Science Advances

Article	Citations
Test sensitivity is secondary to frequency and turnaround time for COVID-19 screening	767
Non-neuronal expression of SARS-CoV-2 entry genes in the olfactory system suggests mechanisms underlying COVID-19-associated anosmia	760
A single–cell type transcriptomics map of human tissues	736
Single-cell RNA-seq reveals ectopic and aberrant lung-resident cell populations in idiopathic pulmonary fibrosis	733
Air pollution and COVID-19 mortality in the United States: Strengths and limitations of an ecological regression analysis	670
Single-cell RNA sequencing reveals profibrotic roles of distinct epithelial and mesenchymal lineages in pulmonary fibrosis	581
More than 1000 rivers account for 80% of global riverine plastic emissions into the ocean	525
Agricultural diversification promotes multiple ecosystem services without compromising yield	457
The fungal collaboration gradient dominates the root economics space in plants	419
Wireless battery-free wearable sweat sensor powered by human motion	401
Shattering barriers toward clinically meaningful MSC therapies	377
Full-color fluorescent carbon quantum dots	373
Earth beyond six of nine planetary boundaries	361
High-entropy materials for catalysis: A new frontier	357
PM 2.5 polluters disproportionately and systemically affect people of color in the United States	323
Giant, unconventional anomalous Hall effect in the metallic frustrated magnet candidate, KV 3 Sb 5	308
Revisiting the PD-1 pathway	306
Conformational dynamics of SARS-CoV-2 trimeric spike glycoprotein in complex with receptor ACE2 revealed by cryo-EM	301
Integrated cascade nanozyme catalyzes in vivo ROS scavenging for anti-inflammatory therapy	300
CRISPR-Cas9 genome editing using targeted lipid nanoparticles for cancer therapy	296
Structure and inhibition of the SARS-CoV-2 main protease reveal strategy for developing dual inhibitors against M pro and cathepsin L	292
Falling living standards during the COVID-19 crisis: Quantitative evidence from nine developing countries	290
Activity profiling and crystal structures of inhibitor-bound SARS-CoV-2 papain-like protease: A framework for anti–COVID-19 drug design	290
The United States’ contribution of plastic waste to land and ocean	285
Regulating the absorption spectrum of polydopamine	276

Vaccine optimization for COVID-19: Who to vaccinate first?	272
3D printing of highly stretchable hydrogel with diverse UV curable polymers	264
23.7% Efficient inverted perovskite solar cells by dual interfacial modification	251
Hierarchically patterned self-powered sensors for multifunctional tactile sensing	250
Plastic waste to fuels by hydrocracking at mild conditions	247
Low-cost measurement of face mask efficacy for filtering expelled droplets during speech	245
Sustained oxygenation accelerates diabetic wound healing by promoting epithelialization and angiogenesis and decreasing inflammation	240
Microenvironment modulation of single-atom catalysts and their roles in electrochemical energy conversion	238
A highly stable lithium metal anode enabled by Ag nanoparticle–embedded nitrogen-doped carbon macroporous fibers	234
Reprogrammable shape morphing of magnetic soft machines	233
Controlling electrochemical growth of metallic zinc electrodes: Toward affordable rechargeable energy storage systems	229
Emergence of SARS-CoV-2 through recombination and strong purifying selection	228
Elusive consensus: Polarization in elite communication on the COVID-19 pandemic	225
Abrupt but smaller than expected changes in surface air quality attributable to COVID-19 lockdowns	222
Bioinspired mechano-photonic artificial synapse based on graphene/MoS 2 heterostructure	216
Efficient and stable inverted perovskite solar cells with very high fill factors via incorporation of star-shaped polymer	211
High-performance wearable thermoelectric generator with self-healing, recycling, and Lego-like reconfiguring capabilities	206
Ozone affects plant, insect, and soil microbial communities: A threat to terrestrial ecosystems and biodiversity	205
Learning the solution operator of parametric partial differential equations with physics-informed DeepONets	205
Regulation of macrophage polarization through surface topography design to facilitate implant-to-bone osteointegration	204
Mixed-dimensional MXene-hydrogel heterostructures for electronic skin sensors with ultrabroad working range	202
Exposing unsaturated Cu 1 -O 2 sites in nanoscale Cu-MOF for efficient electrocatalytic hydrogen evolution	201
In-sensor reservoir computing for language learning via two-dimensional memristors	200
Ultrasound Doppler-guided real-time navigation of a magnetic microswarm for active endovascular delivery	199
Minimally instrumented SHERLOCK (miSHERLOCK) for CRISPR-based point-of-care diagnosis of SARS-CoV-2 and emerging variants	198
