OOIR: Observatory of International Research

Papers

(The median citation count of Geroscience is 14. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
Delayed effects of radiation in adipose tissue reflect progenitor damage and not cellular senescence	155
Age-dependent association of clonal hematopoiesis with COVID-19 mortality in patients over 60 years	144
Cognition and brain health among older adults in Iceland: the AGES-Reykjavik study	68
High polygenic risk score for exceptional longevity is associated with a healthy metabolic profile	64
Fast and slow skeletal myosin binding protein-C and aging	58
High-throughput sequencing analysis of nuclear-encoded mitochondrial genes reveals a genetic signature of human longevity	54
Morusin and mulberrin extend the lifespans of yeast and C. elegans via suppressing nutrient-sensing pathways	42
Aging compromises oligodendrocyte precursor cell maturation and efficient remyelination in the monkey brain	42
Is “cellular senescence” a misnomer?	42
Age-associated changes in circulatory fatty acids: new insights on adults and long-lived individuals	41
Understanding heterogeneity of responses to, and optimizing clinical efficacy of, exercise training in older adults: NIH NIA Workshop summary	39
Network analyses unveil ageing-associated pathways evolutionarily conserved from fungi to animals	38
Cathepsin F is a potential marker for senescent human skin fibroblasts and keratinocytes associated with skin aging	37
Rapid emergence of transcriptional heterogeneity upon molecular stress predisposes cells to two distinct states of senescence	37
Frailty and functional brain connectivity (FBC) in older adults with mild cognitive impairment (MCI): baseline results from the SYNERGIC Trial	36
The efficacy and safety of β-nicotinamide mononucleotide (NMN) supplementation in healthy middle-aged adults: a randomized, multicenter, double-blind, placebo-controlled, parallel-group, dose-dependen	35
Longitudinal association of executive function and structural network controllability in the aging brain	34
Bioenergetic and vascular predictors of potential super-ager and cognitive decline trajectories—a UK Biobank Random Forest classification study	32
Aging results in DNA damage and telomere dysfunction that is greater in endothelial versus vascular smooth muscle cells and is exacerbated in atheroprone regions	31
Episodic memory dysfunction and hypersynchrony in brain functional networks in cognitively intact subjects and MCI: a study of 379 individuals	31
Rapamycin not dietary restriction improves resilience against pathogens: a meta-analysis	30
Replenishment of myeloid-derived suppressor cells (MDSCs) overrides CR-mediated protection against tumor growth in a murine model of triple-negative breast cancer	28
A metabolomic signature of the APOE2 allele	28
Data-driven health deficit assessment improves a frailty index’s prediction of current cognitive status and future conversion to dementia: results from ADNI	27
Age- and time-dependent mitochondrial genotoxic and myopathic effects of beta-guanidinopropionic acid, a creatine analog, on rodent skeletal muscles	26

Lipidomics profiling of biological aging in American Indians: the Strong Heart Family Study	25
Handgrip strength is associated with learning and verbal fluency in older men without dementia: insights from the NHANES	25
Carotid disease, cognition, and aging: time to redefine asymptomatic disease?	24
Poliomyelitis is a current challenge: long-term sequelae and circulating vaccine-derived poliovirus	23
Decreased lifespan in female “Munchkin” actors from the cast of the 1939 film version of The Wizard of Oz does not support the hypothesis linking hypopituitary dwarfism to longevity	22
Liver alterations and detection of SARS-CoV-2 RNA and proteins in COVID-19 autopsies	22
Differential plasma protein expression after ingestion of essential amino acid-based dietary supplement verses whey protein in low physical functioning older adults	22
A comprehensive analysis of the mutational landscape of the newly emerging Omicron (B.1.1.529) variant and comparison of mutations with VOCs and VOIs	22
Potassium-chelating drug sodium polystyrene sulfonate enhances lysosomal function and suppresses proteotoxicity	21
Remember NIBS? tACS improves memory performance in elders with subjective memory complaints	21
Microbiota mitochondria disorders as hubs for early age-related macular degeneration	20
How size and genetic diversity shape lifespan across breeds of purebred dogs	19
Causal influences of salience/cerebellar networks on dorsal attention network subserved age-related cognitive slowing	19
Multiple myeloma, a quintessential malignant disease of aging: a geroscience perspective on pathogenesis and treatment	18
Metabolic and molecular responses of human patellar tendon to concentric- and eccentric-type exercise in youth and older age	18
Neither myonuclear accretion nor a myonuclear domain size ceiling is a feature of the attenuated hypertrophic potential of aged human skeletal muscle	17
White matter hyperintensity load varies depending on subjective cognitive decline criteria	17
Is an MRI-derived anatomical measure of dementia risk also a measure of brain aging?	17
Associations between biomarkers of cellular senescence and physical function in humans: observations from the lifestyle interventions for elders (LIFE) study	16
A long-term obesogenic high-fat diet in mice partially dampens the anti-frailty benefits of late-life intermittent fasting	14