OOIR: Observatory of International Research

Papers

(The H4-Index of Bioactive Materials is 71. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)

Article	Citations
Primary and Re-exposure effects of D-enantiomeric peptide on metabolism, diversity, and composition of oral biofilms at different stages of recovery	246
Application of bioactive materials primary cilia as a novel delivery vehicle	240
Outside Front Cover	210
Surface charge adaptive nitric oxide nanogenerator for enhanced photothermal eradication of drug-resistant biofilm infections	189
ROS-responsive nanoparticle delivery of ferroptosis inhibitor prodrug to facilitate mesenchymal stem cell-mediated spinal cord injury repair	188
In situ engineered magnesium alloy implant for preventing postsurgical tumor recurrence	183
Bimetallic clusterzymes-loaded dendritic mesoporous silica particle regulate arthritis microenvironment via ROS scavenging and YAP1 stabilization	172
Cryo-shocked cancer cell microgels for tumor postoperative combination immunotherapy and tissue regeneration	150
Fluorous oligoarginines as supra-enhancers for intracellular and transdermal peptide delivery	150
Artificial cilia for soft and stable surface covalent immobilization of bone morphogenetic protein-2	143
Corrigendum to “Surface modification of electrospun fibers with mechano-growth factor for mitigating the foreign-body reaction” [Bioact. Mater. 6 (9) (2021) 2983–2998]	139
Biomimetic integration of functionally controlled modular tissue building blocks for engineering 3D vascularized adipose tissue	134
Zwitterionic betaines over HEPES as the new generation biocompatible pH buffers for cell culture	130
Bilayer vascular grafts separately loaded with sodium copper chlorophyllin and keratin-based hydrogen sulfide donor with pro-endothelialization, anti-thrombogenicity, anti-inflammation, and anti-calci	128
Immunoregulative coating for scarless healing in anterior cruciate ligament reconstruction	124
Biochemical hallmarks-targeting antineoplastic nanotherapeutics	122
Advances and applications of biomimetic biomaterials for endogenous skin regeneration	122
Application of antibody-conjugated small intestine submucosa to capture urine-derived stem cells for bladder repair in a rabbit model	118
Dual-pathway targeted therapy for Parkinson's disease: Biomimetic nanosomes inhibit ferroptosis and pyroptosis through NLRP3 inflammasome regulation	116
Promoting lacunar bone regeneration with an injectable hydrogel adaptive to the microenvironment	114
Biomimetic fabricated tubular graft in situ immobilized with peptides to restore the vascular structure and regulate the inflammation homeostasis through gastrodin coating	114
A hierarchical MgF2/polyurethane/pitavastatin coating alleviates degradation and enhances endothelialization of bioresorbable magnesium alloy stents	111
Bioprinted constructs that simulate nerve–bone crosstalk to improve microenvironment for bone repair	110
Engineered mesenchymal stem cell-derived small extracellular vesicles for diabetic retinopathy therapy through HIF-1α/EZH2/PGC-1α pathway	108
In situ implantation of type II collagen-based double-layer scaffolds for Articular Osteochondral Regeneration comprising hyaline cartilage and vascularized subchondral bones	108

