npj Precision Oncology

Article	Citations
KMT2C inactivation leads to PTEN downregulation and tolerance to DNA damage during cell cycle progression	530
Circulating tumor DNA in ALK-positive anaplastic large cell lymphoma: a proof-of-concept study	279
Exosome- transported FER inhibitor suppresses progression of diffuse large B-cell lymphoma via regulating AJUBA/Hippo axis	214
BRAF v600E–mutant cancers treated with vemurafenib alone or in combination with everolimus, sorafenib, or crizotinib or with paclitaxel and carboplatin (VEM-PLUS) study	187
AI-enabled single-cell dissection of the palmitoylation landscape identifies a multicellular prognostic program in gastric cancer	175
Author Correction: An automated deep learning pipeline for EMVI classification and response prediction of rectal cancer using baseline MRI: a multi-centre study	163
Therapeutic responses in patients with advanced NSCLC enrolled in early-phase clinical trials at MD Anderson	159
Single nuclei and spatial profiling of sacrococcygeal teratomas reveals cellular composition and X inactivation heterogeneity	145
Benchmarking progression-free survival ratio as primary endpoint in precision oncology clinical trials	142
Deciphering brain metastasis in epithelial ovarian cancer: multimodal analysis and potential biomarkers	116
Evolving landscape of targeted immunotherapeutic interventions and CAR-T therapy for acute myeloid leukemia	116
Imaging and AI based chromatin biomarkers for diagnosis and therapy evaluation from liquid biopsies	110
Development and testing of a polygenic risk score for breast cancer aggressiveness	101
Multi-modal characterization of metabolic and immune gene clusters in adrenocortical carcinoma treatment	92
Robust multicentre detection and classification of colorectal liver metastases on CT: application of foundation models	87
Improved prediction of MAPKi response duration in melanoma patients using genomic data and machine learning	85
Endoplasmic reticulum stress in brain metastatic cascade	81
High-throughput screening identifies NT-1 that synergizes with MRTX1133 against acquired resistant KRASG12D colorectal cancer	81
Interferon signaling and ferroptosis in tumor immunology and therapy	80
MYSM1 promotes lung adenocarcinoma progression via TRAF2/3-mediated activation of MAPK and non-canonical NF-κB pathways	79
Comprehensive multi-omics analysis identifies cancer subtypes and prognostic signatures of hepatitis B virus-associated hepatocellular carcinoma	78
Inferring translational efficiency from transcriptomes improves noncanonical neoantigen prioritization and cancer patient stratification	75
Sub-regional radiomics combining multichannel 2-dimensional or 3-dimensional deep learning for predicting neoadjuvant chemo-immunotherapy response in esophageal squamous cell carcinoma: a multicenter	73
A protein-encoding CCDC7 circular RNA inhibits the progression of prostate cancer by up-regulating FLRT3	73
An automated deep learning pipeline for EMVI classification and response prediction of rectal cancer using baseline MRI: a multi-centre study	73

Grading of lung adenocarcinomas with simultaneous segmentation by artificial intelligence (GLASS-AI)	72
Development of a translational murine model for antibody-drug conjugate-induced interstitial lung disease	70
Co-targeting KRAS G12C and EGFR reduces both mutant and wild-type RAS-GTP	69
The dynamic immune behavior of primary and metastatic ovarian carcinoma	68
Constitutional mismatch repair deficiency mimicking Lynch syndrome is associated with hypomorphic mismatch repair gene variants	67
Tumor break load quantitates structural variant-associated genomic instability with biological and clinical relevance across cancers	67
Developing survival prediction models in colorectal cancer using epigenome-wide DNA methylation data from whole blood	65
Spatial transcriptomics reveals molecular heterogeneity and subtype-specific therapeutic targets in small cell lung cancer	64
Artificial intelligence-driven prediction of lymph node metastasis in T1 esophageal squamous cell carcinoma using whole slide images	64
Genome-wide analyses reveals an association between invasive urothelial carcinoma in the Shetland sheepdog and NIPAL1	61
