OOIR: Observatory of International Research

Papers

(The TQCC of Cancer Communications is 14. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)

Article	Citations
Issue Information	465
Issue Information	425
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Single‐cell transcriptomics and epigenomics point to CD58‐CD2 interaction in controlling primary melanoma growth and immunity	252
Issue Information	219
Nine‐fold variation of risk of advanced colorectal neoplasms according to smoking and polygenic risk score: Results from a cross‐sectional study in a large screening colonoscopy cohort	197
	180
Loss of CDKN1B induces an age‐related clonal hematopoietic disorder via Notch2 activity dysregulation	178
Fascin lysine 471 acetylation cooperates with serine 39 phosphorylation to inhibit actin‐bundling activity and tumor metastasis in esophageal squamous cell carcinoma	162
Defining and tracing subtypes of patient‐derived xenograft models in pancreatic ductal adenocarcinoma	161
Age‐specific effectiveness of primary human papillomavirus screening versus cytology in a cervical cancer screening program: a nationwide cross‐sectional study	156
Current status and perspectives of esophageal cancer: a comprehensive review	144
Kindlin‐1 drives early steps of breast cancer metastasis	143
Long‐term survival outcomes and immune checkpoint inhibitor retreatment in patients with advanced cervical cancer treated with camrelizumab plus apatinib in the phase II CLAP study	139
Combined local therapy and CAR‐GPC3 T‐cell therapy in advanced hepatocellular carcinoma: a proof‐of‐concept treatment strategy	137
The Chinese Society of Clinical Oncology (CSCO): Clinical guidelines for the diagnosis and treatment of colorectal cancer, 2024 update	133
Signaling pathways in cancer‐associated fibroblasts: recent advances and future perspectives	113
Issue Information	112
Partial hepatectomy versus interventional treatment in patients with hepatitis B virus‐related hepatocellular carcinoma and clinically significant portal hypertension: a randomized comparative clinica	111
Predictive power of tertiary lymphoid structure signature for neoadjuvant chemotherapy response and immunotherapy benefit in HER2‐negative breast cancer	106
P300/CBP‐associated factor (PCAF)‐mediated acetylation of Fascin at lysine 471 inhibits its actin‐bundling activity and tumor metastasis in esophageal cancer	106
Residual circulating tumor DNA after adjuvant chemotherapy effectively predicts recurrence of stage II‐III gastric cancer	104
Development and validation of an artificial intelligence model for predicting post‐transplant hepatocellular cancer recurrence	102
N⁶‐methyladenosine‐regulated exosome biogenesis orchestrates an immunosuppressive pre‐metastatic niche in gastric cancer peritoneal metastasis	101

