JCI Insight

Article	Citations
A hypomorphic Mpi mutation unlocks an in vivo tool for studying global N-glycosylation deficiency	162
Immunotoxin-mediated depletion of Gag-specific CD8+ T cells undermines natural control of SIV	152
Recurrent moderate hypoglycemia accelerates the progression of Alzheimer’s disease through impairment of the TRPC6/GLUT3 pathway	146
Intranodal expansion of follicular T helper cells in patients with multiple sclerosis	118
Fibrotic lung disease inhibits immune responses to staphylococcal pneumonia via impaired neutrophil and macrophage function	111
Lack of SPNS1 results in accumulation of lysolipids and lysosomal storage disease in mouse models	111
Allelic heterogeneity of TTNtv dilated cardiomyopathy can be modeled in adult zebrafish	108
AXL inhibition suppresses early allograft monocyte-to-macrophage differentiation and prolongs allograft survival	102
Multicomponent parenteral lipid emulsions do not prevent liver injury in neonatal pigs with obstructive cholestasis	100
Bariatric surgery improves postprandial VLDL kinetics and restores insulin-mediated regulation of hepatic VLDL production	88
TIAM1 acts as an actin organization regulator to control adipose tissue–derived pericyte cell fate	84
Irx1 mechanisms for oral epithelial basal stem cell plasticity during reepithelialization after injury	83
Dipeptidase-1–knockout mice develop invasive tumors with features of microsatellite-unstable colorectal cancer	82
Endothelial deletion of adipose triglyceride lipase protects against heart failure with preserved ejection fraction	81
De novo variant in RING finger protein 213 causes systemic vasculopathy	79
The CLCA1/TMEM16A/Cl– current axis associates with H2S deficiency in diabetic kidney injury	76
Autosomal-dominant macular dystrophy linked to a chromosome 17 tandem duplication	73
Effects of SIPA1L1 on trabecular meshwork extracellular matrix protein accumulation and cellular phagocytosis in POAG	73
Longitudinal lipidomic profiles of left ventricular mass and left ventricular hypertrophy in American Indians	73
Constitutive deletion of the obscurin-Ig58/59 domains induces atrial remodeling and Ca2+-based arrhythmogenesis	72
Epac1–/– and Epac2–/– mice exhibit deficient epithelial Na+ channel regulation and impaired urinary Na+ conservation	72
Lipidomics of infant mesenchymal stem cells associate with the maternal milieu and child adiposity	70
Interferon-dependent signaling is critical for viral clearance in airway neutrophils	70
Steroid-sensitive nephrotic syndrome candidate gene CLVS1 regulates podocyte oxidative stress and endocytosis	69
T cell metabolic reprogramming in acute kidney injury and protection by glutamine blockade	69

Durability of ChAdOx1 nCoV-19 vaccination in people living with HIV	69
Allergen induces pulmonary neuroendocrine cell hyperplasia in a model of asthma	67
Hypoxia-activated prodrug and antiangiogenic therapies cooperatively treat pancreatic cancer but elicit immunosuppressive G-MDSC infiltration	66
EBAG9 controls CD8+ T cell memory formation responding to tumor challenge in mice	65
Key patient demographics shape innate immune topography in noncritical hypoxic COVID-19 pneumonia	61
Exploiting 4-1BB immune checkpoint to enhance the efficacy of oncolytic virotherapy for diffuse intrinsic pontine gliomas	61
Type I interferons and TGF-β cooperate to induce liver fibrosis during HIV-1 infection under antiretroviral therapy	61
LMAN1 serves as a cargo receptor for thrombopoietin	61
Pregnancy dedifferentiates memory CD8+ T cells into hypofunctional cells with exhaustion-enriched programs	60
Fatal COVID-19 outcomes are associated with an antibody response targeting epitopes shared with endemic coronaviruses	60
Lymph node CXCR5+ NK cells associate with control of chronic SHIV infection	60
Myocardial ATP depletion detected noninvasively predicts sudden cardiac death risk in patients with heart failure	60
Sclerostin blockade inhibits bone resorption through PDGF receptor signaling in osteoblast lineage cells	60
CD4+ and CD8+ T cells are not the main driver of Lassa fever pathogenesis in macaques	58
Calcineurin inhibitors stimulate Kir4.1/Kir5.1 of the distal convoluted tubule to increase NaCl cotransporter	58
CNS-dominant human FMRP isoform rescues seizures, fear, and sleep abnormalities in Fmr1-KO mice	56
UBE3A expression during early postnatal brain development is required for proper dorsomedial striatal maturation	56
