Communications Biology

Papers
(The TQCC of Communications Biology is 12. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-10-01 to 2024-10-01.)
ArticleCitations
DeepEMhancer: a deep learning solution for cryo-EM volume post-processing715
A comprehensive review on plasmonic-based biosensors used in viral diagnostics308
Single-cell and spatial transcriptomics enables probabilistic inference of cell type topography295
Ionization and structural properties of mRNA lipid nanoparticles influence expression in intramuscular and intravascular administration194
Role of sleep deprivation in immune-related disease risk and outcomes185
Second-generation lung-on-a-chip with an array of stretchable alveoli made with a biological membrane181
Mapping the immune environment in clear cell renal carcinoma by single-cell genomics179
Towards organoid culture without Matrigel173
Activation of mitochondrial TUFM ameliorates metabolic dysregulation through coordinating autophagy induction169
Identification of 3-chymotrypsin like protease (3CLPro) inhibitors as potential anti-SARS-CoV-2 agents165
Amplification-free RNA detection with CRISPR–Cas13142
SARS-CoV-2 infection induces a pro-inflammatory cytokine response through cGAS-STING and NF-κB141
Identification of SARS-CoV-2 inhibitors targeting Mpro and PLpro using in-cell-protease assay140
The antimicrobial potential of cannabidiol140
NetTCR-2.0 enables accurate prediction of TCR-peptide binding by using paired TCRα and β sequence data133
The genetic architecture of appendicular lean mass characterized by association analysis in the UK Biobank study129
Brains and algorithms partially converge in natural language processing128
Deep ocean metagenomes provide insight into the metabolic architecture of bathypelagic microbial communities128
Climate-change-driven growth decline of European beech forests124
Simple and effective serum-free medium for sustained expansion of bovine satellite cells for cell cultured meat122
Human ACE2 receptor polymorphisms and altered susceptibility to SARS-CoV-2117
Fatty-acid-induced FABP5/HIF-1 reprograms lipid metabolism and enhances the proliferation of liver cancer cells114
Analysis of SARS-CoV-2 mutations in the United States suggests presence of four substrains and novel variants111
Telomere-to-telomere gapless chromosomes of banana using nanopore sequencing105
Genomic and transcriptomic variation defines the chromosome-scale assembly of Haemonchus contortus, a model gastrointestinal worm104
Inhibition of the CCL2 receptor, CCR2, enhances tumor response to immune checkpoint therapy100
Accelerating antibiotic discovery through artificial intelligence100
Large-scale integration of single-cell transcriptomic data captures transitional progenitor states in mouse skeletal muscle regeneration99
Comparative ACE2 variation and primate COVID-19 risk98
Single-cell analysis supports a luminal-neuroendocrine transdifferentiation in human prostate cancer98
Integration of substrate- and flow-derived stresses in endothelial cell mechanobiology97
Temporal association between human upper respiratory and gut bacterial microbiomes during the course of COVID-19 in adults95
Molecular basis for the disruption of Keap1–Nrf2 interaction via Hinge & Latch mechanism95
Prioritization of candidate causal genes for asthma in susceptibility loci derived from UK Biobank94
A genome-wide meta-analysis yields 46 new loci associating with biomarkers of iron homeostasis93
Human ACE2 peptide-mimics block SARS-CoV-2 pulmonary cells infection93
Cryo-EM structure of type 1 IP3R channel in a lipid bilayer90
From whole-mount to single-cell spatial assessment of gene expression in 3D90
Sand flies: Basic information on the vectors of leishmaniasis and their interactions with Leishmania parasites88
The brain and its time: intrinsic neural timescales are key for input processing88
ExoSTING, an extracellular vesicle loaded with STING agonists, promotes tumor immune surveillance88
PD-1 derived CA-170 is an oral immune checkpoint inhibitor that exhibits preclinical anti-tumor efficacy87
SARS-CoV-2 specific antibody and neutralization assays reveal the wide range of the humoral immune response to virus86
ImmuneBuilder: Deep-Learning models for predicting the structures of immune proteins85
Multiple impacts of microplastics can threaten marine habitat-forming species83
Exploring the evidence for epigenetic regulation of environmental influences on child health across generations81
Microglial metabolism is a pivotal factor in sexual dimorphism in Alzheimer’s disease80
A framework for identifying the recent origins of mobile antibiotic resistance genes80
Climate change threatens Chinook salmon throughout their life cycle79
Tipiracil binds to uridine site and inhibits Nsp15 endoribonuclease NendoU from SARS-CoV-277
Type I toxin-antitoxin systems contribute to the maintenance of mobile genetic elements in Clostridioides difficile77
Features and applications of haplotypes in crop breeding76
