npj Precision Oncology

Papers
(The TQCC of npj Precision Oncology is 12. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)
ArticleCitations
KMT2C inactivation leads to PTEN downregulation and tolerance to DNA damage during cell cycle progression472
MYSM1 promotes lung adenocarcinoma progression via TRAF2/3-mediated activation of MAPK and non-canonical NF-κB pathways252
The dynamic immune behavior of primary and metastatic ovarian carcinoma176
Circulating tumor DNA in ALK-positive anaplastic large cell lymphoma: a proof-of-concept study175
Exosome- transported FER inhibitor suppresses progression of diffuse large B-cell lymphoma via regulating AJUBA/Hippo axis163
BRAF v600E–mutant cancers treated with vemurafenib alone or in combination with everolimus, sorafenib, or crizotinib or with paclitaxel and carboplatin (VEM-PLUS) study156
A protein-encoding CCDC7 circular RNA inhibits the progression of prostate cancer by up-regulating FLRT3150
Artificial intelligence-driven prediction of lymph node metastasis in T1 esophageal squamous cell carcinoma using whole slide images138
Grading of lung adenocarcinomas with simultaneous segmentation by artificial intelligence (GLASS-AI)125
Constitutional mismatch repair deficiency mimicking Lynch syndrome is associated with hypomorphic mismatch repair gene variants109
AI-enabled single-cell dissection of the palmitoylation landscape identifies a multicellular prognostic program in gastric cancer109
Genome-wide analyses reveals an association between invasive urothelial carcinoma in the Shetland sheepdog and NIPAL1105
Developing survival prediction models in colorectal cancer using epigenome-wide DNA methylation data from whole blood103
Author Correction: An automated deep learning pipeline for EMVI classification and response prediction of rectal cancer using baseline MRI: a multi-centre study89
Therapeutic responses in patients with advanced NSCLC enrolled in early-phase clinical trials at MD Anderson79
High-throughput screening identifies NT-1 that synergizes with MRTX1133 against acquired resistant KRASG12D colorectal cancer78
A perspective on life-cycle health technology assessment and real-world evidence for precision oncology in Canada78
Analyses of canine cancer mutations and treatment outcomes using real-world clinico-genomics data of 2119 dogs76
Tumor break load quantitates structural variant-associated genomic instability with biological and clinical relevance across cancers74
Deciphering brain metastasis in epithelial ovarian cancer: multimodal analysis and potential biomarkers73
Spatial transcriptomics reveals molecular heterogeneity and subtype-specific therapeutic targets in small cell lung cancer70
Single nuclei and spatial profiling of sacrococcygeal teratomas reveals cellular composition and X inactivation heterogeneity69
Interferon signaling and ferroptosis in tumor immunology and therapy69
Development and testing of a polygenic risk score for breast cancer aggressiveness69
Sub-regional radiomics combining multichannel 2-dimensional or 3-dimensional deep learning for predicting neoadjuvant chemo-immunotherapy response in esophageal squamous cell carcinoma: a multicenter 67
A multi-center study on the consistency of drug sensitivity testing in patients with acute myeloid leukemia67
Patient-level proteomic network prediction by explainable artificial intelligence66
Benchmarking progression-free survival ratio as primary endpoint in precision oncology clinical trials65
Multi-modal characterization of metabolic and immune gene clusters in adrenocortical carcinoma treatment65
Robust multicentre detection and classification of colorectal liver metastases on CT: application of foundation models63
Assessment of TROP2, CEACAM5 and DLL3 in metastatic prostate cancer: Expression landscape and molecular correlates62
Complement activation in tumor microenvironment after neoadjuvant therapy and its impact on pancreatic cancer outcomes60
Mucin-1: a promising pan-cancer therapeutic target60
Improved prediction of MAPKi response duration in melanoma patients using genomic data and machine learning59
