Epilepsia Open

Papers
(The median citation count of Epilepsia Open is 1. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-02-01 to 2025-02-01.)
ArticleCitations
Microglia and status epilepticus in the immature brain60
Neuropsychiatric profile in average intelligent individuals with coexisting epilepsy and psychogenic non‐epileptic seizures49
Characterization of low‐grade epilepsy‐associated tumor from implanted stereoelectroencephalography electrodes48
Implantation/explantation of sEEG electrodes and takotsubo syndrome: Plausible merits of some additions to the protocol40
A companion to the preclinical common data elements for genomics, transcriptomics, and epigenomics data in rodent epilepsy models. A report of the TASK3‐WG4 omics working group of the 33
The hidden link between late‐onset seizures and cerebral amyloid angiopathy: A case–control study33
Memory compromise at extended delays in people with new‐onset epilepsy28
Navigating Dravet syndrome in Spain: A cross‐sectional study of diagnosis, management, and care coordination28
Clinical and genetic analysis of 23 Chinese children with epilepsy associated with KCNQ2 gene mutations27
Ictal and interictalSPECTwith99mTc‐HMPAOin presurgical epilepsy. I: Predictive value and methodological considerations22
Key steps and barriers in the journey of patients with epilepsy through the National Healthcare System in Spain: The EPIPASS qualitative study22
An interview with Nadia Adotevi, 2023 Epilepsia Open Prize winner for basic science20
An interview with Ifrah Zawar, 2023 Epilepsia Open prize winner for clinical research20
Decreased serum concentrations of antiseizure medications in children with drug resistant epilepsy following treatment with ketogenic diet19
Issue Information17
Programmed mechanisms of status epilepticus‐induced neuronal necrosis17
Ettore Beghi (1947–2022): A farewell17
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Insulo‐opercular stereoelectroencephalography exploration in children and young adults: Indications, techniques, and safety16
High FGF‐21 level in a cohort of 22 patients with Dravet Syndrome—Possible relationship with the disease outcomes15
Electroclinical features and phenotypic differences in adenylosuccinate lyase deficiency: Long‐term follow‐up of seven patients from four families and appraisal of the literature14
E = mc2: Education (E), medication (m), and conditional cash (c2) to improve uptake of antiseizure medications in a low‐resource pop14
Parsing neuronal circuits involved in comorbidities of epilepsy: A commentary on “Focal impaired awareness seizures in a rodent model: A functional anatomy”14
Phosphatidylserine enriched with polyunsaturated n‐3 fatty acid supplementation for attention‐deficit hyperactivity disorder in children and adolescents with epilepsy: A randomized p14
A 5‐year‐old boy with super‐refractory status epilepticus and RANBP2 variant warranting life‐saving hemispherotomy13
Survey of an online system for information to women with epilepsy of childbearing age and management during pregnancy: A 3‐year evaluation13
Status epilepticus in BRAF‐related cardio‐facio‐cutaneous syndrome: Focus on neuroimaging clues to physiopathology13
Readability and content gaps in online epilepsy surgery materials as potential health literacy and shared‐decision‐making barriers13
Efficacy and safety of a smartphone application‐based treatment of ketogenic diet in pediatric refractory epilepsy13
Epilepsies with onset during the first year of life: A prospective study on syndromes, etiologies, and outcomes12
Myoclonus: Differential diagnosis and current management12
Risk of COVID‐19 infection and seizure exacerbation among patients with epilepsy during the peak of Omicron wave12
Tolerance, adherence, and acceptability of a ketogenic 2.5:1 ratio, nutritionally complete, medium chain triglyceride‐containing liquid feed in children and adults with drug‐resistant epilepsy followi12
The mechanism of mitochondrial autophagy regulating Clathrin‐mediated endocytosis in epilepsy12
Characterization of alcohol‐related seizures in withdrawal syndrome12
Epilepsy and neurocysticercosis in rural areas of the Bolivian Chaco: What has changed during the last 30 years?12
Development of a novel dosing paradigm to model diazepam rescue therapy in preclinical seizure and epilepsy models11
Alterations of apparent diffusion coefficient from ultra high b‐values in the bilateral thalamus and striatum in MRI‐negative drug‐resistant epilepsy11
