Open Medicine

Article	Citations
Menstrual irregularities associated with COVID-19 vaccines among women in Saudi Arabia: A survey during 2022	91
The application of intravenous general anesthesia under nasopharyngeal airway assisted ventilation undergoing ureteroscopic holmium laser lithotripsy: A prospective, single-center, controlled trial	81
Amyotrophic lateral sclerosis and delayed onset muscle soreness in light of the impaired blink and stretch reflexes – watch out for Piezo2	36
Cimifugin inhibits adipogenesis and TNF-α-induced insulin resistance in 3T3-L1 cells	30
Maternal factors for neural tube defects in offspring: An umbrella review	27
Trends and future directions of autophagy in osteosarcoma: A bibliometric analysis	26
Evaluation of quality of life in patients with schizophrenia: An inpatient social welfare institution-based cross-sectional study	26
Identification and validation of autophagy-related genes in SSc	22
Antiangiogenic potential of Elaeagnus umbellata extracts and molecular docking study by targeting VEGFR-2 pathway	18
COVID-19 fear, post-traumatic stress, growth, and the role of resilience	18
Mechanism research on inhibition of gastric cancer in vitro by the extract of Pinellia ternata based on network pharmacology and cellular metabolomics	18
Temporal muscle thickness is not a prognostic predictor in patients with high-grade glioma, an experience at two centers in China	17
Retraction of “SLCO4A1-AS1 mediates pancreatic cancer development via miR-4673/KIF21B axis”	12
Mycophenolate mofetil versus cyclophosphamide plus in patients with connective tissue disease-associated interstitial lung disease: Efficacy and safety analysis	12
β2-Adrenergic receptor expression in subchondral bone of patients with varus knee osteoarthritis	11
The relationship between IFN-γ, IL-10, IL-6 cytokines, and severity of the condition with serum zinc and Fe in children infected with Mycoplasma pneumoniae	10
Vitamin C and epigenetics: A short physiological overview	10
Knockdown of CCNB1 alleviates high glucose-triggered trophoblast dysfunction during gestational diabetes via Wnt/β-catenin signaling pathway	10
lncRNA UCA1 regulates miR-132/Lrrfip1 axis to promote vascular smooth muscle cell proliferation	9
Investigating the cardioprotective potential of quercetin against tacrolimus-induced cardiotoxicity in Wistar rats: A mechanistic insights	9
ALKBH5 inhibits TNF-α-induced apoptosis of HUVECs through Bcl-2 pathway	9
Construction of a ceRNA network to reveal a vascular invasion associated prognostic model in hepatocellular carcinoma	9
KMT2A maintains stemness of gastric cancer cells through regulating Wnt/β-catenin signaling-activated transcriptional factor KLF11	8
Delivery in a vertical birth chair supported by freedom of movement during labor: A randomized control trial	8
Changes of serum CA125 and PGE2 before and after high-intensity focused ultrasound combined with GnRH-a in treatment of patients with adenomyosis	8

Huge mucinous cystic neoplasms with adhesion to the left colon: A case report and literature review	8
Serpin family A member 1 is an oncogene in glioma and its translation is enhanced by NAD(P)H quinone dehydrogenase 1 through RNA-binding activity	8
Optimizing anesthesia strategies to NSCLC patients in VATS procedures: Insights from drug requirements and patient recovery patterns	8
Endovascular thrombectomy versus intravenous thrombolysis for primary distal, medium vessel occlusion in acute ischemic stroke	8
Marital status and its correlation with age, race, and gender in prognosis of tonsil squamous cell carcinomas	8
Prevalence and antibiogram of bacteria causing urinary tract infection among patients with chronic kidney disease	8
Effectiveness of ginkgo diterpene lactone meglumine on cognitive function in patients with acute ischemic stroke	8
Clinicopathological characteristics and prognosis of young patients aged ≤45 years old with non-small cell lung cancer	8
The clinical value of the hepatic venous pressure gradient in patients undergoing hepatic resection for hepatocellular carcinoma with or without liver cirrhosis	8
Analysis of clinical characteristics in proximal and distal reflux monitoring among patients with gastroesophageal reflux disease	7
Dynamic changes in lactate-related genes in microglia and their role in immune cell interactions after ischemic stroke	7
Tollip promotes hepatocellular carcinoma progression via PI3K/AKT pathway	7
SETD1A promotes the proliferation and glycolysis of nasopharyngeal carcinoma cells by activating the PI3K/Akt pathway	7
