Science Advances

Papers
(The TQCC of Science Advances is 27. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)
ArticleCitations
Ultrafast tomograms in a flash2766
Saturn’s F ring is intermittently shepherded by Prometheus1008
Developmentally programmed histone H3 expression regulates cellular plasticity at the parental-to-early embryo transition591
Pfs230 domain 12 is a potent malaria transmission–blocking vaccine candidate490
Optimizing the timing of an end-of-outbreak declaration: Ebola virus disease in the Democratic Republic of the Congo428
Unmasking of the von Willebrand A-domain surface adhesin CglB at bacterial focal adhesions mediates myxobacterial gliding motility414
Spinning and corkscrewing of oceanic macroplankton revealed through in situ imaging414
Non-adapted bacterial infection suppresses plant reproduction407
Repeated climate-driven dispersal and speciation in peripheral populations of Pleistocene mastodons395
Artificial intelligence–enabled “inherited noninvasive intracellular recording” for prolonged monitoring of cardiac action potentials387
Pathways to concealed gun carrying377
Fluid dynamical pathways of airborne transmission while waiting in a line363
Signatures of speech and song: “Universal” links despite cultural diversity361
Dynamic control of molecular transport MXene transistor membranes356
Targeting transthyretin by one Cas9 variant with superfidelity and broad compatibility335
Editor’s note and erratum for the Research Article: “Unemployment and underemployment are causes of suicide”332
Erratum for the Research Article: “TREM2 inhibition triggers antitumor cell activity of myeloid cells in glioblastoma” by Sun et al .314
Erratum for the Research Article: “Oscillation of type IV pili regulated by the circadian clock in cyanobacterium Synechococcus elongatus PCC7942” by Zha309
Erratum for the Research Article: “SMAD4, activated by the TCR-triggered MEK/ERK signaling pathway, critically regulates CD8 + T cell cytotoxic funct301
Epidermal mutation accumulation in photodamaged skin is associated with skin cancer burden and can be targeted through ablative therapy295
Engineering is pregnant with possibilities286
Correlated x-ray fluorescence and ptychographic nano-tomography on Rembrandt’s The Night Watch reveals unknown lead “layer”277
The Plasmodium falciparum PPCS is a unique heteromeric complex with prokaryote-like activity and is a target of pantothenate analogs277
Atomic-scale physical unclonable functions in solids275
Removal of trace gases can both increase and decrease cloud droplet formation258
A plant NLR receptor activates auxin signaling through Aux/IAAs-ARF19 and YUC8-TIR1/AFBs to promote callose-mediated antiviral defense257
6mA-Sniper: Quantifying 6mA sites in eukaryotes at single-nucleotide resolution251
Targeting PD-1 + T cells with chimeric antigen receptors to reduce the HIV reservoir250
Metabolic reprogramming in Fanconi anemia: Evidence of compromised glucose oxidation, enhanced ketogenesis, and metabolic inflexibility248
Genome wide nucleosome landscape shapes 3D chromatin organization244
A DNA circuit that records molecular events241
Pan-cortical cellular imaging in freely behaving mice using a miniaturized micro-camera array microscope (mini-MCAM)240
CMOS-compatible electro-optical SRAM cavity device based on negative differential resistance240
Injectable shear-thinning hydrogels promote oligodendrocyte progenitor cell survival and remyelination in the central nervous system235
Electrostatic nano-mask patterned 180° domain walls in a ferroelectric film234
Navigating high-dimensional processing parameters in organic photovoltaics via a multitier machine learning framework234
Ancient genomes reveal Avar-Hungarian transformations in the 9th-10th centuries CE Carpathian Basin234
Sensory-motor circuit is a therapeutic target for dystonia musculorum mice, a model of hereditary sensory and autonomic neuropathy 6232
Munc13-1 couples DAG and Ca 2+ signaling to dynamic vesicle priming, synaptic short-term plasticity, and posttetanic potentiation232
Invariable resistance of conductive nanocomposite over 30% strain230
The super elongation complex drives transcriptional addiction in MYCN -amplified neuroblastoma229
Pancreatic tumor microenvironmental acidosis and hypoxia transform gold nanorods into cell-penetrant particles for potent radiosensitization228
Observation of dynamic nuclear polarization echoes227
Erratum for the Research Article “A multi-agentic framework for real-time, autonomous freeform metasurface design” by R. Lupoiu et al .221
Kir7.1 is the physiological target for hormones and steroids that regulate uteroplacental function220
Investigating charge accumulation mechanisms in organic materials via slow transient emission spectroscopy219
Autocatalytic assembly of a chimeric aminoacyl-RNA synthetase ribozyme215
