Open Life Sciences

Article	Citations
Combination of a bronchogenic cyst in the thoracic spinal canal with chronic myelocytic leukemia	48
Adoption value of support vector machine algorithm-based computed tomography imaging in the diagnosis of secondary pulmonary fungal infections in patients with malignant hematological disorders	27
An unusual ectopic thymoma clonal evolution analysis: A case report	22
Preparation and evaluation of LA-PEG-SPION, a targeted MRI contrast agent for liver cancer	21
PHB2 alleviates retinal pigment epithelium cell fibrosis by suppressing the AGE–RAGE pathway	20
Identification of KDM4C as a gene conferring drug resistance in multiple myeloma	20
Elevated IL-35 level and iTr35 subset increase the bacterial burden and lung lesions in Mycobacterium tuberculosis-infected mice	19
Comparison of axon extension: PTFE versus PLA formed by a 3D printer	17
Identifying two pathogenic variants in a patient with pigmented paravenous retinochoroidal atrophy	16
Comparing the differences of prokaryotic microbial community between pit walls and bottom from Chinese liquor revealed by 16S rRNA gene sequencing	16
Effectiveness of the treatment of depression associated with cancer and neuroimaging changes in depression-related brain regions in patients treated with the mediator-deuterium acupuncture method	15
Role of cerebellar cortex in associative learning and memory in guinea pigs	14
Dietary food additive monosodium glutamate with or without high-lipid diet induces spleen anomaly: A mechanistic approach on rat model	14
LL37-mtDNA regulates viability, apoptosis, inflammation, and autophagy in lipopolysaccharide-treated RLE-6TN cells by targeting Hsp90aa1	13
Low levels of sex hormone-binding globulin predict an increased breast cancer risk and its underlying molecular mechanisms	13
Bioinformatics network analyses of growth differentiation factor 11	13
Predictive analytics in smart healthcare for child mortality prediction using a machine learning approach	13
Characterization of intestinal microbiota and serum metabolites in patients with mild hepatic encephalopathy	12
Microbial diversity of milk ghee in southern Gansu and its effect on the formation of ghee flavor compounds	12
Calcifying nanoparticles initiate the calcification process of mesenchymal stem cells in vitro through the activation of the TGF-β1/Smad signaling pathway and promote the decay of echinococcosi	11
Protein Z modulates the metastasis of lung adenocarcinoma cells	11
Identification of metabolic genes for the prediction of prognosis and tumor microenvironment infiltration in early-stage non-small cell lung cancer	11
Association of ADRB2 gene polymorphisms and intestinal microbiota in Chinese Han adolescents	11
Effects of NM23 transfection of human gastric carcinoma cells in mice	10
Metastasis from small cell lung cancer to ovary: A case report	10

Isolation, identification, and drug resistance of a partially isolated bacterium from the gill of Siniperca chuatsi	10
Impact of novel herbicide based on synthetic auxins and ALS inhibitor on weed control	9
Genetic alterations of KRAS and TP53 in intrahepatic cholangiocarcinoma associated with poor prognosis	9
Small breast epithelial mucin as a useful prognostic marker for breast cancer patients	9
A case report of diagnosis and dynamic monitoring of Listeria monocytogenes meningitis with NGS	9
Development of alkaline phosphatase-scFv and its use for one-step enzyme-linked immunosorbent assay for His-tagged protein detection	9
Bioinformatics, expression analysis, and functional verification of allene oxide synthase gene HvnAOS1 and HvnAOS2 in qingke	9
Knockdown of USP7 alleviates atherosclerosis in ApoE-deficient mice by regulating EZH2 expression	8
Effect of periostin on bone metabolic and autophagy factors during tooth eruption in mice	8
Immunological responses of septic rats to combination therapy with thymosin α1 and vitamin C	8
Study on the genetic damage caused by cadmium sulfide quantum dots in human lymphocytes	8
Knockdown of DLK4 inhibits non-small cell lung cancer tumor growth by downregulating CKS2	8
ErbB4 promotes M2 activation of macrophages in idiopathic pulmonary fibrosis	8
Clusterin activates the heat shock response via the PI3K/Akt pathway to protect cardiomyocytes from high-temperature-induced apoptosis	7
Potential regulatory mechanism of TNF-α/TNFR1/ANXA1 in glioma cells and its role in glioma cell proliferation	7
Oral nifedipine and phytosterol, intravenous nicardipine, and oral nifedipine only: Three-arm, retrospective, cohort study for management of severe preeclampsia	7
Association between TGF-β1 and β-catenin expression in the vaginal wall of patients with pelvic organ prolapse	7
