JCI Insight

Article	Citations
Structural and functional analyses of a germline KRAS T50I mutation provide insights into Raf activation	217
A hypomorphic Mpi mutation unlocks an in vivo tool for studying global N-glycosylation deficiency	144
Immunotoxin-mediated depletion of Gag-specific CD8+ T cells undermines natural control of SIV	140
BPDCN MYB fusions regulate cell cycle genes, impair differentiation, and induce myeloid–dendritic cell leukemia	133
AXL inhibition suppresses early allograft monocyte-to-macrophage differentiation and prolongs allograft survival	108
Multicomponent parenteral lipid emulsions do not prevent liver injury in neonatal pigs with obstructive cholestasis	105
Characterization of anti-cancer therapy-induced microvascular dysfunction in breast cancer patients with proof-of-concept of targeted intervention	101
Bariatric surgery improves postprandial VLDL kinetics and restores insulin-mediated regulation of hepatic VLDL production	101
TIAM1 acts as an actin organization regulator to control adipose tissue–derived pericyte cell fate	96
Type I interferons and TGF-β cooperate to induce liver fibrosis during HIV-1 infection under antiretroviral therapy	88
Glucose-dependent insulinotropic polypeptide receptor signaling alleviates gut inflammation in mice	86
A dominant pathogenic MEFV mutation causes atypical pyrin-associated periodic syndromes	83
Myocardial ATP depletion detected noninvasively predicts sudden cardiac death risk in patients with heart failure	82
Pharmacological induction of MHC-I expression in tumor cells revitalizes T cell antitumor immunity	81
Sclerostin blockade inhibits bone resorption through PDGF receptor signaling in osteoblast lineage cells	80
Mineralocorticoid receptor antagonists and glucocorticoids differentially affect skeletal muscle inflammation and pathology in muscular dystrophy	79
Exploiting 4-1BB immune checkpoint to enhance the efficacy of oncolytic virotherapy for diffuse intrinsic pontine gliomas	77
The timing of auditory sensory deficits in Norrie disease has implications for therapeutic intervention	75
Steroid-sensitive nephrotic syndrome candidate gene CLVS1 regulates podocyte oxidative stress and endocytosis	73
CD11c+ myeloid cell exosomes reduce intestinal inflammation during colitis	71
Irx1 mechanisms for oral epithelial basal stem cell plasticity during reepithelialization after injury	70
Endothelial deletion of adipose triglyceride lipase protects against heart failure with preserved ejection fraction	70
Dipeptidase-1–knockout mice develop invasive tumors with features of microsatellite-unstable colorectal cancer	70
De novo variant in RING finger protein 213 causes systemic vasculopathy	69
The CLCA1/TMEM16A/Cl– current axis associates with H2S deficiency in diabetic kidney injury	69

Effects of SIPA1L1 on trabecular meshwork extracellular matrix protein accumulation and cellular phagocytosis in POAG	67
Longitudinal lipidomic profiles of left ventricular mass and left ventricular hypertrophy in American Indians	64
Autosomal-dominant macular dystrophy linked to a chromosome 17 tandem duplication	63
Constitutive deletion of the obscurin-Ig58/59 domains induces atrial remodeling and Ca2+-based arrhythmogenesis	62
Lipidomics of infant mesenchymal stem cells associate with the maternal milieu and child adiposity	62
LMAN1 serves as a cargo receptor for thrombopoietin	61
11C-Para-aminobenzoic acid PET imaging of S. aureus and MRSA infection in preclinical models and humans	61
Human IL-6 fosters long-term engraftment of patient-derived disease-driving myeloma cells in immunodeficient mice	61
Development of a humanized mouse model with functional human materno-fetal interface immunity	60
Urine proteomic signatures of kidney function decline after hospitalization	59
CD4+ and CD8+ T-cells are not the main driver of Lassa fever pathogenesis in macaques	58
Epac1–/– and Epac2–/– mice exhibit deficient epithelial Na+ channel regulation and impaired urinary Na+ conservation	58
Nociceptor neurons promote IgE class switch in B cells	57
Assemblies of JAG1 and JAG2 determine tracheobronchial cell fate in mucosecretory lung disease	57
Interferon-dependent signaling is critical for viral clearance in airway neutrophils	57
Hypoxia-activated prodrug and antiangiogenic therapies cooperatively treat pancreatic cancer but elicit immunosuppressive G-MDSC infiltration	56