Imaging and AI based chromatin biomarkers for diagnosis and therapy evaluation from liquid biopsies58
Development of a translational murine model for antibody-drug conjugate-induced interstitial lung disease58
Co-targeting KRAS G12C and EGFR reduces both mutant and wild-type RAS-GTP58
An automated deep learning pipeline for EMVI classification and response prediction of rectal cancer using baseline MRI: a multi-centre study58
Barriers and opportunities in pancreatic cancer immunotherapy56
User-centered design approach to visualize PROMs for molecular tumor boards53
Prospective implementation of an aqueous humor liquid biopsy platform informs clinical diagnosis and management of retinoblastoma and other intraocular lesions53
Enhanced efficacy of ipilimumab plus nivolumab in angiogenic subtypes of metastatic clear-cell renal cell carcinoma51
Venetoclax resistance in preclinical KMT2A-rearranged acute lymphoblastic leukemia models is characterized by high inter- and intra-model heterogeneity50
PD-1 blockade potentiates neoadjuvant chemotherapy in NSCLC via increasing CD127+ and KLRG1+ CD8 T cells50
Establishing predictive machine learning models for drug responses in patient derived cell culture49
Pan-cancer molecular tumor board experience with biomarker-driven precision immunotherapy48
Discovery of prognostic lncRNAs in colorectal cancer using spatial transcriptomics48
Real-world experience of Molecular Tumour Boards for clinical decision-making for cancer patients48
Translational feasibility of a plasmonic microarray–based liquid biopsy for KRAS codon mutation detection across tissue, plasma, and urine in early colorectal cancer46
Multi-omics machine learning to study host-microbiome interactions in early-onset colorectal cancer45
Baseline biomarkers of efficacy and on-treatment immune-profile changes associated with bempegaldesleukin plus nivolumab45
Prolonged response to dual immune checkpoint blockade in patients with advanced solid tumors: a case series44
TRIM65 regulates glucose metabolic reprogramming to promote glioma cell proliferation via ubiquitination and degradation of AMPK44
Machine learning model for predicting tertiary lymphoid structures and treatment response in triple-negative breast cancer44
AI-driven body composition atlas reveals its association with NSCLC immunotherapy outcome and molecular background: a multicenter study43
Erigoster B targeting DECR1 induces ferroptosis of breast cancer cells via promoting phosphatidylcholine/arachidonic acid metabolism42
Stage-dependent spatial distribution and prognostic value of CD8+ tissue-resident memory T cells in NSCLC42
An international multi-institutional validation study of the algorithm for prostate cancer detection and Gleason grading42
Comparative cost analysis of a diagnostic multi-omics platform for decision support in advanced cancer – results from the Tumor Profiler Melanoma project41
Targeting Nrf2/PHKG2 axis to enhance radiosensitivity in NSCLC40
Personalized signaling pathway analysis of gastrointestinal tumors for patient stratification and drug target evaluation using clinically derived core biopsies40
Multiregional transcriptomic profiling provides improved prognostic insight in localized non-small cell lung cancer40
Collagen disorder architecture features are associated with clinical, molecular, genetic factors and survival outcomes in colon cancer40
Self-supervised attention-based deep learning for pan-cancer mutation prediction from histopathology39
m6A reader IGF2BP2-stabilized lncRNA LHX1-DT inhibits renal cell carcinoma (RCC) cell proliferation and invasion by sponging miR-590-5p39
Single-cell landscape of bronchoalveolar immune cells in patients with immune checkpoint inhibitor-related pneumonitis38
Relationship among DDR gene mutations, TMB and PD-L1 in solid tumour genomes identified using clinically actionable biomarker assays38
Histological transformation to gliosarcoma with combined BRAF/MEK inhibition in BRAF V600E mutated glioblastoma38
A universal immunohistochemistry analyzer for generalizing AI-driven assessment of immunohistochemistry across immunostains and cancer types37