Hairpin in a haystack: In silico identification and characterization of plant-conserved microRNA in Rafflesiaceae	7
Hydroxysafflor yellow A improved retinopathy via Nrf2/HO-1 pathway in rats	6
Significant elevated CXCL14 and decreased IL-39 levels in patients with tuberculosis	6
Characterization and evaluation of anti-Salmonella enteritidisactivity of indigenous probiotic lactobacilli in mice	6
A biomedical decision support system for meta-analysis of bilateral upper-limb training in stroke patients with hemiplegia	6
One case of iodine-125 therapy – A new minimally invasive treatment of intrahepatic cholangiocarcinoma	6
A case of bloodstream infection caused by Neisseria gonorrhoeae	6
Interaction between the PI3K/AKT pathway and mitochondrial autophagy in macrophages and the leukocyte count in rats with LPS-induced pulmonary infection	6
Bamboo charcoal affects soil properties and bacterial community in tea plantations	6
A case of Trousseau syndrome: Screening, detection and complication	6
Effect of the genetic mutant G71R in uridine diphosphate-glucuronosyltransferase 1A1 on the conjugation of bilirubin	6
Incidence of different pressure patterns of spinal cerebellar ataxia and analysis of imaging and genetic diagnosis	6
Current research and evidence gaps on placental development in iron deficiency anemia	6
Effects of glucose and osmotic pressure on the proliferation and cell cycle of human chorionic trophoblast cells	6
Retraction to “Protocatechuic acid attenuates cerebral aneurysm formation and progression by inhibiting TNF-alpha/Nrf-2/NF-kB-mediated inflammatory mechanisms in experimental rats”	6
Effects of KCa channels on biological behavior of trophoblasts	6
Metformin mitigates osteoarthritis progression by modulating the PI3K/AKT/mTOR signaling pathway and enhancing chondrocyte autophagy	6
Long non-coding RNAs in bone formation: Key regulators and therapeutic prospects	5
Chlorate-induced molecular floral transition revealed by transcriptomes	5
Exploring the diagnostic markers of essential tremor: A study based on machine learning algorithms	5
Inflammation-related signaling pathways in tendinopathy	5
Quantitative immunohistochemistry analysis of breast Ki67 based on artificial intelligence	5
Application of the integrated airway humidification device enhances the humidification effect of the rabbit tracheotomy model	5
BTBD10 inhibits glioma tumorigenesis by downregulating cyclin D1 and p-Akt	5
Guesstimate of thymoquinone diversity in Nigella sativa L. genotypes and elite varieties collected from Indian states using HPTLC technique	5
Comprehensive phytochemical and toxicological analysis of Chenopodium ambrosioides (L.) fractions	5
Role of menopausal hormone therapy in the prevention of postmenopausal osteoporosis	5
Novel compound heterozygous mutations in TELO2 in an infant with You-Hoover-Fong syndrome: A case report and literature review	5
Case report of atypical undernutrition of hypoproteinemia type	5
Effects of maternal calcium and protein intake on the development and bone metabolism of offspring mice	5
Proteome differences of dental stem cells between permanent and deciduous teeth by data-independent acquisition proteomics	5
Phylogenetic analysis of promoter regions of human Dolichol kinase (DOLK) and orthologous genes using bioinformatics tools	5
Analysis of genetic characteristics of 436 children with dysplasia and detailed analysis of rare karyotype	5

Comparison of immunotherapy combined with stereotactic radiotherapy and targeted therapy for patients with brain metastases: A systemic review and meta-analysis	5
Differences in the flavonoid composition of the leaves, fruits, and branches of mulberry are distinguished based on a plant metabolomics approach	5
The G protein-coupled receptor-related gene signatures for predicting prognosis and immunotherapy response in bladder urothelial carcinoma	5
Case of nasopharyngeal tuberculosis complicated with cervical lymph node and pulmonary tuberculosis	4
Activation of hypermethylated P2RY1 mitigates gastric cancer by promoting apoptosis and inhibiting proliferation	4
Exploring antioxidant strategies in the pathogenesis of ALS	4
Neutrophilia with subclinical Cushing’s disease: A case report and literature review	4
Exploring the conformational dynamics and thermodynamics of EGFR S768I and G719X + S768I mutations in non-small cell lung cancer: An in silico approaches	4
15-Lipoxygenase-2 deficiency induces foam cell formation that can be restored by salidroside through the inhibition of arachidonic acid effects	4
Prostatitis as initial manifestation of Chlamydia psittaci pneumonia diagnosed by metagenome next-generation sequencing: A case report	4
Lacunar infarction aggravates the cognitive deficit in the elderly with white matter lesion	4
