OOIR: Observatory of International Research

Papers

(The H4-Index of Science Immunology is 67. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
Waking the sleeping giant: Single-stranded DNA binds Schlafen 11 to initiate innate immune responses	497
T cell help induces Myc transcriptional bursts in germinal center B cells during positive selection	450
Aire drives steroid hormone biosynthesis by medullary thymic epithelial cells	378
The HLA advantage: Why COVID-19 benched you but not your co-worker	334
Antigen-presenting cell activation requires intrinsic and extrinsic STING signaling after the phagocytosis of DNA-damaged cells	331
Single-cell analysis of anti-BCMA CAR T cell therapy in patients with central nervous system autoimmunity	261
Intratumoral immunotherapy relies on B and T cell collaboration	260
RORγt-lineage APCs: The Aire apparent	249
Immunogenomic cancer evolution: A framework to understand cancer immunosuppression	232
Is one lymphocyte’s brake another lymphocyte’s gas?	192
IL-12 regulates type 3 immunity through interfollicular keratinocytes in psoriasiform inflammation	183
Single-cell NAD(H) levels predict clonal lymphocyte expansion dynamics	182
HLA-E–restricted SARS-CoV-2–specific T cells from convalescent COVID-19 patients suppress virus replication despite HLA class Ia down-regulation	179
Silent recognition of flagellins from human gut commensal bacteria by Toll-like receptor 5	174
Operation Nasal Vaccine—Lightning speed to counter COVID-19	174
Genome-wide screening identifies Trim33 as an essential regulator of dendritic cell differentiation	170
Clostridium septicum α-toxin activates the NLRP3 inflammasome by engaging GPI-anchored proteins	169
DPP9 deficiency: An inflammasomopathy that can be rescued by lowering NLRP1/IL-1 signaling	166
Clonally expanded CD38 ^hi cytotoxic CD8 T cells define the T cell infiltrate in checkpoint inhibitor–associated arthritis	161
ILC2s—Bipartisan politicians in cancer	159
Neither naïve nor anergic, “autoimmune” not allergic	158
Antibody-mediated immunity against lung cancer goes retro	151
Group A Streptococcus induces CD1a-autoreactive T cells and promotes psoriatic inflammation	149
Obesity reshapes regulatory T cells in the visceral adipose tissue by disrupting cellular cholesterol homeostasis	149
CD103 fate mapping reveals that intestinal CD103⁻tissue-resident memory T cells are the primary responders to secondary infection	145

Cutaneous innate immune tolerance is mediated by epigenetic control of MAP2K3 by HDAC8/9	137
Gluten induces rapid reprogramming of natural memory αβ and γδ intraepithelial T cells to induce cytotoxicity in celiac disease	137
SARS-CoV-2–specific T cells in unexposed adults display broad trafficking potential and cross-react with commensal antigens	131
CMV, MHC-E, and the quest for an unconventional AIDS vaccine	131
Pulmonary BCG induces lung-resident macrophage activation and confers long-term protection against tuberculosis	131
Epithelial Gasdermin D shapes the host-microbial interface by driving mucus layer formation	127
Maternal gut microbiome–induced IgG regulates neonatal gut microbiome and immunity	127
Single-cell topographical profiling of the immune synapse reveals a biomechanical signature of cytotoxicity	124
CD8 ⁺ T cells specific for conserved coronavirus epitopes correlate with milder disease in patients with COVID-19	120
Class switch toward noninflammatory, spike-specific IgG4 antibodies after repeated SARS-CoV-2 mRNA vaccination	116
Protein kinase R is an innate immune sensor of proteotoxic stress via accumulation of cytoplasmic IL-24	115
DuraBle tolerance to CNS antigens	114
Anti-body antibodies in COVID-19	113
Luck gone cold: A trifecta of B cell mutations associates with cryoglobulinemia	110
Antigen-specific depletion of CD4 ⁺ T cells by CAR T cells reveals distinct roles of higher- and lower-affinity TCRs during autoimmunity	104
GGNBP2 regulates MDA5 sensing triggered by self double-stranded RNA following loss of ADAR1 editing	103
CD5 deletion enhances the antitumor activity of adoptive T cell therapies	100
Staphylococcus aureus skin colonization promotes SLE-like autoimmune inflammation via neutrophil activation and the IL-23/IL-17 axis	99
The m ⁶ A reader IMP2 directs autoimmune inflammation through an IL-17– and TNFα-dependent C/EBP transcription factor axis	97
Single-cell analysis pinpoints distinct populations of cytotoxic CD4 ⁺ T cells and an IL-10 ⁺ CD109 ⁺	97
Subsetting the subsets: Heterogeneity and developmental relationships of T cells in human tumors	96
CD39 ⁺ tissue-resident memory CD8 ⁺ T cells with a clonal overlap across compartments mediate antitumor immunity in breast cancer	95
A particulate saponin/TLR agonist vaccine adjuvant alters lymph flow and modulates adaptive immunity	93
RNA exosome drives early B cell development via noncoding RNA processing mechanisms	90
Erratum for the Research Article “TGF-β specifies T _FH versus T _H 17 cell fates in murine CD4 ⁺	87
Potent TRIM21 and complement-dependent intracellular antiviral immunity requires the IgG3 hinge	86
Microbial energy metabolism fuels an intestinal macrophage niche in solitary isolated lymphoid tissues through purinergic signaling	85
Dynamic STING repression orchestrates immune cell development and function	83
Sustained CD28 costimulation is required for self-renewal and differentiation of TCF-1 ⁺ PD-1 ⁺ CD8 T cells	82
Immune determinants of chronic sequelae after respiratory viral infection	80
The AIM2 and NLRP3 inflammasomes trigger IL-1–mediated antitumor effects during radiation	80
SLAMF7 engagement superactivates macrophages in acute and chronic inflammation	77
Loss-of-function mutation in IKZF2 leads to immunodeficiency with dysregulated germinal center reactions and reduction of MAIT cells	76
The palmitoylation of gasdermin D directs its membrane translocation and pore formation during pyroptosis	75
SARS-CoV-2 Omicron-neutralizing memory B cells are elicited by two doses of BNT162b2 mRNA vaccine	75
Androgen conspires with the CD8 ⁺ T cell exhaustion program and contributes to sex bias in cancer	72
BCL6 is required for the thymic development of TCRαβ ⁺ CD8αα ⁺ intraepithelial lymphocyte lineage	71
Androgen effects cause sex-biased impairment of CD8 ⁺ T cell antitumor activity	71
Unearthing the Rosetta Stone of public antibody responses	70
IL-17–dependent fibroblastic reticular cell training boosts tissue protective mucosal immunity through IL-10–producing B cells	68
Dysregulation of γδ intraepithelial lymphocytes precedes Crohn’s disease–like ileitis	67
Tissue-specific nonheritable influences drive endometrial immune system variation	67
CAR keys to unlock the intracellular immunopeptidome	67
Microbial uptake in oral mucosa–draining lymph nodes leads to rapid release of cytotoxic CD8 ⁺ T cells lacking a gut-homing phenotype	67