Mucin-1: a promising pan-cancer therapeutic target	59
Complement activation in tumor microenvironment after neoadjuvant therapy and its impact on pancreatic cancer outcomes	59
A perspective on life-cycle health technology assessment and real-world evidence for precision oncology in Canada	59
Assessment of TROP2, CEACAM5 and DLL3 in metastatic prostate cancer: Expression landscape and molecular correlates	56
Barriers and opportunities in pancreatic cancer immunotherapy	54
A multi-center study on the consistency of drug sensitivity testing in patients with acute myeloid leukemia	52
Analyses of canine cancer mutations and treatment outcomes using real-world clinico-genomics data of 2119 dogs	51
Prospective implementation of an aqueous humor liquid biopsy platform informs clinical diagnosis and management of retinoblastoma and other intraocular lesions	51
User-centered design approach to visualize PROMs for molecular tumor boards	50
Pan-cancer molecular tumor board experience with biomarker-driven precision immunotherapy	50
AI-driven body composition atlas reveals its association with NSCLC immunotherapy outcome and molecular background: a multicenter study	48
Prolonged response to dual immune checkpoint blockade in patients with advanced solid tumors: a case series	48
Single-cell analysis identifies dysregulated cell type-specific gene programs and intercellular crosstalk underlying colorectal cancer	48
Multiregional transcriptomic profiling provides improved prognostic insight in localized non-small cell lung cancer	47
Histological transformation to gliosarcoma with combined BRAF/MEK inhibition in BRAF V600E mutated glioblastoma	47
Collagen disorder architecture features are associated with clinical, molecular, genetic factors and survival outcomes in colon cancer	47
Personalized signaling pathway analysis of gastrointestinal tumors for patient stratification and drug target evaluation using clinically derived core biopsies	47
AI-assisted histomorphological stratification of endometrial cancer: real-world validation of foundation models for molecular subtyping	46
Establishing predictive machine learning models for drug responses in patient derived cell culture	46
PD-1 blockade potentiates neoadjuvant chemotherapy in NSCLC via increasing CD127+ and KLRG1+ CD8 T cells	45
TRIM65 regulates glucose metabolic reprogramming to promote glioma cell proliferation via ubiquitination and degradation of AMPK	45
A universal immunohistochemistry analyzer for generalizing AI-driven assessment of immunohistochemistry across immunostains and cancer types	44
Targeting Nrf2/PHKG2 axis to enhance radiosensitivity in NSCLC	44
Erigoster B targeting DECR1 induces ferroptosis of breast cancer cells via promoting phosphatidylcholine/arachidonic acid metabolism	43
Enhanced efficacy of ipilimumab plus nivolumab in angiogenic subtypes of metastatic clear-cell renal cell carcinoma	43
ECM-based molecular subtypes define prognostic, EMT status, and therapeutic diversity in IDH-mutant gliomas	43
Venetoclax resistance in preclinical KMT2A-rearranged acute lymphoblastic leukemia models is characterized by high inter- and intra-model heterogeneity	42
Translational feasibility of a plasmonic microarray–based liquid biopsy for KRAS codon mutation detection across tissue, plasma, and urine in early colorectal cancer	42
Self-supervised attention-based deep learning for pan-cancer mutation prediction from histopathology	42
Comparative cost analysis of a diagnostic multi-omics platform for decision support in advanced cancer – results from the Tumor Profiler Melanoma project	42
Stage-dependent spatial distribution and prognostic value of CD8+ tissue-resident memory T cells in NSCLC	42
Stepwise malignant transformation from MHL to UESL via activation of C19MC and loss of TP53	42
Discovery of prognostic lncRNAs in colorectal cancer using spatial transcriptomics	41
Spatiotemporal multi-omics reveals lineage, spatial and functional heterogeneity of tumor-associated macrophages and therapeutic vulnerabilities in the tumor microenvironment	40
