Science Advances

Papers
(The TQCC of Science Advances is 27. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)
ArticleCitations
Microsecond dynamics control the HIV-1 Envelope conformation1147
Genome wide nucleosome landscape shapes 3D chromatin organization1090
An annually resolved 5700-year storm archive reveals drivers of Caribbean cyclone frequency548
Quantized critical supercurrent in SrTiO 3 -based quantum point contacts440
Truncated jarid2 and kdm6b transcripts are associated with temperature-induced sex reversal during development in a dragon lizard382
A molecular switch controls assembly of bacterial focal adhesions354
Upward propagation of gigantic jets revealed by 3D radio and optical mapping331
Donor HLA-DQ genetic and functional divergence affect the control of BK polyoma virus infection after kidney transplantation314
Kir7.1 is the physiological target for hormones and steroids that regulate uteroplacental function297
HfZrO-based synaptic resistor circuit for a Super-Turing intelligent system289
Development of xanthone derivatives as effective broad-spectrum antimicrobials: Disrupting cell wall and inhibiting DNA synthesis262
Fast cortical dynamics encode tactile grating orientation during active touch256
Dissecting abstract, modality-specific and experience-dependent coding of affect in the human brain253
DNA repair during nonreductional meiosis in the asexual rotifer Adineta vaga253
Unmasking of the von Willebrand A-domain surface adhesin CglB at bacterial focal adhesions mediates myxobacterial gliding motility248
Distinct armchair and zigzag charge transport through single polycyclic aromatics247
Diversification of the ruminant skull along an evolutionary line of least resistance242
Phylogenetic tracing of midbrain-specific regulatory sequences suggests single origin of eubilaterian brains242
Miniature color camera via flat hybrid meta-optics241
Developmentally programmed histone H3 expression regulates cellular plasticity at the parental-to-early embryo transition241
Diamond-based microwave quantum amplifier241
Injectable shear-thinning hydrogels promote oligodendrocyte progenitor cell survival and remyelination in the central nervous system239
The extinct shark Otodus megalodon was a transoceanic superpredator: Inferences from 3D modeling231
Considering intentional stratospheric dehydration for climate benefits230
Retromer stabilizes transient membrane insertion of L2 capsid protein during retrograde entry of human papillomavirus228
Ciliopathy protein HYLS1 coordinates the biogenesis and signaling of primary cilia by activating the ciliary lipid kinase PIPKIγ226
Photoactivated voltage imaging in tissue with an archaerhodopsin-derived reporter222
Miniature battery-free epidural cortical stimulators222
Engineering is pregnant with possibilities211
Invariable resistance of conductive nanocomposite over 30% strain210
Clusters of lineage-specific genes are anchored by ZNF274 in repressive perinucleolar compartments209
Erratum for the Research Article: “Tumor to normal single-cell mRNA comparisons reveal a pan-neuroblastoma cancer cell”207
An outsized role for the Labrador Sea in the multidecadal variability of the Atlantic overturning circulation207
Pathways to concealed gun carrying206
Multiplexed CRISPR-Cas9 mutagenesis of rice PSBS1 noncoding sequences for transgene-free overexpression206
27-Hydroxycholesterol acts on estrogen receptor α expressed by POMC neurons in the arcuate nucleus to modulate feeding behavior204
All eukaryotic SMC proteins induce a twist of −0.6 at each DNA loop extrusion step203
Small effect of partial melt on electrical anomalies in the asthenosphere201
Erratum for the Research Article: “Oscillation of type IV pili regulated by the circadian clock in cyanobacterium Synechococcus elongatus PCC7942” by Zhang <198
Multiregional profiling of the brain transmembrane proteome uncovers novel regulators of depression198
Editor’s note and erratum for the Research Article: “Unemployment and underemployment are causes of suicide”195
Erratum for the Research Article: “TREM2 inhibition triggers antitumor cell activity of myeloid cells in glioblastoma” by Sun et al .194
Targeting TRPC channels for control of arthritis-induced bone erosion193
Molybdate uptake interplay with ROS tolerance modulates bacterial pathogenesis191
Separation and recycling of hydrofluorocarbon refrigerant mixtures with fluoropolymer-coated hollow fiber membranes191
Artificial biomarker-based feedback-regulated personalized and precise thrombolysis with lower hemorrhagic risk190
Oral iron sulfide prevents acute alcohol intoxication by initiating the endogenous multienzymatic antioxidant defense system188
Real-space investigation of polarons in hematite Fe 2 O 3188
Long noncoding RNA DREAMer bridges the DREAM complex and E2f1 to regulate endoreplication in Drosophila188
