Cancer Communications

Article	Citations
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Issue Information	501
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Kindlin‐1 drives early steps of breast cancer metastasis	302
Correction to “Improving antitumor immunity using antiangiogenic agents: Mechanistic insights, current progress, and clinical challenges”	229
Defining and tracing subtypes of patient‐derived xenograft models in pancreatic ductal adenocarcinoma	219
Loss of CDKN1B induces an age‐related clonal hematopoietic disorder via Notch2 activity dysregulation	218
Fascin lysine 471 acetylation cooperates with serine 39 phosphorylation to inhibit actin‐bundling activity and tumor metastasis in esophageal squamous cell carcinoma	204
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Nine‐fold variation of risk of advanced colorectal neoplasms according to smoking and polygenic risk score: Results from a cross‐sectional study in a large screening colonoscopy cohort	178
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Age‐specific effectiveness of primary human papillomavirus screening versus cytology in a cervical cancer screening program: a nationwide cross‐sectional study	160
Single‐cell transcriptomics and epigenomics point to CD58‐CD2 interaction in controlling primary melanoma growth and immunity	152
Combined local therapy and CAR‐GPC3 T‐cell therapy in advanced hepatocellular carcinoma: a proof‐of‐concept treatment strategy	143
Long‐term survival outcomes and immune checkpoint inhibitor retreatment in patients with advanced cervical cancer treated with camrelizumab plus apatinib in the phase II CLAP study	138
The Chinese Society of Clinical Oncology (CSCO): Clinical guidelines for the diagnosis and treatment of colorectal cancer, 2024 update	137
Current status and perspectives of esophageal cancer: a comprehensive review	130
Signaling pathways in cancer‐associated fibroblasts: recent advances and future perspectives	122
Research trends of cancer metabolism: analysis from a Chinese perspective	121
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p38γ and p38δ as biomarkers in the interplay of colon cancer and inflammatory bowel diseases	114
Efficacy and safety of first‐line sintilimab plus anlotinib versus chemotherapy for metastatic non‐small cell lung cancer: a phase II, open‐label, randomized controlled trial	110
Impact of pre‐existing cardiometabolic diseases on metastatic cancer stage at diagnosis: a prospective multinational cohort study	103

Validation of different personalized risk models of chemotherapy‐induced nausea and vomiting: results of a randomized, double‐blind, phase III trial of fosaprepitant for cancer patients treated with h	103
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Comparative single‐cell analysis of esophageal cancer subtypes reveals tumor microenvironment distinctions explaining varied immunotherapy responses	97
EXPRESSION OF CONCERN: Discovery of a Novel Viroid‐Like Circular RNA in Colorectal Cancer	95
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Neoadjuvant chemoradiotherapy with capecitabine and irinotecan guided by UGT1A1 status in patients with locally advanced rectal cancer: 5‐year update of	81
A nanotherapeutic strategy to target drug‐tolerant cells and overcome EGFR tyrosine kinase inhibitor resistance in lung cancer	79
Partial hepatectomy versus interventional treatment in patients with hepatitis B virus‐related hepatocellular carcinoma and clinically significant portal hypertension: a randomized comparative clinica	77
Single‐cell transcriptomics provides insights into the origin and immune microenvironment of cervical precancerous lesions	70
Development and validation of an artificial intelligence model for predicting post‐transplant hepatocellular cancer recurrence	69
Residual circulating tumor DNA after adjuvant chemotherapy effectively predicts recurrence of stage II‐III gastric cancer	66
N 6 ‐methyladenosine‐regulated exosome biogenesis orchestrates an immunosuppressive pre‐metastatic niche in gastric cancer peritoneal metastas	64
Predictive power of tertiary lymphoid structure signature for neoadjuvant chemotherapy response and immunotherapy benefit in HER2‐negative breast cancer	63
HSF1 facilitates the multistep process of lymphatic metastasis in bladder cancer via a novel PRMT5‐WDR5‐dependent transcriptional program	61
Multifunctional inorganic nanomaterials for cancer photoimmunotherapy	59
