OOIR: Observatory of International Research

Papers

(The H4-Index of Cell Chemical Biology is 41. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
Acute pharmacological degradation of ERK5 does not inhibit cellular immune response or proliferation	176
Antisense-mediated senseful regulation of orchestrated metabolic response	143
New sheriff in town: Cyclic peptide inhibitors of a DUB module	134
Heterologous characterization of mechercharmycin A biosynthesis reveals alternative insights into post-translational modifications for RiPPs	113
2′-OH as a universal handle for studying intracellular RNAs	95
CBLs downregulation foretells T cell ubiquitination leading to autoimmunity	93
Generation of an anticoagulant aptamer that targets factor V/Va and disrupts the FVa-membrane interaction in normal and COVID-19 patient samples	91
Multiparatopic antibodies induce targeted downregulation of programmed death-ligand 1	91
Therapeutic potential of inhibiting the PI3Kγ complex for leukemia	76
A versatile residue numbering scheme for Nav and Cav channels	75
A genome-wide CRISPR-Cas9 screen identifies CENPJ as a host regulator of altered microtubule organization during Plasmodium liver infection	68
Voices: Challenges and opportunities in regulating the immune system	64
Development of potent and selective inhibitors targeting the papain-like protease of SARS-CoV-2	62
ITK degradation to block T cell receptor signaling and overcome therapeutic resistance in T cell lymphomas	60
Meet the Authors: Christopher R. Mansfield and Emily R. Derbyshire	59
Inhibiting a dynamic viral protease by targeting a non-catalytic cysteine	59
Dual-pharmacophore artezomibs hijack the Plasmodium ubiquitin-proteasome system to kill malaria parasites while overcoming drug resistance	59
Identification of an inhibitory pocket in falcilysin provides a new avenue for malaria drug development	59
Advances in spatial proteomics: Mapping proteome architecture from protein complexes to subcellular localizations	58
Control of topoisomerase II activity and chemotherapeutic inhibition by TCA cycle metabolites	57
Next steps for targeted protein degradation	56
Targeted degradation of transcription factors by TRAFTACs: TRAnscription Factor TArgeting Chimeras	52
FADS2-dependent fatty acid desaturation dictates cellular sensitivity to ferroptosis and permissiveness for hepatitis C virus replication	52
Target deconvolution with matrix-augmented pooling strategy reveals cell-specific drug-protein interactions	52
A complex puzzle: Regulation of SLFN12 RNase activity by phosphorylation	51

A fine-tuned azobenzene for enhanced photopharmacology in vivo	51
Peptide-mediated inhibition of the transcriptional regulator Elongin BC induces apoptosis in cancer cells	50
Beyond antibiotic resistance: The whiB7 transcription factor coordinates an adaptive response to alanine starvation in mycobacteria	50
Mechanisms by which microbiome-derived metabolites exert their impacts on neurodegeneration	50
A synthetic RNA-based biosensor for fructose-1,6-bisphosphate that reports glycolytic flux	48
Catalytic spike antibodies: A new paradigm in neutralization	47
Meet the Authors: Harkamal S. Jhajj and Peter M. Tessier	46
Real-time non-invasive fluorescence imaging of gut commensal bacteria to detect dynamic changes in the microbiome of live mice	46
Scribble sub-cellular localization modulates recruitment of YES1 to regulate YAP1 phosphorylation	46
N6-methyladenosine modification in 18S rRNA promotes tumorigenesis and chemoresistance via HSF4b/HSP90B1/mutant p53 axis	45
PALP: A rapid imaging technique for stratifying ferroptosis sensitivity in normal and tumor tissues in situ	45
Anti-tumor effect of PD-L1-targeting antagonistic aptamer-ASO delivery system with dual inhibitory function in immunotherapy	45
Peripherally active dextromethorphan derivatives lower blood glucose levels by targeting pancreatic islets	44
The role of reversible and irreversible covalent chemistry in targeted protein degradation	44
A biaryl-linked tripeptide from Planomonospora reveals a widespread class of minimal RiPP gene clusters	41
Probing the binding of interleukin-23 to individual receptor components and the IL-23 heteromeric receptor complex in living cells using NanoBRET	41
Visualizing Staphylococcus aureus pathogenic membrane modification within the host infection environment by multimodal imaging mass spectrometry	41