Birth Defects Research

Article	Citations
Plastics derived endocrine‐disrupting compounds and their effects on early development	82
Bisphenols and phthalates: Plastic chemical exposures can contribute to adverse cardiovascular health outcomes	50
Chemical components of plastics as endocrine disruptors: Overview and commentary	42
Cellular and developmental basis of orofacial clefts	39
How microplastic components influence the immune system and impact on children health: Focus on cancer	39
Genetics and signaling mechanisms of orofacial clefts	38
A 2019 global update on folic acid‐preventable spina bifida and anencephaly	38
The detrimental effect of microplastics on critical periods of development in the neuroendocrine system	30
Update on the gestational effects of maternal hyperthermia	28
Environmental mechanisms of orofacial clefts	26
Folate intake, markers of folate status and oral clefts: An updated set of systematic reviews and meta‐analyses	24
Teratogen update: Zika virus and pregnancy	21
Role of epigenetics and miRNAs in orofacial clefts	21
Risk of malformation after ondansetron in pregnancy: An updated systematic review and meta‐analysis	21
Maternal risk factors for gastroschisis: A population‐based case–control study	17
Disparities in insurance coverage among hospitalized adult congenital heart disease patients before and after the Affordable Care Act	17
Projected impact of mandatory food fortification with folic acid on neurosurgical capacity needed for treating spina bifida in Ethiopia	17
Impact of Bisphenol A on neural tube development in 48‐hr chicken embryos	17
Academic achievement and needs of school‐aged children born with selected congenital anomalies: A systematic review and meta‐analysis	16
Update on the developmental consequences of cannabis use during pregnancy and lactation	16
Prenatal alcohol exposure induced congenital heart diseases: From bench to bedside	16
Atypical cardiac defects in patients with RASopathies: Updated data on CARNET study	16
Transgenerational adverse effects of valproate? A patient report from 90 affected families	16
An exercise program throughout pregnancy: Barakat model	15
European trends in mortality in children with congenital anomalies: 2000–2015	15

Identifying environmental risk factors and gene–environment interactions in holoprosencephaly	14
A multi‐country study of prevalence and early childhood mortality among children with omphalocele	14
Examination of cortically projecting cholinergic neurons following exercise and environmental intervention in a rodent model of fetal alcohol spectrum disorders	14
A life‐table analysis of the intrauterine fate of malformed human embryos and fetuses	14
Prenatal exposure to atrazine induces cryptorchidism and hypospadias in F1 male mouse offspring	13
Use of antihistamine medications during early pregnancy and selected birth defects: The National Birth Defects Prevention Study, 1997–2011	13
Pregnancy and infant outcomes by trimester of SARS‐CoV‐2 infection in pregnancy–SET‐NET, 22 jurisdictions, January 25, 2020–December 31, 2020	13
Maternal risk factors for the VACTERL association: A EUROCAT case–control study	13
Bisphenol A decreases progesterone synthesis in human ovarian granulosa cells	12
First trimester COVID‐19 and the risk of major congenital malformations–International Registry of Coronavirus Exposure in Pregnancy	12
A global update on the status of prevention of folic acid‐preventable spina bifida and anencephaly in year 2020: 30‐Year anniversary of gaining knowledge about folic acid's prevention potential for ne	12
Prevalence of structural birth defects among infants with Down syndrome, 2013–2017: A US population‐based study	12
Associations between cumulative environmental quality and ten selected birth defects in Texas	11
Maternal, pregnancy, and neonatal outcomes for women with Turner syndrome	11
The association between legalization of recreational marijuana use and birth outcomes in Colorado and Washington state	11
Risk management of teratogenic medicines: A systematic review	10
Resveratrol ameliorates toxic effects of cadmium on placental development in mouse placenta and human trophoblast cells	10