Distributed interfacing by nanoscale photodiodes enables single-neuron light activation and sensory enhancement in 3D spinal explants187
Real-time antiproton annihilation vertexing with submicrometer resolution185
Autocatalytic assembly of a chimeric aminoacyl-RNA synthetase ribozyme184
Relations between absorption, emission, and excited state chemical potentials from nanocrystal 2D spectra184
Direct observation of multiband transport in magnonic Penrose quasicrystals via broadband and phase-resolved spectroscopy183
Targeting OXPHOS de novo purine synthesis as the nexus of FLT3 inhibitor–mediated synergistic antileukemic actions183
Compressing slippery surface-assembled amphiphiles for tunable haptic energy harvesters182
Sensory-motor circuit is a therapeutic target for dystonia musculorum mice, a model of hereditary sensory and autonomic neuropathy 6181
Saturn’s F ring is intermittently shepherded by Prometheus181
Observation of dynamic nuclear polarization echoes178
Multiplexed mapping of the interactome of GPCRs with receptor activity–modifying proteins177
CMOS-compatible electro-optical SRAM cavity device based on negative differential resistance176
Rise in broadly cross-reactive adaptive immunity against human β-coronaviruses in MERS-recovered patients during the COVID-19 pandemic176
Spinning and corkscrewing of oceanic macroplankton revealed through in situ imaging176
Signatures of speech and song: “Universal” links despite cultural diversity176
The cohesin stabilizer Sororin drives G 2 -M transition and spindle assembly in mammalian oocytes174
Chromobacterium biopesticide overcomes insecticide resistance in malaria vector mosquitoes174
Natural loss of function of ephrin-B3 shapes spinal flight circuitry in birds173
Divergent synthesis of complex withanolides enabled by a scalable route and late-stage functionalization172
Identification of the Wnt signal peptide that directs secretion on extracellular vesicles171
Deep and dynamic metabolic and structural imaging in living tissues171
Daily turnover of active giant virus infection during algal blooms revealed by single-cell transcriptomics170
Ancient genomes reveal Avar-Hungarian transformations in the 9th-10th centuries CE Carpathian Basin170
Ocean-induced melt volume directly paces ice loss from Pine Island Glacier164
Laws about bodily damage originate from shared intuitions about the value of body parts163
Cpeb1 remodels cell type–specific translational program to promote fear extinction163
A closed-loop catalytic nanoreactor system on a transistor163
Phosphorylation of XPD drives its mitotic role independently of its DNA repair and transcription functions163
Particle-armored liquid robots162
Cryo-EM visualization of DNA-PKcs structural intermediates in NHEJ162
Motion Hologram: Jointly optimized hologram generation and motion planning for photorealistic 3D displays via reinforcement learning159
Mismatched ligand density enables ordered assembly of mixed-dimensional, cross-species materials159
Structure and dynamics determine G protein coupling specificity at a class A GPCR159
Gender composition predicts gender bias: A meta-reanalysis of hiring discrimination audit experiments158
Time-resolving state-specific molecular dissociation with XUV broadband absorption spectroscopy158
Convergent consequences of parthenogenesis on stick insect genomes157
Spatially resolved single-cell atlas of ascidian endostyle provides insight into the origin of vertebrate pharyngeal organs156
If you rise, I fall: Equality is prevented by the misperception that it harms advantaged groups155
Rhombohedral-stacked bilayer transition metal dichalcogenides for high-performance atomically thin CMOS devices155
Enhanced NF-κB activation via HIV-1 Tat-TRAF6 cross-talk154
Multi-stimulus perception and visualization by an intelligent liquid metal-elastomer architecture154
Coxsackievirus infection induces direct pancreatic β cell killing but poor antiviral CD8 + T cell responses152
Rapid imaging of special nuclear materials for nuclear nonproliferation and terrorism prevention151
Dual activities of ACC synthase: Novel clues regarding the molecular evolution of ACS genes151
Real-time observation of non-equilibrium phonon-electron energy and angular momentum flow in laser-heated nickel151
Modulating environmental signals to reveal mechanisms and vulnerabilities of cancer persisters150
Dissecting the evolutionary role of the Hox gene proboscipedia in Drosophila mouthpart diversification by f150
Erratum for the Research Article: “SMAD4, activated by the TCR-triggered MEK/ERK signaling pathway, critically regulates CD8 + T cell cytotoxic function” by X. Liu 149
Engineering edgeless human skin with enhanced biomechanical properties149
A radio pulsar phase from SGR J1935+2154 provides clues to the magnetar FRB mechanism149
