OOIR: Observatory of International Research

Papers

(The TQCC of APL Bioengineering is 9. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)

Article	Citations
Thermosensitive hydrogel carrying extracellular vesicles from adipose-derived stem cells promotes peripheral nerve regeneration after microsurgical repair	78
Synergy between photonics and biological approaches—A review of combination therapies for cancer theranostics	75
Scheduled dosage regimen by irreversible electroporation of loaded erythrocytes for cancer treatment	71
Design and implementation of a microfluidic device capable of temporal growth factor delivery reveal filtering capabilities of the EGFR/ERK pathway	65
The yellow brick road to nuclear membrane mechanotransduction	43
Adenine base editing rescues pathogenic phenotypes in tissue engineered vascular model of Hutchinson-Gilford progeria syndrome	39
Substrate stiffness modulates collective colony expansion of the social bacterium Myxococcus xanthus	37
Aqueous electrolyte-gated solution-processed metal oxide transistors for direct cellular interfaces	35
Engineering CAR T cells for enhanced efficacy and safety	31
A low-profile electromechanical packaging system for soft-to-flexible bioelectronic interfaces	31
Proteomics of human platelet lysates and insight from animal studies on platelet protein diffusion to hippocampus upon intranasal administration	31
Black phosphorus-enhanced injectable hydrogel for infected soft tissue healing	30
Electrophysiological features of cortical 3D networks are deeply modulated by scaffold properties	27
Evaluation of chromatin mesoscale organization	26
Geometrically engineered organoid units and their assembly for pre-construction of organ structures	25
3D bioprinted human iPSC-derived neural progenitor cells as a novel platform for studying neurogenic niche	25
Exploring the translational impact of type 1 diabetes on cerebral neurovascular function through ECoG-LSCI	24
Computational modeling of the physical features that influence breast cancer invasion into adipose tissue	23
Unpleasant odors compared to pleasant ones cause higher cortical activations detectable by fNIRS and observable mostly in females	23
GelMA micropattern enhances cardiomyocyte organization, maturation, and contraction via contact guidance	22
The mechanobiology of nuclear phase separation	22
Machine learning-informed predictions of nanoparticle mobility and fate in the mucus barrier	21
A fully automated deep learning approach for coronary artery segmentation and comprehensive characterization	21
A novel portable in situ printer for hydrogel multi-structure molding and cell printing	20
Model discovery approach enables noninvasive measurement of intra-tumoral fluid transport in dynamic MRI	20

