Birth Defects Research

Article	Citations
Projected impact of mandatory food fortification with folic acid on neurosurgical capacity needed for treating spina bifida in Ethiopia	22
Transgenerational adverse effects of valproate? A patient report from 90 affected families	21
A global update on the status of prevention of folic acid‐preventable spina bifida and anencephaly in year 2020: 30‐Year anniversary of gaining knowledge about folic acid's prevention potential for ne	18
Disparities in insurance coverage among hospitalized adult congenital heart disease patients before and after the Affordable Care Act	18
Pregnancy and infant outcomes by trimester of SARS‐CoV‐2 infection in pregnancy–SET‐NET, 22 jurisdictions, January 25, 2020–December 31, 2020	16
Academic achievement and needs of school‐aged children born with selected congenital anomalies: A systematic review and meta‐analysis	16
European trends in mortality in children with congenital anomalies: 2000–2015	16
First trimester COVID‐19 and the risk of major congenital malformations–International Registry of Coronavirus Exposure in Pregnancy	16
Prevalence of structural birth defects among infants with Down syndrome, 2013–2017: A US population‐based study	15
Examination of cortically projecting cholinergic neurons following exercise and environmental intervention in a rodent model of fetal alcohol spectrum disorders	15
Prenatal exposure to atrazine induces cryptorchidism and hypospadias in F1 male mouse offspring	15
A life‐table analysis of the intrauterine fate of malformed human embryos and fetuses	14
Exposures influencing the developing central autonomic nervous system	14
Maternal ethnicity and the prevalence of British pregnancies affected by neural tube defects	13
Perfluorooctanoic acid inhibits the maturation rate of mouse oocytes cultured in vitro by triggering mitochondrial and DNA damage	13
A novel human stem cell‐based biomarker assay for in vitro assessment of developmental toxicity	13
Prevalence of critical congenital heart defects and selected co‐occurring congenital anomalies, 2014–2018: A U.S. population‐based study	13
Prenatal developmental toxicity of alkyl dimethyl benzyl ammonium chloride and didecyl dimethyl ammonium chloride in CD rats and New Zealand White rabbits	12
Resveratrol ameliorates toxic effects of cadmium on placental development in mouse placenta and human trophoblast cells	12
Developmental safety of nirmatrelvir in zebrafish (Danio rerio) embryos	12
Developmental toxicity induced by triclosan exposure in zebrafish embryos	12
Maternal age and the prevalence of congenital heart defects in Europe, 1995–2015: A register‐based study	12
Maternal biomarkers for early prediction of the neural tube defects pregnancies	11
Prevalence and mortality among children with anorectal malformation: A multi‐country analysis	11
Fetal exposure to tofacitinib during the first trimester: A healthy newborn case report	10

Prevalence of congenital heart defects in Europe, 2008–2015: A registry‐based study	10
Yolk sac development, function and role in rodent pregnancy	9
Belimumab use during pregnancy: Interim results of the belimumab pregnancy registry	9
Moderate intensity aerobic exercise during pregnancy and 1‐month infant Morphometry	9
Modification of the association between diabetes and birth defects by obesity, National Birth Defects Prevention Study, 1997–2011	9
Survival of infants born with esophageal atresia among 24 international birth defects surveillance programs	9
Toward better assessments of developmental toxicity using stem cell‐based in vitro embryogenesis models	8
Prevalence of neural tube defects, maternal HIV status, and antiretroviral therapy from a hospital‐based birth defect surveillance in Kampala, Uganda	8
In‐utero cannabis exposure and long‐term psychiatric and neurodevelopmental outcomes: The limitations of existing literature and recommendations for future research	8
Gastroschisis in Ontario, Canada: 2012–2018	8
Clinical and neurodevelopmental outcomes based on brain imaging studies in a Colombian cohort of children with probable antenatal Zika virus exposure	8
Behavioral and neuroinflammatory changes caused by glyphosate: Base herbicide in mice offspring	8
Evaluating the proportion of isolated cases among a spectrum of birth defects in a population‐based registry	8
Melatonin inhibits embryonic rat H9c2 cells growth through induction of apoptosis and cell cycle arrest via PI3K‐AKT signaling pathway	8
Gene–environment interactions between air pollution and biotransformation enzymes and risk of birth defects	8
Maternal exposure to hydroxychloroquine and birth defects	8
Review of the state of science and evaluation of currently available in silico prediction models for reproductive and developmental toxicity: A case study on pesticides	8