m6A reader IGF2BP2-stabilized lncRNA LHX1-DT inhibits renal cell carcinoma (RCC) cell proliferation and invasion by sponging miR-590-5p	39
Machine learning model for predicting tertiary lymphoid structures and treatment response in triple-negative breast cancer	38
Baseline biomarkers of efficacy and on-treatment immune-profile changes associated with bempegaldesleukin plus nivolumab	38
Relationship among DDR gene mutations, TMB and PD-L1 in solid tumour genomes identified using clinically actionable biomarker assays	38
Single-cell landscape of bronchoalveolar immune cells in patients with immune checkpoint inhibitor-related pneumonitis	37
First-in-human prospective trial of sonobiopsy in high-grade glioma patients using neuronavigation-guided focused ultrasound	37

Multi-omics machine learning to study host-microbiome interactions in early-onset colorectal cancer	37
Genomic and transcriptomic analyses identify distinctive features of triple-negative inflammatory breast cancer	37
Real-world experience of Molecular Tumour Boards for clinical decision-making for cancer patients	37
Shared evolutionary trajectories underlying carcinogenesis and metastasis in biliary tract cancer	37
An international multi-institutional validation study of the algorithm for prostate cancer detection and Gleason grading	37
A core driver gene set identified based on geMER reveals its potential driver mechanism in pan-cancer	36
Enhancing adoptive cell therapy: future strategies for immune cell radioprotection in neuro-oncology	36
Tumor fraction-based prognostic tool for cancer patients referred to early phase clinical trials	36
Glucocorticoid and mitophagy signaling–based molecular subtyping reveals HMGA1 as a prognostic and immunotherapy biomarker in lung adenocarcinoma	36
ML-based sequential analysis to assist selection between VMP and RD for newly diagnosed multiple myeloma	36
Clonal determinants of organotropism and survival in metastatic uveal melanoma	36
Author Correction: Imaging and AI based chromatin biomarkers for diagnosis and therapy evaluation from liquid biopsies	35
Validation of histopathology-based deep learning algorithms for detection of actionable non-small cell lung cancer biomarkers	35
Progress in personalized immunotherapy for patients with brain metastasis	35
Mediator kinase inhibition impedes transcriptional plasticity and prevents resistance to ERK/MAPK-targeted therapy in KRAS-mutant cancers	35
APOLLO11: a bio-data-driven model for clinical and translational research in lung cancer	35
Organ-metastatic landscape delineates overall and site-specific immune-related adverse events of PD-L1 blockade in advanced NSCLC	35
HER3 targeting augments the efficacy of panobinostat in claudin-low triple-negative breast cancer cells	34
Fibroblast-derived HSD11B1 deficiency drives lung cancer in never-smokers through steroid metabolic imbalance	34
Novel molecular subtypes of METex14 non-small cell lung cancer with distinct biological and clinical significance	34
Apatinib enhances anti-PD-1 efficacy by inhibiting Exo70-mediated exosome secretion in pMMR/MSS colorectal cancer	34
In-depth inference of transcriptional regulatory networks reveals NPM1 as a therapeutic ribosomal regulator in MYC-amplified medulloblastoma	34
Prediction of molecular subtypes from histology: AI-driven analysis of prostate cancer morphological patterns and therapeutic implications	34
Machine learning algorithms for predicting glioma patient prognosis based on CD163+FPR3+ macrophage signature	34
Selpercatinib combination with the mitochondria-targeted antioxidant MitoQ effectively suppresses RET–mutant thyroid cancer	34
The SMARCA4R1157W mutation facilitates chromatin remodeling and confers PRMT1/SMARCA4 inhibitors sensitivity in colorectal cancer	33
AI-driven eyelid tumor classification in ocular oncology using proteomic data	33
Translating spatial transcriptomic signatures in adenosquamous carcinoma into bulk prognostic biomarkers in lung adenocarcinoma: a bottom-up approach	33
The hegemonic EWSR1::ETS oncoprotein overrules core regulatory circuitry principles in Ewing sarcoma	33
Leveraging patient derived models of FGFR2 fusion positive intrahepatic cholangiocarcinoma to identify synergistic therapies	32
