OOIR: Observatory of International Research

Papers

(The median citation count of APL Bioengineering is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-04-01 to 2024-04-01.)

Article	Citations
The rheology of direct and suspended extrusion bioprinting	129
Emergence of FRESH 3D printing as a platform for advanced tissue biofabrication	118
Recent advances on polymeric hydrogels as wound dressings	82
Artificial intelligence for brain diseases: A systematic review	78
Electrospinning and emerging healthcare and medicine possibilities	67
Biohybrid robot with skeletal muscle tissue covered with a collagen structure for moving in air	52
Functional hydrogels for diabetic wound management	51
Microglia-targeting nanotherapeutics for neurodegenerative diseases	50
Skin-on-a-chip models: General overview and future perspectives	49
Evaluation of current diagnostic methods for COVID-19	49
Complex 3D bioprinting methods	48
Sex differences in the blood–brain barrier and neurodegenerative diseases	45
Cell shape, and not 2D migration, predicts extracellular matrix-driven 3D cell invasion in breast cancer	40
Recent advancements in enzyme-mediated crosslinkable hydrogels: In vivo-mimicking strategies	39
Wearable devices for continuous monitoring of biosignals: Challenges and opportunities	37
A novel method to make viscoelastic polyacrylamide gels for cell culture and traction force microscopy	36
The effects of surface topography modification on hydrogel properties	32
Nanoerythrosome-functionalized biohybrid microswimmers	32
Mind the gap: State-of-the-art technologies and applications for EEG-based brain–computer interfaces	30
Cyclic tangential flow filtration system for isolation of extracellular vesicles	30
Toward improved in vitro models of human cancer	30
Nuclear lamins: Structure and function in mechanobiology	29
New contrast agents for photoacoustic imaging and theranostics: Recent 5-year overview on phthalocyanine/naphthalocyanine-based nanoparticles	27
Fundamentals of light-cell–polymer interactions in photo-cross-linking based bioprinting	27
Functional hydrogel bioink, a key challenge of 3D cellular bioprinting	26

Peptide functionalized liposomes for receptor targeted cancer therapy	25
Biomaterials-based formulations and surfaces to combat viral infectious diseases	24
Fluorescence strategies for mapping cell membrane dynamics and structures	24
Brain-on-a-Chip: Characterizing the next generation of advanced in vitro platforms for modeling the central nervous system	23
Atomic force microscopy—A tool for structural and translational DNA research	23
Surface engineering at the nanoscale: A way forward to improve coronary stent efficacy	22
Cell biomechanics and mechanobiology in bacteria: Challenges and opportunities	21
Stimuli-responsive biomaterials for cardiac tissue engineering and dynamic mechanobiology	21
Reconstituting the dynamics of endothelial cells and fibroblasts in wound closure	21
Microrheology for biomaterial design	20
Liver–Heart on chip models for drug safety	20
Injectable, macroporous scaffolds for delivery of therapeutic genes to the injured spinal cord	19
Emerging applications at the interface of DNA nanotechnology and cellular membranes: Perspectives from biology, engineering, and physics	19
An organosynthetic soft robotic respiratory simulator	18
Biofabrication of tissue engineering vascular systems	18
Effects of forces on chromatin	18
Implantable biorobotic organs	18
Emergence of functional neuromuscular junctions in an engineered, multicellular spinal cord-muscle bioactuator	18
A survey of physical methods for studying nuclear mechanics and mechanobiology	18
Microfluidic techniques for isolation, formation, and characterization of circulating tumor cells and clusters	18
Remodeling of an in vitro microvessel exposed to cyclic mechanical stretch	17
3D bioprinting of stem cell-laden cardiac patch: A promising alternative for myocardial repair	17
Principles for the design of multicellular engineered living systems	17
On the nuclear pore complex and its emerging role in cellular mechanotransduction	16
Mechanotransduction assays for neural regeneration strategies: A focus on glial cells	16
Engineering in vitro human neural tissue analogs by 3D bioprinting and electrostimulation	15
Modeling the tumor immune microenvironment for drug discovery using 3D culture	15
The mechanobiology of nuclear phase separation	15
Transforming a well into a chip: A modular 3D-printed microfluidic chip	15
Voltage-gated ion channels mediate the electrotaxis of glioblastoma cells in a hybrid PMMA/PDMS microdevice	15
Viscous shaping of the compliant cell nucleus	14
Application of machine learning in understanding atherosclerosis: Emerging insights	14
Recent progress in electrospun nanomaterials for wearables	14
Engineering CAR T cells for enhanced efficacy and safety	14
Electrical aspects of skin as a pathway to engineering skin devices	14
Microarrayed human bone marrow organoids for modeling blood stem cell dynamics	13
Engineering skeletal muscle tissues with advanced maturity improves synapse formation with human induced pluripotent stem cell-derived motor neurons	13
New insights into the biomimetic design and biomedical applications of bioengineered bone microenvironments	13
Controlled 3D co-culture of beta cells and endothelial cells in a micropatterned collagen sheet for reproducible construction of an improved pancreatic pseudo-tissue	12
Organ-on-a-disc: A platform technology for the centrifugal generation and culture of microphysiological 3D cell constructs amenable for automation and parallelization	12
Cell chirality in cardiovascular development and disease	12
Hepatocyte cultures: From collagen gel sandwiches to microfluidic devices with integrated biosensors	11
Topological defects in the mesothelium suppress ovarian cancer cell clearance	11
Label-free photoacoustic and ultrasound imaging for murine atherosclerosis characterization	11
Revisiting tissue tensegrity: Biomaterial-based approaches to measure forces across length scales	11
High-throughput screening of nanoparticles in drug delivery	11
Harnessing adipose stem cell diversity in regenerative medicine	11
Neovascularization of engineered tissues for clinical translation: Where we are, where we should be?	11
Tissue engineered endometrial barrier exposed to peristaltic flow shear stresses	10
Emerging roles of platelet concentrates and platelet-derived extracellular vesicles in regenerative periodontology and implant dentistry	10

