OOIR: Observatory of International Research

Papers

(The H4-Index of Cell Systems is 35. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
Evaluation of Peterson et al.: MAPK cascades don’t work in silos: MAP3K cross-activation of MAPKs and the effect of crosstalk on cellular responses	425
Statistical modeling and analysis of cell counts from multiplexed imaging data	210
Engineering functional materials through bacteria-assisted living grafting	132
A digital CRISPR-dCas9-based gene remodeling biocomputer programmed by dietary compounds in mammals	128
Positional influence on cellular transcriptional identity revealed through spatially segmented single-cell transcriptomics	117
A combinatorial transcription factor screening platform for immune cell reprogramming	116
Probing enzyme-dependent pseudouridylation using direct RNA sequencing to assess epitranscriptome plasticity in a neuronal cell line	112
Leveraging attention-based deep multiple instance and multiple task learning for improved neoepitope identification	99
Decoding the role of the arginine dihydrolase pathway in shaping human gut community assembly and health-relevant metabolites	91
A data-driven modeling framework for mapping genotypes to synthetic microbial community functions	88
Pitfalls of genotyping microbial communities with rapidly growing genome collections	67
A framework for ultra-low-input spatial tissue proteomics	61
How can the protein design community best support biologists who want to harness AI tools for protein structure prediction and design?	60
Context-informed subgraph foundation models enable interpretable protein-function prediction	57
Signaling and transcriptional dynamics underlying early adaptation to oncogenic BRAF inhibition	55
What are the current bottlenecks in developing and applying CRISPR technologies?	53
Diclofenac and acetaminophen dim the acute-phase response but amplify expression of the iron regulator hepcidin in liver cancer cells	53
Evolutionary paths that link orthogonal pairs of binding proteins	51
Brain dynamics supported by a hierarchy of complex correlation patterns defining a robust functional architecture	49
Identifying maximally informative signal-aware representations of single-cell data using the information bottleneck	49
Modeling collective cell behavior in cancer: Perspectives from an interdisciplinary conversation	48
Emerging approaches for characterizing spatial and temporal dynamics of pathogen-induced organelle remodeling	46
Integrative, high-resolution analysis of single-cell gene expression across experimental conditions with PARAFAC2-RISE	45
From modality-specific to compositional foundation models for cell biology	45
Accurate single-molecule spot detection for image-based spatial transcriptomics with weakly supervised deep learning	44

Allelic correlation is a marker of trade-offs between barriers to transmission of expression variability and signal responsiveness in genetic networks	43
A bipartite function of ESRRB can integrate signaling over time to balance self-renewal and differentiation	43
Quantifying protein unfolding kinetics with a high-throughput microfluidic platform	43
Causal gene regulatory analysis with RNA velocity reveals an interplay between slow and fast transcription factors	40
How can concepts from ecology enable insights about cellular communities?	39
The electrostatic landscape of MHC-peptide binding revealed using inception networks	37
Rugged fitness landscapes minimize promiscuity in the evolution of transcriptional repressors	36
Modeling elucidates context dependence in adipose regulation	36
Evaluating predictive patterns of antigen-specific B cells by single-cell transcriptome and antibody repertoire sequencing	36
Translation elongation as a rate-limiting step of protein production	35