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Validation of different personalized risk models of chemotherapy‐induced nausea and vomiting: results of a randomized, double‐blind, phase III trial of fosaprepitant for cancer patients treated with h	98
Nasopharyngeal carcinoma treatment paradigm after HK0501 – a potential way forward	93
HSF1 facilitates the multistep process of lymphatic metastasis in bladder cancer via a novel PRMT5‐WDR5‐dependent transcriptional program	93
p38γ and p38δ as biomarkers in the interplay of colon cancer and inflammatory bowel diseases	88
Impact of pre‐existing cardiometabolic diseases on metastatic cancer stage at diagnosis: a prospective multinational cohort study	83
Single‐cell transcriptomics provides insights into the origin and immune microenvironment of cervical precancerous lesions	80
Research trends of cancer metabolism: analysis from a Chinese perspective	80
Efficacy and safety of first‐line sintilimab plus anlotinib versus chemotherapy for metastatic non‐small cell lung cancer: a phase II, open‐label, randomized controlled trial	74
	73
Oral transforming growth factor‐beta receptor 1 inhibitor vactosertib promotes osteosarcoma regression by targeting tumor proliferation and enhancing anti‐tumor immunity	69
Comparative single‐cell analysis of esophageal cancer subtypes reveals tumor microenvironment distinctions explaining varied immunotherapy responses	68
Multifunctional inorganic nanomaterials for cancer photoimmunotherapy	65
Combined treatment of non‐small cell lung cancer using radiotherapy and immunotherapy: challenges and updates	61
Issue Information	59
A nanotherapeutic strategy to target drug‐tolerant cells and overcome EGFR tyrosine kinase inhibitor resistance in lung cancer	59
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Cover Image, Volume 45, Issue 6	51
A multimodal integrative approach to model transcriptional addiction of thyroid cancer on RUNX2	51
Ubiquitination in cancer: mechanisms and therapeutic opportunities	48
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Association of previously irradiated stable brain metastases with outcomes of atezolizumab‐treated non‐small cell lung cancer: A pooled analysis of individual patient data from three randomized trials	47
FOXO1 or not FOXO1: that is the question	45
Cover Image, Volume 42, Issue 1	45
Targeting IL‐17A to manage immunotherapy‐induced toxicity in melanoma	44
Impact of small molecule‐mediated inhibition of ammonia detoxification on lung malignancies and liver metabolism	44
Antitumoral effects of cannabis in Notch1‐mutated T‐cell acute lymphoblastic leukemia	43
Comprehensive DSRCT multi‐omics analyses unveil CACNA2D2 as a diagnostic hallmark and super‐enhancer‐driven EWSR1::WT1 signature gene	43
Intercellular communications and metabolic reprogramming as new predictive markers for immunotherapy responses in gastric cancer	43
Incidence of and survival with bone and soft tissue sarcoma: A nation‐wide study over four decades	43
First‐line serplulimab plus chemotherapy in extensive‐stage small‐cell lung cancer: Updated results and biomarker analysis from the ASTRUM‐005 randomized clinical trial	42
A strong internal promoter drives massive expression of YEATS‐domain devoid MLLT3 transcripts in HSC and most lethal AML	39
Association between antipsychotic agents and risk of lung cancer: a nested case‐control study	38
Novel molecular mechanisms of immune evasion in hepatocellular carcinoma: NSUN2‐mediated increase of SOAT2 RNA methylation	38
Harnessing chimeric antigen receptor macrophages against solid tumors	38
Acquired RD3 loss regulates immune surveillance in high‐risk and therapy defying progressive neuroblastoma	38
Functions and clinical significance of mechanical tumor microenvironment: cancer cell sensing, mechanobiology and metastasis	37
Correction to: **ZNF582 hypermethylation promotes metastasis of nasopharyngeal carcinoma by regulating the transcription of adhesion molecules Nectin‐3 and NRXN3**	36
Novel strategy for disease risk prediction incorporating predicted gene expression and DNA methylation data: a multi‐phased study of prostate cancer	35
Transcriptomic analyses of localized prostate cancers of East Asian and North American men reveal race‐specific luminal‐basal and microenvironmental differences	35
Issue Information	35
An HGF‐dependent positive feedback loop between bladder cancer cells and fibroblasts mediates lymphangiogenesis and lymphatic metastasis	35
Low household income and income volatility increase risk of lung cancer: A nationwide retrospective cohort study	31
Enhanced selection of people for lung cancer screening using AHRR (cg05575921) or F2RL3 (cg03636183) methylation as biological markers of smoking exposure	31
m⁶A‐modified EHD1 controls PD‐L1 endosomal trafficking to modulate immune evasion and immunotherapy responses in lung adenocarcinoma	30
Transcriptional suppression of CD8⁺ T cell exhaustion for improving T cell immunotherapy	30
Long‐term outcomes of intraoperative radiotherapy for early‐stage breast cancer in China: a multicenter real‐world study	30
Breast cancer: an up‐to‐date review and future perspectives	29
Development of antibody‐drug conjugates in cancer: Overview and prospects	29
Long‐term antibiotic use and risk of hepatocellular carcinoma later in life: a nationwide cohort study of 9.8 million participants	28