A conserved molecular template underlies color pattern diversity in estrildid finches149
Dephosphorylation and ion binding in prokaryotic calcium transport148
Ag-doped non–imperfection-enabled uniform memristive neuromorphic device based on van der Waals indium phosphorus sulfide148
High coherence and low cross-talk in a tileable 3D integrated superconducting circuit architecture148
Sparse ab initio x-ray transmission spectrotomography for nanoscopic compositional analysis of functional materials146
Attentional guidance through object associations in visual cortex146
Endogenous retroviruses mediate transcriptional rewiring in response to oncogenic signaling in colorectal cancer144
Inflammatory responses to acute carbon monoxide poisoning and the role of plasma gelsolin144
Tree-ring stable isotopes from the European Alps reveal long-term summer drying over the Holocene143
Direct observations of cross-scale wave-particle energy transfer in space plasmas143
Enhancer dynamics: Unraveling the mechanism of transcriptional bursting143
Depolarization block in olfactory sensory neurons expands the dimensionality of odor encoding142
Bound chiral magnonic polariton states for ideal microwave isolation141
Origin of potassic postcollisional volcanic rocks in young, shallow, blueschist-rich lithosphere141
Rac1 promotes kidney collecting duct repair by mechanically coupling cell morphology to mitotic entry140
Biological export production controls upper ocean calcium carbonate dissolution and CO 2 buffer capacity139
Liquid palladium for high-turnover carbon-carbon bond formation139
Mechanical tension mobilizes Lgr6 + epidermal stem cells to drive skin growth138
RGMa collapses the neuronal actin barrier against disease-implicated protein and exacerbates ALS138
Pancreatic tumor microenvironmental acidosis and hypoxia transform gold nanorods into cell-penetrant particles for potent radiosensitization138
Bone-inspired stress-gaining elastomer enabled by dynamic molecular locking138
Hibiscus bullseyes reveal mechanisms controlling petal pattern proportions that influence plant-pollinator interactions138
In vivo mapping of cellular resolution neuropathology in brain ischemia with diffusion MRI136
Focusing of in-plane hyperbolic polaritons in van der Waals crystals with tailored infrared nanoantennas136
Epidermal mutation accumulation in photodamaged skin is associated with skin cancer burden and can be targeted through ablative therapy135
Metasurface-based realization of photonic time crystals134
Cellular stiffness sensing through talin 1 in tissue mechanical homeostasis132
Monocytic MDSCs exhibit superior immune suppression via adenosine and depletion of adenosine improves efficacy of immunotherapy131
Inhibition of microbial deconjugation of micellar bile acids protects against intestinal permeability and liver injury130
Massively parallel quantification of phenotypic heterogeneity in single-cell drug responses130
Gene-rich UV sex chromosomes harbor conserved regulators of sexual development129
Inherent tendency of Synechococcus and heterotrophic bacteria for mutualism on long-term coexistence despite environmental interference129
Buffering of genetic dominance by allele-specific protein complex assembly129
VARP binds SNX27 to promote endosomal supercomplex formation on membranes129
Structural and computational design of a SARS-CoV-2 spike antigen with improved expression and immunogenicity129
Multicatalysis protocol enables direct and versatile enantioselective reductive transformations of secondary amides129
Transcriptional regulation of photoprotection in dark-to-light transition—More than just a matter of excess light energy129
Anthropogenic warming has ushered in an era of temperature-dominated droughts in the western United States128
Wnt signaling modulates mechanotransduction in the epidermis to drive hair follicle regeneration128
Biological self-protection inspired engineering of nanomaterials to construct a robust bio-nano system for environmental applications127
1.63-billion-year-old multicellular eukaryotes from the Chuanlinggou Formation in North China127
AMPK-dependent phosphorylation of MTFR1L regulates mitochondrial morphology127
Driving forces of Antarctic krill abundance127
Oxygen isotopes of anhydrous primary minerals show kinship between asteroid Ryugu and comet 81P/Wild2126
Stem cell mTOR signaling directs region-specific cell fate decisions during intestinal nutrient adaptation126
Volcanic CO 2 tracks the incubation period of basaltic paroxysms126
Spatial analysis of mitochondrial gene expression reveals dynamic translation hubs and remodeling in stress126
Abiotic molecular oxygen production—Ionic pathway from sulfur dioxide126
Quantum imaging of biological organisms through spatial and polarization entanglement125
Synthesis of defect-rich La 2 O 2 CO 3 supports for enhanced CO 2 125
