issue Information	127
Signaling pathways in cancer‐associated fibroblasts: recent advances and future perspectives	125
Combined local therapy and CAR‐GPC3 T‐cell therapy in advanced hepatocellular carcinoma: a proof‐of‐concept treatment strategy	119
Issue Information	118
Residual circulating tumor DNA after adjuvant chemotherapy effectively predicts recurrence of stage II‐III gastric cancer	117
Research trends of cancer metabolism: analysis from a Chinese perspective	114
Single‐cell transcriptomics provides insights into the origin and immune microenvironment of cervical precancerous lesions	111
Nasopharyngeal carcinoma treatment paradigm after HK0501 – a potential way forward	101
	95
Efficacy and safety of first‐line sintilimab plus anlotinib versus chemotherapy for metastatic non‐small cell lung cancer: a phase II, open‐label, randomized controlled trial	93

Impact of pre‐existing cardiometabolic diseases on metastatic cancer stage at diagnosis: a prospective multinational cohort study	89
Oral transforming growth factor‐beta receptor 1 inhibitor vactosertib promotes osteosarcoma regression by targeting tumor proliferation and enhancing anti‐tumor immunity	84
Combined treatment of non‐small cell lung cancer using radiotherapy and immunotherapy: challenges and updates	83
Validation of different personalized risk models of chemotherapy‐induced nausea and vomiting: results of a randomized, double‐blind, phase III trial of fosaprepitant for cancer patients treated with h	82
Partial hepatectomy versus interventional treatment in patients with hepatitis B virus‐related hepatocellular carcinoma and clinically significant portal hypertension: a randomized comparative clinica	78
Development and validation of an artificial intelligence model for predicting post‐transplant hepatocellular cancer recurrence	78
Predictive power of tertiary lymphoid structure signature for neoadjuvant chemotherapy response and immunotherapy benefit in HER2‐negative breast cancer	77
A nanotherapeutic strategy to target drug‐tolerant cells and overcome EGFR tyrosine kinase inhibitor resistance in lung cancer	77
p38γ and p38δ as biomarkers in the interplay of colon cancer and inflammatory bowel diseases	76
Intra‐heterogeneity in transcription and chemoresistant property of leukemia‐initiating cells in murine Setd2^−/− acute myeloid leukemia	69
P300/CBP‐associated factor (PCAF)‐mediated acetylation of Fascin at lysine 471 inhibits its actin‐bundling activity and tumor metastasis in esophageal cancer	69
Multifunctional inorganic nanomaterials for cancer photoimmunotherapy	66
HSF1 facilitates the multistep process of lymphatic metastasis in bladder cancer via a novel PRMT5‐WDR5‐dependent transcriptional program	65
The role of non‐coding RNAs in drug resistance of oral squamous cell carcinoma and therapeutic potential	64
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Issue Information	63
Novel molecular mechanisms of immune evasion in hepatocellular carcinoma: NSUN2‐mediated increase of SOAT2 RNA methylation	62
A strong internal promoter drives massive expression of YEATS‐domain devoid MLLT3 transcripts in HSC and most lethal AML	61
Acquired RD3 loss regulates immune surveillance in high‐risk and therapy defying progressive neuroblastoma	60
Incidence of and survival with bone and soft tissue sarcoma: A nation‐wide study over four decades	60
Cover Image, Volume 42, Issue 1	54
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A multimodal integrative approach to model transcriptional addiction of thyroid cancer on RUNX2	52
Impact of small molecule‐mediated inhibition of ammonia detoxification on lung malignancies and liver metabolism	52
Association of previously irradiated stable brain metastases with outcomes of atezolizumab‐treated non‐small cell lung cancer: A pooled analysis of individual patient data from three randomized trials	51
Association between antipsychotic agents and risk of lung cancer: a nested case‐control study	51
Intercellular communications and metabolic reprogramming as new predictive markers for immunotherapy responses in gastric cancer	49
Antitumoral effects of cannabis in Notch1‐mutated T‐cell acute lymphoblastic leukemia	44
FOXO1 or not FOXO1: that is the question	40
Targeting IL‐17A to manage immunotherapy‐induced toxicity in melanoma	40
Comprehensive DSRCT multi‐omics analyses unveil CACNA2D2 as a diagnostic hallmark and super‐enhancer‐driven EWSR1::WT1 signature gene	39
Programmed death ligand‐1 regulates angiogenesis and metastasis by participating in the c‐JUN/VEGFR2 signaling axis in ovarian cancer	38
Functions and clinical significance of mechanical tumor microenvironment: cancer cell sensing, mechanobiology and metastasis	38