Small effect of partial melt on electrical anomalies in the asthenosphere212
Laws about bodily damage originate from shared intuitions about the value of body parts210
Cpeb1 remodels cell type–specific translational program to promote fear extinction209
Early IGF-1 receptor inhibition in mice mimics preterm human brain disorders and reveals a therapeutic target209
The D614G mutation redirects SARS-CoV-2 spike to lysosomes and suppresses deleterious traits of the furin cleavage site insertion mutation208
Real-time observation of non-equilibrium phonon-electron energy and angular momentum flow in laser-heated nickel207
A poxvirus model reveals general correlates of antigen presentation and immunogenicity for viral CD8 + T cell epitopes204
Depolarization block in olfactory sensory neurons expands the dimensionality of odor encoding204
Beyond seizure control: Identifying deficits in cognitive networks in absence epilepsy203
Synergistic antioxidant and gene supplementation for high-efficacy retinitis pigmentosa therapy196
Phosphorylation of XPD drives its mitotic role independently of its DNA repair and transcription functions196
Phylogenetic tracing of midbrain-specific regulatory sequences suggests single origin of eubilaterian brains195
Imaging local diffusion in microstructures using NV-based pulsed field gradient NMR190
Bacterial communities co-develop with respiratory immunity early in life, linking dysbiosis to systemic monocyte signature and wheezing190
Structural and computational design of a SARS-CoV-2 spike antigen with improved expression and immunogenicity190
A universal oxygen scavenger for oxidase-based biosensors189
The molecular mechanism of sialic acid transport mediated by Sialin187
LC3-associated endocytosis and the functions of Rubicon and ATG16L1186
Cellular stiffness sensing through talin 1 in tissue mechanical homeostasis185
Long noncoding RNA DREAMer bridges the DREAM complex and E2f1 to regulate endoreplication in Drosophila185
Multicatalysis protocol enables direct and versatile enantioselective reductive transformations of secondary amides185
Water doping sodium battery electrolyte controls nanostructure, interactions, and electrochemical properties184
Notch signaling blockade links transcriptome heterogeneity in quiescent neural stem cells with reactivation routes and potential181
Real-time antiproton annihilation vertexing with submicrometer resolution181
Time-resolving state-specific molecular dissociation with XUV broadband absorption spectroscopy181
An evolutionary conserved neural mechanism for interpersonal coordination in primates181
A computational mechanism of cue-stimulus integration for pain in the brain180
RGMa collapses the neuronal actin barrier against disease-implicated protein and exacerbates ALS178
Unpacking the growth of global agricultural greenhouse gas emissions176
Considering intentional stratospheric dehydration for climate benefits175
Analysis of sloppiness in model simulations: Unveiling parameter uncertainty when mathematical models are fitted to data175
Dissecting abstract, modality-specific and experience-dependent coding of affect in the human brain174
Piezobiomimetic delivery nanosystem converts cold tumors to hot by parallel PANoptosis/STING activation in hepatocellular carcinoma173
Disaggregated machine learning via in-physics computing at radio frequency173
Proteome-wide computational analyses reveal links between protein condensate formation and RNA biology171
Bound chiral magnonic polariton states for ideal microwave isolation171
X-ray phase measurements by time-energy correlated photon pairs171
Endogenous retroviruses mediate transcriptional rewiring in response to oncogenic signaling in colorectal cancer171
Anabolic indices of matrix proteins identify regenerative small RNA intrinsic to human cartilage171
Abiotic molecular oxygen production—Ionic pathway from sulfur dioxide170
Driving forces of Antarctic krill abundance169
Dephosphorylation and ion binding in prokaryotic calcium transport166
A monolayer crystalline covalent network of polyoxometalate clusters165
Microsecond dynamics control the HIV-1 Envelope conformation165
Cerebrospinal fluid flow extends to peripheral nerves further unifying the nervous system164
Artificial biomarker-based feedback-regulated personalized and precise thrombolysis with lower hemorrhagic risk163
Spatial analysis of mitochondrial gene expression reveals dynamic translation hubs and remodeling in stress163
Flash annealing–engineered wafer-scale relaxor antiferroelectrics for enhanced energy storage performance162
Compressing slippery surface-assembled amphiphiles for tunable haptic energy harvesters161
AMPK-dependent phosphorylation of MTFR1L regulates mitochondrial morphology161
Real-space visualization of order-disorder transition in BaTiO 3161
Spatially resolved single-cell atlas of ascidian endostyle provides insight into the origin of vertebrate pharyngeal organs159
