APL Bioengineering

Article	Citations
Adenine base editing rescues pathogenic phenotypes in tissue engineered vascular model of Hutchinson-Gilford progeria syndrome	75
A low-profile electromechanical packaging system for soft-to-flexible bioelectronic interfaces	63
Black phosphorus-enhanced injectable hydrogel for infected soft tissue healing	59
Thermosensitive hydrogel carrying extracellular vesicles from adipose-derived stem cells promotes peripheral nerve regeneration after microsurgical repair	55
Design and implementation of a microfluidic device capable of temporal growth factor delivery reveal filtering capabilities of the EGFR/ERK pathway	42
The yellow brick road to nuclear membrane mechanotransduction	35
Engineering CAR T cells for enhanced efficacy and safety	34
Scheduled dosage regimen by irreversible electroporation of loaded erythrocytes for cancer treatment	30
Aqueous electrolyte-gated solution-processed metal oxide transistors for direct cellular interfaces	30
Proteomics of human platelet lysates and insight from animal studies on platelet protein diffusion to hippocampus upon intranasal administration	30
Substrate stiffness modulates collective colony expansion of the social bacterium Myxococcus xanthus	29
GelMA micropattern enhances cardiomyocyte organization, maturation, and contraction via contact guidance	28
The mechanobiology of nuclear phase separation	28
Computational modeling of the physical features that influence breast cancer invasion into adipose tissue	24
Exploring the translational impact of type 1 diabetes on cerebral neurovascular function through ECoG-LSCI	24
A fully automated deep learning approach for coronary artery segmentation and comprehensive characterization	23
Fibroblast senescence-associated extracellular matrix promotes heterogeneous lung niche	22
Geometrically engineered organoid units and their assembly for pre-construction of organ structures	21
Erratum: “New contrast agents for photoacoustic imaging and theranostics: Recent 5-year overview on phthalocyanine/naphthalocyanine-based nanoparticles” [APL Bioeng. 5, 031510 (2021)]	21
Unpleasant odors compared to pleasant ones cause higher cortical activations detectable by fNIRS and observable mostly in females	21
Evaluation of chromatin mesoscale organization	21
A novel portable in situ printer for hydrogel multi-structure molding and cell printing	20
Machine learning-informed predictions of nanoparticle mobility and fate in the mucus barrier	20
Electrophysiological features of cortical 3D networks are deeply modulated by scaffold properties	19
Mechanism study on the influences of buffer osmotic pressure on microfluidic chip-based cell electrofusion	18

Learning discrete structures for cancer radiomics	18
Model discovery approach enables noninvasive measurement of intra-tumoral fluid transport in dynamic MRI	18
The role of biomechanical factors in models of intervertebral disc degeneration across multiple length scales	17
Degradation-aware neural imputation: Advancing decoding stability in brain machine interfaces	17
Non-contact radiofrequency stimulation to the olfactory nerve of human subjects	17
Orthopedic meta-implants	17
Advancements in textile techniques for cardiovascular tissue replacement and repair	16
Current state of the art and future directions for implantable sensors in medical technology: Clinical needs and engineering challenges	16
Immunogenic cell death-related cancer-associated fibroblast clusters and prognostic risk model in cervical cancer	16
Fluorescence spectroscopy as a novel tool in hematological diagnostics	16
Model of collective detachment in high-grade serous ovarian cancer demonstrates that tumor spheroids produce ECM to support metastatic processes	15
Terahertz in vivo imaging of human skin: Toward detection of abnormal skin pathologies	15
In vivo label-free tissue histology through a microstructured imaging window	15
M/EEG source localization for both subcortical and cortical sources using a convolutional neural network with a realistic head conductivity model	15
Differential effects of vascular endothelial growth factor on glycocalyx of endothelial and tumor cells and potential targets for tumor metastasis	14
Injectable photosensitive bone cement enhancing angiogenesis and osteogenic differentiation for the treatment of bone nonunion	14
Altered blood flow due to larger aortic diameters in patients with transcatheter heart valve thrombosis	14
Hyaluronic acid turnover controls the severity of cerebral cavernous malformations in bioengineered human micro-vessels	14
Advanced biomaterial strategies for overcoming age-associated wound healing impairments	14
TTLL4 mediates the PI3K/AKT/MDM2 pathway to promote hepatocellular carcinoma progression and predict patient prognosis	14
Regulation of airway remodeling in asthma: The synergistic effects of nanotechnology and Hippo pathway activation	13
