Science Immunology

(The TQCC of Science Immunology is 72. The table below lists those papers that are above that threshold based on CrossRef citation counts. The publications cover those that have been published in the past four years, i.e., from 2019-03-01 to 2023-03-01.)
Distinct antibody and memory B cell responses in SARS-CoV-2 naïve and recovered individuals after mRNA vaccination411
Structure and function of the immune system in the spleen350
Location, location, location: Tissue resident memory T cells in mice and humans293
An immune clock of human pregnancy275
Immune responses at the maternal-fetal interface273
Defining the emergence of myeloid-derived suppressor cells in breast cancer using single-cell transcriptomics188
Intratumoral activation of the necroptotic pathway components RIPK1 and RIPK3 potentiates antitumor immunity178
Generation and persistence of human tissue-resident memory T cells in lung transplantation157
The anatomy and immunology of vasculature in the central nervous system143
Engineering nanoparticles to locally activate T cells in the tumor microenvironment142
Conventional DCs sample and present myelin antigens in the healthy CNS and allow parenchymal T cell entry to initiate neuroinflammation136
Discordant neutralizing antibody and T cell responses in asymptomatic and mild SARS-CoV-2 infection133
Stromal cells maintain immune cell homeostasis in adipose tissue via production of interleukin-33132
Distinct immunocyte-promoting and adipocyte-generating stromal components coordinate adipose tissue immune and metabolic tenors128
Human CD4 + CD103 + cutaneous resident memory T cells are found in the circulation of healthy individuals127
Meningeal γδ T cell–derived IL-17 controls synaptic plasticity and short-term memory125
Inflammatory profiles across the spectrum of disease reveal a distinct role for GM-CSF in severe COVID-19122
Neutrophil cytoplasts induce T H 17 differentiation and skew inflammation toward neutrophilia in severe asthma121
A lipid-encapsulated mRNA encoding a potently neutralizing human monoclonal antibody protects against chikungunya infection119
Tumor-infiltrating human CD4 + regulatory T cells display a distinct TCR repertoire and exhibit tumor and neoantigen reactivity117
Human IFN-γ immunity to mycobacteria is governed by both IL-12 and IL-23116
Islet-reactive CD8 + T cell frequencies in the pancreas, but not in blood, distinguish type 1 diabetic patients from healthy donors116
VEGF-A drives TOX-dependent T cell exhaustion in anti–PD-1–resistant microsatellite stable colorectal cancers112
Tuberculosis and impaired IL-23–dependent IFN-γ immunity in humans homozygous for a common TYK2 missense variant109
Human natural killer cells mediate adaptive immunity to viral antigens100
Human inborn errors of immunity: An expanding universe96
A recessive form of hyper-IgE syndrome by disruption of ZNF341-dependent STAT3 transcription and activity92
Gasdermin D activity in inflammation and host defense88
Interleukin-36γ–producing macrophages drive IL-17–mediated fibrosis83
Transplanting organs from pigs to humans81
Neutrophil extracellular traps drive inflammatory pathogenesis in malaria79
Multidimensional imaging provides evidence for down-regulation of T cell effector function by MDSC in human cancer tissue77
CTLA-4–mediated transendocytosis of costimulatory molecules primarily targets migratory dendritic cells75
Interleukin-17 receptor D constitutes an alternative receptor for interleukin-17A important in psoriasis-like skin inflammation73
Ketogenic diet activates protective γδ T cell responses against influenza virus infection73
Incomplete genetic reconstitution of B cell pools contributes to prolonged immunosuppression after measles72
Interfacial actin protrusions mechanically enhance killing by cytotoxic T cells72