JACC-Basic to Translational Science

Papers
(The TQCC of JACC-Basic to Translational Science is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-02-01 to 2025-02-01.)
ArticleCitations
HIF-1α Cardioprotection in COVID-19 Patients154
Mutations of Splicing Regulator RBM20 in Atrial Fibrillation117
Anemia, Increased Shear Stress, and the Progression of Aortic Stenosis84
Comprehensive RV Hemodynamic Assessment With Pressure-Volume Analysis During Impella Support72
Myocardial Matrix Hydrogels Mitigate Negative Remodeling and Improve Function in Right Heart Failure Model65
Cardiac Lymphatic Insufficiency Leads to Diastolic Dysfunction Via Myocardial Morphologic Change62
Cardiac GRK2 and the Communicative Axis Between Heart and Fat61
Renal Dysfunction in Heart Failure59
Editorial Board58
Cardioprotection Achieved Through Overexpression of Relaxin Receptors57
Stability of Ready-to-Use Solutions of Acetylcholine for Intracoronary Provocative Testing55
Full Issue PDF52
Low-Grade Inflammation in Long COVID Syndrome Sustains a Persistent Platelet Activation Associated With Lung Impairment50
Targeting the Gut-Heart Axis Improves Cardiac Remodeling in a Clinical Scale Model of Cardiometabolic Syndrome46
Is Laser Doppler Perfusion Imaging Truly a “Gold Standard” for Preclinical Peripheral Artery Disease Research?42
Full Issue Pdf41
A Potential New Therapeutic Direction for Fibrosis in the Injured Heart Orchestrated by Cardiac MSCs40
Full Issue PDF35
Full Issue PDF32
Exercise Training and Revascularization in the Management of Symptomatic Peripheral Artery Disease32
Recognizing Early Career Translational Investigators32
Electroanatomical Navigation to Minimize Contrast Medium or X-Rays During Stenting31
Myopathic Cardiac Genotypes Increase Risk for Myocarditis31
It’s Time to Put the Term “Pulmonary Vasodilators” to Rest29
Translational Insights in Coronary Microvascular Disease27
New Insights in the Pathology of Chronic Thromboembolic Pulmonary Hypertension26
Device-Based Ventricular Reverse Remodeling26
Fueling the Failing Heart26
A (Alpha1-Adrenergic Receptors), B (Blocking Alpha1-Adrenergic Receptors), C (Catecholamines)26
Can Paclitaxel Coated Balloons Have a Deep Impact on Critical Limb Ischemia?25
FULL ISSUE PDF25
Remembering Jeff Robbins25
Immune Cells, Superheroes or Villains?24
New Insights Into the Role of GSK-3 in the Regulation of Human Cardiac Electrophysiology24
Editorial Board23
Modeling Acute Pericarditis22
Full Issue PDF21
Full Issue PDF21
Tissue Rings PLOD Out a Second Hit in Becker Muscular Dystrophy21
Clonal Expansion in Cardiovascular Pathology21
Dynamic Multiscale Regulation of Perfusion Recovery in Experimental Peripheral Arterial Disease20
Editorial Board20
Introducing the 2024 THT Shark Tank Edition of JACC: Basic to Translational Science20
The Efficacy of Risk Factor Modification Compared to NAD+ Repletion in Diastolic Heart Failure20
JACC: Basic to Translational Science 2023 Thomas Force Young Investigator Award Winner20
Association Between Thrombogenicity Indices and Coronary Microvascular Dysfunction in Patients With Acute Myocardial Infarction19
Editorial Board19
New Insights Into the Therapy for Lamin-Associated Dilated Cardiomyopathy19
A Subcutaneous Multiparameter Sensor With Integrated Interstitial Fluid Pressure Measurement for Remote Heart Failure Monitoring19
Junctional Ectopic Tachycardia Caused by Junctophilin-2 Expression Silencing Is Selectively Sensitive to Ryanodine Receptor Blockade18
Therapeutic CCR2 Blockade Prevents Inflammation and Alleviates Myxomatous Valve Disease in Marfan Syndrome18
JACC: Basic to Translational Science Top Reviewers 2023: With Appreciation and Gratitude17
Semaglutide in Heart Failure With Preserved Ejection Fraction17
Low-Grade Inflammation17
Structure-Based Probe Reveals the Presence of Large Transthyretin Aggregates in Plasma of ATTR Amyloidosis Patients17
Editorial Board16