Oral transforming growth factor‐beta receptor 1 inhibitor vactosertib promotes osteosarcoma regression by targeting tumor proliferation and enhancing anti‐tumor immunity	57
Nasopharyngeal carcinoma treatment paradigm after HK0501 – a potential way forward	57
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Cover Image, Volume 45, Issue 6	54
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Association of previously irradiated stable brain metastases with outcomes of atezolizumab‐treated non‐small cell lung cancer: A pooled analysis of individual patient data from three randomized trials	54
Cover Image, Volume 42, Issue 1	52
Acquired RD3 loss regulates immune surveillance in high‐risk and therapy defying progressive neuroblastoma	52
Impact of small molecule‐mediated inhibition of ammonia detoxification on lung malignancies and liver metabolism	50
Intercellular communications and metabolic reprogramming as new predictive markers for immunotherapy responses in gastric cancer	49
Comprehensive DSRCT multi‐omics analyses unveil CACNA2D2 as a diagnostic hallmark and super‐enhancer‐driven EWSR1::WT1 signature gene	48
FOXO1 or not FOXO1: that is the question	48
Targeting IL‐17A to manage immunotherapy‐induced toxicity in melanoma	46
Functions and clinical significance of mechanical tumor microenvironment: cancer cell sensing, mechanobiology and metastasis	46
Association between antipsychotic agents and risk of lung cancer: a nested case‐control study	45
Ubiquitination in cancer: mechanisms and therapeutic opportunities	45
A multimodal integrative approach to model transcriptional addiction of thyroid cancer on RUNX2	45
Harnessing chimeric antigen receptor macrophages against solid tumors	44
A strong internal promoter drives massive expression of YEATS‐domain devoid MLLT3 transcripts in HSC and most lethal AML	44
Novel molecular mechanisms of immune evasion in hepatocellular carcinoma: NSUN2‐mediated increase of SOAT2 RNA methylation	43
Incidence of and survival with bone and soft tissue sarcoma: A nation‐wide study over four decades	43
Antitumoral effects of cannabis in Notch1‐mutated T‐cell acute lymphoblastic leukemia	41
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First‐line serplulimab plus chemotherapy in extensive‐stage small‐cell lung cancer: Updated results and biomarker analysis from the ASTRUM‐005 randomized clinical trial	40
Correction to: ZNF582 hypermethylation promotes metastasis of nasopharyngeal carcinoma by regulating the transcription of adhesion molecules Nectin‐3 and NRXN3	38
Low household income and income volatility increase risk of lung cancer: A nationwide retrospective cohort study	37
m6A‐modified EHD1 controls PD‐L1 endosomal trafficking to modulate immune evasion and immunotherapy responses in lung adenocarcinoma	36
Enhanced selection of people for lung cancer screening using AHRR (cg05575921) or F2RL3 (cg03636183) methylation as biological markers of smoking exposure	35
Correction to “Circulating tumor cells share RNA modules with early embryo trophectoderm and with metastatic cancer”	34
Transcriptomic analyses of localized prostate cancers of East Asian and North American men reveal race‐specific luminal‐basal and microenvironmental differences	34
Development of antibody‐drug conjugates in cancer: Overview and prospects	33
Long‐term outcomes of intraoperative radiotherapy for early‐stage breast cancer in China: a multicenter real‐world study	33
An HGF‐dependent positive feedback loop between bladder cancer cells and fibroblasts mediates lymphangiogenesis and lymphatic metastasis	32
Genomic information of children with malignant brain tumors for the prediction of length of hospitalization	32

Breast cancer: an up‐to‐date review and future perspectives	32
Genomic characterization reveals distinct mutation landscapes and therapeutic implications in neuroendocrine carcinomas of the gastrointestinal tract	30
4‐1BB transcriptomic expression patterns across malignancies: Implications for clinical trials of 4‐1BB agonists	30
Inhibition of mTOR attenuates the initiation and progression of BRCA1‐associated mammary tumors	30
Gene expression profiling improves prognostication by nomogram in patients with soft‐tissue sarcomas	29
Breaking barriers: The cGAS‐STING pathway as a novel frontier in cancer immunotherapy	29
Long‐term antibiotic use and risk of hepatocellular carcinoma later in life: a nationwide cohort study of 9.8 million participants	29