Integrated proteomics reveals brain-based cerebrospinal fluid biomarkers in asymptomatic and symptomatic Alzheimer’s disease	197
The unfolding COVID-19 pandemic: A probability-based, nationally representative study of mental health in the United States	196
Ultrahigh specific strength in a magnesium alloy strengthened by spinodal decomposition	194
A unified vegetation index for quantifying the terrestrial biosphere	194
Distinct inflammatory profiles distinguish COVID-19 from influenza with limited contributions from cytokine storm	193
Residential solid fuel emissions contribute significantly to air pollution and associated health impacts in China	193
Recycling of multilayer plastic packaging materials by solvent-targeted recovery and precipitation	193
Molecularly soldered covalent organic frameworks for ultrafast precision sieving	191
Environmental exposure enhances the internalization of microplastic particles into cells	190
The direct drivers of recent global anthropogenic biodiversity loss	190
Landscapes of bacterial and metabolic signatures and their interaction in major depressive disorders	190
Conductance-stable liquid metal sheath-core microfibers for stretchy smart fabrics and self-powered sensing	189
Long-term (1990–2019) monitoring of forest cover changes in the humid tropics	188
From room temperature to harsh temperature applications: Fundamentals and perspectives on electrolytes in zinc metal batteries	188
Self-standing and flexible covalent organic framework (COF) membranes for molecular separation	187
Direct detection of circular polarized light in helical 1D perovskite-based photodiode	187
Differential effects of intervention timing on COVID-19 spread in the United States	186
Abrupt decline in tropospheric nitrogen dioxide over China after the outbreak of COVID-19	186
A smartphone-read ultrasensitive and quantitative saliva test for COVID-19	182
Partially exposed RuP 2 surface in hybrid structure endows its bifunctionality for hydrazine oxidation and hydrogen evolution catalysis	182
Direct probing of atomically dispersed Ru species over multi-edged TiO 2 for highly efficient photocatalytic hydrogen evolution	179
Slot-die coating large-area formamidinium-cesium perovskite film for efficient and stable parallel solar module	179
Metal-metal interactions in correlated single-atom catalysts	178
Intrapore energy barriers govern ion transport and selectivity of desalination membranes	177
Iodine reduction for reproducible and high-performance perovskite solar cells and modules	177

Model uncertainty, political contestation, and public trust in science: Evidence from the COVID-19 pandemic	177
Biodiversity intervention enhances immune regulation and health-associated commensal microbiota among daycare children	177
Crystallization in one-step solution deposition of perovskite films: Upward or downward?	175
Stimulus-responsive room temperature phosphorescence materials with full-color tunability from pure organic amorphous polymers	174
Self-powered electro-tactile system for virtual tactile experiences	174
Class I histone deacetylases (HDAC1–3) are histone lysine delactylases	174
Metasurface-based key for computational imaging encryption	173
Tip-induced flipping of droplets on Janus pillars: From local reconfiguration to global transport	170
Optical secret sharing with cascaded metasurface holography	170
Smart, soft contact lens for wireless immunosensing of cortisol	170
Wearable plasmonic-metasurface sensor for noninvasive and universal molecular fingerprint detection on biointerfaces	170
Confining Sn nanoparticles in interconnected N-doped hollow carbon spheres as hierarchical zincophilic fibers for dendrite-free Zn metal anodes	170
Tumor-specific cytolytic CD4 T cells mediate immunity against human cancer	170
A “Global Safety Net” to reverse biodiversity loss and stabilize Earth’s climate	170
A durable nanomesh on-skin strain gauge for natural skin motion monitoring with minimum mechanical constraints	168
An ultrathin rechargeable solid-state zinc ion fiber battery for electronic textiles	167
Expanding and optimizing 3D bioprinting capabilities using complementary network bioinks	167
A CRISPR-Cas autocatalysis-driven feedback amplification network for supersensitive DNA diagnostics	166
Exponential increase of plastic burial in mangrove sediments as a major plastic sink	166
Tissue-like skin-device interface for wearable bioelectronics by using ultrasoft, mass-permeable, and low-impedance hydrogels	166
Standalone real-time health monitoring patch based on a stretchable organic optoelectronic system	165
A century of observations reveals increasing likelihood of continental-scale compound dry-hot extremes	164
JAK inhibition reduces SARS-CoV-2 liver infectivity and modulates inflammatory responses to reduce morbidity and mortality	164
Holographic metasurface gas sensors for instantaneous visual alarms	163
