JACC-Basic to Translational Science

Article	Citations
Recognizing Early Career Translational Investigators	126
Unveiling the PGAM5-ANGPTL3 Axis	110
Reducing Plasma Factor XI Concentration With siRNA Technology	91
CXC-Chemokine-Receptor-Type-5 Expression on Circulating Naive B Cells Predicts Improvement After Cardiac Resynchronization Therapy	78
When Off-Target Is the Target	72
Full Issue PDF	68
JACC: Basic to Translational Science 2016-2025	67
Evaluation of Treatment Effect of Sirolimus on Pediatric Pulmonary Vein Stenosis Using a Neonatal Rat Model Induced by Bilateral Pulmonary Vein Banding	60
Therapeutic CCR2 Blockade Prevents Inflammation and Alleviates Myxomatous Valve Disease in Marfan Syndrome	56
Is it Time to Abandon the Use of P-Values in Early Phase Translational Trials: Why (Effect) Size Matters	51
Electroanatomical Navigation to Minimize Contrast Medium or X-Rays During Stenting	51
Validation of a Novel Renal Denervation System With Cryoablation	51
Editorial Board	49
Mitochondrial DNA in Uremia and New Targets to Treat Myocardial Hypertrophy in the Cardiorenal Syndrome	48
New Insights Into the Role of GSK-3 in the Regulation of Human Cardiac Electrophysiology	45
Targeting Syntaxin 17 to Improve Mitophagy in Heart Failure	44
PD-1 Checkmate and the 2-Edged Sword of the Immune System	40
Reading a Good Transcript Soothes MYZAPed Heart	40
FULL ISSUE PDF	39
Is Laser Doppler Perfusion Imaging Truly a “Gold Standard” for Preclinical Peripheral Artery Disease Research?	39
A Potential New Therapeutic Direction for Fibrosis in the Injured Heart Orchestrated by Cardiac MSCs	39
Low-Grade Inflammation in Long COVID Syndrome Sustains a Persistent Platelet Activation Associated With Lung Impairment	38
Right Heart Failure in Mice Upon Pressure Overload Is Promoted by Mitochondrial Oxidative Stress	37
Interorganellar Ca2+ Flux Assessment by Flow Cytometry Reveals an Altered Mitochondrial Ca2+ Homeostasis in Circulating Lymphocytes of STEMI Patients	37
H2 Inhibits the Formation of Neutrophil Extracellular Traps	36

1-Year Patency of Biorestorative Polymeric Coronary Artery Bypass Grafts in an Ovine Model	34
Full Issue PDF	34
Addressing the Reproducibility Crisis in Science	33
New Drug-Coated Balloons on the Horizon	33
TCF7L1 Accelerates Smooth Muscle Cell Phenotypic Switching and Aggravates Abdominal Aortic Aneurysms	32
Therapeutic Efficacy of a Novel Pharmacologic GRK2 Inhibitor in Multiple Animal Models of Heart Failure	32
SIRT1 Ameliorates Lamin A/C Deficiency-Induced Cardiac Dysfunction by Promoting Mitochondrial Bioenergetics	32
Characterizing Adrenergic Regulation of Glucose Transporter 4-Mediated Glucose Uptake and Metabolism in the Heart	32
Full Issue PDF	31
The Reduction of COMP Serves as a Predictor for Warning of Aortic Dissection Progression	31
Cardiomyocyte Alpha-1A Adrenergic Receptors Mitigate Postinfarct Remodeling and Mortality by Constraining Necroptosis	31
Recognizing Early Career Translational Investigators	31
Is Endogenous Fibrinolysis a Major Player in Occurrence of Atherothrombotic Events Following Acute Myocardial Infarction?	31
PDGF-AB Reduces Myofibroblast Differentiation Without Increasing Proliferation After Myocardial Infarction	30
Antibody Matrimony in a Duel of Hearts	30
6-Month Evaluation of a Transcatheter Aortic Valve (Myval) in a Novel Ovine, Supra-Aortic Banding Model	30
ApoM Activates Autophagy and Suppresses Lyosomal Lethargy to Combat Doxorubicin Cardiomyopathy	30
Inflammasome Signaling, Thromboinflammation, and Venous Thromboembolism	29
Interferon Interrupted	28
Soluble Programmed Death-1 Predicts Clinical Outcome After STEMI	27