ECM-based molecular subtypes define prognostic, EMT status, and therapeutic diversity in IDH-mutant gliomas37
Single-cell analysis identifies dysregulated cell type-specific gene programs and intercellular crosstalk underlying colorectal cancer37
Genomic and transcriptomic analyses identify distinctive features of triple-negative inflammatory breast cancer37
First-in-human prospective trial of sonobiopsy in high-grade glioma patients using neuronavigation-guided focused ultrasound36
Author Correction: Imaging and AI based chromatin biomarkers for diagnosis and therapy evaluation from liquid biopsies36
A core driver gene set identified based on geMER reveals its potential driver mechanism in pan-cancer36
Novel molecular subtypes of METex14 non-small cell lung cancer with distinct biological and clinical significance36
The hegemonic EWSR1::ETS oncoprotein overrules core regulatory circuitry principles in Ewing sarcoma36
Prediction of molecular subtypes from histology: AI-driven analysis of prostate cancer morphological patterns and therapeutic implications35
Deciphering associations between three RNA splicing-related genetic variants and lung cancer risk35
AI-driven eyelid tumor classification in ocular oncology using proteomic data35
ML-based sequential analysis to assist selection between VMP and RD for newly diagnosed multiple myeloma35
APOLLO11: a bio-data-driven model for clinical and translational research in lung cancer35
Integrating liquid biopsy and mutational signatures to advance precision oncology35
Mediator kinase inhibition impedes transcriptional plasticity and prevents resistance to ERK/MAPK-targeted therapy in KRAS-mutant cancers34
Selpercatinib combination with the mitochondria-targeted antioxidant MitoQ effectively suppresses RET–mutant thyroid cancer34
Clonal determinants of organotropism and survival in metastatic uveal melanoma34
In-depth inference of transcriptional regulatory networks reveals NPM1 as a therapeutic ribosomal regulator in MYC-amplified medulloblastoma34
Prediction of homologous recombination deficiency identifies colorectal tumors sensitive to PARP inhibition34
A large-scale, multi-centre validation study of an AI-empowered blood-based test for multi-cancer early detection33
Progress in personalized immunotherapy for patients with brain metastasis33
Validation of histopathology-based deep learning algorithms for detection of actionable non-small cell lung cancer biomarkers32
Tumor fraction-based prognostic tool for cancer patients referred to early phase clinical trials32
Apatinib enhances anti-PD-1 efficacy by inhibiting Exo70-mediated exosome secretion in pMMR/MSS colorectal cancer32
Organ-metastatic landscape delineates overall and site-specific immune-related adverse events of PD-L1 blockade in advanced NSCLC32
The SMARCA4R1157W mutation facilitates chromatin remodeling and confers PRMT1/SMARCA4 inhibitors sensitivity in colorectal cancer32
Fibroblast-derived HSD11B1 deficiency drives lung cancer in never-smokers through steroid metabolic imbalance32
Leveraging patient derived models of FGFR2 fusion positive intrahepatic cholangiocarcinoma to identify synergistic therapies32
Compound heterozygous MSH3 germline variants and associated tumor somatic DNA mismatch repair dysfunction32
Translating spatial transcriptomic signatures in adenosquamous carcinoma into bulk prognostic biomarkers in lung adenocarcinoma: a bottom-up approach32
Enhancing adoptive cell therapy: future strategies for immune cell radioprotection in neuro-oncology31
Multiclass machine learning models for molecular subtype identification of pediatric low-grade glioma using bi-institutional MRIs for precision medicine31
Machine learning algorithms for predicting glioma patient prognosis based on CD163+FPR3+ macrophage signature31
HER3 targeting augments the efficacy of panobinostat in claudin-low triple-negative breast cancer cells31
Treatment adherence and clinical outcomes of osimertinib in minority patients with advanced EGFR mutated NSCLC30
High clinical actionability of a pan-cancer tissue-based combined DNA and RNA next generation sequencing assay in a diverse Asian population30