Protective effect of ghrelin on intestinal I/R injury in rats	7
Postural stability after operative reconstruction of the AFTL in chronic ankle instability comparing three different surgical techniques	7
Toxic metals and metalloids in collagen supplements of fish and jellyfish origin: Risk assessment for daily intake	7
Epithelial-mesenchymal transition-related genes in coronary artery disease	7
Notoginsenoside R1 alleviates spinal cord injury through the miR-301a/KLF7 axis to activate Wnt/β-catenin pathway	7
circRNA_0001679/miR-338-3p/DUSP16 axis aggravates acute lung injury	7
Comparison of the ability of newly inflammatory markers to predict complicated appendicitis	6
Erratum to “Bladder-embedded ectopic intrauterine device with calculus”	6
Overexpression of miR-100-5p inhibits papillary thyroid cancer progression via targeting FZD8	6
CMSP exerts anti-tumor effects on small cell lung cancer cells by inducing mitochondrial dysfunction and ferroptosis	6
Anti-HMGCR myopathy mimicking facioscapulohumeral muscular dystrophy	6
Shikonin alleviates asthma phenotypes in mice via an airway epithelial STAT3-dependent mechanism	6
A ceRNA network mediated by LINC00475 in papillary thyroid carcinoma	6
Repeated partial splenic artery embolization for hypersplenism improves platelet count	6
A low serum uric acid concentration predicts a poor prognosis in adult patients with candidemia	6
EDNRB inhibits the growth and migration of prostate cancer cells by activating the cGMP-PKG pathway	6
AS-IV enhances the antitumor effects of propofol in NSCLC cells by inhibiting autophagy	6
ADAR1 plays a protective role in proximal tubular cells under high glucose conditions by attenuating the PI3K/AKT/mTOR signaling pathway	6
Correlation between fat-soluble vitamin levels and inflammatory factors in paediatric community-acquired pneumonia: A prospective study	6
MARK1 suppress malignant progression of hepatocellular carcinoma and improves sorafenib resistance through negatively regulating POTEE	6
Analysis of two-gene signatures and related drugs in small-cell lung cancer by bioinformatics	6
Unusual neurological manifestations of bilateral medial medullary infarction: A case report	6
lncRNA WT1-AS attenuates hypoxia/ischemia-induced neuronal injury during cerebral ischemic stroke via miR-186-5p/XIAP axis	6
Comprehensive landscape of integrator complex subunits and their association with prognosis and tumor microenvironment in gastric cancer	6
Investigating hormesis, aging, and neurodegeneration: From bench to clinics	6
Postoperative cognitive dysfunction in elderly patients with colorectal cancer: A randomized controlled study comparing goal-directed and conventional fluid therapy	6
Ureteroiliac fistula after oncological surgery: Case report and review of the literature	6
NK-cell dysfunction of acute myeloid leukemia in relation to the renin–angiotensin system and neurotransmitter genes	6
Elevated serum miR-142-5p correlates with ischemic lesions and both NSE and S100β in ischemic stroke patients	5
Role of Jumonji domain-containing protein D3 and its inhibitor GSK-J4 in Hashimoto’s thyroiditis	5
Exendin-4 regulates the MAPK and WNT signaling pathways to alleviate the osteogenic inhibition of periodontal ligament stem cells in a high glucose environment	5
Exosomal miR-93-5p regulated the progression of osteoarthritis by targeting ADAMTS9	5
Clinical efficacy of azacitidine in the treatment of middle- and high-risk myelodysplastic syndrome in middle-aged and elderly patients: A retrospective study	5
Transcription factor A, mitochondrial promotes lymph node metastasis and lymphangiogenesis in epithelial ovarian carcinoma	5
Methylation regulation for FUNDC1 stability in childhood leukemia was up-regulated and facilitates metastasis and reduces ferroptosis of leukemia through mitochondrial damage by FBXL2	5
Delayed femoral vein ligation reduces operative time and blood loss during hip disarticulation in patients with extremity tumors	5
Surgical management and outcomes of traumatic global brachial plexus injury: A concise review and our center approach	5

Outcomes and complications of hemodialysis in patients with renal cancer following bilateral nephrectomy	5
Let-7 family regulates HaCaT cell proliferation and apoptosis via the ΔNp63/PI3K/AKT pathway	5
Tetrahydropalmatine improves mitochondrial function in vascular smooth muscle cells of atherosclerosis in vitro by inhibiting Ras homolog gene family A/Rho-associated protein kinase-1 signaling	5
Mortality associated with Sjögren’s syndrome in the United States in the 1999–2020 period: A multiple cause-of-death study	5