Downregulation of RIP3 ameliorates the left ventricular mechanics and function after myocardial infarctionviamodulating NF-κB/NLRP3 pathway	4
Evaluation of brain nerve function in ICU patients with Delirium by deep learning algorithm-based resting state MRI	4
Retraction to “A data mining technique for detecting malignant mesothelioma cancer using multiple regression analysis”	4
Association between single-nucleotide polymorphisms of NKX2.5 and congenital heart disease in Chinese population: A meta-analysis	4
Identification of iron metabolism-related genes as diagnostic signatures in sepsis by blood transcriptomic analysis	4
Influence of solvent-free extraction of fish oil from catfish (Clarias magur) heads using a Taguchi orthogonal array design: A qualitative and quantitative approach	4
Effect of berrycactus fruit (Myrtillocactus geometrizans) on glutamate, glutamine, and GABA levels in the frontal cortex of rats fed with a high-fat diet	4
The role of rapamycin in the PINK1/Parkin signaling pathway in mitophagy in podocytes	4
Fractalkine modulates pulmonary angiogenesis and tube formation by modulating CX3CR1 and growth factors in PVECs	4
Review on role of honey in disease prevention and treatment through modulation of biological activities	4
Adiponectin inhibits TGF-β1-induced skin fibroblast proliferation and phenotype transformation via the p38 MAPK signaling pathway	4
LARP1 knockdown inhibits cultured gastric carcinoma cell cycle progression and metastatic behavior	4
Long-term administration of morphine specifically alters the level of protein expression in different brain regions and affects the redox state	4
Geometric basis of action potential of skeletal muscle cells and neurons	4
Analysis of bacterial community structure of Fuzhuan tea with different processing techniques	4
Collagen changes in rabbit conjunctiva after conjunctival crosslinking	4
Macrofungal sporocarp community in the lichen Scots pine forests	4
Severe cumulative skin toxicity during toripalimab combined with vemurafenib following toripalimab alone	3
BA inhibits LPS-stimulated inflammatory response and apoptosis in human middle ear epithelial cells by regulating the Nf-Kb/Iκbα axis	3
Melatonin enhances salt tolerance in sorghum by modulating photosynthetic performance, osmoregulation, antioxidant defense, and ion homeostasis	3
Investigating the impact of wet rendering (solventless method) on PUFA-rich oil from catfish (Clarias magur) viscera	3
Novel rare genetic variants of familial and sporadic pulmonary atresia identified by whole-exome sequencing	3
Comparison of nutritional value of the wild and cultivated spiny loaches at three growth stages	3
Helicobacter pylori causes gastric dysbacteriosis in chronic gastritis patients	3
Application and teaching of computer molecular simulation embedded technology and artificial intelligence in drug research and development	3
Coexistence of hereditary spherocytosis with SPTB P.Trp1150 gene variant and Gilbert syndrome: A case report and literature review	3
Quercetin inhibits cytotoxicity of PC12 cells induced by amyloid-beta 25–35 via stimulating estrogen receptor α, activating ERK1/2, and inhibiting apoptosis	3
Value of brain injury-related indicators based on neural network in the diagnosis of neonatal hypoxic-ischemic encephalopathy	3
Knockdown of G1P3 inhibits cell proliferation and enhances the cytotoxicity of dexamethasone in acute lymphoblastic leukemia	3
Knockdown of SHMT2 enhances the sensitivity of gastric cancer cells to radiotherapy through the Wnt/β-catenin pathway	3
Biofertilizer and NPSB fertilizer application effects on nodulation and productivity of common bean (Phaseolus vulgaris L.) at Sodo Zuria, Southern Ethiopia	3
Application of metagenomic next-generation sequencing technology in the etiological diagnosis of peritoneal dialysis-associated peritonitis	3
Impact of SWCNT-conjugated senna leaf extract on breast cancer cells: A potential apoptotic therapeutic strategy	3
Non-linear associations between cardiovascular metabolic indices and metabolic-associated fatty liver disease: A cross-sectional study in the US population (2017–2020)	3
Corrigendum to “Utilization of convolutional neural networks to analyze microscopic images for high-throughput screening of mesenchymal stem cells”	3
Analysis of MDA, SOD, TAOC, MNCV, SNCV, and TSS scores in patients with diabetes peripheral neuropathy	3
β-Hydroxybutyrate upregulates FGF21 expression through inhibition of histone deacetylases in hepatocytes	3
Selection and functional identification of Dof genes expressed in response to nitrogen in Populus simonii × Populus nigra	3
IL-11 promotes Ang II-induced autophagy inhibition and mitochondrial dysfunction in atrial fibroblasts	3
