OOIR: Observatory of International Research

Papers

(The H4-Index of Geroscience is 35. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)

Article	Citations
Delayed effects of radiation in adipose tissue reflect progenitor damage and not cellular senescence	111
Epigenetic clock and methylation studies in marsupials: opossums, Tasmanian devils, kangaroos, and wallabies	108
CYB5R3 overexpression preserves skeletal muscle mitochondria and autophagic signaling in aged transgenic mice	83
Cognition and brain health among older adults in Iceland: the AGES-Reykjavik study	80
Age-dependent association of clonal hematopoiesis with COVID-19 mortality in patients over 60 years	72
Unbiased proteomic analysis of extracellular vesicles secreted by senescent human vascular smooth muscle cells reveals their ability to modulate immune cell functions	59
Perceived social isolation is correlated with brain structure and cognitive trajectory in Alzheimer’s disease	59
Evaluation of a blood-based geroscience biomarker index in a randomized trial of caloric restriction and exercise in older adults with heart failure with preserved ejection fraction	58
Elevated α-synuclein and NfL levels in tear fluids and decreased retinal microvascular densities in patients with Parkinson’s disease	56
Cannabidiol induces autophagy and improves neuronal health associated with SIRT1 mediated longevity	56
Vitamin D supplementation is associated with slower epigenetic aging	54
Investigating the combination of plasma amyloid-beta and geroscience biomarkers on the incidence of clinically meaningful cognitive decline in older adults	53
High polygenic risk score for exceptional longevity is associated with a healthy metabolic profile	53
Senolytic treatment rescues blunted muscle hypertrophy in old mice	53
Impact of medium-chain triglycerides on gait performance and brain metabolic network in healthy older adults: a double-blind, randomized controlled study	50
Fast and slow skeletal myosin binding protein-C and aging	50
Evidence for preserved insulin responsiveness in the aging rat brain	50
Lipidomic signatures from physically frail and robust older adults at hospital admission	50
Age-dependent frequency of unconventional T cells in a healthy adult Caucasian population: a combinational study of invariant natural killer T cells, γδ T cells, and mucosa-associated invariant T cell	47
Aging alters antiviral signaling pathways resulting in functional impairment in innate immunity in response to pattern recognition receptor agonists	46
Prediction of disability-free survival in healthy older people	45
Clonal hematopoiesis is not prevalent in Hutchinson-Gilford progeria syndrome	45
Effect of simultaneous exercise and cognitive training on executive functions, baroreflex sensitivity, and pre-frontal cortex oxygenation in healthy older adults: a pilot study	43
Single-cell transcriptomics identifies premature aging features of TERC-deficient mouse brain and bone marrow	42
Stringent public health measures during COVID-19 across ischemic stroke care systems: the potential impact of patient perceptions on health care-seeking behaviors	42

Correction to: Early dysfunction of functional connectivity in healthy elderly with subjective memory complaints	42
Aging compromises oligodendrocyte precursor cell maturation and efficient remyelination in the monkey brain	40
Is “cellular senescence” a misnomer?	39
Brain age estimation reveals older adults’ accelerated senescence after traumatic brain injury	39
High-throughput sequencing analysis of nuclear-encoded mitochondrial genes reveals a genetic signature of human longevity	39
Associations between sociodemographic factors, health spending, disease burden, and life expectancy of older adults (70 + years old) in 22 countries in the Western Pacific Region, 1995–2019: estimates	39
Circulating interleukin-37 declines with aging in healthy humans: relations to healthspan indicators and IL37 gene SNPs	39
Understanding heterogeneity of responses to, and optimizing clinical efficacy of, exercise training in older adults: NIH NIA Workshop summary	38
Continent-wide evolutionary trends of emerging SARS-CoV-2 variants: dynamic profiles from Alpha to Omicron	38
Subclinical cognitive deficits are associated with reduced cerebrovascular response to visual stimulation in mid-sixties men	36
Age-associated changes in circulatory fatty acids: new insights on adults and long-lived individuals	35
Morusin and mulberrin extend the lifespans of yeast and C. elegans via suppressing nutrient-sensing pathways	35
SGLT2 inhibition attenuates arterial dysfunction and decreases vascular F-actin content and expression of proteins associated with oxidative stress in aged mice	35