OOIR: Observatory of International Research

Papers

(The H4-Index of Science Immunology is 69. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
The HLA advantage: Why COVID-19 benched you but not your co-worker	353
Is one lymphocyte’s brake another lymphocyte’s gas?	334
Waking the sleeping giant: Single-stranded DNA binds Schlafen 11 to initiate innate immune responses	317
Characterization of the mammalian prodefinitive angio-hematopoietic lineage	293
RORγt-lineage APCs: The Aire apparent	251
CLNS1A regulates genome stability and cell cycle progression to control CD4 T cell function and autoimmunity	204
Genome-wide screening identifies Trim33 as an essential regulator of dendritic cell differentiation	178
T cell help induces Myc transcriptional bursts in germinal center B cells during positive selection	174
Structural variation tunes apoptotic responses to drive immune escape in melanoma	156
Operation Nasal Vaccine—Lightning speed to counter COVID-19	136
The OAS–RNase L pathway: Insights from experiments of nature	136
Clonally expanded CD38 ^hi cytotoxic CD8 T cells define the T cell infiltrate in checkpoint inhibitor–associated arthritis	133
Aire drives steroid hormone biosynthesis by medullary thymic epithelial cells	131
Single-cell NAD(H) levels predict clonal lymphocyte expansion dynamics	131
Atlas of human gut-associated lymphoid tissue reveals immunomodulatory interactions of B cells	124
Single-cell analysis of anti-BCMA CAR T cell therapy in patients with central nervous system autoimmunity	123
HLA-E–restricted SARS-CoV-2–specific T cells from convalescent COVID-19 patients suppress virus replication despite HLA class Ia down-regulation	120
Antigen-presenting cell activation requires intrinsic and extrinsic STING signaling after the phagocytosis of DNA-damaged cells	119
DPP9 deficiency: An inflammasomopathy that can be rescued by lowering NLRP1/IL-1 signaling	117
Silent recognition of flagellins from human gut commensal bacteria by Toll-like receptor 5	116
Hypoxia-induced EGR1 remodels neutrophils to suppress antitumor immunity	115
DNA-damaging chemotherapy reshapes cardiac-resident macrophage composition and function	110
Immunogenomic cancer evolution: A framework to understand cancer immunosuppression	109
Neither naïve nor anergic, “autoimmune” not allergic	107
The rise of spatial TCR profiling: Emerging technologies and open challenges	106

Antibody-mediated immunity against lung cancer goes retro	106
SARS-CoV-2–specific T cells in unexposed adults display broad trafficking potential and cross-react with commensal antigens	103
Single-cell topographical profiling of the immune synapse reveals a biomechanical signature of cytotoxicity	101
Gluten induces rapid reprogramming of natural memory αβ and γδ intraepithelial T cells to induce cytotoxicity in celiac disease	101
Simultaneous priming of HIV broadly neutralizing antibody precursors to multiple epitopes by germline-targeting mRNA-LNP immunogens in mouse models	99
Allergen-induced airway matrix remodeling in mice can be prevented or reversed by targeting chitinase-like proteins	98
Class switch toward noninflammatory, spike-specific IgG4 antibodies after repeated SARS-CoV-2 mRNA vaccination	97
Obesity reshapes regulatory T cells in the visceral adipose tissue by disrupting cellular cholesterol homeostasis	92
CD103 fate mapping reveals that intestinal CD103⁻tissue-resident memory T cells are the primary responders to secondary infection	92
Group A Streptococcus induces CD1a-autoreactive T cells and promotes psoriatic inflammation	90
Luck gone cold: A trifecta of B cell mutations associates with cryoglobulinemia	89
Chimeric autoantibody receptor T cells clonally eliminate B cells producing autoantibodies against IFN-γ	89
CD39 ⁺ tissue-resident memory CD8 ⁺ T cells with a clonal overlap across compartments mediate antitumor immunity in breast cancer	88
B cells gone broad: A deep dive into SARS-CoV-2 antibody breadth	88
Erratum for the Research Article “TGF-β specifies T _FH versus T _H 17 cell fates in murine CD4	87
GGNBP2 regulates MDA5 sensing triggered by self double-stranded RNA following loss of ADAR1 editing	87
Dissection of the immune landscape in psoriatic arthritis defines immunoproteasome up-regulation in treatment resistance	85
Tissue origin and virus specificity shape human CD8 ⁺ T cell cytotoxicity	84
BCL6 is required for the thymic development of TCRαβ ⁺ CD8αα ⁺ intraepithelial lymphocyte lineage	82
Microbial energy metabolism fuels an intestinal macrophage niche in solitary isolated lymphoid tissues through purinergic signaling	82
Erratum for the Research Article “Claudins interact with LILRB immune inhibitory receptors to promote myeloid immunosuppression in cancer”	81
A breath of fresh AIR in novel CAR T cell design	80
The palmitoylation of gasdermin D directs its membrane translocation and pore formation during pyroptosis	79
Antigen-specific depletion of CD4 ⁺ T cells by CAR T cells reveals distinct roles of higher- and lower-affinity TCRs during autoimmunity	79
CD5 deletion enhances the antitumor activity of adoptive T cell therapies	79
Sustained CD28 costimulation is required for self-renewal and differentiation of TCF-1 ⁺ PD-1 ⁺ CD8 T cells	79
Epidermal growth factor receptor controls sex differences in lung type 2 responses to inhaled allergen	78
Staphylococcus aureus skin colonization promotes SLE-like autoimmune inflammation via neutrophil activation and the IL-23/IL-17 axis	78
Maternal allergy and neonatal RSV infection synergize via FcR-mediated allergen uptake to promote the development of asthma in early life	78
Dynamic STING repression orchestrates immune cell development and function	77
Unearthing the Rosetta Stone of public antibody responses	76
Gutsy memory T cells stand their ground against pathogens	76
Non-apoptotic FAS signaling controls mTOR activation and extrafollicular maturation in human B cells	75
SARS-CoV-2 spike conformation determines plasma neutralizing activity elicited by a wide panel of human vaccines	75
Exposure to BA.4/5 S protein drives neutralization of Omicron BA.1, BA.2, BA.2.12.1, and BA.4/5 in vaccine-experienced humans and mice	75
Myeloid OTULIN deficiency couples RIPK3-dependent cell death to Nlrp3 inflammasome activation and IL-1β secretion	74
Tissue-specific nonheritable influences drive endometrial immune system variation	74
Multimodal delineation of a layer of effector function among exhausted CD8 T cells in tumors	73
Intratumoral T _reg cell ablation elicits NK cell–mediated control of CD8 T cell–resistant tumors	72
IgE plasma cells are transcriptionally and functionally distinct from other isotypes	72
Neutrophils and macrophages drive TNF-induced lethality via TRIF/CD14-mediated responses	72
Group 2 innate lymphoid cells regulate nociceptive and gait functions of the peripheral nervous system	71
NKG2D-mediated detection of metabolically stressed hepatocytes by innate-like T cells is essential for initiation of NASH and fibrosis	70
Early human lung immune cell development and its role in epithelial cell fate	69
Dysregulation of γδ intraepithelial lymphocytes precedes Crohn’s disease–like ileitis	69