Shear-Thinning Hydrogel for Delayed Delivery of a Small Molecule Metalloproteinase Inhibitor Attenuates Myocardial Infarction Remodeling	27
Epigenetic Regulation of Heart-ECHS	26
Editorial Board	26
A Differentiated Approach Delivering Targeted Thrombectomy for VTE	25
Should All Translational Scientists Be Swifties?	25
Reply	25
The Farm to Table HFpEF Kitchen	25
Large Animal Models for Transcatheter Heart Valve Prosthesis Development	24
Reply	24
Exosome-Mediated Angiogenesis Underlies LVAD-Induced Bleeding in Patients With End-Stage Heart Failure	24
Full Issue Pdf	23
From Colon to Aortic Aneurysm: Trek of the Treg	23
Determinants of Endogenous Fibrinolysis in Whole Blood Under High Shear in Patients With Myocardial Infarction	23
Regions of Highly Recurrent Electrogram Morphology With Low Cycle Length Reflect Substrate for Atrial Fibrillation	23
Red Blood Cell-Mediated Cardioprotection Is Impaired in ST-Segment Elevation Myocardial Infarction Patients With Anemia	23
Editorial Board	22
Endocardial Fibrosis Elastosis	22
Lower Extremity Lymphatic Flow/Drainage Assessment by Indocyanine Green Fluorescent Lymphography in Heart Failure Patients	21
ATP-Citrate Lyase in Heart Failure	21
C-Type Natriuretic Peptide in Essential Hypertension	21
When Facts Become Forbidden	21
A Novel LncRNA SNHG3 Promotes Osteoblast Differentiation Through BMP2 Upregulation in Aortic Valve Calcification	19
Inhibiting Serotonin to Treat Pulmonary Arterial Hypertension	19
TRAF2, an Innate Immune Sensor, Reciprocally Regulates Mitophagy and Inflammation to Maintain Cardiac Myocyte Homeostasis	19
Phosphoglycerate Mutase 5 Is Important Mediator for Instigating Arterial Lipid Accumulation and Aggravating Atherosclerosis	19
From Risk to Remedy?	19
Pulsatile ECMO	18
Nitric Oxide Releasing Nanomaterials for Cardiovascular Applications	18
Glucagon-Like Peptide-1 Receptor Regulates Thromboxane-Induced Human Platelet Activation	18
Intermittent Fasting Activates AMP-Kinase to Restructure Right Ventricular Lipid Metabolism and Microtubules	18

Fir(e)ing the Rhythm	18
Proteomics of Large Artery Stiffness	18
The Virtual Patient Simulator	17
Full Issue PDF	17
Tissue Engineered Vascular Grafts	16
The Impact of Semaglutide on Cardiac Mass and Function Requires Further Investigation	16
Full Issue Pdf	16
The Past, Present, and Promising Future of Direct Cardiac Compression Devices	16
Reassessing the Mechanisms of PLN-R14del Cardiomyopathy	16
Real-Time Revolution	16
JACC: Basic to Translational Science Top Reviewers 2022: With Appreciation and Gratitude	15
Full Issue PDF	15
Neuregulin-1β Improves Uremic Cardiomyopathy and Renal Dysfunction in Rats	15
Full Issue Pdf	15
Full Issue PDF	15
Noninvasive Cardiovascular Imaging in Preclinical Research	15
Acute Glycogen Synthase Kinase-3 Inhibition Modulates Human Cardiac Conduction	15
Full Issue PDF	14
A Novel Pathway of Platelet Activation in ACS Mediated by LL-37 Immunoglobulin G Autoantibody Immune Complexes	14
CD14 Blockade Modulates Macrophage-Mediated Immunological Injury in a Translational Model of Reperfused ST-Segment Elevation Myocardial Infarction	14
Small Molecule Activators of Mitochondrial Fusion Prevent Congenital Heart Defects Induced by Maternal Diabetes	14
Reduced Proteolytic Cleavage of von Willebrand Factor Leads to Aortic Valve Stenosis and Load-Dependent Ventricular Remodeling	14
Cardiac Spinal Afferent Denervation Attenuates Renal Dysfunction in Rats With Cardiorenal Syndrome Type 2	14
IL-6 Inhibitors and TNF Inhibitors	14
Ticagrelor Antibiotic Effect	14
Propionate Alleviates Abdominal Aortic Aneurysm by Modulating Colonic Regulatory T-Cell Expansion and Recirculation	14
Pulsatile Ventricular Assist Platform	14
Editorial Board	13
