APL Bioengineering

Article	Citations
A low-profile electromechanical packaging system for soft-to-flexible bioelectronic interfaces	89
Synergy between photonics and biological approaches—A review of combination therapies for cancer theranostics	84
Adenine base editing rescues pathogenic phenotypes in tissue engineered vascular model of Hutchinson-Gilford progeria syndrome	76
Aqueous electrolyte-gated solution-processed metal oxide transistors for direct cellular interfaces	71
Substrate stiffness modulates collective colony expansion of the social bacterium Myxococcus xanthus	41
Thermosensitive hydrogel carrying extracellular vesicles from adipose-derived stem cells promotes peripheral nerve regeneration after microsurgical repair	40
Engineering CAR T cells for enhanced efficacy and safety	40
Black phosphorus-enhanced injectable hydrogel for infected soft tissue healing	33
The yellow brick road to nuclear membrane mechanotransduction	33
Scheduled dosage regimen by irreversible electroporation of loaded erythrocytes for cancer treatment	32
Proteomics of human platelet lysates and insight from animal studies on platelet protein diffusion to hippocampus upon intranasal administration	32
Evaluation of chromatin mesoscale organization	28
Electrophysiological features of cortical 3D networks are deeply modulated by scaffold properties	28
Computational modeling of the physical features that influence breast cancer invasion into adipose tissue	28
Exploring the translational impact of type 1 diabetes on cerebral neurovascular function through ECoG-LSCI	27
3D bioprinted human iPSC-derived neural progenitor cells as a novel platform for studying neurogenic niche	27
Geometrically engineered organoid units and their assembly for pre-construction of organ structures	26
Unpleasant odors compared to pleasant ones cause higher cortical activations detectable by fNIRS and observable mostly in females	24
The mechanobiology of nuclear phase separation	23
GelMA micropattern enhances cardiomyocyte organization, maturation, and contraction via contact guidance	23
Fibroblast senescence-associated extracellular matrix promotes heterogeneous lung niche	22
Machine learning-informed predictions of nanoparticle mobility and fate in the mucus barrier	22
A novel portable in situ printer for hydrogel multi-structure molding and cell printing	22
Model discovery approach enables noninvasive measurement of intra-tumoral fluid transport in dynamic MRI	21
Degradation-aware neural imputation: Advancing decoding stability in brain machine interfaces	21

A fully automated deep learning approach for coronary artery segmentation and comprehensive characterization	21
Learning discrete structures for cancer radiomics	21
A comprehensive review of graphene-based biosensors: Fabrication, applications, characterization and future perspectives—A review	20
Non-contact radiofrequency stimulation to the olfactory nerve of human subjects	20
Current state of the art and future directions for implantable sensors in medical technology: Clinical needs and engineering challenges	20
Orthopedic meta-implants	19
M/EEG source localization for both subcortical and cortical sources using a convolutional neural network with a realistic head conductivity model	18
The role of biomechanical factors in models of intervertebral disc degeneration across multiple length scales	18
Advancements in textile techniques for cardiovascular tissue replacement and repair	18
Mechanism study on the influences of buffer osmotic pressure on microfluidic chip-based cell electrofusion	18
Formononetin suppresses osteosarcoma by targeting MYO1B and remodeling the tumor immune microenvironment	18
Immunogenic cell death-related cancer-associated fibroblast clusters and prognostic risk model in cervical cancer	17
Tissue regenerative medicine: Clinical advances, challenges, and opportunities	17
Model of collective detachment in high-grade serous ovarian cancer demonstrates that tumor spheroids produce ECM to support metastatic processes	16
Fluorescence spectroscopy as a novel tool in hematological diagnostics	16
Terahertz in vivo imaging of human skin: Toward detection of abnormal skin pathologies	16
Digital light processing of hydrogel molds to guide cell mechanosensing and the fabrication of meniscal tissue constructs	15
Advanced biomaterial strategies for overcoming age-associated wound healing impairments	15
Altered blood flow due to larger aortic diameters in patients with transcatheter heart valve thrombosis	15
TTLL4 mediates the PI3K/AKT/MDM2 pathway to promote hepatocellular carcinoma progression and predict patient prognosis	15