A complex phylogeny of lineage plasticity in metastatic castration resistant prostate cancer30
Targeting tumoral heterogeneity in lung cancer: a novel, CT-texture-guided targeted biopsy approach with exome sequencing29
Unlocking the potential of TIGIT in enhancing therapeutic strategies for acute myeloid leukemia through combined azacitidine therapy29
Artificial intelligence-based epigenomic, transcriptomic and histologic signatures of tobacco use in oral squamous cell carcinoma29
Potential of pre-diagnostic metabolomics for colorectal cancer risk assessment or early detection29
EPAS1 increases SDHA to inhibit proliferation of multiple myeloma cells by restoring TCA Cycle29
Clinical actionability in gliomas revealed by real-world next-generation sequencing: a multicentric study29
Optical genome mapping as a high-resolution tool for uncovering cytogenetic complex and cryptic alterations in a cohort of patients with MDS and AML29
Fractal analysis of longitudinal MRI for predicting response to neoadjuvant chemotherapy in breast cancer29
Survival prediction and risk stratification in R0-resected ovarian cancer: a multi-modal deep learning approach29
Activation of CD44/PAK1/AKT signaling promotes resistance to FGFR1 inhibition in squamous-cell lung cancer29
A patient-designed tissue-engineered model of the infiltrative glioblastoma microenvironment28
Predicting ROS1 and ALK fusions in NSCLC from H&E slides with a two-step vision transformer approach28
Perfusion-based ex vivo culture of frozen ovarian cancer tissues with preserved tumor microenvironment28
ASF1B promotes gastric cancer liver metastasis through inhibiting ZDHHC9/PCBP1/ SLC7A11 signaling axis mediated ferroptosis28
CDK4/6i reverse PARPi resistance by targeting the E2F1- MCM2/5 pathway27
Deep learning-based quantification of eosinophils and lymphocytes shows complementary prognostic effects in colorectal cancer patients27
Homologous recombination deficiency signatures in gastrointestinal and thoracic cancers correlate with platinum therapy duration27
ChemoID-guided therapy improves objective response rate in recurrent platinum-resistant ovarian cancer randomized clinical trial27
Multi-output prediction of dose–response curves enables drug repositioning and biomarker discovery26
Personalized chronotherapy in glioblastoma: integrating circadian profiling and PK–PD modelling to optimize temozolomide timing26
Integration of radiomics, deep learning, transcriptomics, and metabolomics reveals prognostic risk stratification and underlying biological mechanisms in colorectal cancer26
MDM2 inhibition is associated with the emergence of TP53-altered clonal hematopoiesis26
Colorectal cancer risk stratification on histological slides based on survival curves predicted by deep learning26
Deciphering the liver’s role in pancreatic cancer metastasis: pathways and therapeutic approaches25
Efficacy of PARP inhibitor therapy after targeted BRAF/MEK failure in advanced melanoma25
A multi-cancer early detection blood test using machine learning detects early-stage cancers lacking USPSTF-recommended screening25
The regulatory roles and therapeutic strategies of the solute carrier transporters in cancer metabolism25
Targeting high-risk MYC-overexpressed osteosarcoma with an Aurora kinase inhibitor:--results from a pilot umbrella trial25
CNTNAP4 signaling regulates osteosarcoma disease progression25
ALK fusions in the pan-cancer setting: another tumor-agnostic target?25
Plasma proteomic biomarkers predict therapeutic responses in advanced biliary tract cancer patients receiving Camrelizumab plus the GEMOX treatment24
A multimodal fusion system predicting survival benefits of immune checkpoint inhibitors in unresectable hepatocellular carcinoma24
Personalized prediction of anticancer potential of non-oncology drugs through learning from genome derived molecular pathways24
Chemokine expression predicts T cell-inflammation and improved survival with checkpoint inhibition across solid cancers24
RICH1 enhances pro-inflammatory TAM infiltration in breast cancer via promoting TRIM21-mediated ubiquitination of RhoA and inhibiting STAT3 phosphorylation24
