Human Reproduction Open

Papers
(The median citation count of Human Reproduction Open is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)
ArticleCitations
Outcome reporting across randomized controlled trials evaluating potential treatments for male infertility: a systematic review978
Pregnancy and perinatal outcomes after modified natural cycle-frozen embryo transfers according to size of the dominant follicle on the hCG trigger day285
Risk factors associated with monozygotic twinning in offspring conceived by assisted reproductive technology160
Gamete donation: anti-anonymity does not equate to anti-donation158
Defending access to reproductive health information151
The microbiome in reproductive health: protocol for a systems biology approach using a prospective, observational study design111
Extracellular vesicles secreted by human aneuploid embryos present a distinct transcriptomic profile and upregulate MUC1 transcription in decidualised endometrial stromal cells75
In infertile women with subclinical hypothyroidism, with or without thyroid peroxidase antibodies, serum TSH during pregnancy follows preconception values and thyroid hormones remain stable71
A comprehensive study of common and rare genetic variants in spermatogenesis-related loci identifies new risk factors for idiopathic severe spermatogenic failure50
Spermatocyte injection into meiotic oocytes rescues diplotene, but not pachytene, arrest in azoospermic mutant mice48
Blastocyst telomere length predicts successful implantation after frozen-thawed embryo transfer48
Biallelic mutations in RNA-binding protein ADAD2 cause spermiogenic failure and non-obstructive azoospermia in humans47
Birth outcomes in mothers with hypertensive disorders and polycystic ovary syndrome: a population-based cohort study43
Current global status of male reproductive health42
Health-related quality of life in women with endometriosis: psychometric validation of the Endometriosis Health Profile 30 questionnaire using confirmatory factor analysis42
Ovarian ferroptosis induced by androgen is involved in pathogenesis of PCOS31
Effects of different embryo culture media on birthweight following assisted reproductive technology28
Multi-omics analysis of uterine fluid extracellular vesicles reveals a resemblance with endometrial tissue across the menstrual cycle: biological and translational insights27
The role of endometrial B cells in normal endometrium and benign female reproductive pathologies: a systematic review27
Why the hypothesis of embryo selection in IVF/ICSI must finally be reconsidered27
Independent factors associated with intracytoplasmic sperm injection outcomes in patients with complete azoospermia factor c microdeletions26
Phytochemical consumption and the risk of teratozoospermia: findings from a hospital-based case–control study in China25
Effects of maternal poor ovarian response on the reproductive endocrine profiles of the next generation: a prospective cohort study in China25
Automatic identification of human spermatozoa with zona pellucida-binding capability using deep learning21
Protocol for developing a core outcome set for male infertility research: an international consensus development study19
Reproductive factors and their association with physical and comprehensive frailty in middle-aged and older women: a large-scale population-based study19
Bone mineralization in children aged 7–10 years born after ART with frozen and fresh embryo transfer18
Double vitrification and warming does not compromise the chance of live birth—a potential invalid conclusion18
Human endometrial cell-type-specific RNA sequencing provides new insights into the embryo–endometrium interplay18
No difference in cumulative live birth rates between cleavage versus blastocyst transfer in patients with four or fewer zygotes: results from a retrospective study18
Correction to: Fresh and cumulative live birth rates in mild versus conventional stimulation for IVF cycles in poor ovarian responders: a systematic review and meta-analysis18
The thicker the endometrium, the better the neonatal outcomes?17
Effect of pubertal induction with combined gonadotropin therapy on testes development and spermatogenesis in males with gonadotropin deficiency: a cohort study16
Biopsy vs comprehensive embryo/blastocyst analysis: a closer look at embryonic chromosome evaluation15
Bisphenol-A disturbs hormonal levels and testis mitochondrial activity, reducing male fertility15
Low ovarian reserve and risk of miscarriage in pregnancies derived from assisted reproductive technology15
Human umbilical cord platelet-rich plasma to treat endometrial pathologies: methodology, composition and pre-clinical models15
Effects of ovarian stimulation on embryo euploidy: an analysis of 12 874 oocytes and 3106 blastocysts in cycles with preimplantation genetic testing for monogenic disorders15
Return rates for the use of ovarian tissue cryopreserved prior to gonadotoxic treatment as fertility preservation: a systematic review15
ART in Europe, 2018: results generated from European registries by ESHRE14
Ovarian reserve in reproductive-aged patients with cancer before gonadotoxic treatment: a systematic review and meta-analysis13
Development of deep pelvic endometriosis following acute haemoperitoneum: a prospective ultrasound study13
Unveiling the paradox—low ovarian reserve in ART pregnancies and the hidden opportunities in research12
Use of mesenchymal stem cells to enhance or restore fertility potential: a systematic review of available experimental strategies12
Hiding in plain sight12
The impact of small and asymptomatic intramural and subserosal fibroids on female fertility: a case–control study12