Compound heterozygous MSH3 germline variants and associated tumor somatic DNA mismatch repair dysfunction	32
Integrating liquid biopsy and mutational signatures to advance precision oncology	32
Prediction of homologous recombination deficiency identifies colorectal tumors sensitive to PARP inhibition	32
A large-scale, multi-centre validation study of an AI-empowered blood-based test for multi-cancer early detection	32
Targeting tumoral heterogeneity in lung cancer: a novel, CT-texture-guided targeted biopsy approach with exome sequencing	31
Multiclass machine learning models for molecular subtype identification of pediatric low-grade glioma using bi-institutional MRIs for precision medicine	31
ChemoID-guided therapy improves objective response rate in recurrent platinum-resistant ovarian cancer randomized clinical trial	31
High clinical actionability of a pan-cancer tissue-based combined DNA and RNA next generation sequencing assay in a diverse Asian population	31
EPAS1 increases SDHA to inhibit proliferation of multiple myeloma cells by restoring TCA Cycle	30
Colorectal cancer risk stratification on histological slides based on survival curves predicted by deep learning	30
Survival prediction and risk stratification in R0-resected ovarian cancer: a multi-modal deep learning approach	30
Potential of pre-diagnostic metabolomics for colorectal cancer risk assessment or early detection	30
Efficacy of PARP inhibitor therapy after targeted BRAF/MEK failure in advanced melanoma	29
Plasma proteomic biomarkers predict therapeutic responses in advanced biliary tract cancer patients receiving Camrelizumab plus the GEMOX treatment	29
CNTNAP4 signaling regulates osteosarcoma disease progression	29
Artificial intelligence-based epigenomic, transcriptomic and histologic signatures of tobacco use in oral squamous cell carcinoma	28
CDK4/6i reverse PARPi resistance by targeting the E2F1- MCM2/5 pathway	28
Clinical actionability in gliomas revealed by real-world next-generation sequencing: a multicentric study	28
Targeting WFS1 overcomes KRASG12D dependency and adaptive resistance to KRAS inhibition in pancreatic cancer	28
Multi-output prediction of dose–response curves enables drug repositioning and biomarker discovery	28
Homologous recombination deficiency signatures in gastrointestinal and thoracic cancers correlate with platinum therapy duration	28
Augmented reality microscopy to bridge trust between AI and pathologists	27
Optical genome mapping as a high-resolution tool for uncovering cytogenetic complex and cryptic alterations in a cohort of patients with MDS and AML	27
SLC25A1 upregulation promotes HNSCC cisplatin resistance via H3K27ac-mediated cellular senescence	27
SGI-7079 as a novel type I FLT3 inhibitor overcomes resistance to gilteritinib and quizartinib mediated by ITD and TKD mutations in acute myeloid leukemia	27
Treatment adherence and clinical outcomes of osimertinib in minority patients with advanced EGFR mutated NSCLC	27
Targeting high-risk MYC-overexpressed osteosarcoma with an Aurora kinase inhibitor:--results from a pilot umbrella trial	27
Artificial intelligence-based assessment of PD-L1 expression in diffuse large B cell lymphoma	26
Unlocking the potential of TIGIT in enhancing therapeutic strategies for acute myeloid leukemia through combined azacitidine therapy	26
Perfusion-based ex vivo culture of frozen ovarian cancer tissues with preserved tumor microenvironment	26
ASF1B promotes gastric cancer liver metastasis through inhibiting ZDHHC9/PCBP1/ SLC7A11 signaling axis mediated ferroptosis	26
The regulatory roles and therapeutic strategies of the solute carrier transporters in cancer metabolism	26
Deep learning-based quantification of eosinophils and lymphocytes shows complementary prognostic effects in colorectal cancer patients	26
Integrative pan-cancer and COAD-focused multi-omics analysis of non-histone acetylation substrate-related transcriptional landscapes	25
Cancer-related cells and oncosomes in the liquid biopsy of pancreatic cancer patients undergoing surgery	25
Personalized chronotherapy in glioblastoma: integrating circadian profiling and PK–PD modelling to optimize temozolomide timing	25