Editorial Board16
Is it Time to Abandon the Use of P-Values in Early Phase Translational Trials: Why (Effect) Size Matters16
Genetic Testing in Familial Hypercholesterolemia16
What Are the Clinical Implications of the SARS-CoV-2 Variants16
Cardiovascular Disease in Duchenne Muscular Dystrophy15
Mitochondrial DNA in Uremia and New Targets to Treat Myocardial Hypertrophy in the Cardiorenal Syndrome15
Clinical Implication of Transvalvular Unloading With Venoarterial Extracorporeal Membrane Oxygenation Support in Acute Myocardial Infarction15
miR-590-3p Overexpression Improves the Efficacy of hiPSC-CMs for Myocardial Repair15
Targeting Syntaxin 17 to Improve Mitophagy in Heart Failure15
Viewing Pulmonary Arterial Hypertension Pathogenesis and Opportunities for Disease-Modifying Therapy Through the Lens of Biomass15
Reading a Good Transcript Soothes MYZAPed Heart15
Circadian-Regulated Cardiac Metabolism Involves Transcription Factor E4BP415
Beneficial Effects of Low-Intensity Pulsed Ultrasound Therapy on Right Ventricular Dysfunction in Animal Models14
Murine Ischemia Reperfusion Without Endotracheal Intubation or Ventilation14
Autophagy in the LVAD-Supported Heart14
Injectable Myocardial Matrix Hydrogel Mitigates Negative Left Ventricular Remodeling in a Chronic Myocardial Infarction Model14
RBM15 Protects From Myocardial Infarction by Stabilizing NAE113
Shear-Sensitive circRNA-LONP2 Promotes Endothelial Inflammation and Atherosclerosis by Targeting NRF2/HO1 Signaling13
Novel GSK-3β Inhibitor Neopetroside A Protects Against Murine Myocardial Ischemia/Reperfusion Injury13
Primate Model Carrying LMNA Mutation Develops Dilated Cardiomyopathy13
Right Heart Failure in Mice Upon Pressure Overload Is Promoted by Mitochondrial Oxidative Stress13
Cardiac Adrenergic Activation in Heart Failure With Preserved Ejection Fraction13
Direct Interstitial Decongestion in an Animal Model of Acute-on-Chronic Ischemic Heart Failure13
Endothelial Overexpression of TGF-β-Induced Protein Impairs Venous Thrombus Resolution13
The Imperative to Enhance Cost-Effectiveness for Cardiovascular Therapeutic Development13
Exercise Therapy Rescues Skeletal Muscle Dysfunction and Exercise Intolerance in Cardiometabolic HFpEF13
Obesity-Induced Coronary Microvascular Disease Is Prevented by iNOS Deletion and Reversed by iNOS Inhibition13
Percutaneous LAAO and Pulsed-Field Isolation in a Canine Model13
PD-1 Checkmate and the 2-Edged Sword of the Immune System12
Selective FPR2 Agonism Promotes a Proresolution Macrophage Phenotype and Improves Cardiac Structure-Function Post Myocardial Infarction12
Cardiac Transcriptome Remodeling and Impaired Bioenergetics in Single-Ventricle Congenital Heart Disease12
Translating Imaging Into 3D Printed Cardiovascular Phantoms12
Validation of a Novel Renal Denervation System With Cryoablation12
High-Throughput Microscopy Characterization of Rare LDLR Variants12
Extracellular Matrix Protein-1 as a Mediator of Inflammation-Induced Fibrosis After Myocardial Infarction11
1-Year Patency of Biorestorative Polymeric Coronary Artery Bypass Grafts in an Ovine Model11
Genetic Catalytic Inactivation of GRK5 Impairs Cardiac Function in Mice Via Dysregulated P53 Levels11
Sex-Dependent Effect of Platelet Nitric Oxide11
Effect of Crizanlizumab, a P-Selectin Inhibitor, in COVID-1911
The Quest for an Early Marker of Anthracycline-Induced Cardiotoxicity11
Platelets11
Intrinsic and Extrinsic Contributors to the Cardiac Benefits of Exercise10
Targeting Mitochondria Dysfunction in LMNA Cardiomyopathy10
Erythrocytes Induce Vascular Dysfunction in COVID-1910
Correction10
Full Issue PDF9
Non-Cell-Autonomous Cardiomyocyte Regulation Complicates Gene Supplementation Therapy for Lmna-Associated Cardiac Defects in Mice9
When Off-Target Is the Target9
Endothelial Shear Stress Metrics Associate With Proinflammatory Pathways at the Culprit Site of Coronary Erosion9