Neuroinflammation drives apathy in cancer cachexia	29
circCAPRIN1 interacts with STAT2 to promote tumor progression and lipid synthesis via upregulating ACC1 expression in colorectal cancer	29
Spatial metabolomics for evaluating response to neoadjuvant therapy in non‐small cell lung cancer patients	28
The E3 ubiquitin ligase HUWE1 acts through the N‐Myc‐DLL1‐NOTCH1 signaling axis to suppress glioblastoma progression	27
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Cover Image, Volume 44, Issue 4	27
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Sunitinib in metastatic renal cell carcinoma: clinical outcomes across risk groups in a Turkish Oncology Group Kidney Cancer Consortium	27
Single‐cell and bulk transcriptomics identifies a tumor‐specific CD36+ cancer‐associated fibroblast subpopulation in colorectal cancer	27
N‐acetyltransferase 10 promotes colon cancer progression by inhibiting ferroptosis through N4‐acetylation and stabilization of ferroptosis suppressor protein 1 (FSP1) mRNA	27
Knowing nodal Rouviére: the power of human intelligence in toxicity reduction	27
Galectin 3‐binding protein (LGALS3BP) depletion attenuates hepatic fibrosis by reducing transforming growth factor‐β1 (TGF‐β1) availability and inhibits hepatocarcinogenesis	26
Combination of photodynamic therapy and stimulator of interferon genes (STING) agonist inhibits colorectal tumor growth and recurrence	26
Breaking barriers: Smart vaccine platforms for cancer immunomodulation	26
Lipid metabolism reprograming by SREBP1‐PCSK9 targeting sensitizes pancreatic cancer to immunochemotherapy	25
Enhancement of CAR‐T cell activity against cholangiocarcinoma by simultaneous knockdown of six inhibitory membrane proteins	25
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Pancreatic cancer survival trends in the US from 2001 to 2014: a CONCORD‐3 study	25
DNA methylation signature predicts cancer response to demethylation agents from profiling diverse cancer cell lines	25
Effect of neutrophils on tumor immunity and immunotherapy resistance with underlying mechanisms	24
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Tumor microenvironment signaling and therapeutics in cancer progression	24
Cover Image, Volume 43, Issue 6	24
Ex vivo STAT3 phosphorylation in circulating immune cells: a novel biomarker for early cancer diagnosis and response to anti‐PD‐1 therapy	23
Leptin‐mediated suppression of lipoprotein lipase cleavage enhances lipid uptake and facilitates lymph node metastasis in gastric cancer	22
Beyond success: unveiling the hidden potential of radiotherapy and immunotherapy in solid tumors	22
Advanced precision modeling reveals divergent responses of hepatocellular carcinoma to combinatorial immunotherapy	21
A single measurement of fecal hemoglobin concentration outperforms polygenic risk score in colorectal cancer risk assessment	21
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Single‐cell‐eQTL mapping in circulating immune cells reveals genetic regulation of response‐associated networks in lung cancer immunotherapy	21
Targeting ferroptosis resistance resensitizes metastatic HR+HER2− breast cancer cells to palbociclib‐hormone therapy	21
The regulatory roles and clinical significance of glycolysis in tumor	20
Perivascular localized cells commit erythropoiesis in PDGF‐B‐expressing solid tumors	20
Enhancing sensitivity of triple‐negative breast cancer to DNA‐damaging therapy through chemical inhibition of the m6A methyltransferase METTL3	20
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Proteomic identification of new diagnostic biomarkers of early‐stage cutaneous mycosis fungoides	19
Infection complications in febrile chimeric antigen receptor (CAR)‐T recipients during the peri‐CAR‐T cell treatment period examined using metagenomic next‐generation sequencing (mNGS)	19
Real‐world outcomes of niraparib treatment in patients with ovarian cancer: a multicenter non‐interventional study in China	19
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Safety and immunogenicity of a third dose of mRNA‐1273 vaccine among cancer patients	19
Tumor‐derived insulin‐like growth factor‐binding protein‐1 contributes to resistance of hepatocellular carcinoma to tyrosine kinase inhibitors	18
In vivo intratumoral heterogeneity in a dish: scalable forebrain organoid models of embryonal brain tumors for high‐throughput personalized drug discovery	17
The SARS‐CoV‐2 spike protein induces lung cancer migration and invasion in a TLR2‐dependent manner	17
