Nature Metabolism

(The TQCC of Nature Metabolism is 57. The table below lists those papers that are above that threshold based on CrossRef citation counts. The publications cover those that have been published in the past four years, i.e., from 2019-03-01 to 2023-03-01.)
Microbial regulation of organismal energy homeostasis255
The mitophagy activator urolithin A is safe and induces a molecular signature of improved mitochondrial and cellular health in humans222
Leptin and the endocrine control of energy balance187
Single-cell analysis of human adipose tissue identifies depot- and disease-specific cell types169
A network of trans-cortical capillaries as mainstay for blood circulation in long bones168
Cardiac glycosides are broad-spectrum senolytics160
Metabolic signatures of cancer cells and stem cells151
Metabolic adaptation and maladaptation in adipose tissue150
Molecular logic of mTORC1 signalling as a metabolic rheostat148
Branched-chain amino acids impact health and lifespan indirectly via amino acid balance and appetite control147
NADPH production by the oxidative pentose-phosphate pathway supports folate metabolism142
Slc12a8 is a nicotinamide mononucleotide transporter127
Metformin-induced increases in GDF15 are important for suppressing appetite and promoting weight loss119
Endothelial TGF-β signalling drives vascular inflammation and atherosclerosis118
Characterization of hypoxia-associated molecular features to aid hypoxia-targeted therapy111
Metabolic Messengers: adiponectin107
Mitochondrial complex III is necessary for endothelial cell proliferation during angiogenesis105
Metabolic Messengers: ceramides104
m6A mRNA methylation regulates human β-cell biology in physiological states and in type 2 diabetes102
Metabolic regulation of dermal fibroblasts contributes to skin extracellular matrix homeostasis and fibrosis102
Leader β-cells coordinate Ca2+ dynamics across pancreatic islets in vivo99
Lipidomics needs more standardization97
Inter-organ cross-talk in metabolic syndrome93
TGF-β2 is an exercise-induced adipokine that regulates glucose and fatty acid metabolism92
Inosine is an alternative carbon source for CD8+-T-cell function under glucose restriction87
An upper limit on Gibbs energy dissipation governs cellular metabolism87
Astrocytic mitochondrial ROS modulate brain metabolism and mouse behaviour86
Ablation of adipocyte creatine transport impairs thermogenesis and causes diet-induced obesity85
Cellular redox state constrains serine synthesis and nucleotide production to impact cell proliferation84
Spatial sorting enables comprehensive characterization of liver zonation82
Succinate accumulation drives ischaemia-reperfusion injury during organ transplantation76
Transcriptional network analysis implicates altered hepatic immune function in NASH development and resolution73
Human brown adipose tissue is phenocopied by classical brown adipose tissue in physiologically humanized mice72
Voltage-energized calcium-sensitive ATP production by mitochondria68
Two-stage metabolic remodelling in macrophages in response to lipopolysaccharide and interferon-γ stimulation65
Nrf2 controls iron homoeostasis in haemochromatosis and thalassaemia via Bmp6 and hepcidin65
MANF regulates metabolic and immune homeostasis in ageing and protects against liver damage64
Oxygen and mammalian cell culture: are we repeating the experiment of Dr. Ox?60
Integrating the inputs that shape pancreatic islet hormone release58
Liver macrophages regulate systemic metabolism through non-inflammatory factors58
An artificial intelligence decision support system for the management of type 1 diabetes57