Science Immunology

Papers
(The H4-Index of Science Immunology is 68. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)
ArticleCitations
The HLA advantage: Why COVID-19 benched you but not your co-worker420
CLNS1A regulates genome stability and cell cycle progression to control CD4 T cell function and autoimmunity393
Is one lymphocyte’s brake another lymphocyte’s gas?308
RORγt-lineage APCs: The Aire apparent286
Antigen-presenting cell activation requires intrinsic and extrinsic STING signaling after the phagocytosis of DNA-damaged cells261
Characterization of the mammalian prodefinitive angio-hematopoietic lineage235
T cell help induces Myc transcriptional bursts in germinal center B cells during positive selection220
Hypoxia-induced EGR1 remodels neutrophils to suppress antitumor immunity214
HLA-E–restricted SARS-CoV-2–specific T cells from convalescent COVID-19 patients suppress virus replication despite HLA class Ia down-regulation211
Genome-wide screening identifies Trim33 as an essential regulator of dendritic cell differentiation196
Immunogenomic cancer evolution: A framework to understand cancer immunosuppression194
Intratumoral immunotherapy relies on B and T cell collaboration185
Clostridium septicum α-toxin activates the NLRP3 inflammasome by engaging GPI-anchored proteins170
Waking the sleeping giant: Single-stranded DNA binds Schlafen 11 to initiate innate immune responses169
Single-cell NAD(H) levels predict clonal lymphocyte expansion dynamics165
Operation Nasal Vaccine—Lightning speed to counter COVID-19157
DPP9 deficiency: An inflammasomopathy that can be rescued by lowering NLRP1/IL-1 signaling133
Single-cell analysis of anti-BCMA CAR T cell therapy in patients with central nervous system autoimmunity129
Silent recognition of flagellins from human gut commensal bacteria by Toll-like receptor 5127
Aire drives steroid hormone biosynthesis by medullary thymic epithelial cells127
Clonally expanded CD38 hi cytotoxic CD8 T cells define the T cell infiltrate in checkpoint inhibitor–associated arthritis127
Neither naïve nor anergic, “autoimmune” not allergic125
ILC2s—Bipartisan politicians in cancer125
Antibody-mediated immunity against lung cancer goes retro124
Allergen-induced airway matrix remodeling in mice can be prevented or reversed by targeting chitinase-like proteins124
Simultaneous priming of HIV broadly neutralizing antibody precursors to multiple epitopes by germline-targeting mRNA-LNP immunogens in mouse models121
Group A Streptococcus induces CD1a-autoreactive T cells and promotes psoriatic inflammation121
Single-cell topographical profiling of the immune synapse reveals a biomechanical signature of cytotoxicity115
Obesity reshapes regulatory T cells in the visceral adipose tissue by disrupting cellular cholesterol homeostasis113
Gluten induces rapid reprogramming of natural memory αβ and γδ intraepithelial T cells to induce cytotoxicity in celiac disease107
Epithelial Gasdermin D shapes the host-microbial interface by driving mucus layer formation101
Chimeric autoantibody receptor T cells clonally eliminate B cells producing autoantibodies against IFN-γ100
Maternal gut microbiome–induced IgG regulates neonatal gut microbiome and immunity100
Protein kinase R is an innate immune sensor of proteotoxic stress via accumulation of cytoplasmic IL-2498
SARS-CoV-2–specific T cells in unexposed adults display broad trafficking potential and cross-react with commensal antigens97
CD103 fate mapping reveals that intestinal CD103tissue-resident memory T cells are the primary responders to secondary infection97
Class switch toward noninflammatory, spike-specific IgG4 antibodies after repeated SARS-CoV-2 mRNA vaccination95
Luck gone cold: A trifecta of B cell mutations associates with cryoglobulinemia94
Erratum for the Research Article “TGF-β specifies T FH versus T H 17 cell fates in murine CD4 + 93
SARS-CoV-2 Omicron-neutralizing memory B cells are elicited by two doses of BNT162b2 mRNA vaccine93
Immune determinants of chronic sequelae after respiratory viral infection92
BCL6 is required for the thymic development of TCRαβ + CD8αα + intraepithelial lymphocyte lineage91
Tissue origin and virus specificity shape human CD8 + T cell cytotoxicity86
Dissection of the immune landscape in psoriatic arthritis defines immunoproteasome up-regulation in treatment resistance86
Potent TRIM21 and complement-dependent intracellular antiviral immunity requires the IgG3 hinge86
Microbial energy metabolism fuels an intestinal macrophage niche in solitary isolated lymphoid tissues through purinergic signaling85
Dynamic STING repression orchestrates immune cell development and function84
Maternal allergy and neonatal RSV infection synergize via FcR-mediated allergen uptake to promote the development of asthma in early life84
Staphylococcus aureus skin colonization promotes SLE-like autoimmune inflammation via neutrophil activation and the IL-23/IL-17 axis83
Antigen-specific depletion of CD4 + T cells by CAR T cells reveals distinct roles of higher- and lower-affinity TCRs during autoimmunity82
Sustained CD28 costimulation is required for self-renewal and differentiation of TCF-1 + PD-1 + CD8 T cells82
The palmitoylation of gasdermin D directs its membrane translocation and pore formation during pyroptosis81
GGNBP2 regulates MDA5 sensing triggered by self double-stranded RNA following loss of ADAR1 editing78
CD39 + tissue-resident memory CD8 + T cells with a clonal overlap across compartments mediate antitumor immunity in breast cancer77
RNA exosome drives early B cell development via noncoding RNA processing mechanisms77
CD5 deletion enhances the antitumor activity of adoptive T cell therapies74
SLAMF7 engagement superactivates macrophages in acute and chronic inflammation74
Androgen conspires with the CD8 + T cell exhaustion program and contributes to sex bias in cancer74
Unearthing the Rosetta Stone of public antibody responses72
Gutsy memory T cells stand their ground against pathogens72
Androgen effects cause sex-biased impairment of CD8 + T cell antitumor activity72
CAR keys to unlock the intracellular immunopeptidome72
Group 2 innate lymphoid cells regulate nociceptive and gait functions of the peripheral nervous system71
Antigen cross-presentation in young tumor-bearing hosts promotes CD8 + T cell terminal differentiation71
Tissue-specific nonheritable influences drive endometrial immune system variation70
Multimodal delineation of a layer of effector function among exhausted CD8 T cells in tumors70
Mucosal and systemic immune correlates of viral control after SARS-CoV-2 infection challenge in seronegative adults70
IgE plasma cells are transcriptionally and functionally distinct from other isotypes69
Neutrophils and macrophages drive TNF-induced lethality via TRIF/CD14-mediated responses68
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