Reverse Translation of Pericardial Access	13
Editorial Board	13
Introducing the 2024 Transcatheter Cardiovascular Therapeutics (TCT) Shark Tank Presentations	13
Quality Over Quantity	13
Full Issue PDF	13
Where Comity in Science Goes to Die	13
Decoding MTSS1	12
Charting New Real Estate	12
Editorial Board	12
TIMD4hiMHCⅡhi Macrophages Preserve Heart Function Through Retnla	12
Targeting Myocardial Mitochondria-STING-Polyamine Axis Prevents Cardiac Hypertrophy in Chronic Kidney Disease	12
Synbiotics and Gut-Heart Axis in Cardiometabolic Disease	12
JACC: Basic to Translational Science 2024 Thomas Force Young Investigator Award Winner	12
Turn(over) the Page	12
Structural and Functional Adaptations to Exercise Training	12
FNDC4 Prevents Aging-Related Cardiac Dysfunction	11
Towards Metabolomic-Based Precision Approaches for Classifying and Treating Heart Failure	11
GLP-1 Receptor Agonists, the Holy Grail Preventing Atrial Fibrillation in Patients With T2D?	11
Iron Overload via Heme Degradation in the Endoplasmic Reticulum Triggers Ferroptosis in Myocardial Ischemia-Reperfusion Injury	11
Macrophage Mayhem in Aortic Aneurysm	11
A Cardiac Amino-Terminal GRK2 Peptide Inhibits Maladaptive Adipocyte Hypertrophy and Insulin Resistance During Diet-Induced Obesity	11
Pharmacological Enhancement of Integrated Stress Response Confers Protection in Calcific Aortic Valve Disease	11
Experimental Models of Hypertrophic Cardiomyopathy	11
Full Issue PDF	11
Partial Heart Transplant Growth and Hemodynamic Function in Piglets	11
Autonomic Modulation of Atrial Fibrillation	11
Editorial Board	11
Mesenchymal Stromal Cell Delivery Via Cardiopulmonary Bypass Provides Neuroprotection in a Juvenile Porcine Model	11
Remembering Ada L. Steininger	11
Recurrent Adrenergic Stress Provokes Persistent Myocarditis in PD-1–Deficient Mice	10
Tit for TAK1	10
Full Issue PDF	10
Shielding the Heart	10
Development of a Peripherally Restricted 5-HT2B Partial Agonist for Treatment of Pulmonary Arterial Hypertension	10
Inhibition of Factor XI Using RBD4059	10
BAG3 in the Heart	10
In Vivo Efficacy of an Adhesive Bioresorbable Patch to Treat Aortic Dissections	10
Continuous Monitoring of Blood Pressure and Vascular Hemodynamic Properties With Miniature Extravascular Hall-Based Magnetic Sensor	10
Effect of Semaglutide on Epicardial Adipogenesis and hiPSC-Atrial Cardiomyocytes New Hope in Targeting Epicardial Adipose Tissue	10
Who Should Be Accountable for Scientific Accountability?	10
Atrial Metabolic Stress	10
Publisher's Note	10
Differential BMP Signaling Mediates the Interplay Between Genetics and Leaflet Numbers in Aortic Valve Calcification	10
Minimally Invasive Aortic Regurgitation Surgery	10
Paradoxical Effect of Caloric Restriction on Overload-Induced Muscle Growth in Diastolic Heart Failure	10
Negative Impact of TET2 Mutations on Long-Term Survival After Transcatheter Aortic Valve Replacement	10
Recognizing Early Career Translational Investigators	10
Deficiency of GDF-11 Accelerates TAC-Induced Heart Failure by Impairing Cardiac Angiogenesis	10
The Cardiac Circadian Clock	9
Myocardial Infarction Suppresses Protein Synthesis and Causes Decoupling of Transcription and Translation	9
Safety and Tolerability of Nicotinamide Riboside in Heart Failure With Reduced Ejection Fraction	9
Introducing the 2024 THT Shark Tank Edition of JACC: Basic to Translational Science	9

Parkin Insufficiency Accentuates High-Fat Diet–Induced Cardiac Remodeling and Contractile Dysfunction Through VDAC1-Mediated Mitochondrial Ca2+ Overload	9
Myocardial Infarction Platelet Gene Expression Signatures in Women	9
Left Atrial Glucose Metabolism Evaluation by 18F-FDG-PET in Persistent Atrial Fibrillation and in Sinus Rhythm	9