Genomic characterization reveals distinct mutation landscapes and therapeutic implications in neuroendocrine carcinomas of the gastrointestinal tract	28
circCAPRIN1 interacts with STAT2 to promote tumor progression and lipid synthesis via upregulating ACC1 expression in colorectal cancer	27
Neuroinflammation drives apathy in cancer cachexia	27
Genomic information of children with malignant brain tumors for the prediction of length of hospitalization	26
Inhibition of mTOR attenuates the initiation and progression of BRCA1‐associated mammary tumors	26
4‐1BB transcriptomic expression patterns across malignancies: Implications for clinical trials of 4‐1BB agonists	25
Spatial metabolomics for evaluating response to neoadjuvant therapy in non‐small cell lung cancer patients	25
N‐acetyltransferase 10 promotes colon cancer progression by inhibiting ferroptosis through N4‐acetylation and stabilization of ferroptosis suppressor protein 1 (FSP1) mRNA	25
JUPITER‐02 trial: advancing survival for recurrent metastatic nasopharyngeal carcinoma and next steps	25
Artificial intelligence for assisting cancer diagnosis and treatment in the era of precision medicine	25
Gene expression profiling improves prognostication by nomogram in patients with soft‐tissue sarcomas	25
Lipid metabolism reprograming by SREBP1‐PCSK9 targeting sensitizes pancreatic cancer to immunochemotherapy	24
DNA methylation signature predicts cancer response to demethylation agents from profiling diverse cancer cell lines	24
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Issue Information	24
Issue Information	24
Pancreatic cancer survival trends in the US from 2001 to 2014: a CONCORD‐3 study	23
Knowing nodal Rouviére: the power of human intelligence in toxicity reduction	23
Sunitinib in metastatic renal cell carcinoma: clinical outcomes across risk groups in a Turkish Oncology Group Kidney Cancer Consortium	23
Single‐cell and bulk transcriptomics identifies a tumor‐specific CD36⁺ cancer‐associated fibroblast subpopulation in colorectal cancer	22
Galectin 3‐binding protein (LGALS3BP) depletion attenuates hepatic fibrosis by reducing transforming growth factor‐β1 (TGF‐β1) availability and inhibits hepatocarcinogenesis	22
Cover Image, Volume 44, Issue 4	21
The E3 ubiquitin ligase HUWE1 acts through the N‐Myc‐DLL1‐NOTCH1 signaling axis to suppress glioblastoma progression	21
Combination of photodynamic therapy and stimulator of interferon genes (STING) agonist inhibits colorectal tumor growth and recurrence	21
Breaking barriers: Smart vaccine platforms for cancer immunomodulation	21
Effect of neutrophils on tumor immunity and immunotherapy resistance with underlying mechanisms	20
Ex vivo STAT3 phosphorylation in circulating immune cells: a novel biomarker for early cancer diagnosis and response to anti‐PD‐1 therapy	20
Tumor microenvironment signaling and therapeutics in cancer progression	20
Issue Information	20
Enhancement of CAR‐T cell activity against cholangiocarcinoma by simultaneous knockdown of six inhibitory membrane proteins	20
Cover Image, Volume 43, Issue 6	20
Single‐cell‐eQTL mapping in circulating immune cells reveals genetic regulation of response‐associated networks in lung cancer immunotherapy	19
Advanced precision modeling reveals divergent responses of hepatocellular carcinoma to combinatorial immunotherapy	19
	19
A single measurement of fecal hemoglobin concentration outperforms polygenic risk score in colorectal cancer risk assessment	19
Targeting ferroptosis resistance resensitizes metastatic HR⁺HER2⁻ breast cancer cells to palbociclib‐hormone therapy	18
Beyond success: unveiling the hidden potential of radiotherapy and immunotherapy in solid tumors	18
The regulatory roles and clinical significance of glycolysis in tumor	18
The efficacy and possible mechanisms of immune checkpoint inhibitors in treating non‐small cell lung cancer patients with epidermal growth factor receptor mutation	18
Enhancing sensitivity of triple‐negative breast cancer to DNA‐damaging therapy through chemical inhibition of the m6A methyltransferase METTL3	18
Leptin‐mediated suppression of lipoprotein lipase cleavage enhances lipid uptake and facilitates lymph node metastasis in gastric cancer	17
RGS12 inhibits the progression and metastasis of multiple myeloma by driving M1 macrophage polarization and activation in the bone marrow microenvironment	17
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Evolution of tumor microenvironment in colorectal liver metastases under treatment stress	17
Issue Information	17
Infection complications in febrile chimeric antigen receptor (CAR)‐T recipients during the peri‐CAR‐T cell treatment period examined using metagenomic next‐generation sequencing (mNGS)	17
Proteomic identification of new diagnostic biomarkers of early‐stage cutaneous mycosis fungoides	16
Safety and immunogenicity of a third dose of mRNA‐1273 vaccine among cancer patients	16
Ferroptosis in cancer and cancer immunotherapy	16
Concurrent chemoradiotherapyof different radiation doses and different irradiation fields for locally advanced thoracic esophageal squamous cell carcinoma: A randomized, multicenter, phase III clinica	16
Lysosomal TMEM9‐LAMTOR4‐controlled mTOR signaling integrity is required for mammary tumorigenesis	16
Single‐cell atlas reveals a distinct immune profile fostered by T cell‐B cell crosstalk in triple negative breast cancer	16
The SARS‐CoV‐2 spike protein induces lung cancer migration and invasion in a TLR2‐dependent manner	16
Real‐world outcomes of niraparib treatment in patients with ovarian cancer: a multicenter non‐interventional study in China	16
Perivascular localized cells commit erythropoiesis in PDGF‐B‐expressing solid tumors	16
Targeting N4‐acetylcytidine suppresses hepatocellular carcinoma progression by repressing eEF2‐mediated HMGB2 mRNA translation	16
Tumor‐derived insulin‐like growth factor‐binding protein‐1 contributes to resistance of hepatocellular carcinoma to tyrosine kinase inhibitors	16
Issue Information	15
Issue Information	15
Dlk1 is a novel adrenocortical stem/progenitor cell marker that predicts malignancy in adrenocortical carcinoma	14
Unraveling the routes to distant metastases in colorectal cancer: Tumor deposits and lymph node metastases as the gateway	14
Diagnostic value of genetic mutation analysis and mutation profiling of cell‐free DNA in intraocular fluid for vitreoretinal lymphoma	14
Discovery of a novel viroid‐like circular RNA in colorectal cancer	14
ABTL0812 enhances antitumor effect of paclitaxel and reverts chemoresistance in triple‐negative breast cancer models	14
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Smoking, smoking cessation, and survival after cancer diagnosis in 128,423 patients across cancer types	14