Prospective study of epilepsy with generalized tonic–clonic seizures alone: Clinical features, response to treatment, and likelihood of medication withdrawal11
Hospital‐acquired infections as a risk factor for post‐traumatic epilepsy: A registry‐based cohort study11
Cardiovascular risk factor assessment in late‐onset seizures: A study protocol to assess the value of structured intervention10
Epilepsia Open—June 2024 Announcements10
Long‐term outcomes after NORSE: Treatment with vagus nerve stimulation10
Response: Letter to FKBP5 blockade may provide a new horizon for the treatment of stress‐associated disorders: An in silico study10
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Issue Information10
Epilepsia Open – September 2021 – Announcements10
Scalp high‐frequency oscillations differentiate neonates with seizures from healthy neonates10
Commentary on “The epileptogenic zone in children with tuberous sclerosis complex is characterized by prominent features of focal cortical dysplasia”10
Issue Information10
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Thank you to our Reviewers of 202010
Experimental status epilepticus, COX‐2 and BDNF: Connecting the dots9
Parvalbumin neurons in the anterior nucleus of thalamus control absence seizures9
3D figure of epilepsy syndromes9
Association of patent foramen ovale with epilepsy: A hospital‐based case–control study9
Remote effects of temporal lobe epilepsy surgery: Long‐term morphological changes after surgical resection9
An epidemiological survey of epilepsy in tropical rural areas of China9
Medical treatment in infants and young children with epilepsy: Off‐label use of antiseizure medications. Survey Report of ILAE Task Force Medical Therapies in Children9
Availability, affordability, and quality of essential anti‐seizure medication in Cambodia9
Epilepsy in Niger: An overview of the current situation9
Astrocyte reactivity in a mouse model of SCN8A epileptic encephalopathy9
The origins and early development of the ILAE/IBE/WHO global campaign against epilepsy: Out of the shadows9
Long‐term effectiveness and tolerability of ketogenic diet therapy in patients with genetic developmental and epileptic encephalopathy onset within the first 6 months of life9
Feasibility, tolerability and efficacy of the ketogenic diet in children with drug‐resistant epilepsy in Vietnam9
Ceribell EEG shortens seizure diagnosis and workforce time and is useful for COVID isolation9
Prevalence of epilepsy in Morocco: A population‐based study9
Comparative efficacy and safety of stiripentol, cannabidiol and fenfluramine as first‐line add‐on therapies for seizures in Dravet syndrome: A network meta‐analysis8
Causal relationship between telomere length and epilepsy: A bidirectional Mendelian randomization study8
Drugs acting at TRPM7 channels inhibit seizure‐like activity8
The long‐term surgical outcomes of low‐grade epilepsy‐associated neuroepithelial tumors8
Longitudinal hippocampal diffusion‐weighted imaging and T2 relaxometry demonstrate regional abnormalities which are stable and predict subfield pathology in temporal lobe epilepsy8
Real‐world antiseizure medication treatment outcomes in drug‐resistant focal epilepsy patients8
Evaluation of the International League Against Epilepsy 1981, 1989, and 2017 classifications of seizure semiology and etiology in a population‐based cohort of children and adults with epilepsy8
Implantation and reimplantation of intracranial EEG electrodes in patients considering epilepsy surgery8
Temporal encephaloceles and coexisting epileptogenic lesions8
Effect of transcutaneous vagus nerve stimulation on stress‐reactive neuroendocrine measures in a sample of persons with temporal lobe epilepsy8
Safety and effectiveness of diazepam nasal spray in male and female patients: Post hoc analysis of data from a phase 3 safety study8
Influence of extent and age at corpus callosotomy on seizure outcomes. A single center experience8
Pregabalin as adjunctive therapy in adult and pediatric patients with generalized tonic‐clonic seizures: A randomized, placebo‐controlled trial8
The causal effect of serum 25‐hydroxyvitamin D levels on epilepsy: A two‐sample Mendelian randomization study8
FDA safety warning on the cardiac effects of lamotrigine: An advisory from the Ad Hoc ILAE/AES Task Force7
Variation in seizure risk increases from antiseizure medication withdrawal among patients with well‐controlled epilepsy: A pooled analysis7
Ordinal regression increases statistical power to predict epilepsy surgical outcomes7
Sevoflurane as bridge therapy for plasma exchange and Anakinra in febrile infection–related epilepsy syndrome7