Recognizing Early Career Translational Investigators	8
Cardiac Adrenergic Activation in Heart Failure With Preserved Ejection Fraction	8
New Insights in the Pathology of Chronic Thromboembolic Pulmonary Hypertension	8
The Imperative to Enhance Cost-Effectiveness for Cardiovascular Therapeutic Development	8
Intrinsic and Extrinsic Contributors to the Cardiac Benefits of Exercise	8
New Insights Into the Therapy for Lamin-Associated Dilated Cardiomyopathy	8
Translating Imaging Into 3D Printed Cardiovascular Phantoms	8
Full Issue PDF	8
Platelet Gene Expression in Systemic Lupus Erythematosus and Cardiovascular Health	8
Low-Grade Inflammation	8
A (Alpha1-Adrenergic Receptors), B (Blocking Alpha1-Adrenergic Receptors), C (Catecholamines)	8
The Quest for an Early Marker of Anthracycline-Induced Cardiotoxicity	8
Editorial Board	8
High Maternal Glycine Levels Increase the Risk of Developing Atrial Septal Defect in the Offspring	8
Erythrocytes Induce Vascular Dysfunction in COVID-19	8
Will Gene Editing Orphanize Rare Diseases?	7
Cardiovascular Disease in Duchenne Muscular Dystrophy	7
Proteome-Wide Genetic Investigation of Large Artery Stiffness	7
Syntaxin 17 Protects Against Heart Failure Through Recruitment of CDK1 to Promote DRP1-Dependent Mitophagy	7
Editorial Board	7
Homophilic Interaction Between Transmembrane-JAM-A and Soluble JAM-A Regulates Thrombo-Inflammation	7
Heart Failure Solutions	7
Mitophagy Regulators as Novel Targets in Sepsis-Induced Myocardial Dysfunction	7
Clinical Phenotypes of Heart Failure With Preserved Ejection Fraction to Select Preclinical Animal Models	7
A Novel Device for Tricuspid Regurgitation Reduction Featuring 3-Dimensional Leaflet and Atraumatic Anchor	7
Editorial Board	7
Full Issue PDF	7
Controlled Right Ventricular Pressure Overload Can Rescue Left Ventricular Dysfunction by Promoting Biventricular Adaptive Hypertrophy	7
Editorial Board	7
Estrogen Influences Human Microvascular Endothelial Function Via Sex-Specific Regulation of Sphingolipids	6
Transvalvular Unloading Mitigates Ventricular Injury Due to Venoarterial Extracorporeal Membrane Oxygenation in Acute Myocardial Infarction	6
Platelet-Derived Growth Factors	6
The Antioxidant Vitamin B12 Analogue Cobinamide as a Treatment for Marfan Syndrome	6
The Emerging Role of Circular RNAs in Cardio-Oncology	6
Inhibition of Soluble Epoxide Hydrolase Reduces Inflammation and Myocardial Injury in Arrhythmogenic Cardiomyopathy	6
Cardiac TRPM7 Causes Diabetic Heart Failure With Preserved Ejection Fraction	6
Targeting the Autophagy-Lysosome Pathway in a Pathophysiologically Relevant Murine Model of Reversible Heart Failure	6
Focusing on the Native Matrix Proteins in Calcific Aortic Valve Stenosis	6
Red Blood Cell Transfusion and Cardiac Surgery–Associated Acute Kidney Injury	6
PCSK9 Inhibition	6
Are 3 Aorta Pumps Better Than 1 Transaortic to Preserve Von Willebrand Factor?	6
Deleterious Anti-Inflammatory Macrophage Recruitment in Early Post-Infarction Phase	6
Associations of Epigenetic Age Acceleration With CVD Risks Across the Lifespan	6
Hydrogen Sulfide Deficiency and Therapeutic Targeting in Cardiometabolic HFpEF	6
In Memory of Dr Gary D. Lopaschuk, PhD (1955–2025)	6
Decreased FAM13B Expression Increases Atrial Fibrillation Susceptibility by Regulating Sodium Current and Calcium Handling	6
Full Issue PDF	6
JACC Journals’ Pathway Forward With AI Tools	6
Stimulation of Erythrocyte Soluble Guanylyl Cyclase Induces cGMP Export and Cardioprotection in Type 2 Diabetes	6
Deep Image Segmentation for Cardiomyocyte Proliferation	6
A New Ex Vivo Model to Study Cardiac Fibrosis in Whole Mouse Hearts	6
Editorial Board	6