Targeting N4‐acetylcytidine suppresses hepatocellular carcinoma progression by repressing eEF2‐mediated HMGB2 mRNA translation	17
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HMGB3 promotes brain metastasis of lung adenocarcinoma by recruiting SSBP1 for nuclear translocation to remodel mitochondrial metabolism	17
Ferroptosis in cancer and cancer immunotherapy	17
Concurrent chemoradiotherapyof different radiation doses and different irradiation fields for locally advanced thoracic esophageal squamous cell carcinoma: A randomized, multicenter, phase III clinica	17
Evolution of tumor microenvironment in colorectal liver metastases under treatment stress	17
Lysosomal TMEM9‐LAMTOR4‐controlled mTOR signaling integrity is required for mammary tumorigenesis	17
Single‐cell atlas reveals a distinct immune profile fostered by T cell‐B cell crosstalk in triple negative breast cancer	17
Smoking, smoking cessation, and survival after cancer diagnosis in 128,423 patients across cancer types	16
Dlk1 is a novel adrenocortical stem/progenitor cell marker that predicts malignancy in adrenocortical carcinoma	16
Unraveling the routes to distant metastases in colorectal cancer: Tumor deposits and lymph node metastases as the gateway	16
NHE7 upregulation potentiates the uptake of small extracellular vesicles by enhancing maturation of macropinosomes in hepatocellular carcinoma	16
Discovery of a novel viroid‐like circular RNA in colorectal cancer	16
Transient and DNA‐free in vivo CRISPR/Cas9 genome editing for flexible modeling of endometrial carcinogenesis	15
Combination of anti‐PD‐L1 antibody with peptide MEL‐dKLA targeting M2 tumor‐associated macrophages suppresses breast cancer metastasis	15
Diagnostic value of genetic mutation analysis and mutation profiling of cell‐free DNA in intraocular fluid for vitreoretinal lymphoma	15
ABTL0812 enhances antitumor effect of paclitaxel and reverts chemoresistance in triple‐negative breast cancer models	15
Targeted STAT1 therapy for LZTR1‐driven peripheral nerve sheath tumor	15
RNA m 1 A methyltransferase TRMT61A promotes colorectal tumorigenesis by enhancing ONECUT2 mRNA stabil	15
Efficacy, safety and biomarkers of SG001 for patients with previously treated recurrent or metastatic cervical cancer: an open‐label, multicenter, phase Ib trial	15
Cover Image, Volume 43, Issue 12	14
Exciting progress in targeted therapy innovation for unresectable stage III EGFR‐mutated NSCLC: the phase III LAURA study	14
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Cancer diagnosis is one quarter lower than the expected cancer incidence in the first year of COVID‐19 pandemic in Germany: A retrospective register‐based cohort study	14
A phase II study on Mefatinib as first‐line treatment of patients with advanced non‐small‐cell lung cancer harboring uncommon EGFR mutations	14
Methionine restriction sensitizes cancer cells to immunotherapy	13
Combining methylated SEPTIN9 and RNF180 plasma markers for diagnosis and early detection of gastric cancer	13
Blockage of EGFR/AKT and mevalonate pathways synergize the antitumor effect of temozolomide by reprogramming energy metabolism in glioblastoma	13

Combating cancer immunotherapy resistance: a nano‐medicine perspective	13
Engineering heavy chain antibody‐drug conjugates against solid tumors for a one‐shot kill	13
Cellular senescence and metabolic reprogramming: Unraveling the intricate crosstalk in the immunosuppressive tumor microenvironment	13
Lung cancer risk score for ever and never smokers in China	13
Cover Image, Volume 42, Issue 6	12
Vascular smooth muscle cell plasticity in the tumor microenvironment	12
Cover Image, Volume 43, Issue 9	12
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Stereotactic body radiotherapy plus cadonilimab (PD‐1/CTLA‐4 bispecific antibody) as third‐line or beyond therapy for refractory solid tumors: A phase 1b study	11
Prediction of major adverse cardiac events is the first critical task in the management of immune checkpoint inhibitor‐associated myocarditis	11
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Plasma small‐extracellular vesicles enriched in miR‐122‐5p promote disease aggressiveness in pediatric anaplastic large‐cell lymphoma	11
Lymphatic metastasis in non‐small cell lung cancer: recent discoveries and novel therapeutic targets	11
Dynamic epi‐transcriptomic landscape mapping with disease progression in estrogen receptor‐positive breast cancer	11