De novo macrocyclic peptides for inhibiting, stabilizing, and probing the function of the retromer endosomal trafficking complex124
A printed luminescent flier inspired by plant seeds for eco-friendly physical sensing124
Significant loophole-free test of Kochen-Specker contextuality using two species of atomic ions124
Imaging local diffusion in microstructures using NV-based pulsed field gradient NMR123
High-throughput production of kilogram-scale nanofibers by Kármán vortex solution blow spinning123
Zika virus noncoding RNA cooperates with the viral protein NS5 to inhibit STAT1 phosphorylation and facilitate viral pathogenesis122
Comediation of voltage gating and ion charge in MXene membrane for controllable and selective monovalent cation separation122
Predicting master transcription factors from pan-cancer expression data122
Optimizing the timing of an end-of-outbreak declaration: Ebola virus disease in the Democratic Republic of the Congo122
LC3-associated endocytosis and the functions of Rubicon and ATG16L1122
Underwater metamaterial absorber with impedance-matched composite122
Spiral self-assembly of lamellar micelles into multi-shelled hollow nanospheres with unique chiral architecture121
An artificial intelligence enabled chemical synthesis robot for exploration and optimization of nanomaterials121
Looping-in complexation and ion partitioning in nonstoichiometric polyelectrolyte mixtures120
GPCR-mediated calcium and cAMP signaling determines psychosocial stress susceptibility and resiliency120
Light affects the prefrontal cortex via intrinsically photosensitive retinal ganglion cells120
Structure and electron transfer pathways of an electron-bifurcating NiFe-hydrogenase120
N -Heterocyclic carbene catalytic 1,2-boron migrative acylation accelerated by photocatalysis119
Ordered planar plating/stripping enables deep cycling zinc metal batteries119
Elevated type I interferon responses potentiate metabolic dysfunction, inflammation, and accelerated aging in mtDNA mutator mice119
Non-adapted bacterial infection suppresses plant reproduction118
The genomic landscape of familial glioma118
The synovial environment steers cartilage deterioration and regeneration118
Subcellular organization of viral particles during maturation of nucleus-forming jumbo phage118
Emergence and reconfiguration of modular structure for artificial neural networks during continual familiarity detection118
Diving into the vertical dimension of elasmobranch movement ecology118
Plasmid hypermutation using a targeted artificial DNA replisome118
Dynamic phase transitions dictate the size effect and activity of supported gold catalysts118
The potassium transporter TaNHX2 interacts with TaGAD1 to promote drought tolerance via modulating stomatal aperture in wheat118
GDF8 inhibition enhances musculoskeletal recovery and mitigates posttraumatic osteoarthritis following joint injury117
3D DNA origami pincers that multitask on giant unilamellar vesicles117
Mechanistic insights into the roles of the UFM1 E3 ligase complex in ufmylation and ribosome-associated protein quality control116
Sensing spin wave excitations by spin defects in few-layer-thick hexagonal boron nitride116
Phyto-inspired sustainable and high-performance fabric generators via moisture absorption-evaporation cycles116
Symmetry disruption commits vault particles to disassembly116
Conserved sites on the influenza H1 and H3 hemagglutinin recognized by human antibodies116
Inhalable Nanobody (PiN-21) prevents and treats SARS-CoV-2 infections in Syrian hamsters at ultra-low doses115
Quantum imaging of the reconfigurable VO 2 synaptic electronics for neuromorphic computing115
Rare earth elements from waste115
A computational mechanism of cue-stimulus integration for pain in the brain115
Palimpsest memories stored in memristive synapses115
Pd/Xu-Phos-catalyzed asymmetric elimination of fully substituted enol triflates into axially chiral trisubstituted allenes115
Maternal chemosignals enhance infant-adult brain-to-brain synchrony115
Articular fibrocartilage-targeted therapy by microtubule stabilization115
Early Middle Stone Age personal ornaments from Bizmoune Cave, Essaouira, Morocco115
Optical control of 4 f orbital state in rare-earth metals114
Increasing co-occurrence of fine particulate matter and ground-level ozone extremes in the western United States114
Overexpression of the scopoletin biosynthetic pathway enhances lignocellulosic biomass processing114
The molecular mechanism of sialic acid transport mediated by Sialin114
Rising dissolved organic carbon concentrations in coastal waters of northwestern Borneo related to tropical peatland conversion113
Cerebrospinal fluid flow extends to peripheral nerves further unifying the nervous system113
Hierarchical twinning governed by defective twin boundary in metallic materials113
