npj Digital Medicine

Article	Citations
Prognostic model and U-shaped SBP-risk correlation in unstable pelvic fractures with TBI	898
A comparison of self-reported COVID-19 symptoms between android and iOS CoronaCheck app users	807
Interpretable Multiomics Models for Predicting Surgical Interventions and Blood Transfusion Requirements in Traumatic Brain Injury	649
Computational strategic recruitment for representation and coverage studied in the All of Us Research Program	624
Will AI become our Co-PI?	570
Addressing racial disparities in surgical care with machine learning	544
Validation of Amazon Halo Movement: a smartphone camera-based assessment of movement health	506
Metabolomic characterization of frailty identifies subtype-specific management strategies	469
Defining digital surgery for the future	426
Rapid prediction of cardiac activation in the left ventricle with geometric deep learning: a step towards cardiac resynchronization therapy planning	368
Unobtrusive inference of diurnal rhythms from smartphone data	363
Clinical outcomes and reporting quality of large language model interventions in practice: a systematic evidence map	362
Human expertise or artificial intelligence? A prospective study on nail disorder diagnosis	349
Data and knowledge-driven imaging biomarkers for lumbar aging and degenerative risk stratification monitoring	344
Forecasting Alzheimer’s disease progression via identity-preserved denoising diffusion generative adversarial network	341
Use of AI scribes in UK primary care: a survey of general practitioners	338
Breaking geographic and language barriers in neuropsychology: online administration of MoCA in diverse populations	336
Human–AI collaboration for dysphagia rehabilitation from effectiveness to implementation complexity: a systematic review	327
Incorporating large language models as clinical decision support in oncology: the Woollie model	324
Patch-to-slide fusion deep learning model for histological diagnosis of early pregnancy loss including hydatidiform mole	315
Why we should not mistake accuracy of medical AI for efficiency	303
Foundation model embeddings for multimodal oncology data integration	302
Machine learning model for differentiating xanthogranulomatous cholecystitis and gallbladder cancer in multicenter largescale study	292
A hybrid machine learning approach for the personalized prognostication of aggressive skin cancers	281
Challenges in applying the EU AI act research exemptions to contemporary AI research	270

Negative control-calibrated difference-in-difference analyses: addressing unmeasured confounding in RWD with application to racial/ethnic differences	266
Seasonal timing and interindividual differences in shiftwork adaptation	264
DARE-FUSE: domain aligned evidence guided learning for joint brain tumor MRI segmentation and classification	251
India’s evolving digital health strategy	250
Predicting 1-year successful clinical use of an arteriovenous access for hemodialysis using machine learning	235
Differentiable centerline-aware framework for aneurysm neck delineation in volumetric angiography	214
Prevalence and course of pregnancy symptoms using self-reported pregnancy app symptom tracker data	212
Dose–response relationship between computerized cognitive training and cognitive improvement	201
Promoting racial equity in digital health: applying a cross-disciplinary equity framework	193
Clinical usefulness of digital twin guided virtual amiodarone test in patients with atrial fibrillation ablation	191
Early adverse physiological event detection using commercial wearables: challenges and opportunities	189
Whole slide image based deep learning refines prognosis and therapeutic response evaluation in lung adenocarcinoma	177
The impact of inconsistent human annotations on AI driven clinical decision making	175
QoQ-Med3: a multimodal reasoning foundation model for clinical analysis	170
Clinically meaningful interpretability of an AI model for ECG classification	166
A randomized trial of a mobile health intervention to augment cardiac rehabilitation	163
Scoping review of deep learning research illuminates artificial intelligence chasm in otolaryngology-head and neck surgery	155
A clinician aligned vision language framework for stepwise interpretation in fundus fluorescein angiography	148
Machine learning-based forecasting of daily acute ischemic stroke admissions using weather data	147
Reasoning red teaming in healthcare not all paths to a desired outcome are desirable	146
Challenges and recommendations for enhancing digital data protection in Indian Medical Research and Healthcare Sector	145
AI-based skin cancer detection: the balance between access and overutilization	137
Brain contrastive modeling reveals depression subtypes with distinct treatment response and progression	136
TIMER: temporal instruction modeling and evaluation for longitudinal clinical records	134
Multimodal analysis of whole slide images in colorectal cancer	134
Generalized multi task learning framework for glucose forecasting and hypoglycemia detection using simulation to reality	126
Simulation of covariate and concept drift in machine learning hospital admission prediction from emergency triage	125
Effectiveness of gamified team competition as mHealth intervention for medical interns: a cluster micro-randomized trial	125