Deciphering the liver’s role in pancreatic cancer metastasis: pathways and therapeutic approaches	25
MDM2 inhibition is associated with the emergence of TP53-altered clonal hematopoiesis	25
Integration of radiomics, deep learning, transcriptomics, and metabolomics reveals prognostic risk stratification and underlying biological mechanisms in colorectal cancer	25
Fractal analysis of longitudinal MRI for predicting response to neoadjuvant chemotherapy in breast cancer	25
A complex phylogeny of lineage plasticity in metastatic castration resistant prostate cancer	25
Predicting ROS1 and ALK fusions in NSCLC from H&E slides with a two-step vision transformer approach	25
A multi-cancer early detection blood test using machine learning detects early-stage cancers lacking USPSTF-recommended screening	25
ALK fusions in the pan-cancer setting: another tumor-agnostic target?	24
Potential utility of risk stratification for multicancer screening with liquid biopsy tests	24
RICH1 enhances pro-inflammatory TAM infiltration in breast cancer via promoting TRIM21-mediated ubiquitination of RhoA and inhibiting STAT3 phosphorylation	24
Co-clinical trial targeting ER, FGFR and CDK4/6 in resistant hormone-positive breast cancer with FGFR alterations	24
Role of large language models in the multidisciplinary decision-making process for patients with renal cell carcinoma: a pilot experience	24
Author Correction: A targetable OSGIN1–AMPK–SLC2A3 axis controls the vulnerability of ovarian cancer to ferroptosis	24
Author Correction: HDAC6 facilitates LUAD progression by inducing EMT and enhancing macrophage polarization towards the M2 phenotype	24

A multimodal fusion system predicting survival benefits of immune checkpoint inhibitors in unresectable hepatocellular carcinoma	24
Complete morphologic response to gilteritinib in ALK-rearranged acute myeloid leukemia	24
APOE-high myeloid cells are uniquely associated with metastatic intrathoracic lymph nodes obtained by EBUS-TBNA in primary lung cancer	24
Mapping immunosuppressive terrain in high-grade serous ovarian cancer: tumor-intrinsic, stromal, and spatial drivers of therapy response	24
ACACA modulates R-loop homeostasis to enhance lipid metabolism and microenvironmental interactions in ccRCC	23
Multicenter radio-multiomic analysis for predicting breast cancer outcome and unravelling imaging-biological connection	23
Clock pathway inhibitor overcomes tumor immune-exclusion via regulation of fibrocyte differentiation	23
Ligand-receptor interactions combined with histopathology for improved prognostic modeling in HPV-negative head and neck squamous cell carcinoma	23
LINE1 insertion into the NACC2 locus disrupts the HDM2 axis and activates lung oncogenic signaling	23
HER2 expression in cervical squamous cell carcinoma: high prevalence of HER2-low/ultralow and spatiotemporal heterogeneity across tumor evolution	23
Predicting colorectal cancer survival by combined c-reactive protein and tumor immune score	23
Therapeutic vulnerabilities exposed by the 9p21 loss identified through multiparametric drug screening inform rational combination strategies	23
Patient-derived three-dimensional lung tumor models to evaluate response to therapy	23
ARHGAP4/MYH9/β-catenin/c-Jun positive feedback loop promotes colorectal cancer stemness	23
Ultrasensitive ctDNA monitoring for organ preservation in patients with locally advanced rectal cancer	23
Germline pathogenic variants in DNA repair pathways: a key feature in a significant subset of translocation-associated sarcomas	23
Deep learning-based spatiotemporal estimation of lesion changes for patient-level assessment of breast cancer lung metastases on longitudinal CT	23
Personalized circulating tumor DNA dynamics inform survival and response to immune checkpoint blockade in recurrent/metastatic head and neck cancer	22
SPOCK1 acts as a negative regulator of ferroptosis in non-small cell lung cancer	22
An integrated single-cell lung cancer atlas reveals distinct fibroblast phenotypes between adenocarcinoma and squamous cell carcinomas	22
Redefining therapeutic horizons in thymic epithelial tumors: precision, combinations, and emerging biology	22