Regulation of airway remodeling in asthma: The synergistic effects of nanotechnology and Hippo pathway activation	15
Differential effects of vascular endothelial growth factor on glycocalyx of endothelial and tumor cells and potential targets for tumor metastasis	14
Injectable photosensitive bone cement enhancing angiogenesis and osteogenic differentiation for the treatment of bone nonunion	14
A review: Blood pressure monitoring based on PPG and circadian rhythm	14
Mechanical cues orchestrate monocyte behavior in immune regulation and disease	13
Long-term effect of sodium selenite on the integrity and permeability of on-chip microvasculature	13
Bioengineering of the liver	13
Hyaluronic acid turnover controls the severity of cerebral cavernous malformations in bioengineered human micro-vessels	13
The effects of strain history on aortic valve interstitial cell activation in a 3D hydrogel environment	13
Improvement of clinical wound microcirculation diagnosis using an object tracking-based laser speckle contrast imaging system	13
In vivo label-free tissue histology through a microstructured imaging window	13
CAR T cell infiltration and cytotoxic killing within the core of 3D breast cancer spheroids under the control of antigen sensing in microwell arrays	13
Publisher's Note: “Contrast-enhanced ultrasound tracking of helical propellers with acoustic phase analysis and comparison with color Doppler” [APL Bioeng. 6, 036102 (2022)]	13
Quercetin targets the Ccl4–Ccr5 axis to relieve neuropathic pain after spinal cord injury	12
A patient-specific echogenic soft robotic left ventricle embedded into a closed-loop cardiovascular simulator for advanced device testing	12
Fluid flow to mimic organ function in 3D in vitro models	12
Single-cell RNA and bulk sequencing analysis reveals that formononetin inhibits GTSF1 to exert anti-osteosarcoma effects	12
Investigations on artificially extending the spectral range of natural vision	12
Photoplethysmography-based HRV analysis and machine learning for real-time stress quantification in mental health applications	11
A high throughput cell stretch device for investigating mechanobiology in vitro	11
Mechanobiology of the cell nucleus	11
Collagen density regulates tip–stalk cell rearrangement during angiogenesis via cellular bioenergetics	11
Magnetic self-assembly of 3D multicellular microscaffolds: A biomimetic brain tumor-on-a-chip for drug delivery and selectivity testing	11
FRESH™ 3D bioprinted cardiac tissue, a bioengineered platform for in vitro pharmacology	11
Single-pericyte nanomechanics measured by contraction cytometry	11
Hemodynamics of thrombus formation in intracranial aneurysms: An in silico observational study	11
Interacting with tumor cells weakens the intrinsic clockwise chirality of endothelial cells	11
Biosensors integrated within wearable devices for monitoring chronic wound status	11
Publisher's Note: “Magneto-responsive hyaluronan hydrogel for hyperthermia and bioprinting: Magnetic, rheological properties and biocompatibility” [APL Bioeng. 7, 036113 (2023)]	10
Modeling nitric oxide diffusion and plasticity modulation in cerebellar learning	10

Cerebellar contribution to multisensory integration: A computational modeling exploration	10
Engineered matrix microenvironments reveal the heterogeneity of liver sinusoidal endothelial cell phenotypic responses	10
Rapid flowing cells localization enabled by spatiotemporal manipulation of their holographic patterns	10
High-throughput quantitation of human neutrophil recruitment and functional responses in an air-blood barrier array	10
PEDOT:PSS-coated platinum electrodes for neural stimulation	10
Epigenetic regulation and mechanobiological adaptation in tenocytes during maturation	10
Burst sine wave electroporation (B-SWE) for expansive blood–brain barrier disruption and controlled non-thermal tissue ablation for neurological disease	10
Nuclear mechanoprotection: From tissue atlases as blueprints to distinctive regulation of nuclear lamins	10
Mechanosensitive miR-99b mediates the regulatory effect of matrix stiffness on bone marrow mesenchymal stem cell fate both in vitro and in vivo	10
Nondestructive, quantitative viability analysis of 3D tissue cultures using machine learning image segmentation	10
Surface electromyography using dry polymeric electrodes	10
Imaging of the vascular distribution of the outer ear using optical coherence tomography angiography for highly accurate positioning of a hearable sensor	9