MiniXL: An open-source, large field-of-view epifluorescence miniscope enabling single-cell resolution and multi-region imaging in mice158
How leg muscles get to know who they are158
Alcaligenes faecalis corrects aberrant matrix metalloproteinase expression to promote reepithelialization of diabetic wounds157
Stretchable complementary integrated electronics based on elastic dual-type transistors156
Distributed interfacing by nanoscale photodiodes enables single-neuron light activation and sensory enhancement in 3D spinal explants156
Ultrapliable bioelectronic interface for mechanosensitive cardiac electrophysiology155
Targeting OXPHOS de novo purine synthesis as the nexus of FLT3 inhibitor–mediated synergistic antileukemic actions155
Neuromuscular embodiment of feedback control elements in Drosophila flight152
Liver endothelial zonation orchestrates hepatic steatosis onset through retinoic acid–regulated FGF1152
Buffering of genetic dominance by allele-specific protein complex assembly151
Development of xanthone derivatives as effective broad-spectrum antimicrobials: Disrupting cell wall and inhibiting DNA synthesis151
Structural and quantum chemical basis for OCP-mediated quenching of phycobilisomes150
Characterizing many-body dynamics with projected ensembles on a superconducting quantum processor150
Role of HAUS7 as a DOCK3 binding partner in facilitating axon regeneration150
Rise in broadly cross-reactive adaptive immunity against human β-coronaviruses in MERS-recovered patients during the COVID-19 pandemic150
An OsGLK1/2-DGP1/2/3 feedback module regulates rice photosynthesis and yield150
Gender composition predicts gender bias: A meta-reanalysis of hiring discrimination audit experiments147
Distributed sensing along fibers for smart clothing147
Complementary corticostriatal circuits orchestrate action repetition and switching147
Allospecific splenic Tr1 cells drive effector T cell exhaustion through up-regulated Areg-EGFR signaling to promote transplant tolerance147
Effect of cellular nutrient economy on the evolution of genome size in phytoplankton147
3D DNA origami pincers that multitask on giant unilamellar vesicles147
Regulation of PD-L1 through direct binding of cholesterol to CRAC motifs147
Sub- 1 / 10 exciton threshold lasers using stable self-charged perovskite quantum rods146
Above-twofold quantum super-resolution microscopy enabled by multiple idler passes with entangled biphotons146
Modularized microrobot with lock-and-detachable modules for targeted cell delivery in bile duct145
An artificial intelligence enabled chemical synthesis robot for exploration and optimization of nanomaterials145
DNA repair during nonreductional meiosis in the asexual rotifer Adineta vaga145
Bone-inspired stress-gaining elastomer enabled by dynamic molecular locking144
Inherent tendency of Synechococcus and heterotrophic bacteria for mutualism on long-term coexistence despite environmental interference144
All eukaryotic SMC proteins induce a twist of −0.6 at each DNA loop extrusion step144
A solid-to-solid metallic conversion electrochemistry toward 91% zinc utilization for sustainable aqueous batteries143
Enhanced Rap1 small GTPase activity in the ventral hippocampus drives stress-induced anxiety143
Molybdate uptake interplay with ROS tolerance modulates bacterial pathogenesis142
Clusters of lineage-specific genes are anchored by ZNF274 in repressive perinucleolar compartments142
Ag-doped non–imperfection-enabled uniform memristive neuromorphic device based on van der Waals indium phosphorus sulfide142
2D material exciton-polariton transport on 2D photonic crystals142
Predicting three-component reaction outcomes from ~40,000 miniaturized reactant combinations142
Synaptic vesicles that store monoamines and glutamate differ in protein composition141
Autologous human iPSC–derived alveolus-on-chip reveals early pathological events of Mycobacterium tuberculosis infection141
A radio pulsar phase from SGR J1935+2154 provides clues to the magnetar FRB mechanism140
A global internal tide modeling framework for improving satellite observations of fine-scale ocean circulation140
Structure and dynamics determine G protein coupling specificity at a class A GPCR140
Deep and dynamic metabolic and structural imaging in living tissues140
Magnetic fields and relativistic electrons fill entire galaxy cluster140
The genomic landscape of familial glioma138
Anthropogenic warming has ushered in an era of temperature-dominated droughts in the western United States138
Broadband photodetection of intense lasers via exciton-enhanced high-order multiphoton-absorption optoelectronics in 2D hybrid perovskite137
Diamond-based microwave quantum amplifier137
Multiplexed mapping of the interactome of GPCRs with receptor activity–modifying proteins137
Chaperone-mediated heterotypic phase separation regulates liquid-to-solid phase transitions of tau into amyloid fibrils137
