Birth Defects Research

Article	Citations
A 2019 global update on folic acid‐preventable spina bifida and anencephaly	39
Environmental mechanisms of orofacial clefts	30
Folate intake, markers of folate status and oral clefts: An updated set of systematic reviews and meta‐analyses	26
Role of epigenetics and miRNAs in orofacial clefts	24
Projected impact of mandatory food fortification with folic acid on neurosurgical capacity needed for treating spina bifida in Ethiopia	22
Transgenerational adverse effects of valproate? A patient report from 90 affected families	20
A multi‐country study of prevalence and early childhood mortality among children with omphalocele	19
Disparities in insurance coverage among hospitalized adult congenital heart disease patients before and after the Affordable Care Act	18
A global update on the status of prevention of folic acid‐preventable spina bifida and anencephaly in year 2020: 30‐Year anniversary of gaining knowledge about folic acid's prevention potential for ne	17
Identifying environmental risk factors and gene–environment interactions in holoprosencephaly	16
Pregnancy and infant outcomes by trimester of SARS‐CoV‐2 infection in pregnancy–SET‐NET, 22 jurisdictions, January 25, 2020–December 31, 2020	16
Academic achievement and needs of school‐aged children born with selected congenital anomalies: A systematic review and meta‐analysis	16
European trends in mortality in children with congenital anomalies: 2000–2015	16
Prenatal exposure to atrazine induces cryptorchidism and hypospadias in F1 male mouse offspring	15
First trimester COVID‐19 and the risk of major congenital malformations–International Registry of Coronavirus Exposure in Pregnancy	15
Examination of cortically projecting cholinergic neurons following exercise and environmental intervention in a rodent model of fetal alcohol spectrum disorders	15
A life‐table analysis of the intrauterine fate of malformed human embryos and fetuses	14
Prevalence of structural birth defects among infants with Down syndrome, 2013–2017: A US population‐based study	14
Bisphenol A decreases progesterone synthesis in human ovarian granulosa cells	14
Risk management of teratogenic medicines: A systematic review	13
Prevalence of critical congenital heart defects and selected co‐occurring congenital anomalies, 2014–2018: A U.S. population‐based study	13
Exposures influencing the developing central autonomic nervous system	13
Prenatal developmental toxicity of alkyl dimethyl benzyl ammonium chloride and didecyl dimethyl ammonium chloride in CD rats and New Zealand White rabbits	12
Developmental safety of nirmatrelvir in zebrafish (Danio rerio) embryos	12
Maternal ethnicity and the prevalence of British pregnancies affected by neural tube defects	12

A novel human stem cell‐based biomarker assay for in vitro assessment of developmental toxicity	12
Perfluorooctanoic acid inhibits the maturation rate of mouse oocytes cultured in vitro by triggering mitochondrial and DNA damage	12
Maternal age and the prevalence of congenital heart defects in Europe, 1995–2015: A register‐based study	12
Maternal biomarkers for early prediction of the neural tube defects pregnancies	11
Cardiopulmonary exercise testing during pregnancy	11
Prevalence and mortality among children with anorectal malformation: A multi‐country analysis	11
Resveratrol ameliorates toxic effects of cadmium on placental development in mouse placenta and human trophoblast cells	11
Developmental toxicity induced by triclosan exposure in zebrafish embryos	11
Risk factors and time trends for isolated craniosynostosis	10
Prevalence of congenital heart defects in Europe, 2008–2015: A registry‐based study	10
Zika virus‐induced brain malformations in chicken embryos	10
Yolk sac development, function and role in rodent pregnancy	9
Belimumab use during pregnancy: Interim results of the belimumab pregnancy registry	9
Moderate intensity aerobic exercise during pregnancy and 1‐month infant Morphometry	9
Maternal‐fetal outcomes of exercise applied in rats with mild hyperglycemia after embryonic implantation	9
Modification of the association between diabetes and birth defects by obesity, National Birth Defects Prevention Study, 1997–2011	9
Survival of infants born with esophageal atresia among 24 international birth defects surveillance programs	9
Fetal exposure to tofacitinib during the first trimester: A healthy newborn case report	9
Behavioral and neuroinflammatory changes caused by glyphosate: Base herbicide in mice offspring	8
Cigarette smoke induced neural tube defects by down‐regulating noggin expression	8
Gastroschisis in Ontario, Canada: 2012–2018	8
In‐utero cannabis exposure and long‐term psychiatric and neurodevelopmental outcomes: The limitations of existing literature and recommendations for future research	8