BPDCN MYB fusions regulate cell cycle genes, impair differentiation, and induce myeloid–dendritic cell leukemia	55
11C-Para-aminobenzoic acid PET imaging of S. aureus and MRSA infection in preclinical models and humans	54
Coimmunomodulation of tumor and tumor-draining lymph nodes during in situ vaccination promotes antitumor immunity	54
Structural and functional analyses of a germline KRAS T50I mutation provide insights into Raf activation	53
Regulation of selective class switching provides long-term therapeutic benefits for hay fever	53
Ataxia and cerebellar hypoexcitability in a mouse model of SCN1B-linked Dravet syndrome	53
Pharmacological induction of MHC-I expression in tumor cells revitalizes T cell antitumor immunity	53
Urine proteomic signatures of kidney function decline after hospitalization	53
Health outcomes after national acute sleep deprivation events among the American public	52
Glucose-dependent insulinotropic polypeptide receptor signaling alleviates gut inflammation in mice	51
Characterization of anticancer therapy–induced microvascular dysfunction in patients with breast cancer supports targeted intervention	51
Assemblies of JAG1 and JAG2 determine tracheobronchial cell fate in mucosecretory lung disease	51
Mineralocorticoid receptor antagonists and glucocorticoids differentially affect skeletal muscle inflammation and pathology in muscular dystrophy	51
Mutation in IR or IGF1R produces features of long-lived mice while maintaining metabolic health	50
Development of a humanized mouse model with functional human materno-fetal interface immunity	50
Dysregulated immunologic landscape of the early host response in melioidosis	50
The timing of auditory sensory deficits in Norrie disease has implications for therapeutic intervention	50
Lipidomic profiling of human adiposomes identifies specific lipid shifts linked to obesity and cardiometabolic risk	49
CD11c+ myeloid cell exosomes reduce intestinal inflammation during colitis	49
Lymphatic disorders caused by mosaic, activating KRAS variants respond to MEK inhibition	49
A dominant pathogenic MEFV mutation causes atypical pyrin-associated periodic syndromes	49
Endothelial-derived FABP4 constitutes the majority of basal circulating hormone and regulates lipolysis-driven insulin secretion	48
Longitudinal analysis of T cell receptor repertoires reveals shared patterns of antigen-specific response to SARS-CoV-2 infection	48
Human IL-6 fosters long-term engraftment of patient-derived disease-driving myeloma cells in immunodeficient mice	48
Prenatal alcohol exposure is associated with altered feto-placental blood flow and sex-specific placental changes	47
NSD1-916aa encoded by CircNSD1 contributes to AKI-to-CKD transition through inducing ferroptosis in tubular epithelial cells	47
Intragraft memory-like CD127hiCD4+Foxp3+ Tregs maintain transplant tolerance	47
Tubulin tyrosine ligase variant perturbs microtubule tyrosination, causing hypertrophy in patient-specific and CRISPR gene-edited iPSC-cardiomyocytes	47
Inhibition of the angiotensin-converting enzyme N-terminal catalytic domain prevents endogenous opioid degradation in brain tissue	47
Pericentrin deficiency in smooth muscle cells augments atherosclerosis through HSF1-driven cholesterol biosynthesis and PERK activation	47
Elevated apolipoprotein C3 augments diabetic kidney disease and associated atherosclerosis in type 2 diabetes	47
New insights into an old question: can the MD-PhD physician-scientist pipeline be improved?	46
Site-1 protease–mediated cholesterol metabolism is essential for lymphatic development in mice	46

Cleavage of N-terminus of polycystin-1 increases calcium permeability of polycystin-1/2 receptor channel complexes	46
Enhancing DC cancer vaccine by allogeneic MHC class II expression and Treg depletion	46
Mutational landscape of atherosclerotic plaques reveals large clonal cell populations	46
hsa-miRNA-548v controls the viscoelastic properties of human cardiomyocytes and improves their relaxation rates	46
The hepatokine TSK maintains myofiber integrity and exercise endurance and contributes to muscle regeneration	45
Caspase-4/11 promotes hyperlipidemia and chronic kidney disease-accelerated vascular inflammation by enhancing trained immunity	45
A heterozygous LAMA5 variant may contribute to slowly progressive, vinculin-enhanced familial FSGS and pulmonary defects	45