Striking efficacy of a vaccine targeting TOP2A for triple-negative breast cancer immunoprevention	22
Functional cure with single agent olutasidenib in relapsed IDH1/NPM1 co-mutated AML	22
Personalized prediction of anticancer potential of non-oncology drugs through learning from genome derived molecular pathways	22
Metabolic transcriptomic subtyping defines distinct immunogenomic and clinical landscapes in non–small cell lung cancer	22
Genetic and oncogenic features of RASGRF fusions	22
Transcriptional profiling clarifies a program of enzalutamide extreme non-response in lethal prostate cancer	21
Use of PSMA PET/CT to detect prostate cancer metastatic to a preexisting thyroid nodule	21
PUM1-TRAF3 fusion protein activates non-canonical NF-κB signaling via rescued NIK in biliary tract cancer	21
Complete response to fifth-line anti-PD-1 rechallenge in fumarate hydratase-mutated papillary renal cell carcinoma	21
Chemokine expression predicts T cell-inflammation and improved survival with checkpoint inhibition across solid cancers	21
Comprehensive characterization and targeted treatment of a pediatric epithelioid glioblastoma with a rare TRIM24-NTRK2 fusion	21
Development and interpretation of a multimodal predictive model for prognosis of gastrointestinal stromal tumor	21
Bladder cancer diagnostic and prognostic models from DNA methylation by multi algorithm machine learning	20
COL3A1high cancer-associated fibroblasts orchestrate metabolic and immune microenvironments to confer chemoresistance in breast cancer	20
Novel paediatric case of a spinal high-grade astrocytoma with piloid features in a patient with Noonan Syndrome	20
Validation of QuANTUM-derived tumor cell fraction for molecular testing in high-grade serous tubo-ovarian carcinoma	20
Real life outcome analysis of breast cancer brain metastases treated with Trastuzumab Deruxtecan	20
NCT/DKFZ MASTER handbook of interpreting whole-genome, transcriptome, and methylome data for precision oncology	20
Multimodal fusion of pathology and radiology foundation models for WHO 2021 glioma subtyping	20
Author Correction: Predicting the tumor microenvironment composition and immunotherapy response in non-small cell lung cancer from digital histopathology images	20
GZMK expression within activated intratumoral T-cell subsets reflects differentiation efficiency and predicts response to cancer immunotherapy	20
Machine learning-driven multi-targeted drug discovery in colon cancer using biomarker signatures	20
Dynamic alterations in the irradiated draining lymph node	20
Deepath-SCC: a deep learning model for accurate tissue origin identification in squamous cell carcinoma	20
Predicting survival in prospective clinical trials using weakly-supervised QSP	20
Evaluating cell culture reliability in pediatric brain tumor primary cells through DNA methylation profiling	20
Targeting histone deacetylation, cell cycle regulators and heat shock proteins as novel therapeutic strategies for penile cancers	20
Impact of TP53 mutations in Triple Negative Breast Cancer	20
Survival outcomes with matched targeted therapy in advanced biliary tract cancer: a large global cohort analysis	20
Deep learning-based segmentation and subtype prediction of renal cell carcinoma on contrast-enhanced CT	19
Whole-genome analysis of an aggressive metastatic pancreatic solid pseudopapillary neoplasm	19
A review of machine learning methods for cancer characterization from microbiome data	19
Design of self-assembled micelles based on natural dual-targeting strategies and evaluation of their anti-liver cancer effects as drug delivery systems	19
Development of potent antibody drug conjugates against ICAM1+ cancer cells in preclinical models of cholangiocarcinoma	19
GD2: hopes and challenges for the treatment of pediatric patients with tumors of the central nervous system	19
Tertiary lymphoid structures potentially promote immune checkpoint inhibitor response in SMARCB1-deficient medullary renal cell carcinoma	19
The drug efficacy testing in 3D cultures platform identifies effective drugs for ovarian cancer patients	19
