OOIR: Observatory of International Research

Papers

(The TQCC of APL Bioengineering is 8. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)

Article	Citations
Adenine base editing rescues pathogenic phenotypes in tissue engineered vascular model of Hutchinson-Gilford progeria syndrome	75
A low-profile electromechanical packaging system for soft-to-flexible bioelectronic interfaces	63
Black phosphorus-enhanced injectable hydrogel for infected soft tissue healing	59
Thermosensitive hydrogel carrying extracellular vesicles from adipose-derived stem cells promotes peripheral nerve regeneration after microsurgical repair	55
Design and implementation of a microfluidic device capable of temporal growth factor delivery reveal filtering capabilities of the EGFR/ERK pathway	42
The yellow brick road to nuclear membrane mechanotransduction	35
Engineering CAR T cells for enhanced efficacy and safety	34
Scheduled dosage regimen by irreversible electroporation of loaded erythrocytes for cancer treatment	30
Aqueous electrolyte-gated solution-processed metal oxide transistors for direct cellular interfaces	30
Proteomics of human platelet lysates and insight from animal studies on platelet protein diffusion to hippocampus upon intranasal administration	30
Substrate stiffness modulates collective colony expansion of the social bacterium Myxococcus xanthus	29
GelMA micropattern enhances cardiomyocyte organization, maturation, and contraction via contact guidance	28
The mechanobiology of nuclear phase separation	28
Computational modeling of the physical features that influence breast cancer invasion into adipose tissue	24
Exploring the translational impact of type 1 diabetes on cerebral neurovascular function through ECoG-LSCI	24
A fully automated deep learning approach for coronary artery segmentation and comprehensive characterization	23
Fibroblast senescence-associated extracellular matrix promotes heterogeneous lung niche	22
Unpleasant odors compared to pleasant ones cause higher cortical activations detectable by fNIRS and observable mostly in females	21
Evaluation of chromatin mesoscale organization	21
Geometrically engineered organoid units and their assembly for pre-construction of organ structures	21
Erratum: “New contrast agents for photoacoustic imaging and theranostics: Recent 5-year overview on phthalocyanine/naphthalocyanine-based nanoparticles” [APL Bioeng. 5, 031510 (2021)]	21
A novel portable in situ printer for hydrogel multi-structure molding and cell printing	20
Machine learning-informed predictions of nanoparticle mobility and fate in the mucus barrier	20
Electrophysiological features of cortical 3D networks are deeply modulated by scaffold properties	19
Model discovery approach enables noninvasive measurement of intra-tumoral fluid transport in dynamic MRI	18