Allergen induces pulmonary neuroendocrine cell hyperplasia in a model of asthma	56
EBAG9 controls CD8+ T cell memory formation responding to tumor challenge in mice	55
Lymph node CXCR5+ NK cells associate with control of chronic SHIV infection	55
Pregnancy dedifferentiates memory CD8+ T cells into hypofunctional cells with exhaustion-enriched programs	54
T cell metabolic reprogramming in acute kidney injury and protection by glutamine blockade	53
Lipidomic profiling of human adiposomes identifies specific lipid shifts linked to obesity and cardiometabolic risk	53
Recurrent moderate hypoglycemia accelerates the progression of Alzheimer’s disease through impairment of the TRPC6/GLUT3 pathway	52
Longitudinal analysis of T cell receptor repertoires reveals shared patterns of antigen-specific response to SARS-CoV-2 infection	52
Durability of ChAdOx1 nCoV-19 vaccination in people living with HIV	51
Intranodal expansion of follicular T helper cells in patients with multiple sclerosis	51
Lack of SPNS1 results in accumulation of lysolipids and lysosomal storage disease in mouse models	51
Allelic heterogeneity of TTNtv dilated cardiomyopathy can be modeled in adult zebrafish	51
Fibrotic lung disease inhibits immune responses to staphylococcal pneumonia via impaired neutrophil and macrophage function	51
Key patient demographics shape innate immune topography in noncritical hypoxic COVID-19 pneumonia	50
Regulation of selective class-switching provides long term therapeutic benefits for hay fever	50
Dysregulated immunologic landscape of the early host response in melioidosis	49
Ataxia and cerebellar hypoexcitability in a mouse model of SCN1B-linked Dravet syndrome	49
Coimmunomodulation of tumor and tumor-draining lymph nodes during in situ vaccination promotes antitumor immunity	49
Calcineurin inhibitors stimulate Kir4.1/Kir5.1 of the distal convoluted tubule to increase NaCl cotransporter	48
CNS-dominant human FMRP isoform rescues seizures, fear, and sleep abnormalities in Fmr1-KO mice	48
Fatal COVID-19 outcomes are associated with an antibody response targeting epitopes shared with endemic coronaviruses	48
Lymphatic disorders caused by mosaic, activating KRAS variants respond to MEK inhibition	48
UBE3A expression during early postnatal brain development is required for proper dorsomedial striatal maturation	48
Endothelial-derived FABP4 constitutes the majority of basal circulating hormone and regulates lipolysis-driven insulin secretion	48
Intragraft memory-like CD127hiCD4+Foxp3+ Tregs maintain transplant tolerance	47
Prenatal alcohol exposure is associated with altered feto-placental blood flow and sex-specific placental changes	47
Allele-specific silencing of the gain-of-function mutation in Huntington’s disease using CRISPR/Cas9	47
First-in-class multifunctional TYMS nonclassical antifolate inhibitor with potent in vivo activity that prolongs survival	47
Pericentrin deficiency in smooth muscle cells augments atherosclerosis through HSF1-driven cholesterol biosynthesis and PERK activation	47
Caspase-4/11 promotes hyperlipidemia and chronic kidney disease-accelerated vascular inflammation by enhancing trained immunity	47
Differential histone acetylation and super-enhancer regulation underlie melanoma cell dedifferentiation	46
Evidence of a Sjögren’s disease–like phenotype following COVID-19 in mice and humans	46
Focusing HIV-1 Gag T cell responses to highly conserved regions by DNA vaccination in HVTN 119	46
Responders to low-dose ATG induce CD4+ T cell exhaustion in type 1 diabetes	46

The hepatokine TSK maintains myofiber integrity and exercise endurance and contributes to muscle regeneration	45
Immune and epithelial determinants of age-related risk and alveolar injury in fatal COVID-19	45
A versatile laser-induced porcine model of outer retinal and choroidal degeneration for preclinical testing	45
Mutational landscape of atherosclerotic plaques reveals large clonal cell populations	44
New insights into an old question: can the MD-PhD physician-scientist pipeline be improved?	44
CAVIN3 deficiency promotes vascular normalization in ocular neovascular disease via ERK/JAG1 signaling pathway	44
Mitochondrial and NAD+ metabolism predict recovery from acute kidney injury in a diverse mouse population	44
Horizontal transmission of gut microbiota attenuates mortality in lung fibrosis	44
