Nature Metabolism

Papers
(The H4-Index of Nature Metabolism is 69. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-03-01 to 2024-03-01.)
ArticleCitations
Skeletal muscle energy metabolism during exercise438
SARS-CoV-2 infects and replicates in cells of the human endocrine and exocrine pancreas362
Lactate: the ugly duckling of energy metabolism356
Guidelines for measuring reactive oxygen species and oxidative damage in cells and in vivo347
Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals304
Gut microbiome pattern reflects healthy ageing and predicts survival in humans270
Acute and long-term disruption of glycometabolic control after SARS-CoV-2 infection245
Metabolites and the tumour microenvironment: from cellular mechanisms to systemic metabolism244
A metabolic handbook for the COVID-19 pandemic213
The metabolic roots of senescence: mechanisms and opportunities for intervention205
Lipolysis: cellular mechanisms for lipid mobilization from fat stores201
Senescent cells promote tissue NAD+ decline during ageing via the activation of CD38+ macrophages196
HDL-scavenger receptor B type 1 facilitates SARS-CoV-2 entry195
Short-chain fatty acids as potential regulators of skeletal muscle metabolism and function194
Fructose stimulated de novo lipogenesis is promoted by inflammation173
Metabolic and epigenetic regulation of T-cell exhaustion163
Comparative evaluation of itaconate and its derivatives reveals divergent inflammasome and type I interferon regulation in macrophages160
Type 2 diabetes influences bacterial tissue compartmentalisation in human obesity156
CD38 ecto-enzyme in immune cells is induced during aging and regulates NAD+ and NMN levels154
Metabolic Messengers: tumour necrosis factor148
Inosine is an alternative carbon source for CD8+-T-cell function under glucose restriction148
Non-alcoholic fatty liver disease: the interplay between metabolism, microbes and immunity141
Autoantibody-negative insulin-dependent diabetes mellitus after SARS-CoV-2 infection: a case report139
Exercise hormone irisin is a critical regulator of cognitive function129
A multi-omics investigation of the composition and function of extracellular vesicles along the temporal trajectory of COVID-19129
Dihydroxyacetone phosphate signals glucose availability to mTORC1129
Resolution of NASH and hepatic fibrosis by the GLP-1R and GCGR dual-agonist cotadutide via modulating mitochondrial function and lipogenesis127
Metabolic Messengers: FGF21124
Glis1 facilitates induction of pluripotency via an epigenome–metabolome–epigenome signalling cascade110
Tumour-reprogrammed stromal BCAT1 fuels branched-chain ketoacid dependency in stromal-rich PDAC tumours104
MESH1 is a cytosolic NADPH phosphatase that regulates ferroptosis102
NRF2 activation promotes the recurrence of dormant tumour cells through regulation of redox and nucleotide metabolism101
Central and peripheral GLP-1 systems independently suppress eating101
A molecular mechanism explaining albuminuria in kidney disease99
Metabolic communication during exercise96
Exercise rejuvenates quiescent skeletal muscle stem cells in old mice through restoration of Cyclin D196
Molecular consequences of SARS-CoV-2 liver tropism96
The gut microbial metabolite formate exacerbates colorectal cancer progression95
Selenium detoxification is required for cancer-cell survival95
The flavonoid procyanidin C1 has senotherapeutic activity and increases lifespan in mice94
Childhood obesity and the associated rise in cardiometabolic complications90
An artificial intelligence decision support system for the management of type 1 diabetes88
Can COVID-19 cause diabetes?86
Interleukin 6 as an energy allocator in muscle tissue86
Altered proximal tubular cell glucose metabolism during acute kidney injury is associated with mortality85
Mitochondrial pyruvate carriers are required for myocardial stress adaptation85
Meteorin-like facilitates skeletal muscle repair through a Stat3/IGF-1 mechanism85
Multiple cell types contribute to the atherosclerotic lesion fibrous cap by PDGFRβ and bioenergetic mechanisms85
Identifying strategies to target the metabolic flexibility of tumours84
GTTs and ITTs in mice: simple tests, complex answers84
The ins and outs of serine and glycine metabolism in cancer83
Space-time logic of liver gene expression at sub-lobular scale83
UCP1 governs liver extracellular succinate and inflammatory pathogenesis80
The small intestine shields the liver from fructose-induced steatosis80
Metabolic conditioning of CD8+ effector T cells for adoptive cell therapy79
POMC neuronal heterogeneity in energy balance and beyond: an integrated view79
Fasting drives the metabolic, molecular and geroprotective effects of a calorie-restricted diet in mice77
The hexosamine biosynthesis pathway is a targetable liability in KRAS/LKB1 mutant lung cancer76
Multi-omics profiling of living human pancreatic islet donors reveals heterogeneous beta cell trajectories towards type 2 diabetes75
Long-chain fatty acyl-CoA esters regulate metabolism via allosteric control of AMPK β1 isoforms75
Multifaceted mitochondria: moving mitochondrial science beyond function and dysfunction74
Nutritional modulation of heart failure in mitochondrial pyruvate carrier–deficient mice74
Pharmacological inhibition of fatty acid synthesis blocks SARS-CoV-2 replication74
Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma73
The cross-talk of energy sensing and mitochondrial anchoring sustains synaptic efficacy by maintaining presynaptic metabolism72
Safety and pharmacodynamics of an engineered E. coli Nissle for the treatment of phenylketonuria: a first-in-human phase 1/2a study70
Metabolic Messengers: glucagon-like peptide 170
Mitochondrial long non-coding RNA GAS5 tunes TCA metabolism in response to nutrient stress70
Peroxisomal β-oxidation acts as a sensor for intracellular fatty acids and regulates lipolysis70
Genome-wide discovery of genetic loci that uncouple excess adiposity from its comorbidities69
Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism69
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