Scalable integrated single-photon source	163
Directional liquid dynamics of interfaces with superwettability	162
A stretchable and strain-unperturbed pressure sensor for motion interference–free tactile monitoring on skins	161
Trisulfide bond–mediated doxorubicin dimeric prodrug nanoassemblies with high drug loading, high self-assembly stability, and high tumor selectivity	160
Highly selective and high-performance osmotic power generators in subnanochannel membranes enabled by metal-organic frameworks	160
A nonferrous ferroptosis-like strategy for antioxidant inhibition–synergized nanocatalytic tumor therapeutics	159
Meta-optics achieves RGB-achromatic focusing for virtual reality	158
A trusted node–free eight-user metropolitan quantum communication network	158
Plant rhizodeposition: A key factor for soil organic matter formation in stable fractions	157
Indium-antimony-halide single crystals for high-efficiency white-light emission and anti-counterfeiting	156
Restoration of seagrass habitat leads to rapid recovery of coastal ecosystem services	156
Systemic inequalities for LGBTQ professionals in STEM	155
Extracellular vesicle–encapsulated IL-10 as novel nanotherapeutics against ischemic AKI	155
Single-atom doping of MoS 2 with manganese enables ultrasensitive detection of dopamine: Experimental and computational approach	154
IRONSperm: Sperm-templated soft magnetic microrobots	154
Soft robotic origami crawler	154
Deep learning model to predict complex stress and strain fields in hierarchical composites	153
Engendering persistent organic room temperature phosphorescence by trace ingredient incorporation	153
Engineered ionizable lipid nanoparticles for targeted delivery of RNA therapeutics into different types of cells in the liver	152
Changes in global terrestrial live biomass over the 21st century	152
Highly energy-tunable quantum light from moiré-trapped excitons	151
Nonvolatile programmable silicon photonics using an ultralow-loss Sb 2 Se 3 phase change material	151
Bacteria-triggered tumor-specific thrombosis to enable potent photothermal immunotherapy of cancer	151
Hydroplastic foaming of graphene aerogels and artificially intelligent tactile sensors	150
Blood-brain barrier–penetrating siRNA nanomedicine for Alzheimer’s disease therapy	150
Three-dimensional printing of functionally graded liquid crystal elastomer	149
Molecular subtyping of Alzheimer’s disease using RNA sequencing data reveals novel mechanisms and targets	149
Nsp1 protein of SARS-CoV-2 disrupts the mRNA export machinery to inhibit host gene expression	148
Amorphization in extreme deformation of the CrMnFeCoNi high-entropy alloy	147
Color-pure red light-emitting diodes based on two-dimensional lead-free perovskites	147
Ultrafast self-gelling powder mediates robust wet adhesion to promote healing of gastrointestinal perforations	146
LRRK2 mediates tubulation and vesicle sorting from lysosomes	145
Three-dimensional, multifunctional neural interfaces for cortical spheroids and engineered assembloids	145
Satellite-based estimates of decline and rebound in China’s CO 2 emissions during COVID-19 pandemic	144
Two-qubit silicon quantum processor with operation fidelity exceeding 99%	143
Spatial heterogeneity and environmental predictors of permafrost region soil organic carbon stocks	143
Temperature-resilient solid-state organic artificial synapses for neuromorphic computing	143
A clicking confinement strategy to fabricate transition metal single-atom sites for bifunctional oxygen electrocatalysis	142
Partisan pandemic: How partisanship and public health concerns affect individuals’ social mobility during COVID-19	141
The distribution of biodiversity richness in the tropics	141
Crowdsourced air temperatures contrast satellite measures of the urban heat island and its mechanisms	140
Sequential vacuum-evaporated perovskite solar cells with more than 24% efficiency	140
Single-site Pt-doped RuO 2 hollow nanospheres with interstitial C for high-performance acidic overall water splitting	139
Dose-dependent effects of transcranial alternating current stimulation on spike timing in awake nonhuman primates	138
Amorphization mechanism of SrIrO 3 electrocatalyst: How oxygen redox initiates ionic diffusion and structural reorganization	137
3D bioprinting spatiotemporally defined patterns of growth factors to tightly control tissue regeneration	137
Precise correction of Duchenne muscular dystrophy exon deletion mutations by base and prime editing	137
Artificial tactile perception smart finger for material identification based on triboelectric sensing	137
YAP-mediated mechanotransduction tunes the macrophage inflammatory response	136
The carrier transition from Li atoms to Li vacancies in solid-state lithium alloy anodes	136
Structure-based drug designing and immunoinformatics approach for SARS-CoV-2	136
