OOIR: Observatory of International Research

Papers

(The median citation count of APL Bioengineering is 6. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 500 papers]. The publications cover those that have been published in the past four years, i.e., from 2019-08-01 to 2023-08-01.)

Article	Citations
The rheology of direct and suspended extrusion bioprinting	87
Emergence of FRESH 3D printing as a platform for advanced tissue biofabrication	86
The rationale and emergence of electroconductive biomaterial scaffolds in cardiac tissue engineering	68
Recent advances on polymeric hydrogels as wound dressings	67
Label-free microfluidic sorting of microparticles	57
Artificial intelligence for brain diseases: A systematic review	56
Balance of interstitial flow magnitude and vascular endothelial growth factor concentration modulates three-dimensional microvascular network formation	52
Electrospinning and emerging healthcare and medicine possibilities	49
Evaluation of current diagnostic methods for COVID-19	47
Biohybrid robot with skeletal muscle tissue covered with a collagen structure for moving in air	39
Skin-on-a-chip models: General overview and future perspectives	38
Microfluidics-based skin irritation test using in vitro 3D angiogenesis platform	38
Sex differences in the blood–brain barrier and neurodegenerative diseases	37
3D bioprinting and its potential impact on cardiac failure treatment: An industry perspective	35
Complex 3D bioprinting methods	35
Development of 3D neuromuscular bioactuators	34
Microglia-targeting nanotherapeutics for neurodegenerative diseases	33
Cell shape, and not 2D migration, predicts extracellular matrix-driven 3D cell invasion in breast cancer	32
Functional hydrogels for diabetic wound management	32
Mechanical changes of peripheral nerve tissue microenvironment and their structural basis during development	31
Sonification based de novo protein design using artificial intelligence, structure prediction, and analysis using molecular modeling	29
Occlusive thrombosis in arteries	28
Nanoerythrosome-functionalized biohybrid microswimmers	27
Microfluidic platform for three-dimensional cell culture under spatiotemporal heterogeneity of oxygen tension	27
Recent advancements in enzyme-mediated crosslinkable hydrogels: In vivo-mimicking strategies	26

Toward improved in vitro models of human cancer	25
Cyclic tangential flow filtration system for isolation of extracellular vesicles	25
Addressing present pitfalls in 3D printing for tissue engineering to enhance future potential	25
A novel method to make viscoelastic polyacrylamide gels for cell culture and traction force microscopy	24
Mind the gap: State-of-the-art technologies and applications for EEG-based brain–computer interfaces	22
Fluorescence strategies for mapping cell membrane dynamics and structures	22
Biomaterials-based formulations and surfaces to combat viral infectious diseases	21
The effects of surface topography modification on hydrogel properties	21
Fundamentals of light-cell–polymer interactions in photo-cross-linking based bioprinting	20
Wearable devices for continuous monitoring of biosignals: Challenges and opportunities	20
New contrast agents for photoacoustic imaging and theranostics: Recent 5-year overview on phthalocyanine/naphthalocyanine-based nanoparticles	19
AAV-mediated gene therapy targeting TRPV4 mechanotransduction for inhibition of pulmonary vascular leakage	19
Peptide functionalized liposomes for receptor targeted cancer therapy	18
Reconstituting the dynamics of endothelial cells and fibroblasts in wound closure	18
Microrheology for biomaterial design	18
Functional hydrogel bioink, a key challenge of 3D cellular bioprinting	18
Photolithographic shape control of DNA hydrogels by photo-activated self-assembly of DNA nanostructures	17
Atomic force microscopy—A tool for structural and translational DNA research	17
Emerging trends in modeling human liver disease in vitro	17
Nuclear lamins: Structure and function in mechanobiology	17
Brain-on-a-Chip: Characterizing the next generation of advanced in vitro platforms for modeling the central nervous system	17
Microphysiological systems modeling acute respiratory distress syndrome that capture mechanical force-induced injury-inflammation-repair	16
Stimuli-responsive biomaterials for cardiac tissue engineering and dynamic mechanobiology	16
Emergence of functional neuromuscular junctions in an engineered, multicellular spinal cord-muscle bioactuator	16
Emerging applications at the interface of DNA nanotechnology and cellular membranes: Perspectives from biology, engineering, and physics	16
Liver–Heart on chip models for drug safety	16
An organosynthetic soft robotic respiratory simulator	15
Surface engineering at the nanoscale: A way forward to improve coronary stent efficacy	15
Cell biomechanics and mechanobiology in bacteria: Challenges and opportunities	15
Remodeling of an in vitro microvessel exposed to cyclic mechanical stretch	15
Endothelial mechanobiology	15
Analysis of mitral valve regurgitation by computational fluid dynamics	15
3D bioprinting of stem cell-laden cardiac patch: A promising alternative for myocardial repair	14
Injectable, macroporous scaffolds for delivery of therapeutic genes to the injured spinal cord	14
Mechanotransduction assays for neural regeneration strategies: A focus on glial cells	14
Implantable biorobotic organs	14
Effects of forces on chromatin	13
Application of machine learning in understanding atherosclerosis: Emerging insights	13
Disease-directed engineering for physiology-driven treatment interventions in neurological disorders	12
Microfiber-shaped building-block tissues with endothelial networks for constructing macroscopic tissue assembly	12
Voltage-gated ion channels mediate the electrotaxis of glioblastoma cells in a hybrid PMMA/PDMS microdevice	12
Organ-on-a-disc: A platform technology for the centrifugal generation and culture of microphysiological 3D cell constructs amenable for automation and parallelization	12
Biofabrication of tissue engineering vascular systems	12
On the nuclear pore complex and its emerging role in cellular mechanotransduction	11
Engineering in vitro human neural tissue analogs by 3D bioprinting and electrostimulation	11
Modeling the tumor immune microenvironment for drug discovery using 3D culture	11
Transforming a well into a chip: A modular 3D-printed microfluidic chip	10
A survey of physical methods for studying nuclear mechanics and mechanobiology	10
Topological defects in the mesothelium suppress ovarian cancer cell clearance	10
A microfluidic platform for simultaneous quantification of oxygen-dependent viscosity and shear thinning in sickle cell blood	10