Intimomedial tears of the aorta heal by smooth muscle cell–mediated fibrosis without atherosclerosis	43
Profound reduction of HIV-1 reservoir cells over 3 decades of antiretroviral therapy started in early infancy	43
Multiantigen pan-sarbecovirus DNA vaccines generate protective T cell immune responses	43
NSD1-916aa encoded by CircNSD1 contributes to AKI-to-CKD transition through inducing ferroptosis in tubular epithelial cells	42
FGF receptors mediate cellular senescence in the cystic fibrosis airway epithelium	42
Elevated apolipoprotein C3 augments diabetic kidney disease and associated atherosclerosis in type 2 diabetes	42
Rapamycin immunomodulation utilizes time-dependent alterations of lymph node architecture, leukocyte trafficking, and gut microbiome	42
Immunological landscape of human lymphoid explants during measles virus infection	42
Histone demethylase JARID1C/KDM5C regulates Th17 cells by increasing IL-6 expression in diabetic plasmacytoid dendritic cells	41
Tubulin tyrosine ligase variant perturbs microtubule tyrosination, causing hypertrophy in patient-specific and CRISPR gene-edited iPSC-cardiomyocytes	41
Regulation of human and mouse bystander T cell activation responses by PD-1	41
HIV-1–infected T cell clones are shared across cerebrospinal fluid and blood during ART	41
Islet transplantation into brown adipose tissue can delay immune rejection	41
Enhancing DC cancer vaccine by allogeneic MHC class II expression and Treg depletion	41
Mitochondria-sequestered Aβ renders synaptic mitochondria vulnerable in the elderly with a risk of Alzheimer disease	40
Cleavage of N-terminus of polycystin-1 increases calcium permeability of polycystin-1/2 receptor channel complexes	40
Filaggrin loss-of-function variants are associated with atopic dermatitis phenotypes in a diverse, early-life prospective cohort	40
Protein kinase G2 activation restores Wnt signaling and bone mass in glucocorticoid-induced osteoporosis in mice	40
Anti-CELA1 antibody KF4 prevents emphysema by inhibiting stretch-mediated remodeling	40
ST6GAL1 sialyltransferase promotes acinar to ductal metaplasia and pancreatic cancer progression	39
Comparative route of administration studies using therapeutic siRNAs show widespread gene modulation in Dorset sheep	39
hsa-miRNA-548v controls the viscoelastic properties of human cardiomyocytes and improves their relaxation rates	39
Longitudinal trajectories of branched chain amino acids through young adulthood and diabetes in later life	39
Sorting nexin 10 sustains PDGF receptor signaling in glioblastoma stem cells via endosomal protein sorting	39
SPOP mutations increase PARP inhibitor sensitivity via CK2/PIAS1/SPOP axis in prostate cancer	39
HIF1A-dependent induction of alveolar epithelial PFKFB3 dampens acute lung injury	39
A heterozygous LAMA5 variant may contribute to slowly progressive, vinculin-enhanced familial FSGS and pulmonary defects	39
Duration of viral shedding and culture positivity with postvaccination SARS-CoV-2 delta variant infections	39
Outpatient COVID-19 convalescent plasma recipient antibody thresholds correlated to reduced hospitalizations within a randomized trial	39
mTOR inhibition overcomes RSK3-mediated resistance to BET inhibitors in small cell lung cancer	39
Computational estimates of annular diameter reveal genetic determinants of mitral valve function and disease	39
Site-1 protease–mediated cholesterol metabolism is essential for lymphatic development in mice	39
Angiopoietin-like 3 monomers are abundant in human plasma but are unable to inhibit endothelial lipase	39
A single-cell atlas of the myometrium in human parturition	38
Combination therapy with remdesivir and monoclonal antibodies protects nonhuman primates against advanced Sudan virus disease	38
Single-cell landscape analysis unravels molecular programming of the human B cell compartment in chronic GVHD	38
Atypical response to bacterial coinfection and persistent neutrophilic bronchoalveolar inflammation distinguish critical COVID-19 from influenza	38
IL-15 reprogramming compensates for NK cell mitochondrial dysfunction in HIV-1 infection	38
Hepatic FASN deficiency differentially affects nonalcoholic fatty liver disease and diabetes in mouse obesity models	38
Longitudinal associations of insulin resistance with change in bone mineral density in midlife women	38
