JCI Insight

Article	Citations
Slick K+ channels contribute to cardiac remodeling, fibrosis and dysfunction in post-infarction hearts	213
Ataxia and cerebellar hypoexcitability in a mouse model of SCN1B-linked Dravet syndrome	196
A double-edged sword: iron regulation in alveolar lung epithelial repair	133
A hypomorphic Mpi mutation unlocks an in vivo tool for studying global N-glycosylation deficiency	129
Allelic heterogeneity of TTNtv dilated cardiomyopathy can be modeled in adult zebrafish	127
Mutation in IR or IGF1R produces features of long-lived mice while maintaining metabolic health	106
Intranodal expansion of follicular T helper cells in patients with multiple sclerosis	101
Macrophage ferritin heavy chain/α-synuclein regulatory axis modulates ferroptosis during kidney injury	99
Somatic mutations reveal hyperactive Notch signaling in prurigo nodularis	95
Health outcomes after national acute sleep deprivation events among the American public	90
Inhibition of the angiotensin-converting enzyme N-terminal catalytic domain prevents endogenous opioid degradation in brain tissue	86
Type I interferons and TGF-β cooperate to induce liver fibrosis during HIV-1 infection under antiretroviral therapy	82
Assemblies of JAG1 and JAG2 determine tracheobronchial cell fate in mucosecretory lung disease	82
UBE3A expression during early postnatal brain development is required for proper dorsomedial striatal maturation	79
Calcineurin inhibitors stimulate Kir4.1/Kir5.1 of the distal convoluted tubule to increase NaCl cotransporter	78
TIAM1 acts as an actin organization regulator to control adipose tissue–derived pericyte cell fate	73
Interferon-dependent signaling is critical for viral clearance in airway neutrophils	72
Endothelial-derived FABP4 constitutes the majority of basal circulating hormone and regulates lipolysis-driven insulin secretion	72
Key patient demographics shape innate immune topography in noncritical hypoxic COVID-19 pneumonia	71
Structural and functional analyses of a germline KRAS T50I mutation provide insights into Raf activation	71
A dominant pathogenic MEFV mutation causes atypical pyrin-associated periodic syndromes	69
Glucose-dependent insulinotropic polypeptide receptor signaling alleviates gut inflammation in mice	67
LMAN1 serves as a cargo receptor for thrombopoietin	66
Constitutive deletion of the obscurin-Ig58/59 domains induces atrial remodeling and Ca2+-based arrhythmogenesis	64
Bariatric surgery improves postprandial VLDL kinetics and restores insulin-mediated regulation of hepatic VLDL production	63

Endothelial deletion of adipose triglyceride lipase protects against heart failure with preserved ejection fraction	63
Autosomal-dominant macular dystrophy linked to a chromosome 17 tandem duplication	63
Lack of SPNS1 results in accumulation of lysolipids and lysosomal storage disease in mouse models	63
Multicomponent parenteral lipid emulsions do not prevent liver injury in neonatal pigs with obstructive cholestasis	62
Urine proteomic signatures of kidney function decline after hospitalization	62
Regulation of selective class switching provides long-term therapeutic benefits for hay fever	62
The CLCA1/TMEM16A/Cl– current axis associates with H2S deficiency in diabetic kidney injury	61
Sclerostin blockade inhibits bone resorption through PDGF receptor signaling in osteoblast lineage cells	61
Dysregulated immunologic landscape of the early host response in melioidosis	61
Lipidomics of infant mesenchymal stem cells associate with the maternal milieu and child adiposity	59
Immunotoxin-mediated depletion of Gag-specific CD8+ T cells undermines natural control of SIV	59
Pregnancy dedifferentiates memory CD8+ T cells into hypofunctional cells with exhaustion-enriched programs	59
Irx1 mechanisms for oral epithelial basal stem cell plasticity during reepithelialization after injury	59
Human IL-6 fosters long-term engraftment of patient-derived disease-driving myeloma cells in immunodeficient mice	58
Mineralocorticoid receptor antagonists and glucocorticoids differentially affect skeletal muscle inflammation and pathology in muscular dystrophy	58
BPDCN MYB fusions regulate cell cycle genes, impair differentiation, and induce myeloid–dendritic cell leukemia	58
Chemotherapy-induced reactive myelopoiesis promotes expansion of immunosuppressive neutrophil-like monocytes in mice and humans	58