Transcriptomic analyses of localized prostate cancers of East Asian and North American men reveal race‐specific luminal‐basal and microenvironmental differences	37
Cancer incidence, mortality, and burden in China: a time‐trend analysis and comparison with the United States and United Kingdom based on the global epidemiological data released in 2020	37
Correction to: **ZNF582 hypermethylation promotes metastasis of nasopharyngeal carcinoma by regulating the transcription of adhesion molecules Nectin‐3 and NRXN3**	37
Issue Information	36
Low household income and income volatility increase risk of lung cancer: A nationwide retrospective cohort study	35
Novel strategy for disease risk prediction incorporating predicted gene expression and DNA methylation data: a multi‐phased study of prostate cancer	35
Enhanced selection of people for lung cancer screening using AHRR (cg05575921) or F2RL3 (cg03636183) methylation as biological markers of smoking exposure	35
Development of antibody‐drug conjugates in cancer: Overview and prospects	34
Long‐term outcomes of intraoperative radiotherapy for early‐stage breast cancer in China: a multicenter real‐world study	34
Transcriptional suppression of CD8⁺ T cell exhaustion for improving T cell immunotherapy	33
An HGF‐dependent positive feedback loop between bladder cancer cells and fibroblasts mediates lymphangiogenesis and lymphatic metastasis	33
KDELR2 promotes breast cancer proliferation via HDAC3‐mediated cell cycle progression	33
Genomic information of children with malignant brain tumors for the prediction of length of hospitalization	31
Long‐term antibiotic use and risk of hepatocellular carcinoma later in life: a nationwide cohort study of 9.8 million participants	31
	31
Breast cancer: an up‐to‐date review and future perspectives	31
Spatial metabolomics for evaluating response to neoadjuvant therapy in non‐small cell lung cancer patients	29

Inhibition of mTOR attenuates the initiation and progression of BRCA1‐associated mammary tumors	28
Genomic characterization reveals distinct mutation landscapes and therapeutic implications in neuroendocrine carcinomas of the gastrointestinal tract	28
4‐1BB transcriptomic expression patterns across malignancies: Implications for clinical trials of 4‐1BB agonists	28
Artificial intelligence for assisting cancer diagnosis and treatment in the era of precision medicine	27
Gene expression profiling improves prognostication by nomogram in patients with soft‐tissue sarcomas	27
N⁶‐methyladenosine Steers RNA Metabolism and Regulation in Cancer	26
circCAPRIN1 interacts with STAT2 to promote tumor progression and lipid synthesis via upregulating ACC1 expression in colorectal cancer	26
N‐acetyltransferase 10 promotes colon cancer progression by inhibiting ferroptosis through N4‐acetylation and stabilization of ferroptosis suppressor protein 1 (FSP1) mRNA	26
JUPITER‐02 trial: advancing survival for recurrent metastatic nasopharyngeal carcinoma and next steps	26
YB1 regulates miR‐205/200b‐ZEB1 axis by inhibiting microRNA maturation in hepatocellular carcinoma	25
DNA methylation signature predicts cancer response to demethylation agents from profiling diverse cancer cell lines	25
Effect of neutrophils on tumor immunity and immunotherapy resistance with underlying mechanisms	25
Knowing nodal Rouviére: the power of human intelligence in toxicity reduction	24
Bevacizumab biosimilar LY01008 compared with bevacizumab (Avastin) as first‐line treatment for Chinese patients with unresectable, metastatic, or recurrent non‐squamous non–small‐cell lung cancer: A m	24
	23
Improved esophageal squamous cell carcinoma screening effectiveness by risk‐stratified endoscopic screening: evidence from high‐risk areas in China	23
Issue Information	23
Cover Image, Volume 44, Issue 4	23
Issue Information	23
The E3 ubiquitin ligase HUWE1 acts through the N‐Myc‐DLL1‐NOTCH1 signaling axis to suppress glioblastoma progression	23
Breaking barriers: Smart vaccine platforms for cancer immunomodulation	23
Identification of immune‐activating metabolite for enhancing T cell therapy of cancer	22
Single‐cell and bulk transcriptomics identifies a tumor‐specific CD36⁺ cancer‐associated fibroblast subpopulation in colorectal cancer	22
Combination of photodynamic therapy and stimulator of interferon genes (STING) agonist inhibits colorectal tumor growth and recurrence	22
Enhancement of CAR‐T cell activity against cholangiocarcinoma by simultaneous knockdown of six inhibitory membrane proteins	21
Pancreatic cancer survival trends in the US from 2001 to 2014: a CONCORD‐3 study	21
Galectin 3‐binding protein (LGALS3BP) depletion attenuates hepatic fibrosis by reducing transforming growth factor‐β1 (TGF‐β1) availability and inhibits hepatocarcinogenesis	21
