Nature Reviews Chemistry

Article	Citations
MXene chemistry, electrochemistry and energy storage applications	612
Towards the sustainable discovery and development of new antibiotics	575
Haemostatic materials for wound healing applications	488
Late-stage C–H functionalization offers new opportunities in drug discovery	437
Recent advances in the chemistry and applications of N-heterocyclic carbenes	376
Highlights and challenges in the selective reduction of carbon dioxide to methanol	329
The concept of active site in heterogeneous catalysis	322
Circularly polarized lanthanide luminescence for advanced security inks	310
Metal–organic cages for molecular separations	303
Water at charged interfaces	251
The principles, design and applications of fused-ring electron acceptors	225
Metals to combat antimicrobial resistance	225
Advances and opportunities in the exciting world of azobenzenes	220
A unified view on catalytic conversion of biomass and waste plastics	217
Radical philicity and its role in selective organic transformations	217
Wearable chemical sensors for biomarker discovery in the omics era	215
The many flavours of mechanochemistry and its plausible conceptual underpinnings	212
A comparison of RAFT and ATRP methods for controlled radical polymerization	208
Nuclease resistance of DNA nanostructures	204
Synthesis and applications of anisotropic nanoparticles with precisely defined dimensions	200
Dual-locked spectroscopic probes for sensing and therapy	180
Graphene oxide for photonics, electronics and optoelectronics	179
Construction of C–N bonds from small-molecule precursors through heterogeneous electrocatalysis	167
Self-assembled inorganic chiral superstructures	146
Emerging chemistries and molecular designs for flow batteries	145

Chemical syntheses of bioinspired and biomimetic polymers toward biobased materials	144
Nitrene transfer catalysts for enantioselective C–N bond formation	144
Natural and synthetic carbohydrate-based vaccine adjuvants and their mechanisms of action	144
Sulfonyl fluorides as targets and substrates in the development of new synthetic methods	138
Bifunctional reagents in organic synthesis	136
Imine and imine-derived linkages in two-dimensional covalent organic frameworks	136
Chemical approaches to cryopreservation	130
Radical C(sp3)–H functionalization and cross-coupling reactions	129
Chemical strategies to engineer hydrogels for cell culture	127
Tailoring passivators for highly efficient and stable perovskite solar cells	127
Molecular excited states through a machine learning lens	126
Designing bioresponsive nanomaterials for intracellular self-assembly	125
Re-examining Fenton and Fenton-like reactions	119
A practical guide to electrosynthesis	114
Structural transformations of solid electrocatalysts and photocatalysts	113
The chemistry of snake venom and its medicinal potential	111
Radical generation and fate control for photocatalytic biomass conversion	107
Solar utilization beyond photosynthesis	106
Omniphobic liquid-like surfaces	105
Post-synthetic modifications of metal–organic cages	104
Organic reactivity from mechanism to machine learning	101
Taking phototherapeutics from concept to clinical launch	99
Silk chemistry and biomedical material designs	97
Sustainable implementation of innovative technologies for water purification	96
NMR spectroscopy probes microstructure, dynamics and doping of metal halide perovskites	94
Engineering of stimuli-responsive lipid-bilayer membranes using supramolecular systems	90
Advancing mechanochemical synthesis by combining milling with different energy sources	89
Transient directing ligands for selective metal-catalysed C–H activation	78
Towards chemistry at absolute zero	77
Hole utilization in solar hydrogen production	77
Control of light, spin and charge with chiral metal halide semiconductors	76
DNA synthesis technologies to close the gene writing gap	75
Exploiting non-covalent interactions in selective carbohydrate synthesis	73
Evaluation guidelines for machine learning tools in the chemical sciences	72
Controlling catalyst activity, chemoselectivity and stereoselectivity with the mechanical bond	72
Carboranes in drug discovery, chemical biology and molecular imaging	71
Interrogating biological systems using visible-light-powered catalysis	71
Stabilization of photoactive phases for perovskite photovoltaics	70
