OOIR: Observatory of International Research

Papers

(The TQCC of Current Opinion in Biomedical Engineering is 8. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-12-01 to 2025-12-01.)

Article	Citations
AAV-based CRISPR-Cas9 genome editing: Challenges and engineering opportunities	54
Bioresorbable vascular metallic scaffolds: Current status and research trends	54
Toward the use of muscle reinnveration for chronic bidirectional control of prostheses to improve functional outcomes of end users	49
Editorial Board	49
Using biophysical cues and biomaterials to improve genetic models	47
Brainy biomaterials: Latest advances in smart biomaterials to develop the next generation of neural interfaces	42
Smart orthopedic biomaterials and implants	41
Porous microneedles: Transdermal salt bridge for biomedical device engineering	40
Integrating in vitro disease models of the neurovascular unit into discovery and development of neurotherapeutics	39
The prospect of electroceutical intervention and its implementation toward intractable neuromuscular diseases	39
Defining omics-based biomarker signatures of metabolic dysfunction-associated steatotic liver disease (MASLD): In vitro studies	35
Recent advances in gene therapy for cancer theranostics	33
Developing patient-centric specifications for autologous chimeric antigen receptor T cell therapies	33
Contents	32
Outlook in tissue-engineered magnetic systems and biomagnetic control	31
Emerging trends of discrete Poly(ethylene glycol) in biomedical applications	28
Design of biocompatible and self-antibacterial titanium surfaces for biomedical applications	26
Mining microbial organisms to discover and characterize novel CRISPR-Cas systems	25
Biophysical determinants of nuclear shape and mechanics and their implications for genome integrity	25
AI models for protein design are driving antibody engineering	25
Editorial overview: Scaffold-based and scaffold-free approaches for mechanobiology, in vitro disease modeling and treatment	22
Biomaterial nanocarrier-driven mechanisms to modulate anti-tumor immunity	21
Electrospun biomedical nanofibers and their future as intelligent biomaterials	20
Aging and the extracellular matrix: A tumor-permissive microenvironment driving cancer progression	20
Modular and handheld Raman systems for SERS-based point-of-care diagnostics	20

3M engineering approaches to combat high-shear thrombosis: Integrating modeling, microfluidics, and mechanobiology	18
Multi-omic approaches to acute kidney injury and repair	17
Current trends and definitions in high-performance antimicrobial strategies	17
Contents	17
Intelligent biomaterials for cardiovascular applications	16
Size principles governing selective neuromodulation and recruitment order of nerve fibers	16
Mathematical models of fibrin polymerization: past, present, and future	16
Contents	16
Gut-on-chip and liver-on-chip platforms for pathophysiological modeling	15
Cell therapy products are revolutionizing multiple therapeutic areas; to maintain this pace of innovation, manufacturing solutions must adapt	15
Rigid and soft microelectrodes for electrophysiology measurement	15
Advancing measurement infrastructure for cell and gene therapy product development	15
Generalizable and explainable deep learning for medical image computing: An overview	15
Recent advances in quantifying the mechanobiology of cardiac development via computational modeling	14
Contents	14
Thermogelling materials and their important role in biomedical engineering applications	14
Nano-biomaterials: Emerging tools in biomedical innovation and therapy	14
Errata for editorial disclosures	14
Eye tracking in cardiology	14
Bioelectronic therapies for chronic pain	14
Ultra-high-field MRI studies of brain structure and function in humans and nonhuman primates: A collaborative approach to precision medicine	13
Recent advancements in in vitro models of traumatic brain injury	13
Sustainable electrospun materials with enhanced blood compatibility for wound healing applications—A mini review	12
Smart plasmonic hydrogels based on gold and silver nanoparticles for biosensing application	12
A new function for nuclear lamins: Providing surface tension to the nuclear drop	12
Editorial overview: Current perspectives in bioelectronic medicine: Mechanisms, technologies, and clinical frontiers	11
Antibacterial and antiviral high-performance nanosystems to mitigate new SARS-CoV-2 variants of concern	11
Imaging the microscale mechanical properties of cancer using optical coherence elastography	11
AI-powered wearable sensors for health monitoring and clinical decision making	11
Remote magnetic actuation of cell signalling for tissue engineering	11
Surface modified NiTi smart biomaterials: Surface engineering and biological compatibility	10
Neuromodulation for the treatment of sexual dysfunction: An opportunity for the field	10
Leveraging user preference in the design and evaluation of lower-limb exoskeletons and prostheses	10
Microfluidic platforms for organ-on-a-chip models: Creating dynamic microenvironments for organoid and multi-organ systems	10
Beyond static models: Mechanically dynamic matrices reveal new insights into cancer and fibrosis progression	10
Special issue: Advances in Diagnostic and Theranostic Systems for Disease Treatment	9
Nanomechanics at the extracellular matrix-focal adhesion interface	9
Gelatin-based scaffolds: An intuitive support structure for regenerative therapy	9
What lies beyond—Insights into elastic microscaffolds with metamaterial properties for cell studies	9
Advances in electrospinning of aligned nanofiber scaffolds used for wound dressings	9
Advances in strategies for liver regeneration and replacement	9
Genetically-encoded degraders as versatile modulators of intracellular therapeutic targets	9
Commercial autologous cell therapy: The value of real-time patient and therapy data	9
Editorial Board	9
The role of immune cells in therapeutic angiogenesis: Concepts in tissue engineering	8
Moving to a new dimension: 3D kidney cultures for kidney regeneration	8
The need for tissue-engineered models to facilitate the study of oligodendrocyte progenitor cells in traumatic brain injury and repair	8
Editorial Board	8
The unperturbed picture: Label-free real-time optical monitoring of cells and extracellular vesicles for therapy	8
Recent advances in transdermal sensors for glucose monitoring	8

Perspectives on synthetic protein circuits in mammalian cells	8
Tissue engineering for cervical function in pregnancy	8
Fueling next-generation genome editing with DNA repair	8