Protecting clinical value judgment in the age of AI	124
Small language models learn enhanced reasoning skills from medical textbooks	124
Patient agency and large language models in worldwide encoding of equity	122
An adversarial training framework for mitigating algorithmic biases in clinical machine learning	120
Evaluating evidence-based health information from generative AI using a cross-sectional study with laypeople seeking screening information	120
A Representation Fusion Framework for Decoupling Diagnostic Information in Multimodal Learning	119
Machine learning on interictal intracranial EEG predicts surgical outcome in drug resistant epilepsy	119
Evaluating human-in-the-loop strategies for artificial intelligence-enabled translation of patient discharge instructions: a multidisciplinary analysis	116
Author Correction: Self-supervised learning of accelerometer data provides new insights for sleep and its association with mortality	115
Large language models-enabled digital twins for precision medicine in rare gynecological tumors	113
AI-driven virtual cell models in preclinical research: technical pathways, validation mechanisms, and clinical translation potential	112
Computational network models for forecasting and control of mental health trajectories in digital applications	112
Policy brief: ambient AI scribes and the coding arms race	112
Establishing organizational AI governance in healthcare: a case study in Canada	112
Next-generation AI framework for comprehensive oral leukoplakia evaluation and management	108
A scoping review of reporting gaps in FDA-approved AI medical devices	107
Systematic review to understand users perspectives on AI-enabled decision aids to inform shared decision making	107
Situating governance and regulatory concerns for generative artificial intelligence and large language models in medical education	106
Prompt-mamba filtering networks for accurate hepatocellular carcinoma lesion segmentation in abdominal CT	105
Real world evidence for altered communication patterns in individuals with autism spectrum disorder	104
Variational Bayes machine learning for risk adjustment of general outcome indicators with examples in urology	104
Exploiting large language models for diagnosing autism associated language disorders and identifying distinct features	103

Intelligent quality control for first trimester ultrasound scans in Liaoning Province of China	102
High-dimensional item response theory analysis of patient-reported outcomes in total knee arthroplasty	102
Credibility assessment of a mechanistic model of atherosclerosis to predict cardiovascular outcomes under lipid-lowering therapy	101
Association of accelerometer-derived circadian abnormalities and genetic risk with incidence of atrial fibrillation	101
Identifying what works in mental health apps through meta-regression analyses of 169 trials	99
Matters arising: Utilizing foundation models for developing clinical tools	99
In-ear infrasonic hemodynography with a digital health device for cardiovascular monitoring using the human audiome	99
PAM: a propagation-based model for segmenting any 3D objects across multi-modal medical images	98
ScarElastic: continuous elasticity field modeling for myocardial scar delineation in LGE-CMR	98
Boosting foundation models for rare eye disease diagnosis via a multimodal text-to-image generative framework	98
Impact of the new European medical device regulation on digital health manufacturers	98
Deep learning for malignancy and tumor origin prediction using cytology or histopathology whole slide images	98
Publisher Correction: Development and assessment of a machine learning tool for predicting emergency admission in Scotland	96
A dynamic risk prediction framework for Alzheimer's disease and related dementias with interpretability	95
Development and application of an intelligent assessment system for medical clinical skill training	95
Real-time AI-assisted quality control during nasopharyngolaryngoscopy: a randomized controlled trial	94
A Bayesian-driven approach to identify racial inequities in longitudinal care delivery	93
Age, emotional burden and deep brain stimulation electrode location shape Parkinson’s disease quality of life	93
AI-driven smartphone screening for acute COPD exacerbations: enhancing health equity in developing regions	93
A scoping review of ethical aspects of public-private partnerships in digital health	93
Antecedents and consequences of different indicators of engagement with a digital intervention for tobacco cessation	93
Interpretable graph deep learning framework for drug synergy prediction by integrating functional and clinical similarities	91
A typology of physician input approaches to using AI chatbots for clinical decision-making	91
Reimagining psychiatric care with agentic AI: promise, challenges, and a roadmap forward	90
Integrating personalized shape prediction, biomechanical modeling, and wearables for bone stress prediction in runners	90
Improving medical machine learning models with generative balancing for equity and excellence	89
Trial emulation for validating the clinical efficacy of a foundational AI model in embryo selection	89
Fibricheck detection capabilities for atrial fibrillation (FDA–AF): a multicenter validation study	89