H2 Inhibits the Formation of Neutrophil Extracellular Traps9
Pericardial Fluid of Patients With Coronary Artery Disease Can Drive Fibrosis Via TGF-Beta Pathway9
Deubiquitinase USP25 Alleviates Obesity-Induced Cardiac Remodeling and Dysfunction by Downregulating TAK1 and Reducing TAK1-Mediated Inflammation9
Linking Physiology and Biology in Plaque Erosion9
CXC-Chemokine-Receptor-Type-5 Expression on Circulating Naive B Cells Predicts Improvement After Cardiac Resynchronization Therapy8
Full Issue PDF8
Instructions for Authors8
Mind the Gap8
Inflammatory Effects of Triglycerides8
Sailing the Uncharted Waters of Familial Hypercholesterolemia LDL Receptor Genetic-Related Variants8
The Emerging Role of Circular RNAs in Cardio-Oncology8
Vent to Prevent?7
Are 3 Aorta Pumps Better Than 1 Transaortic to Preserve Von Willebrand Factor?7
Platelet-Derived Growth Factors7
Full Issue PDF7
Wharton’s Jelly–Mesenchymal Stem Cell–Engineered Conduit for Pulmonary Artery Reconstruction in Growing Piglets7
Full Issue PDF7
Platelets and the Endothelium7
Detecting and Targeting Inflammation in Genetic Cardiomyopathies7
JACC Journals’ Pathway Forward With AI Tools7
RNA m6A-Regulated circ-ZNF609 Suppression Ameliorates Doxorubicin-Induced Cardiotoxicity by Upregulating FTO7
The Antioxidant Vitamin B12 Analogue Cobinamide as a Treatment for Marfan Syndrome7
Shark Attack7
ApoM Activates Autophagy and Suppresses Lyosomal Lethargy to Combat Doxorubicin Cardiomyopathy7
State-of-the-Art Cardiovascular Technology7
Plasminogen Activator Inhibitor-1–Positive Platelet-Derived Extracellular Vesicles Predicts MACE and the Proinflammatory SMC Phenotype7
Integration of Biomarker Polygenic Risk Score Improves Prediction of Coronary Heart Disease6
Transcatheter Pulmonary Artery Banding for HFrEF6
Reply6
More Energy to Relax6
Do Not Lose Your Nerves6
Full Issue PDF6
Heart Failure Solutions6
Noninvasive Stereotactic Radiotherapy for PADN in an Acute Canine Model of Pulmonary Arterial Hypertension6
Deleterious Anti-Inflammatory Macrophage Recruitment in Early Post-Infarction Phase6
Editorial Board6
Full Issue PDF6
Full Issue PDF6
Oral Nitrate and Platelet Reactivity6
SARS-CoV-2 Infects Human Engineered Heart Tissues and Models COVID-19 Myocarditis6
Editorial Board6
Editorial Board6
Editorial Board5
Cardiomyocyte Alpha-1A Adrenergic Receptors Mitigate Postinfarct Remodeling and Mortality by Constraining Necroptosis5
PLucKing at Vascular Fibrosis5
Will Gene Editing Orphanize Rare Diseases?5
Synchronized Diaphragmatic Stimulation for the Treatment of Symptomatic Heart Failure5
Proteomic Analyses Unveil Actionable Disease Pathways in COVID-195
Safety, Feasibility of Controllable Decrease of Vena Cava Pressure by Doraya Catheter in Heart Failure5
Synergizing Light and Machine Learning to Comprehensively Reveal Coronary Plaque Composition5
Reduce, Reuse, Recycle…Unloading, Autophagy, and Myocardial Recovery5
Can We Use Viscoelastic Testing to Evaluate Microvascular Dysfunction in Acute Myocardial Infarction?5
In the Ongoing Conflict Between Ideology and Immunity, Which Side Will Protect the Children From Post-Acute Sequelae of COVID-19?5
Red Blood Cell Transfusion and Cardiac Surgery–Associated Acute Kidney Injury5
The Pursuit of a Perfect Conduit5
BNP and Precision Medicine5
Editorial Board4
Editorial Board4
Feasibility Study of a Novel Transcatheter Tricuspid Annuloplasty System in a Porcine Model4
Reply4
Pleiotropic Effects of Pyruvate Kinase M2 in Right Ventricular Failure and Pulmonary Arterial Hypertension4
CCM Function in the Heart4
Proarrhythmic Remodeling of Atrial Myocyte Ca2+ Handling in Atrial Fibrillation4
New Drug-Coated Balloons on the Horizon4
Spatial Distribution of Calcium Sparks Determines Their Ability to Induce Afterdepolarizations in Human Atrial Myocytes4
Is Endogenous Fibrinolysis a Major Player in Occurrence of Atherothrombotic Events Following Acute Myocardial Infarction?4