Knockdown of NUPR1 inhibits angiogenesis in lung cancer through IRE1/XBP1 and PERK/eIF2α/ATF4 signaling pathways	5
Variations in sexual function after laparoendoscopic single-site hysterectomy in women with benign gynecologic diseases	5
Investigating the role of oviductal mucosa–endometrial co-culture in modulating factors relevant to embryo implantation	5
Immunohistochemical distribution of Bcl-2 and p53 apoptotic markers in acetamiprid-induced nephrotoxicity	5
Corrigendum to “Investigating hormesis, aging, and neurodegeneration: From bench to clinics”	5
A comparative study on the overlapping effects of clinically applicable therapeutic interventions in patients with central nervous system damage	5
Knockdown of circ_0005615 enhances the radiosensitivity of colorectal cancer by regulating the miR-665/NOTCH1 axis	5
Erratum to “lncRNA NORAD promotes lung cancer progression by competitively binding to miR-28-3p with E2F2”	5
Mechanisms of Tripterygium wilfordii Hook F on treating rheumatoid arthritis explored by network pharmacology analysis and molecular docking	5
Prognostic and diagnostic value of circulating IGFBP2 in pancreatic cancer	5
Pan-cancer and single-cell analysis of actin cytoskeleton genes related to disulfidptosis	5
Targeting PTBP1 blocks glutamine metabolism to improve the cisplatin sensitivity of hepatocarcinoma cells through modulating the mRNA stability of glutaminase	5
Evaluation of menstrual irregularities after COVID-19 vaccination: Results of the MECOVAC survey	5
Sex-specific associations of sex hormone binding globulin and risk of bladder cancer	5
Retraction of “miR-654-5p promotes gastric cancer progression via the GPRIN1/NF-κB pathway”	5
Retraction to “miR-519d downregulates LEP expression to inhibit preeclampsia development”	5
Usefulness of close surveillance for rectal cancer patients after neoadjuvant chemoradiotherapy	5
Role of ICAM-1 in triple-negative breast cancer	5
The causal relationship between immune cells and different kidney diseases: A Mendelian randomization study	5
Gene signature to predict prognostic survival of hepatocellular carcinoma	5
Clinical analysis of incomplete rupture of the uterus secondary to previous cesarean section	5
Clinical features and management of lymphoepithelial cyst	5
Clinical significance of serum MBD3 detection in girls with central precocious puberty	4
Vitamin D protects intestines from liver cirrhosis-induced inflammation and oxidative stress by inhibiting the TLR4/MyD88/NF-κB signaling pathway	4
Semaglutide treatment for type 2 diabetes in a patient with chronic myeloid leukemia: A case report and review of the literature	4
The causal effects of childhood sunburn occasions on melanoma: A univariable and multivariable Mendelian randomization study	4
The diagnostic accuracy of touch imprint cytology for sentinel lymph node metastases of breast cancer: An up-to-date meta-analysis of 4,073 patients	4
Four drug metabolism-related subgroups of pancreatic adenocarcinoma in prognosis, immune infiltration, and gene mutation	4
The effect of AQP4 on tau protein aggregation in neurodegeneration and persistent neuroinflammation after cerebral microinfarcts	4
A prospective cohort study of the impact of chronic disease on fall injuries in middle-aged and older adults	4
Ebselen: A promising therapy protecting cardiomyocytes from excess iron in iron-overloaded thalassemia patients	4
Is there any effect on imprinted genes H19, PEG3, and SNRPN during AOA?	4
Serum SIRT3 levels in epilepsy patients and its association with clinical outcomes and severity: A prospective observational study	4
Two case reports of maturity-onset diabetes of the young type 3 caused by the hepatocyte nuclear factor 1α gene mutation	4
Prognostic value of nicotinamide N-methyltransferase in human cancers: Evidence from a meta-analysis and database validation	4
Physiological and modulatory role of thioredoxins in the cellular function	4
Visfatin is negatively associated with coronary artery lesions in subjects with impaired fasting glucose	4
Identification of autophagy-related biomarkers in patients with pulmonary arterial hypertension based on bioinformatics analysis	4
Comprehensive pan-cancer investigation of carnosine dipeptidase 1 and its prospective prognostic significance in hepatocellular carcinoma	4
The function of Foxp1 represses β-adrenergic receptor transcription in the occurrence and development of bladder cancer through STAT3 activity	4
α-Hederin regulates macrophage polarization to relieve sepsis-induced lung and liver injuries in mice	4