Mitochondrial and NAD+ metabolism predict recovery from acute kidney injury in a diverse mouse population	45
Intimomedial tears of the aorta heal by smooth muscle cell–mediated fibrosis without atherosclerosis	45
Evidence of a Sjögren’s disease–like phenotype following COVID-19 in mice and humans	44
Profound reduction of HIV-1 reservoir cells over 3 decades of antiretroviral therapy started in early infancy	44
Anti-CELA1 antibody KF4 prevents emphysema by inhibiting stretch-mediated remodeling	44
Focusing HIV-1 Gag T cell responses to highly conserved regions by DNA vaccination in HVTN 119	43
Immunological landscape of human lymphoid explants during measles virus infection	43
Single-cell landscape analysis unravels molecular programming of the human B cell compartment in chronic GVHD	43
Rapamycin immunomodulation utilizes time-dependent alterations of lymph node architecture, leukocyte trafficking, and gut microbiome	43
Horizontal transmission of gut microbiota attenuates mortality in lung fibrosis	43
Immune and epithelial determinants of age-related risk and alveolar injury in fatal COVID-19	43
Sorting nexin 10 sustains PDGF receptor signaling in glioblastoma stem cells via endosomal protein sorting	42
Differential histone acetylation and super-enhancer regulation underlie melanoma cell dedifferentiation	42
Mitochondria-sequestered Aβ renders synaptic mitochondria vulnerable in the elderly with a risk of Alzheimer disease	42
Longitudinal trajectories of branched chain amino acids through young adulthood and diabetes in later life	42
Angiopoietin-like 3 monomers are abundant in human plasma but areunable to inhibit endothelial lipase	42
Transcriptional signature of induced neurons differentiates virologically suppressed people with HIV from people without HIV	42
Combination therapy with remdesivir and monoclonal antibodies protects nonhuman primates against advanced Sudan virus disease	42
Duration of viral shedding and culture positivity with postvaccination SARS-CoV-2 delta variant infections	42
IL-15 reprogramming compensates for NK cell mitochondrial dysfunction in HIV-1 infection	41
Longitudinal associations of insulin resistance with change in bone mineral density in midlife women	41
mTOR inhibition overcomes RSK3-mediated resistance to BET inhibitors in small cell lung cancer	41
Outpatient COVID-19 convalescent plasma recipient antibody thresholds correlated to reduced hospitalizations within a randomized trial	41
First-in-class multifunctional TYMS nonclassical antifolate inhibitor with potent in vivo activity that prolongs survival	41
Histone demethylase JARID1C/KDM5C regulates Th17 cells by increasing IL-6 expression in diabetic plasmacytoid dendritic cells	41
Protein kinase G2 activation restores Wnt signaling and bone mass in glucocorticoid-induced osteoporosis in mice	41
FGF receptors mediate cellular senescence in the cystic fibrosis airway epithelium	41
Responders to low-dose ATG induce CD4+ T cell exhaustion in type 1 diabetes	40
SPOP mutations increase PARP inhibitor sensitivity via CK2/PIAS1/SPOP axis in prostate cancer	40
HIF1A-dependent induction of alveolar epithelial PFKFB3 dampens acute lung injury	40
Regulation of human and mouse bystander T cell activation responses by PD-1	40
Allele-specific silencing of the gain-of-function mutation in Huntington’s disease using CRISPR/Cas9	40
HIV-1–infected T cell clones are shared across cerebrospinal fluid and blood during ART	39
CAVIN3 deficiency promotes vascular normalization in ocular neovascular disease via ERK/JAG1 signaling pathway	39
A single-cell atlas of the myometrium in human parturition	39
ST6GAL1 sialyltransferase promotes acinar to ductal metaplasia and pancreatic cancer progression	39
Computational estimates of annular diameter reveal genetic determinants of mitral valve function and disease	39
Atypical response to bacterial coinfection and persistent neutrophilic bronchoalveolar inflammation distinguish critical COVID-19 from influenza	39
Hepatic FASN deficiency differentially affects nonalcoholic fatty liver disease and diabetes in mouse obesity models	39
A versatile laser-induced porcine model of outer retinal and choroidal degeneration for preclinical testing	39
Islet transplantation into brown adipose tissue can delay immune rejection	39