Sensing spin wave excitations by spin defects in few-layer-thick hexagonal boron nitride137
Age-dependent acquisition of pathogenicity by SARS-CoV-2 Omicron BA.5137
VARP binds SNX27 to promote endosomal supercomplex formation on membranes136
Plasma-enhanced electronic textiles for energy harvesting136
Episodic reef growth in the Last Interglacial driven by competing influence of polar ice sheets to sea level rise136
Optical control of 4 f orbital state in rare-earth metals136
Enhancer dynamics: Unraveling the mechanism of transcriptional bursting135
Zika virus noncoding RNA cooperates with the viral protein NS5 to inhibit STAT1 phosphorylation and facilitate viral pathogenesis135
Coxsackievirus infection induces direct pancreatic β cell killing but poor antiviral CD8 + T cell responses134
Memristive floating-point Fourier neural operator network for efficient scientific modeling134
Transferring strongly reducing electrons to bidentate-adsorbed CO 2 for efficient and selective formate photosynthesis134
Pd/Xu-Phos-catalyzed asymmetric elimination of fully substituted enol triflates into axially chiral trisubstituted allenes134
Upward propagation of gigantic jets revealed by 3D radio and optical mapping131
Divergent synthesis of complex withanolides enabled by a scalable route and late-stage functionalization131
Hibiscus bullseyes reveal mechanisms controlling petal pattern proportions that influence plant-pollinator interactions131
Orbital angular momentum–driven multistate photomemory131
Inflammatory responses to acute carbon monoxide poisoning and the role of plasma gelsolin130
Ordered planar plating/stripping enables deep cycling zinc metal batteries130
Elder fish means more microplastics? Alaska pollock microplastic story in the Bering Sea130
Distinct armchair and zigzag charge transport through single polycyclic aromatics129
HfZrO-based synaptic resistor circuit for a Super-Turing intelligent system129
In vivo mapping of cellular resolution neuropathology in brain ischemia with diffusion MRI129
HIV-1 manipulates CD96 on CD4 + T cells to subvert antiviral immunity127
Motion Hologram: Jointly optimized hologram generation and motion planning for photorealistic 3D displays via reinforcement learning127
Rhombohedral-stacked bilayer transition metal dichalcogenides for high-performance atomically thin CMOS devices127
Stem cell mTOR signaling directs region-specific cell fate decisions during intestinal nutrient adaptation127
Low-waste, single-step, sustainable extraction of critical metals from deep-sea polymetallic nodules125
27-Hydroxycholesterol acts on estrogen receptor α expressed by POMC neurons in the arcuate nucleus to modulate feeding behavior125
Decoding paradoxical BOLD responses to transcranial ultrasound stimulation with concurrent optoacoustic magnetic resonance imaging125
Optical and electrical probing of plasmonic metal-molecule interactions125
Blind identification of the spinal cord output in humans with high-density electrode arrays implanted in muscles125
Liquid palladium for high-turnover carbon-carbon bond formation125
Correlated quantum machines beyond the standard second law124
Real-space investigation of polarons in hematite Fe 2 O 3124
Gating of hair cell Ca 2+ channels governs the activity of cochlear neurons124
Quantum imaging of the reconfigurable VO 2 synaptic electronics for neuromorphic computing124
How genomic insights into the evolutionary history of clouded leopards inform their conservation123
CysMP reveals metal ion–specific metalloproteomes and copper-regulated PGK1 activity in glycolysis123
Uncertainties too large to predict tipping times of major Earth system components from historical data123
Multiplexed CRISPR-Cas9 mutagenesis of rice PSBS1 noncoding sequences for transgene-free overexpression122
Separation and recycling of hydrofluorocarbon refrigerant mixtures with fluoropolymer-coated hollow fiber membranes122
Ideological bias in the production of research findings122
Valence electron concentration as key parameter to control the fracture resistance of refractory high-entropy carbides121
A conserved molecular template underlies color pattern diversity in estrildid finches121
Attosecond spectroscopy reveals spontaneous symmetry breaking in molecular photoionization121
The synovial environment steers cartilage deterioration and regeneration121
Daily turnover of active giant virus infection during algal blooms revealed by single-cell transcriptomics120
In vivo membrane engineering traps Gd-based MRI contrast agents for detecting microhepatocellular carcinoma120
GPCR-mediated calcium and cAMP signaling determines psychosocial stress susceptibility and resiliency120
GDF8 inhibition enhances musculoskeletal recovery and mitigates posttraumatic osteoarthritis following joint injury120