The impact of expanded telehealth availability on primary care utilization	86
Real-world multicenter assessment of sustained clinical outcomes after digital deep brain stimulation	85
Development and validation of a novel blood-based biomarker for gastric cancer triage in chronic dyspepsia	85
Joint AI-driven event prediction and longitudinal modeling in newly diagnosed and relapsed multiple myeloma	85
Cohort vs case–control design for transformer-based prediction of asthma exacerbations in mild asthma	84
Leveraging generative AI to prioritize drug repurposing candidates for Alzheimer’s disease with real-world clinical validation	84
Demographic bias in public remote photoplethysmography datasets	83
The relation between passively collected data and PTSD: a systematic review and meta-analysis	83
The performance of a deep learning system in assisting junior ophthalmologists in diagnosing 13 major fundus diseases: a prospective multi-center clinical trial	82
Meta-analysis of randomized controlled trials of electronic health interventions to reduce medication errors	82
Impact of missing electronic fetal monitoring signals on perinatal asphyxia: a multicohort analysis	81
Making machine learning matter to clinicians: model actionability in medical decision-making	80
Effectiveness of telehealth versus in-person care during the COVID-19 pandemic: a systematic review	80
Anatomically-guided Masked Autoencoder with Domain-Adaptive Prompting (AMAP) for multimodal cerebral aneurysm detection and segmentation	80
Non-invasive chronic kidney disease risk stratification tool derived from retina-based deep learning and clinical factors	80
Disparities in cannabis use and documentation in electronic health records among children and young adults	80
Large language model agents can use tools to perform clinical calculations	79
An active inference strategy for prompting reliable responses from large language models in medical practice	79
Transdiagnostic-focused apps for depression and anxiety: a meta-analysis	78
Predicting outcomes following endovascular aortoiliac revascularization using machine learning	77
A Novel method for quantifying fluctuations in wearable derived daily cardiovascular parameters across the menstrual cycle	77
Integrating digital gait data with metabolomics and clinical data to predict outcomes in Parkinson’s disease	77
A Global meta-analysis of digital divide in psychiatric population from 2004 to 2023	76
An Interpretable AI System for Oral Leukoplakia Progression: From Early Screening to Lesion Delineation	76
Telehealth virtual reality intervention reduces chronic pain in a randomized crossover study	75
A distributional reinforcement learning model for temporal coagulation balance evaluation and state‑guided supportive suggestions	75
A weakly supervised transformer for rare disease diagnosis and subphenotyping from EHRs with pulmonary case studies	75
Classification of intracranial pressure epochs using a novel machine learning framework	74
Skin Tone Analysis for Representation in Educational Materials (STAR-ED) using machine learning	74
KT-LLM: an evidence-grounded and sequence text framework for auditable kidney transplant modeling	74
Combined telemonitoring and telecoaching for heart failure improves outcome	73
Exploring the potential of digital biomarkers as a measure of brain health ‘capital’	73
Association of primary care telehealth with preventable healthcare utilization and care continuity among patients with chronic conditions	73
The regulation of artificial intelligence in intensive care units: from narrow tools to generalist systems	73
Using digital technologies to diagnose in the home: recommendations from a Delphi panel	72
Circadian rhythm biomarker from wearable device data is related to concurrent antidepressant treatment response	72
Do engagement and behavioural mechanisms underpin the effectiveness of the Drink Less app?	72
Implementation report on pioneering federated data access for the German National Emergency Department Data Registry	71
Applying machine learning to consumer wearable data for the early detection of complications after pediatric appendectomy	71
From virtual patients to digital twins in immuno-oncology: lessons learned from mechanistic quantitative systems pharmacology modeling	71
When helpfulness backfires: LLMs and the risk of false medical information due to sycophantic behavior	71
A multimodal uncertainty-aware AI system optimizes ovarian cancer risk assessment workflow	70
Artificial intelligence-based personalized treatment strategies for unresectable hepatocellular carcinoma: integrating HSP90α for prognosis and survival prediction	70
Predicting appropriateness of antibiotic treatment among ICU patients with hospital-acquired infection	70
Clinician engagement shapes the impact of AI-based ECG screening for chronic liver disease in primary care	69
AI in Histopathology Explorer for comprehensive analysis of the evolving AI landscape in histopathology	69
Physics-informed neural networks for modeling physiological time series for cuffless blood pressure estimation	68
Digital versus in-person physical therapy for osteoarthritis pain and function	67