Quercetin targets the Ccl4–Ccr5 axis to relieve neuropathic pain after spinal cord injury	13
A review: Blood pressure monitoring based on PPG and circadian rhythm	13
The effects of strain history on aortic valve interstitial cell activation in a 3D hydrogel environment	13
CAR T cell infiltration and cytotoxic killing within the core of 3D breast cancer spheroids under the control of antigen sensing in microwell arrays	13
Publisher's Note: “Contrast-enhanced ultrasound tracking of helical propellers with acoustic phase analysis and comparison with color Doppler” [APL Bioeng. 6, 036102 (2022)]	13
Bioengineering of the liver	12
Improvement of clinical wound microcirculation diagnosis using an object tracking-based laser speckle contrast imaging system	12
Mechanical cues orchestrate monocyte behavior in immune regulation and disease	12
Investigations on artificially extending the spectral range of natural vision	12
Single-cell RNA and bulk sequencing analysis reveals that formononetin inhibits GTSF1 to exert anti-osteosarcoma effects	12
Long-term effect of sodium selenite on the integrity and permeability of on-chip microvasculature	12
Fluid flow to mimic organ function in 3D in vitro models	12
Mechanobiology of the cell nucleus	11
Single-pericyte nanomechanics measured by contraction cytometry	11
Collagen density regulates tip–stalk cell rearrangement during angiogenesis via cellular bioenergetics	11
Biosensors integrated within wearable devices for monitoring chronic wound status	10
A patient-specific echogenic soft robotic left ventricle embedded into a closed-loop cardiovascular simulator for advanced device testing	10
FRESH™ 3D bioprinted cardiac tissue, a bioengineered platform for in vitro pharmacology	10
Hemodynamics of thrombus formation in intracranial aneurysms: An in silico observational study	10
Interacting with tumor cells weakens the intrinsic clockwise chirality of endothelial cells	10
Mechanosensitive miR-99b mediates the regulatory effect of matrix stiffness on bone marrow mesenchymal stem cell fate both in vitro and in vivo	10
Photoplethysmography-based HRV analysis and machine learning for real-time stress quantification in mental health applications	9
High-throughput quantitation of human neutrophil recruitment and functional responses in an air-blood barrier array	9
Engineered matrix microenvironments reveal the heterogeneity of liver sinusoidal endothelial cell phenotypic responses	9
Nuclear mechanoprotection: From tissue atlases as blueprints to distinctive regulation of nuclear lamins	9
A high throughput cell stretch device for investigating mechanobiology in vitro	9
PEDOT:PSS-coated platinum electrodes for neural stimulation	9
Rapid flowing cells localization enabled by spatiotemporal manipulation of their holographic patterns	9
Publisher's Note: “Skin-on-a-chip models: General overview and future perspectives” [APL Bioengineering 5, 030901 (2021)]	9

Modeling nitric oxide diffusion and plasticity modulation in cerebellar learning	9
Magnetic self-assembly of 3D multicellular microscaffolds: A biomimetic brain tumor-on-a-chip for drug delivery and selectivity testing	9
Cerebellar contribution to multisensory integration: A computational modeling exploration	9
Engineering approaches for understanding mechanical memory in cancer metastasis	8
Epigenetic regulation and mechanobiological adaptation in tenocytes during maturation	8
Publisher's Note: “Magneto-responsive hyaluronan hydrogel for hyperthermia and bioprinting: Magnetic, rheological properties and biocompatibility” [APL Bioeng. 7, 036113 (2023)]	8
Low-intensity pulsed ultrasound irradiation ameliorates gut inflammation and neuroinflammation in mice with DSS-induced colitis	8
Burst sine wave electroporation (B-SWE) for expansive blood–brain barrier disruption and controlled non-thermal tissue ablation for neurological disease	8
Survivin as a mediator of stiffness-induced cell cycle progression and proliferation of vascular smooth muscle cells	8
Stem cell mechanoadaptation. II. Microtubule stabilization and substrate compliance effects on cytoskeletal remodeling	8
Surface electromyography using dry polymeric electrodes	8
Nondestructive, quantitative viability analysis of 3D tissue cultures using machine learning image segmentation	8
Hepatocyte cultures: From collagen gel sandwiches to microfluidic devices with integrated biosensors	8
3D photopolymerized microstructured scaffolds influence nuclear deformation, nucleo/cytoskeletal protein organization, and gene regulation in mesenchymal stem cells	7
Mechanobiological engineering strategies for organoid culture	7
Drug/gene delivery and theranostics	7
Silk fibroin promotes H3K9me3 expression and chromatin reorganization to regulate endothelial cell proliferation	7
The mechanobiology of fibroblast activation in disease	7