Filaggrin loss-of-function variants are associated with atopic dermatitis phenotypes in a diverse, early-life prospective cohort	39
Spatial transcriptomics reveals immune-stromal crosstalk within the synovium of patients with juvenile idiopathic arthritis	38
Epithelial Gab1 calibrates RIPK3-dependent necroptosis to prevent intestinal inflammation	38
Anoctamin-5 deficiency enhances ATG9A-dependent autophagy, inducing osteogenesis and gnathodiaphyseal dysplasia–like bone formation	38
Multiantigen pan-sarbecovirus DNA vaccines generate protective T cell immune responses	38
Evofosfamide for the treatment of human papillomavirus-negative head and neck squamous cell carcinoma	38
Inhibition of ceramide accumulation in AdipoR1–/– mice increases photoreceptor survival and improves vision	37
Catalytic isoforms of AMP-activated protein kinase differentially regulate IMPDH activity and photoreceptor neuron function	37
Perivascular inflammation in the progression of aortic aneurysms in Marfan syndrome	37
Thyroidal expression of ER molecular chaperone GRP170 is required for efficient TSH-mediated thyroid hormone synthesis	37
Dichloroacetate improves mitochondrial function, physiology, and morphology in FBXL4 disease models	37
An immunosuppressed microenvironment distinguishes lateral ventricle–contacting glioblastomas	36
S-nitrosylation attenuates pregnane X receptor hyperactivity and acetaminophen-induced liver injury	36
Mechanisms underlying age-associated exacerbation of pulmonary veno-occlusive disease	36
Endothelial response to blood-brain barrier disruption in the human brain	36
CCL3 in the bone marrow microenvironment causes bone loss and bone marrow adiposity in aged mice	36
Myocardial lipin1 protects the heart against ischemic injury by preserving lipid homeostasis	36
Restoring calcium homeostasis in Purkinje cells arrests neurodegeneration and neuroinflammation in the ARSACS mouse model	36
Intergenic sequences harboring potential enhancer elements contribute to Axenfeld-Rieger syndrome by regulating PITX2	35
Single-nucleus RNA-Seq reveals singular gene signatures of human ductal cells during adaptation to insulin resistance	35
A phase I study of autologous mesenchymal stromal cells for severe steroid-dependent nephrotic syndrome	35
In vivo AAV9-Myo7a gene rescue restores hearing and cholinergic efferent innervation in inner hair cells	35
Transcriptome and microbiome-immune changes across preinvasive and invasive anal cancer lesions	35
Piperlongumine overcomes osimertinib resistance via governing ubiquitination-modulated Sp1 turnover	35
ADAM17-mediated EGFR ligand shedding directs macrophage-promoted cancer cell invasion	35
β-Catenin disruption decreases macrophage exosomal α-SNAP and impedes Treg differentiation in acute liver injury	35
Persistent hepatic IFN system activation in HBV-HDV infection determines viral replication dynamics and therapeutic response	35
Effects of FGF21, soluble TGFBR2, and environmental temperature on metabolic dysfunction in lipodystrophic mice	35
SARA suppresses myofibroblast precursor transdifferentiation in fibrogenesis in a mouse model of scleroderma	35
Predictive value of TCR Vβ-Jβ profile for adjuvant gefitinib in EGFR mutant NSCLC from ADJUVANT-CTONG 1104 trial	35
PTP1B inhibitors protect against acute lung injury and regulate CXCR4 signaling in neutrophils	35
SARS-CoV-2 infection of sustentacular cells disrupts olfactory signaling pathways	34

Cross-species single-cell analysis uncovers the immunopathological mechanisms associated with IgA nephropathy progression	34
Functional Pdgfra fibroblast heterogeneity in normal and fibrotic mouse lung	34
HIV viral transcription and immune perturbations in the CNS of people with HIV despite ART	34
Single-cell RNA-Seq of human esophageal epithelium in homeostasis and allergic inflammation	34
Improved mitochondrial function in the hearts of sarcolipin-deficient dystrophin and utrophin double-knockout mice	34
suPAR links a dysregulated immune response to tissue inflammation and sepsis-induced acute kidney injury	34
Identification and validation of a T cell receptor targeting KRAS G12V in HLA-A*11:01 pancreatic cancer patients	33
Consecutive BNT162b2 mRNA vaccination induces short-term epigenetic memory in innate immune cells	33
Notch-mediated hepatocyte MCP-1 secretion causes liver fibrosis	33
Inflammation-induced TRIM21 represses hepatic steatosis by promoting the ubiquitination of lipogenic regulators	33