Reply: Artificial intelligence as a door opener for a new era of human reproduction12
ESHRE survey results and good practice recommendations on managing chromosomal mosaicism12
Unmasking the risk: clinical trials versus real-world evidence on dydrogesterone and birth defects11
Lateral distribution of endometriotic lesions: the anatomical recesses hypothesis. A systematic review and meta-analysis11
Speaking up for the safety of the children following frozen embryo transfer11
Summer is not associated with higher live birth rates in fresh IVF/ICSI cycles: a population-based nationwide registry study11
Women’s reproductive span: a systematic scoping review11
The lack of evidence behind over-the-counter antioxidant supplements for male fertility patients: a scoping review11
Diagnosing chronic endometritis: when simplification fails to clarify11
Birth defects reporting and the use of dydrogesterone: a disproportionality analysis from the World Health Organization pharmacovigilance database (VigiBase)11
Reply: Emerging evidence of endometrial compaction in predicting ART outcomes11
The forgotten group of donor-conceived persons11
Obstetric and perinatal outcomes in women with previous breast cancer: a nationwide study of singleton births 1973–201711
The risk of asthma in singletons conceived by ART: a retrospective cohort study10
Correction to: Birth defects reporting and the use of dydrogesterone: a disproportionality analysis from the World Health Organization pharmacovigilance database (VigiBase)10
Bi-allelic variants in DNAH3 cause male infertility with asthenoteratozoospermia in humans and mice10
The impact of in utero exposure to cancer treatments on foetal reproductive development and future fertility: a systematic review10
The effect of frozen embryo transfer regimen on the association between serum progesterone and live birth: a multicentre prospective cohort study (ProFET)10
Improving sperm selection strategies for assisted reproduction through closing the knowledge gap in sperm maturation mechanics9
Technical specificities of the study of the mitochondrial genome9
No evidence of a causal relationship between miscarriage and 25-hydroxyvitamin D: a Mendelian randomization study9
Reply to: Anti-anonymity should not be taken more seriously than other positions on gamete donation9
Fertility preservation in women with endometriosis9
Genetic architecture of congenital hypogonadotropic hypogonadism: insights from analysis of a Portuguese cohort9
Women may not benefit from repeated frozen embryo transfers: a retrospective analysis of the cumulative live birth rate of 43 972 women9
Fertility preservation in adult male patients with cancer: a systematic review and meta-analysis9
ESHRE PGT Consortium data collection XXI: PGT analyses in 20188
Paternal age and neonatal health: unraveling epigenetic pathways8
Reply: Fetal safety of dydrogesterone: clarifying the role of pharmacovigilance8
Reliability and validity of the PHQ-8 in first-time mothers who used assisted reproductive technology8
mtDNA content in cumulus cells does not predict development to blastocyst or implantation8
Rapamycin improves the developmental competence of human oocytes by alleviating DNA damage during IVM8
Study protocol for a Developmental Epidemiological Study of Children born through Reproductive Technologies (DESCRT)8
Exploration of decision-making regarding the transfer of mosaic embryos following preimplantation genetic testing: a qualitative study7
ESHRE guideline: endometriosis7
The effect of pre-analytical variables on downstream application and data analysis of human endometrial biopsies7
The impact of HBV, HCV, or syphilis infections on embryo and pregnancy outcomes in couples undergoing IVF treatment: a matched cohort study7
Fertility preservation and fertility treatment in transgender adolescents and adults in a Swedish region, 2013–20187
A blended preconception lifestyle programme for couples undergoing IVF: lessons learned from a multicentre randomized controlled trial7
Variability and implications of recurrent implantation failure definitions used in the scientific literature: a systematic review7
Now is the time to introduce new innovative assisted reproduction methods to implement accessible, affordable, and demonstrably successful advanced infertility services in resource-poor countries7
Blood plasma trimethylamine N-oxide and related metabolites and asthenozoospermia odds: a hospital-based matched case–control study in China7
Preliminary report of intraovarian injections of autologous platelet-rich plasma (PRP) in extremely poor prognosis patients with only oocyte donation as alternative: a prospective cohort study7
Birth rate decline in the later phase of the COVID-19 pandemic: the role of policy interventions, vaccination programmes, and economic uncertainty7
Steady morphokinetic progression is an independent predictor of live birth: a descriptive reference for euploid embryos7
Asian women with PCOS have enhanced ovarian reserve and ART outcomes, even at an advanced maternal age: a model for reproductive longevity?6
Association between maternal MTHFR C677T/A1298C combination polymorphisms and IVF/ICSI outcomes: a retrospective cohort study6
Conventional outcome reporting per IVF cycle/embryo transfer may systematically underestimate chances of success for women undergoing ART: relevant biases in registries, epidemiological studies, and g6
The risk of miscarriage following surgical treatment of heterotopic extrauterine pregnancies6
Evidence and consensus on technical aspects of embryo transfer6
Reply to: ‘Hiding in plain sight’ and ‘Caution is needed when communicating analyses based on an apple to orange comparison’6
