OOIR: Observatory of International Research

Papers

(The TQCC of APL Bioengineering is 8. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-02-01 to 2025-02-01.)

Article	Citations
Machine learning based approach to pH imaging and classification of single cancer cells	165
In vivo laser speckle contrast imaging of 4-aminopyridine- or pentylenetetrazole-induced seizures	135
The yellow brick road to nuclear membrane mechanotransduction	98
Computational pulmonary edema: A microvascular model of alveolar capillary and interstitial flow	80
On the nuclear pore complex and its emerging role in cellular mechanotransduction	60
A low-profile electromechanical packaging system for soft-to-flexible bioelectronic interfaces	54
Mechanobiology of the cell nucleus	52
Studying the roles of salt ions in the pore initiation and closure stages in the biomembrane electroporation	52
Insights into the mechanobiology of cancer metastasis via microfluidic technologies	46
Biophysical perspectives to understanding cancer-associated fibroblasts	46
Electrodynamic interaction between tumor treating fields and microtubule electrophysiological activities	40
FRESH™ 3D bioprinted cardiac tissue, a bioengineered platform for in vitro pharmacology	37
Collagen density regulates tip–stalk cell rearrangement during angiogenesis via cellular bioenergetics	36
Memory in repetitive protein–protein interaction series	35
Engineered tissue geometry and Plakophilin-2 regulate electrophysiology of human iPSC-derived cardiomyocytes	31
Targeting the ADPKD methylome using nanoparticle-mediated combination therapy	31
Fibroblast clearance of damaged tissue following laser ablation in engineered microtissues	28
Long-term day-by-day tracking of microvascular networks sprouting in fibrin gels: From detailed morphological analyses to general growth rules	27
Synergistic prevention and reparative effects of sesquiterpene farnesol in a rabbit model of surgical resection-induced osteoarthritis	27
Neovascularization of engineered tissues for clinical translation: Where we are, where we should be?	26
A tissue-engineered model of the atherosclerotic plaque cap: Toward understanding the role of microcalcifications in plaque rupture	24
Multimodal mechano-microscopy reveals mechanical phenotypes of breast cancer spheroids in three dimensions	24
Design and implementation of a microfluidic device capable of temporal growth factor delivery reveal filtering capabilities of the EGFR/ERK pathway	24
Direct differentiation of human pluripotent stem cells into vascular network along with supporting mural cells	23
A patient-specific echogenic soft robotic left ventricle embedded into a closed-loop cardiovascular simulator for advanced device testing	23

Scheduled dosage regimen by irreversible electroporation of loaded erythrocytes for cancer treatment	22
Single-pericyte nanomechanics measured by contraction cytometry	22
Decoding bladder state from pudendal intraneural signals in pigs	22
Liver–Heart on chip models for drug safety	22
Revisiting tissue tensegrity: Biomaterial-based approaches to measure forces across length scales	21
Organs-on-chips: Advanced engineered living systems	20
Surface engineering at the nanoscale: A way forward to improve coronary stent efficacy	20
IgG and IgM differentiation in a particle-based agglutination assay by control over antigen surface density	19
Aqueous electrolyte-gated solution-processed metal oxide transistors for direct cellular interfaces	19
The role of mechanobiology in bone and cartilage model systems in characterizing initiation and progression of osteoarthritis	18
Functional biomaterials	18
Toward improved models of human cancer: Two perspectives	17
Mechanoimmunology: Are inflammatory epigenetic states of macrophages tuned by biophysical factors?	17
Microtechnology-based in vitro models: Mimicking liver function and pathophysiology	17
Biofabrication of tissue engineering vascular systems	17
Proteomics of human platelet lysates and insight from animal studies on platelet protein diffusion to hippocampus upon intranasal administration	16
Black phosphorus-enhanced injectable hydrogel for infected soft tissue healing	16
Thermosensitive hydrogel carrying extracellular vesicles from adipose-derived stem cells promotes peripheral nerve regeneration after microsurgical repair	15
Revolutionizing biomedical research: The imperative need for heart–kidney-connected organoids	15
New insights into the biomimetic design and biomedical applications of bioengineered bone microenvironments	15
The effects of surface topography modification on hydrogel properties	15
Remodeling of an in vitro microvessel exposed to cyclic mechanical stretch	15
Stem cell mechanoadaptation. I. Effect of microtubule stabilization and volume changing stresses on cytoskeletal remodeling	15
Stacking model framework reveals clinical biochemical data and dietary behavior features associated with type 2 diabetes: A retrospective cohort study	13
Multifunctional scaffolds for biomedical applications: Crafting versatile solutions with polycaprolactone enriched by graphene oxide	13
Modeling the tumor immune microenvironment for drug discovery using 3D culture	13
Microfluidic techniques for isolation, formation, and characterization of circulating tumor cells and clusters	13
Engineering CAR T cells for enhanced efficacy and safety	13
Nuclear lamins: Structure and function in mechanobiology	13
Injectable, macroporous scaffolds for delivery of therapeutic genes to the injured spinal cord	13
Finite element analysis of electric field distribution during direct current stimulation of the spinal cord: Implications for device design	12
Substrate stiffness modulates collective colony expansion of the social bacterium Myxococcus xanthus	12
Magneto-responsive hyaluronan hydrogel for hyperthermia and bioprinting: Magnetic, rheological properties and biocompatibility	12
Opto-electromechanical quantification of epithelial barrier function in injured and healthy airway tissues	12
PEDOT:PSS-coated platinum electrodes for neural stimulation	10
A novel portable in situ printer for hydrogel multi-structure molding and cell printing	10
Editorial Series conclusion and journal outlook	10
Nuclear mechanoprotection: From tissue atlases as blueprints to distinctive regulation of nuclear lamins	10
Functional hydrogels for diabetic wound management	10
Computational modeling of the physical features that influence breast cancer invasion into adipose tissue	9
Machine learning-informed predictions of nanoparticle mobility and fate in the mucus barrier	9
Topological defects in the mesothelium suppress ovarian cancer cell clearance	9
3D convolutional neural networks predict cellular metabolic pathway use from fluorescence lifetime decay data	9
Surface physical cues mediate the uptake of foreign particles by cancer cells	9
A high throughput cell stretch device for investigating mechanobiology in vitro	9
Gold nanorods with iron oxide dual-modal bioprobes in SERS-MRI enable accurate programmed cell death ligand-1 expression detection in triple-negative breast cancer	9
Biophysical and biochemical aspects of immune cell–tumor microenvironment interactions	9
Fibroblast senescence-associated extracellular matrix promotes heterogeneous lung niche	9
Investigating the reliability of the evoked response in human iPSCs-derived neuronal networks coupled to micro-electrode arrays	9
Mechanosensitive miR-99b mediates the regulatory effect of matrix stiffness on bone marrow mesenchymal stem cell fate both in vitro and in vivo	8

GelMA micropattern enhances cardiomyocyte organization, maturation, and contraction via contact guidance	8
Evaluation of chromatin mesoscale organization	8
Interacting with tumor cells weakens the intrinsic clockwise chirality of endothelial cells	8
Fabrication and characterizations of simvastatin-containing mesoporous bioactive glass and molybdenum disulfide scaffold for bone tissue engineering	8
User-friendly microfluidic system reveals native-like morphological and transcriptomic phenotypes induced by shear stress in proximal tubule epithelium	8
Application of machine learning in understanding atherosclerosis: Emerging insights	8