Gene–environment interactions between air pollution and biotransformation enzymes and risk of birth defects	8
Inpatient admissions and costs for adolescents and young adults with congenital heart defects in New York, 2009–2013	8
Prevalence of neural tube defects, maternal HIV status, and antiretroviral therapy from a hospital‐based birth defect surveillance in Kampala, Uganda	8
Maternotoxicity and fetotoxicity in Rattus norvegicus albinus exposed to tramadol during the late phase of pregnancy	8
Toward better assessments of developmental toxicity using stem cell‐based in vitro embryogenesis models	8
Maternal exposure to hydroxychloroquine and birth defects	8
Review of the state of science and evaluation of currently available in silico prediction models for reproductive and developmental toxicity: A case study on pesticides	8
Melatonin inhibits embryonic rat H9c2 cells growth through induction of apoptosis and cell cycle arrest via PI3K‐AKT signaling pathway	8
Clinical and neurodevelopmental outcomes based on brain imaging studies in a Colombian cohort of children with probable antenatal Zika virus exposure	7
Conjoined twins and conjoined triplets: At the heart of the matter	7
Comparison of DNA methylation patterns across tissue types in infants with tetralogy of Fallot	7
Quantitative in vitro to in vivo extrapolation for developmental toxicity potency of valproic acid analogues	7
Paternal exposure to di‐n‐butyl‐phthalate induced developmental toxicity in zebrafish (Danio rerio)	7
Relationship between achieving Sustainable Development Goals and promoting optimal care and prevention of birth defects globally	7
Readability, understandability, and quality of retinopathy of prematurity information on the web	7
Proportion of critical congenital heart defects attributable to unhealthy prepregnancy body mass index among women with live births in Florida, 2005–2016	7
Zika virus as a cause of birth defects: Were the teratogenic effects of Zika virus missed for decades?	7
Global birth defects app: An innovative tool for describing and coding congenital anomalies at birth in low resource settings	7
Post‐traumatic stress disorder, anxiety, and depression among adults with congenital heart defects	7
The accuracy of hospital discharge data in recording major congenital anomalies in Australia	7
No developmental toxicity observed with dolutegravir in rat whole embryo culture	7
Malarial PI4K inhibitor induced diaphragmatic hernias in rat: Potential link with mammalian kinase inhibition	7
Evaluating the proportion of isolated cases among a spectrum of birth defects in a population‐based registry	7
Teratogen update: Malaria in pregnancy and the use of antimalarial drugs in the first trimester	7
Cardiovascular function during early development is suppressed by cinnamon flavored, nicotine‐free, electronic cigarette vapor	6
Prenatal epigenetic factors are predisposing for neurodevelopmental disorders—Considering placenta as a model	6
Regulation of Oct4 in stem cells and neural crest cells	6
Myelomeningocele genotype–phenotype correlation findings in cilia, HH, PCP, and WNT signaling pathways	6

Re‐sequencing of candidate genes FOXF1, HSPA6, HAAO, and KYNU in 522 individuals with VATER/VACTERL, VACTER/VACTERL	6
Maternal cigarette smoking and alcohol consumption and congenital diaphragmatic hernia	6
Concomitant genetic defects potentiate the adverse impact of prenatal alcohol exposure on cardiac outflow tract maturation	6
Structural changes, increased hypoxia, and oxidative DNA damage in placenta due to maternal smokeless tobacco use	6
Prevalence of vascular disruption anomalies and association with young maternal age: A EUROCAT study to compare the United Kingdom with other European countries	6
Reproductive toxicity assessment of alkyl dimethyl benzyl ammonium chloride and didecyl dimethyl ammonium chloride in CD® rats	6
Limited surface examination to evaluate potential teratogens in a resource‐limited setting	6
Exposure to alirocumab during the first trimester of pregnancy: A case report	6
The effects of in ovo administered bisphenol A on tibial growth plate histology in chicken	6
Gamma aminobutyric acid signaling disturbances and altered astrocytic morphology associated with Bisphenol A induced cognitive impairments in rat offspring	6
Does it matter when I quit? Could I just cut down some? Links between trimester‐specific smoking amount, preterm birth, and low birth weight	6
In vitro effects of citral on the human myometrium: Potential adjunct therapy to prevent preterm births	6
Application of zebrafish in the study of craniomaxillofacial developmental anomalies	6