CD24 is a promising immunotherapeutic target for enhancing efficacy of third‐generation EGFR‐TKIs on EGFR‐mutated lung cancer	10
Transcription factor ETV4 promotes the development of hepatocellular carcinoma by driving hepatic TNF‐α signaling	10
Novel CD123×CD33 bicistronic chimeric antigen receptor (CAR)‐T therapy has potential to reduce escape from single‐target CAR‐T with no more hematotoxicity	10
The Chinese Society of Clinical Oncology (CSCO): Clinical guidelines for the diagnosis and treatment of gastric cancer, 2023	10
Nicotinamide N‐methyltransferase negatively regulates metastasis‐promoting property of cancer‐associated fibroblasts in lung adenocarcinoma	10
MFSD2A potentiates gastric cancer response to anti‐PD‐1 immunotherapy by reprogramming the tumor microenvironment to activate T cell response	10
Glutamine metabolic microenvironment drives M2 macrophage polarization to mediate trastuzumab resistance in HER2‐positive gastric cancer	10
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Targeting MAN1B1 potently enhances bladder cancer antitumor immunity via deglycosylation of CD47	10
Training the synergy between Bacillus Calmette‐Guérin and immune checkpoint‐blocking antibodies in bladder cancer	9
KRAS‐G12D mutation drives immune suppression and the primary resistance of anti‐PD‐1/PD‐L1 immunotherapy in non‐small cell lung cancer	9
Transcriptome‐wide association analysis identified candidate susceptibility genes for nasopharyngeal carcinoma	9
Intratumoral CD103+CD8+ T cells predict response to neoadjuvant chemoimmunotherapy in advanced head and neck squamous cell carcinoma	9
Treatment intensification for metastatic prostate cancer: New treatment landscapes in androgen deprivation‐based therapy	9
Multiplexed imaging of tumor immune microenvironmental markers in locally advanced or metastatic non‐small‐cell lung cancer characterizes the features of response to PD‐1 blockade plus chemotherapy	9
Cover Image, Volume 42, Issue 8	8
NAT10 regulates tumor progression and immune microenvironment in pancreatic ductal adenocarcinoma via the N4‐acetylated LAMB3‐mediated FAK/ERK pathway	8
Dietary intake of advanced glycation endproducts (AGEs) and cancer risk across more than 20 anatomical sites: A multinational cohort study	8
Perioperative toripalimab plus neoadjuvant chemotherapy might improve outcomes in resectable esophageal cancer: an interim analysis of a phase III randomized clinical trial	8
Cover Image, Volume 43, Issue 11	8
Identification of telomere maintenance gene variations related to lung adenocarcinoma risk by genome‐wide association and whole genome sequencing analyses	8
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Low level of ARID1A contributes to adaptive immune resistance and sensitizes triple‐negative breast cancer to immune checkpoint inhibitors	8
Cover Image, Volume 42, Issue 6	8
Tumor derived cell‐free nucleic acid upregulates programmed death‐ligand 1 expression in neutrophil via intracellular Toll‐like receptor signaling	8
Converting “cold” to “hot”: epigenetics strategies to improve immune therapy effect by regulating tumor‐associated immune suppressive cells	7
Semaglutide impairs bioavailability of alectinib: a note of warning based on a cross‐over pharmacokinetic drug‐drug interaction study	7
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Parkin deficiency promotes colorectal tumorigenesis and progression through RIPK3‐dependent necroptotic inflammation	7
Vitamin D3 for reducing mortality from cancer and other outcomes before, during and beyond the COVID‐19 pandemic: A plea for harvesting low‐hanging fruit	7
Survival trends of patients with non‐metastatic gastric adenocarcinoma in the US and European countries: the impact of decreasing resection rates	7
Cancer‐associated fibroblast‐derived secreted phosphoprotein 1 contributes to resistance of hepatocellular carcinoma to sorafenib and lenvatinib	7
The interplay between natural killer cells and pancreatic stellate cells in pancreatic ductal adenocarcinoma	7
A serum exosomal microRNA‐based artificial intelligence diagnostic model for highly accurate detection of hepatocellular carcinoma	7
Increased mitochondrial fission drives the reprogramming of fatty acid metabolism in hepatocellular carcinoma cells through suppression of Sirtuin 1	7
Simvastatin overcomes the pPCK1‐pLDHA‐SPRINGlac axis‐mediated ferroptosis and chemo‐immunotherapy resistance in AKT‐hyperactivated intrahepatic cholangiocarcinoma	7