SLC25A1 upregulation promotes HNSCC cisplatin resistance via H3K27ac-mediated cellular senescence24
Artificial intelligence-based assessment of PD-L1 expression in diffuse large B cell lymphoma24
Complete morphologic response to gilteritinib in ALK-rearranged acute myeloid leukemia24
Germline pathogenic variants in DNA repair pathways: a key feature in a significant subset of translocation-associated sarcomas24
Transcriptional profiling clarifies a program of enzalutamide extreme non-response in lethal prostate cancer24
Augmented reality microscopy to bridge trust between AI and pathologists24
Role of large language models in the multidisciplinary decision-making process for patients with renal cell carcinoma: a pilot experience24
Cancer-related cells and oncosomes in the liquid biopsy of pancreatic cancer patients undergoing surgery24
Genetic and oncogenic features of RASGRF fusions24
APOE-high myeloid cells are uniquely associated with metastatic intrathoracic lymph nodes obtained by EBUS-TBNA in primary lung cancer24
PUM1-TRAF3 fusion protein activates non-canonical NF-κB signaling via rescued NIK in biliary tract cancer23
LINE1 insertion into the NACC2 locus disrupts the HDM2 axis and activates lung oncogenic signaling23
Author Correction: HDAC6 facilitates LUAD progression by inducing EMT and enhancing macrophage polarization towards the M2 phenotype23
Therapeutic vulnerabilities exposed by the 9p21 loss identified through multiparametric drug screening inform rational combination strategies23
Mapping immunosuppressive terrain in high-grade serous ovarian cancer: tumor-intrinsic, stromal, and spatial drivers of therapy response23
ARHGAP4/MYH9/β-catenin/c-Jun positive feedback loop promotes colorectal cancer stemness22
Predicting colorectal cancer survival by combined c-reactive protein and tumor immune score22
Functional cure with single agent olutasidenib in relapsed IDH1/NPM1 co-mutated AML22
ACACA modulates R-loop homeostasis to enhance lipid metabolism and microenvironmental interactions in ccRCC21
HER2 expression in cervical squamous cell carcinoma: high prevalence of HER2-low/ultralow and spatiotemporal heterogeneity across tumor evolution21
SPOCK1 acts as a negative regulator of ferroptosis in non-small cell lung cancer21
Striking efficacy of a vaccine targeting TOP2A for triple-negative breast cancer immunoprevention21
Personalized circulating tumor DNA dynamics inform survival and response to immune checkpoint blockade in recurrent/metastatic head and neck cancer21
Ligand-receptor interactions combined with histopathology for improved prognostic modeling in HPV-negative head and neck squamous cell carcinoma21
Author Correction: A targetable OSGIN1–AMPK–SLC2A3 axis controls the vulnerability of ovarian cancer to ferroptosis21
Potential utility of risk stratification for multicancer screening with liquid biopsy tests20
Clock pathway inhibitor overcomes tumor immune-exclusion via regulation of fibrocyte differentiation20
Complete response to fifth-line anti-PD-1 rechallenge in fumarate hydratase-mutated papillary renal cell carcinoma20
Author Correction: Predicting the tumor microenvironment composition and immunotherapy response in non-small cell lung cancer from digital histopathology images20
Use of PSMA PET/CT to detect prostate cancer metastatic to a preexisting thyroid nodule20
Predicting survival in prospective clinical trials using weakly-supervised QSP20
Comprehensive characterization and targeted treatment of a pediatric epithelioid glioblastoma with a rare TRIM24-NTRK2 fusion20
Development and interpretation of a multimodal predictive model for prognosis of gastrointestinal stromal tumor20
Multicenter radio-multiomic analysis for predicting breast cancer outcome and unravelling imaging-biological connection20
Co-clinical trial targeting ER, FGFR and CDK4/6 in resistant hormone-positive breast cancer with FGFR alterations20
Multimodal fusion of pathology and radiology foundation models for WHO 2021 glioma subtyping20
AI-driven multi-omics integration of cancer-associated fibroblasts for prognostic modeling and therapeutic target discovery in head and neck squamous cell carcinoma20
