JACC-Basic to Translational Science

Papers
(The TQCC of JACC-Basic to Translational Science is 6. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-03-01 to 2024-03-01.)
ArticleCitations
Mechanisms of Cardiovascular Benefits of Sodium Glucose Co-Transporter 2 (SGLT2) Inhibitors392
COVID-19 for the Cardiologist200
Platelet and Endothelial Activation as Potential Mechanisms Behind the Thrombotic Complications of COVID-19 Patients143
SARS-CoV-2 Infects Human Engineered Heart Tissues and Models COVID-19 Myocarditis102
Targeting Vascular Calcification in Chronic Kidney Disease85
The Heart in COVID-1972
Blockade of Fibroblast YAP Attenuates Cardiac Fibrosis and Dysfunction Through MRTF-A Inhibition69
Decentralized Clinical Trials67
Limitations of Animal Studies for Predicting Toxicity in Clinical Trials63
The Integrin Binding Peptide, ATN-161, as a Novel Therapy for SARS-CoV-2 Infection57
The Pathogenesis and Long-Term Consequences of COVID-19 Cardiac Injury54
Mutual Antagonism of Hypoxia-Inducible Factor Isoforms in Cardiac, Vascular, and Renal Disorders53
Targeting the Inflammasome in Cardiovascular Disease52
Iron and Heart Failure52
Intramyocardial Transplantation of Human iPS Cell–Derived Cardiac Spheroids Improves Cardiac Function in Heart Failure Animals48
Postacute Sequelae of Severe Acute Respiratory Syndrome Coronavirus 2 Infection47
Coronary Artery Disease Genetics Enlightened by Genome-Wide Association Studies46
Optimizing Foundational Therapies in Patients With HFrEF44
Genetic and In Vitro Inhibition of PCSK9 and Calcific Aortic Valve Stenosis43
Innate Immune Receptors, Key Actors in Cardiovascular Diseases42
Eosinophil Deficiency Promotes Aberrant Repair and Adverse Remodeling Following Acute Myocardial Infarction42
Relationship of Nonalcoholic Fatty Liver Disease and Heart Failure With Preserved Ejection Fraction41
Dynamic Regulation of SARS-Cov-2 Binding and Cell Entry Mechanisms in Remodeled Human Ventricular Myocardium40
Artificial Intelligence Discusses the Role of Artificial Intelligence in Translational Medicine40
The Role of NLRP3 Inflammasome in Pericarditis39
Autosis38
Treatment Targets for Right Ventricular Dysfunction in Pulmonary Arterial Hypertension37
In Situ Remodeling Overrules Bioinspired Scaffold Architecture of Supramolecular Elastomeric Tissue-Engineered Heart Valves35
Sex-Specific Effects of the Nlrp3 Inflammasome on Atherogenesis in LDL Receptor-Deficient Mice34
Myopathic Cardiac Genotypes Increase Risk for Myocarditis33
Iron Overload via Heme Degradation in the Endoplasmic Reticulum Triggers Ferroptosis in Myocardial Ischemia-Reperfusion Injury31
Nicotinamide Mononucleotide Alleviates Cardiomyopathy Phenotypes Caused by Short-Chain Enoyl-Coa Hydratase 1 Deficiency29
B Cells in Atherosclerosis29
Galectin-3 Inhibition With Modified Citrus Pectin in Hypertension28
TNFR1 Contributes to Activation-Induced Cell Death of Pathological CD4+ T Lymphocytes During Ischemic Heart Failure28
Optogenetic Stimulation of Vagal Efferent Activity Preserves Left Ventricular Function in Experimental Heart Failure27
Antisense Inhibition of Angiotensinogen With IONIS-AGT-LRx26
Cardiorenal Tissues Express SARS-CoV-2 Entry Genes and Basigin (BSG/CD147) Increases With Age in Endothelial Cells26
Selective FPR2 Agonism Promotes a Proresolution Macrophage Phenotype and Improves Cardiac Structure-Function Post Myocardial Infarction25
Novel Göttingen Miniswine Model of Heart Failure With Preserved Ejection Fraction Integrating Multiple Comorbidities24
Erythrocytes Induce Vascular Dysfunction in COVID-1924
Peripheral Determinants of Oxygen Utilization in Heart Failure With Preserved Ejection Fraction24
Cardiac Fibrosis Is Associated With Decreased Circulating Levels of Full-Length CILP in Heart Failure24
Large Animal Models of Heart Failure24
Device-Based Solutions to Improve Cardiac Physiology and Hemodynamics in Heart Failure With Preserved Ejection Fraction23
Proteomic Architecture of Valvular Extracellular Matrix23
Interleukin-1β, Oxidative Stress, and Abnormal Calcium Handling Mediate Diabetic Arrhythmic Risk23
