Cell Chemical Biology

Papers
(The H4-Index of Cell Chemical Biology is 45. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)
ArticleCitations
Meet the Authors: Christopher R. Mansfield and Emily R. Derbyshire158
Voices: Challenges and opportunities in regulating the immune system154
Therapeutic potential of inhibiting the PI3Kγ complex for leukemia120
Multiparatopic antibodies induce targeted downregulation of programmed death-ligand 1116
A covalent inhibitor targeting Cys16 on RhoA in colorectal cancer110
Acute pharmacological degradation of ERK5 does not inhibit cellular immune response or proliferation107
An interactive resource mapping the proteome and reactive cysteine landscape across the NCI-60 reveals cell and tissue-specific profiles106
Identification of an inhibitory pocket in falcilysin provides a new avenue for malaria drug development98
CBLs downregulation foretells T cell ubiquitination leading to autoimmunity97
2′-OH as a universal handle for studying intracellular RNAs96
A versatile residue numbering scheme for Nav and Cav channels96
Next steps for targeted protein degradation95
RENBP inhibition amplifies metabolic glycan labeling efficiency of antigen-presenting cells in vitro and in vivo95
ITK degradation to block T cell receptor signaling and overcome therapeutic resistance in T cell lymphomas94
A genome-wide CRISPR-Cas9 screen identifies CENPJ as a host regulator of altered microtubule organization during Plasmodium liver infection91
Dual-pharmacophore artezomibs hijack the Plasmodium ubiquitin-proteasome system to kill malaria parasites while overcoming drug resistance90
Advances in spatial proteomics: Mapping proteome architecture from protein complexes to subcellular localizations87
Meet the Authors: Harkamal S. Jhajj and Peter M. Tessier84
Meet the Cell Chemical Biology author and newest advisory board member: Marcus Conrad77
Engineered pistol ribozymes selectively target KRAS G12V with enhanced efficacy by capping modification74
Valence and avidity determine the agonistic activity of anti-TNFR2 nanobody fusion proteins74
Targeting the endocannabinoid-eicosanoid axis to treat pain: Promise and pitfalls74
Catalytic spike antibodies: A new paradigm in neutralization73
Peptide-mediated inhibition of the transcriptional regulator Elongin BC induces apoptosis in cancer cells71
Real-time non-invasive fluorescence imaging of gut commensal bacteria to detect dynamic changes in the microbiome of live mice70
A potent NLRP3 inhibitor effective against both MCC950-sensitive and -resistant inflammation68
Selective degradation of TBK1 uncovers mechanistic insights into blocking ccRCC progression68
Beyond antibiotic resistance: The whiB7 transcription factor coordinates an adaptive response to alanine starvation in mycobacteria65
N6-methyladenosine modification in 18S rRNA promotes tumorigenesis and chemoresistance via HSF4b/HSP90B1/mutant p53 axis64
Mechanisms by which microbiome-derived metabolites exert their impacts on neurodegeneration63
Target deconvolution with matrix-augmented pooling strategy reveals cell-specific drug-protein interactions63
Anti-tumor effect of PD-L1-targeting antagonistic aptamer-ASO delivery system with dual inhibitory function in immunotherapy59
A lipid brake on oncogenic signaling: 13-S-HODE inhibits mTOR activity58
Structural basis for NONO-specific modification by the α-chloroacetamide compound (R)-SKBG-156
A double whammy for KEAP155
Pharmacological management of disease by overcoming structural adversity54
Discovery of MARK2 as a physiological kinase for PER2 in the mammalian clock53
De novo protein assembly enables drug-controlled cellular functions51
Targeting RNA with synthetic oligonucleotides: Clinical success invites new challenges50
The art of designed coiled-coils for the regulation of mammalian cells50
BLOC-1 and BORC: Complex regulators of endolysosomal dynamics47
Metabolic tug-of-war: Microbial metabolism shapes colonization resistance against enteric pathogens47
Enabling inclusion and looking ahead45
A new chink in cancer’s armor: Unleashing cell death by selective PP5 inhibition45
Two sides of a co(i)ndensate45
PROTAC-mediated degradation of HIV-1 Nef efficiently restores cell-surface CD4 and MHC-I expression and blocks HIV-1 replication45
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