Babesia microti-induced fulminant sepsis in an immunocompromised host: A case report and the case-specific literature review	3
A novel GNAS mutation in pseudohypoparathyroidism type 1a with articular flexion deformity: A case report	3
Reexamination of Aspergillus cristatus phylogeny in dark tea: Characteristics of the mitochondrial genome	3
Exopolysaccharides from Pseudomonas tolaasii inhibit the growth of Pleurotus ostreatus mycelia	3
Association between PAX9 or MSX1 gene polymorphism and tooth agenesis risk: A meta-analysis	3
ZAG promotes colorectal cancer cell proliferation and epithelial–mesenchymal transition by promoting lipid synthesis	3
Advances in diagnosis and treatment of perimenopausal syndrome	3
The altered expression of cytoskeletal and synaptic remodeling proteins during epilepsy	3
Pathogenic bacteria and treatment resistance in older cardiovascular disease patients with lung infection and risk prediction model	3
Effects of pegylated recombinant human granulocyte colony-stimulating factor on lymphocytes and white blood cells of patients with malignant tumor	3
Effect of long-term in-row branch covering on soil microorganisms in pear orchards	3
Novel risk prediction models for deep vein thrombosis after thoracotomy and thoracoscopic lung cancer resections, involving coagulation and immune function	3
Development and validation of a predictive model for immune-related genes in patients with tongue squamous cell carcinoma	3
Surgery, adjuvant immunotherapy plus chemotherapy and radiotherapy for primary malignant melanoma of the parotid gland (PGMM): A case report	3
Experimental study on the optimization of ANM33 release in foam cells	3
Isoimperatorin alleviates lipopolysaccharide-induced periodontitis by downregulating ERK1/2 and NF-κB pathways	3
Crown and diameter structure of purePinus massonianaLamb. forest in Hunan province, China	3
Studies on macrofungi diversity and discovery of new species of Abortiporus from Baotianman World Biosphere Reserve	2
Study on pecan seed germination influenced by seed endocarp	2
Transfer RNA-derived fragment tRF-36 modulates varicose vein progression via human vascular smooth muscle cell Notch signaling	2
Tanshinone IIA alleviates chondrocyte apoptosis and extracellular matrix degeneration by inhibiting ferroptosis	2
Effects of heavy metals on bacterial community surrounding Bijiashan mining area located in northwest China	2
Thymosin α1 combined with XELOX improves immune function and reduces serum tumor markers in colorectal cancer patients after radical surgery	2
Application of the FLP/LoxP-FRT recombination system to switch the eGFP expression in a model prokaryote	2
TAK-242, a toll-like receptor 4 antagonist, against brain injury by alleviates autophagy and inflammation in rats	2
Suggestions on leading an academic research laboratory group	2
Bacteriospermia – A formidable player in male subfertility	2
Erianin alleviates collagen-induced arthritis in mice by inhibiting Th17 cell differentiation	2
Enhancing faba bean (Vicia faba L.) productivity through establishing the area-specific fertilizer rate recommendation in southwest Ethiopia	2
Development of an instrument-free and low-cost ELISA dot-blot test to detect antibodies against SARS-CoV-2	2

PEI/MMNs@LNA-542 nanoparticles alleviate ICU-acquired weakness through targeted autophagy inhibition and mitochondrial protection	2
An optimization method for measuring the stomata in cassava (Manihot esculenta Crantz) under multiple abiotic stresses	2
Characteristics and karyotype analysis of a patient with turner syndrome complicated with multiple-site tumors: A case report	2
High-temperature requirement serine protease A2 inhibitor UCF-101 ameliorates damaged neurons in traumatic brain-injured rats by the AMPK/NF-κB pathway	2
Electroacupuncture on GB acupoints improves osteoporosis via the estradiol–PI3K–Akt signaling pathway	2
Exploring the coupling mode of water and fertilizer for improving growth, fruit quality, and yield of the pear in the arid region	2
Relationship between CRP gene polymorphisms and ischemic stroke risk: A systematic review and meta-analysis	2
Effects of de novo donor-specific Class I and II antibodies on graft outcomes after liver transplantation: A pilot cohort study	2
Rhodococcus equiandBrucellapulmonary mass in immunocompetent: A case report and literature review	2
Effects of the interaction of Notch and TLR4 pathways on inflammation and heart function in septic heart	2
Ten-year anemia as initial manifestation of Castleman disease in the abdominal cavity: A case report	2
My scientific genealogy and the Toronto ACDC Laboratory, 1988–2022	2
Ezrin promotes esophageal squamous cell carcinoma progression via the Hippo signaling pathway	2