Anoctamin-5 deficiency enhances ATG9A-dependent autophagy, inducing osteogenesis and gnathodiaphyseal dysplasia–like bone formation	37
Evofosfamide for the treatment of human papillomavirus-negative head and neck squamous cell carcinoma	37
Bioactive extracellular vesicles from a subset of endothelial progenitor cells rescue retinal ischemia and neurodegeneration	37
In vivo AAV9-Myo7a gene rescue restores hearing and cholinergic efferent innervation in inner hair cells	37
Rapid systemic spread and minimal immune responses following SIVsab intrarectal transmission in African green monkeys	37
Keratinocyte-derived cytokine TSLP promotes growth and metastasis of melanoma by regulating the tumor-associated immune microenvironment	36
Expansion of the HSV-2–specific T cell repertoire in skin after immunotherapeutic HSV-2 vaccine	36
Thyroidal expression of ER molecular chaperone GRP170 is required for efficient TSH-mediated thyroid hormone synthesis	36
The gut microbiome enhances breast cancer immunotherapy following bariatric surgery	36
Persistent hepatic IFN system activation in HBV-HDV infection determines viral replication dynamics and therapeutic response	36
Chronic pharmacologic manipulation of dopamine transmission ameliorates metabolic disturbance in Trappc9-linked brain developmental syndrome	36
The aberrant tonsillar microbiota modulates autoimmune responses in rheumatoid arthritis	36
Epithelial Gab1 calibrates RIPK3-dependent necroptosis to prevent intestinal inflammation	36
Dichloroacetate improves mitochondrial function, physiology, and morphology in FBXL4 disease models	36
Catalytic isoforms of AMP-activated protein kinase differentially regulate IMPDH activity and photoreceptor neuron function	36
Uric acid formation is driven by crosstalk between skeletal muscle and other cell types	36
Hypercapnia alters stroma-derived Wnt production to limit β-catenin signaling and proliferation in AT2 cells	35
4PBA reduces growth deficiency in osteogenesis imperfecta by enhancing transition of hypertrophic chondrocytes to osteoblasts	35
Ancestry-based differences in the immune phenotype are associated with lupus activity	35
Cord blood proteomics identifies biomarkers of early-onset neonatal sepsis	35
Orai1 calcium channel inhibition prevents progression of chronic pancreatitis	35
Hedgehog activation promotes osteogenic fates of growth plate resting zone chondrocytes through transient clonal competency	35
DAB2IP loss in luminal a breast cancer leads to NF-κB–associated aggressive oncogenic phenotypes	35
LIN28B promotes cell invasion and colorectal cancer metastasis via CLDN1 and NOTCH3	35
Identification and validation of a T cell receptor targeting KRAS G12V in HLA-A*11:01 pancreatic cancer patients	35
ABT1 modifies SMARD1 pathology via interactions with IGHMBP2 and stimulation of ATPase and helicase activity	35
Involvement of impaired carnitine-induced fatty acid oxidation in experimental and human diabetic kidney disease	35
Mechanisms underlying age-associated exacerbation of pulmonary veno-occlusive disease	35
KLF4 is a therapeutically tractable brake on fibroblast activation that promotes resolution of pulmonary fibrosis	35
HSPA12A maintains aerobic glycolytic homeostasis and Histone3 lactylation in cardiomyocytes to attenuate myocardial ischemia/reperfusion injury	34
Lack of myotubularin phosphatase activity is the main cause of X-linked Myotubular Myopathy	34
Improved mitochondrial function in the hearts of sarcolipin-deficient dystrophin and utrophin double-knockout mice	34

Association of oxidized ApoB and oxidized ApoA-I with high-risk coronary plaque features in cardiovascular disease	34
DDR1 contributes to kidney inflammation and fibrosis by promoting the phosphorylation of BCR and STAT3	34
Endothelial response to blood-brain barrier disruption in the human brain	34
Perivascular inflammation in the progression of aortic aneurysms in Marfan syndrome	34
Intergenic sequences harboring potential enhancer elements contribute to Axenfeld-Rieger syndrome by regulating PITX2	33
The EMT factor ZEB1 paradoxically inhibits EMT in BRAF-mutant carcinomas	33
Preservation of naive-phenotype CD4+ T cells after vaccination contributes to durable immunity	33
SARS-CoV-2 infection of sustentacular cells disrupts olfactory signaling pathways	33