Integrating multi-omics and machine learning systematically deciphers cellular heterogeneity and fibrotic regulatory networks in the progression from MASLD to MASH	67
Deep learning-based mobile application for efficient eyelid tumor recognition in clinical images	67
Predicting recovery after stressors using step count data derived from activity monitors	66
AFP assistant: a retrieval-augmented generation and large language model-powered multilingual polio chatbot for low-resource language communities	65

African digital health strategic plans analysis: key weaknesses in contextualization, intervention focus, and technological foresight	65
Benchmarking large language models for personalized, biomarker-based health intervention recommendations	64
Implementing quality management systems to close the AI translation gap and facilitate safe, ethical, and effective health AI solutions	64
Enhancing ocular sign detection: AI-based strategic segmentation for improved accuracy and privacy protection	63
Accuracy of dental implant placement using different dynamic navigation and robotic systems: an in vitro study	63
Real-time near infrared artificial intelligence using scalable non-expert crowdsourcing in colorectal surgery	63
Improving prognostic accuracy in lung transplantation using unique features of isolated human lung radiographs	62
Author Correction: Leveraging AI and transfer learning to enhance out-of-hospital cardiac arrest outcome prediction in diverse setting	62
A randomized controlled trial of a digital lifestyle intervention involving postoperative patients with colorectal cancer	62
Effective monitoring of online AI decision-making algorithms in just-in-time adaptive interventions	62
Multimodal machine learning for risk-stratified bundled payments in spinal surgery	62
Multicenter evaluation of interpretable AI for coronary artery disease diagnosis from PET biomarkers	62
Deep learning based volumetric analysis of infrarenal abdominal aortic aneurysms characterized on CTA	62
A unified deep learning framework for cross-platform harmonization of multi-tracer PET quantification in neurodegenerative disease	61
Deep learning-enabled multiphoton microscopy predicts colorectal cancer recurrence from routine FFPE specimens	61
Evaluating commercial multimodal AI for diabetic eye screening and implications for an alternative regulatory pathway	61
A multilevel meta-analysis of passive smartphone sensing of adolescent mental health	61
Self-supervised identification and elimination of harmful datasets in distributed machine learning for medical image analysis	61
Sensor wide association studies in digital medicine	61
Author Correction: Enhancing attention in children using an integrated cognitive-physical videogame: A pilot study	61
Diagnostic accuracy of telemedicine for detection of surgical site infection: a systematic review and meta-analysis	60
Publisher Correction: Rapid prediction of cardiac activation in the left ventricle with geometric deep learning: a step towards cardiac resynchronization therapy planning	60
AI technology to support adaptive functioning in neurodevelopmental conditions in everyday environments: a systematic review	59
Artificial intelligence tools in supporting healthcare professionals for tailored patient care	59
Optical coherence tomography choroidal enhancement using generative deep learning	59
Development of a multimodal large language model for early warning and diagnosis of chronic ocular GVHD	58
Large language models for acute coronary syndrome triage at first medical contact in emergency departments	58
Comparative analysis of natural language processing methodologies for classifying computed tomography enterography reports in Crohn’s disease patients	58
Diagnosing pathologic myopia by identifying morphologic patterns using ultra widefield images with deep learning	58
Development and validation of an interpretable risk prediction model for the early classification of thalassemia	57
Dynamic associations between glucose and ecological momentary cognition in Type 1 Diabetes	57
Synthesized clinical notes enable training robust multimodal AI models from unimodal dermatology datasets	57
Examining human-AI interaction in real-world healthcare beyond the laboratory	57
A mobile health application that supports a patient centered approach to cardiovascular risk management	57
Blood glucose variance measured by continuous glucose monitors across the menstrual cycle	57
A simulation based digital twin approach to assessing the organization of response to emergency calls	57
The three-year evolution of Germany’s Digital Therapeutics reimbursement program and its path forward	56
Generative AI mental health chatbots: a scoping review of intervention design and user experience	56
Interpretable multimodal transformer for prediction of molecular subtypes and grades in adult-type diffuse gliomas	56
Responsible development of clinical speech AI: Bridging the gap between clinical research and technology	56
Engaging a national-scale cohort of smart thermometer users in participatory surveillance	56
Evaluation of causal reasoning for large language models in contextualized clinical scenarios of laboratory test interpretation	55
The case for inclusive co-creation in digital health innovation	55
Feasibility of anomaly score detected with deep learning in irradiated breast cancer patients with reconstruction	55