SLC6A19 inhibition facilitates urinary neutral amino acid excretion and lowers plasma phenylalanine	33
Circulating extracellular vesicles in human cardiorenal syndrome promote renal injury in a kidney-on-chip system	33
Spatiotemporal mapping of immune and stem cell dysregulation after volumetric muscle loss	32
IFN-λ uniquely promotes CD8 T cell immunity against SARS-CoV-2 relative to type I IFN	32
Cord blood proteomics identifies biomarkers of early-onset neonatal sepsis	32
Deletion of Ptpn2 in B cells promotes autoimmunity via TLR and JAK/STAT signaling	32
β Cell mass expansion during puberty involves serotonin signaling and determines glucose homeostasis in adulthood	32
Group IIA secreted phospholipase A2 controls skin carcinogenesis and psoriasis by shaping the gut microbiota	32
Orai1 calcium channel inhibition prevents progression of chronic pancreatitis	32
HSPA12A maintains aerobic glycolytic homeostasis and Histone3 lactylation in cardiomyocytes to attenuate myocardial ischemia/reperfusion injury	32
Isolevuglandins disrupt PU.1-mediated C1q expression and promote autoimmunity and hypertension in systemic lupus erythematosus	32
Rapid systemic spread and minimal immune responses following SIVsab intrarectal transmission in African green monkeys	32
Preclinical assessment of oral TLR7 agonist SA-5 in a nonhuman primate model	32
Human immune phenotyping reveals accelerated aging in type 1 diabetes	32
Involvement of impaired carnitine-induced fatty acid oxidation in experimental and human diabetic kidney disease	32
The gut microbiome enhances breast cancer immunotherapy following bariatric surgery	32
Uric acid formation is driven by crosstalk between skeletal muscle and other cell types	32
Preservation of naive-phenotype CD4+ T cells after vaccination contributes to durable immunity	32
CD34hi subset of synovial fibroblasts contributes to fibrotic phenotype of human knee osteoarthritis	32
The EMT factor ZEB1 paradoxically inhibits EMT in BRAF-mutant carcinomas	31
Hedgehog activation promotes osteogenic fates of growth plate resting zone chondrocytes through transient clonal competency	31
H1N1 challenge results in rapid recall of stem-specific immunity in HA stem nanoparticle–vaccinated newborn monkeys	31
Lack of myotubularin phosphatase activity is the main cause of X-linked myotubular myopathy	31
DAB2IP loss in luminal a breast cancer leads to NF-κB–associated aggressive oncogenic phenotypes	31
Deciphering the tumor microenvironment cell–infiltrating landscape reveals microenvironment subtypes and therapeutic potentials for nonsquamous NSCLC	31
Modeling skeletal dysplasia in Hurler syndrome using patient-derived bone marrow osteoprogenitor cells	31
A role for the transcriptional coregulator RIP140 in the control of muscle endurance fitness	31
Association of oxidized ApoB and oxidized ApoA-I with high-risk coronary plaque features in cardiovascular disease	31
Expansion of the HSV-2–specific T cell repertoire in skin after immunotherapeutic HSV-2 vaccine	30
DDR1 contributes to kidney inflammation and fibrosis by promoting the phosphorylation of BCR and STAT3	30
Bioactive extracellular vesicles from a subset of endothelial progenitor cells rescue retinal ischemia and neurodegeneration	30
Endothelial PRMT5 plays a crucial role in angiogenesis after acute ischemic injury	30
The aberrant tonsillar microbiota modulates autoimmune responses in rheumatoid arthritis	30
Chronic pharmacologic manipulation of dopamine transmission ameliorates metabolic disturbance in Trappc9-linked brain developmental syndrome	30
Oxygen-carrying nanoemulsions and respiratory hyperoxia eliminate tumor hypoxia–induced immunosuppression	30
ABT1 modifies SMARD1 pathology via interactions with IGHMBP2 and stimulation of ATPase and helicase activity	30
4PBA reduces growth deficiency in osteogenesis imperfecta by enhancing transition of hypertrophic chondrocytes to osteoblasts	30
Hypercapnia alters stroma-derived Wnt production to limit β-catenin signaling and proliferation in AT2 cells	30
Ebola virus protein VP40 stimulates IL-12– and IL-18–dependent activation of human natural killer cells	30
KLF4 is a therapeutically tractable brake on fibroblast activation that promotes resolution of pulmonary fibrosis	30
Intraperitoneal injection of class A TLR9 agonist enhances anti–PD-1 immunotherapy in colorectal peritoneal metastases	29