Bio-integrated scaffold facilitates large bone regeneration dominated by endochondral ossification	105
Enhancing PD-1 blockade in NSCLC: Reprogramming tumor immune microenvironment with albumin-bound statins targeting lipid rafts and mitochondrial respiration	105
Simvastatin/hydrogel-loaded 3D-printed titanium alloy scaffolds suppress osteosarcoma via TF/NOX2-associated ferroptosis while repairing bone defects	103
Electrically conductive biopolymer-based hydrogels and fibrous materials fabricated using 3D printing and electrospinning for cardiac tissue engineering	98
Boosting cartilage repair with silk fibroin-DNA hydrogel-based cartilage organoid precursor	97
Synergistic therapy for pancreatic cancer by deactivating cancer-associated fibroblasts and driving T-cell migration into tumor microenvironment using nanochaperone delivery system	96
CRCs-CAFs crosstalk-targeted nano-delivery system reprograms tumor microenvironment for oxaliplatin resistance reversing and liver metastasis inhibition in colorectal cancer	96
Tailoring the multiscale mechanics of tunable decellularized extracellular matrix (dECM) for wound healing through immunomodulation	94
Piezoresistive MXene/Silk fibroin nanocomposite hydrogel for accelerating bone regeneration by Re-establishing electrical microenvironment	93
Structure-function integrated biodegradable Mg/polymer composites: Design, manufacturing, properties, and biomedical applications	92
Diatomite-incorporated hierarchical scaffolds for osteochondral regeneration	92
Mitochondria-targeted MXene@MnO2-TPP nanoheterostructures for synergistic enhancement of sonodynamic therapy and immunotherapy in osteosarcoma	91
Reprogramming macrophages via immune cell mobilized hydrogel microspheres for osteoarthritis treatments	91
Sonotheranostic nanosideromycin eradicates bacterial biofilm infections via ultrasound-detonated ROS generation and ferroptosis-like death	89
Enhanced healing of critical-sized bone defects using degradable scaffolds with tailored composition through immunomodulation and angiogenesis	89
From hard tissues to beyond: Progress and challenges of strontium-containing biomaterials in regenerative medicine applications	88
Targeting and reprogramming microglial phagocytosis of neutrophils by ginsenoside Rg1 nanovesicles promotes stroke recovery	86
A mitochondria-targeted nanoantioxidant restores alveolar bone homeostasis in periodontitis by quenching ROS and suppressing the cGAS-STING pathway	86
An adhesive and resilient hydrogel for the sealing and treatment of gastric perforation	83
Improving hard metal implant and soft tissue integration by modulating the “inflammatory-fibrous complex” response	83
Enhanced bone regeneration via endochondral ossification using Exendin-4-modified mesenchymal stem cells	82
In situ phosphorus-modified Mg2Ge/Zn-Cu composite with improved mechanical, degradation, biotribological properties, and in vitro and in vivo osteogenesis and osteointegration performance for biodegra	82
Wet-adhesive and antibacterial PAH-TPP coacervates with self-mineralizing capability for cranial flap fixation	82
Progress in bioactive surface coatings on biodegradable Mg alloys: A critical review towards clinical translation	79
Tumor microenvironment-responsive self-assembly of barium titanate nanoparticles with enhanced piezoelectric catalysis capabilities for efficient tumor therapy	78
Strategic advances in Vat Photopolymerization for 3D printing of calcium phosphate-based bone scaffolds: A review	78
Engineering of immunoinstructive extracellular matrices for enhanced osteoinductivity	77
Bioinspired porous microspheres for sustained hypoxic exosomes release and vascularized bone regeneration	77
Decellularized heart extracellular matrix alleviates activation of hiPSC-derived cardiac fibroblasts	77
Advancements in adoptive CAR immune cell immunotherapy synergistically combined with multimodal approaches for tumor treatment	76
Engineered extracellular vesicles for delivery of siRNA promoting targeted repair of traumatic spinal cord injury	76
Combination of biodegradable hydrogel and antioxidant bioadhesive for treatment of breast cancer recurrence and radiation skin injury	75
Engineering biomimetic silk fibroin hydrogel scaffolds with “organic-inorganic assembly” strategy for rapid bone regeneration	75
Immunomodulatory topographies regulate myofibroblast differentiation and influence fibrous encapsulation of glaucoma drainage devices	75
Exosomes loaded a smart bilayer-hydrogel scaffold with ROS-scavenging and macrophage-reprogramming properties for repairing cartilage defect	75
Light-activated nanoclusters with tunable ROS for wound infection treatment	75
Intrinsically bioactive and biomimetic nanoparticle-derived therapies alleviate asthma by regulating multiple pathological cells	75
Janus piezoelectric adhesives regulate macrophage TRPV1/Ca2+/cAMP axis to stimulate tendon-to-bone healing by multi-omics analysis	74
Advances in biomaterial-based tissue engineering for peripheral nerve injury repair	74
Rationally designed approaches to augment CAR-T therapy for solid tumor treatment	73
Engineering mesoporous bioactive glasses for emerging stimuli-responsive drug delivery and theranostic applications	73
Biodegradable magnesium alloy WE43 porous scaffolds fabricated by laser powder bed fusion for orthopedic applications: Process optimization, in vitro and in vivo investigation	73
Charge balance transition enabled Janus hydrogel for robust wet-tissue adhesion and anti-postoperative adhesion	72
A gel microparticle-based self-thickening strategy for 3D printing high-modulus hydrogels skeleton cushioned with PNAGA hydrogel mimicking anisotropic mechanics of meniscus	71
Fabrication and functional validation of a hybrid biomimetic nanovaccine (HBNV) against Kit-mutant melanoma	71
Formulation of pH-responsive PEGylated nanoparticles with high drug loading capacity and programmable drug release for enhanced antibacterial activity	71
Nitric-oxide enriched plasma-activated water inactivates 229E coronavirus and alters antiviral response genes in human lung host cells	71