Prevalence of critical congenital heart defects and selected co‐occurring congenital anomalies, 2014–2018: A U.S. population‐based study	10
A novel human stem cell‐based biomarker assay for in vitro assessment of developmental toxicity	10
Exposures influencing the developing central autonomic nervous system	10
Preconception telomere length as a novel maternal biomarker to assess the risk of spina bifida in the offspring	10
Developmental toxicity induced by triclosan exposure in zebrafish embryos	9
Prenatal developmental toxicity of alkyl dimethyl benzyl ammonium chloride and didecyl dimethyl ammonium chloride in CD rats and New Zealand White rabbits	9
Swimming toward solutions: Using fish and frogs as models for understanding RASopathies	9
Modification of the association between diabetes and birth defects by obesity, National Birth Defects Prevention Study, 1997–2011	9
Zika virus‐induced brain malformations in chicken embryos	9
Perfluorooctanoic acid inhibits the maturation rate of mouse oocytes cultured in vitro by triggering mitochondrial and DNA damage	9
Maternal ethnicity and the prevalence of British pregnancies affected by neural tube defects	9
Periconceptional folic acid supplement use among women of reproductive age and its determinants in central rural Germany: Results from a cross sectional study	8
Cardiopulmonary exercise testing during pregnancy	8
Moderate intensity aerobic exercise during pregnancy and 1‐month infant Morphometry	8
Inpatient admissions and costs for adolescents and young adults with congenital heart defects in New York, 2009–2013	8
Survival of infants born with esophageal atresia among 24 international birth defects surveillance programs	8
Maternal biomarkers for early prediction of the neural tube defects pregnancies	8
Cigarette smoke induced neural tube defects by down‐regulating noggin expression	8
Maternotoxicity and fetotoxicity in Rattus norvegicus albinus exposed to tramadol during the late phase of pregnancy	8
Congenital diaphragmatic hernia and maternal dietary nutrient pathways and diet quality	7
Behavioral and neuroinflammatory changes caused by glyphosate: Base herbicide in mice offspring	7
Maternal‐fetal outcomes of exercise applied in rats with mild hyperglycemia after embryonic implantation	7
Fetal exposure to tofacitinib during the first trimester: A healthy newborn case report	7
Prevalence of congenital heart defects in Europe, 2008–2015: A registry‐based study	7
Teratogen update: Malaria in pregnancy and the use of antimalarial drugs in the first trimester	7
Gastroschisis in Ontario, Canada: 2012–2018	7
Gene–environment interactions between air pollution and biotransformation enzymes and risk of birth defects	7
No developmental toxicity observed with dolutegravir in rat whole embryo culture	7
Modeling shows high potential of folic acid‐fortified salt to accelerate global prevention of major neural tube defects	7
Risk factors and time trends for isolated craniosynostosis	7
Relationship between achieving Sustainable Development Goals and promoting optimal care and prevention of birth defects globally	7
Teratogen update: Topical use and third‐generation retinoids	7
Prevalence and mortality among children with anorectal malformation: A multi‐country analysis	7

Paternal exposure to recreational drugs before conception and its effect on live‐born offspring: A scoping review	7
Maternal age and the prevalence of congenital heart defects in Europe, 1995–2015: A register‐based study	7
Developmental safety of nirmatrelvir in zebrafish (Danio rerio) embryos	7
Toward better assessments of developmental toxicity using stem cell‐based in vitro embryogenesis models	6
Variations in maternal vitamin A intake modifies phenotypes in a mouse model of 22q11.2 deletion syndrome	6
The accuracy of hospital discharge data in recording major congenital anomalies in Australia	6
Does it matter when I quit? Could I just cut down some? Links between trimester‐specific smoking amount, preterm birth, and low birth weight	6
Belimumab use during pregnancy: Interim results of the belimumab pregnancy registry	6
Post‐traumatic stress disorder, anxiety, and depression among adults with congenital heart defects	6