Immune response analysis of solid organ transplantation recipients inoculated with inactivated COVID-19 vaccine: A retrospective analysis	4
Effect of gestational diabetes mellitus on lipid profile: A systematic review and meta-analysis	4
Left atrial appendage closure in conjunction with radiofrequency ablation: Effects on left atrial functioning in patients with paroxysmal atrial fibrillation	4
A prognostic signature based on seven T-cell-related cell clustering genes in bladder urothelial carcinoma	4
Radiation increases COL1A1, COL3A1, and COL1A2 expression in breast cancer	4
Silencing of long noncoding RNA MIAT inhibits the viability and proliferation of breast cancer cells by promoting miR-378a-5p expression	4
Impact of omicron wave and associated control measures in Shanghai on health management and psychosocial well-being of patients with chronic conditions	4
Pathological characteristics of liver injury induced by N,N-dimethylformamide: From humans to animal models	4
Ultrasound-guided transperineal vs transrectal prostate biopsy: A meta-analysis of diagnostic accuracy and complication rates	4
Association of polymorphisms in FBN1, MYH11, and TGF-β signaling-related genes with susceptibility of sporadic thoracic aortic aneurysm and dissection in the Zhejiang Han population	4
Exploring causal relationship between 41 inflammatory cytokines and marginal zone lymphoma: A bidirectional Mendelian randomization study	4
Bone scintigraphy and positron emission tomography in the early diagnosis of MRONJ	4
miR-29 regulates metabolism by inhibiting JNK-1 expression in non-obese patients with type 2 diabetes mellitus and NAFLD	3
Comparison of short-segment and long-segment fixation in treatment of degenerative scoliosis and analysis of factors associated with adjacent spondylolisthesis	3
METTL3-mediated methylation of CYP2C19 mRNA may aggravate clopidogrel resistance in ischemic stroke patients	3
hsa-miR-340-5p inhibits epithelial–mesenchymal transition in endometriosis by targeting MAP3K2 and inactivating MAPK/ERK signaling	3
Clinical characteristics of current COVID-19 rehabilitation outpatients in China	3
Study on the radiotherapy effect and serum neutral granulocyte lymphocyte ratio and inflammatory factor expression of nasopharyngeal carcinoma	3
Development and validation of a novel model to predict pulmonary embolism in cardiology suspected patients: A 10-year retrospective analysis	3
A cross-sectional study: Relationship between serum oxidative stress levels and arteriovenous fistula maturation in maintenance dialysis patients	3
Migraine management: Non-pharmacological points for patients and health care professionals	3
Application value of multi-parameter magnetic resonance image-transrectal ultrasound cognitive fusion in prostate biopsy	3
Examination of the causal role of immune cells in non-alcoholic fatty liver disease by a bidirectional Mendelian randomization study	3
Electromagnetic fields exposure on fetal and childhood abnormalities: Systematic review and meta-analysis	3
Identification of osteoporosis based on gene biomarkers using support vector machine	3
Lycopene ameliorates locomotor activity and urinary frequency induced by pelvic venous congestion in rats	3
Evaluation of placental oxygenation by near-infrared spectroscopy in relation to ultrasound maturation grade in physiological term pregnancies	3
Comprehensive analysis based on the disulfidptosis-related genes identifies hub genes and immune infiltration for pancreatic adenocarcinoma	3
Compilation of a self-management assessment scale for postoperative patients with aortic dissection	3
Mean corpuscular hemoglobin predicts the length of hospital stay independent of severity classification in patients with acute pancreatitis	3
CRRT influences PICCO measurements in febrile critically ill patients	3
Elevated blood acetoacetate levels reduce major adverse cardiac and cerebrovascular events risk in acute myocardial infarction	3
NORAD modulates miR-30c-5p-LDHA to protect lung endothelial cells damage	3
SELENBP1 inhibits progression of colorectal cancer by suppressing epithelial–mesenchymal transition	3
Downregulation of lncRNA XLOC_032768 in diabetic patients predicts the occurrence of diabetic nephropathy	3

SLCO4A1-AS1 mediates pancreatic cancer development via miR-4673/KIF21B axis	3
CD36-mediated podocyte lipotoxicity promotes foot process effacement	3
Atypical symptoms of malignant hyperthermia: A rare causative mutation in the RYR1 gene	3
Effect of miR-499-5p/SOX6 axis on atrial fibrosis in rats with atrial fibrillation	3