A Novel Device for Tricuspid Regurgitation Reduction Featuring 3-Dimensional Leaflet and Atraumatic Anchor4
Transvalvular Unloading Mitigates Ventricular Injury Due to Venoarterial Extracorporeal Membrane Oxygenation in Acute Myocardial Infarction4
Associations of Epigenetic Age Acceleration With CVD Risks Across the Lifespan4
PCSK9-Inhibition to Quench Vascular Injury in Chronic Limb Threatening Ischemia4
TCF7L1 Exacerbates Abdominal Aortic Aneurysm Prevalence and Severity4
Full Issue PDF4
6-Month Evaluation of a Transcatheter Aortic Valve (Myval) in a Novel Ovine, Supra-Aortic Banding Model4
Homophilic Interaction Between Transmembrane-JAM-A and Soluble JAM-A Regulates Thrombo-Inflammation4
Novel Roles for the Transcriptional Repressor E4BP4 in Both Cardiac Physiology and Pathophysiology4
Stimulation of Erythrocyte Soluble Guanylyl Cyclase Induces cGMP Export and Cardioprotection in Type 2 Diabetes4
PCSK9 Inhibition4
Full Issue PDF4
Biochemical Structure and Function of TRAPP Complexes in the Cardiac System3
The Pathogenesis and Long-Term Consequences of COVID-19 Cardiac Injury3
Inflammatory Macrophage Interleukin-1β Mediates High-Fat Diet-Induced Heart Failure With Preserved Ejection Fraction3
Reducing Abdominal Aortic Aneurysm Progression by Blocking Neutrophil Extracellular Traps Depends on Thrombus Formation3
Mechanisms of the “No-Reflow” Phenomenon After Acute Myocardial Infarction3
Editorial Board3
Full Issue PDF3
The Role of NLRP3 Inflammasome in Pericarditis3
Targeting Soluble TGF-β Factors3
PDGF-AB Reduces Myofibroblast Differentiation Without Increasing Proliferation After Myocardial Infarction3
Decreased FAM13B Expression Increases Atrial Fibrillation Susceptibility by Regulating Sodium Current and Calcium Handling3
Association Between Clonal Hematopoiesis and Left Ventricular Reverse Remodeling in Nonischemic Dilated Cardiomyopathy3
Proteome-Wide Genetic Investigation of Large Artery Stiffness3
TCF7L1 Accelerates Smooth Muscle Cell Phenotypic Switching and Aggravates Abdominal Aortic Aneurysms3
PECUU-ECM Patches3
Novel Tryptophan Hydroxylase Inhibitor TPT-001 Reverses PAH, Vascular Remodeling, and Proliferative-Proinflammatory Gene Expression3
Dysbiosis and Intestinal Barrier Dysfunction in Pediatric Congenital Heart Disease Is Exacerbated Following Cardiopulmonary Bypass3
Loss of Cardiac Splicing Regulator RBM20 Is Associated With Early-Onset Atrial Fibrillation3
Crizanlizumab3
Erratum3
Syntaxin 17 Protects Against Heart Failure Through Recruitment of CDK1 to Promote DRP1-Dependent Mitophagy3
SIRT1 Ameliorates Lamin A/C Deficiency-Induced Cardiac Dysfunction by Promoting Mitochondrial Bioenergetics3
A Phase 1 Dose-Escalation Study of the Cardiac Myosin Inhibitor Aficamten in Healthy Participants3
Off-Label Use vs Off-Label Marketing of Drugs3
Molecular Signature of HFpEF3
Addressing the Reproducibility Crisis in Science3
Metabolomic Signatures of Myocardial Glucose Uptake on Fluorine-18 Fluorodeoxyglucose Positron Emission Tomography3
Can a Biohybrid Patch Salvage Ventricular Function at a Late Time Point in the Post-Infarction Remodeling Process?3
The Uses and Misuses of Mendelian Randomization in Clinical and Translational Science3
Apolipoprotein A-I for Cardiac Recovery Post–Myocardial Infarction3
β-Arrestin–Mediated Angiotensin II Type 1 Receptor Activation Promotes Pulmonary Vascular Remodeling in Pulmonary Hypertension3
Clinical Phenotypes of Heart Failure With Preserved Ejection Fraction to Select Preclinical Animal Models3
Semaglutide Reduces Cardiomyocyte Size and Cardiac Mass in Lean and Obese Mice3
Rivaroxaban, a Direct Oral Factor Xa Inhibitor, Attenuates Atherosclerosis by Alleviating Factor Xa–PAR2-Mediated Autophagy Suppression3
Implications of Iron Deficiency in STEMI Patients and in a Murine Model of Myocardial Infarction3
Migraine in Patients Undergoing PFO Closure3
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