Text-image alignment for ILD imaging: linking CXR evidence to CT quantification	55
SpeechCARE: dynamic multimodal modeling for cognitive screening in diverse linguistic and speech task contexts	55
The hospital at home in the USA: current status and future prospects	54
Systematic review and meta-analysis of artificial intelligence in classifying HER2 status in breast cancer immunohistochemistry	54
Economic evaluation for medical artificial intelligence: accuracy vs. cost-effectiveness in a diabetic retinopathy screening case	54
Artificial intelligence-derived retinal age gap as a marker for reproductive aging in women	54
Prospective clinical evaluation of deep learning for ultrasonographic screening of abdominal aortic aneurysms	54
Peer perceptions of clinicians using generative AI in medical decision-making	53
Health data justice: building new norms for health data governance	53
Shortcut learning in medical AI hinders generalization: method for estimating AI model generalization without external data	53
Therapeutic outcomes of different treatment approaches for T1a-M3/T1b esophageal cancer and development of a prognostic prediction model	52
A framework for digital health equity	52
Shedding light on the dynamic interplay of positive and negative symptoms of psychosis with Behavioral Tractography	52
Closing the gap: addressing telehealth disparities across specialties in the sustained pandemic era	52
Vision-Enabled AI scribes reduce omissions in clinical conversations: evidence from simulated medication histories	51
Towards precision medicine based on a continuous deep learning optimization and ensemble approach	51
Continuous and componentized facial palsy measurement alignment and clinical interpretable model	51
Cross sectional pilot study on clinical review generation using large language models	51
Structure-aware multi-task learning with domain generalization for robust vertebrae analysis in spinal CT	51
A clinically actionable framework for personalizing iCBT to improve depression outcomes	51
Impact of an AI prognostic tool on clinician performance in colorectal liver metastases	51
A generative approach for semantic auditing of electronic health records	50
Leveraging large language models to extract smoking history from clinical notes for lung cancer surveillance	50
SynthEHR-eviction: enhancing eviction SDoH detection with LLM-augmented synthetic EHR data	50
Algorithm-driven HPV vaccine allocation paradigm for cervical cancer elimination targeting the Chinese population	50
AI-driven label-free Raman spectromics for intraoperative spinal tumor assessment	49
Streamlined machine learning model for early sepsis risk prediction in burn patients	49
Virtual fitness buddy ecosystem: a mixed reality precision health physical activity intervention for children	49
Knockoff-ML: a knockoff machine learning framework for controlled variable selection and risk stratification in electronic health record data	49
Expanding care coordination in an integrated health system through causal machine learning	49
Large language models require a new form of oversight: capability-based monitoring	48
Prediction of atrial fibrillation from at-home single-lead ECG signals without arrhythmias	48
Reimbursement in the age of generalist radiology artificial intelligence	47
Digital humanistic program to manage premature frailty in young breast cancer survivors with gender perspective	47
Biosignal-based screening of depressive symptoms during affective conversations with virtual humans	47
Guidance for unbiased predictive information for healthcare decision-making and equity (GUIDE): considerations when race may be a prognostic factor	47
Author Correction: Large-scale self-supervised video foundation model for intelligent surgery	47
Identifying unique gait phenotypes across neuromotor conditions using wearable inertial sensors and topological data analysis	47
A scoping review of explainable artificial intelligence for medical multimodal data	47
Machine learning based CAGIB score predicts in-hospital mortality of cirrhotic patients with acute gastrointestinal bleeding	47
Large language model-augmented offline reinforcement learning framework for sepsis management in critical care	47
Federated target trial emulation using distributed observational data for treatment effect estimation	47
Regular snoring is associated with uncontrolled hypertension	47
A real-world clinical validation for AI-based MRI monitoring in multiple sclerosis	46
Prediction of antibiotic-associated cutaneous adverse drug reactions using electronic health record foundation models	46
Noninvasive molecular subtyping of breast cancer using multimodal ultrasound spatiotemporal transformer	46
Injury prediction in elite women’s football: an integrative machine learning-based decision-support framework	46
Reinforcement learning improves LLM accuracy and reasoning in disease classification from radiology reports	46
Independent and collaborative performance of large language models and healthcare professionals in diagnosis and triage	46
A strategy for cost-effective large language model use at health system-scale	45
Predicting non-muscle invasive bladder cancer outcomes using artificial intelligence: a systematic review using APPRAISE-AI	45