Human Reproduction Open

Papers
(The median citation count of Human Reproduction Open is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)
ArticleCitations
Testicular tissue transplantation: from animal models to clinical application212
Perfluorooctane sulfonate (PFOS) in follicular fluid and human granulosa cell dysfunction: a physiologically based toxicokinetic model translation of long-term low-level in vitr209
Comprehensive 16S rRNA gene sequencing and meta-transcriptomic analyses of the female reproductive tract microbiota: two molecular profiles with different messages172
Pregnancy and perinatal outcomes after modified natural cycle-frozen embryo transfers according to size of the dominant follicle on the hCG trigger day115
Correction to: Ovarian ferroptosis induced by androgen is involved in pathogenesis of PCOS105
Defending access to reproductive health information98
Extracellular vesicles secreted by human aneuploid embryos present a distinct transcriptomic profile and upregulate MUC1 transcription in decidualised endometrial stromal cells70
JUNO-coated beads as a functional assay to capture and characterize fertilization-competent human sperm53
Risk factors associated with monozygotic twinning in offspring conceived by assisted reproductive technology51
In infertile women with subclinical hypothyroidism, with or without thyroid peroxidase antibodies, serum TSH during pregnancy follows preconception values and thyroid hormones remain stable50
Biallelic mutations in RNA-binding protein ADAD2 cause spermiogenic failure and non-obstructive azoospermia in humans45
Spermatocyte injection into meiotic oocytes rescues diplotene, but not pachytene, arrest in azoospermic mutant mice39
Bridging the gap: meta-epidemiological analysis on the clinical translation of stem cell-based therapies in women’s reproductive diseases34
Birth outcomes in mothers with hypertensive disorders and polycystic ovary syndrome: a population-based cohort study26
A comprehensive study of common and rare genetic variants in spermatogenesis-related loci identifies new risk factors for idiopathic severe spermatogenic failure24
Ovarian ferroptosis induced by androgen is involved in pathogenesis of PCOS24
Current global status of male reproductive health24
Blastocyst telomere length predicts successful implantation after frozen-thawed embryo transfer23
Why the hypothesis of embryo selection in IVF/ICSI must finally be reconsidered22
Timing and tempo of pubertal development and substance use in adolescence: a cohort study in the Danish National Birth Cohort22
Effects of different embryo culture media on birthweight following assisted reproductive technology21
Independent factors associated with intracytoplasmic sperm injection outcomes in patients with complete azoospermia factor c microdeletions19
Multi-omics analysis of uterine fluid extracellular vesicles reveals a resemblance with endometrial tissue across the menstrual cycle: biological and translational insights19
Phytochemical consumption and the risk of teratozoospermia: findings from a hospital-based case–control study in China19
Reproductive factors and their association with physical and comprehensive frailty in middle-aged and older women: a large-scale population-based study18
Correction to: Fresh and cumulative live birth rates in mild versus conventional stimulation for IVF cycles in poor ovarian responders: a systematic review and meta-analysis17
Effects of maternal poor ovarian response on the reproductive endocrine profiles of the next generation: a prospective cohort study in China17
Double vitrification and warming does not compromise the chance of live birth—a potential invalid conclusion17
Automatic identification of human spermatozoa with zona pellucida-binding capability using deep learning17
Effect of pubertal induction with combined gonadotropin therapy on testes development and spermatogenesis in males with gonadotropin deficiency: a cohort study16
Effects of ovarian stimulation on embryo euploidy: an analysis of 12 874 oocytes and 3106 blastocysts in cycles with preimplantation genetic testing for monogenic disorders16
First trimester growth after fresh or frozen single embryo transfer: embryo cleavage vs blastocyst stages16
Bone mineralization in children aged 7–10 years born after ART with frozen and fresh embryo transfer16
Return rates for the use of ovarian tissue cryopreserved prior to gonadotoxic treatment as fertility preservation: a systematic review16
The thicker the endometrium, the better the neonatal outcomes?14
Biopsy vs comprehensive embryo/blastocyst analysis: a closer look at embryonic chromosome evaluation14
Human umbilical cord platelet-rich plasma to treat endometrial pathologies: methodology, composition and pre-clinical models13
Obstetric and perinatal outcomes in women with previous breast cancer: a nationwide study of singleton births 1973–201712
The impact of small and asymptomatic intramural and subserosal fibroids on female fertility: a case–control study12
Bisphenol-A disturbs hormonal levels and testis mitochondrial activity, reducing male fertility12
Development of deep pelvic endometriosis following acute haemoperitoneum: a prospective ultrasound study12
Low ovarian reserve and risk of miscarriage in pregnancies derived from assisted reproductive technology12