Multi-omics analyses reveal interactions between GREM1+ fibroblasts and SPP1+ macrophages in gastric cancer	19
Opportunities and challenges for patient-derived models of brain tumors in functional precision medicine	19
AI-driven multi-omics integration of cancer-associated fibroblasts for prognostic modeling and therapeutic target discovery in head and neck squamous cell carcinoma	19
A destabilizing Y891D mutation in activated EGFR impairs sensitivity to kinase inhibition	18
Integrative analysis of KEAP1/NFE2L2 alterations across 3600+ tumors reveals an NRF2 expression signature as a prognostic biomarker in cancer	18
Spatially defined IGF1R-STMN1 axis delineates a metastatic cell state in osteosarcoma	18
A comprehensive analysis of minimally differentially methylated regions common to pediatric and adult solid tumors	18
Exceptional response to the ATR inhibitor, camonsertib, in a patient with ALT+ metastatic melanoma	18
HDAC6 facilitates LUAD progression by inducing EMT and enhancing macrophage polarization towards the M2 phenotype	18
DNA methylation at quantitative trait loci (mQTLs) varies with cell type and nonheritable factors and may improve breast cancer risk assessment	18
The next layer: augmenting foundation models with structure-preserving and attention-guided learning for local patches to global context awareness in computational pathology	18
Tackling FGFR3-driven bladder cancer with a promising synergistic FGFR/HDAC targeted therapy	18
Progress and challenges of artificial intelligence in lung cancer clinical translation	18
Integrative molecular analyses define correlates of high B7-H3 expression in metastatic castrate-resistant prostate cancer	18
Single-cell transcriptome sequencing reveals spatial distribution of IL34+ cancer-associated fibroblasts in hepatocellular carcinoma tumor microenvironment	17
Integrative whole slide image and spatial transcriptomics analysis with QuST and QuPath	17
Plasma epigenomic profiling reveals treatment-emergent squamous transformation in prostate cancer	17
Plasma cell-free DNA methylation-based prognosis in metastatic castrate-resistant prostate cancer	17
Detection and classification of lymphoma from cell-free methylome data	17
Biallelic EPCAM deletions induce tissue-specific DNA repair deficiency and cancer predisposition	17
Integrative immune subtyping of HNSCC reveals clinically relevant phenotypes and treatment-associated transitions	17
Towards precision radiation oncology: endocrine therapy response as a biomarker for personalization of breast radiotherapy	17
Mass spectrometry-based proteomics delivers in-depth proteome profiling of FFPE lung cancer biopsies from single glass slides	17
Large scale quantification of natural killer cell-induced apoptosis in patient-derived organoids reveals intratumoral response heterogeneity	17
Deep learning-based detection and semi-quantitative model for spread through air spaces (STAS) in lung adenocarcinoma	16
Element-specific estimation of background mutation rates in whole cancer genomes through transfer learning	16
Spatial tumor immune microenvironment phenotypes in ovarian cancer	16
Fast, accurate, and racially unbiased pan-cancer tumor-only variant calling with tabular machine learning	16
Multi-omics analysis reveals NNMT as a master metabolic regulator of metastasis in esophageal squamous cell carcinoma	16
Secrets of DNA-PKcs beyond DNA repair	16
Liquid-liquid phase separation of CBX2 regulates lipid raft-mediated extracellular vesicle biogenesis to facilitate ovarian carcinoma metastasis	16
Prediction and analysis of tumor infiltrating lymphocytes across 28 cancers by TILScout using deep learning	16
Defining the extracellular matrix for targeted immunotherapy in adult and pediatric brain cancer	16
Precision immuno-oncology approach for four malignant tumors in siblings with constitutional mismatch repair deficiency syndrome	16
Multimodal spatial proteomic profiling in acute myeloid leukemia	16
Valproic acid reverses macrophage-mediated temozolomide resistance in macrophage-rich gliomas	16
Integration of pre-treatment computational radiomics, deep radiomics, and transcriptomics enhances soft-tissue sarcoma patient prognosis	16