All-in-one properties of an anticancer-covered airway stent for the prevention of malignant central airway obstruction	9
GelMA-glycol chitosan hydrogels for cartilage regeneration: The role of uniaxial mechanical stimulation in enhancing mechanical, adhesive, and biochemical properties	9
Engineering approaches for understanding mechanical memory in cancer metastasis	9
Low-intensity pulsed ultrasound irradiation ameliorates gut inflammation and neuroinflammation in mice with DSS-induced colitis	9
3D photopolymerized microstructured scaffolds influence nuclear deformation, nucleo/cytoskeletal protein organization, and gene regulation in mesenchymal stem cells	9
Mechanomedicine: Translating mechanical forces into therapeutic strategies	9
Stem cell mechanoadaptation. II. Microtubule stabilization and substrate compliance effects on cytoskeletal remodeling	9
Survivin as a mediator of stiffness-induced cell cycle progression and proliferation of vascular smooth muscle cells	9
Mutual antagonism between CD44 and integrins in glioblastoma cell traction and migration	9
Mechanobiological engineering strategies for organoid culture	8
Immune checkpoint blockade enhances chemophototherapy in a syngeneic pancreatic tumor model	8
The mechanobiology of fibroblast activation in disease	8
Drug/gene delivery and theranostics	8
Wearable devices for continuous monitoring of biosignals: Challenges and opportunities	8
Investigating cartilage-related diseases by polarization-resolved second harmonic generation (P-SHG) imaging	8
A multi-scale numerical approach to study monoclonal antibodies in solution	8
Guest Editorial: Structure and mechanics of biofluids, biomaterials, and biologics	8
Generation of direct current electrical fields as regenerative therapy for spinal cord injury: A review	8
Fluid shear stress induced-endothelial phenotypic transition contributes to cerebral ischemia–reperfusion injury and repair	8
Metronomic photodynamic therapy for deep organ cancer by implantable wireless OLEDs	8
Structure–function relationships for squid skin-inspired wearable thermoregulatory materials	8
Publisher's Note: “Finite element analysis of electric field distribution during direct current stimulation of the spinal cord: Implications for device design” [APL Bioeng. 7, 046109 (2023)]	8
Stiffness-mediated paracrine signaling enhances induction of EMT in oral squamous cell carcinoma	8
Silk fibroin promotes H3K9me3 expression and chromatin reorganization to regulate endothelial cell proliferation	8
Mechanoimmunology: Are inflammatory epigenetic states of macrophages tuned by biophysical factors?	7
Human gut epithelium features recapitulated in MINERVA 2.0 millifluidic organ-on-a-chip device	7
IgG and IgM differentiation in a particle-based agglutination assay by control over antigen surface density	7
Finite element analysis of electric field distribution during direct current stimulation of the spinal cord: Implications for device design	7
Highly stretchable and sensitive silicone composites with positive piezoconductivity using nickel powder and ionic liquid	7
Application of instant assembly of collagen to bioprint cardiac tissues	7
Computational pulmonary edema: A microvascular model of alveolar capillary and interstitial flow	7
Multifunctional scaffolds for biomedical applications: Crafting versatile solutions with polycaprolactone enriched by graphene oxide	7
Studying the roles of salt ions in the pore initiation and closure stages in the biomembrane electroporation	7
Investigating the reliability of the evoked response in human iPSCs-derived neuronal networks coupled to micro-electrode arrays	7
Three-dimensional matrix stiffness modulates mechanosensitive and phenotypic alterations in oral squamous cell carcinoma spheroids	7
Optimization frameworks for bespoke sensory encoding in neuroprosthetics	7
Magneto-responsive hyaluronan hydrogel for hyperthermia and bioprinting: Magnetic, rheological properties and biocompatibility	7
On the nuclear pore complex and its emerging role in cellular mechanotransduction	7
Long-term day-by-day tracking of microvascular networks sprouting in fibrin gels: From detailed morphological analyses to general growth rules	7
Publisher's Note: “Magnetic force-based cell manipulation for in vitro tissue engineering” [APL Bioeng. 7, 031504 (2023)]	6
Apoptosis-associated genetic mechanisms in the transition from rheumatoid arthritis to osteoporosis: A bioinformatics and functional analysis approach	6
Hydrodynamic efficient cell capture and pairing method on microfluidic cell electrofusion chip	6
A modular and reconfigurable microfluidic device for culturing spheroids under continuous perfusion	6