Clinical and neurodevelopmental outcomes based on brain imaging studies in a Colombian cohort of children with probable antenatal Zika virus exposure	6
Perspectives on challenges and opportunities for birth defects surveillance programs during and after the COVID‐19 era	6
Sinus pericranii, skull defects, and structural brain anomalies in TRAF7‐related disorder	6
Zika virus as a cause of birth defects: Were the teratogenic effects of Zika virus missed for decades?	6
Prevalence of vascular disruption anomalies and association with young maternal age: A EUROCAT study to compare the United Kingdom with other European countries	6
Re‐sequencing of candidate genes FOXF1, HSPA6, HAAO, and KYNU in 522 individuals with VATER/VACTERL, VACTER/VACTERL	6
Melatonin inhibits embryonic rat H9c2 cells growth through induction of apoptosis and cell cycle arrest via PI3K‐AKT signaling pathway	6
Readability, understandability, and quality of retinopathy of prematurity information on the web	6
Conjoined twins and conjoined triplets: At the heart of the matter	6
Regulation of Oct4 in stem cells and neural crest cells	6
Global birth defects app: An innovative tool for describing and coding congenital anomalies at birth in low resource settings	6
Folic acid prescribed to prenatal and postpartum women who are also prescribed antiepileptic drugs in Japan: Data from a health administrative database	6
Parietal bone agenesis and athelia in retinoic acid embryopathy: An expansion of the phenotype	5
Biallelic THOC6 pathogenic variants: Prenatal phenotype and review of the literature	5
Early‐lifeexposure to alcohol and the risk ofalcohol‐inducedliver disease in adulthood	5
Perinatal nicotine exposure alters lung development and induces HMGB1‐RAGE expression in neonatal mice	5
Prevalence of neural tube defects, maternal HIV status, and antiretroviral therapy from a hospital‐based birth defect surveillance in Kampala, Uganda	5
Analysis of proportional data in reproductive and developmental toxicity studies: Comparison of sensitivities of logit transformation, arcsine square root transformation, and nonparametric analysis	5
Review of the state of science and evaluation of currently available in silico prediction models for reproductive and developmental toxicity: A case study on pesticides	5
Limited surface examination to evaluate potential teratogens in a resource‐limited setting	5
Concomitant genetic defects potentiate the adverse impact of prenatal alcohol exposure on cardiac outflow tract maturation	5
Developmental 2,3,7,8‐tetrachlorodibenzo‐p‐dioxin exposure of either parent enhances the risk of necrotizing enterocolitis in neonatal mice	5
Reproductive toxicity assessment of alkyl dimethyl benzyl ammonium chloride and didecyl dimethyl ammonium chloride in CD® rats	5
Malarial PI4K inhibitor induced diaphragmatic hernias in rat: Potential link with mammalian kinase inhibition	5
Evaluating the proportion of isolated cases among a spectrum of birth defects in a population‐based registry	5
A novel biallelic splice‐site variant in the LRP4 gene causes sclerosteosis 2	5
Noonan syndrome on the African Continent	5
Cardiovascular function during early development is suppressed by cinnamon flavored, nicotine‐free, electronic cigarette vapor	5
Comparison of DNA methylation patterns across tissue types in infants with tetralogy of Fallot	5
Structural changes, increased hypoxia, and oxidative DNA damage in placenta due to maternal smokeless tobacco use	5
A model partnership for communication and dissemination of scientific recommendations for pregnant women during the emergency response to the Zika virus outbreak: MotherToBaby and the Cente	5
Vasoactive exposures and risk of amniotic band syndrome and terminal transverse limb deficiencies	5
Paternal exposure to di‐n‐butyl‐phthalate induced developmental toxicity in zebrafish (Danio rerio)	5
Methoxyacetic acid inhibits histone deacetylase and impairs axial elongation morphogenesis of mouse gastruloids in a retinoic acid signaling‐dependent manner	4
School age educational outcomes of infants born with congenital diaphragmatic hernia	4
Teratogen update: Amphetamines	4