Artificial Intelligence Models Reveal Sex-Specific Gene Expression in Aortic Valve Calcification22
Role of Blood Oxygen Saturation During Post-Natal Human Cardiomyocyte Cell Cycle Activities22
Interplay of Low-Density Lipoprotein Receptors, LRPs, and Lipoproteins in Pulmonary Hypertension22
Micro-RNA Analysis in Pulmonary Arterial Hypertension21
Neprilysin Inhibitors in Heart Failure21
Injectable Myocardial Matrix Hydrogel Mitigates Negative Left Ventricular Remodeling in a Chronic Myocardial Infarction Model21
Bias in Medicine21
Selective Interleukin-6 Trans-Signaling Blockade Is More Effective Than Panantagonism in Reperfused Myocardial Infarction21
Effect of Crizanlizumab, a P-Selectin Inhibitor, in COVID-1921
Precision Medicine in COVID-19: IL-1β a Potential Target21
Characterization of Cardiac Sympathetic Nervous System and Inflammatory Activation in HFpEF Patients20
Estrogen Receptor-α Non-Nuclear Signaling Confers Cardioprotection and Is Essential to cGMP-PDE5 Inhibition Efficacy20
Clinical Interpretation and Management of Genetic Variants20
Cardio-Oncology20
Genetic Risk Stratification19
Lipoprotein(a) Cellular Uptake Ex Vivo and Hepatic Capture In Vivo Is Insensitive to PCSK9 Inhibition With Alirocumab19
Rejuvenation of Senescent Endothelial Progenitor Cells by Extracellular Vesicles Derived From Mesenchymal Stromal Cells19
In Mice Subjected to Chronic Stress, Exogenous cBIN1 Preserves Calcium-Handling Machinery and Cardiac Function18
Animal Models of Neointimal Hyperplasia and Restenosis18
Multiorgan Damage in Patients With COVID-1918
Paclitaxel Drug-Coated Balloon Angioplasty Suppresses Progression and Inflammation of Experimental Atherosclerosis in Rabbits18
H2 Inhibits the Formation of Neutrophil Extracellular Traps18
Differential Effects of Sacubitril/Valsartan on Diastolic Function in Mice With Obesity-Related Metabolic Heart Disease17
With No Lysine Kinase 1 Promotes Metabolic Derangements and RV Dysfunction in Pulmonary Arterial Hypertension17
Prasugrel Versus Ticagrelor in Patients With CYP2C19 Loss-of-Function Genotypes17
Translation of New and Emerging Therapies for Genetic Cardiomyopathies17
Glycation and Serum Albumin Infiltration Contribute to the Structural Degeneration of Bioprosthetic Heart Valves17
Quantitative Proteomic Analysis of Diabetes Mellitus in Heart Failure With Preserved Ejection Fraction17
Heart Failure in Humans Reduces Contractile Force in Myocardium From Both Ventricles17
Acute Kidney Injury Results in Long-Term Diastolic Dysfunction That Is Prevented by Histone Deacetylase Inhibition17
Human Dorsal Root Ganglion Stimulation Reduces Sympathetic Outflow and Long-Term Blood Pressure17
Activation of Oxytocin Neurons Improves Cardiac Function in a Pressure-Overload Model of Heart Failure16
Cardiovascular Disease in Duchenne Muscular Dystrophy16
Macrophage Polarization as a Novel Therapeutic Target for Endovascular Intervention in Peripheral Artery Disease16
Clec4e-Receptor Signaling in Myocardial Repair After Ischemia-Reperfusion Injury16
Absence of NLRP3 Inflammasome in Hematopoietic Cells Reduces Adverse Remodeling After Experimental Myocardial Infarction16
Rivaroxaban, a Direct Oral Factor Xa Inhibitor, Attenuates Atherosclerosis by Alleviating Factor Xa–PAR2-Mediated Autophagy Suppression16
Dysbiosis and Intestinal Barrier Dysfunction in Pediatric Congenital Heart Disease Is Exacerbated Following Cardiopulmonary Bypass15
HIV, Combination Antiretroviral Therapy, and Vascular Diseases in Men and Women15
PERK Inhibition Mitigates Restenosis and Thrombosis15
Systems Analysis Implicates WAVE2 Complex in the Pathogenesis of Developmental Left-Sided Obstructive Heart Defects15
Interaction of Autotaxin With Lipoprotein(a) in Patients With Calcific Aortic Valve Stenosis14
Highly Reactive Isolevuglandins Promote Atrial Fibrillation Caused by Hypertension14
Research Opportunities in Autonomic Neural Mechanisms of Cardiopulmonary Regulation14
Conduits’ Biology Regulates the Outcomes of Coronary Artery Bypass Grafting14