The debate between electricity and heat, efficacy and safety of irreversible electroporation and radiofrequency ablation in the treatment of liver cancer: A meta-analysis	2
A comparative analysis of dendrometric, macromorphological, and micromorphological characteristics of Pistacia atlantica subsp. atlantica and Pistacia terebinthus in the middle At	2
Baculovirus-mediated endostatin and angiostatin activation of autophagy through the AMPK/AKT/mTOR pathway inhibits angiogenesis in hepatocellular carcinoma	2
Transcriptomic analysis of liver immune response in Chinese spiny frog (Quasipaa spinosa) infected with Proteus mirabilis	2
Early diagnosis for the onset of peri-implantitis based on artificial neural network	2
Research progress on fecal microbiota transplantation in tumor prevention and treatment	2
Evaluation of effects of small-incision approach treatment on proximal tibia fracture by deep learning algorithm-based magnetic resonance imaging	2
Research progress of nanoparticles in diagnosis and treatment of hepatocellular carcinoma	2
Primary retroperitoneal angiosarcoma: A case report	2
Assessment of drought tolerance indices in faba bean genotypes under different irrigation regimes	2
Multiple organ failure and death caused by Staphylococcus aureus hip infection: A case report	2
Neurodegenerative diseases and neuroinflammation-induced apoptosis	2
Evolution trend of soil fertility in tobacco-planting area of Chenzhou, Hunan Province, China	2
Comparative transcriptomes reveal molecular mechanisms of apple blossoms of different tolerance genotypes to chilling injury	2
Understory vegetation diversity patterns of Platycladus orientalis and Pinus elliottii communities in Central and Southern China	2
Effects of exogenous 2,4-epibrassinolide on photosynthetic traits of 53 cowpea varieties under NaCl stress	2
ABI3BP can inhibit the proliferation, invasion, and epithelial–mesenchymal transition of non-small-cell lung cancer cells	2
Effects of cadmium stress on fruits germination and growth of two herbage species	2
Aberrant pulmonary immune response of obese mice to periodontal infection	2
The entire chloroplast genome sequence of Asparagus cochinchinensis and genetic comparison to Asparagus species	2
Microorganism community composition analysis coupling with 15N tracer experiments reveals the nitrification rate and N2O emissions in low pH soils in Southern China	2
Continuous non-adherent culture promotes transdifferentiation of human adipose-derived stem cells into retinal lineage	2
Hepatobiliary surgery based on intelligent image segmentation technology	2
PTX3 promotes IVIG resistance-induced endothelial injury in Kawasaki disease by regulating the NF-κB pathway	2
Primary pleomorphic liposarcoma involving bilateral ovaries: Case report and literature review	2
Case report: Successful bronchoscopic interventional treatment of endobronchial leiomyomas	2
MT-12 inhibits the proliferation of bladder cells in vitro and in vivo by enhancing autophagy through mitochondrial dysfunction	2
Preliminary investigation into the genetic etiology of short stature in children through whole exon sequencing of the core family	2
The role and mechanism of esketamine in preventing and treating remifentanil-induced hyperalgesia based on the NMDA receptor–CaMKII pathway	2
NAT10 promotes radiotherapy resistance in non-small cell lung cancer by regulating KPNB1-mediated PD-L1 nuclear translocation	2
Computational analysis of polymorphic residues in maltose and maltotriose transporters of a wild Saccharomyces cerevisiae strain	2
Role of circRMRP and circRPL27 in chronic obstructive pulmonary disease	2
IgG4-related disease complicated by PLA2R-associated membranous nephropathy: A case report	2
Genome-wide identification of MAPK family genes and their response to abiotic stresses in tea plant (Camellia sinensis)	2
Silencing circular RNA-friend leukemia virus integration 1 restrained malignancy of CC cells and oxaliplatin resistance by disturbing dyskeratosis congenita 1	2
Research progress on gas signal molecular therapy for Parkinson’s disease	2
Investigation of genotype diversity of 7,804 norovirus sequences in humans and animals of China	2
Active legumain promotes invasion and migration of neuroblastoma by regulating epithelial-mesenchymal transition	2
Down-regulation of COL1A1 inhibits tumor-associated fibroblast activation and mediates matrix remodeling in the tumor microenvironment of breast cancer	2
The complete chloroplast genome of Gerbera piloselloides (L.) Cass., 1820 (Carduoideae, Asteraceae) and its phylogenetic analysis	2
A review of the current state of the computer-aided diagnosis (CAD) systems for breast cancer diagnosis	2
Decreased serum TIMP4 levels in patients with rheumatoid arthritis	2