Estimation of incubation period distribution of COVID-19 using disease onset forward time: A novel cross-sectional and forward follow-up study	135
Molecular origin of negative component of Helmholtz capacitance at electrified Pt(111)/water interface	135
Blackbody-sensitive room-temperature infrared photodetectors based on low-dimensional tellurium grown by chemical vapor deposition	135
Ultrastrong lightweight compositionally complex steels via dual-nanoprecipitation	135
Purely satellite data–driven deep learning forecast of complicated tropical instability waves	134

GSH depletion liposome adjuvant for augmenting the photothermal immunotherapy of breast cancer	133
3D bioprinting dual-factor releasing and gradient-structured constructs ready to implant for anisotropic cartilage regeneration	133
A Janus emitter for passive heat release from enclosures	133
Comprehensive analysis of spatial architecture in primary liver cancer	132
Mitovesicles are a novel population of extracellular vesicles of mitochondrial origin altered in Down syndrome	132
The SARS-CoV-2 Spike variant D614G favors an open conformational state	132
Helicity-dependent photocurrents in the chiral Weyl semimetal RhSi	132
Caspase-8–dependent gasdermin D cleavage promotes antimicrobial defense but confers susceptibility to TNF-induced lethality	131
On-demand modulating afterglow color of water-soluble polymers through phosphorescence FRET for multicolor security printing	131
Wearable aptamer-field-effect transistor sensing system for noninvasive cortisol monitoring	131
Untethered small-scale magnetic soft robot with programmable magnetization and integrated multifunctional modules	131
Deep learning–based cell composition analysis from tissue expression profiles	130
Global waves synchronize the brain’s functional systems with fluctuating arousal	130
IL4-driven microglia modulate stress resilience through BDNF-dependent neurogenesis	130
Increasing precipitation variability on daily-to-multiyear time scales in a warmer world	130
Efficient high-throughput SARS-CoV-2 testing to detect asymptomatic carriers	129
Multilayered electronic transfer tattoo that can enable the crease amplification effect	129
Autonomous atmospheric water seeping MOF matrix	129
Hierarchically porous polyimide/Ti 3 C 2 T x film with stabl	128
Heterogeneous integration of rigid, soft, and liquid materials for self-healable, recyclable, and reconfigurable wearable electronics	128
Coral microbiome manipulation elicits metabolic and genetic restructuring to mitigate heat stress and evade mortality	128
Solar-assisted fabrication of large-scale, patternable transparent wood	127
Ultrafast, sensitive, and portable detection of COVID-19 IgG using flexible organic electrochemical transistors	126
ECM-mimetic immunomodulatory hydrogel for methicillin-resistant Staphylococcus aureus –infected chronic skin wound healing	126
A flexible multiplexed immunosensor for point-of-care in situ wound monitoring	126
Realization of an intrinsic ferromagnetic topological state in MnBi 8 Te 13	126
Biomolecule-guided cation regulation for dendrite-free metal anodes	125
Bioinspired high-power-density strong contractile hydrogel by programmable elastic recoil	125
100,000-spin coherent Ising machine	125
Ångstrom-scale silver particle–embedded carbomer gel promotes wound healing by inhibiting bacterial colonization and inflammation	125
Potency and timing of antiviral therapy as determinants of duration of SARS-CoV-2 shedding and intensity of inflammatory response	124
The unequal impact of parenthood in academia	124
Intrinsically stretchable electronics with ultrahigh deformability to monitor dynamically moving organs	124
Charged skyrmions and topological origin of superconductivity in magic-angle graphene	123
Digital light processing of liquid crystal elastomers for self-sensing artificial muscles	123
ROS-responsive chitosan-SS31 prodrug for AKI therapy via rapid distribution in the kidney and long-term retention in the renal tubule	123
Ionizable lipid nanoparticles for in utero mRNA delivery	123
Extinction and dawn of the modern world in the Carnian (Late Triassic)	122
High-performance pan-tactic polythioesters with intrinsic crystallinity and chemical recyclability	122
Erosion of global functional diversity across the tree of life	122
The costs and benefits of primary prevention of zoonotic pandemics	121
Organic and conservation agriculture promote ecosystem multifunctionality	121
Self-powered user-interactive electronic skin for programmable touch operation platform	121
Exploiting radiative cooling for uninterrupted 24-hour water harvesting from the atmosphere	121
Temperature dependence of elastic and plastic deformation behavior of a refractory high-entropy alloy	121
Positive interactions are common among culturable bacteria	120
