OOIR: Observatory of International Research

Papers

(The H4-Index of Bioactive Materials is 73. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-10-01 to 2024-10-01.)

Article	Citations
The application of nanoparticles in cancer immunotherapy: Targeting tumor microenvironment	310
Antibacterial approaches in tissue engineering using metal ions and nanoparticles: From mechanisms to applications	268
Mussel-inspired adhesive antioxidant antibacterial hemostatic composite hydrogel wound dressing via photo-polymerization for infected skin wound healing	253
Decellularized extracellular matrix scaffolds: Recent trends and emerging strategies in tissue engineering	230
Poly(lactic-co-glycolic acid)-based composite bone-substitute materials	209
Antibacterial metals and alloys for potential biomedical implants	197
An overview of filtration efficiency through the masks: Mechanisms of the aerosols penetration	191
Accelerated degradation of HAP/PLLA bone scaffold by PGA blending facilitates bioactivity and osteoconductivity	187
Copper single-atom catalysts with photothermal performance and enhanced nanozyme activity for bacteria‐infected wound therapy	186
Bone physiological microenvironment and healing mechanism: Basis for future bone-tissue engineering scaffolds	182
Advanced hydrogels for the repair of cartilage defects and regeneration	177
Biobased polyurethanes for biomedical applications	166
Fabrication of physical and chemical crosslinked hydrogels for bone tissue engineering	162
Multifunctional GelMA platforms with nanomaterials for advanced tissue therapeutics	158
Peptide-based nanomaterials: Self-assembly, properties and applications	155
A mussel-inspired supramolecular hydrogel with robust tissue anchor for rapid hemostasis of arterial and visceral bleedings	143
Anti-inflammatory activity of curcumin-loaded tetrahedral framework nucleic acids on acute gouty arthritis	141
Articular cartilage and osteochondral tissue engineering techniques: Recent advances and challenges	140
Recent research and progress of biodegradable zinc alloys and composites for biomedical applications: Biomechanical and biocorrosion perspectives	137
Mussel-inspired nanozyme catalyzed conductive and self-setting hydrogel for adhesive and antibacterial bioelectronics	132
Bioinspired mineralized collagen scaffolds for bone tissue engineering	130
An intrinsically bioactive hydrogel with on-demand drug release behaviors for diabetic wound healing	130
Advancing application of mesenchymal stem cell-based bone tissue regeneration	129
Reactive oxygen species-based nanomaterials for the treatment of myocardial ischemia reperfusion injuries	127
Microstructure evolution and texture tailoring of reduced graphene oxide reinforced Zn scaffold	123

