OOIR: Observatory of International Research

Papers

(The H4-Index of Science Immunology is 77. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-10-01 to 2024-10-01.)

Article	Citations
Persistence of serum and saliva antibody responses to SARS-CoV-2 spike antigens in COVID-19 patients	659
Distinct antibody and memory B cell responses in SARS-CoV-2 naïve and recovered individuals after mRNA vaccination	545
Persistence and decay of human antibody responses to the receptor binding domain of SARS-CoV-2 spike protein in COVID-19 patients	518
SARS-CoV-2 variants of concern partially escape humoral but not T cell responses in COVID-19 convalescent donors and vaccine recipients	471
Defining the features and duration of antibody responses to SARS-CoV-2 infection associated with disease severity and outcome	397
Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths	392
Divergent SARS-CoV-2 Omicron–reactive T and B cell responses in COVID-19 vaccine recipients	359
X-linked recessive TLR7 deficiency in ~1% of men under 60 years old with life-threatening COVID-19	291
Rapid generation of durable B cell memory to SARS-CoV-2 spike and nucleocapsid proteins in COVID-19 and convalescence	246
Vaccination before or after SARS-CoV-2 infection leads to robust humoral response and antibodies that effectively neutralize variants	244
Three tissue resident macrophage subsets coexist across organs with conserved origins and life cycles	239
Impaired humoral immunity to SARS-CoV-2 BNT162b2 vaccine in kidney transplant recipients and dialysis patients	236
Respiratory mucosal immunity against SARS-CoV-2 after mRNA vaccination	206
SARS-CoV-2 genome-wide T cell epitope mapping reveals immunodominance and substantial CD8 ⁺ T cell activation in COVID-19 patients	189
Severely ill patients with COVID-19 display impaired exhaustion features in SARS-CoV-2–reactive CD8 ⁺ T cells	188
Inflammatory profiles across the spectrum of disease reveal a distinct role for GM-CSF in severe COVID-19	175
A reservoir of stem-like CD8 ⁺ T cells in the tumor-draining lymph node preserves the ongoing antitumor immune response	175
BNT162b2 vaccination induces durable SARS-CoV-2–specific T cells with a stem cell memory phenotype	173
Single-cell analysis of human B cell maturation predicts how antibody class switching shapes selection dynamics	172
Regulatory T cell control of systemic immunity and immunotherapy response in liver metastasis	172
Prolonged evolution of the human B cell response to SARS-CoV-2 infection	166
Discordant neutralizing antibody and T cell responses in asymptomatic and mild SARS-CoV-2 infection	164
SARS-CoV-2 infection generates tissue-localized immunological memory in humans	163
Omicron BA.1 breakthrough infection drives cross-variant neutralization and memory B cell formation against conserved epitopes	160
Increased complement activation is a distinctive feature of severe SARS-CoV-2 infection	154