Maternal cigarette smoking and alcohol consumption and congenital diaphragmatic hernia	4
Multiple subtypes of coxsackievirus group B can cause congenital heart disease	4
Leveraging a phenome‐wide approach to identify novel exposure‐birth defect associations: A proof of concept using maternal smoking and a spectrum of birth defects	4
Exposure to alirocumab during the first trimester of pregnancy: A case report	4
The effects of in ovo administered bisphenol A on tibial growth plate histology in chicken	4
Gamma aminobutyric acid signaling disturbances and altered astrocytic morphology associated with Bisphenol A induced cognitive impairments in rat offspring	4
Health‐related quality of life after 50 years in individuals with thalidomide embryopathy: Evidence from a German cross‐sectional survey	4
Teratogen?	4
Investigation of developmental toxicity of favipiravir on fetal bone and embryonic development	4
In vitro effects of citral on the human myometrium: Potential adjunct therapy to prevent preterm births	4
Application of zebrafish in the study of craniomaxillofacial developmental anomalies	4
Maternal diabetes as a teratogenic factor for congenital heart defects in infants of diabetic mothers	4
Teratogen update: Antithyroid medications	4
Association of paternal smoking with the risk of neural tube defects in offspring: A systematic review and meta‐analysis of observational studies	4
Role of coxsackie‐adenovirus receptor in cardiac development and pathogenesis of congenital heart disease	4
Combined effects of maternal exposure to fungicides on behavioral development in F1‐generation mice: 2. Fixed‐dose study of thiabendazole	4
Prenatal diagnosis of Proteus syndrome: Diagnosis of an AKT1 mutation from amniocytes	4
Prevalence of birth defects among infants with neonatal abstinence syndrome in Illinois, 2015–2016	4
Effect of buscopan, a compound that alleviates cramps, on the developing nervous system of the chick embryo	4
The risk of major structural birth defects associated with seasonal influenza vaccination during pregnancy: A population‐based cohort study	4
Assessing the relationship between neonatal abstinence syndrome and birth defects in Delaware	4
Myelomeningocele genotype–phenotype correlation findings in cilia, HH, PCP, and WNT signaling pathways	4
Maternal risk associated with the VACTERL association: A case–control study	4
Folic acid antagonist use before and during pregnancy and risk for selected birth defects	4
Patterns of multiple congenital anomalies in the National Birth Defect Prevention Study: Challenges and insights	4
Terminal transverse limb defects with “nubbins”	4
Final results from the ribavirin pregnancy registry, 2004–2020	4
Pregnancy in systemic lupus erythematosus	4
In‐utero cannabis exposure and long‐term psychiatric and neurodevelopmental outcomes: The limitations of existing literature and recommendations for future research	4
Prenatal epigenetic factors are predisposing for neurodevelopmental disorders—Considering placenta as a model	4
The effect of different concentrations of cerium oxide during pregnancy on ovarian follicle development in neonatal mice	4
Development and evaluation of standardized pregnancy identification and trimester distribution algorithms in U.S. IBM MarketScan® Commercial and Medicaid data	4
Comparison of germ cell differentiation of rat testis fragments cultured in knockout serum replacement versus Albumax™ I	4
Maternal exposure to hydroxychloroquine and birth defects	4
Single‐cell profiling for advancing birth defects research and prevention	4

COG6‐CDG: Novel variants and novel malformation	3
3‐Methylglutaconic aciduria type VIII in an Indian neonate	3
Describing characteristics of adults with and without congenital heart defects hospitalized with COVID‐19	3
Teratogenesis and the epigenetic programming of congenital defects: Why paternal exposures matter	3
Abnormal placental cord insertion, hypertensive disorders of pregnancy and birth length may be involved in development of hypospadias in male fetuses	3
Separation in genetic pathogenesis of mutations in FBN1‐TB5 region between autosomal dominant acromelic dysplasia and Marfan syndrome	3