LIN28B promotes cell invasion and colorectal cancer metastasis via CLDN1 and NOTCH3	29
Mitochondrial β-oxidation of adipose-derived fatty acids by osteoblasts fuels parathyroid hormone–induced bone formation	29
Loss of ATRX promotes aggressive features of osteosarcoma with increased NF-κB signaling and integrin binding	29
iGATE analysis improves the interpretability of single-cell immune landscape of influenza infection	29
Atrial fibrillation–induced neurocognitive and vascular dysfunction is averted by mitochondrial oxidative stress reduction	29
Temporal development of T cell receptor repertoires during childhood in health and disease	29
Evaluating precision medicine approaches for gene therapy in patient-specific cellular models of Bietti crystalline dystrophy	29
A peptide blocking the ADORA1-neurabin interaction is anticonvulsant and inhibits epilepsy in an Alzheimer’s model	29
The ACTH test fails to diagnose adrenal insufficiency and augments cytokine production in sepsis	29
Go, Flight	29
Ancestry-based differences in the immune phenotype are associated with lupus activity	29
NEXN regulates vascular smooth muscle cell phenotypic switching and neointimal hyperplasia	29
Keratinocyte-derived cytokine TSLP promotes growth and metastasis of melanoma by regulating the tumor-associated immune microenvironment	29
The receptor BLT1 is essential on neutrophils in a mouse model of mucous membrane pemphigoid	29
Individual transcriptomic response to strength training for patients with myotonic dystrophy type 1	29
AI-assisted discovery of an ethnicity-influenced driver of cell transformation in esophageal and gastroesophageal junction adenocarcinomas	28
Label-free single-cell phenotyping to determine tumor cell heterogeneity in pancreatic cancer in real time	28
ISG15/GRAIL1/CD3 axis influences survival of patients with esophageal adenocarcinoma	28
Transcriptional control of a collagen deposition and adhesion process that promotes lung adenocarcinoma growth and metastasis	28
SNRNP70 regulates the splicing of CD55 to promote osteosarcoma progression	28
FAP PET identifies earlycardiac molecular changesinduced by doxorubicin chemotherapy	28
A Notch/IL-21 signaling axis primes bone marrow T cell progenitor expansion	28
Histamine-induced RPS6 phosphorylation in dendritic cells is associated with the severity of peanut allergic reactions	28
Circular RNA Cdr1as inhibits proliferation and delays injury-induced regeneration of the intestinal epithelium	28
Adjuvant COX inhibition augments STING signaling and cytolytic T cell infiltration in irradiated 4T1 tumors	28
Plasma cells in human pancreatic ductal adenocarcinoma secrete antibodies against self-antigens	28
Chemotherapy delivery time affects treatment outcomes of female patients with diffuse large B cell lymphoma	27
Antisense oligonucleotide therapy for KCNT1 encephalopathy	27
A therapeutic HBV vaccine containing a checkpoint modifier enhances CD8+ T cell and antiviral responses	27
Lipid metabolism analysis reveals that DGAT1 regulates Th17 survival by controlling lipid peroxidation in uveitis	27
New Pseudomonas infections drive Pf phage transmission in CF airways	27
Spheroids as a model for endometriotic lesions	27
A miRNA/CXCR4 signaling axis impairs monopoiesis and angiogenesis in diabetic critical limb ischemia	27
Intravital imaging of peritubular microcirculation impairment in cisplatin-induced acute kidney injury	27
CD8+ T cell–derived IL-13 increases macrophage IL-10 to resolve neuropathic pain	27
ERK hyperactivation in epidermal keratinocytes impairs intercellular adhesion and drives Grover disease pathology	27
Immunosurveillance shapes the emergence of neo-epitope landscapes of sarcomas, revealing prime targets for immunotherapy	27
Antibody-oligonucleotide conjugate achieves CNS delivery in animal models for spinal muscular atrophy	27
p53 maintains lineage fidelity during lung capillary injury-repair in neonatal hyperoxia	27
Reduction of mutant ATXN1 rescues premature death in a conditional SCA1 mouse model	27
Heterogeneity of thymic output in the elderly and its association with sex and smoking	27
Differential effects of HDAC8 targeting on Foxp3+ T-regulatory cells and effector T-cells promote anti-tumor immunity	27
Rapamycin rescues loss of function in blood-brain barrier–interacting Tregs	27
Subtype C HIV-1 reservoirs throughout the body in ART-suppressed individuals	27