SARS-CoV-2 drives JAK1/2-dependent local complement hyperactivation	150
Gut microbiota–specific IgA ⁺ B cells traffic to the CNS in active multiple sclerosis	147
Deep immune profiling of MIS-C demonstrates marked but transient immune activation compared with adult and pediatric COVID-19	145
Pharmacological activation of STING blocks SARS-CoV-2 infection	145
SARS-CoV-2 mutations in MHC-I-restricted epitopes evade CD8 ⁺ T cell responses	140
NLRP3 inflammasome activation triggers gasdermin D–independent inflammation	140
Clonal expansion and activation of tissue-resident memory-like T _H 17 cells expressing GM-CSF in the lungs of patients with severe COVID-19	137
Tissue-resident CD4 ⁺ T helper cells assist the development of protective respiratory B and CD8 ⁺ T cell memory responses	135
Adaptive immune determinants of viral clearance and protection in mouse models of SARS-CoV-2	135
Multiplexed imaging mass cytometry of the chemokine milieus in melanoma characterizes features of the response to immunotherapy	133
The known unknowns of T cell immunity to COVID-19	128
Integrated longitudinal immunophenotypic, transcriptional, and repertoire analyses delineate immune responses in patients with COVID-19	128
Human dendritic cells in cancer	126
Innate immunological pathways in COVID-19 pathogenesis	125
CD8 ⁺ T cells specific for conserved coronavirus epitopes correlate with milder disease in patients with COVID-19	125
A cross-talk between CAR T cell subsets and the tumor microenvironment is essential for sustained cytotoxic activity	124
ZBP1-dependent inflammatory cell death, PANoptosis, and cytokine storm disrupt IFN therapeutic efficacy during coronavirus infection	122
Class switch toward noninflammatory, spike-specific IgG4 antibodies after repeated SARS-CoV-2 mRNA vaccination	122
The microbiome-derived metabolite TMAO drives immune activation and boosts responses to immune checkpoint blockade in pancreatic cancer	117
Tumor-draining lymph nodes: At the crossroads of metastasis and immunity	117
Bispecific antibodies targeting mutantRASneoantigens	117
Immune signatures underlying post-acute COVID-19 lung sequelae	116
A diamidobenzimidazole STING agonist protects against SARS-CoV-2 infection	115
Polyclonal expansion of TCR Vβ 21.3⁺CD4⁺and CD8⁺T cells is a hallmark of multisystem inflammatory syndrome in children	111
Contribution of resident and circulating precursors to tumor-infiltrating CD8 ⁺ T cell populations in lung cancer	110
T cell factor 1: A master regulator of the T cell response in disease	107
Human airway mast cells proliferate and acquire distinct inflammation-driven phenotypes during type 2 inflammation	101
Antigenic cartography of SARS-CoV-2 reveals that Omicron BA.1 and BA.2 are antigenically distinct	100
CXCL9 and CXCL10 bring the heat to tumors	100
Androgen conspires with the CD8 ⁺ T cell exhaustion program and contributes to sex bias in cancer	99
T resident helper cells promote humoral responses in the lung	97
Transforming growth factor–β1 in regulatory T cell biology	96
The expansion of human T-bet ^high CD21 ^low B cells is T cell dependent	96
Intranasal priming induces local lung-resident B cell populations that secrete protective mucosal antiviral IgA	95
Understanding T cell responses to COVID-19 is essential for informing public health strategies	95
Recall of preexisting cross-reactive B cell memory after Omicron BA.1 breakthrough infection	94
Microglial autophagy–associated phagocytosis is essential for recovery from neuroinflammation	94
Persistence of mature dendritic cells, T _H 2A, and Tc2 cells characterize clinically resolved atopic dermatitis under IL-4Rα blockade	93
Sequence of αPD-1 relative to local tumor irradiation determines the induction of abscopal antitumor immune responses	92
SARS-CoV-2 Omicron-neutralizing memory B cells are elicited by two doses of BNT162b2 mRNA vaccine	91
Itaconate controls the severity of pulmonary fibrosis	91
COVID-19 vaccine side effects: The positives about feeling bad	91
CD8 T cells contribute to vaccine protection against SARS-CoV-2 in macaques	91
PD-1 blockade exacerbates Mycobacterium tuberculosis infection in rhesus macaques	85
Tissue-resident CD8 ⁺ T cells drive age-associated chronic lung sequelae after viral pneumonia	84
The circadian immune system	83
Cellular context of IL-33 expression dictates impact on anti-helminth immunity	83
A particulate saponin/TLR agonist vaccine adjuvant alters lymph flow and modulates adaptive immunity	82
Coral gasdermin triggers pyroptosis	82
Identification of a broadly fibrogenic macrophage subset induced by type 3 inflammation	79

Lack of CD8 ⁺ T cell effector differentiation during priming mediates checkpoint blockade resistance in non–small cell lung cancer	77
NF-κB–dependent IRF1 activation programs cDC1 dendritic cells to drive antitumor immunity	77