Nature Reviews Chemistry

(The TQCC of Nature Reviews Chemistry is 40. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-04-01 to 2024-04-01.)
Towards the sustainable discovery and development of new antibiotics448
Phase engineering of nanomaterials445
MXene chemistry, electrochemistry and energy storage applications443
Biomimetic peptide self-assembly for functional materials426
Haemostatic materials for wound healing applications385
Late-stage C–H functionalization offers new opportunities in drug discovery343
Recent advances in the chemistry and applications of N-heterocyclic carbenes291
Highlights and challenges in the selective reduction of carbon dioxide to methanol262
Exploiting chemistry and molecular systems for quantum information science251
Circularly polarized lanthanide luminescence for advanced security inks247
Metal–organic cages for molecular separations235
The concept of active site in heterogeneous catalysis224
Stabilization strategies in biomass depolymerization using chemical functionalization217
Exploring chemical compound space with quantum-based machine learning188
Water at charged interfaces188
The many flavours of mechanochemistry and its plausible conceptual underpinnings182
The principles, design and applications of fused-ring electron acceptors173
Radical philicity and its role in selective organic transformations170
Iron and manganese oxo complexes, oxo wall and beyond169
Nuclease resistance of DNA nanostructures165
A comparison of RAFT and ATRP methods for controlled radical polymerization158
Synthesis and applications of anisotropic nanoparticles with precisely defined dimensions158
Advances and opportunities in the exciting world of azobenzenes157
Molecular reactions at aqueous interfaces152
Dual-locked spectroscopic probes for sensing and therapy145
Wearable chemical sensors for biomarker discovery in the omics era143
A unified view on catalytic conversion of biomass and waste plastics139
Metals to combat antimicrobial resistance134
Temporary or removable directing groups enable activation of unstrained C–C bonds128
Bifunctional reagents in organic synthesis124
Charge-transfer processes in metal complexes enable luminescence and memory functions123
Natural and synthetic carbohydrate-based vaccine adjuvants and their mechanisms of action121
Bimetallic cooperation across the periodic table120
Developing bioorthogonal probes to span a spectrum of reactivities120
Deciphering protein post-translational modifications using chemical biology tools119
Chemistry under high pressure117
Chemical syntheses of bioinspired and biomimetic polymers toward biobased materials116
Construction of C–N bonds from small-molecule precursors through heterogeneous electrocatalysis112
Molecular excited states through a machine learning lens108
Nitrene transfer catalysts for enantioselective C–N bond formation107
Helical polymers for biological and medical applications104
Self-assembled inorganic chiral superstructures104
Sulfonyl fluorides as targets and substrates in the development of new synthetic methods101
Graphene oxide for photonics, electronics and optoelectronics101
Towards artificial molecular factories from framework-embedded molecular machines99
Fluorescent amino acids as versatile building blocks for chemical biology98
Biosynthesis of inorganic nanomaterials using microbial cells and bacteriophages97
Emerging chemistries and molecular designs for flow batteries97
Structural transformations of solid electrocatalysts and photocatalysts95
Designing disorder into crystalline materials95
Re-examining Fenton and Fenton-like reactions94
From self-replication to replicator systems en route to de novo life92
Organic reactivity from mechanism to machine learning91
Designing bioresponsive nanomaterials for intracellular self-assembly89
A practical guide to electrosynthesis86
Imine and imine-derived linkages in two-dimensional covalent organic frameworks86
Chemical approaches to cryopreservation83
Radical C(sp3)–H functionalization and cross-coupling reactions80
Taking phototherapeutics from concept to clinical launch78
Inhibition of RNA-binding proteins with small molecules77
NMR spectroscopy probes microstructure, dynamics and doping of metal halide perovskites75
Engineering of stimuli-responsive lipid-bilayer membranes using supramolecular systems75
Sustainable implementation of innovative technologies for water purification74
Radical generation and fate control for photocatalytic biomass conversion74
Post-synthetic modifications of metal–organic cages72
The chemistry of snake venom and its medicinal potential71
Advances in the chemistry and applications of alkali-metal–gas batteries70
Broadening the scope of biocatalytic C–C bond formation69
Chemical strategies to engineer hydrogels for cell culture68
Towards chemistry at absolute zero68
Transient directing ligands for selective metal-catalysed C–H activation67
Chemically-powered swimming and diffusion in the microscopic world61
Hole utilization in solar hydrogen production61
Solar utilization beyond photosynthesis59
Interrogating biological systems using visible-light-powered catalysis59
Control of light, spin and charge with chiral metal halide semiconductors58
Omniphobic liquid-like surfaces58
Controlling catalyst activity, chemoselectivity and stereoselectivity with the mechanical bond57
Quantifying misfolded protein oligomers as drug targets and biomarkers in Alzheimer and Parkinson diseases57
The periodic table and the physics that drives it57
Experimental characterization techniques for plasmon-assisted chemistry56
Radical-pairing-induced molecular assembly and motion55
Stereochemical expression of ns2 electron pairs in metal halide perovskites54
Exploiting non-covalent interactions in selective carbohydrate synthesis52
Carboranes in drug discovery, chemical biology and molecular imaging52
Evaluation guidelines for machine learning tools in the chemical sciences51
Stereoselectivity in Pd-catalysed cross-coupling reactions of enantioenriched nucleophiles49
Hydrogels as functional components in artificial cell systems48
Synthesis of lipid membranes for artificial cells47
DNA nanostructures as templates for biomineralization47
De novo metalloprotein design47
Chemical targets to deactivate biological and chemical toxins using surfaces and fabrics47
Advancing mechanochemical synthesis by combining milling with different energy sources46
Exploring new targets and chemical space with affinity selection-mass spectrometry45
Optimizing the semiconductor–metal-single-atom interaction for photocatalytic reactivity44
Decoupled aqueous batteries using pH-decoupling electrolytes44
DNA synthesis technologies to close the gene writing gap43
Tailoring passivators for highly efficient and stable perovskite solar cells42
The application of modern reactions in large-scale synthesis42
Direct synthesis of amorphous coordination polymers and metal–organic frameworks42
Reconfigurable microfluidics40
Silk chemistry and biomedical material designs40
Reversible catalysis40