Sunitinib in metastatic renal cell carcinoma: clinical outcomes across risk groups in a Turkish Oncology Group Kidney Cancer Consortium	21
Issue Information	20
Tumor microenvironment signaling and therapeutics in cancer progression	20
Advanced precision modeling reveals divergent responses of hepatocellular carcinoma to combinatorial immunotherapy	20
A single measurement of fecal hemoglobin concentration outperforms polygenic risk score in colorectal cancer risk assessment	20
A moonlighting function of choline kinase alpha 2 in the initiation of lipid droplet lipolysis in cancer cells	20
	19
Targeting ferroptosis resistance resensitizes metastatic HR⁺HER2⁻ breast cancer cells to palbociclib‐hormone therapy	19
Cover Image, Volume 43, Issue 6	19
Ex vivo STAT3 phosphorylation in circulating immune cells: a novel biomarker for early cancer diagnosis and response to anti‐PD‐1 therapy	19
The efficacy and possible mechanisms of immune checkpoint inhibitors in treating non‐small cell lung cancer patients with epidermal growth factor receptor mutation	18
The regulatory roles and clinical significance of glycolysis in tumor	18
Leptin‐mediated suppression of lipoprotein lipase cleavage enhances lipid uptake and facilitates lymph node metastasis in gastric cancer	18
Enhancing sensitivity of triple‐negative breast cancer to DNA‐damaging therapy through chemical inhibition of the m6A methyltransferase METTL3	17
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Evolution of tumor microenvironment in colorectal liver metastases under treatment stress	16
Beyond success: unveiling the hidden potential of radiotherapy and immunotherapy in solid tumors	16
Issue Information	16
Perivascular localized cells commit erythropoiesis in PDGF‐B‐expressing solid tumors	15
Concurrent chemoradiotherapyof different radiation doses and different irradiation fields for locally advanced thoracic esophageal squamous cell carcinoma: A randomized, multicenter, phase III clinica	15
Infection complications in febrile chimeric antigen receptor (CAR)‐T recipients during the peri‐CAR‐T cell treatment period examined using metagenomic next‐generation sequencing (mNGS)	15
Real‐world outcomes of niraparib treatment in patients with ovarian cancer: a multicenter non‐interventional study in China	15
Lysosomal TMEM9‐LAMTOR4‐controlled mTOR signaling integrity is required for mammary tumorigenesis	15
RGS12 inhibits the progression and metastasis of multiple myeloma by driving M1 macrophage polarization and activation in the bone marrow microenvironment	15
Safety and immunogenicity of a third dose of mRNA‐1273 vaccine among cancer patients	15
Proteomic identification of new diagnostic biomarkers of early‐stage cutaneous mycosis fungoides	15
Ferroptosis in cancer and cancer immunotherapy	14
The SARS‐CoV‐2 spike protein induces lung cancer migration and invasion in a TLR2‐dependent manner	14
Single‐cell atlas reveals a distinct immune profile fostered by T cell‐B cell crosstalk in triple negative breast cancer	14
Targeting N4‐acetylcytidine suppresses hepatocellular carcinoma progression by repressing eEF2‐mediated HMGB2 mRNA translation	14
Tumor‐derived insulin‐like growth factor‐binding protein‐1 contributes to resistance of hepatocellular carcinoma to tyrosine kinase inhibitors	14
Issue Information	13
NHE7 upregulation potentiates the uptake of small extracellular vesicles by enhancing maturation of macropinosomes in hepatocellular carcinoma	13
Efficacy, safety and biomarkers of SG001 for patients with previously treated recurrent or metastatic cervical cancer: an open‐label, multicenter, phase Ib trial	13
Cancer diagnosis is one quarter lower than the expected cancer incidence in the first year of COVID‐19 pandemic in Germany: A retrospective register‐based cohort study	13
Targeted STAT1 therapy for LZTR1‐driven peripheral nerve sheath tumor	13
Dlk1 is a novel adrenocortical stem/progenitor cell marker that predicts malignancy in adrenocortical carcinoma	13
	12
Diagnostic value of genetic mutation analysis and mutation profiling of cell‐free DNA in intraocular fluid for vitreoretinal lymphoma	12
Unraveling the routes to distant metastases in colorectal cancer: Tumor deposits and lymph node metastases as the gateway	12
Smoking, smoking cessation, and survival after cancer diagnosis in 128,423 patients across cancer types	12
Combination of anti‐PD‐L1 antibody with peptide MEL‐dKLA targeting M2 tumor‐associated macrophages suppresses breast cancer metastasis	12
Transient and DNA‐free in vivo CRISPR/Cas9 genome editing for flexible modeling of endometrial carcinogenesis	12
Discovery of a novel viroid‐like circular RNA in colorectal cancer	12
Issue Information	12