Inhibition of the renin-angiotensin system causes concentric hypertrophy of renal arterioles in mice and humans	33
Effects of FGF21, soluble TGFBR2, and environmental temperature on metabolic dysfunction in lipodystrophic mice	33
Transcriptome and microbiome-immune changes across preinvasive and invasive anal cancer lesions	33
Functional Pdgfra fibroblast heterogeneity in normal and fibrotic mouse lung	33
CD34hi subset of synovial fibroblasts contributes to fibrotic phenotype of human knee osteoarthritis	32
Restoring calcium homeostasis in Purkinje cells arrests neurodegeneration and neuroinflammation in the ARSACS mouse model	32
IFN-λ uniquely promotes CD8 T cell immunity against SARS-CoV-2 relative to type I IFN	32
A role for the transcriptional coregulator RIP140 in the control of muscle endurance fitness	32
Cross-species single-cell analysis uncovers the immunopathological mechanisms associated with IgA nephropathy progression	32
Notch-mediated hepatocyte MCP-1 secretion causes liver fibrosis	32
NETs decorated with bioactive IL-33 infiltrate inflamed tissues and induce IFN-α production in patients with SLE	32
Evaluating precision medicine approaches for gene therapy in patient-specific cellular models of Bietti crystalline dystrophy	32
β-Catenin disruption decreases macrophage exosomal α-SNAP and impedes Treg differentiation in acute liver injury	32
Isolevuglandins disrupt PU.1-mediated C1q expression and promote autoimmunity and hypertension in systemic lupus erythematosus	32
Spatiotemporal mapping of immune and stem cell dysregulation after volumetric muscle loss	32
Inhibition of ceramide accumulation in AdipoR1–/– mice increases photoreceptor survival and improves vision	32
Ebola virus protein VP40 stimulates IL-12– and IL-18–dependent activation of human natural killer cells	32
Piperlongumine overcomes osimertinib resistance via governing ubiquitination-modulated Sp1 turnover	32
Deciphering the tumor microenvironment cell–infiltrating landscape reveals microenvironment subtypes and therapeutic potentials for nonsquamous NSCLC	31
CCL3 in the bone marrow microenvironment causes bone loss and bone marrow adiposity in aged mice	31
ADAM17-mediated EGFR ligand shedding directs macrophage-promoted cancer cell invasion	31
β Cell mass expansion during puberty involves serotonin signaling and determines glucose homeostasis in adulthood	31
Group IIA secreted phospholipase A2 controls skin carcinogenesis and psoriasis by shaping the gut microbiota	31
Inflammation-induced TRIM21 represses hepatic steatosis by promoting the ubiquitination of lipogenic regulators	31
HIV viral transcription and immune perturbations in the CNS of people with HIV despite ART	31
Oxygen-carrying nanoemulsions and respiratory hyperoxia eliminate tumor hypoxia–induced immunosuppression	31
SARA suppresses myofibroblast precursor transdifferentiation in fibrogenesis in a mouse model of scleroderma	31
Single-nucleus RNA-Seq reveals singular gene signatures of human ductal cells during adaptation to insulin resistance	31
PTP1B inhibitors protect against acute lung injury and regulate CXCR4 signaling in neutrophils	31
suPAR links a dysregulated immune response to tissue inflammation and sepsis-induced acute kidney injury	31
Single-cell RNA-Seq of human esophageal epithelium in homeostasis and allergic inflammation	30
A phase I study of autologous mesenchymal stromal cells for severe steroid-dependent nephrotic syndrome	30
Myocardial lipin1 protects the heart against ischemic injury by preserving lipid homeostasis	30
Circulating extracellular vesicles in human cardiorenal syndrome promote renal injury in a kidney-on-chip system	30
An immunosuppressed microenvironment distinguishes lateral ventricle–contacting glioblastomas	30
SLC6A19 inhibition facilitates urinary neutral amino acid excretion and lowers plasma phenylalanine	30
Human immune phenotyping reveals accelerated aging in type 1 diabetes	29
Osteopontin promotes age-related adipose tissue remodeling through senescence-associated macrophage dysfunction	29
Label-free single-cell phenotyping to determine tumor cell heterogeneity in pancreatic cancer in real time	29
Consecutive BNT162b2 mRNA vaccination induces short-term epigenetic memory in innate immune cells	29
Predictive value of TCR Vβ-Jβ profile for adjuvant gefitinib in EGFR mutant NSCLC from ADJUVANT-CTONG 1104 trial	29