3D confinement alters smooth muscle cell responses to chemical and mechanical cues	6
Skin-on-chip: Quo vadis?	6
Peptide coacervates as intracellular delivery vehicles for synergistic cancer photothermal- and chemo-therapies	6
User-friendly microfluidic system reveals native-like morphological and transcriptomic phenotypes induced by shear stress in proximal tubule epithelium	6
Editorial Series conclusion and journal outlook	6
Evaluation of screw pull-out from plate fixation of en bloc distal radius resection with ulnar reconstruction: Finite element analysis and comparison with experiments on Thiel cadavers	6
Gold nanorods with iron oxide dual-modal bioprobes in SERS-MRI enable accurate programmed cell death ligand-1 expression detection in triple-negative breast cancer	6
Functional analysis of human brain endothelium using a microfluidic device integrating a cell culture insert	5
Recent advancements in polymer science for retinal diseases: New frontiers in drug delivery systems	5
Survivin modulates stiffness-induced vascular smooth muscle cell motility	5
Enhanced non-viral gene delivery via calcium phosphate/DNA co-precipitates with low-voltage pulse electroporation in NK-92 cells for immunocellular therapy	5
Prediction of chronic obstructive pulmonary disease based on multimodal data and deep learning	5
Different contractility modes control cell escape from multicellular spheroids and tumor explants	5
Long-acting acid-sensitive ketal-linked dexamethasone microcrystals for treating experimental autoimmune uveitis	5
The effect of chronic kidney disease on tissue formation of in situ tissue-engineered vascular grafts	5
Decoding force-transmission linkages for therapeutic targeting and engineering	5
Post-stroke spontaneous motor recovery in mice can be predicted from acute-phase local field potential using machine learning	5
Mechanotransduction for therapeutic approaches: Cellular aging and rejuvenation	5
Recent progress in electrospun nanomaterials for wearables	5
Programmed wound healing in aged skin may be enhanced by mesenchymal cell loaded gene-activated scaffolds	5
A fully implantable sensorized artificial urinary bladder to restore continence and fullness monitoring	5
AI-aided holographic flow cytometry for label-free identification of ovarian cancer cells in the presence of unbalanced datasets	5
Elastocapillary effects determine early matrix deformation by glioblastoma cell spheroids	5
Human pluripotent stem cell-derived cardiomyocytes align under cyclic strain when guided by cardiac fibroblasts	5
Parallel on-chip micropipettes enabling quantitative multiplexed characterization of vesicle mechanics and cell aggregates rheology	5

Use of mesoporous polydopamine nanoparticles as a stable drug-release system alleviates inflammation in knee osteoarthritis	5
Applying physical principles to cancer research	5
Polarized macrophages modulate cardiac structure and contractility under hypoxia in novel immuno-heart on a chip	4
Multi-actuator light-controlled biological robots	4
Oscillatory shear stress-induced downregulation of TET1s injures vascular endothelial planar cell polarity by suppression of actin polymerization	4
Advancing hyperspectral imaging and machine learning tools toward clinical adoption in tissue diagnostics: A comprehensive review	4
Retraction: “Computational pulmonary edema: A microvascular model of alveolar capillary and interstitial flow” [APL Bioeng. 6, 046104 (2022)]	4
Finger joint angle and gesture estimation under natural conditions with a soft printed electrode array	4
Frequency and duration of sensory flicker control transcriptional profiles in 5xFAD mice	4
Asymmetrical positioning of cell organelles reflects the cell chirality of mouse myoblast cells	4
Multicompartment duct platform to study epithelial–endothelial crosstalk associated with lung adenocarcinoma	4
Osteogenically committed hUCMSCs-derived exosomes promote the recovery of critical-sized bone defects with enhanced osteogenic properties	4
Review of robotic systems for thoracoabdominal puncture interventional surgery	4
Assessing human scalp and brain blood flow sensitivities via superficial temporal artery occlusion using speckle contrast optical spectroscopy	4
Subject-specific multivariate modeling for regenerative rehabilitation of bone healing	4
4D Light-sheet imaging and interactive analysis of cardiac contractility in zebrafish larvae	4
In situ single-molecule investigations of the impacts of biochemical perturbations on conformational intermediates of monomeric α-synuclein	4