Optogenetic therapy: high spatiotemporal resolution and pattern discrimination compatible with vision restoration in non-human primates76
Temporal hierarchy of intrinsic neural timescales converges with spatial core-periphery organization76
A haplotype-led approach to increase the precision of wheat breeding76
Cyanobacterial blooms contribute to the diversity of antibiotic-resistance genes in aquatic ecosystems75
A novel canine reference genome resolves genomic architecture and uncovers transcript complexity75
When dormancy fuels tumour relapse73
More than half of data deficient species predicted to be threatened by extinction72
High frequency acoustic cell stimulation promotes exosome generation regulated by a calcium-dependent mechanism72
Wnt signaling in lung development, regeneration, and disease progression71
IFN signaling and neutrophil degranulation transcriptional signatures are induced during SARS-CoV-2 infection71
NEBULA is a fast negative binomial mixed model for differential or co-expression analysis of large-scale multi-subject single-cell data71
The multiple mechanisms of MCL1 in the regulation of cell fate69
Genome-resolved metagenomics suggests a mutualistic relationship between Mycoplasma and salmonid hosts69
Tumor microbiome contributes to an aggressive phenotype in the basal-like subtype of pancreatic cancer69
Design and optimisation of dendrimer-conjugated Bcl-2/xL inhibitor, AZD0466, with improved therapeutic index for cancer therapy68
A combined approach for single-cell mRNA and intracellular protein expression analysis68
Gut microbiome diversity is an independent predictor of survival in cervical cancer patients receiving chemoradiation68
Large-scale shift in the structure of a kelp forest ecosystem co-occurs with an epizootic and marine heatwave67
Surfactant-assisted one-pot sample preparation for label-free single-cell proteomics67
The gut mycobiome of healthy mice is shaped by the environment and correlates with metabolic outcomes in response to diet66
Biomolecular condensates as arbiters of biochemical reactions inside the nucleus66
Gut mycobiota alterations in patients with COVID-19 and H1N1 infections and their associations with clinical features65
Bacterial diets differentially alter lifespan and healthspan trajectories in C. elegans64
High resolution DNA barcode library for European butterflies reveals continental patterns of mitochondrial genetic diversity63
Detritivore conversion of litter into faeces accelerates organic matter turnover63
Epigenetic landscape of pancreatic neuroendocrine tumours reveals distinct cells of origin and means of tumour progression62
Topologically associating domain boundaries are required for normal genome function62
Biocompatible nucleus-targeted graphene quantum dots for selective killing of cancer cells via DNA damage61
A high-throughput Galectin-9 imaging assay for quantifying nanoparticle uptake, endosomal escape and functional RNA delivery60
Immunological considerations and challenges for regenerative cellular therapies60
Author Correction: Cycloalkane-modified amphiphilic polymers provide direct extraction of membrane proteins for CryoEM analysis59
Full structural ensembles of intrinsically disordered proteins from unbiased molecular dynamics simulations59
Tet2 at the interface between cancer and immunity59
Decoding the transcriptome of calcified atherosclerotic plaque at single-cell resolution58
Mash-based analyses of Escherichia coli genomes reveal 14 distinct phylogroups58
SARS-CoV-2 Omicron variant is attenuated for replication in a polarized human lung epithelial cell model57
Deciphering tissue structure and function using spatial transcriptomics57
Real-time synthesis of imagined speech processes from minimally invasive recordings of neural activity57
Metagenome-assembled genomes and gene catalog from the chicken gut microbiome aid in deciphering antibiotic resistomes57
Identifying behavioral structure from deep variational embeddings of animal motion56
Clinical evolution of ST11 carbapenem resistant and hypervirulent Klebsiella pneumoniae56
Global patterns in genomic diversity underpinning the evolution of insecticide resistance in the aphid crop pest Myzus persicae55
Prediction of 3D Cardiovascular hemodynamics before and after coronary artery bypass surgery via deep learning55
BMP-2 and VEGF-A modRNAs in collagen scaffold synergistically drive bone repair through osteogenic and angiogenic pathways54
Stony coral tissue loss disease decimated Caribbean coral populations and reshaped reef functionality54
Comparative analysis of 1152 African-American and European-American men with prostate cancer identifies distinct genomic and immunological differences53
A large-scale genome-wide cross-trait analysis reveals shared genetic architecture between Alzheimer’s disease and gastrointestinal tract disorders53
Inside-out chicken enteroids with leukocyte component as a model to study host–pathogen interactions53
Discovery of stripe rust resistance with incomplete dominance in wild emmer wheat using bulked segregant analysis sequencing52