Imaging of the vascular distribution of the outer ear using optical coherence tomography angiography for highly accurate positioning of a hearable sensor	7
All-in-one properties of an anticancer-covered airway stent for the prevention of malignant central airway obstruction	7
Generation of direct current electrical fields as regenerative therapy for spinal cord injury: A review	7
Investigating cartilage-related diseases by polarization-resolved second harmonic generation (P-SHG) imaging	7
Wearable devices for continuous monitoring of biosignals: Challenges and opportunities	7
Mutual antagonism between CD44 and integrins in glioblastoma cell traction and migration	7
GelMA-glycol chitosan hydrogels for cartilage regeneration: The role of uniaxial mechanical stimulation in enhancing mechanical, adhesive, and biochemical properties	7
Fluid shear stress induced-endothelial phenotypic transition contributes to cerebral ischemia–reperfusion injury and repair	7
Metronomic photodynamic therapy for deep organ cancer by implantable wireless OLEDs	7
Guest Editorial: Structure and mechanics of biofluids, biomaterials, and biologics	7
Long-term day-by-day tracking of microvascular networks sprouting in fibrin gels: From detailed morphological analyses to general growth rules	6
Finite element analysis of electric field distribution during direct current stimulation of the spinal cord: Implications for device design	6
Application of instant assembly of collagen to bioprint cardiac tissues	6
Three-dimensional matrix stiffness modulates mechanosensitive and phenotypic alterations in oral squamous cell carcinoma spheroids	6
On the nuclear pore complex and its emerging role in cellular mechanotransduction	6
Optimization frameworks for bespoke sensory encoding in neuroprosthetics	6
Studying the roles of salt ions in the pore initiation and closure stages in the biomembrane electroporation	6
Publisher's Note: “Finite element analysis of electric field distribution during direct current stimulation of the spinal cord: Implications for device design” [APL Bioeng. 7, 046109 (2023)]	6
Structure–function relationships for squid skin-inspired wearable thermoregulatory materials	6
A multi-scale numerical approach to study monoclonal antibodies in solution	6
IgG and IgM differentiation in a particle-based agglutination assay by control over antigen surface density	6
Mechanoimmunology: Are inflammatory epigenetic states of macrophages tuned by biophysical factors?	6
Computational pulmonary edema: A microvascular model of alveolar capillary and interstitial flow	6
Human gut epithelium features recapitulated in MINERVA 2.0 millifluidic organ-on-a-chip device	6
Immune checkpoint blockade enhances chemophototherapy in a syngeneic pancreatic tumor model	6
Multifunctional scaffolds for biomedical applications: Crafting versatile solutions with polycaprolactone enriched by graphene oxide	6
Editorial Series conclusion and journal outlook	5
Recent advancements in polymer science for retinal diseases: New frontiers in drug delivery systems	5
User-friendly microfluidic system reveals native-like morphological and transcriptomic phenotypes induced by shear stress in proximal tubule epithelium	5
AI-aided holographic flow cytometry for label-free identification of ovarian cancer cells in the presence of unbalanced datasets	5
Electrical aspects of skin as a pathway to engineering skin devices	5
Applying physical principles to cancer research	5
The effect of chronic kidney disease on tissue formation of in situ tissue-engineered vascular grafts	5
Publisher's Note: “Magnetic force-based cell manipulation for in vitro tissue engineering” [APL Bioeng. 7, 031504 (2023)]	5
A modular and reconfigurable microfluidic device for culturing spheroids under continuous perfusion	5
Gold nanorods with iron oxide dual-modal bioprobes in SERS-MRI enable accurate programmed cell death ligand-1 expression detection in triple-negative breast cancer	5
Functional analysis of human brain endothelium using a microfluidic device integrating a cell culture insert	5
Human pluripotent stem cell-derived cardiomyocytes align under cyclic strain when guided by cardiac fibroblasts	5
A fully implantable sensorized artificial urinary bladder to restore continence and fullness monitoring	5
Evaluation of screw pull-out from plate fixation of en bloc distal radius resection with ulnar reconstruction: Finite element analysis and comparison with experiments on Thiel cadavers	5
Peptide coacervates as intracellular delivery vehicles for synergistic cancer photothermal- and chemo-therapies	5
Decoding force-transmission linkages for therapeutic targeting and engineering	5
Highly stretchable and sensitive silicone composites with positive piezoconductivity using nickel powder and ionic liquid	5
3D confinement alters smooth muscle cell responses to chemical and mechanical cues	5