Maternotoxicity and fetotoxicity in Rattus norvegicus albinus exposed to tramadol during the late phase of pregnancy	8
The accuracy of hospital discharge data in recording major congenital anomalies in Australia	7
Zika virus as a cause of birth defects: Were the teratogenic effects of Zika virus missed for decades?	7
Re‐sequencing of candidate genes FOXF1, HSPA6, HAAO, and KYNU in 522 individuals with VATER/VACTERL, VACTER/VACTERL	7
Relationship between achieving Sustainable Development Goals and promoting optimal care and prevention of birth defects globally	7
Conjoined twins and conjoined triplets: At the heart of the matter	7
Comparison of DNA methylation patterns across tissue types in infants with tetralogy of Fallot	7
Global birth defects app: An innovative tool for describing and coding congenital anomalies at birth in low resource settings	7
Quantitative in vitro to in vivo extrapolation for developmental toxicity potency of valproic acid analogues	7
Proportion of critical congenital heart defects attributable to unhealthy prepregnancy body mass index among women with live births in Florida, 2005–2016	7
No developmental toxicity observed with dolutegravir in rat whole embryo culture	7
Malarial PI4K inhibitor induced diaphragmatic hernias in rat: Potential link with mammalian kinase inhibition	7
Post‐traumatic stress disorder, anxiety, and depression among adults with congenital heart defects	7
Readability, understandability, and quality of retinopathy of prematurity information on the web	7
Cardiovascular function during early development is suppressed by cinnamon flavored, nicotine‐free, electronic cigarette vapor	6
The effects of in ovo administered bisphenol A on tibial growth plate histology in chicken	6
Gamma aminobutyric acid signaling disturbances and altered astrocytic morphology associated with Bisphenol A induced cognitive impairments in rat offspring	6
Does it matter when I quit? Could I just cut down some? Links between trimester‐specific smoking amount, preterm birth, and low birth weight	6
Myelomeningocele genotype–phenotype correlation findings in cilia, HH, PCP, and WNT signaling pathways	6
National population‐based estimates for major birth defects, 2016–2020	6
Exposure to alirocumab during the first trimester of pregnancy: A case report	6
Leveraging a phenome‐wide approach to identify novel exposure‐birth defect associations: A proof of concept using maternal smoking and a spectrum of birth defects	6
Prenatal epigenetic factors are predisposing for neurodevelopmental disorders—Considering placenta as a model	6
Regulation of Oct4 in stem cells and neural crest cells	6
Reproductive toxicity assessment of alkyl dimethyl benzyl ammonium chloride and didecyl dimethyl ammonium chloride in CD® rats	6
Limited surface examination to evaluate potential teratogens in a resource‐limited setting	6
Application of zebrafish in the study of craniomaxillofacial developmental anomalies	6
Maternal cigarette smoking and alcohol consumption and congenital diaphragmatic hernia	6
Concomitant genetic defects potentiate the adverse impact of prenatal alcohol exposure on cardiac outflow tract maturation	6
Structural changes, increased hypoxia, and oxidative DNA damage in placenta due to maternal smokeless tobacco use	6
Prevalence of vascular disruption anomalies and association with young maternal age: A EUROCAT study to compare the United Kingdom with other European countries	6
In vitro effects of citral on the human myometrium: Potential adjunct therapy to prevent preterm births	6
Identifying the landscape of developmental toxicity new approach methodologies	6

Teratogenesis and the epigenetic programming of congenital defects: Why paternal exposures matter	6
Investigation of developmental toxicity of favipiravir on fetal bone and embryonic development	5
Biological impacts of the green synthesized silver nanoparticles on the pregnant albino rats and their fetuses	5
Terminal transverse limb defects with “nubbins”	5
Biallelic THOC6 pathogenic variants: Prenatal phenotype and review of the literature	5
Systematic assessment of quaternary ammonium compounds for the potential to elicit developmental and reproductive effects	5
Describing characteristics of adults with and without congenital heart defects hospitalized with COVID‐19	5
Single‐cell profiling for advancing birth defects research and prevention	5
Parietal bone agenesis and athelia in retinoic acid embryopathy: An expansion of the phenotype	5
Prenatal alcohol exposure can be determined from baby teeth: Proof of concept	5
Using high throughput screens to predict miscarriages with placental stem cells and long‐term stress effects with embryonic stem cells	5