A monolayer crystalline covalent network of polyoxometalate clusters113
Fungal-fungal cocultivation leads to widespread secondary metabolite alteration requiring the partial loss-of-function VeA1 protein112
A solid-to-solid metallic conversion electrochemistry toward 91% zinc utilization for sustainable aqueous batteries112
Dipeptidase-1 governs renal inflammation during ischemia reperfusion injury112
Modeling mechanical activation of macrophages during pulmonary fibrogenesis for targeted anti-fibrosis therapy112
Alcaligenes faecalis corrects aberrant matrix metalloproteinase expression to promote reepithelialization of diabetic wounds112
Role of hierarchy structure on the mechanical adaptation of self-healing hydrogels under cyclic stretching111
Blind identification of the spinal cord output in humans with high-density electrode arrays implanted in muscles111
Modularized microrobot with lock-and-detachable modules for targeted cell delivery in bile duct110
The super elongation complex drives transcriptional addiction in MYCN -amplified neuroblastoma110
An artificial sodium-selective subnanochannel110
Schrödinger’s red pixel by quasi-bound-states-in-the-continuum110
Locally controllable magnetic soft actuators with reprogrammable contraction-derived motions110
A biopolymer hydrogel electrostatically reinforced by amino-functionalized bioactive glass for accelerated bone regeneration110
Structural insights into the mechanism of human NPC1L1-mediated cholesterol uptake110
Tailoring sub-3.3 Å ultramicropores in advanced carbon molecular sieve membranes for blue hydrogen production110
Early IGF-1 receptor inhibition in mice mimics preterm human brain disorders and reveals a therapeutic target110
Soft robotic origami crawler110
Elder fish means more microplastics? Alaska pollock microplastic story in the Bering Sea110
Biodegradable electrospinning superhydrophilic nanofiber membranes for ultrafast oil-water separation109
Anthropogenic forcing has increased the risk of longer-traveling and slower-moving large contiguous heatwaves109
Regulation of PD-L1 through direct binding of cholesterol to CRAC motifs108
Distributed sensing along fibers for smart clothing108
Autophagy suppresses the formation of hepatocyte-derived cancer-initiating ductular progenitor cells in the liver107
Plakophilin-2 truncating variants impair cardiac contractility by disrupting sarcomere stability and organization107
Quantifying structural relationships of metal-binding sites suggests origins of biological electron transfer107
Exosome-mediated delivery of Cas9 ribonucleoprotein complexes for tissue-specific gene therapy of liver diseases107
Acetylcarnitine shuttling links mitochondrial metabolism to histone acetylation and lipogenesis106
Correlated x-ray fluorescence and ptychographic nano-tomography on Rembrandt’s The Night Watch reveals unknown lead “layer”106
Engineered IL-7 synergizes with IL-12 immunotherapy to prevent T cell exhaustion and promote memory without exacerbating toxicity106
The void formation behaviors in working solid-state Li metal batteries105
Uncertainties too large to predict tipping times of major Earth system components from historical data105
Structures of neurokinin 1 receptor in complex with G q and G s proteins reveal substance P binding mode and unique activation fea105
Shear shock waves mediate haptic holography via focused ultrasound105
A DNA circuit that records molecular events105
High-entropy materials for catalysis: A new frontier105
6mA-Sniper: Quantifying 6mA sites in eukaryotes at single-nucleotide resolution105
Structural and quantum chemical basis for OCP-mediated quenching of phycobilisomes104
On-demand modulating afterglow color of water-soluble polymers through phosphorescence FRET for multicolor security printing104
Valence electron concentration as key parameter to control the fracture resistance of refractory high-entropy carbides104
Activation of the NRF2 antioxidant program sensitizes tumors to G6PD inhibition104
Magnetic fields and relativistic electrons fill entire galaxy cluster104
Generative hypergraph clustering: From blockmodels to modularity104
The D614G mutation redirects SARS-CoV-2 spike to lysosomes and suppresses deleterious traits of the furin cleavage site insertion mutation103
Age-dependent acquisition of pathogenicity by SARS-CoV-2 Omicron BA.5103
Analysis of sloppiness in model simulations: Unveiling parameter uncertainty when mathematical models are fitted to data103
Evolutionary epigenomic analyses in mammalian early embryos reveal species-specific innovations and conserved principles of imprinting103
How genomic insights into the evolutionary history of clouded leopards inform their conservation103
Large-scale, robust mushroom-shaped nanochannel array membrane for ultrahigh osmotic energy conversion103
0.070764064788818