Hiding in plain sight12
Use of mesenchymal stem cells to enhance or restore fertility potential: a systematic review of available experimental strategies11
Reply: Artificial intelligence as a door opener for a new era of human reproduction11
Unveiling the paradox—low ovarian reserve in ART pregnancies and the hidden opportunities in research11
Reply: Emerging evidence of endometrial compaction in predicting ART outcomes10
Ovarian reserve in reproductive-aged patients with cancer before gonadotoxic treatment: a systematic review and meta-analysis10
The lack of evidence behind over-the-counter antioxidant supplements for male fertility patients: a scoping review10
Speaking up for the safety of the children following frozen embryo transfer10
Unmasking the risk: clinical trials versus real-world evidence on dydrogesterone and birth defects10
Technical specificities of the study of the mitochondrial genome9
Association of maternal pre-existing atherosclerotic cardiovascular disease and neonatal and long-term offspring outcomes: a nationwide mother–child paired cohort9
Impact of glucose metabolism abnormalities on live birth rate in South-East Asian women with polycystic ovary syndrome9
Birth defects reporting and the use of dydrogesterone: a disproportionality analysis from the World Health Organization pharmacovigilance database (VigiBase)9
Reply to: Anti-anonymity should not be taken more seriously than other positions on gamete donation9
Correction to: Birth defects reporting and the use of dydrogesterone: a disproportionality analysis from the World Health Organization pharmacovigilance database (VigiBase)9
The risk of asthma in singletons conceived by ART: a retrospective cohort study9
Bi-allelic variants in DNAH3 cause male infertility with asthenoteratozoospermia in humans and mice9
IVF in endometriosis: emerging evidence of exacerbation of pelvic pain and potential predictors9
Lateral distribution of endometriotic lesions: the anatomical recesses hypothesis. A systematic review and meta-analysis9
Women may not benefit from repeated frozen embryo transfers: a retrospective analysis of the cumulative live birth rate of 43 972 women8
Fertility preservation in women with endometriosis8
Organoids simulating the bovine oviduct mediate the embryo–maternal interface via extracellular vesicle-transmitted signaling8
Genetic architecture of congenital hypogonadotropic hypogonadism: insights from analysis of a Portuguese cohort8
Reassessing pre-existing comorbidity patterns in testicular cancer: controversies and future directions8
Paternal age and neonatal health: unraveling epigenetic pathways8
The impact of in utero exposure to cancer treatments on foetal reproductive development and future fertility: a systematic review8
Fertility preservation in adult male patients with cancer: a systematic review and meta-analysis8
Improving sperm selection strategies for assisted reproduction through closing the knowledge gap in sperm maturation mechanics8
The impact of HBV, HCV, or syphilis infections on embryo and pregnancy outcomes in couples undergoing IVF treatment: a matched cohort study7
Study protocol for a Developmental Epidemiological Study of Children born through Reproductive Technologies (DESCRT)7
Mental health of couples affects fertility, modified by socioeconomic status: a couple-based analysis7
A blended preconception lifestyle programme for couples undergoing IVF: lessons learned from a multicentre randomized controlled trial7
Reply: Fetal safety of dydrogesterone: clarifying the role of pharmacovigilance7
Steady morphokinetic progression is an independent predictor of live birth: a descriptive reference for euploid embryos7
Variability and implications of recurrent implantation failure definitions used in the scientific literature: a systematic review7
No evidence of a causal relationship between miscarriage and 25-hydroxyvitamin D: a Mendelian randomization study7
Blood plasma trimethylamine N-oxide and related metabolites and asthenozoospermia odds: a hospital-based matched case–control study in China7
ESHRE PGT Consortium data collection XXI: PGT analyses in 20187
Non-significant results do not imply similarity or safety in NC-FET follicle-size comparisons: a clarification7
Now is the time to introduce new innovative assisted reproduction methods to implement accessible, affordable, and demonstrably successful advanced infertility services in resource-poor countries7
Asian women with PCOS have enhanced ovarian reserve and ART outcomes, even at an advanced maternal age: a model for reproductive longevity?7
Frozen versus fresh embryo transfer on perinatal outcomes—do endometrial preparation methods matter?6
Generating human primordial germ cell-like cells from pluripotent stem cells: a scoping review of in vitro methods6
Birth rate decline in the later phase of the COVID-19 pandemic: the role of policy interventions, vaccination programmes, and economic uncertainty6
Conventional outcome reporting per IVF cycle/embryo transfer may systematically underestimate chances of success for women undergoing ART: relevant biases in registries, epidemiological studies, and g6
Androgen excess disorders remain undiagnosed in one of every four premenopausal women with Type 1 diabetes6