Perinatal nicotine exposure alters lung development and induces HMGB1‐RAGE expression in neonatal mice	5
The effect of different concentrations of cerium oxide during pregnancy on ovarian follicle development in neonatal mice	5
A putative adverse outcome network for neonatal mortality and lower birth weight in rodents: Applicability to per‐ and polyfluoroalkyl substances and relevance to human health	5
Patterns of multiple congenital anomalies in the National Birth Defect Prevention Study: Challenges and insights	5
Maternal diabetes as a teratogenic factor for congenital heart defects in infants of diabetic mothers	5
Viewing teratogens through the lens of nicotinamide adenine dinucleotide (NAD+)	5
Final results from the ribavirin pregnancy registry, 2004–2020	5
Early‐lifeexposure to alcohol and the risk ofalcohol‐inducedliver disease in adulthood	5
The risk of major structural birth defects associated with seasonal influenza vaccination during pregnancy: A population‐based cohort study	5
Development and evaluation of standardized pregnancy identification and trimester distribution algorithms in U.S. IBM MarketScan® Commercial and Medicaid data	4
Causes of neonatal and postneonatal death among infants with birth defects in Texas	4
Dose range finding approach for rodent preweaning juvenile animal studies	4
A multi‐program analysis of cleft lip with cleft palate prevalence and mortality using data from 22 International Clearinghouse for Birth Defects Surveillance and Research programs, 1974–2014	4
School age educational outcomes of infants born with congenital diaphragmatic hernia	4
The pro‐apoptotic Bax gene modifies susceptibility to craniofacial dysmorphology following gastrulation‐stage alcohol exposure	4
Amelioration of silymarin against cadmium‐induced toxicity in pregnant rats and their fetuses	4
Trends in prevalence of gastroschisis in Brazil from 2007 to 2020: A national population‐based cross‐sectional study	4
COG6‐CDG: Novel variants and novel malformation	4
Comparison of germ cell differentiation of rat testis fragments cultured in knockout serum replacement versus Albumax™ I	4
Health‐related quality of life after 50 years in individuals with thalidomide embryopathy: Evidence from a German cross‐sectional survey	4
Gestational exposure to triphenyl phosphate induces epigenetic modifications in C57Bl/6 fetal liver	4
Effect of chlorpyrifos and its metabolites on skeletal system development of chick embryo	4
Role of coxsackie‐adenovirus receptor in cardiac development and pathogenesis of congenital heart disease	4
Preclinical development of a novel Group B Streptococcus (GBS) vaccine candidate for maternal immunization based upon the alpha‐like protein family of GBS surfa	4
A spatial analysis of birth defects in Texas, 1999–2011	4
Agreement between maternal report and medical records on use of medications during early pregnancy in New York	4
Physician hesitancy to recommend COVID‐19 vaccination in pregnancy as a cause of maternal deaths ‐ Robert Brent was prescient	4
Translational potential of hiPSCs in predictive modeling of heart development and disease	4
A cross‐sectional study of brownfields and birth defects	4
Effect of buscopan, a compound that alleviates cramps, on the developing nervous system of the chick embryo	4
Maternal micronutrient deficiency and congenital heart disease risk: A systematic review of observational studies	4
Characteristics and first‐year mortality, by lesion level, among infants with spina bifida in the New York State Birth Defects Registry, 2008–2017	4
Multiple subtypes of coxsackievirus group B can cause congenital heart disease	4
Co‐occurrence of congenital anomalies by maternal race/ethnicity among infants and fetuses with Down syndrome, 2013–2017: A U.S. population‐based analysis	4
Periconceptional folic acid use prevents both rare and common neural tube defects in China	4
Distance from home to birth hospital, transfer, and mortality in neonates with hypoplastic left heart syndrome in California	4
Medicaid healthcare expenditures for infants with birth defects potentially related to Zika virus infection in North Carolina, 2011–2016	3
Alobar holoprosencephaly in mining‐related areas of the Eastern region of the Democratic Republic of the Congo: A case series	3
Pregnancy outcome after first trimester exposure to vortioxetine: A case series	3
The association of nausea and vomiting of pregnancy, its treatments, and select birth defects: Findings from the National Birth Defect Prevention Study	3
The miR‐17‐92 cluster in cardiac health and disease	3
Prepregnancy body mass index and spina bifida: Potential contributions of bias	3
Reproductive and neurobehavioral effects of maternal exposure to dinotefuran in the F1‐generation mice	3