Addressing neuropsychological diagnostics in adults with epilepsy: Introducing the International Classification of Cognitive Disorders in Epilepsy: The IC CODE Initiative7
Effectiveness of perampanel as the only add‐on: Retrospective, multicenter, observational real‐life study on epilepsy patients7
Real‐world data on cannabidiol treatment of various epilepsy subtypes: A retrospective, multicenter study7
Multi‐omic strategies applied to the study of pharmacoresistance in mesial temporal lobe epilepsy7
Impact of COVID‐19 pandemic on epilepsy care in Japan: A national‐level multicenter retrospective cohort study7
Vaccination against COVID‐19 and potential protective effects on seizure recurrence in children with epilepsy: A cross‐sectional survey7
Comorbid seizure reduction after pallidothalamic tractotomy for movement disorders: Revival of Jinnai’s Forel‐H‐tomy7
Seizures in Sotos syndrome: Phenotyping in 49 patients7
Report of the ILAE SUDEP Task Force on national recommendations and practices around the world regarding the use of wearable seizure detection devices: A global survey7
Epilepsy care pathway: The Finnish model7
A companion to the preclinical common data elements for proteomics, lipidomics, and metabolomics data in rodent epilepsy models. A report of the TASK3‐WG4 omics working group of the ILAE/AES joint tra7
Seizure‐related injuries in people with epilepsy: A cohort study from Saudi Arabia7
Management and outcomes among older adults with generalized epilepsy in routine clinical practice7
Subjective cognition is linked to everyday functioning in epilepsy7
Rapid response electroencephalography decreases time to seizure diagnosis in pediatric acute care patients6
Clinical characteristics and outcomes after new‐onset seizure among Zambian children with HIV during the antiretroviral therapy era6
Assessment of tau phosphorylation and β‐amyloid pathology in human drug‐resistant epilepsy6
WRAPPER study: Real‐world effectiveness and tolerability of adjunctive perampanel for people with drug–resistant epilepsy in Hong Kong6
Surgical management of status epilepticus: A systematic review6
A companion to the preclinical common data elements for rodent genetic epilepsy models. A report of the TASK3‐WG1B: Paediatric and genetic models working group of the ILAE/A6
Development and validation of a peripheral cell ratio and lactate score for differentiating status epilepticus from prolonged psychogenic nonepileptic seizures6
Factors not considered in the study of drug‐resistant epilepsy: Drug‐resistant epilepsy: Assessment of neuroinflammation6
A cross‐sectional study of COVID‐19 vaccination patterns among patients with epilepsy in Hong Kong6
Characteristics of deceased subjects transported to a postmortem imaging center due to unusual death related to epilepsy6
Patient complexity, depression, and quality of life in patients with epilepsy at an epilepsy center in Japan6
EEG datasets for seizure detection and prediction— A review6
Identification and clinical characteristics of a novel missense ADGRG1 variant in bilateral Frontoparietal Polymicrogyria: The electroclinical change from infancy to adulthood after Calloso6
Type 2 diabetes mellitus facilitates status epilepticus in adult rats: Seizure severity, neurodegeneration, and oxidative stress6
Drug‐resistant epilepsy: Drug target hypothesis and beyond the receptors6
The efficacy and safety of ganaxolone for the treatment of refractory epilepsy: A meta‐analysis from randomized controlled trials6
Experience with the ketogenic diet in premature neonates6
The clinical analysis of new‐onset status epilepticus6
Deep‐learning predicted PET can be subtracted from the true clinical fluorodeoxyglucose PET co‐registered to MRI to identify the epileptogenic zone in focal epilepsy6
Biodegradable nanoparticles for the treatment of epilepsy: From current advances to future challenges6
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The causal relationship of DTI phenotypes and epilepsy: A two sample mendelian randomization study5
Lateralization of memory function in temporal lobe epilepsy using scene memory fMRI5
Issue Information5
Outcomes of resective surgery in pediatric patients with drug‐resistant epilepsy: A single‐center study from the Eastern Mediterranean Region5
Association between retinal thickness and disease characteristics in adult epilepsy: A cross‐sectional OCT evaluation5
Integration of interictal EEG source localization in presurgical epilepsy evaluation – A single‐center prospective study5