Temporal development of T cell receptor repertoires during childhood in health and disease	29
p53 maintains lineage fidelity during lung capillary injury-repair in neonatal hyperoxia	29
Mitochondrial β-oxidation of adipose-derived fatty acids by osteoblasts fuels parathyroid hormone–induced bone formation	29
Endothelial PRMT5 plays a crucial role in angiogenesis after acute ischemic injury	29
Modeling skeletal dysplasia in Hurler syndrome using patient-derived bone marrow osteoprogenitor cells	29
IL-33 activates group 2 innate lymphoid cell expansion and modulates endometriosis	29
NEXN regulates vascular smooth muscle cell phenotypic switching and neointimal hyperplasia	29
Intraperitoneal injection of class A TLR9 agonist enhances anti–PD-1 immunotherapy in colorectal peritoneal metastases	29
S-nitrosylation attenuates pregnane X receptor hyperactivity and acetaminophen-induced liver injury	29
Lipid metabolism analysis reveals that DGAT1 regulates Th17 survival by controlling lipid peroxidation in uveitis	28
A Notch/IL-21 signaling axis primes bone marrow T cell progenitor expansion	28
Role of cGAS/STING pathway in aging and sexual dimorphism in diabetic kidney disease	28
The receptor BLT1 is essential on neutrophils in a mouse model of mucous membrane pemphigoid	28
The ACTH test fails to diagnose adrenal insufficiency and augments cytokine production in sepsis	28
SNRNP70 regulates the splicing of CD55 to promote osteosarcoma progression	28
Spheroids as a model for endometriotic lesions	28
Circular RNA Cdr1as inhibits proliferation and delays injury-induced regeneration of the intestinal epithelium	28
Individual transcriptomic response to strength training for patients with myotonic dystrophy type 1	28
The administration of exogenous HSP47 as a collagen-specific therapeutic approach	28
A peptide blocking the ADORA1-neurabin interaction is anticonvulsant and inhibits epilepsy in an Alzheimer’s model	28
A miRNA/CXCR4 signaling axis impairs monopoiesis and angiogenesis in diabetic critical limb ischemia	28
New Pseudomonas infections drive Pf phage transmission in CF airways	28
Parathyroid hormone 1 receptor signaling mediates breast cancer metastasis to bone in mice	28
Immunosurveillance shapes the emergence of neo-epitope landscapes of sarcomas, revealing prime targets for immunotherapy	27
Go, Flight	27
iGATE analysis improves the interpretability of single-cell immune landscape of influenza infection	27
Adjuvant COX inhibition augments STING signaling and cytolytic T cell infiltration in irradiated 4T1 tumors	27
FAP PET identifies early cardiac molecular changes induced by doxorubicin chemotherapy	27
ISG15/GRAIL1/CD3 axis influences survival of patients with esophageal adenocarcinoma	27
Rheumatoid arthritis synovial fluid induces JAK-dependent intracellular activation of human sensory neurons	27
Reduction of mutant ATXN1 rescues premature death in a conditional SCA1 mouse model	27
Rapamycin rescues loss of function in blood-brain barrier–interacting Tregs	27
Subtype C HIV-1 reservoirs throughout the body in ART-suppressed individuals	27
Intravital imaging of peritubular microcirculation impairment in cisplatin-induced acute kidney injury	27
Characterization of HMGA2 variants expands the spectrum of Silver-Russell syndrome	27
mTORC1 promotes malignant large cell/anaplastic histology and is a targetable vulnerability in SHH-TP53 mutant medulloblastoma	27
A therapeutic HBV vaccine containing a checkpoint modifier enhances CD8+ T cell and antiviral responses	27
Chemotherapy delivery time affects treatment outcomes of female patients with diffuse large B cell lymphoma	27
P2Y2 receptor decreases blood pressure by inhibiting ENaC	26
Targeting activin receptor–like kinase 7 ameliorates adiposity and associated metabolic disorders	26
Atrial fibrillation induced neurocognitive and vascular dysfunction is averted by mitochondrial oxidative stress reduction	26
Germline IgM predicts T cell immunity to Pneumocystis	26
Heterogeneity of thymic output in the elderly and its association with sex and smoking	26
T cell activation is insufficient to drive SIV disease progression	26
CTNND1 variants cause familial exudative vitreoretinopathy through the Wnt/cadherin axis	26
Antibody-oligonucleotide conjugate achieves CNS delivery in animal models for spinal muscular atrophy	26