Chemically-powered swimming and diffusion in the microscopic world	69
Experimental characterization techniques for plasmon-assisted chemistry	69
Quantifying misfolded protein oligomers as drug targets and biomarkers in Alzheimer and Parkinson diseases	69
Decoupled aqueous batteries using pH-decoupling electrolytes	69
Optimizing the semiconductor–metal-single-atom interaction for photocatalytic reactivity	66
Radical-pairing-induced molecular assembly and motion	65
Hydrogels as functional components in artificial cell systems	65
Stereochemical expression of ns2 electron pairs in metal halide perovskites	64
Direct synthesis of amorphous coordination polymers and metal–organic frameworks	62
De novo metalloprotein design	60
Chemical targets to deactivate biological and chemical toxins using surfaces and fabrics	58
Designing electrolytes and interphases for high-energy lithium batteries	57

Synthesis of lipid membranes for artificial cells	57
DNA nanostructures as templates for biomineralization	56
Light-empowered contra-thermodynamic stereochemical editing	52
Nanoscale molecular rectifiers	51
The application of modern reactions in large-scale synthesis	51
Plasmonic phenomena in molecular junctions: principles and applications	51
Detection and analysis of chiral molecules as disease biomarkers	50
Advances in heterogeneous single-cluster catalysis	49
Extending machine learning beyond interatomic potentials for predicting molecular properties	49
Reversible catalysis	49
Energy- and atom-efficient chemical synthesis with endergonic photocatalysis	47
Reconfigurable microfluidics	46
Phosphorescence resonance energy transfer from purely organic supramolecular assembly	45
Establishing electron diffraction in chemical crystallography	44
Self-reproducing catalytic micelles as nanoscopic protocell precursors	43
Anion chemistry in energy storage devices	43
Loop dynamics and the evolution of enzyme activity	42
Natural product anticipation through synthesis	42
Non-specificity as the sticky problem in therapeutic antibody development	41
The case for data science in experimental chemistry: examples and recommendations	39
Studying protein structure and function by native separation–mass spectrometry	39
MOFs in the time domain	38
Molecular-scale mechanisms of CO2 mineralization in nanoscale interfacial water films	38
CACHE (Critical Assessment of Computational Hit-finding Experiments): A public–private partnership benchmarking initiative to enable the development of computational methods for hit-finding	37
Properties and applications of photoexcited chromophore–radical systems	36
The renaissance of chemically generated bispecific antibodies	36
Using azobenzene photocontrol to set proteins in motion	35
Time-resolved transmission electron microscopy for nanoscale chemical dynamics	35
Design principles of the use of alkynes in radical cascades	34
Synthesis and applications of mirror-image proteins	34
Rules were made to be broken	33
Recent advances in visible light-induced C(sp3)–N bond formation	33
A single-molecule blueprint for synthesis	32
Demystifying racemic natural products in the homochiral world	32
Applications of macrocycle-based solid-state host–guest chemistry	32
Near ambient N2 fixation on solid electrodes versus enzymes and homogeneous catalysts	32
Exploiting photoredox catalysis for carbohydrate modification through C–H and C–C bond activation	32
Controlling dynamics in extended molecular frameworks	31
Radical approaches to C–S bonds	31
Room-temperature phosphorescent materials derived from natural resources	31
Computational design of magnetic molecules and their environment using quantum chemistry, machine learning and multiscale simulations	30
Continuous monitoring of chemical signals in plants under stress	30
Charge frustration in ligand design and functional group transfer	28
Modern cluster design based on experiment and theory	27
Nature-inspired protein ligation and its applications	26
Ab initio quantum chemistry with neural-network wavefunctions	25
The elusive relationship between structure and colour emission in beetle luciferases	24
Halogen chemistry of solid electrolytes in all-solid-state batteries	24
Interrupted reactions in chemical synthesis	24
Induced volatolomics of pathologies	23
Prospects and challenges for nitrogen-atom transfer catalysis	22
The future of chemistry is language	22
Miniaturizing chemistry and biology using droplets in open systems	21