The structural basis of function and regulation of neuronal cotransporters NKCC1 and KCC252
Large genome-wide association study identifies three novel risk variants for restless legs syndrome52
High stability and metabolic capacity of bacterial community promote the rapid reduction of easily decomposing carbon in soil52
Whole-genome sequence analysis unveils different origins of European and Asiatic mouflon and domestication-related genes in sheep52
Optimizing spectral quality with quantum dots to enhance crop yield in controlled environments52
Genome-wide analysis of DNA G-quadruplex motifs across 37 species provides insights into G4 evolution51
A multi-ethnic genome-wide association study implicates collagen matrix integrity and cell differentiation pathways in keratoconus51
High-resolution cryo-EM structure of photosystem II reveals damage from high-dose electron beams51
Passive eDNA collection enhances aquatic biodiversity analysis51
Genome editing in plants using CRISPR type I-D nuclease51
Wuschel2 enables highly efficient CRISPR/Cas-targeted genome editing during rapid de novo shoot regeneration in sorghum51
Cell-autonomous immune gene expression is repressed in pulmonary neuroendocrine cells and small cell lung cancer51
Restoring indigenous names in taxonomy51
DNA–protein crosslink proteases in genome stability50
AlphaFold2 reveals commonalities and novelties in protein structure space for 21 model organisms50
The interplay between membrane topology and mechanical forces in regulating T cell receptor activity50
Loss of consciousness reduces the stability of brain hubs and the heterogeneity of brain dynamics49
Integrating cell morphology with gene expression and chemical structure to aid mitochondrial toxicity detection49
Menstrual flow as a non-invasive source of endometrial organoids49
The lexicon of antimicrobial peptides: a complete set of arginine and tryptophan sequences49
Insights into the genomic evolution of insects from cricket genomes49
Molecular and phenotypic analysis of rodent models reveals conserved and species-specific modulators of human sarcopenia49
Co-delivery of resolvin D1 and antibiotics with nanovesicles to lungs resolves inflammation and clears bacteria in mice49
Sulforaphane exhibits antiviral activity against pandemic SARS-CoV-2 and seasonal HCoV-OC43 coronaviruses in vitro and in mice49
Wolfberry genomes and the evolution of Lycium (Solanaceae)49
Volatile organic compound patterns predict fungal trophic mode and lifestyle49
Secreted midbody remnants are a class of extracellular vesicles molecularly distinct from exosomes and microparticles48
Adaptation by copy number variation increases insecticide resistance in the fall armyworm48
The kinetics of humoral response and its relationship with the disease severity in COVID-1948
Ten emerging SARS-CoV-2 spike variants exhibit variable infectivity, animal tropism, and antibody neutralization48
Spatiotemporal identification of druggable binding sites using deep learning48
Predicting clinical resistance prevalence using sewage metagenomic data47
DeepBacs for multi-task bacterial image analysis using open-source deep learning approaches47
Dynamic relationships between spontaneous and evoked electrophysiological activity47
Climate and seasonality drive the richness and composition of tropical fungal endophytes at a landscape scale47
Structural definition of a pan-sarbecovirus neutralizing epitope on the spike S2 subunit47
The surprising role of the default mode network in naturalistic perception47
Engineering of ultraID, a compact and hyperactive enzyme for proximity-dependent biotinylation in living cells46
Identification of a pathway for electron uptake in Shewanella oneidensis46
Annotation of chromatin states in 66 complete mouse epigenomes during development46
Single-cell transcriptomics following ischemic injury identifies a role for B2M in cardiac repair46
Cell response analysis in SARS-CoV-2 infected bronchial organoids46
Fast automated detection of COVID-19 from medical images using convolutional neural networks46
Integrated molecular characterisation of the MAPK pathways in human cancers reveals pharmacologically vulnerable mutations and gene dependencies45
An alternative pathway for membrane protein biogenesis at the endoplasmic reticulum45
Droplet-based microfluidic platform for high-throughput screening of Streptomyces45
SARS-CoV-2 spike opening dynamics and energetics reveal the individual roles of glycans and their collective impact45
Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations44
A modular two yeast species secretion system for the production and preparative application of unspecific peroxygenases44
Real-time structure search and structure classification for AlphaFold protein models44
Reduced C9orf72 function leads to defective synaptic vesicle release and neuromuscular dysfunction in zebrafish44
Photoreceptor metabolic reprogramming: current understanding and therapeutic implications44
Bridgehead effect and multiple introductions shape the global invasion history of a termite44