The pro‐apoptotic Bax gene modifies susceptibility to craniofacial dysmorphology following gastrulation‐stage alcohol exposure	3
Exploratory analysis of machine learning approaches for surveillance of Zika‐associated birth defects	3
Physical activity and gestational weight gain predict physiological and perceptual responses to exercise during pregnancy	3
Neural tube defects prevalence does not increase after modification of the folic acid fortification program in Chile	3
Maternal exposure to methylmercury causes an impairment in ependymal cilia motility in the third ventricle and dilation of lateral ventricles in mice offspring	3
The possible effect of lactoferrin on the epigenetic characteristics of early mammalian embryos exposed to bisphenol A	3
Developmental toxicity of remdesivir, an anti‐COVID‐19 drug, is implicated by in vitro assays using morphogenetic embryoid bodies of mouse and human pluripotent stem cells	3
A cross‐sectional study of brownfields and birth defects	3
Yolk sac development, function and role in rodent pregnancy	3
Distance from home to birth hospital, transfer, and mortality in neonates with hypoplastic left heart syndrome in California	3
Identifying the landscape of developmental toxicity new approach methodologies	3
Comparison of inherited neural tube defects in companion animals and livestock	3
Reproductive and neurobehavioral effects of maternal exposure to dinotefuran in the F1‐generation mice	3
Dolutegravir and rat whole embryo culture	3
Viewing teratogens through the lens of nicotinamide adenine dinucleotide (NAD+)	3
Prenatal immobility stress: Relationship with oxidative stress, inflammation, apoptosis, and intrauterine growth restriction in rats	3
Characterization of individuals with selected muscular dystrophies from the expanded pilot of the Muscular Dystrophy Surveillance, Tracking and Research Network (MD STARnet) in the United S	3
Hydrocephaly associated with compound heterozygous alterations in TRAPPC12	3
Periconceptional folic acid use prevents both rare and common neural tube defects in China	3
A putative adverse outcome network for neonatal mortality and lower birth weight in rodents: Applicability to per‐ and polyfluoroalkyl substances and relevance to human health	3
Maternal dietary caffeine consumption and risk of birth defects in the National Birth Defects Prevention Study, 1997–2011	3
Biological impacts of the green synthesized silver nanoparticles on the pregnant albino rats and their fetuses	3
Proportion of critical congenital heart defects attributable to unhealthy prepregnancy body mass index among women with live births in Florida, 2005–2016	3
Causes of neonatal and postneonatal death among infants with birth defects in Texas	3
Abnormal growth and morphogenesis of placenta at term is linked to adverse fetal development after perigestational alcohol consumption up to early gestation in mouse	3
Medicaid healthcare expenditures for infants with birth defects potentially related to Zika virus infection in North Carolina, 2011–2016	3
The effects of aerobic exercise on markers of maternal metabolism during pregnancy	3
Characteristics and first‐year mortality, by lesion level, among infants with spina bifida in the New York State Birth Defects Registry, 2008–2017	3
Using high throughput screens to predict miscarriages with placental stem cells and long‐term stress effects with embryonic stem cells	3
Compound craniosynostosis, intellectual disability, and Noonan‐like facial dysmorphism associated with 7q32.3‐q35 deletion	3
Pregnancy outcome after first trimester exposure to vortioxetine: A case series	3
A spatial analysis of birth defects in Texas, 1999–2011	3
Quantitative in vitro to in vivo extrapolation for developmental toxicity potency of valproic acid analogues	3
Systematic assessment of quaternary ammonium compounds for the potential to elicit developmental and reproductive effects	3
Dose range finding approach for rodent preweaning juvenile animal studies	3
Agreement between maternal report and medical records on use of medications during early pregnancy in New York	3
Introduction to “Stem Cells” special issue	3
Lesion‐specific mortality due to congenital heart disease in U.S. adults from 1999 to 2017	3