An integrated single-cell lung cancer atlas reveals distinct fibroblast phenotypes between adenocarcinoma and squamous cell carcinomas20
Exceptional response to the ATR inhibitor, camonsertib, in a patient with ALT+ metastatic melanoma20
Ultrasensitive ctDNA monitoring for organ preservation in patients with locally advanced rectal cancer20
Integrative analysis of KEAP1/NFE2L2 alterations across 3600+ tumors reveals an NRF2 expression signature as a prognostic biomarker in cancer20
Whole-genome analysis of an aggressive metastatic pancreatic solid pseudopapillary neoplasm20
Real life outcome analysis of breast cancer brain metastases treated with Trastuzumab Deruxtecan19
The drug efficacy testing in 3D cultures platform identifies effective drugs for ovarian cancer patients19
Tertiary lymphoid structures potentially promote immune checkpoint inhibitor response in SMARCB1-deficient medullary renal cell carcinoma19
HDAC6 facilitates LUAD progression by inducing EMT and enhancing macrophage polarization towards the M2 phenotype19
Deepath-SCC: a deep learning model for accurate tissue origin identification in squamous cell carcinoma19
GD2: hopes and challenges for the treatment of pediatric patients with tumors of the central nervous system19
Bladder cancer diagnostic and prognostic models from DNA methylation by multi algorithm machine learning19
Multi-omics analyses reveal interactions between GREM1+ fibroblasts and SPP1+ macrophages in gastric cancer19
Targeting histone deacetylation, cell cycle regulators and heat shock proteins as novel therapeutic strategies for penile cancers19
Development of potent antibody drug conjugates against ICAM1+ cancer cells in preclinical models of cholangiocarcinoma19
GZMK expression within activated intratumoral T-cell subsets reflects differentiation efficiency and predicts response to cancer immunotherapy19
Evaluating cell culture reliability in pediatric brain tumor primary cells through DNA methylation profiling19
Tackling FGFR3-driven bladder cancer with a promising synergistic FGFR/HDAC targeted therapy18
Opportunities and challenges for patient-derived models of brain tumors in functional precision medicine18
Validation of QuANTUM-derived tumor cell fraction for molecular testing in high-grade serous tubo-ovarian carcinoma18
Impact of TP53 mutations in Triple Negative Breast Cancer18
Progress and challenges of artificial intelligence in lung cancer clinical translation18
Novel paediatric case of a spinal high-grade astrocytoma with piloid features in a patient with Noonan Syndrome18
Machine learning-driven multi-targeted drug discovery in colon cancer using biomarker signatures18
NCT/DKFZ MASTER handbook of interpreting whole-genome, transcriptome, and methylome data for precision oncology18
COL3A1high cancer-associated fibroblasts orchestrate metabolic and immune microenvironments to confer chemoresistance in breast cancer18
Design of self-assembled micelles based on natural dual-targeting strategies and evaluation of their anti-liver cancer effects as drug delivery systems18
Survival outcomes with matched targeted therapy in advanced biliary tract cancer: a large global cohort analysis18
Large scale quantification of natural killer cell-induced apoptosis in patient-derived organoids reveals intratumoral response heterogeneity17
Precision immuno-oncology approach for four malignant tumors in siblings with constitutional mismatch repair deficiency syndrome17
Deep learning-based detection and semi-quantitative model for spread through air spaces (STAS) in lung adenocarcinoma17
Integrative molecular analyses define correlates of high B7-H3 expression in metastatic castrate-resistant prostate cancer17
A review of machine learning methods for cancer characterization from microbiome data17
Biallelic EPCAM deletions induce tissue-specific DNA repair deficiency and cancer predisposition17
Comprehensive genetic profiling and molecularly guided treatment for patients with primary CNS tumors17
An appraisal of genetic testing for prostate cancer susceptibility17
A comprehensive analysis of minimally differentially methylated regions common to pediatric and adult solid tumors17