Prevalence of birth defects among infants with neonatal abstinence syndrome in Illinois, 2015–2016	5
Early‐lifeexposure to alcohol and the risk ofalcohol‐inducedliver disease in adulthood	5
The effect of different concentrations of cerium oxide during pregnancy on ovarian follicle development in neonatal mice	5
A putative adverse outcome network for neonatal mortality and lower birth weight in rodents: Applicability to per‐ and polyfluoroalkyl substances and relevance to human health	5
Parietal bone agenesis and athelia in retinoic acid embryopathy: An expansion of the phenotype	5
Patterns of multiple congenital anomalies in the National Birth Defect Prevention Study: Challenges and insights	5
Biallelic THOC6 pathogenic variants: Prenatal phenotype and review of the literature	5
Combined effects of maternal exposure to fungicides on behavioral development in F1‐generation mice: 2. Fixed‐dose study of thiabendazole	5
Systematic assessment of quaternary ammonium compounds for the potential to elicit developmental and reproductive effects	5
Describing characteristics of adults with and without congenital heart defects hospitalized with COVID‐19	5
Single‐cell profiling for advancing birth defects research and prevention	5
Folic acid antagonist use before and during pregnancy and risk for selected birth defects	5
Prenatal alcohol exposure can be determined from baby teeth: Proof of concept	5
Terminal transverse limb defects with “nubbins”	5
Leveraging a phenome‐wide approach to identify novel exposure‐birth defect associations: A proof of concept using maternal smoking and a spectrum of birth defects	5
Using high throughput screens to predict miscarriages with placental stem cells and long‐term stress effects with embryonic stem cells	5
Pregnancy in systemic lupus erythematosus	5
Perinatal nicotine exposure alters lung development and induces HMGB1‐RAGE expression in neonatal mice	5
Assessing the relationship between neonatal abstinence syndrome and birth defects in Delaware	5
Investigation of developmental toxicity of favipiravir on fetal bone and embryonic development	5
National population‐based estimates for major birth defects, 2016–2020	5
Maternal diabetes as a teratogenic factor for congenital heart defects in infants of diabetic mothers	5
Viewing teratogens through the lens of nicotinamide adenine dinucleotide (NAD+)	5
Final results from the ribavirin pregnancy registry, 2004–2020	5
Association of paternal smoking with the risk of neural tube defects in offspring: A systematic review and meta‐analysis of observational studies	4
Agreement between maternal report and medical records on use of medications during early pregnancy in New York	4
COG6‐CDG: Novel variants and novel malformation	4
Health‐related quality of life after 50 years in individuals with thalidomide embryopathy: Evidence from a German cross‐sectional survey	4
A cross‐sectional study of brownfields and birth defects	4
Dose range finding approach for rodent preweaning juvenile animal studies	4
A multi‐program analysis of cleft lip with cleft palate prevalence and mortality using data from 22 International Clearinghouse for Birth Defects Surveillance and Research programs, 1974–2014	4
School age educational outcomes of infants born with congenital diaphragmatic hernia	4
Prenatal diagnosis of Proteus syndrome: Diagnosis of an AKT1 mutation from amniocytes	4
Separation in genetic pathogenesis of mutations in FBN1‐TB5 region between autosomal dominant acromelic dysplasia and Marfan syndrome	4
Co‐occurrence of congenital anomalies by maternal race/ethnicity among infants and fetuses with Down syndrome, 2013–2017: A U.S. population‐based analysis	4
Periconceptional folic acid use prevents both rare and common neural tube defects in China	4
Translational potential of hiPSCs in predictive modeling of heart development and disease	4
Effect of buscopan, a compound that alleviates cramps, on the developing nervous system of the chick embryo	4
Causes of neonatal and postneonatal death among infants with birth defects in Texas	4
Identifying the landscape of developmental toxicity new approach methodologies	4
Role of coxsackie‐adenovirus receptor in cardiac development and pathogenesis of congenital heart disease	4
Characteristics and first‐year mortality, by lesion level, among infants with spina bifida in the New York State Birth Defects Registry, 2008–2017	4
Multiple subtypes of coxsackievirus group B can cause congenital heart disease	4
A spatial analysis of birth defects in Texas, 1999–2011	4
Distance from home to birth hospital, transfer, and mortality in neonates with hypoplastic left heart syndrome in California	4
Development and evaluation of standardized pregnancy identification and trimester distribution algorithms in U.S. IBM MarketScan® Commercial and Medicaid data	4