Reply to: ‘Hiding in plain sight’ and ‘Caution is needed when communicating analyses based on an apple to orange comparison’6
Lab-based semen parameters as predictors of long-term health in men—a systematic review6
Preconception depression reduces fertility: a couple-based prospective preconception cohort6
Clavien–Dindo, comprehensive complication index and classification of intraoperative adverse events: a uniform and holistic approach in adverse event registration for (deep) endometriosis surgery6
Association between maternal MTHFR C677T/A1298C combination polymorphisms and IVF/ICSI outcomes: a retrospective cohort study5
Modeling the window of implantation: insights from endometrial biopsy and menstrual blood-derived organoids and endometrial stromal cells5
Menstrual fluid-derived small extracellular vesicles: a novel reservoir with distinct molecular signatures and implications for endometriosis etiopathology5
Life’s Essential 8 score and its association with sperm quality parameters in reproductive-aged men: evidence from the Led-Fertyl cohort5
Evidence-based guideline: premature ovarian insufficiency,5
Correction to: Pregnancy and perinatal outcomes after modified natural cycle-frozen embryo transfers according to size of the dominant follicle on the hCG trigger day5
Do different male infertility factors impact embryological, cumulative pregnancy and neonatal outcomes in IVF/ICSI cycles? A retrospective cohort study5
Human Reproduction Open, a wild mustang in the prairie of science5
Visceral and subcutaneous adipose tissue in children born after ART with frozen and fresh embryo transfers5
No additional risk of congenital anomalies after first-trimester dydrogesterone use: a systematic review and meta-analysis5
Microbiome dysbiosis and endometriosis: a systematic scoping review of current literature and knowledge gaps4
Silk-Ovarioids: establishment and characterization of a human ovarian primary cell 3D-model system4
AI predictive models and advancements in microdissection testicular sperm extraction for non-obstructive azoospermia: a systematic scoping review4
Atopic dermatitis and fecundity: a Danish National Birth Cohort study4
SARS-CoV-2 infection in IVF-conceived early pregnancy and the risk of miscarriage: a matched retrospective cohort study4
When drugs meet disease: disentangling diabetes, obesity, and periconceptional GLP-1 receptor agonist safety4
Vaginal microbial community state types fail to predict IVF outcomes, whereas Ureaplasma parvum and Lactobacillus iners 4
Association of ambient air pollutant mixtures with IVF/ICSI-ET clinical pregnancy rates during critical exposure periods4
Reply: Paternal age and neonatal health: unraveling epigenetic pathways4
Comparative effect of different surgical treatments for ovarian endometrioma on anti-Müllerian hormone levels: a systematic review and network meta-analysis4
Endometrial compaction shows no association with improved pregnancy outcomes in hormonal replacement frozen-thawed embryo transfer: an analysis of over 16 000 cases4
Effect of progesterone timing on live birth rates in day-6 blastocyst frozen-thawed embryo transfer cycles: a randomized controlled trial4
Extended versus conventional letrozole regimen in patients with polycystic ovary syndrome undergoing their first ovulation induction cycle: a prospective randomized controlled trial4
Building a family at advanced parental age: a systematic review on the risks and opportunities for parents and their offspring4
Measurement of changes in uterine and fibroid volume during treatment of heavy menstrual bleeding (HMB)4
Dynamic peripheral blood microRNA expression landscape during the peri-implantation stage in women with successful pregnancy achieved by single frozen-thawed blastocyst transfer4
Progressively diminished estrogen signaling concordant with increased fibrosis in ectopic endometrium4
Why does the recurrent implantation failure literature need to be rewritten?4
Genetic determinants of testicular sperm extraction outcomes: insights from a large multicentre study of men with non-obstructive azoospermia4
The functional ovarian anatomy of 492 women aged 18–22 years: a population-based study in Norway3
Is polycystic ovary syndrome associated with uterine malformations? A systematic review using Bradford Hill’s causality framework3
Prior exposure to alkylating agents negatively impacts testicular organoid formation in cells obtained from childhood cancer patients3
Reply: Absence of evidence is not evidence of absence for first trimester dydrogesterone-induced birth defects3
Anxiety in couples undergoing IVF: evidence from E-Freeze randomised controlled trial3
Thyroid cancer treatment among adolescents and young adult women and reproductive outcomes: a population-based cohort study3
Hypoxia exposure impairs male fertility via inhibiting Septin2-mediated spermatogonial proliferation3
Cancer risk in children, adolescents, and young adults conceived by ART in 1983–20113
FAP+ activated fibroblasts are detectable in the microenvironment of endometriosis and correlate with stroma composition and infiltrating CD8+ and CD68+ cells3
A new human in vitro model of cytotypic and testosterone-producing organoids derived from testicular tissue of transgender women3
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