Chitosan hydrogel incorporated with dental pulp stem cell-derived exosomes alleviates periodontitis in mice via a macrophage-dependent mechanism	121
Mussel-inspired agarose hydrogel scaffolds for skin tissue engineering	119
Wound microenvironment self-adaptive hydrogel with efficient angiogenesis for promoting diabetic wound healing	119
A targeting black phosphorus nanoparticle based immune cells nano-regulator for photodynamic/photothermal and photo-immunotherapy	118
Polydopamine nanoparticle-dotted food gum hydrogel with excellent antibacterial activity and rapid shape adaptability for accelerated bacteria-infected wound healing	118
Nitrogen-doped fluorescence carbon dots as multi-mechanism detection for iodide and curcumin in biological and food samples	117
Construction of multifunctional hydrogel based on the tannic acid-metal coating decorated MoS2 dual nanozyme for bacteria-infected wound healing	116
Biomimetic injectable hydrogel microspheres with enhanced lubrication and controllable drug release for the treatment of osteoarthritis	115
MoS2-based nanocomposites for cancer diagnosis and therapy	113
Biofilm-inspired adhesive and antibacterial hydrogel with tough tissue integration performance for sealing hemostasis and wound healing	112
Recent advances of two-dimensional materials in smart drug delivery nano-systems	111
Exosomes: Small vesicles with big roles in cancer, vaccine development, and therapeutics	105
Modified hyaluronic acid hydrogels with chemical groups that facilitate adhesion to host tissues enhance cartilage regeneration	103
Ultrasmall Fe-doped carbon dots nanozymes for photoenhanced antibacterial therapy and wound healing	102
Reversing cold tumors to hot: An immunoadjuvant-functionalized metal-organic framework for multimodal imaging-guided synergistic photo-immunotherapy	102
Construction of heparin-based hydrogel incorporated with Cu5.4O ultrasmall nanozymes for wound healing and inflammation inhibition	101
Advanced fabrication for electrospun three-dimensional nanofiber aerogels and scaffolds	100
Poly(α-l-lysine)-based nanomaterials for versatile biomedical applications: Current advances and perspectives	99
3D printed silk-gelatin hydrogel scaffold with different porous structure and cell seeding strategy for cartilage regeneration	96
Gold nanorods and nanohydroxyapatite hybrid hydrogel for preventing bone tumor recurrence via postoperative photothermal therapy and bone regeneration promotion	95
An overview of substrate stiffness guided cellular response and its applications in tissue regeneration	95
Bioactive skin-mimicking hydrogel band-aids for diabetic wound healing and infectious skin incision treatment	93
Exosome-guided bone targeted delivery of Antagomir-188 as an anabolic therapy for bone loss	93
Multi-crosslinking hydrogels with robust bio-adhesion and pro-coagulant activity for first-aid hemostasis and infected wound healing	92
Macrophage membrane-coated nanocarriers Co-Modified by RVG29 and TPP improve brain neuronal mitochondria-targeting and therapeutic efficacy in Alzheimer's disease mice	91
Substrate stiffness modulates bone marrow-derived macrophage polarization through NF-κB signaling pathway	91
Biodegradable Zn–Sr alloy for bone regeneration in rat femoral condyle defect model: In vitro and in vivo studies	90
Polydopamine-mediated graphene oxide and nanohydroxyapatite-incorporated conductive scaffold with an immunomodulatory ability accelerates periodontal bone regeneration in diabetes	89
How far is Lignin from being a biomedical material?	88
Synergistic antibacterial activity of physical-chemical multi-mechanism by TiO2 nanorod arrays for safe biofilm eradication on implant	87
Titanium carbide nanosheets with defect structure for photothermal-enhanced sonodynamic therapy	87
Cartilage-targeting peptide-modified dual-drug delivery nanoplatform with NIR laser response for osteoarthritis therapy	87
Modulating macrophage activities to promote endogenous bone regeneration: Biological mechanisms and engineering approaches	87
Cellulose-based composite scaffolds for bone tissue engineering and localized drug delivery	85
Three-dimensional bioprinting of multicell-laden scaffolds containing bone morphogenic protein-4 for promoting M2 macrophage polarization and accelerating bone defect repair in diabetes mellitus	85
Carrier-free nanodrugs with efficient drug delivery and release for cancer therapy: From intrinsic physicochemical properties to external modification	84
Ca2+-supplying black phosphorus-based scaffolds fabricated with microfluidic technology for osteogenesis	81
Biological and bioinspired materials: Structure leading to functional and mechanical performance	80
Self-crosslinkable chitosan-hyaluronic acid dialdehyde nanoparticles for CD44-targeted siRNA delivery to treat bladder cancer	80
Tetrahedral framework nucleic acids-based delivery of microRNA-155 inhibits choroidal neovascularization by regulating the polarization of macrophages	79
Isolation of cabbage exosome-like nanovesicles and investigation of their biological activities in human cells	78
Microgel assembly: Fabrication, characteristics and application in tissue engineering and regenerative medicine	77
Adaptable hydrogel with reversible linkages for regenerative medicine: Dynamic mechanical microenvironment for cells	77
Biological applications of copper-containing materials	75
Synergistic anti-inflammatory and osteogenic n-HA/resveratrol/chitosan composite microspheres for osteoporotic bone regeneration	75
Hybrid gelatin/oxidized chondroitin sulfate hydrogels incorporating bioactive glass nanoparticles with enhanced mechanical properties, mineralization, and osteogenic differentiation	74
Enhancement of acellular cartilage matrix scaffold by Wharton's jelly mesenchymal stem cell-derived exosomes to promote osteochondral regeneration	74
An injectable, self-healing, electroconductive extracellular matrix-based hydrogel for enhancing tissue repair after traumatic spinal cord injury	73
Biomaterials from the sea: Future building blocks for biomedical applications	73
Cryogenic 3D printing of dual-delivery scaffolds for improved bone regeneration with enhanced vascularization	73

A bone-targeted engineered exosome platform delivering siRNA to treat osteoporosis	73
Challenges and strategies for in situ endothelialization and long-term lumen patency of vascular grafts	73
Restoration of electrical microenvironment enhances bone regeneration under diabetic conditions by modulating macrophage polarization	73
Flexible electrical stimulation device with Chitosan-Vaseline® dressing accelerates wound healing in diabetes	73