Clavien–Dindo, comprehensive complication index and classification of intraoperative adverse events: a uniform and holistic approach in adverse event registration for (deep) endometriosis surgery6
Androgen excess disorders remain undiagnosed in one of every four premenopausal women with Type 1 diabetes6
Preconception depression reduces fertility: a couple-based prospective preconception cohort6
No additional risk of congenital anomalies after first-trimester dydrogesterone use: a systematic review and meta-analysis5
Reproductive outcomes following recurrent first-trimester miscarriage: a retrospective cohort study5
Evidence-based guideline: premature ovarian insufficiency,5
Human Reproduction Open, a wild mustang in the prairie of science5
Lab-based semen parameters as predictors of long-term health in men—a systematic review5
Good practice recommendations for information provision for those involved in reproductive donation†5
The long and winding road leading to evidence-based medicine5
Visceral and subcutaneous adipose tissue in children born after ART with frozen and fresh embryo transfers5
Generating human primordial germ cell-like cells from pluripotent stem cells: a scoping review of in vitro methods5
Life’s Essential 8 score and its association with sperm quality parameters in reproductive-aged men: evidence from the Led-Fertyl cohort5
Adolescent attachment to parents and peers in singletons and twins born with assisted and natural conception5
Silk-Ovarioids: establishment and characterization of a human ovarian primary cell 3D-model system4
MICROBIOME DYSBIOSIS AND ENDOMETRIOSIS: A SYSTEMATIC SCOPING REVIEW OF CURRENT LITERATURE AND KNOWLEDGE GAPS4
Reply: Paternal age and neonatal health: unraveling epigenetic pathways4
Progressively diminished estrogen signaling concordant with increased fibrosis in ectopic endometrium4
Endometrial compaction shows no association with improved pregnancy outcomes in hormonal replacement frozen-thawed embryo transfer: an analysis of over 16 000 cases4
Measurement of changes in uterine and fibroid volume during treatment of heavy menstrual bleeding (HMB)4
Association of ambient air pollutant mixtures with IVF/ICSI-ET clinical pregnancy rates during critical exposure periods4
Extended versus conventional letrozole regimen in patients with polycystic ovary syndrome undergoing their first ovulation induction cycle: a prospective randomized controlled trial4
AI predictive models and advancements in microdissection testicular sperm extraction for non-obstructive azoospermia: a systematic scoping review4
Dynamic peripheral blood microRNA expression landscape during the peri-implantation stage in women with successful pregnancy achieved by single frozen-thawed blastocyst transfer4
FAP+ activated fibroblasts are detectable in the microenvironment of endometriosis and correlate with stroma composition and infiltrating CD8+ and CD68+ cells4
Modeling the window of implantation: Insights from endometrial biopsy and menstrual blood-derived organoids and endometrial stromal cells4
The mid-secretory endometrial transcriptomic landscape in endometriosis: a meta-analysis4
Building a family at advanced parental age: a systematic review on the risks and opportunities for parents and their offspring4
Maternal and obstetric outcomes are influenced by developmental stage and cryopreservation of transferred embryos after clomiphene citrate-based minimal stimulation IVF4
SARS-CoV-2 infection in IVF-conceived early pregnancy and the risk of miscarriage: a matched retrospective cohort study4
Why does the recurrent implantation failure literature need to be rewritten?4
Endometrial compaction to predict pregnancy outcomes in patients undergoing assisted reproductive technologies: a systematic review and meta-analysis3
Caution is needed when communicating analyses based on an apple to orange comparison3
Endometriosis classification systems: an international survey to map current knowledge and uptake3
Cancer risk in children, adolescents, and young adults conceived by ART in 1983–20113
HROpen—open, accessible and now with an impact factor!3
Prior exposure to alkylating agents negatively impacts testicular organoid formation in cells obtained from childhood cancer patients3
Facilitators and barriers for home-based monitoring to time frozen embryo transfers in IVF among women and healthcare providers3
Endometriosis and oocyte quality: an analysis of 13 614 donor oocyte recipient and autologous IVF cycles3
The functional ovarian anatomy of 492 women aged 18–22 years: a population-based study in Norway3
Pretreatment with oral contraceptive pills in women with PCOS scheduled for IVF: a randomized clinical trial3
A new human in vitro model of cytotypic and testosterone-producing organoids derived from testicular tissue of transgender women3
Reply: Absence of evidence is not evidence of absence for first trimester dydrogesterone-induced birth defects3
Anxiety in couples undergoing IVF: evidence from E-Freeze randomised controlled trial3
Infertility prevalence and the methods of estimation from 1990 to 2021: a systematic review and meta-analysis3
Predicting serum hormone concentration by estimation of urinary hormones through a home-use device3
Hypoxia exposure impairs male fertility via inhibiting Septin2-mediated spermatogonial proliferation3
Genetic determinants of testicular sperm extraction outcomes: insights from a large multicentre study of men with non-obstructive azoospermia3
COVID-19 pandemic and the consequential effect on patients with endometriosis3
Proteomic and metabolomic insights into oxidative stress response activation in mouse embryos generated by in vitro fertilization3
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