Birth Defects Research

Article	Citations
National population‐based estimates for major birth defects, 2010–2014	384
Plastics derived endocrine‐disrupting compounds and their effects on early development	63
Population‐based birth defects data in the United States, 2012–2016: A focus on abdominal wall defects	41
Effects of low‐dose chlorpyrifos on neurobehavior and potential mechanisms: A review of studies in rodents, zebrafish, and Caenorhabditis elegans	39
Cellular and developmental basis of orofacial clefts	38
Genetics and signaling mechanisms of orofacial clefts	36
Bisphenols and phthalates: Plastic chemical exposures can contribute to adverse cardiovascular health outcomes	36
A 2019 global update on folic acid‐preventable spina bifida and anencephaly	35
Chemical components of plastics as endocrine disruptors: Overview and commentary	29
Mandatory newborn screening in the United States: History, current status, and existential challenges	27
Genome‐wide association studies of structural birth defects: A review and commentary	25
How microplastic components influence the immune system and impact on children health: Focus on cancer	25
Update on the gestational effects of maternal hyperthermia	24
Environmental mechanisms of orofacial clefts	23
The detrimental effect of microplastics on critical periods of development in the neuroendocrine system	22
Folate intake, markers of folate status and oral clefts: An updated set of systematic reviews and meta‐analyses	19
Role of epigenetics and miRNAs in orofacial clefts	19
The impact of perinatal nicotine exposure on fetal lung development and subsequent respiratory morbidity	18
PBX‐WNT‐P63‐IRF6 pathway in nonsyndromic cleft lip and palate	16
Risk of malformation after ondansetron in pregnancy: An updated systematic review and meta‐analysis	16
Teratogen update: Zika virus and pregnancy	16
Atypical cardiac defects in patients with RASopathies: Updated data on CARNET study	16
The role of teratogens in neural crest development	15
Disparities in insurance coverage among hospitalized adult congenital heart disease patients before and after the Affordable Care Act	15
Comorbidities in situs inversus totalis: A hospital‐based study	15

Projected impact of mandatory food fortification with folic acid on neurosurgical capacity needed for treating spina bifida in Ethiopia	14
An exercise program throughout pregnancy: Barakat model	14
Current landscape of prenatal genetic screening and testing	14
Prenatal alcohol exposure induced congenital heart diseases: From bench to bedside	13
A multi‐country study of prevalence and early childhood mortality among children with omphalocele	12
Prenatal exposure to atrazine induces cryptorchidism and hypospadias in F1 male mouse offspring	12
Absence of developmental and reproductive toxicity in animals exposed to dolutegravir	12
Identifying environmental risk factors and gene–environment interactions in holoprosencephaly	12
European trends in mortality in children with congenital anomalies: 2000–2015	12
Impact of Bisphenol A on neural tube development in 48‐hr chicken embryos	12
Maternal risk factors for the VACTERL association: A EUROCAT case–control study	12
Update on the developmental consequences of cannabis use during pregnancy and lactation	12
Use of antihistamine medications during early pregnancy and selected birth defects: The National Birth Defects Prevention Study, 1997–2011	11
A life‐table analysis of the intrauterine fate of malformed human embryos and fetuses	11
Maternal risk factors for gastroschisis: A population‐based case–control study	11
Toxic effects of maternal exposure to silver nanoparticles on mice fetal development during pregnancy	11
Examination of cortically projecting cholinergic neurons following exercise and environmental intervention in a rodent model of fetal alcohol spectrum disorders	10
Animal models of gene–alcohol interactions	9
Refinement of inducible gene deletion in embryos of pregnant mice	9
Transgenerational adverse effects of valproate? A patient report from 90 affected families	9
Maternal, pregnancy, and neonatal outcomes for women with Turner syndrome	9
The association between legalization of recreational marijuana use and birth outcomes in Colorado and Washington state	9
Academic achievement and needs of school‐aged children born with selected congenital anomalies: A systematic review and meta‐analysis	8
Bisphenol A decreases progesterone synthesis in human ovarian granulosa cells	8
Is preparation a good reason for prenatal genetic testing? Ethical and critical questions	8
Prevalence of structural birth defects among infants with Down syndrome, 2013–2017: A US population‐based study	8
Swimming toward solutions: Using fish and frogs as models for understanding RASopathies	8
Maternal surgery and anesthesia during pregnancy and risk of birth defects in the National Birth Defects Prevention Study, 1997–2011	8