Mechanism study on the influences of buffer osmotic pressure on microfluidic chip-based cell electrofusion	18
Learning discrete structures for cancer radiomics	18
Orthopedic meta-implants	17
The role of biomechanical factors in models of intervertebral disc degeneration across multiple length scales	17
Degradation-aware neural imputation: Advancing decoding stability in brain machine interfaces	17
Non-contact radiofrequency stimulation to the olfactory nerve of human subjects	17
Fluorescence spectroscopy as a novel tool in hematological diagnostics	16
Advancements in textile techniques for cardiovascular tissue replacement and repair	16
Current state of the art and future directions for implantable sensors in medical technology: Clinical needs and engineering challenges	16
Immunogenic cell death-related cancer-associated fibroblast clusters and prognostic risk model in cervical cancer	16
Model of collective detachment in high-grade serous ovarian cancer demonstrates that tumor spheroids produce ECM to support metastatic processes	15
Terahertz in vivo imaging of human skin: Toward detection of abnormal skin pathologies	15
In vivo label-free tissue histology through a microstructured imaging window	15
M/EEG source localization for both subcortical and cortical sources using a convolutional neural network with a realistic head conductivity model	15
Differential effects of vascular endothelial growth factor on glycocalyx of endothelial and tumor cells and potential targets for tumor metastasis	14
Injectable photosensitive bone cement enhancing angiogenesis and osteogenic differentiation for the treatment of bone nonunion	14
Altered blood flow due to larger aortic diameters in patients with transcatheter heart valve thrombosis	14
Hyaluronic acid turnover controls the severity of cerebral cavernous malformations in bioengineered human micro-vessels	14
Advanced biomaterial strategies for overcoming age-associated wound healing impairments	14
TTLL4 mediates the PI3K/AKT/MDM2 pathway to promote hepatocellular carcinoma progression and predict patient prognosis	14
Publisher's Note: “Contrast-enhanced ultrasound tracking of helical propellers with acoustic phase analysis and comparison with color Doppler” [APL Bioeng. 6, 036102 (2022)]	13
Regulation of airway remodeling in asthma: The synergistic effects of nanotechnology and Hippo pathway activation	13
Quercetin targets the Ccl4–Ccr5 axis to relieve neuropathic pain after spinal cord injury	13
A review: Blood pressure monitoring based on PPG and circadian rhythm	13
The effects of strain history on aortic valve interstitial cell activation in a 3D hydrogel environment	13
CAR T cell infiltration and cytotoxic killing within the core of 3D breast cancer spheroids under the control of antigen sensing in microwell arrays	13
Long-term effect of sodium selenite on the integrity and permeability of on-chip microvasculature	12
Fluid flow to mimic organ function in 3D in vitro models	12
Bioengineering of the liver	12
Improvement of clinical wound microcirculation diagnosis using an object tracking-based laser speckle contrast imaging system	12
Mechanical cues orchestrate monocyte behavior in immune regulation and disease	12
Investigations on artificially extending the spectral range of natural vision	12
Single-cell RNA and bulk sequencing analysis reveals that formononetin inhibits GTSF1 to exert anti-osteosarcoma effects	12
Collagen density regulates tip–stalk cell rearrangement during angiogenesis via cellular bioenergetics	11
Mechanobiology of the cell nucleus	11
Single-pericyte nanomechanics measured by contraction cytometry	11
Interacting with tumor cells weakens the intrinsic clockwise chirality of endothelial cells	10
Mechanosensitive miR-99b mediates the regulatory effect of matrix stiffness on bone marrow mesenchymal stem cell fate both in vitro and in vivo	10
Biosensors integrated within wearable devices for monitoring chronic wound status	10
A patient-specific echogenic soft robotic left ventricle embedded into a closed-loop cardiovascular simulator for advanced device testing	10
FRESH™ 3D bioprinted cardiac tissue, a bioengineered platform for in vitro pharmacology	10
Hemodynamics of thrombus formation in intracranial aneurysms: An in silico observational study	10
Photoplethysmography-based HRV analysis and machine learning for real-time stress quantification in mental health applications	9
High-throughput quantitation of human neutrophil recruitment and functional responses in an air-blood barrier array	9
Engineered matrix microenvironments reveal the heterogeneity of liver sinusoidal endothelial cell phenotypic responses	9
Nuclear mechanoprotection: From tissue atlases as blueprints to distinctive regulation of nuclear lamins	9
A high throughput cell stretch device for investigating mechanobiology in vitro	9
PEDOT:PSS-coated platinum electrodes for neural stimulation	9
Rapid flowing cells localization enabled by spatiotemporal manipulation of their holographic patterns	9
Publisher's Note: “Skin-on-a-chip models: General overview and future perspectives” [APL Bioengineering 5, 030901 (2021)]	9

Modeling nitric oxide diffusion and plasticity modulation in cerebellar learning	9
Magnetic self-assembly of 3D multicellular microscaffolds: A biomimetic brain tumor-on-a-chip for drug delivery and selectivity testing	9
Cerebellar contribution to multisensory integration: A computational modeling exploration	9
Surface electromyography using dry polymeric electrodes	8
Nondestructive, quantitative viability analysis of 3D tissue cultures using machine learning image segmentation	8
Hepatocyte cultures: From collagen gel sandwiches to microfluidic devices with integrated biosensors	8
Engineering approaches for understanding mechanical memory in cancer metastasis	8
Epigenetic regulation and mechanobiological adaptation in tenocytes during maturation	8
Publisher's Note: “Magneto-responsive hyaluronan hydrogel for hyperthermia and bioprinting: Magnetic, rheological properties and biocompatibility” [APL Bioeng. 7, 036113 (2023)]	8
Low-intensity pulsed ultrasound irradiation ameliorates gut inflammation and neuroinflammation in mice with DSS-induced colitis	8
Burst sine wave electroporation (B-SWE) for expansive blood–brain barrier disruption and controlled non-thermal tissue ablation for neurological disease	8
Survivin as a mediator of stiffness-induced cell cycle progression and proliferation of vascular smooth muscle cells	8
Stem cell mechanoadaptation. II. Microtubule stabilization and substrate compliance effects on cytoskeletal remodeling	8