Characterization of anticancer therapy–induced microvascular dysfunction in patients with breast cancer supports targeted intervention	57
Programmed cycle-induced endometrial perturbations do not independently influence angiogenic imbalance or hypertensive disorders in pregnancy	55
Dipeptidase-1–knockout mice develop invasive tumors with features of microsatellite-unstable colorectal cancer	55
Fatal COVID-19 outcomes are associated with an antibody response targeting epitopes shared with endemic coronaviruses	55
Development of a humanized mouse model with functional human materno-fetal interface immunity	55
T cell metabolic reprogramming in acute kidney injury and protection by glutamine blockade	55
De novo variant in RING finger protein 213 causes systemic vasculopathy	55
Endothelial cell glycogen synthase kinase 3β promotes lipotoxic endotheliopathy and liver inflammation in MASH	54
AXL inhibition suppresses early allograft monocyte-to-macrophage differentiation and prolongs allograft survival	54
CNS-dominant human FMRP isoform rescues seizures, fear, and sleep abnormalities in Fmr1-KO mice	54
Dynamic remodeling of portal vessels by Clec4g+ endothelial cells in liver growth and homeostasis	54
Allergen induces pulmonary neuroendocrine cell hyperplasia in a model of asthma	54
CD4+ and CD8+ T cells are not the main driver of Lassa fever pathogenesis in macaques	54
Pharmacological induction of MHC-I expression in tumor cells revitalizes T cell antitumor immunity	54
CD11c+ myeloid cell exosomes reduce intestinal inflammation during colitis	53
From improvised to intentional: re-imagining the physician-scientist career path	53
Hypoxia-activated prodrug and antiangiogenic therapies cooperatively treat pancreatic cancer but elicit immunosuppressive G-MDSC infiltration	52
Benchmarking urinary cell transcriptomes for noninvasive differentiation of BK polyomavirus–associated nephropathy from T cell–mediated rejection	52
Lymphatic disorders caused by mosaic, activating KRAS variants respond to MEK inhibition	52
Longitudinal lipidomic profiles of left ventricular mass and left ventricular hypertrophy in American Indians	51
Th2 skewing in patients with disseminated coccidioidomycosis	51
Effects of SIPA1L1 on trabecular meshwork extracellular matrix protein accumulation and cellular phagocytosis in POAG	51
Intimomedial tears of the aorta heal by smooth muscle cell–mediated fibrosis without atherosclerosis	50
Lipidomic profiling of human adiposomes identifies specific lipid shifts linked to obesity and cardiometabolic risk	50
Caspase-4/11 promotes hyperlipidemia and chronic kidney disease–accelerated vascular inflammation by enhancing trained immunity	49
Cleavage of N-terminus of polycystin-1 increases calcium permeability of polycystin-1/2 receptor channel complexes	49
Single-cell landscape analysis unravels molecular programming of the human B cell compartment in chronic GVHD	48
Regulation of human and mouse bystander T cell activation responses by PD-1	48
Pericentrin deficiency in smooth muscle cells augments atherosclerosis through HSF1-driven cholesterol biosynthesis and PERK activation	48
Single nuclei RNA-sequencing reveals transcriptional heterogeneity in the blastema of favorable histology Wilms tumor	48
Profound reduction of HIV-1 reservoir cells over 3 decades of antiretroviral therapy started in early infancy	47
NSD1-916aa encoded by CircNSD1 contributes to AKI-to-CKD transition through inducing ferroptosis in tubular epithelial cells	47
Angiopoietin-like 3 monomers are abundant in human plasma but are unable to inhibit endothelial lipase	46

Enhancing DC cancer vaccine by allogeneic MHC class II expression and Treg depletion	46
A versatile laser-induced porcine model of outer retinal and choroidal degeneration for preclinical testing	46
IL-21 enhances the cytotoxicity of intratumoral CD8+ T cells, improving radiation efficacy	46
Elevated apolipoprotein C3 augments diabetic kidney disease and associated atherosclerosis in type 2 diabetes	46
Tubulin tyrosine ligase variant perturbs microtubule tyrosination, causing hypertrophy in patient-specific and CRISPR gene-edited iPSC-cardiomyocytes	46
Site-1 protease–mediated cholesterol metabolism is essential for lymphatic development in mice	45
Differential histone acetylation and super-enhancer regulation underlie melanoma cell dedifferentiation	45