Fibroblast senescence-associated extracellular matrix promotes heterogeneous lung niche	20
Learning discrete structures for cancer radiomics	19
Current state of the art and future directions for implantable sensors in medical technology: Clinical needs and engineering challenges	19
Non-contact radiofrequency stimulation to the olfactory nerve of human subjects	18
A comprehensive review of graphene-based biosensors: Fabrication, applications, characterization and future perspectives—A review	18
Degradation-aware neural imputation: Advancing decoding stability in brain machine interfaces	18
The role of biomechanical factors in models of intervertebral disc degeneration across multiple length scales	18
Immunogenic cell death-related cancer-associated fibroblast clusters and prognostic risk model in cervical cancer	17
Advancements in textile techniques for cardiovascular tissue replacement and repair	17
Orthopedic meta-implants	17
Mechanism study on the influences of buffer osmotic pressure on microfluidic chip-based cell electrofusion	17
M/EEG source localization for both subcortical and cortical sources using a convolutional neural network with a realistic head conductivity model	17
Model of collective detachment in high-grade serous ovarian cancer demonstrates that tumor spheroids produce ECM to support metastatic processes	17
Fluorescence spectroscopy as a novel tool in hematological diagnostics	16
A review: Blood pressure monitoring based on PPG and circadian rhythm	15
TTLL4 mediates the PI3K/AKT/MDM2 pathway to promote hepatocellular carcinoma progression and predict patient prognosis	15
Differential effects of vascular endothelial growth factor on glycocalyx of endothelial and tumor cells and potential targets for tumor metastasis	15
Terahertz in vivo imaging of human skin: Toward detection of abnormal skin pathologies	15
Advanced biomaterial strategies for overcoming age-associated wound healing impairments	15
Injectable photosensitive bone cement enhancing angiogenesis and osteogenic differentiation for the treatment of bone nonunion	14
Hyaluronic acid turnover controls the severity of cerebral cavernous malformations in bioengineered human micro-vessels	14
Regulation of airway remodeling in asthma: The synergistic effects of nanotechnology and Hippo pathway activation	14
CAR T cell infiltration and cytotoxic killing within the core of 3D breast cancer spheroids under the control of antigen sensing in microwell arrays	14
Long-term effect of sodium selenite on the integrity and permeability of on-chip microvasculature	13
In vivo label-free tissue histology through a microstructured imaging window	13
Mechanical cues orchestrate monocyte behavior in immune regulation and disease	13
Altered blood flow due to larger aortic diameters in patients with transcatheter heart valve thrombosis	13
Single-cell RNA and bulk sequencing analysis reveals that formononetin inhibits GTSF1 to exert anti-osteosarcoma effects	13
Publisher's Note: “Contrast-enhanced ultrasound tracking of helical propellers with acoustic phase analysis and comparison with color Doppler” [APL Bioeng. 6, 036102 (2022)]	12
Fluid flow to mimic organ function in 3D in vitro models	12
Bioengineering of the liver	12
Quercetin targets the Ccl4–Ccr5 axis to relieve neuropathic pain after spinal cord injury	12
Improvement of clinical wound microcirculation diagnosis using an object tracking-based laser speckle contrast imaging system	12
The effects of strain history on aortic valve interstitial cell activation in a 3D hydrogel environment	12
Investigations on artificially extending the spectral range of natural vision	12
A patient-specific echogenic soft robotic left ventricle embedded into a closed-loop cardiovascular simulator for advanced device testing	11
Biosensors integrated within wearable devices for monitoring chronic wound status	11
FRESH™ 3D bioprinted cardiac tissue, a bioengineered platform for in vitro pharmacology	11
Collagen density regulates tip–stalk cell rearrangement during angiogenesis via cellular bioenergetics	11
Single-pericyte nanomechanics measured by contraction cytometry	11
Mechanobiology of the cell nucleus	11
High-throughput quantitation of human neutrophil recruitment and functional responses in an air-blood barrier array	10
Magnetic self-assembly of 3D multicellular microscaffolds: A biomimetic brain tumor-on-a-chip for drug delivery and selectivity testing	10
Photoplethysmography-based HRV analysis and machine learning for real-time stress quantification in mental health applications	10
Interacting with tumor cells weakens the intrinsic clockwise chirality of endothelial cells	10
Modeling nitric oxide diffusion and plasticity modulation in cerebellar learning	10
Mechanosensitive miR-99b mediates the regulatory effect of matrix stiffness on bone marrow mesenchymal stem cell fate both in vitro and in vivo	10
Hemodynamics of thrombus formation in intracranial aneurysms: An in silico observational study	10
Nuclear mechanoprotection: From tissue atlases as blueprints to distinctive regulation of nuclear lamins	10
A high throughput cell stretch device for investigating mechanobiology in vitro	10

Nondestructive, quantitative viability analysis of 3D tissue cultures using machine learning image segmentation	9
Publisher's Note: “Magneto-responsive hyaluronan hydrogel for hyperthermia and bioprinting: Magnetic, rheological properties and biocompatibility” [APL Bioeng. 7, 036113 (2023)]	9
Burst sine wave electroporation (B-SWE) for expansive blood–brain barrier disruption and controlled non-thermal tissue ablation for neurological disease	9
Imaging of the vascular distribution of the outer ear using optical coherence tomography angiography for highly accurate positioning of a hearable sensor	9
PEDOT:PSS-coated platinum electrodes for neural stimulation	9
Engineering approaches for understanding mechanical memory in cancer metastasis	9
Epigenetic regulation and mechanobiological adaptation in tenocytes during maturation	9
Surface electromyography using dry polymeric electrodes	9
Rapid flowing cells localization enabled by spatiotemporal manipulation of their holographic patterns	9
Engineered matrix microenvironments reveal the heterogeneity of liver sinusoidal endothelial cell phenotypic responses	9
Cerebellar contribution to multisensory integration: A computational modeling exploration	9
Stem cell mechanoadaptation. II. Microtubule stabilization and substrate compliance effects on cytoskeletal remodeling	9