Erratum: To “the clinical analysis of new‐onset status epilepticus”Deng B, Dai Y, Wang Q, Yang J, Chen X, Liu T–T, et al. The clinical analysis of new‐onset status epilepticus. Epilepsia Open. 2022;7:5
Sleep disturbances in SCN8A‐related disorders5
The impact of ketogenic diet on the frequency of psychogenic non‐epileptic seizures (PNES): A feasibility randomized pilot study5
Leveraging multiple approaches for the detection of pathogenic deep intronic variants in developmental and epileptic encephalopathies: A case report5
Targeted continuous EEG monitoring in critically ill patients: The long and the short of a scalability problem5
The National Comprehensive Governance for epilepsy prevention and control in China5
Anxiety and depression in people with epilepsy during and one year after the COVID‐19 pandemic5
Total posterior quadrant disconnection for drug‐resistant epilepsy in children5
One‐year seizure freedom and quality of life in patients with drug‐resistant epilepsy receiving adjunctive vagus nerve stimulation in Japan5
Therapeutic drug monitoring of perampanel in children diagnosed with epilepsy: Focus on influencing factors on the plasma concentration‐to‐dose ratio5
Left‐sided epileptiform activity influences language lateralization in right mesial temporal sclerosis5
The efficacy and safety of adjunctive perampanel for the treatment of refractory focal‐onset seizures in patients with epilepsy: A meta‐analysis5
Human herpesvirus 6 DNA was not detected in a brain specimen from a patient with mesial temporal sclerosis after status epilepticus due to human herpesvirus 6 infection5
Initial combination versus early sequential standard therapies for Infantile Epileptic Spasms Syndrome—Feedback from stakeholders5
Applying the ILAE diagnostic criteria for Lennox‐Gastaut syndrome in the real‐world setting: A multicenter retrospective cohort study4
Response: Implantation/explantation of sEEG electrodes and takotsubo syndrome: Plausible merits of additions to the protocol4
NORSE seasonality may vary geographically in adults4
A disease concept model for STXBP1‐related disorders4
Assessment of self‐stigma in epilepsy: Validation of the German version Epilepsy Self‐Stigma Scale (ESSS‐G)4
Efficacy and safety of stiripentol in the prevention and cessation of status epilepticus: A systematic review4
Diagnosis and treatment of growth hormone deficiency in children on the ketogenic diet: A case series4
Comparison of magnetic resonance‐guided laser interstitial thermal therapy corpus callosum ablation to open microsurgical corpus callosotomy: A single‐center retrospective cohort study4
Takotsubo stress cardiomyopathy following explantation of sEEG electrodes4
Analyses of seizure responses supportive of a novel trial design to assess efficacy of antiepileptic drugs in infants and young children with epilepsy: Post hoc analyses of pediatric levetiracetam and4
The adaptation of the desirability of outcome ranking for interventional clinical trials in epilepsy: A novel consumer‐led outcome measure4
May anti‐seizure medications alter brain structure in temporal lobe epilepsy? A prospective study4
FKBP5 blockade may provide a new horizon for the treatment of stress‐associated disorders: An in‐silico study4
A multicultural comparative study of self‐stigma in epilepsy: Differences across four cultures4
Sex and gonadectomy modify behavioral seizure susceptibility and mortality in a repeated low‐dose kainic acid systemic injection paradigm in mice4
Bilateral pulvinar responsive neurostimulation for bilateral multifocal posteriorly dominant drug resistant epilepsy4
Efficacy and Safety of adjunctive Perampanel in a prospective, real‐world, Phase IV study in Indian patients aged ≥12 years for Treatment of focal‐onset Epilepsy: Study 5084
An interview with Ying Yu, 2021 EpilepsiaOpen Prize Winner for Basic Science Research4
Performance of ECG‐based seizure detection algorithms strongly depends on training and test conditions4
An approach for reliably identifying high‐frequency oscillations and reducing false‐positive detections4
Sleep architecture in drug‐naïve adult patients with epilepsy: Comparison between focal and generalized epilepsy4
The diagnostic value of ictal SPECT—A retrospective, semiquantitative monocenter study4
Clinical and genetic analysis of infants with pontocerebellar hypoplasia type 6 caused by RARS2 variations4
Cenobamate in refractory epilepsy: Overview of treatment options and practical considerations4