Preconception telomere length as a novel maternal biomarker to assess the risk of spina bifida in the offspring	8
Cytogenetic and molecular diagnostic testing associated with prenatal and postnatal birth defects	8
A global update on the status of prevention of folic acid‐preventable spina bifida and anencephaly in year 2020: 30‐Year anniversary of gaining knowledge about folic acid's prevention potential for ne	8
Association between maternal occupational exposure to polycyclic aromatic hydrocarbons and rare birth defects of the face and central nervous system	8
Prenatal developmental toxicity of alkyl dimethyl benzyl ammonium chloride and didecyl dimethyl ammonium chloride in CD rats and New Zealand White rabbits	8
No developmental toxicity observed with dolutegravir in rat whole embryo culture	7
Modeling shows high potential of folic acid‐fortified salt to accelerate global prevention of major neural tube defects	7
Cardiopulmonary exercise testing during pregnancy	7
Orthopedic findings in arthrogryposis and congenital Zika syndrome: A case series	7
Smith‐Lemli‐Opitz syndrome — Fetal phenotypes with special reference to the syndrome‐specific internal malformation pattern	7
Maternal‐fetal outcomes of exercise applied in rats with mild hyperglycemia after embryonic implantation	7
The effect of low alcohol consumption during pregnancy on the lipid peroxidation‐antioxidant defense system of women, their alcohol‐exposed infants, and growth, health, and developmental outcomes	7
Zika virus‐induced brain malformations in chicken embryos	7
Maternotoxicity and fetotoxicity in Rattus norvegicus albinus exposed to tramadol during the late phase of pregnancy	7
Exposures influencing the developing central autonomic nervous system	7
Diaphragmatic paralysis: Evaluation in infants with congenital Zika syndrome	7
Maternal ethnicity and the prevalence of British pregnancies affected by neural tube defects	7
A novel human stem cell‐based biomarker assay for in vitro assessment of developmental toxicity	7
Relationship between achieving Sustainable Development Goals and promoting optimal care and prevention of birth defects globally	7
Does in vitro fertilization affect the expression of miRNAs and their biogenesis pathway in preimplantation mouse embryos?	6
Survival of infants born with esophageal atresia among 24 international birth defects surveillance programs	6
Resveratrol ameliorates toxic effects of cadmium on placental development in mouse placenta and human trophoblast cells	6

Gene–environment interactions between air pollution and biotransformation enzymes and risk of birth defects	6
The accuracy of hospital discharge data in recording major congenital anomalies in Australia	6
Perfluorooctanoic acid inhibits the maturation rate of mouse oocytes cultured in vitro by triggering mitochondrial and DNA damage	6
Associations between cumulative environmental quality and ten selected birth defects in Texas	6
Comorbidities in children with intellectual disabilities	6
Tetanus, diphtheria, and pertussis vaccine (Tdap) in pregnancy and risk of major birth defects in the offspring	6
Maternal biomarkers for early prediction of the neural tube defects pregnancies	6
Inpatient admissions and costs for adolescents and young adults with congenital heart defects in New York, 2009–2013	6
Association between maternal pregestational diabetes mellitus and spina bifida: A population‐based case–control study, Finland, 2000–2014	6
Deletion of neural tube defect‐associated gene Mthfd1l causes reduced cranial mesenchyme density	6
Risk factors and time trends for isolated craniosynostosis	6
Teratogen update: Malaria in pregnancy and the use of antimalarial drugs in the first trimester	6
Periconceptional folic acid supplement use among women of reproductive age and its determinants in central rural Germany: Results from a cross sectional study	6
Perspectives on challenges and opportunities for birth defects surveillance programs during and after the COVID‐19 era	6
Concepts in the neurosurgical care of patients with spinal neural tube defects: An embryologic approach	6
Risk management of teratogenic medicines: A systematic review	6
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Limited surface examination to evaluate potential teratogens in a resource‐limited setting	5
Developmental safety of nirmatrelvir in zebrafish (Danio rerio) embryos	5
Paternal exposure to di‐n‐butyl‐phthalate induced developmental toxicity in zebrafish (Danio rerio)	5
Noonan syndrome on the African Continent	5
Perinatal nicotine exposure alters lung development and induces HMGB1‐RAGE expression in neonatal mice	5
Reproductive toxicity assessment of alkyl dimethyl benzyl ammonium chloride and didecyl dimethyl ammonium chloride in CD® rats	5
Modification of the association between diabetes and birth defects by obesity, National Birth Defects Prevention Study, 1997–2011	5
Developmental toxicity induced by triclosan exposure in zebrafish embryos	5