DNA methylation at quantitative trait loci (mQTLs) varies with cell type and nonheritable factors and may improve breast cancer risk assessment17
Valproic acid reverses macrophage-mediated temozolomide resistance in macrophage-rich gliomas17
A destabilizing Y891D mutation in activated EGFR impairs sensitivity to kinase inhibition17
Plasma cell-free DNA methylation-based prognosis in metastatic castrate-resistant prostate cancer17
Pre-radiotherapy ctDNA liquid biopsy for risk stratification of oligometastatic non-small cell lung cancer17
The next layer: augmenting foundation models with structure-preserving and attention-guided learning for local patches to global context awareness in computational pathology16
Element-specific estimation of background mutation rates in whole cancer genomes through transfer learning16
Prediction and analysis of tumor infiltrating lymphocytes across 28 cancers by TILScout using deep learning16
Integrative whole slide image and spatial transcriptomics analysis with QuST and QuPath16
Towards precision radiation oncology: endocrine therapy response as a biomarker for personalization of breast radiotherapy16
Modeling glioblastoma relapse in vitro: a critical journey from 2D models to organ-on-chip alternatives16
Fast, accurate, and racially unbiased pan-cancer tumor-only variant calling with tabular machine learning16
Single-cell transcriptome analysis identifies MIF as a novel tumor-associated neutrophil marker for pancreatic ductal adenocarcinoma16
Secrets of DNA-PKcs beyond DNA repair16
Single-cell transcriptome sequencing reveals spatial distribution of IL34+ cancer-associated fibroblasts in hepatocellular carcinoma tumor microenvironment16
A phase II trial of mTORC1/2 inhibition in STK11 deficient non small cell lung cancer16
Integrative immune subtyping of HNSCC reveals clinically relevant phenotypes and treatment-associated transitions16
Liquid-liquid phase separation of CBX2 regulates lipid raft-mediated extracellular vesicle biogenesis to facilitate ovarian carcinoma metastasis16
Mass spectrometry-based proteomics delivers in-depth proteome profiling of FFPE lung cancer biopsies from single glass slides16
Multi-omics analysis deciphers intercellular communication regulating oxidative stress to promote oral squamous cell carcinoma progression16
Defining the extracellular matrix for targeted immunotherapy in adult and pediatric brain cancer15
Latent class analysis-derived classification improves the cancer-specific death stratification of molecular subtyping in colorectal cancer15
Emerging innovations in theranostics for pancreatic neuroendocrine tumors15
HAPIR: a refined Hallmark gene set-based machine learning approach for predicting immunotherapy response in cancer patients15
Trans-ancestry transcriptome-wide association and functional studies to uncover novel susceptibility genes and therapeutic targets for colorectal cancer15
Survival-inferred fragility of statistical significance in phase III oncology trials15
Integrating histopathology and transcriptomics for spatial tumor microenvironment profiling in a melanoma case study15
GLMP promotes EGFR-TKI resistance by activating autophagy and RhoA pathway in non-small cell lung cancer15
High risk clear cell renal cell carcinoma microenvironments contain protumour immunophenotypes lacking specific immune checkpoints15
CAR-macrophages in solid tumors: promise, progress, and prospects15
Spatial tumor immune microenvironment phenotypes in ovarian cancer15
Author Correction: Naltriben promotes tumor growth by activating the TRPM7-mediated development of the anti-inflammatory M2 phenotype15
Identification of novel prognostic and predictive biomarkers in salivary duct carcinoma via comprehensive molecular profiling15
Methylation cytometric pretreatment blood immune profiles with tumor mutation burden as prognostic indicators for survival outcomes in head and neck cancer patients on anti-PD-1 therapy15
Author Correction: An interpretable machine learning system for colorectal cancer diagnosis from pathology slides15
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