Development of Tissue Engineered Heart Valves for Percutaneous Transcatheter Delivery in a Fetal Ovine Model14
Finding a Needle in a Haystack14
Update on Cardioprotective Strategies for STEMI14
Migraine in Patients Undergoing PFO Closure13
Cardiac Endocrinology13
Efficacy of a Novel Mitochondrial-Derived Peptide in a Porcine Model of Myocardial Ischemia/Reperfusion Injury13
Direct Interstitial Decongestion in an Animal Model of Acute-on-Chronic Ischemic Heart Failure13
Dynamic Augmentation of Left Ventricle and Mitral Valve Function With an Implantable Soft Robotic Device13
A Phase 1 Dose-Escalation Study of the Cardiac Myosin Inhibitor Aficamten in Healthy Participants13
Plasma Proteomics of COVID-19–Associated Cardiovascular Complications13
STOP-HF Trial12
Molecular Signature of HFpEF12
Safety and Tolerability of Nicotinamide Riboside in Heart Failure With Reduced Ejection Fraction12
Metabolomic Signature of Human Aortic Valve Stenosis12
Implications of Iron Deficiency in STEMI Patients and in a Murine Model of Myocardial Infarction12
Long-Term Strenuous Exercise Promotes Vascular Injury by Selectively Damaging the Tunica Media12
Human Cardiac Pericytes Are Susceptible to SARS-CoV-2 Infection12
Exercise Training and Revascularization in the Management of Symptomatic Peripheral Artery Disease12
Heart Failure With Preserved Ejection Fraction in Women11
Cardiac Xenotransplantation11
Cardiovascular Research in Friedreich Ataxia11
Restoration of Cardiac Function After Myocardial Infarction by Long-Term Activation of the CNS Leptin-Melanocortin System11
Clinical Phenotypes of Heart Failure With Preserved Ejection Fraction to Select Preclinical Animal Models11
Hyperadhesive von Willebrand Factor Promotes Extracellular Vesicle-Induced Angiogenesis11
Update to Drugs, Devices, and the FDA11
Role of Oxidative Stress and Autophagy in Thoracic Aortic Aneurysms11
Myocardial Injury and Altered Gene Expression Associated With SARS-CoV-2 Infection or mRNA Vaccination11
3-Dimensional Bioprinting of Cardiovascular Tissues11
β-Arrestin–Biased AT1 Agonist TRV027 Causes a Neonatal-Specific Sustained Positive Inotropic Effect Without Increasing Heart Rate11
Genetic Ablation of the DNA Damage Response Pathway Attenuates Lamin-Associated Dilated Cardiomyopathy in Mice11
In Situ Immune Profiling of Heart Transplant Biopsies Improves Diagnostic Accuracy and Rejection Risk Stratification11
MLb-LDLr10
Proteolysis of Von Willebrand Factor Influences Inflammatory Endothelial Activation and Vascular Compliance in Atherosclerosis10
In Vivo Imaging of Venous Thrombus and Pulmonary Embolism Using Novel Murine Venous Thromboembolism Model10
PARP1-PKM2 Axis Mediates Right Ventricular Failure Associated With Pulmonary Arterial Hypertension10
TRAF2, an Innate Immune Sensor, Reciprocally Regulates Mitophagy and Inflammation to Maintain Cardiac Myocyte Homeostasis10
Design of the β3-Adrenergic Agonist Treatment in Chronic Pulmonary Hypertension Secondary to Heart Failure Trial10
Parkin Insufficiency Accentuates High-Fat Diet–Induced Cardiac Remodeling and Contractile Dysfunction Through VDAC1-Mediated Mitochondrial Ca2+ Overload10
Landscape of Mentorship and its Effects on Success in Cardiology10
Inflammatory Macrophage Interleukin-1β Mediates High-Fat Diet-Induced Heart Failure With Preserved Ejection Fraction10
COVID-19 Clinical Trials10
Utilization and Potential of RNA-Based Therapies in Cardiovascular Disease10
Targeting Myocardial Mitochondria-STING-Polyamine Axis Prevents Cardiac Hypertrophy in Chronic Kidney Disease9
Inefficient Batteries in Heart Failure9
PTP1B Inhibition Improves Mitochondrial Dynamics to Alleviate Calcific Aortic Valve Disease Via Regulating OPA1 Homeostasis9
Glucagon-Like Peptide-1 Receptor Regulates Thromboxane-Induced Human Platelet Activation9
Novel IVC Doraya Catheter Provides Congestion Relief in Patients With Acute Heart Failure9
Abnormalities in the Von Willebrand-Angiopoietin Axis Contribute to Dysregulated Angiogenesis and Angiodysplasia in Children With a Glenn Circulation9
Translating Imaging Into 3D Printed Cardiovascular Phantoms9