Inhibition of microbial deconjugation of micellar bile acids protects against intestinal permeability and liver injury119
Comediation of voltage gating and ion charge in MXene membrane for controllable and selective monovalent cation separation119
Broadband and high-speed terahertz wireless sensing via vertical-transport Dirac-source detector119
Synthesis of defect-rich La 2 O 2 CO 3 supports for enhanced CO 2 119
A printed luminescent flier inspired by plant seeds for eco-friendly physical sensing118
Efficient launching of shear phonons in photostrictive halide perovskites118
Healing of ischemic injury in the retina118
Designing a DNA synchronizer for compact single-rail DNA logic circuits118
RIPK1 inhibition reduces biliary injury and fibrosis in primary sclerosing cholangitis117
Cryo-EM visualization of DNA-PKcs structural intermediates in NHEJ117
Hidden white and black feather layers enhance plumage coloration in tanagers and other songbirds117
Direct observations of cross-scale wave-particle energy transfer in space plasmas117
Donor HLA-DQ genetic and functional divergence affect the control of BK polyoma virus infection after kidney transplantation117
A closed-loop catalytic nanoreactor system on a transistor117
Wnt signaling modulates mechanotransduction in the epidermis to drive hair follicle regeneration116
Oral iron sulfide prevents acute alcohol intoxication by initiating the endogenous multienzymatic antioxidant defense system116
Enhanced NF-κB activation via HIV-1 Tat-TRAF6 cross-talk116
Oxygen isotopes of anhydrous primary minerals show kinship between asteroid Ryugu and comet 81P/Wild2116
Emergence and reconfiguration of modular structure for artificial neural networks during continual familiarity detection116
Elucidating the characteristics and clonal evolutionary trajectory of influenza neuraminidase broadly reactive B cell115
Chromobacterium biopesticide overcomes insecticide resistance in malaria vector mosquitoes115
Low-dose metformin requires brain Rap1 for its antidiabetic action115
The extinct shark Otodus megalodon was a transoceanic superpredator: Inferences from 3D modeling115
Rac1 promotes kidney collecting duct repair by mechanically coupling cell morphology to mitotic entry115
Prebunking and credible source corrections increase election credibility: Evidence from the US and Brazil114
N -Heterocyclic carbene catalytic 1,2-boron migrative acylation accelerated by photocatalysis114
Global health risks lurking in livestock resistome114
A molecular switch controls assembly of bacterial focal adhesions114
Scalable generalized meta-spanners enabling parallel multitasking optical manipulation114
Biological export production controls upper ocean calcium carbonate dissolution and CO 2 buffer capacity114
Cold exposure stimulates cross-tissue metabolic rewiring to fuel glucose-dependent thermogenesis in brown adipose tissue114
Mechanistic insights into the roles of the UFM1 E3 ligase complex in ufmylation and ribosome-associated protein quality control113
Shear shock waves mediate haptic holography via focused ultrasound113
Engineered IL-7 synergizes with IL-12 immunotherapy to prevent T cell exhaustion and promote memory without exacerbating toxicity113
Size-dependent temporal decoupling of morphogenesis and transcriptional programs in pseudoembryos113
Unveiling cascading lag effects of wetland methane emissions: Evidence from Lake Chad in Africa112
Structural and mechanistic basis for the heterotetrameric benzaldehyde synthase from petunia112
The potassium transporter TaNHX2 interacts with TaGAD1 to promote drought tolerance via modulating stomatal aperture in wheat112
Attentional guidance through object associations in visual cortex112
Pathogenic variants in the human TONSL protein associated with SPONASTRIME dysplasia impair protein dimerization and DNA repair112
Diving into the vertical dimension of elasmobranch movement ecology111
Miniature battery-free epidural cortical stimulators111
Conserved sites on the influenza H1 and H3 hemagglutinin recognized by human antibodies111
Discovery of an autoinhibited conformation in mesotrypsin reveals a strategy for selective serine protease inhibition111
Ultrastrong Staphylococcus aureus adhesion to human skin: Calcium as a key regulator of noncovalent interactions111
Articular fibrocartilage-targeted therapy by microtubule stabilization111
Exosome-mediated delivery of Cas9 ribonucleoprotein complexes for tissue-specific gene therapy of liver diseases111
Monocytic MDSCs exhibit superior immune suppression via adenosine and depletion of adenosine improves efficacy of immunotherapy110
A two-stage mantle plume-sagduction origin of Archean continental crust revealed by water and oxygen isotopes of TTGs110
Seeing through arthropod eyes: An AI-assisted, biomimetic approach for high-resolution, multi-task imaging110
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