A comparative analysis of the impact of repeated administration of flavan 3-ol on brown, subcutaneous, and visceral adipose tissue	3
Population pharmacokinetics of meropenem in critically ill patients	3
Irisin-regulated lncRNAs and their potential regulatory functions in chondrogenic differentiation of human mesenchymal stem cells	3
Correlation between microvessel maturity and ISUP grades assessed using contrast-enhanced transrectal ultrasonography in prostate cancer	3
lncRNA HAGLR modulates myocardial ischemia–reperfusion injury in mice through regulating miR-133a-3p/MAPK1 axis	3
Sox9: A potential regulator of cancer stem cells in osteosarcoma	3
PVT1/miR-16/CCND1 axis regulates gastric cancer progression	3
Hydromorphone reduced the incidence of emergence agitation after adenotonsillectomy in children with obstructive sleep apnea: A randomized, double-blind study	3
Upregulated microRNA-429 confers endometrial stromal cell dysfunction by targeting HIF1AN and regulating the HIF1A/VEGF pathway	3
Expression of concern “Notoginsenoside R1 alleviates spinal cord injury through the miR-301a/KLF7 axis to activate Wnt/β-catenin pathway”	3
WDR79 promotes aerobic glycolysis of pancreatic ductal adenocarcinoma (PDAC) by the suppression of SIRT4	3
Novel lumbar plexus block versus femoral nerve block for analgesia and motor recovery after total knee arthroplasty	3
Differences in complications between hepatitis B-related cirrhosis and alcohol-related cirrhosis	3
miR-335-3p improves type II diabetes mellitus by IGF-1 regulating macrophage polarization	3
FBLIM1 mRNA is a novel prognostic biomarker and is associated with immune infiltrates in glioma	3
Association of SOX6 gene polymorphisms with Kashin-Beck disease risk in the Chinese Han population	3
Genomic analysis of immunogenic cell death-related subtypes for predicting prognosis and immunotherapy outcomes in glioblastoma multiforme	3
Adipose-derived stem cells repair radiation-induced chronic lung injury via inhibiting TGF-β1/Smad 3 signaling pathway	3
METTL16 in human diseases: What should we do next?	3
A case report of dermatomyositis with the missed diagnosis of non-small cell lung cancer and concurrence of pulmonary tuberculosis	3
MicroRNA 322-5p reduced neuronal inflammation via the TLR4/TRAF6/NF-κB axis in a rat epilepsy model	3
HPV16 E6E7 up-regulates KIF2A expression by activating JNK/c-Jun signal, is beneficial to migration and invasion of cervical cancer cells	3
TGF-β1 upregulates Sar1a expression and induces procollagen-I secretion in hypertrophic scarring fibroblasts	3
Expression levels and clinical significance of serum miR-19a/CCL20 in patients with acute cerebral infarction	3
Analysis of the clinical characteristics and prognosis of adult de novo acute myeloid leukemia (none APL) with PTPN11 mutations	3
The risk of cancer among insulin glargine users in Lithuania: A retrospective population-based study	3
The function of lncRNA EMX2OS/miR-653-5p and its regulatory mechanism in lung adenocarcinoma	3
Changes of microbiota level in urinary tract infections: A meta-analysis	3
Effect of maternal age and body mass index on induction of labor with oral misoprostol for premature rupture of membrane at term: A retrospective cross-sectional study	3
Development of a machine learning-based signature utilizing inflammatory response genes for predicting prognosis and immune microenvironment in ovarian cancer	3
Delayed graft function after renal transplantation	3
Molecular landscape of borderline ovarian tumours: A systematic review	3
Early detection of cardiovascular risk markers through non-invasive ultrasound methodologies in periodontitis patients	3
Understand how machine learning impact lung cancer research from 2010 to 2021: A bibliometric analysis	3
Correlation between the mechanism of arteriopathy in IgA nephropathy and blood stasis syndrome: A cohort study	3
Atherogenic index of plasma and coronary artery disease: A systematic review	3
Bioinformatics-based analysis of SUMOylation-related genes in hepatocellular carcinoma reveals a role of upregulated SAE1 in promoting cell proliferation	3
A 16-gene signature associated with homologous recombination deficiency for prognosis prediction in patients with triple-negative breast cancer	3
Trends in disease burden of type 2 diabetes, stroke, and hypertensive heart disease attributable to high BMI in China: 1990–2019	3
Rhein promotes skin wound healing by activating the PI3K/AKT signaling pathway	3
Malignant hyperthermia: Report on a successful rescue of a case with the highest temperature of 44.2°C	3