LncRNA-ZFAS1 Promotes Myocardial Ischemia-Reperfusion Injury Through DNA Methylation-Mediated Notch1 Down-Regulation in Mice8
Acute Ischemia Alters Human Pericardial Fluid Immune Cell Composition8
Immune Profiling Reveals Decreases in Circulating Regulatory and Exhausted T Cells in Human Hypertension8
High-Fat Diet Enhances Neutrophil Adhesion in LDLR-Null Mice Via Hypercitrullination of Histone H38
Fir(e)ing the Rhythm8
Association Between Thrombogenicity Indices and Coronary Microvascular Dysfunction in Patients With Acute Myocardial Infarction8
Short-Chain Carbon Sources8
Heart Failure With Reduced Ejection Fraction Is Characterized by Systemic NEP Downregulation8
The Programmed Death-1 Signaling Axis Modulates Inflammation and LV Structure/Function in a Stress-Induced Cardiomyopathy Model8
SCUBE1 Controls BMPR2-Relevant Pulmonary Endothelial Function8
Can a Biohybrid Patch Salvage Ventricular Function at a Late Time Point in the Post-Infarction Remodeling Process?8
Phosphorylcholine Antibodies Preserve Cardiac Function and Reduce Infarct Size by Attenuating the Post-Ischemic Inflammatory Response8
Therapeutic Antibody Against Phosphorylcholine Preserves Coronary Function and Attenuates Vascular 18F-FDG Uptake in Atherosclerotic Mice8
Comprehensive Assessment of High-Risk Plaques by Dual-Modal Imaging Catheter in Coronary Artery8
Micro RNA-411 Expression Improves Cardiac Phenotype Following Myocardial Infarction in Mice8
Apolipoprotein M Attenuates Anthracycline Cardiotoxicity and Lysosomal Injury8
Changes in Myocardial Microstructure and Mechanics With Progressive Left Ventricular Pressure Overload8
Mechanisms of the “No-Reflow” Phenomenon After Acute Myocardial Infarction7
Cardiac Sympathetic-Parasympathetic Interaction7
Immunometabolism at the Heart of Cardiovascular Disease7
Cardiac Mesenchymal Stem Cells Promote Fibrosis and Remodeling in Heart Failure7
Transcatheter-Delivered Expandable Bioresorbable Polymeric Graft With Stenting Capacity Induces Vascular Regeneration7
A Role for Polo-Like Kinase 4 in Vascular Fibroblast Cell-Type Transition7
A Cardiac Amino-Terminal GRK2 Peptide Inhibits Maladaptive Adipocyte Hypertrophy and Insulin Resistance During Diet-Induced Obesity7
Abnormal Flow Conditions Promote Endocardial Fibroelastosis Via Endothelial-to-Mesenchymal Transition, Which Is Responsive to Losartan Treatment7
COVID-19 and the Heart7
Splanchnic Nerve Ablation for Volume Management in Heart Failure7
The Effect of Estrogen on Intracellular Ca2+ and Na+ Regulation in Heart Failure7
Ketone Bodies Rescue Mitochondrial Dysfunction Via Epigenetic Remodeling6
β-Arrestin–Mediated Angiotensin II Type 1 Receptor Activation Promotes Pulmonary Vascular Remodeling in Pulmonary Hypertension6
Loop Diuretics Inhibit Renal Excretion of Trimethylamine N-Oxide6
Septal Reduction Using Transvenous Intramyocardial Cerclage Radiofrequency Ablation6
Data Safety and Monitoring Boards Should Be Required for Both Early- and Late-Phase Clinical Trials6
FYCO1 Regulates Cardiomyocyte Autophagy and Prevents Heart Failure Due to Pressure Overload In Vivo6
Inflammasome Signaling, Thromboinflammation, and Venous Thromboembolism6
DAPA-CKD6
Dynamic Multiscale Regulation of Perfusion Recovery in Experimental Peripheral Arterial Disease6
Cardiac Pulmonary Nerve Stimulation (CPNSTM)6
Linagliptin, A Xanthine-Based Dipeptidyl Peptidase-4 Inhibitor, Ameliorates Experimental Autoimmune Myocarditis6
The National Institute of Allergy and Infectious Diseases Decision to Stop the Adaptive COVID-19 Trial6
Specialized Proresolving Mediators Protect Against Experimental Autoimmune Myocarditis by Modulating Ca2+ Handling and NRF2 Activation6
SARS-CoV-2 and Bats6
Western Diet Causes Heart Failure With Reduced Ejection Fraction and Metabolic Shifts After Diastolic Dysfunction and Novel Cardiac Lipid Derangements6
Sex-Dependent Effect of Platelet Nitric Oxide6
Intermittent Fasting Activates AMP-Kinase to Restructure Right Ventricular Lipid Metabolism and Microtubules6
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