Congenital diaphragmatic hernia and maternal dietary nutrient pathways and diet quality	5
Moderate intensity aerobic exercise during pregnancy and 1‐month infant Morphometry	5
Teratogen update: Topical use and third‐generation retinoids	5
Structural changes, increased hypoxia, and oxidative DNA damage in placenta due to maternal smokeless tobacco use	5
First trimester COVID‐19 and the risk of major congenital malformations–International Registry of Coronavirus Exposure in Pregnancy	5
Post‐traumatic stress disorder, anxiety, and depression among adults with congenital heart defects	5
The teratogenic effects of sertraline in mice	5
Melatonin inhibits embryonic rat H9c2 cells growth through induction of apoptosis and cell cycle arrest via PI3K‐AKT signaling pathway	5
Developmental 2,3,7,8‐tetrachlorodibenzo‐p‐dioxin exposure of either parent enhances the risk of necrotizing enterocolitis in neonatal mice	5
A model partnership for communication and dissemination of scientific recommendations for pregnant women during the emergency response to the Zika virus outbreak: MotherToBaby and the Cente	5
Readability, understandability, and quality of retinopathy of prematurity information on the web	4
Association between body mass index and folate insufficiency indicative of neural tube defects risk among nonpregnant women of childbearing age in the United States, NHANES, 2007–2010	4
The effects of in ovo administered bisphenol A on tibial growth plate histology in chicken	4
Assessing the relationship between neonatal abstinence syndrome and birth defects in Delaware	4
Mortality by mode of delivery among infants with spina bifida in Texas	4
Malarial PI4K inhibitor induced diaphragmatic hernias in rat: Potential link with mammalian kinase inhibition	4
A novel biallelic splice‐site variant in the LRP4 gene causes sclerosteosis 2	4
GTP hydrolysis is modulated by Arg34 in the RASopathy‐associated KRASP34R	4
In‐utero cannabis exposure and long‐term psychiatric and neurodevelopmental outcomes: The limitations of existing literature and recommendations for future research	4
A pilot study on the effect of early provision of dietary docosahexaenoic acid on testis development, functions, and sperm quality in rats exposed to prenatal ethanol	4
Toward better assessments of developmental toxicity using stem cell‐based in vitro embryogenesis models	4
Association between maternal periconceptional alcohol consumption and neural tube defects: Findings from the National Birth Defects Prevention Study, 1997–2011	4
Variations in maternal vitamin A intake modifies phenotypes in a mouse model of 22q11.2 deletion syndrome	4
Maternal exposure to hydroxychloroquine and birth defects	4
Global birth defects app: An innovative tool for describing and coding congenital anomalies at birth in low resource settings	4
Folic acid prescribed to prenatal and postpartum women who are also prescribed antiepileptic drugs in Japan: Data from a health administrative database	4
Analysis of proportional data in reproductive and developmental toxicity studies: Comparison of sensitivities of logit transformation, arcsine square root transformation, and nonparametric analysis	4
Gastroschisis in Ontario, Canada: 2012–2018	4
Cardiovascular function during early development is suppressed by cinnamon flavored, nicotine‐free, electronic cigarette vapor	4
The de‐coders: A historical perspective of the genetic counseling profession	4
Prevalence of birth defects among infants with neonatal abstinence syndrome in Illinois, 2015–2016	4
Conjoined twins and conjoined triplets: At the heart of the matter	4
Comparison of germ cell differentiation of rat testis fragments cultured in knockout serum replacement versus Albumax™ I	4
Prevalence of neural tube defects, maternal HIV status, and antiretroviral therapy from a hospital‐based birth defect surveillance in Kampala, Uganda	4
Review of the state of science and evaluation of currently available in silico prediction models for reproductive and developmental toxicity: A case study on pesticides	4
Maternal risk associated with the VACTERL association: A case–control study	4
Exposure to alirocumab during the first trimester of pregnancy: A case report	4
Multiple dose treatment reduces cyclophosphamide‐induced ovarian follicular loss in mice	4
Regulation of Oct4 in stem cells and neural crest cells	3
Medicaid healthcare expenditures for infants with birth defects potentially related to Zika virus infection in North Carolina, 2011–2016	3
Hydrocephaly associated with compound heterozygous alterations in TRAPPC12	3
Of embryos and tumors: Cyclopia and the relevance of mechanistic teratology	3
Belimumab use during pregnancy: Interim results of the belimumab pregnancy registry	3
Compound craniosynostosis, intellectual disability, and Noonan‐like facial dysmorphism associated with 7q32.3‐q35 deletion	3
Single‐cell profiling for advancing birth defects research and prevention	3