Soft implantable drug delivery device integrated wirelessly with wearable devices to treat fatal seizures	120
Skin-interfaced microfluidic system with personalized sweating rate and sweat chloride analytics for sports science applications	120
Continuous on-body sensing for the COVID-19 pandemic: Gaps and opportunities	120
Revised chronology of central Tibet uplift (Lunpola Basin)	119
Genetically engineered cell membrane–coated nanoparticles for targeted delivery of dexamethasone to inflamed lungs	118
Evaluating the impact of long-term exposure to fine particulate matter on mortality among the elderly	118
Injectable hydrogel with MSNs/microRNA-21-5p delivery enables both immunomodification and enhanced angiogenesis for myocardial infarction therapy in pigs	117
Metasurface enabled quantum edge detection	117
The Human Proteoform Project: Defining the human proteome	117
Nonprecious transition metal nitrides as efficient oxygen reduction electrocatalysts for alkaline fuel cells	117
Mucosal immunity–mediated modulation of the gut microbiome by oral delivery of probiotics into Peyer’s patches	117
Rare earth element mobility in and around carbonatites controlled by sodium, potassium, and silica	117
Bias-preserving gates with stabilized cat qubits	117
Evolution and effects of the social-ecological system over a millennium in China’s Loess Plateau	117
Injectable hydrogel microspheres with self-renewable hydration layers alleviate osteoarthritis	116
An early warning approach to monitor COVID-19 activity with multiple digital traces in near real time	116
The evolution of white matter microstructural changes after mild traumatic brain injury: A longitudinal DTI and NODDI study	116
MCART1/SLC25A51 is required for mitochondrial NAD transport	116
Asphalt-related emissions are a major missing nontraditional source of secondary organic aerosol precursors	115
Multifunctional bioactive Nd-Ca-Si glasses for fluorescence thermometry, photothermal therapy, and burn tissue repair	115
Second life and recycling: Energy and environmental sustainability perspectives for high-performance lithium-ion batteries	115
Dynamic structural evolution of iron catalysts involving competitive oxidation and carburization during CO 2 hydrogenation	114
Biomimetic and flexible piezoelectric mobile acoustic sensors with multiresonant ultrathin structures for machine learning biometrics	114
Extraction of organic chemistry grammar from unsupervised learning of chemical reactions	114
Competing magnetic phases and fluctuation-driven scalar spin chirality in the kagome metal YMn 6 Sn 6	114
ChAdOx1 interacts with CAR and PF4 with implications for thrombosis with thrombocytopenia syndrome	114
The gill-oxygen limitation theory (GOLT) and its critics	113
How close are we to the temperature tipping point of the terrestrial biosphere?	113
A versatile hydrogel network–repairing strategy achieved by the covalent-like hydrogen bond interaction	113
Metabolically engineered stem cell–derived exosomes to regulate macrophage heterogeneity in rheumatoid arthritis	113
Snake extract–laden hemostatic bioadhesive gel cross-linked by visible light	112
Amazon rainforest photosynthesis increases in response to atmospheric dryness	112
Chromatin arranges in chains of mesoscale domains with nanoscale functional topography independent of cohesin	112
Acoustofluidic centrifuge for nanoparticle enrichment and separation	111
Electronic skin as wireless human-machine interfaces for robotic VR	111
A mathematical model of ctDNA shedding predicts tumor detection size	111
Inhalable Nanobody (PiN-21) prevents and treats SARS-CoV-2 infections in Syrian hamsters at ultra-low doses	111
Carbon-free and binder-free Li-Al alloy anode enabling an all-solid-state Li-S battery with high energy and stability	111
Strong self-trapping by deformation potential limits photovoltaic performance in bismuth double perovskite	111
Engineered neutrophil-derived exosome-like vesicles for targeted cancer therapy	111
Prospects of halide-based all-solid-state batteries: From material design to practical application	111
Understanding the electric and nonelectric field components of the cation effect on the electrochemical CO reduction reaction	111
Electrically compensated, tattoo-like electrodes for epidermal electrophysiology at scale	111
Development of ferroelectric nematic fluids with giant-ε dielectricity and nonlinear optical properties	111
Pooled CRISPR screening identifies m 6 A as a positive regulator of macrophage activation	111
NRF2 controls iron homeostasis and ferroptosis through HERC2 and VAMP8	110
Codelivery of CRISPR-Cas9 and chlorin e6 for spatially controlled tumor-specific gene editing with synergistic drug effects	110
Psychological inoculation improves resilience against misinformation on social media	110
Spectrally encoded single-pixel machine vision using diffractive networks	110