OOIR: Observatory of International Research

Papers

(The H4-Index of Cell Chemical Biology is 40. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)

Article	Citations
Antisense-mediated senseful regulation of orchestrated metabolic response	108
New sheriff in town: Cyclic peptide inhibitors of a DUB module	93
CBLs downregulation foretells T cell ubiquitination leading to autoimmunity	76
Generation of an anticoagulant aptamer that targets factor V/Va and disrupts the FVa-membrane interaction in normal and COVID-19 patient samples	71
Therapeutic potential of inhibiting the PI3Kγ complex for leukemia	69
Multiparatopic antibodies induce targeted downregulation of programmed death-ligand 1	67
A versatile residue numbering scheme for Nav and Cav channels	65
ITK degradation to block T cell receptor signaling and overcome therapeutic resistance in T cell lymphomas	65
Control of topoisomerase II activity and chemotherapeutic inhibition by TCA cycle metabolites	63
Acute pharmacological degradation of ERK5 does not inhibit cellular immune response or proliferation	63
Meet the Authors: Christopher R. Mansfield and Emily R. Derbyshire	61
FADS2-dependent fatty acid desaturation dictates cellular sensitivity to ferroptosis and permissiveness for hepatitis C virus replication	59
Voices: Challenges and opportunities in regulating the immune system	59
Dual-pharmacophore artezomibs hijack the Plasmodium ubiquitin-proteasome system to kill malaria parasites while overcoming drug resistance	58
Heterologous characterization of mechercharmycin A biosynthesis reveals alternative insights into post-translational modifications for RiPPs	58
Inhibiting a dynamic viral protease by targeting a non-catalytic cysteine	57
A genome-wide CRISPR-Cas9 screen identifies CENPJ as a host regulator of altered microtubule organization during Plasmodium liver infection	55
Advances in spatial proteomics: Mapping proteome architecture from protein complexes to subcellular localizations	55
Identification of an inhibitory pocket in falcilysin provides a new avenue for malaria drug development	55
Next steps for targeted protein degradation	54
2′-OH as a universal handle for studying intracellular RNAs	54
Scribble sub-cellular localization modulates recruitment of YES1 to regulate YAP1 phosphorylation	53
Target deconvolution with matrix-augmented pooling strategy reveals cell-specific drug-protein interactions	51
Peptide-mediated inhibition of the transcriptional regulator Elongin BC induces apoptosis in cancer cells	51
Catalytic spike antibodies: A new paradigm in neutralization	49

Beyond antibiotic resistance: The whiB7 transcription factor coordinates an adaptive response to alanine starvation in mycobacteria	48
Meet the Cell Chemical Biology author and newest advisory board member: Marcus Conrad	47
Meet the Authors: Harkamal S. Jhajj and Peter M. Tessier	47
Mechanisms by which microbiome-derived metabolites exert their impacts on neurodegeneration	47
Real-time non-invasive fluorescence imaging of gut commensal bacteria to detect dynamic changes in the microbiome of live mice	46
A complex puzzle: Regulation of SLFN12 RNase activity by phosphorylation	45
Anti-tumor effect of PD-L1-targeting antagonistic aptamer-ASO delivery system with dual inhibitory function in immunotherapy	45
N6-methyladenosine modification in 18S rRNA promotes tumorigenesis and chemoresistance via HSF4b/HSP90B1/mutant p53 axis	44
A fine-tuned azobenzene for enhanced photopharmacology in vivo	43
A synthetic RNA-based biosensor for fructose-1,6-bisphosphate that reports glycolytic flux	41
PALP: A rapid imaging technique for stratifying ferroptosis sensitivity in normal and tumor tissues in situ	41
Probing the binding of interleukin-23 to individual receptor components and the IL-23 heteromeric receptor complex in living cells using NanoBRET	40
PROTAC-mediated degradation of HIV-1 Nef efficiently restores cell-surface CD4 and MHC-I expression and blocks HIV-1 replication	40
Peripherally active dextromethorphan derivatives lower blood glucose levels by targeting pancreatic islets	40
Pharmacological management of disease by overcoming structural adversity	40