Strategic application of C–H oxidation in natural product total synthesis	20
Investigating the function and design of molecular materials through terahertz vibrational spectroscopy	20
Recognizing the best catalyst for a reaction	20
Ratcheting synthesis	19
Fluorinated solvents for better batteries	18
Motile behaviour of droplets in lipid systems	18
Clarifying the four core effects of high-entropy materials	17
Complementary probes for the electrochemical interface	16
Towards more sustainable curricula	15
Modern chemistry is rubbish	14
The design of PINO-like hydrogen-atom-transfer catalysts	14
Metal-catalysed C–C bond formation at cyclopropanes	14
Mechanistic interpretation of orders in catalyst greater than one	14
Small molecule approaches to targeting RNA	14
Solar reforming as an emerging technology for circular chemical industries	13
Hybrid bilayer membranes as platforms for biomimicry and catalysis	13
Targeting the human gut microbiome with small-molecule inhibitors	13
From autocatalysis to survival of the fittest in self-reproducing lipid systems	12
DNA as a universal chemical substrate for computing and data storage	12
Electrochemical hydrogenation and oxidation of organic species involving water	12
Rearrangements come to Scholl	11
Engineering chemistry to meet COP26 targets	11
Editing of polymer backbones	11
Molecular chameleons in drug discovery	11
How to drink like a liposome	11
Intercalation in 2D materials and in situ studies	11
Lipopeptides as tools in catalysis, supramolecular, materials and medicinal chemistry	10

Characterizing amorphous MOFs	10
MicroED for the study of protein–ligand interactions and the potential for drug discovery	9
Dope new organocatalysts for ATRP	9
The implication of Mycobacterium tuberculosis-mediated metabolism of targeted xenobiotics	9
An ancient battle between environment and concrete	9
Cyclopentadienyl ring activation in organometallic chemistry and catalysis	8
Perils and promise of online exams	8
Tiny but bright	8
Adapting educational experiences for the chemists of tomorrow	8
Ensemble determination by NMR data deconvolution	7
A radical departure for supramolecular chemistry	7
Hydrogen-bond filtration	7
A framework for multiexcitonic logic	7
Solvent effects in anion recognition	6
Chemical tailoring and stitching	6
Expanding the catalytic landscape of metalloenzymes with lytic polysaccharide monooxygenases	6
Aiming beyond slight increases in accuracy	6
Chemotherapy gets tuned in	6
Strategies to improve hydrogen activation on gold catalysts	6
A US perspective on closing the carbon cycle to defossilize difficult-to-electrify segments of our economy	6
From alchemist to AI chemist	6
Opportunities with calcium Grignard reagents and other heavy alkaline-earth organometallics	5
Selenium chemistry for spatio-selective peptide and protein functionalization	5
Triplet–triplet annihilation photon upconversion-mediated photochemical reactions	5
Pregnancy in the lab	5
An industrial take on developing and deploying carbon capture at scale	5
Overcoming the COF trilemma	5
Asymmetric reactions involving aryne intermediates	4
Synthetically encoded complementary oligomers	4
Engineered and total biosynthesis of fungal specialized metabolites	4
Converting benzene to pyridine	4
Packing in the proteins	4
Bifunctional beginnings	3
Boosting solid stability	3
Molecular pyramids — from tetrahedranes to [6]pyramidanes	3
An alternate route to selectivity	3
Scintillating observations	3
Halogen-powered static conversion chemistry	3
Seeking a quantum advantage with trapped-ion quantum simulations of condensed-phase chemical dynamics	3
Experiments@home	3
Mentoring is more important than ever	3
Ready and label	3
Non-symmetric stapling of native peptides	3
Threading career skills into classrooms	3
Bonds from bands	3
Unveiling the final nitrogenase	3
The need to normalize failure	3
Atroposelective catalysis	3
Copper clusters emulate the elementary	2
Cleaning up with catalysts	2
A decade of decoding	2
Gaming stereochemistry	2
Nickel doesn’t get a slice of the pi	2
Scalar coupling scales with bonding	2
Gender equity in funding	2
Forged in iron	2
A series of selective events	2
How to attract the next generation of chemists	2
Exchange made easy	2
Listening to fathers in STEM	2
Microplastics that don’t come out in the wash	2
Plastics from proteins	2
Game changer for batteries	2
Pushing the limits	2