Unveiling quality of clinical trial in China: from concern to confirmation	7
Serologic status and safety of inactivated Covid‐19 vaccine for hepatocellular carcinoma patients with cirrhosis after curative liver resection	7
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Phosphatidylserine released from apoptotic cells in tumor induces M2‐like macrophage polarization through the PSR‐STAT3‐JMJD3 axis	6
Enhancing antitumor immunity through the combination of cholesterolized TLR7 agonist liposomes and radiotherapy: a role for IL‐1β and the inflammasome pathway	6
Dual inhibition of sirtuins 1 and 2: reprogramming metabolic energy dynamics in chronic myeloid leukemia as an immunogenic anticancer strategy	6
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Non‐small cell lung cancer in China	6
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Comparative risk of acute kidney injury among cancer patients treated with immune checkpoint inhibitors	6
A practical overview and statistical analysis of interval‐censored data in cancer	6
Single‐cell transcriptomic analysis uncovers intratumoral heterogeneity and drug‐tolerant persister in ALK‐rearranged lung adenocarcinoma	6
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Dysfunction of dendritic cells in tumor microenvironment and immunotherapy	6
SALIRI‐based (raltitrexed plus irinotecan) therapy as a second‐line treatment for patients with metastatic colorectal cancer (SALLY): A prospective, multicenter, non‐interventional, registry study	6
Cytosolic TGM2 promotes malignant progression in gastric cancer by suppressing the TRIM21‐mediated ubiquitination/degradation of STAT1 in a GTP binding‐dependent modality	6
Fusobacterium is toxic for head and neck squamous cell carcinoma and its presence may determine a better prognosis	6
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Neutrophils in cancer: At the crucial crossroads of anti‐tumor and pro‐tumor	6
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A non‐metabolic function of hexokinase 2 in small cell lung cancer: promotes cancer cell stemness by increasing USP11‐mediated CD133 stability	6
Advances and clinical applications of immune checkpoint inhibitors in hematological malignancies	6
ZBED2 expression enhances interferon signaling and predicts better survival of estrogen receptor‐negative breast cancer patients	6
Aberrant translation regulated by METTL1/WDR4‐mediated tRNA N7‐methylguanosine modification drives head and neck squamous cell carcinoma progression	6
miR‐99a‐5p modulates doxorubicin resistance via the COX‐2/ABCG2 axis in triple‐negative breast cancer: from the discovery to in vivo studies	6
Helicobacter pylori CagA elevates FTO to induce gastric cancer progression via a “hit‐and‐run” paradigm	6
Activation mechanisms of clinically distinct B‐Raf V600E and V600K mutants	5
Evaluation of exposure‐response‐safety relationship of model‐informed low‐dose 500 mg abiraterone acetate in prostate cancer patients	5
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Immunosuppressive JAG2+ tumor‐associated neutrophils hamper PD‐1 blockade response in ovarian cancer by mediating the differentiation of effector regulatory T cells	5
Multi‐omic study to unmask genes involved in prostate cancer development in a multi‐case family	5
NAT10‐mediated ac4C‐modified ANKZF1 promotes tumor progression and lymphangiogenesis in clear‐cell renal cell carcinoma by attenuating YWHAE‐driven cytoplasmic retention of YAP1	5
Single‐cell multi‐omics reveals tumor microenvironment factors underlying poor immunotherapy responses in ALK‐positive lung cancer	5
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Unraveling the effects of screening colonoscopy on colorectal cancer early detection and prevention: the NordICC trial revisited	5
Targeted reactivation of the novel tumor suppressor DAPK1, an upstream regulator of p53, in high‐grade serous ovarian cancer by mRNA liposomes reduces viability and enhances drug sensitivity in precli	5
Cancer‐associated fibroblasts in breast cancer: Challenges and opportunities	5
Triple combination targeting PI3K, ER, and CDK4/6 inhibits growth of ER‐positive breast cancer resistant to fulvestrant and CDK4/6 or PI3K inhibitor	5
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Weakened humoral immune responses of inactivated SARS‐CoV‐2 vaccines in patients with solid tumors	5
Older adults living with gastrointestinal cancers in 2021	5