Magneto-responsive hyaluronan hydrogel for hyperthermia and bioprinting: Magnetic, rheological properties and biocompatibility	5
Investigating the reliability of the evoked response in human iPSCs-derived neuronal networks coupled to micro-electrode arrays	5
Survivin modulates stiffness-induced vascular smooth muscle cell motility	5
Long-acting acid-sensitive ketal-linked dexamethasone microcrystals for treating experimental autoimmune uveitis	5
Hydrodynamic efficient cell capture and pairing method on microfluidic cell electrofusion chip	5
Apoptosis-associated genetic mechanisms in the transition from rheumatoid arthritis to osteoporosis: A bioinformatics and functional analysis approach	5
Elastocapillary effects determine early matrix deformation by glioblastoma cell spheroids	4
Different contractility modes control cell escape from multicellular spheroids and tumor explants	4
Use of mesoporous polydopamine nanoparticles as a stable drug-release system alleviates inflammation in knee osteoarthritis	4
In situ single-molecule investigations of the impacts of biochemical perturbations on conformational intermediates of monomeric α-synuclein	4
Multicompartment duct platform to study epithelial–endothelial crosstalk associated with lung adenocarcinoma	4
Parallel on-chip micropipettes enabling quantitative multiplexed characterization of vesicle mechanics and cell aggregates rheology	4
Post-stroke spontaneous motor recovery in mice can be predicted from acute-phase local field potential using machine learning	4
Mechanotransduction for therapeutic approaches: Cellular aging and rejuvenation	4
Review of robotic systems for thoracoabdominal puncture interventional surgery	4
Osteogenically committed hUCMSCs-derived exosomes promote the recovery of critical-sized bone defects with enhanced osteogenic properties	4
Enhanced non-viral gene delivery via calcium phosphate/DNA co-precipitates with low-voltage pulse electroporation in NK-92 cells for immunocellular therapy	4
Possibilities in bioelectronics: Super humans or science fiction?	4

Recent progress in electrospun nanomaterials for wearables	4
Programmed wound healing in aged skin may be enhanced by mesenchymal cell loaded gene-activated scaffolds	4
Polarized macrophages modulate cardiac structure and contractility under hypoxia in novel immuno-heart on a chip	4
Electrodynamic interaction between tumor treating fields and microtubule electrophysiological activities	3
Engineered tissue geometry and Plakophilin-2 regulate electrophysiology of human iPSC-derived cardiomyocytes	3
Advancing hyperspectral imaging and machine learning tools toward clinical adoption in tissue diagnostics: A comprehensive review	3
Heterojunction semiconductor nanocatalysts as cancer theranostics	3
Effects of forces on chromatin	3
Biophysical and biochemical aspects of immune cell–tumor microenvironment interactions	3
Emerging mechanomedicines informed by mechanotransduction along the integrin–cytoskeleton–nucleus axis	3
Testing mixing rules for structural and dynamical quantities in multi-component crowded protein solutions	3
Oscillatory shear stress-induced downregulation of TET1s injures vascular endothelial planar cell polarity by suppression of actin polymerization	3
Biophysical perspectives to understanding cancer-associated fibroblasts	3
Memory in repetitive protein–protein interaction series	3
Self-organizing behaviors of cardiovascular cells on synthetic nanofiber scaffolds	3
Photothermal therapy using graphene quantum dots	3
Gut-on-a-chip models for dissecting the gut microbiology and physiology	3
Multi-actuator light-controlled biological robots	3
Insights into the mechanobiology of cancer metastasis via microfluidic technologies	3
Epigenetic dynamics in meniscus cell migration and its zonal dependency in response to inflammatory conditions	3
Nuclear lamins: Structure and function in mechanobiology	3
Functional biomaterials	3
Retraction: “Computational pulmonary edema: A microvascular model of alveolar capillary and interstitial flow” [APL Bioeng. 6, 046104 (2022)]	3
Interstitial fluid flow in an engineered human lymph node stroma model modulates T cell egress and stromal change	3
Magnetic force-based cell manipulation for in vitro tissue engineering	3
Asymmetrical positioning of cell organelles reflects the cell chirality of mouse myoblast cells	3
Fluid shear stress enhances natural killer cell's cytotoxicity toward circulating tumor cells through NKG2D-mediated mechanosensing	3
Frequency and duration of sensory flicker control transcriptional profiles in 5xFAD mice	3
Contrast-enhanced ultrasound tracking of helical propellers with acoustic phase analysis and comparison with color Doppler	3
Revisiting tissue tensegrity: Biomaterial-based approaches to measure forces across length scales	3
4D Light-sheet imaging and interactive analysis of cardiac contractility in zebrafish larvae	3