A global microbiome survey of vineyard soils highlights the microbial dimension of viticultural terroirs43
Engineered marble-like bovine fat tissue for cultured meat43
OxPhos defects cause hypermetabolism and reduce lifespan in cells and in patients with mitochondrial diseases43
A generic approach to study the kinetics of liquid–liquid phase separation under near-native conditions43
The cancer glycocalyx mediates intravascular adhesion and extravasation during metastatic dissemination43
A chromosome-level genome sequence of Chrysanthemum seticuspe, a model species for hexaploid cultivated chrysanthemum43
A single day of TGF-β1 exposure activates chondrogenic and hypertrophic differentiation pathways in bone marrow-derived stromal cells43
Crowding-induced opening of the mechanosensitive Piezo1 channel in silico43
A deeper look at carrier proteome effects for single-cell proteomics43
3D tumor spheroid microarray for high-throughput, high-content natural killer cell-mediated cytotoxicity43
Phylogenetic inference enables reconstruction of a long-overlooked outbreak of almond leaf scorch disease (Xylella fastidiosa) in Europe42
Impact of sleep duration on executive function and brain structure42
Cancer-associated hypersialylated MUC1 drives the differentiation of human monocytes into macrophages with a pathogenic phenotype42
Characterization of phage resistance and phages capable of intestinal decolonization of carbapenem-resistant Klebsiella pneumoniae in mice42
Dorsal and ventral striatal functional connectivity shifts play a potential role in internet gaming disorder42
Targeted intracellular degradation of SARS-CoV-2 via computationally optimized peptide fusions42
Structural basis of coronavirus E protein interactions with human PALS1 PDZ domain42
Elevated microglial oxidative phosphorylation and phagocytosis stimulate post-stroke brain remodeling and cognitive function recovery in mice42
Long-term field-realistic exposure to a next-generation pesticide, flupyradifurone, impairs honey bee behaviour and survival41
Global population genomic signature of Spodoptera frugiperda (fall armyworm) supports complex introduction events across the Old World41
Breakdown of supersaturation barrier links protein folding to amyloid formation41
Genome-wide association studies and heritability analysis reveal the involvement of host genetics in the Japanese gut microbiota41
A pictorial account of the human embryonic heart between 3.5 and 8 weeks of development41
NAD+/NADH redox alterations reconfigure metabolism and rejuvenate senescent human mesenchymal stem cells in vitro41
Simple sequence repeats drive genome plasticity and promote adaptive evolution in penaeid shrimp41
Towards a comprehensive evaluation of dimension reduction methods for transcriptomic data visualization41
LPMO-oxidized cellulose oligosaccharides evoke immunity in Arabidopsis conferring resistance towards necrotrophic fungus B. cinerea41
Multivalent nanoparticle-based vaccines protect hamsters against SARS-CoV-2 after a single immunization40
Moisture modulates soil reservoirs of active DNA and RNA viruses40
Organisational and neuromodulatory underpinnings of structural-functional connectivity decoupling in patients with Parkinson’s disease40
Chemokine mediated signalling within arteries promotes vascular smooth muscle cell recruitment40
Multi-species and multi-tissue methylation clocks for age estimation in toothed whales and dolphins40
Development of deep learning algorithms for predicting blastocyst formation and quality by time-lapse monitoring40
Osteopontin binds ICOSL promoting tumor metastasis40
Immunoreactive peptide maps of SARS-CoV-240
Three-dimensional spatial transcriptomics uncovers cell type localizations in the human rheumatoid arthritis synovium40
Human TRPC5 structures reveal interaction of a xanthine-based TRPC1/4/5 inhibitor with a conserved lipid binding site40
Non-linear machine learning models incorporating SNPs and PRS improve polygenic prediction in diverse human populations40
Matrigel 3D bioprinting of contractile human skeletal muscle models recapitulating exercise and pharmacological responses40
R–R–T (resistance–resilience–transformation) typology reveals differential conservation approaches across ecosystems and time40
Distortion of the bilayer and dynamics of the BAM complex in lipid nanodiscs39
p38-MAPK-mediated translation regulation during early blastocyst development is required for primitive endoderm differentiation in mice39
Phenotypic analysis of catastrophic childhood epilepsy genes39
The C-terminal tail of α-synuclein protects against aggregate replication but is critical for oligomerization39
Outer-membrane-acting peptides and lipid II-targeting antibiotics cooperatively kill Gram-negative pathogens39
Structural insights into photoactivation of plant Cryptochrome-239
A reference-grade genome identifies salt-tolerance genes from the salt-secreting mangrove species Avicennia marina39