Engineering skeletal muscle tissues with advanced maturity improves synapse formation with human induced pluripotent stem cell-derived motor neurons	10
Viscous shaping of the compliant cell nucleus	10
Principles for the design of multicellular engineered living systems	10
GSVD- and tensor GSVD-uncovered patterns of DNA copy-number alterations predict adenocarcinomas survival in general and in response to platinum	10
Bioengineering the neurovascular niche to study the interaction of neural stem cells and endothelial cells	9
Cell chirality in cardiovascular development and disease	9
New insights into the biomimetic design and biomedical applications of bioengineered bone microenvironments	9
Microarrayed human bone marrow organoids for modeling blood stem cell dynamics	9
Electrical aspects of skin as a pathway to engineering skin devices	9
Neovascularization of engineered tissues for clinical translation: Where we are, where we should be?	9
Automated sensing and splitting of stem cell colonies on microraft arrays	9
Good advice for endothelial cells: Get in line, relax tension, and go with the flow	9
Label-free photoacoustic and ultrasound imaging for murine atherosclerosis characterization	8
Prolonged recovery of 3D printed, photo-cured polylactide shape memory polymer networks	8
Harnessing adipose stem cell diversity in regenerative medicine	8
Bacterial biomechanics—From individual behaviors to biofilm and the gut flora	8
Computational models of migration modes improve our understanding of metastasis	8
Microtechnology-based in vitro models: Mimicking liver function and pathophysiology	8
Controlled 3D co-culture of beta cells and endothelial cells in a micropatterned collagen sheet for reproducible construction of an improved pancreatic pseudo-tissue	7
Multi-scale cellular engineering: From molecules to organ-on-a-chip	7
Tissue engineered endometrial barrier exposed to peristaltic flow shear stresses	7
Correcting anisotropic intensity in light sheet images using dehazing and image morphology	7
Leveraging multimodal microscopy to optimize deep learning models for cell segmentation	7
In silico models for evaluating proarrhythmic risk of drugs	7
Time dependent stress relaxation and recovery in mechanically strained 3D microtissues	7
Replace and repair: Biomimetic bioprinting for effective muscle engineering	7
High-throughput screening of nanoparticles in drug delivery	7
The mechanobiology of nuclear phase separation	7
Quantitative evaluation of the impact of artificial cell adhesion via DNA hybridization on E-cadherin-mediated cell adhesion	7
Dermal fibroblasts and triple-negative mammary epithelial cancer cells differentially stiffen their local matrix	7
Spectral CT imaging of human osteoarthritic cartilage via quantitative assessment of glycosaminoglycan content using multiple contrast agents	7
Latest impact of engineered human liver platforms on drug development	7
Hepatocyte cultures: From collagen gel sandwiches to microfluidic devices with integrated biosensors	7
Revisiting tissue tensegrity: Biomaterial-based approaches to measure forces across length scales	7
Microfluidic techniques for isolation, formation, and characterization of circulating tumor cells and clusters	7
An inexpensive programmable optogenetic platform for controlled neuronal activation regimens in C. elegans	6
Guided vascularization in the rat heart leads to transient vessel patterning	6
Quantification and classification of potassium and calcium disorders with the electrocardiogram: What do clinical studies, modeling, and reconstruction tell us?	6
Emerging roles of platelet concentrates and platelet-derived extracellular vesicles in regenerative periodontology and implant dentistry	6
Functional bionanomaterials for cell surface engineering in cancer immunotherapy	6
Academic vs industry perspectives in 3D bioprinting	6
A neuronal wiring platform through microridges for rationally engineered neural circuits	6
Investigation of the hepatic development in the coculture of hiPSCs-derived LSECs and HLCs in a fluidic microenvironment	6
Differential effects of vascular endothelial growth factor on glycocalyx of endothelial and tumor cells and potential targets for tumor metastasis	6
A human in vitro platform for the evaluation of pharmacology strategies in cardiac ischemia	6
Engineering CAR T cells for enhanced efficacy and safety	6
Progress in mimicking brain microenvironments to understand and treat neurological disorders	6