Science Immunology

Papers
(The H4-Index of Science Immunology is 68. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)
ArticleCitations
Anti–immune complex antibodies are elicited during repeated immunization with HIV Env immunogens571
Linking vaccine adjuvant mechanisms of action to function494
Germline biallelic mutation affecting the transcription factor Helios causes pleiotropic defects of immunity441
Cis interactions between CD2 and its ligands on T cells are required for T cell activation374
Macrophage compartmentalization in the brain and cerebrospinal fluid system326
The gene regulatory basis of bystander activation in CD8 + T cells320
Mast cells help organize the Peyer’s patch niche for induction of IgA responses260
Mast cell–derived BH4 and serotonin are critical mediators of postoperative pain252
Sulfated bile acid is a host-derived ligand for MAIT cells243
Welcoming c-MAF to the macrophage transcription factor VAM-ily220
T cell help induces Myc transcriptional bursts in germinal center B cells during positive selection209
Integrin α3 promotes T H 17 cell polarization and extravasation during autoimmune neuroinflammation190
STING-activating nanoparticles normalize the vascular-immune interface to potentiate cancer immunotherapy179
The acid-sensing receptor GPR65 on tumor macrophages drives tumor growth in obesity177
Central memory T cells are the most effective precursors of resident memory T cells in human skin173
Ikaros is a principal regulator of Aire + mTEC homeostasis, thymic mimetic cell diversity, and central tolerance172
Silent recognition of flagellins from human gut commensal bacteria by Toll-like receptor 5166
Type 2 immune predisposition results in accelerated neutrophil aging causing susceptibility to bacterial infection165
Resident T H 2 cells orchestrate adipose tissue remodeling at a site adjacent to infection160
Single-cell NAD(H) levels predict clonal lymphocyte expansion dynamics159
The Benjamin Button effect on stem cells: Reversing the clock on aging immunity159
T regs and inflammation—bring it on!157
The HLA advantage: Why COVID-19 benched you but not your co-worker154
MTHFD2, metabolic mastermind of CD4 + T cell destiny153
Plasmablasts from the past: Nostalgic B cells can’t let go148
A T-rojan horse strategy for cancer immunotherapy146
It’s good to have Gremlins in the zone142
Bearing a grudge—How human natural killer cells remember past insults140
A three-stage developmental pathway for human Vγ9Vδ2 T cells within the postnatal thymus134
Orientation-dependent CD45 inhibition with viral and engineered ligands134
CAR-ving away OX40L with engineered T regs130
Single-cell analysis of anti-BCMA CAR T cell therapy in patients with central nervous system autoimmunity128
Immune recall improves antibody durability and breadth to SARS-CoV-2 variants127
Fractionating a COVID-19 Ad5-vectored vaccine improves virus-specific immunity126
Immune memory from SARS-CoV-2 infection in hamsters provides variant-independent protection but still allows virus transmission125
HLA-E–restricted SARS-CoV-2–specific T cells from convalescent COVID-19 patients suppress virus replication despite HLA class Ia down-regulation121
The cold truth about TCR structure116
Selfish antibodies target auto-antigens in cancer116
A SPARC-ling link to inflammaging113
The trouble with TRIBbles: TRIB3 blocks CD8 T cell homing to colorectal cancers112
Promoting (and targeting) alternative expression110
A yeast-expressed RBD-based SARS-CoV-2 vaccine formulated with 3M-052-alum adjuvant promotes protective efficacy in non-human primates109
Getting toGether in Germinal centers106
Is one lymphocyte’s brake another lymphocyte’s gas?101
IL-4 induces CD22 expression to restrain the effector program of virtual memory T cells98
Afraid of needles? Try lotion: Engineering skin commensals for vaccination96
Genome-wide screening identifies Trim33 as an essential regulator of dendritic cell differentiation95
RORγt-lineage APCs: The Aire apparent94
Immune checkpoint blockade sensitivity and progression-free survival associates with baseline CD8 + T cell clone size and cytotoxicity92
DPP9 deficiency: An inflammasomopathy that can be rescued by lowering NLRP1/IL-1 signaling92
BMP signaling in the intestinal epithelium drives a critical feedback loop to restrain IL-13–driven tuft cell hyperplasia91
Oxidized thioredoxin-1 restrains the NLRP1 inflammasome86
Regulatory T cells promote innate inflammation after skin barrier breach via TGF-β activation85
B cells require DOCK8 to elicit and integrate T cell help when antigen is limiting82
Erratum for the Research Article “GGNBP2 regulates MDA5 sensing triggered by self double-stranded RNA following loss of ADAR1 editing” by J. E. Heraud-Farlow et al .81
Antigen-presenting cell activation requires intrinsic and extrinsic STING signaling after the phagocytosis of DNA-damaged cells81
Naive human B cells engage the receptor binding domain of SARS-CoV-2, variants of concern, and related sarbecoviruses80
Cytotoxic granzyme C–expressing ILC1s contribute to antitumor immunity and neonatal autoimmunity80
Virtual memory T cells orchestrate extralymphoid responses conducive to resident memory77
Targeting T cell plasticity in kidney and gut inflammation by pooled single-cell CRISPR screening76
TGFβ prevents IgE-mediated allergic disease by restraining T follicular helper 2 differentiation75
Waking the sleeping giant: Single-stranded DNA binds Schlafen 11 to initiate innate immune responses75
A tetraspecific engager armed with a non-alpha IL-2 variant harnesses natural killer cells against B cell non-Hodgkin lymphoma72
DNMT1 inhibition reprograms T cells to NK-like cells with potent antitumor activity72
PD-1 blockade and vaccination provide therapeutic benefit against SIV by inducing broad and functional CD8 + T cells in lymphoid tissue70
Two-dose priming immunization amplifies humoral immunity by synchronizing vaccine delivery with the germinal center response69
SNIPR alert! Making T cells more precise killers68
Polyclonal expansion of TCR Vβ 21.3+CD4+and CD8+T cells is a hallmark of multisystem inflammatory syndrome in children68
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