CLN6‐related continuum phenotype caused by aberrant splicing4
Accessibility, availability and common practices regarding genetic testing for epilepsy across Europe: A survey of the European Reference Network EpiCARE4
COVID‐19 response in a long‐term care facility for people with epilepsy4
Prospective multisite cohort study of patient‐reported outcomes in adults with new‐onset seizures3
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Epilepsia Open—June 2022—Announcements3
A companion to the preclinical common data elements and case report forms for neuropathology studies in epilepsy research. A report of the TASK3WG2 Neuropathology Working Group o3
Epidemiology and disease burden of tuberous sclerosis complex in France: A population‐based study based on national health insurance data3
Efficacy of long‐term adrenocorticotropic hormone therapy for West syndrome: A retrospective multicenter case series3
Cardiac structural and functional abnormalities in epilepsy: A systematic review and meta‐analysis3
A cross‐sectional, multicenter survey of the prevalence and influencing factors for migraine in epilepsy3
Antiseizure medication withdrawal risk estimation and recommendations: A survey of American Academy of Neurology and EpiCARE members3
Real‐world analysis of hospitalizations in patients with epilepsy and treated with perampanel3
Risk factors that predict delayed seizure detection on continuous electroencephalogram (cEEG) in a large sample size of critically ill patients3
Thank you to our reviewers of 20233
An international survey of SEEG cortical stimulation practices3
A retrospective, real‐world experience of perampanel monotherapy in patient with first new onset focal seizure: A Thailand experience3
Issue Information3
Epilepsia Open – February 2024 Announcements3
Validation of semi‐automated anatomically labeled SEEG contacts in a brain atlas for mapping connectivity in focal epilepsy3
KETASER01 protocol: What went right and what went wrong3
Spatial and amplitude dynamics of neurostimulation: Insights from the acute intrahippocampal kainate seizure mouse model3
How much time is enough? Establishing an optimal duration of recording for ambulatory video EEG3
Prospective study of cenobamate on cognition, affectivity, and quality of life in focal epilepsy3
Systemic and cerebrospinal fluid immune and complement activation in Ugandan children and adolescents with long‐standing nodding syndrome: A case‐control study3
Prevalence of non‐convulsive seizures and electroencephalographic abnormalities in critically ill patients—A retrospective observational study3
Diversity of kindling of limbic seizures after lateral fluid percussion injury in the rat3
Comparing late‐onset epileptic spasm outcomes after corpus callosotomy and subsequent disconnection surgery between post‐encephalitis/encephalopathy and non‐encephalitis/encephalopathy3
Synchronous heart rate reduction with suppression‐burst pattern in KCNT1‐related developmental and epileptic encephalopathies3
The enigmatic figure of Leon Pierce Clark and his contribution to epilepsy3
Timing differences between HFOs and interictal epileptiform discharges generated in vitro by different mechanisms in rat hippocampal slices: A novel approach3
A European pilot study in Dravet Syndrome to delineate what really matters for the patients and families3
Prevalence of epilepsy in the rural area of the Bolivian Gran Chaco: Usefulness of telemedicine and impact of awareness campaigns3
The goal of explaining black boxes in EEG seizure prediction is not to explain models' decisions3
Frequency of and factors associated with antiseizure medication discontinuation discussions and decisions in patients with epilepsy: A multicenter retrospective chart review3
Creation and implementation of an electronic health record note for quality improvement in pediatric epilepsy: Practical considerations and lessons learned3
ResectVol: A tool to automatically segment and characterize lacunas in brain images3
Interictal magnetic signals in new‐onset Rolandic epilepsy may help with timing of treatment selection3
Leukotriene antagonists reduce epileptic seizures‐related hospitalization in older adult populations with allergic rhinitis or asthma: A population‐based cohort study using the Shizuoka Kokuho databas3
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Glymphatic system dysfunction in temporal lobe epilepsy patients with hippocampal sclerosis2
Response: Extreme delta brush in anti‐NMDAR encephalitis—Mimics and chameleons2