Biallelic THOC6 pathogenic variants: Prenatal phenotype and review of the literature	3
Abnormal growth and morphogenesis of placenta at term is linked to adverse fetal development after perigestational alcohol consumption up to early gestation in mouse	3
Characterizing the effects of in utero exposure to valproic acid on murine fetal heart development	3
Pregnancy and infant outcomes by trimester of SARS‐CoV‐2 infection in pregnancy–SET‐NET, 22 jurisdictions, January 25, 2020–December 31, 2020	3
Early‐life exposure to alcohol and the risk of alcohol‐induced liver disease in adulthood	3
5‐year experience of a tertiary center in major congenital abnormalities in singleton pregnancies	3
Abnormal placental cord insertion, hypertensive disorders of pregnancy and birth length may be involved in development of hypospadias in male fetuses	3
Teratogen?	3
Role of coxsackie‐adenovirus receptor in cardiac development and pathogenesis of congenital heart disease	3
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Gamma aminobutyric acid signaling disturbances and altered astrocytic morphology associated with Bisphenol A induced cognitive impairments in rat offspring	3
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Prevalence of critical congenital heart defects and selected co‐occurring congenital anomalies, 2014–2018: A U.S. population‐based study	3
Vasoactive exposures and risk of amniotic band syndrome and terminal transverse limb deficiencies	3
Clinical and neurodevelopmental outcomes based on brain imaging studies in a Colombian cohort of children with probable antenatal Zika virus exposure	3
Myelomeningocele genotype–phenotype correlation findings in cilia, HH, PCP, and WNT signaling pathways	3
Pregnancy in systemic lupus erythematosus	3
Parietal bone agenesis and athelia in retinoic acid embryopathy: An expansion of the phenotype	3
Behavioral and neuroinflammatory changes caused by glyphosate: Base herbicide in mice offspring	3
Lesion‐specific mortality due to congenital heart disease in U.S. adults from 1999 to 2017	3
Periconceptional folic acid use prevents both rare and common neural tube defects in China	3
Folic acid antagonist use before and during pregnancy and risk for selected birth defects	3
Comparison of DNA methylation patterns across tissue types in infants with tetralogy of Fallot	3
Dolutegravir and rat whole embryo culture	3
Terminal transverse limb defects with “nubbins”	3
Effect of buscopan, a compound that alleviates cramps, on the developing nervous system of the chick embryo	3
Placental transfer of 125iodinated humanized immunoglobulin G2Δa in the cynomolgus monkey	3
The risk of major structural birth defects associated with seasonal influenza vaccination during pregnancy: A population‐based cohort study	3
The effect of different concentrations of cerium oxide during pregnancy on ovarian follicle development in neonatal mice	3
Does it matter when I quit? Could I just cut down some? Links between trimester‐specific smoking amount, preterm birth, and low birth weight	3
Choline ameliorates ethanol induced alterations in tyrosine phosphorylation and distribution in detergent‐resistant membrane microdomains of L1 cell adhesion molecule in vivo	3
The possible effect of lactoferrin on the epigenetic characteristics of early mammalian embryos exposed to bisphenol A	3
Combined effects of maternal exposure to fungicides on behavioral development in F1‐generation mice: 2. Fixed‐dose study of thiabendazole	3
In vitro effects of citral on the human myometrium: Potential adjunct therapy to prevent preterm births	3
Leveraging a phenome‐wide approach to identify novel exposure‐birth defect associations: A proof of concept using maternal smoking and a spectrum of birth defects	3
Application of zebrafish in the study of craniomaxillofacial developmental anomalies	3
Paternal exposure to recreational drugs before conception and its effect on live‐born offspring: A scoping review	3
Maternal age and the prevalence of congenital heart defects in Europe, 1995–2015: A register‐based study	3
Proportion of critical congenital heart defects attributable to unhealthy prepregnancy body mass index among women with live births in Florida, 2005–2016	3
Methoxyacetic acid inhibits histone deacetylase and impairs axial elongation morphogenesis of mouse gastruloids in a retinoic acid signaling‐dependent manner	3
Pre‐pregnancy dietary arsenic consumption among women in the United States	3
Describing characteristics of adults with and without congenital heart defects hospitalized with COVID‐19	3
Prenatal diagnosis of Proteus syndrome: Diagnosis of an AKT1 mutation from amniocytes	3
Health‐related quality of life after 50 years in individuals with thalidomide embryopathy: Evidence from a German cross‐sectional survey	3
Prevalence of vascular disruption anomalies and association with young maternal age: A EUROCAT study to compare the United Kingdom with other European countries	3