Bacterial biomechanics—From individual behaviors to biofilm and the gut flora	10
Time dependent stress relaxation and recovery in mechanically strained 3D microtissues	10
Quantification and classification of potassium and calcium disorders with the electrocardiogram: What do clinical studies, modeling, and reconstruction tell us?	9
In silico models for evaluating proarrhythmic risk of drugs	9
Tailoring inkjet-printed PEDOT:PSS composition toward green, wearable device fabrication	9
Computational models of migration modes improve our understanding of metastasis	9
Magnetic self-assembly of 3D multicellular microscaffolds: A biomimetic brain tumor-on-a-chip for drug delivery and selectivity testing	9
Bioengineering the neurovascular niche to study the interaction of neural stem cells and endothelial cells	9
Replace and repair: Biomimetic bioprinting for effective muscle engineering	9
Microtechnology-based in vitro models: Mimicking liver function and pathophysiology	9
Progress in mimicking brain microenvironments to understand and treat neurological disorders	9
Functional bionanomaterials for cell surface engineering in cancer immunotherapy	8
Optimal low-intensity pulsed ultrasound stimulation for promoting anti-inflammatory effects in macrophages	8
Spectral CT imaging of human osteoarthritic cartilage via quantitative assessment of glycosaminoglycan content using multiple contrast agents	8
Latest impact of engineered human liver platforms on drug development	8
Nuclear mechanoprotection: From tissue atlases as blueprints to distinctive regulation of nuclear lamins	8
Dermal fibroblasts and triple-negative mammary epithelial cancer cells differentially stiffen their local matrix	8
Investigation of the hepatic development in the coculture of hiPSCs-derived LSECs and HLCs in a fluidic microenvironment	8
Nanosized drug delivery strategies in osteosarcoma chemotherapy	8
Leveraging multimodal microscopy to optimize deep learning models for cell segmentation	8
Prolonged recovery of 3D printed, photo-cured polylactide shape memory polymer networks	8
Stiffness based enrichment of leukemia cells using microfluidics	7
Differential effects of vascular endothelial growth factor on glycocalyx of endothelial and tumor cells and potential targets for tumor metastasis	7
Sweat analysis with a wearable sensing platform based on laser-induced graphene	7
Biomaterials for enhanced immunotherapy	7
Correcting anisotropic intensity in light sheet images using dehazing and image morphology	7
Cysteine cathepsins are altered by flow within an engineered in vitro microvascular niche	7
Integrating functional vasculature into organoid culture: A biomechanical perspective	7
The accumulation of particles in ureteric stents is mediated by flow dynamics: Full-scale computational and experimental modeling of the occluded and unoccluded ureter	6
Use of mesoporous polydopamine nanoparticles as a stable drug-release system alleviates inflammation in knee osteoarthritis	6
Functional analysis of human brain endothelium using a microfluidic device integrating a cell culture insert	6
A neuronal wiring platform through microridges for rationally engineered neural circuits	6
Machine learning based approach to pH imaging and classification of single cancer cells	6
Multi-actuator light-controlled biological robots	6
