OOIR: Observatory of International Research

Papers

(The H4-Index of Geroscience is 33. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
A toolkit for quantification of biological age from blood chemistry and organ function test data: BioAge	99
Monkeypox: considerations for the understanding and containment of the current outbreak in non-endemic countries	72
Intermittent fasting: from calories to time restriction	63
Comparison of antibody and T cell responses elicited by BBIBP-CorV (Sinopharm) and BNT162b2 (Pfizer-BioNTech) vaccines against SARS-CoV-2 in healthy adult humans	63
Omicron variant of the SARS-CoV-2: a quest to define the consequences of its high mutational load	53
The efficacy and safety of β-nicotinamide mononucleotide (NMN) supplementation in healthy middle-aged adults: a randomized, multicenter, double-blind, placebo-controlled, parallel-group, dose-dependen	51
Treatment with the BCL-2/BCL-xL inhibitor senolytic drug ABT263/Navitoclax improves functional hyperemia in aged mice	50
Role of inflammatory markers in the diagnosis of vascular contributions to cognitive impairment and dementia: a systematic review and meta-analysis	48
Regulation of TDP-43 phosphorylation in aging and disease	48
Plasma dilution improves cognition and attenuates neuroinflammation in old mice	46
Oral frailty indicators to target major adverse health-related outcomes in older age: a systematic review	46
Targeting mitochondrial dysfunction with small molecules in intervertebral disc aging and degeneration	41
Endothelial deficiency of insulin-like growth factor-1 receptor (IGF1R) impairs neurovascular coupling responses in mice, mimicking aspects of the brain aging phenotype	41
IGF1R signaling regulates astrocyte-mediated neurovascular coupling in mice: implications for brain aging	41
Grip strength performance from 9431 participants of the GenoFit study: normative data and associated factors	40
Mesenchymal stromal cell-derived small extracellular vesicles promote neurological recovery and brain remodeling after distal middle cerebral artery occlusion in aged rats	38
Muscle and tendon adaptations to moderate load eccentric vs. concentric resistance exercise in young and older males	37
Senescent macrophages in the human adipose tissue as a source of inflammaging	36
Omicron variant (B.1.1.529) of SARS-CoV-2: understanding mutations in the genome, S-glycoprotein, and antibody-binding regions	36
A robust machine learning framework to identify signatures for frailty: a nested case-control study in four aging European cohorts	36
Long-term exercise pre-training attenuates Alzheimer’s disease–related pathology in a transgenic rat model of Alzheimer’s disease	36
Analysis of complexity in the EEG activity of Parkinson’s disease patients by means of approximate entropy	36
Necroptosis increases with age in the brain and contributes to age-related neuroinflammation	35
Diabetes mellitus correlates with increased biological age as indicated by clinical biomarkers	35
Age-related decline in circulating IGF-1 associates with impaired neurovascular coupling responses in older adults	35

Quest for a summary measure of biological age: the health and retirement study	35
Profiling age-related muscle weakness and wasting: neuromuscular junction transmission as a driver of age-related physical decline	35
Obesity as a premature aging phenotype — implications for sarcopenic obesity	34
Targeting senescent retinal pigment epithelial cells facilitates retinal regeneration in mouse models of age-related macular degeneration	34
Blood–brain barrier leakage at baseline and cognitive decline in cerebral small vessel disease: a 2-year follow-up study	34
An energetics perspective on geroscience: mitochondrial protonmotive force and aging	33
Systemic inflammatory markers in relation to cognitive function and measures of brain atrophy: a Mendelian randomization study	33
Spatial transcriptomic analysis reveals inflammatory foci defined by senescent cells in the white matter, hippocampi and cortical grey matter in the aged mouse brain	33
Senolytic treatment rescues blunted muscle hypertrophy in old mice	33