Protein kinase G2 activation restores Wnt signaling and bone mass in glucocorticoid-induced osteoporosis in mice	45
Outpatient COVID-19 convalescent plasma recipient antibody thresholds correlated to reduced hospitalizations within a randomized trial	45
Rapamycin immunomodulation utilizes time-dependent alterations of lymph node architecture, leukocyte trafficking, and gut microbiome	44
mTOR inhibition overcomes RSK3-mediated resistance to BET inhibitors in small cell lung cancer	44
Intragraft memory-like CD127hiCD4+Foxp3+ Tregs maintain transplant tolerance	44
Sorting nexin 10 sustains PDGF receptor signaling in glioblastoma stem cells via endosomal protein sorting	44
First-in-class multifunctional TYMS nonclassical antifolate inhibitor with potent in vivo activity that prolongs survival	43
Mutational landscape of atherosclerotic plaques reveals large clonal cell populations	43
Multiantigen pan-sarbecovirus DNA vaccines generate protective T cell immune responses	43
CAVIN3 deficiency promotes vascular normalization in ocular neovascular disease via ERK/JAG1 signaling pathway	43
Anti-CELA1 antibody KF4 prevents emphysema by inhibiting stretch-mediated remodeling	43
Potentiation of fentanyl-induced respiratory depression by alcohol is not fully reversed by naloxone	42
Splicing variants in MYRF cause partial loss of function in the retinal pigment epithelium leading to nanophthalmos	42
Lipid-nanoparticle-mediated base editing of the trabecular meshwork rescues glaucoma in vivo	42
Allele-specific silencing of the gain-of-function mutation in Huntington’s disease using CRISPR/Cas9	41
Spatial transcriptomics reveals immune-stromal crosstalk within the synovium of patients with juvenile idiopathic arthritis	41
UHRF1 deficiency exacerbates intestinal inflammation by epigenetic modulation of NPY1R gene methylation	41
Filaggrin loss-of-function variants are associated with atopic dermatitis phenotypes in a diverse, early-life prospective cohort	41
Hepatic FASN deficiency differentially affects nonalcoholic fatty liver disease and diabetes in mouse obesity models	41
Long noncoding RNA GAS5 disrupts intestinal epithelial barrier function by increasing small vault RNA levels	41
Dual-degree pathways in the residency match: a comparative analysis of application behaviors and outcomes	41
Hypothalamic insulin resistance in type 2 diabetes is localized to the posterior hypothalamus	41
Loss of fungal sensing exacerbates liver injury in a murine model of MASLD	41
Transcriptional signature of induced neurons differentiates virologically suppressed people with HIV from people without HIV	41
Immunological landscape of human lymphoid explants during measles virus infection	40
IL-15 reprogramming compensates for NK cell mitochondrial dysfunction in HIV-1 infection	40
Mitochondrial and NAD+ metabolism predict recovery from acute kidney injury in a diverse mouse population	40
FGF receptors mediate cellular senescence in the cystic fibrosis airway epithelium	40
Prenatal alcohol exposure is associated with altered feto-placental blood flow and sex-specific placental changes	40
Focusing HIV-1 Gag T cell responses to highly conserved regions by DNA vaccination in HVTN 119	40
Histone demethylase JARID1C/KDM5C regulates Th17 cells by increasing IL-6 expression in diabetic plasmacytoid dendritic cells	40
Longitudinal trajectories of branched chain amino acids through young adulthood and diabetes in later life	40
Responders to low-dose ATG induce CD4+ T cell exhaustion in type 1 diabetes	39
A heterozygous LAMA5 variant may contribute to slowly progressive, vinculin-enhanced familial FSGS and pulmonary defects	39
SPOP mutations increase PARP inhibitor sensitivity via CK2/PIAS1/SPOP axis in prostate cancer	39
Evidence of a Sjögren’s disease–like phenotype following COVID-19 in mice and humans	39
ST6GAL1 sialyltransferase promotes acinar to ductal metaplasia and pancreatic cancer progression	38
IL-13 and calpain-14 suppress the expression of SPINK7 by regulating OVOL1 in eosinophilic esophagitis	38
Longitudinal associations of insulin resistance with change in bone mineral density in midlife women	38
Horizontal transmission of gut microbiota attenuates mortality in lung fibrosis	38
Mitochondria-sequestered Aβ renders synaptic mitochondria vulnerable in the elderly with a risk of Alzheimer disease	38