Antibodies exhibit multiple paratope states influencing VH–VL domain orientations39
Live cell dynamics of production, explosive release and killing activity of phage tail-like weapons for Pseudomonas kin exclusion39
Methamphetamine induces cardiomyopathy by Sigmar1 inhibition-dependent impairment of mitochondrial dynamics and function39
Multiple memories can be simultaneously reactivated during sleep as effectively as a single memory38
NTRK kinase domain mutations in cancer variably impact sensitivity to type I and type II inhibitors38
The anesthetic sevoflurane induces tau trafficking from neurons to microglia38
Enhancing carbohydrate repartitioning into lipid and carotenoid by disruption of microalgae starch debranching enzyme38
Plants grown in Apollo lunar regolith present stress-associated transcriptomes that inform prospects for lunar exploration38
An investigation of the cognitive and neural correlates of semantic memory search related to creative ability38
Artemisinin resistance in the malaria parasite, Plasmodium falciparum, originates from its initial transcriptional response38
Genome-wide bioinformatic analyses predict key host and viral factors in SARS-CoV-2 pathogenesis38
Causal contributors to tissue stiffness and clinical relevance in urology38
Human encroachment into wildlife gut microbiomes38
Sedimentary DNA tracks decadal-centennial changes in fish abundance38
Combination of antiviral drugs inhibits SARS-CoV-2 polymerase and exonuclease and demonstrates COVID-19 therapeutic potential in viral cell culture38
Evidence for continuity of interstitial spaces across tissue and organ boundaries in humans37
Bovine host genome acts on rumen microbiome function linked to methane emissions37
The metabolic network of the last bacterial common ancestor37
The hierarchy of root branching order determines bacterial composition, microbial carrying capacity and microbial filtering37
Hyperthermophilic methanogenic archaea act as high-pressure CH4 cell factories37
Post-correlation on-lamella cryo-CLEM reveals the membrane architecture of lamellar bodies37
The ribosome modulates folding inside the ribosomal exit tunnel37
Phytoplankton responses to changing temperature and nutrient availability are consistent across the tropical and subtropical Atlantic37
Partial inhibition of mitochondrial complex I ameliorates Alzheimer’s disease pathology and cognition in APP/PS1 female mice37
High-frequency burst spiking in layer 5 thick-tufted pyramids of rat primary somatosensory cortex encodes exploratory touch37
Genomic profiling reveals heterogeneous populations of ductal carcinoma in situ of the breast37
A synthetic RNA editing factor edits its target site in chloroplasts and bacteria37
Characterisation of PDGF-BB:PDGFRβ signalling pathways in human brain pericytes: evidence of disruption in Alzheimer’s disease36
Identification of a missense variant in SPDL1 associated with idiopathic pulmonary fibrosis36
Single cell analysis of spondyloarthritis regulatory T cells identifies distinct synovial gene expression patterns and clonal fates36
Intracellular thermometry uncovers spontaneous thermogenesis and associated thermal signaling36
Light environment drives evolution of color vision genes in butterflies and moths36
Decorin-mediated suppression of tumorigenesis, invasion, and metastasis in inflammatory breast cancer36
Fluorescence lifetime DNA-PAINT for multiplexed super-resolution imaging of cells36
Time-resolved structure-function coupling in brain networks36
Squalenoyl siRNA PMP22 nanoparticles are effective in treating mouse models of Charcot-Marie-Tooth disease type 1 A36
Automated amplification-free digital RNA detection platform for rapid and sensitive SARS-CoV-2 diagnosis36
Microbial dysbiosis reflects disease resistance in diverse coral species35
High concentrations of dissolved biogenic methane associated with cyanobacterial blooms in East African lake surface water35
Claudin-2 promotes colorectal cancer liver metastasis and is a biomarker of the replacement type growth pattern35
Accessory proteins of the RAS-MAPK pathway: moving from the side line to the front line35
IL36 is a critical upstream amplifier of neutrophilic lung inflammation in mice35
Active maintenance of proton motive force mediates starvation-induced bacterial antibiotic tolerance in Escherichia coli35
Pharmacological inactivation of the prion protein by targeting a folding intermediate35
Components of a Neanderthal gut microbiome recovered from fecal sediments from El Salt35
Sensitive quantification of carbon monoxide in vivo reveals a protective role of circulating hemoglobin in CO intoxication35
Environmental DNA provides higher resolution assessment of riverine biodiversity and ecosystem function via spatio-temporal nestedness and turnover partitioning35
SARS-CoV-2 ORF6 disrupts nucleocytoplasmic trafficking to advance viral replication35
Preclinical validation of a live attenuated dermotropic Leishmania vaccine against vector transmitted fatal visceral leishmaniasis35
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