Science Immunology

Papers
(The H4-Index of Science Immunology is 69. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)
ArticleCitations
The HLA advantage: Why COVID-19 benched you but not your co-worker337
Is one lymphocyte’s brake another lymphocyte’s gas?316
Waking the sleeping giant: Single-stranded DNA binds Schlafen 11 to initiate innate immune responses285
The OAS–RNase L pathway: Insights from experiments of nature277
Hypoxia-induced EGR1 remodels neutrophils to suppress antitumor immunity241
RORγt-lineage APCs: The Aire apparent202
Characterization of the mammalian prodefinitive angio-hematopoietic lineage202
DNA-damaging chemotherapy reshapes cardiac-resident macrophage composition and function195
CLNS1A regulates genome stability and cell cycle progression to control CD4 T cell function and autoimmunity192
Single-cell NAD(H) levels predict clonal lymphocyte expansion dynamics159
Aire drives steroid hormone biosynthesis by medullary thymic epithelial cells155
HLA-E–restricted SARS-CoV-2–specific T cells from convalescent COVID-19 patients suppress virus replication despite HLA class Ia down-regulation149
Operation Nasal Vaccine—Lightning speed to counter COVID-19149
Genome-wide screening identifies Trim33 as an essential regulator of dendritic cell differentiation148
T cell help induces Myc transcriptional bursts in germinal center B cells during positive selection147
Single-cell analysis of anti-BCMA CAR T cell therapy in patients with central nervous system autoimmunity136
DPP9 deficiency: An inflammasomopathy that can be rescued by lowering NLRP1/IL-1 signaling134
Clonally expanded CD38 hi cytotoxic CD8 T cells define the T cell infiltrate in checkpoint inhibitor–associated arthritis130
Silent recognition of flagellins from human gut commensal bacteria by Toll-like receptor 5130
Immunogenomic cancer evolution: A framework to understand cancer immunosuppression125
Structural variation tunes apoptotic responses to drive immune escape in melanoma118
Antigen-presenting cell activation requires intrinsic and extrinsic STING signaling after the phagocytosis of DNA-damaged cells116
Neither naïve nor anergic, “autoimmune” not allergic115
Antibody-mediated immunity against lung cancer goes retro114
The rise of spatial TCR profiling: Emerging technologies and open challenges113
Allergen-induced airway matrix remodeling in mice can be prevented or reversed by targeting chitinase-like proteins112
ILC2s—Bipartisan politicians in cancer109
CD103 fate mapping reveals that intestinal CD103tissue-resident memory T cells are the primary responders to secondary infection107
Group A Streptococcus induces CD1a-autoreactive T cells and promotes psoriatic inflammation104
SARS-CoV-2–specific T cells in unexposed adults display broad trafficking potential and cross-react with commensal antigens103
Maternal gut microbiome–induced IgG regulates neonatal gut microbiome and immunity101
Chimeric autoantibody receptor T cells clonally eliminate B cells producing autoantibodies against IFN-γ97
Single-cell topographical profiling of the immune synapse reveals a biomechanical signature of cytotoxicity97
Class switch toward noninflammatory, spike-specific IgG4 antibodies after repeated SARS-CoV-2 mRNA vaccination96
Simultaneous priming of HIV broadly neutralizing antibody precursors to multiple epitopes by germline-targeting mRNA-LNP immunogens in mouse models95
Gluten induces rapid reprogramming of natural memory αβ and γδ intraepithelial T cells to induce cytotoxicity in celiac disease94
Obesity reshapes regulatory T cells in the visceral adipose tissue by disrupting cellular cholesterol homeostasis93
Luck gone cold: A trifecta of B cell mutations associates with cryoglobulinemia91
Erratum for the Research Article “TGF-β specifies T FH versus T H 17 cell fates in murine CD4 90
BCL6 is required for the thymic development of TCRαβ + CD8αα + intraepithelial lymphocyte lineage87
GGNBP2 regulates MDA5 sensing triggered by self double-stranded RNA following loss of ADAR1 editing86
Immune determinants of chronic sequelae after respiratory viral infection85
CD5 deletion enhances the antitumor activity of adoptive T cell therapies84
Tissue origin and virus specificity shape human CD8 + T cell cytotoxicity83
Dynamic STING repression orchestrates immune cell development and function83
Dissection of the immune landscape in psoriatic arthritis defines immunoproteasome up-regulation in treatment resistance82
Sustained CD28 costimulation is required for self-renewal and differentiation of TCF-1 + PD-1 + CD8 T cells81
Staphylococcus aureus skin colonization promotes SLE-like autoimmune inflammation via neutrophil activation and the IL-23/IL-17 axis81
Epidermal growth factor receptor controls sex differences in lung type 2 responses to inhaled allergen80
Maternal allergy and neonatal RSV infection synergize via FcR-mediated allergen uptake to promote the development of asthma in early life80
B cells gone broad: A deep dive into SARS-CoV-2 antibody breadth78
Microbial energy metabolism fuels an intestinal macrophage niche in solitary isolated lymphoid tissues through purinergic signaling78
Antigen-specific depletion of CD4 + T cells by CAR T cells reveals distinct roles of higher- and lower-affinity TCRs during autoimmunity78
RNA exosome drives early B cell development via noncoding RNA processing mechanisms77
CD39 + tissue-resident memory CD8 + T cells with a clonal overlap across compartments mediate antitumor immunity in breast cancer77
The palmitoylation of gasdermin D directs its membrane translocation and pore formation during pyroptosis76
Androgen conspires with the CD8 + T cell exhaustion program and contributes to sex bias in cancer75
Gutsy memory T cells stand their ground against pathogens75
Androgen effects cause sex-biased impairment of CD8 + T cell antitumor activity74
Non-apoptotic FAS signaling controls mTOR activation and extrafollicular maturation in human B cells73
Dysregulation of γδ intraepithelial lymphocytes precedes Crohn’s disease–like ileitis73
Intratumoral T reg cell ablation elicits NK cell–mediated control of CD8 T cell–resistant tumors73
Unearthing the Rosetta Stone of public antibody responses73
IgE plasma cells are transcriptionally and functionally distinct from other isotypes73
Exposure to BA.4/5 S protein drives neutralization of Omicron BA.1, BA.2, BA.2.12.1, and BA.4/5 in vaccine-experienced humans and mice72
Microbial uptake in oral mucosa–draining lymph nodes leads to rapid release of cytotoxic CD8 + T cells lacking a gut-homing phenotype72
Myeloid OTULIN deficiency couples RIPK3-dependent cell death to Nlrp3 inflammasome activation and IL-1β secretion71
SARS-CoV-2 spike conformation determines plasma neutralizing activity elicited by a wide panel of human vaccines71
Tissue-specific nonheritable influences drive endometrial immune system variation70
Mucosal and systemic immune correlates of viral control after SARS-CoV-2 infection challenge in seronegative adults69
NKG2D-mediated detection of metabolically stressed hepatocytes by innate-like T cells is essential for initiation of NASH and fibrosis69
Group 2 innate lymphoid cells regulate nociceptive and gait functions of the peripheral nervous system69
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