hsa-miR-548v controls the viscoelastic properties of human cardiomyocytes and improves their relaxation rates	38
HIF1A-dependent induction of alveolar epithelial PFKFB3 dampens acute lung injury	38
HIV-1–infected T cell clones are shared across cerebrospinal fluid and blood during ART	38
Autogenic-regenerated intestinal transplantation improves outcomes in short bowel syndrome	38
Thyroidal expression of ER molecular chaperone GRP170 is required for efficient TSH-mediated thyroid hormone synthesis	38
Cord blood proteomics identifies biomarkers of early-onset neonatal sepsis	37
Hedgehog activation promotes osteogenic fates of growth plate resting zone chondrocytes through transient clonal competency	37
Anoctamin-5 deficiency enhances ATG9A-dependent autophagy, inducing osteogenesis and gnathodiaphyseal dysplasia–like bone formation	37
Hypercapnia alters stroma-derived Wnt production to limit β-catenin signaling and proliferation in AT2 cells	37
S-nitrosylation attenuates pregnane X receptor hyperactivity and acetaminophen-induced liver injury	37
Nrf2 activator peptide protects the brain from cerebral vascular dysfunction in alcohol ingestion	37
The gut microbiome enhances breast cancer immunotherapy following bariatric surgery	37
Negative regulation of human IL-33 in endothelium during allergic airway inflammation	37
An immunosuppressed microenvironment distinguishes lateral ventricle–contacting glioblastomas	37
Age-related differences in immune responses to inactivated influenza and adjuvanted recombinant herpes zoster vaccines	37
Ebola virus protein VP40 stimulates IL-12– and IL-18–dependent activation of human natural killer cells	37
Intergenic sequences harboring potential enhancer elements contribute to Axenfeld-Rieger syndrome by regulating PITX2	37
Uric acid formation is driven by crosstalk between skeletal muscle and other cell types	37
Single-nucleus RNA-Seq reveals singular gene signatures of human ductal cells during adaptation to insulin resistance	37
Association of oxidized ApoB and oxidized ApoA-I with high-risk coronary plaque features in cardiovascular disease	36
Human immune phenotyping reveals accelerated aging in type 1 diabetes	36
The EMT factor ZEB1 paradoxically inhibits EMT in BRAF-mutant carcinomas	36
Circulating extracellular vesicles in human cardiorenal syndrome promote renal injury in a kidney-on-chip system	36
SARA suppresses myofibroblast precursor transdifferentiation in fibrogenesis in a mouse model of scleroderma	36
Isolevuglandins disrupt PU.1-mediated C1q expression and promote autoimmunity and hypertension in systemic lupus erythematosus	35
Modeling skeletal dysplasia in Hurler syndrome using patient-derived bone marrow osteoprogenitor cells	35
Preservation of naive-phenotype CD4+ T cells after vaccination contributes to durable immunity	35
Keratinocyte-derived cytokine TSLP promotes growth and metastasis of melanoma by regulating the tumor-associated immune microenvironment	35
Evaluating precision medicine approaches for gene therapy in patient-specific cellular models of Bietti crystalline dystrophy	35
Dichloroacetate improves mitochondrial function, physiology, and morphology in FBXL4 disease models	35
Catalytic isoforms of AMP-activated protein kinase differentially regulate IMPDH activity and photoreceptor neuron function	35
In vivo AAV9-Myo7a gene rescue restores hearing and cholinergic efferent innervation in inner hair cells	35

Evofosfamide for the treatment of human papillomavirus-negative head and neck squamous cell carcinoma	34
DAB2IP loss in luminal a breast cancer leads to NF-κB–associated aggressive oncogenic phenotypes	34
β-Catenin disruption decreases macrophage exosomal α-SNAP and impedes Treg differentiation in acute liver injury	34
Rapid systemic spread and minimal immune responses following SIVsab intrarectal transmission in African green monkeys	34
Improved mitochondrial function in the hearts of sarcolipin-deficient dystrophin and utrophin double-knockout mice	34
Mechanisms underlying age-associated exacerbation of pulmonary veno-occlusive disease	34
Transcriptome and microbiome-immune changes across preinvasive and invasive anal cancer lesions	34
Expansion of the HSV-2–specific T cell repertoire in skin after immunotherapeutic HSV-2 vaccine	34
Effects of FGF21, soluble TGFBR2, and environmental temperature on metabolic dysfunction in lipodystrophic mice	33
