OOIR: Observatory of International Research

Papers

(The H4-Index of Science Immunology is 70. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-02-01 to 2025-02-01.)

Article	Citations
Anti–immune complex antibodies are elicited during repeated immunization with HIV Env immunogens	554
Oncogenic KRAS drives immunosuppression of colorectal cancer by impairing DDX60-mediated dsRNA accumulation and viral mimicry	485
Cytotoxic granzyme C–expressing ILC1s contribute to antitumor immunity and neonatal autoimmunity	413
Germline biallelic mutation affecting the transcription factor Helios causes pleiotropic defects of immunity	359
A diverse fibroblastic stromal cell landscape in the spleen directs tissue homeostasis and immunity	316
ExtrathymicAire-expressing cells support maternal-fetal tolerance	269
Mast cells help organize the Peyer’s patch niche for induction of IgA responses	248
Welcoming c-MAF to the macrophage transcription factor VAM-ily	236
cGAS-activated endothelial cell–T cell cross-talk initiates tertiary lymphoid structure formation	206
T cell help induces Myc transcriptional bursts in germinal center B cells during positive selection	197
Integrin α3 promotes T _H 17 cell polarization and extravasation during autoimmune neuroinflammation	189
Type 2 immune predisposition results in accelerated neutrophil aging causing susceptibility to bacterial infection	187
Central memory T cells are the most effective precursors of resident memory T cells in human skin	180
Resident T _H 2 cells orchestrate adipose tissue remodeling at a site adjacent to infection	177
Activation of CD81 ⁺ skin ILC2s by cold-sensing TRPM8 ⁺ neuron-derived signals maintains cutaneous thermal homeostasis	172
Two subsets of human marginal zone B cells resolved by global analysis of lymphoid tissues and blood	167
Lung dendritic cells migrate to the spleen to prime long-lived TCF1 ^hi memory CD8 ⁺ T cell precursors after influenza infection	166
Single-cell NAD(H) levels predict clonal lymphocyte expansion dynamics	154
T _regs and inflammation—bring it on!	150
The HLA advantage: Why COVID-19 benched you but not your co-worker	148
Getting toGether in Germinal centers	145
Plasmablasts from the past: Nostalgic B cells can’t let go	145
MTHFD2, metabolic mastermind of CD4 ⁺ T cell destiny	145
A T-rojan horse strategy for cancer immunotherapy	145
It’s good to have Gremlins in the zone	142

Editors' Choice	140
Bearing a grudge—How human natural killer cells remember past insults	139
Orientation-dependent CD45 inhibition with viral and engineered ligands	137
A three-stage developmental pathway for human Vγ9Vδ2 T cells within the postnatal thymus	135
Of bats and men: Immunomodulatory treatment options for COVID-19 guided by the immunopathology of SARS-CoV-2 infection	132
CAR-ving away OX40L with engineered T _regs	132
Assembly of a spatial circuit of T-bet–expressing T and B lymphocytes is required for antiviral humoral immunity	128
Aire drives steroid hormone biosynthesis by medullary thymic epithelial cells	128
IL-12 regulates type 3 immunity through interfollicular keratinocytes in psoriasiform inflammation	125
Virtual memory T cells orchestrate extralymphoid responses conducive to resident memory	125
Pannexin 1 drives efficient epithelial repair after tissue injury	124
Single-cell analysis of anti-BCMA CAR T cell therapy in patients with central nervous system autoimmunity	116
Selfish antibodies target auto-antigens in cancer	115
The cold truth about TCR structure	113
A SPARC-ling link to inflammaging	112
The trouble with TRIBbles: TRIB3 blocks CD8 T cell homing to colorectal cancers	112
Promoting (and targeting) alternative expression	111
The Benjamin Button effect on stem cells: Reversing the clock on aging immunity	105
RORγt-lineage APCs: The Aire apparent	104
Genome-wide screening identifies Trim33 as an essential regulator of dendritic cell differentiation	104
DPP9 deficiency: An inflammasomopathy that can be rescued by lowering NLRP1/IL-1 signaling	103
Clostridium septicum α-toxin activates the NLRP3 inflammasome by engaging GPI-anchored proteins	99
B cells require DOCK8 to elicit and integrate T cell help when antigen is limiting	96
Schlafen 11 triggers innate immune responses through its ribonuclease activity upon detection of single-stranded DNA	94
Antigen-presenting cell activation requires intrinsic and extrinsic STING signaling after the phagocytosis of DNA-damaged cells	92
Immune recall improves antibody durability and breadth to SARS-CoV-2 variants	91
Erratum for the Research Article “GGNBP2 regulates MDA5 sensing triggered by self double-stranded RNA following loss of ADAR1 editing” by J. E. Heraud-Farlow et al .	91
Immune checkpoint blockade sensitivity and progression-free survival associates with baseline CD8 ⁺ T cell clone size and cytotoxicity	91
Naive human B cells engage the receptor binding domain of SARS-CoV-2, variants of concern, and related sarbecoviruses	89
XIAP restrains TNF-driven intestinal inflammation and dysbiosis by promoting innate immune responses of Paneth and dendritic cells	83
Waking the sleeping giant: Single-stranded DNA binds Schlafen 11 to initiate innate immune responses	82
TCR-engineered iNKT cells induce robust antitumor response by dual targeting cancer and suppressive myeloid cells	80
Overexpression of Malat1 drives metastasis through inflammatory reprogramming of the tumor microenvironment	80
Pharmacological activation of STING blocks SARS-CoV-2 infection	77
TGFβ prevents IgE-mediated allergic disease by restraining T follicular helper 2 differentiation	77
LXR signaling controls homeostatic dendritic cell maturation	75
Targeting T cell plasticity in kidney and gut inflammation by pooled single-cell CRISPR screening	75
Ikaros is a principal regulator of Aire ⁺ mTEC homeostasis, thymic mimetic cell diversity, and central tolerance	75
Myeloid cell tropism enables MHC-E–restricted CD8 ⁺ T cell priming and vaccine efficacy by the RhCMV/SIV vaccine	75
Clonally expanded CD38 ^hi cytotoxic CD8 T cells define the T cell infiltrate in checkpoint inhibitor–associated arthritis	74
A tetraspecific engager armed with a non-alpha IL-2 variant harnesses natural killer cells against B cell non-Hodgkin lymphoma	74
Regulatory T cells promote innate inflammation after skin barrier breach via TGF-β activation	73
IL-1R1–dependent signaling coordinates epithelial regeneration in response to intestinal damage	72
PD-1 blockade and vaccination provide therapeutic benefit against SIV by inducing broad and functional CD8 ⁺ T cells in lymphoid tissue	72
A yeast-expressed RBD-based SARS-CoV-2 vaccine formulated with 3M-052-alum adjuvant promotes protective efficacy in non-human primates	71