Comparison of germ cell differentiation of rat testis fragments cultured in knockout serum replacement versus Albumax™ I	4
Unfavorable postnatal outcome with significant dilation of the fetal main pulmonary artery near term	4
Maternal micronutrient deficiency and congenital heart disease risk: A systematic review of observational studies	4
Effect of chlorpyrifos and its metabolites on skeletal system development of chick embryo	4
Teratogenesis and the epigenetic programming of congenital defects: Why paternal exposures matter	4
The pro‐apoptotic Bax gene modifies susceptibility to craniofacial dysmorphology following gastrulation‐stage alcohol exposure	3
Physician hesitancy to recommend COVID‐19 vaccination in pregnancy as a cause of maternal deaths ‐ Robert Brent was prescient	3
The risk of major structural birth defects associated with seasonal influenza vaccination during pregnancy: A population‐based cohort study	3
Folic acid rescues all‐trans retinoic acid‐induced anorectal malformations in rats	3
Alobar holoprosencephaly in mining‐related areas of the Eastern region of the Democratic Republic of the Congo: A case series	3
Prenatal immobility stress: Relationship with oxidative stress, inflammation, apoptosis, and intrauterine growth restriction in rats	3
The association of nausea and vomiting of pregnancy, its treatments, and select birth defects: Findings from the National Birth Defect Prevention Study	3
Abnormal growth and morphogenesis of placenta at term is linked to adverse fetal development after perigestational alcohol consumption up to early gestation in mouse	3
Congenital cytomegalovirus surveillance in the United States	3
Risk of birth defects by pregestational type 1 or type 2 diabetes: National Birth Defects Prevention Study, 1997–2011	3
Reproductive and neurobehavioral effects of maternal exposure to dinotefuran in the F1‐generation mice	3
Physical activity and gestational weight gain predict physiological and perceptual responses to exercise during pregnancy	3
Amelioration of silymarin against cadmium‐induced toxicity in pregnant rats and their fetuses	3
Probing single ventricle heart defects with patient‐derived induced pluripotent stem cells and emerging technologies	3
Introduction to “Stem Cells” special issue	3
Evidence for a cluster of rare birth defects in the Ain department (France)	3

Pregnancy outcome after first trimester exposure to vortioxetine: A case series	3
Cannabis during pregnancy: A way to transfer an impairment to later life	3
Gestational exposure to triphenyl phosphate induces epigenetic modifications in C57Bl/6 fetal liver	3
Biological impacts of the green synthesized silver nanoparticles on the pregnant albino rats and their fetuses	3
Pandemic stressors and vaccine hesitancy among young, pregnant Black people: A qualitative study of health disparities during a global pandemic	3
Prepregnancy body mass index and spina bifida: Potential contributions of bias	3
Ascertainment of malformations in pregnancy registries: Lessons learned in the North American AED Pregnancy Registry	3
Abnormal placental cord insertion, hypertensive disorders of pregnancy and birth length may be involved in development of hypospadias in male fetuses	3
Tris(4‐chlorophenyl)methane and tris(4‐chlorophenyl)methanol disrupt pancreatic organogenesis and gene expression in zebrafish embryos	3
Developmental toxicity of remdesivir, an anti‐COVID‐19 drug, is implicated by in vitro assays using morphogenetic embryoid bodies of mouse and human pluripotent stem cells	3
Association between maternal body mass index and congenital anomalies: A case‐control study in Tuscany (Italy)	3
Medicaid healthcare expenditures for infants with birth defects potentially related to Zika virus infection in North Carolina, 2011–2016	3
Comparison of inherited neural tube defects in companion animals and livestock	3
Neural tube defects prevalence does not increase after modification of the folic acid fortification program in Chile	3
The possible effect of lactoferrin on the epigenetic characteristics of early mammalian embryos exposed to bisphenol A	3
Lesion‐specific mortality due to congenital heart disease in U.S. adults from 1999 to 2017	3
The miR‐17‐92 cluster in cardiac health and disease	3
Preclinical development of a novel Group B Streptococcus (GBS) vaccine candidate for maternal immunization based upon the alpha‐like protein family of GBS surfa	3
Periconceptional nonsteroidal anti‐inflammatory drug use, folic acid intake, and the risk of spina bifida	3
Maternal dietary caffeine consumption and risk of birth defects in the National Birth Defects Prevention Study, 1997–2011	3
Dolutegravir and rat whole embryo culture	3