A role for the transcriptional coregulator RIP140 in the control of muscle endurance fitness	33
LYVE1 ectodomain shedding blunts lymphatic transmigration and clearance of macrophages during kidney injury	33
Preclinical assessment of oral TLR7 agonist SA-5 in a nonhuman primate model	33
Myocardial lipin1 protects the heart against ischemic injury by preserving lipid homeostasis	33
Cardiac conduction system malformations in heterotaxy result from dysregulated Pitx2 expression	33
Deletion of Ptpn2 in B cells promotes autoimmunity via TLR and JAK/STAT signaling	33
The aberrant tonsillar microbiota modulates autoimmune responses in rheumatoid arthritis	33
H1N1 challenge results in rapid recall of stem-specific immunity in HA stem nanoparticle–vaccinated newborn monkeys	33
PTP1B inhibitors protect against acute lung injury and regulate CXCR4 signaling in neutrophils	32
CD34hi subset of synovial fibroblasts contributes to fibrotic phenotype of human knee osteoarthritis	32
β Cell mass expansion during puberty involves serotonin signaling and determines glucose homeostasis in adulthood	32
Early-life viral infection generates pathological tissue-resident memory cells that contribute to asthma-like disease	32
Chronic pharmacologic manipulation of dopamine transmission ameliorates metabolic disturbance in Trappc9-linked brain developmental syndrome	32
Oxygen-carrying nanoemulsions and respiratory hyperoxia eliminate tumor hypoxia–induced immunosuppression	32
Ancestry-based differences in the immune phenotype are associated with lupus activity	32
Restoring calcium homeostasis in Purkinje cells arrests neurodegeneration and neuroinflammation in the ARSACS mouse model	32
CCL3 in the bone marrow microenvironment causes bone loss and bone marrow adiposity in aged mice	31
KLF4 is a therapeutically tractable brake on fibroblast activation that promotes resolution of pulmonary fibrosis	31
IFN-λ uniquely promotes CD8 T cell immunity against SARS-CoV-2 relative to type I IFN	31
Temporal development of T cell receptor repertoires during childhood in health and disease	31
HIV viral transcription and immune perturbations in the CNS of people with HIV despite ART	31
Lack of myotubularin phosphatase activity is the main cause of X-linked myotubular myopathy	31
Epithelial Gab1 calibrates RIPK3-dependent necroptosis to prevent intestinal inflammation	31
A phase I study of autologous mesenchymal stromal cells for severe steroid-dependent nephrotic syndrome	31
Inflammation-induced TRIM21 represses hepatic steatosis by promoting the ubiquitination of lipogenic regulators	31
Spatiotemporal mapping of immune and stem cell dysregulation after volumetric muscle loss	31
Endothelial response to blood-brain barrier disruption in the human brain	31
Hepatocyte hedgehog signaling controls ferroptosis to alleviate aging-related organ dysfunction	31
MYO1C is a urinary extracellular vesicle biomarker and mediator of podocyte injury in diabetic nephropathy	31
Perivascular inflammation in the progression of aortic aneurysms in Marfan syndrome	31
Persistent hepatic IFN system activation in HBV-HDV infection determines viral replication dynamics and therapeutic response	30
ADAM17-mediated EGFR ligand shedding directs macrophage-promoted cancer cell invasion	30
Detection of cytokine release syndrome using wearables and cytokine profiling following CAR-T therapy for myeloma	30
Identification and validation of a T cell receptor targeting KRAS G12V in HLA-A*11:01 pancreatic cancer patients	30
Functional Pdgfra fibroblast heterogeneity in normal and fibrotic mouse lung	30
SARS-CoV-2 infection of sustentacular cells disrupts olfactory signaling pathways	30
SLC6A19 inhibition facilitates urinary neutral amino acid excretion and lowers plasma phenylalanine	30
LIN28B promotes cell invasion and colorectal cancer metastasis via CLDN1 and NOTCH3	30
Notch-mediated hepatocyte MCP-1 secretion causes liver fibrosis	30
suPAR links a dysregulated immune response to tissue inflammation and sepsis-induced acute kidney injury	30
Orai1 calcium channel inhibition prevents progression of chronic pancreatitis	29
ABT1 modifies SMARD1 pathology via interactions with IGHMBP2 and stimulation of ATPase and helicase activity	29
ERK hyperactivation in epidermal keratinocytes impairs intercellular adhesion and drives Grover disease pathology	29