Dynamics of glucose concentration during the initiation of ketogenic diet treatment in children with refractory epilepsy: Results of continuous glucose monitoring2
Causal relationship between oral microbiota and epilepsy risk: Evidence from Mendelian randomization analysis in East Asians2
Brain network entropy, depression, and quality of life in people with traumatic brain injury and seizure disorders2
Eye closure sensitivity as a novel EEG marker of MERRF2
Asymmetric epileptic spasms after corpus callosotomy in children with West syndrome may be a good indicator for unilateral epileptic focus and subsequent resective surgery2
Work productivity, quality of life, and care needs: An unfolding epilepsy burden revealed in the Australian Epilepsy Project pilot study2
Creativity and its link to epilepsy2
Clinical features of unilateral multilobar and hemispheric polymicrogyria (PMG)‐related epilepsy and seizure outcome with different treatment options2
The potential role of astroglial GABAA receptors in autoimmune encephalitis associated with GABAA receptor antibodies and seizures2
Septal stimulation attenuates hippocampal seizure with subregion specificity2
Developmental and epileptic encephalopathy 89: A novel bi‐allelic variant, molecular dynamics simulation, and a comprehensive clinical and molecular profile2
Increased susceptibility to kainate‐induced seizures in a mouse model of tuberous sclerosis complex: Importance of sex and circadian cycle2
Combination of antiseizure medications phenobarbital, ketamine, and midazolam reduces soman‐induced epileptogenesis and brain pathology in rats2
Treatment of status epilepticus: Physiology, pharmacology, and future directions2
Susceptibility to preoperative seizures in glioma patients with elevated homocysteine levels2
Issue Information2
Letter on: 3D figure of epilepsy syndromes2
Italian report on RARE epilepsies (i‐RARE): A consensus on multidisciplinarity2
Robot‐assisted stereoencephalography vs subdural electrodes in the evaluation of temporal lobe epilepsy2
Baseline characteristics and predictors for early implantation of vagus nerve stimulation therapy in people with drug‐resistant epilepsy: Observations from an international prospective outcomes regist2
Analysis of clinical characteristics and histopathological transcription in 40 patients afflicted by epilepsy stemming from focal cortical dysplasia2
Unraveling unmet needs in ketogenic dietary services: An ERN EpiCARE survey2
Multimodal nocturnal seizure detection: Do we need to adapt algorithms for children?2
The significance of multimodality approach in the management of non‐lesional drug‐resistant focal parietal lobe epilepsies2
Epilepsia Open—June 2023—Announcements2
Genetic testing, another important tool in presurgical evaluation of focal epilepsies in childhood2
Introduction to the special issue on status epilepticus: neuronal injury, plasticity, and therapies; Celebrating the legacy of Dr. Claude G. Wasterlain2
Efficacy and safety of perampanel monotherapy in Chinese patients with focal‐onset seizures: A single‐center, prospective, real‐world observational study2
Epilepsy duration is an independent factor for electrocardiographic changes in pediatric epilepsy2
RARS1‐related developmental and epileptic encephalopathy2
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Impact of depressive symptoms on adverse effects in people with epilepsy on antiseizure medication therapy2
Real‐world anti‐seizure treatment and adverse events among individuals living with drug‐resistant focal epilepsy in the United States2
Epileptic spasms relapse is associated with response latency but not conventional attributes of post‐treatment EEG2
The thickness of the retinal nerve fiber layer, macula, and ganglion cell‐inner plexiform layer in people with drug‐resistant epilepsy2
Exploring the impact of hippocampal sclerosis on white matter tracts and memory in individuals with mesial temporal lobe epilepsy2
Broadening the scope of multigene panel analysis for adult epilepsy patients2
Anxiety and depressive symptoms in adults with new‐onset seizures: A scoping review2
Efficacy of anti‐seizure medications and alternative therapies (ketogenic diet, CBD, and quinidine) in KCNT1‐related epilepsy: A systematic review2
In Memoriam: Juhn Atsushi Wada, MD (1924–2023)2
A novel FAME1 repeat configuration in a European family identified using a combined genomics approach2
Efficacy of add‐on Cenobamate treatment in refractory epilepsy due to Rasmussen's encephalitis2
Issue Information2
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