Toward improved models of human cancer	6
Biohybrid systems: Borrowing from nature to make better machines	6
Cardiovascular patient-specific modeling: Where are we now and what does the future look like?	6
Thermosensitive hydrogel carrying extracellular vesicles from adipose-derived stem cells promotes peripheral nerve regeneration after microsurgical repair	6
The role of mechanobiology in bone and cartilage model systems in characterizing initiation and progression of osteoarthritis	6
Understanding the role of mechanics in nucleocytoplasmic transport	6
Possibilities in bioelectronics: Super humans or science fiction?	6
Glutathione-sensitive nanoparticles enhance the combined therapeutic effect of checkpoint kinase 1 inhibitor and cisplatin in prostate cancer	6
Gut-on-a-chip models for dissecting the gut microbiology and physiology	6
Black phosphorus-enhanced injectable hydrogel for infected soft tissue healing	6
A suspended layer additive manufacturing approach to the bioprinting of tri-layered skin equivalents	5
Long-acting acid-sensitive ketal-linked dexamethasone microcrystals for treating experimental autoimmune uveitis	5
Retrospective clinical trial experimentally validates glioblastoma genome-wide pattern of DNA copy-number alterations predictor of survival	5
Mechanobiology of the cell nucleus	5
Immune checkpoint blockade enhances chemophototherapy in a syngeneic pancreatic tumor model	5
The role of biomechanical factors in models of intervertebral disc degeneration across multiple length scales	5
Machine learning-informed predictions of nanoparticle mobility and fate in the mucus barrier	5
Fluid flow to mimic organ function in 3D in vitro models	5
An optimal control approach for enhancing natural killer cells' secretion of cytolytic molecules	5
Advances in imaging and treatment of atherosclerosis based on organic nanoparticles	5
Photothermal therapy using graphene quantum dots	4
Remote neurostimulation with physical fields at cellular level enabled by nanomaterials: Toward medical applications	4
Engineered matrix microenvironments reveal the heterogeneity of liver sinusoidal endothelial cell phenotypic responses	4
Fluid shear stress enhances natural killer cell's cytotoxicity toward circulating tumor cells through NKG2D-mediated mechanosensing	4
Design and implementation of a microfluidic device capable of temporal growth factor delivery reveal filtering capabilities of the EGFR/ERK pathway	4
pH/thermal dual-responsive multifunctional drug delivery system for effective photoacoustic imaging-guided tumor chemo/photothermal therapy	4
Development of resveratrol with thiolated alginate as a supplement to prevent nonalcoholic fatty liver disease (NAFLD)	4
Mechanosensitive miR-99b mediates the regulatory effect of matrix stiffness on bone marrow mesenchymal stem cell fate both in vitro and in vivo	4
Mechanoimmunology: Are inflammatory epigenetic states of macrophages tuned by biophysical factors?	4
Functional biomaterials	4
Bioengineering platforms for cell therapeutics derived from pluripotent and direct reprogramming	4
A scalable 3D tissue culture pipeline to enable functional therapeutic screening for pulmonary fibrosis	4
Evaluation of chromatin mesoscale organization	4
Toward improved models of human cancer: Two perspectives	4