Cross-species single-cell analysis uncovers the immunopathological mechanisms associated with IgA nephropathy progression	29
Mapping the plasma proteomic architecture of systemic lupus erythematosus	29
Plasma cells in human pancreatic ductal adenocarcinoma secrete antibodies against self-antigens	29
Consecutive BNT162b2 mRNA vaccination induces short-term epigenetic memory in innate immune cells	29
Piperlongumine overcomes osimertinib resistance via governing ubiquitination-modulated Sp1 turnover	29
Involvement of impaired carnitine-induced fatty acid oxidation in experimental and human diabetic kidney disease	29
HSPA12A maintains aerobic glycolytic homeostasis and Histone3 lactylation in cardiomyocytes to attenuate myocardial ischemia/reperfusion injury	29
A therapeutic HBV vaccine containing a checkpoint modifier enhances CD8+ T cell and antiviral responses	28
Radiotherapy exposure directly damages the uterus and causes pregnancy loss	28
Immunosurveillance shapes the emergence of neo-epitope landscapes of sarcomas, revealing prime targets for immunotherapy	28
AI-assisted discovery of an ethnicity-influenced driver of cell transformation in esophageal and gastroesophageal junction adenocarcinomas	28
ISG15/GRAIL1/CD3 axis influences survival of patients with esophageal adenocarcinoma	28
SNRNP70 regulates the splicing of CD55 to promote osteosarcoma progression	28
The ACTH test fails to diagnose adrenal insufficiency and augments cytokine production in sepsis	28
Intraperitoneal injection of class A TLR9 agonist enhances anti–PD-1 immunotherapy in colorectal peritoneal metastases	28
Osteopontin promotes age-related adipose tissue remodeling through senescence-associated macrophage dysfunction	28
New Pseudomonas infections drive Pf phage transmission in CF airways	28
A miRNA/CXCR4 signaling axis impairs monopoiesis and angiogenesis in diabetic critical limb ischemia	28
Parathyroid hormone 1 receptor signaling mediates breast cancer metastasis to bone in mice	28
Go, Flight	28
Characterization of vascular tortuosity throughout the murine oxygen-induced retinopathy model of ischemic retinopathy	28
Pharmacological PIK3C2B inhibition rescues XLMTM phenotype in mouse models and identifies molecular markers of disease	28
Mitochondrial β-oxidation of adipose-derived fatty acids by osteoblasts fuels parathyroid hormone–induced bone formation	28
Subtype C HIV-1 reservoirs throughout the body in ART-suppressed individuals	28
iGATE analysis improves the interpretability of single-cell immune landscape of influenza infection	28
Granzyme B cleaves tenascin-C to release its C-terminal domain in rheumatoid arthritis	28
Histamine-induced RPS6 phosphorylation in dendritic cells is associated with the severity of peanut allergic reactions	27
The administration of exogenous HSP47 as a collagen-specific therapeutic approach	27
AFF3 maintains metabolic quiescence in naïve CD8 T cells and prevents premature immune aging	27
Label-free single-cell phenotyping to determine tumor cell heterogeneity in pancreatic cancer in real time	27
The native human glomerulus features a slit diaphragm resembling a densely interwoven fishnet	27
Insights and modulation of RNA polymerase–dependent R-loop and dsRNA in Fanconi anemia hematopoietic stem cells	27
Progressive HNF1A-MODY pathophysiology revealed by a translational mouse model	27
Antibody-oligonucleotide conjugate achieves CNS delivery in animal models for spinal muscular atrophy	27
Combined molnupiravir-nirmatrelvir treatment improves the inhibitory effect on SARS-CoV-2 in macaques	27
Atrial fibrillation–induced neurocognitive and vascular dysfunction is averted by mitochondrial oxidative stress reduction	27
Differential effects of HDAC8 targeting on Foxp3+ Tregs and effector T cells promote antitumor immunity	27
FAP PET identifies earlycardiac molecular changesinduced by doxorubicin chemotherapy	27
NEXN regulates vascular smooth muscle cell phenotypic switching and neointimal hyperplasia	27
Macrophages orchestrate antiviral defense and epithelial repair in a human iPSC-derived alveolar air-liquid interface	27
Rheumatoid arthritis synovial fluid induces JAK-dependent intracellular activation of human sensory neurons	26
De novo VPS16 missense variant causes infantile-onset dystonia with defective autophagic flux	26
Role of cGAS/STING pathway in aging and sexual dimorphism in diabetic kidney disease	26