Pandemic stressors and vaccine hesitancy among young, pregnant Black people: A qualitative study of health disparities during a global pandemic	3
Ascertainment of malformations in pregnancy registries: Lessons learned in the North American AED Pregnancy Registry	3
Probing single ventricle heart defects with patient‐derived induced pluripotent stem cells and emerging technologies	3
Cannabis during pregnancy: A way to transfer an impairment to later life	3
Comparison of inherited neural tube defects in companion animals and livestock	3
Prenatal immobility stress: Relationship with oxidative stress, inflammation, apoptosis, and intrauterine growth restriction in rats	3
Lesion‐specific mortality due to congenital heart disease in U.S. adults from 1999 to 2017	3
Periconceptional nonsteroidal anti‐inflammatory drug use, folic acid intake, and the risk of spina bifida	3
Abnormal placental cord insertion, hypertensive disorders of pregnancy and birth length may be involved in development of hypospadias in male fetuses	3
Prepregnancy exposure to dietary arsenic and congenital heart defects	3
Maternal dietary caffeine consumption and risk of birth defects in the National Birth Defects Prevention Study, 1997–2011	3
Developmental toxicity of remdesivir, an anti‐COVID‐19 drug, is implicated by in vitro assays using morphogenetic embryoid bodies of mouse and human pluripotent stem cells	3
Introduction to “Stem Cells” special issue	3
Evidence for a cluster of rare birth defects in the Ain department (France)	3
Neural tube defects prevalence does not increase after modification of the folic acid fortification program in Chile	3
The possible effect of lactoferrin on the epigenetic characteristics of early mammalian embryos exposed to bisphenol A	3
Abnormal growth and morphogenesis of placenta at term is linked to adverse fetal development after perigestational alcohol consumption up to early gestation in mouse	3
Congenital cytomegalovirus surveillance in the United States	3
Dolutegravir and rat whole embryo culture	3
Risk of birth defects by pregestational type 1 or type 2 diabetes: National Birth Defects Prevention Study, 1997–2011	3
Tris(4‐chlorophenyl)methane and tris(4‐chlorophenyl)methanol disrupt pancreatic organogenesis and gene expression in zebrafish embryos	3
Association between maternal body mass index and congenital anomalies: A case‐control study in Tuscany (Italy)	3
The study of expression levels of DNA methylation regulators in patients affected with congenital heart defects (CHDs)	2
Folic acid supplementation in women of childbearing age with epilepsy: No association with type or number of antiepileptic drugs	2
Safety of prenatal opioid analgesics: Do results differ between public health insurance beneficiary and population‐based cohorts?	2
Genetic predisposition to the development of congenital heart diseases: Role of xenobiotic biotransformation genes	2

Venlafaxine prescription claims among insured women of reproductive age and pregnant women, 2011–2016	2
Early pregnancy vitamin D status and risk of select congenital anomalies in the National Birth Defects Prevention Study	2
Sex‐related beneficial effects of exercise on cardiac function and rhythm in autistic rats	2
Developmental toxicity induced by brodifacoum in zebrafish (Danio rerio) early life stages	2
Stem cell‐based region‐specific brain organoids: Novel models to understand neurodevelopmental defects	2
Oxidative balance scores and neural crest cell‐related congenital anomalies	2
Hdac1 and Hdac2 positively regulate Notch1 gain‐of‐function pathogenic signaling in committed osteoblasts of male mice	2
Assessment of postnatal femur development in Wistar Han rats	2
Epigenetic implications in maternal diabetes and metabolic syndrome‐associated risk of orofacial clefts	2
Effects of ketamine‐induced H3K9 hypoacetylation during pregnancy on cardiogenesis of mouse offspring	2
Exome sequencing identifies variants in infants with sacral agenesis	2
Animal evidence considered in determination of cannabis smoke and Δ9‐tetrahydrocannabinol as causing reproductive toxicity (developmental endpoint); Part I. Somatic development	2
Hypothesized pathogenesis of acardius acephalus, acormus, amorphus, anceps, acardiac edema, single umbilical artery, and pump twin risk prediction	2
Neighborhood location and nutritional resources as a risk factor for congenital heart disease in the fetus	2
Investigation of the risk factors of anorectal malformations	2
Areca nut and smokeless tobacco exposure induces micronucleus, other nuclear abnormalities and cytotoxicity in early chick embryo	2
A systematic review and meta‐analysis of school and cognitive function domains of health‐related quality of life measures for children and young adults with congenital heart disease	2
Vision outcomes in children with fetal alcohol spectrum disorders	2
Effect of tramadol hydrochloride on neural tube development in 48‐hr chick embryos: Argyrophilic nucleolar organizing region and genetic analysis study	2
The quality and the accuracy of codes for terminations of pregnancy for fetal anomalies recorded in hospital databases in three countries in northern Europe	2
2021 U.S. Virgin Islands Zika health brigade: Providing recommended pediatric health screenings for children born to mothers with laboratory evidence of possible Zika virus infection during pregnancy	2
DNA methylation profile of lip tissue from congenital nonsyndromic cleft lip and palate patients by whole‐genome bisulfite sequencing	2
Survival of infants and children born with severe microcephaly, Texas, 1999–2015	2
Maternal–fetal safety evaluation of an aqueous extract of Casearia sylvestris leaves in rats	2
Gestational exposure to continuous light impairs the development of the female reproductive system in adult Wistar rat offspring	2
Hypothesis: By‐products of vascular disruption carried in the CSF affect prenatal brain development	2
Lithium‐induced overexpression of β‐catenin delays murine palatal shelf elevation by Cdc‐42 mediated F‐actin remodeling in mesenchymal cells	2
Preconception paternal comorbidities and offspring birth defects: Analysis of a large national data set	2
Real‐world prevalence, time of diagnosis, and co‐occurrence patterns of birth defects in live‐born infants, 2014–2020: A health administrative database study in Japan	2
An overview of developmental dysregulation of autonomic control in infants	2
Elevated risk for developmental disabilities in children with congenital heart defects	2
Combined effects of maternal exposure to fungicides on behavioral development in F1‐generation mice: 3. Fixed‐dose study of imazalil	2
Periconceptional use of vitamin A and the risk of giving birth to a child with nonsyndromic orofacial clefts—A meta‐analysis	2
AmicroRNAor messengerRNApoint of departure estimates an apical endpoint point of departure in a rat developmental toxicity model	2
A novel clinic structure for exposure counseling during pregnancy	2
Correlation between COVID‐19 infection and fetal situs inversus	2
Methods for analyzing infant heart rate variability: A preliminary study	2
Verbascoside‐enriched fraction from Buddleja cordata Kunth ameliorates the effects of diabetic embryopathy in an animal model	2
Use of computational toxicology models to predict toxicological points of departure: A case study with triazine herbicides	2
High‐throughput detection of craniofacial defects in fluorescent zebrafish	2
Maternal first trimester COVID‐19 vaccination and risk of major non‐genetic congenital anomalies	2
Interpregnancy interval and prevalence of selected birth defects: A multistate study	2
Molecular insights of KMT2D and clinical aspects of Kabuki syndrome type 1	2
Radio frequency ablation for the intrauterine treatment of giant placental chorioangioma associated with fetal compromise: A case report	2
Cannabidiol impairs neural tube closure in mouse whole embryo culture	2
Gastroschisis prevalence patterns in 27 surveillance programs from 24 countries, International Clearinghouse for Birth Defects Surveillance and Research, 1980–2017	2
Sodium valproate exposure influences the expression of pparg in the zebrafish model	2
Amelia and phocomelia in Finland: Characteristics and prevalences in a nationwide population‐based study	2
Population‐based prevalence and trend of birth defects in Costa Rica from 2000 to 2019	2
Protective effect of quercetin on fetal development and congenital skeletal anomalies against exposure of pregnant Wistar rats to crude oil vapor	2
Acardiac twin pregnancies part VI: Why does acardiac twinning occur only in the first trimester?	2
Associations between maternal reports of periconceptional fever from miscellaneous causes and structural birth defects	2
Genotype–phenotype spectrum and correlations in Xia‐Gibbs syndrome: Report of five novel cases and literature review	2
Construction and analysis of a joint diagnostic model of machine learning for cryptorchidism based on single‐cell sequencing	2
Evaluation of p21 expression and related autism‐like behavior in Bisphenol‐A exposed offspring of Wistar albino rats	2
Nongenetic risk factors for infantile cataracts: Systematic review of observational studies	2
Determination and analysis of sex ratios in heme oxygenase 1 gene targeted mouse embryos	2
Cutis marmorata telangiectatica congenita with isolated lower limb defect and angiokeratoma	2
Maternal first trimester metabolic profile in pregnancies with transposition of the great arteries	2