Science Advances

Article	Citations
Ultrafast tomograms in a flash	2526
Saturn’s F ring is intermittently shepherded by Prometheus	920
Developmentally programmed histone H3 expression regulates cellular plasticity at the parental-to-early embryo transition	481
Diamond-based microwave quantum amplifier	454
HfZrO-based synaptic resistor circuit for a Super-Turing intelligent system	390
Orbital angular momentum–driven multistate photomemory	383
Time-resolving state-specific molecular dissociation with XUV broadband absorption spectroscopy	375
Rhombohedral-stacked bilayer transition metal dichalcogenides for high-performance atomically thin CMOS devices	370
Pfs230 domain 12 is a potent malaria transmission–blocking vaccine candidate	358
Optimizing the timing of an end-of-outbreak declaration: Ebola virus disease in the Democratic Republic of the Congo	351
Discovery of an autoinhibited conformation in mesotrypsin reveals a strategy for selective serine protease inhibition	344
Spinning and corkscrewing of oceanic macroplankton revealed through in situ imaging	335
A molecular switch controls assembly of bacterial focal adhesions	326
Unmasking of the von Willebrand A-domain surface adhesin CglB at bacterial focal adhesions mediates myxobacterial gliding motility	324
Rac1 promotes kidney collecting duct repair by mechanically coupling cell morphology to mitotic entry	319
Cryo-EM visualization of DNA-PKcs structural intermediates in NHEJ	318
Non-adapted bacterial infection suppresses plant reproduction	311
HIV-1 manipulates CD96 on CD4 + T cells to subvert antiviral immunity	311
Gating of hair cell Ca 2+ channels governs the activity of cochlear neurons	295
Repeated climate-driven dispersal and speciation in peripheral populations of Pleistocene mastodons	295
Donor HLA-DQ genetic and functional divergence affect the control of BK polyoma virus infection after kidney transplantation	286
Artificial intelligence–enabled “inherited noninvasive intracellular recording” for prolonged monitoring of cardiac action potentials	282
Pathways to concealed gun carrying	282
GPCR-mediated calcium and cAMP signaling determines psychosocial stress susceptibility and resiliency	279
Targeting OXPHOS de novo purine synthesis as the nexus of FLT3 inhibitor–mediated synergistic antileukemic actions	270

Fluid dynamical pathways of airborne transmission while waiting in a line	268
Signatures of speech and song: “Universal” links despite cultural diversity	261
Identification of the Wnt signal peptide that directs secretion on extracellular vesicles	255
Characterizing many-body dynamics with projected ensembles on a superconducting quantum processor	255
Complementary corticostriatal circuits orchestrate action repetition and switching	254
Buffering of genetic dominance by allele-specific protein complex assembly	236
Cold exposure stimulates cross-tissue metabolic rewiring to fuel glucose-dependent thermogenesis in brown adipose tissue	234
Considering intentional stratospheric dehydration for climate benefits	232
Targeting transthyretin by one Cas9 variant with superfidelity and broad compatibility	226
Dynamic control of molecular transport MXene transistor membranes	226
Editor’s note and erratum for the Research Article: “Unemployment and underemployment are causes of suicide”	224
Erratum for the Research Article: “TREM2 inhibition triggers antitumor cell activity of myeloid cells in glioblastoma” by Sun et al .	224
Erratum for the Research Article: “Oscillation of type IV pili regulated by the circadian clock in cyanobacterium Synechococcus elongatus PCC7942” by Zha	223
Erratum for the Research Article: “SMAD4, activated by the TCR-triggered MEK/ERK signaling pathway, critically regulates CD8 + T cell cytotoxic funct	222
Epidermal mutation accumulation in photodamaged skin is associated with skin cancer burden and can be targeted through ablative therapy	221
Healing of ischemic injury in the retina	221
Mismatched ligand density enables ordered assembly of mixed-dimensional, cross-species materials	221
Optical control of 4 f orbital state in rare-earth metals	221
Emergence and reconfiguration of modular structure for artificial neural networks during continual familiarity detection	220
Upward propagation of gigantic jets revealed by 3D radio and optical mapping	219
A computational mechanism of cue-stimulus integration for pain in the brain	212
Overexpression of the scopoletin biosynthetic pathway enhances lignocellulosic biomass processing	211
Engineering is pregnant with possibilities	211
Correlated x-ray fluorescence and ptychographic nano-tomography on Rembrandt’s The Night Watch reveals unknown lead “layer”	210
The Plasmodium falciparum PPCS is a unique heteromeric complex with prokaryote-like activity and is a target of pantothenate analogs	205
Atomic-scale physical unclonable functions in solids	203
Transcriptional regulation of photoprotection in dark-to-light transition—More than just a matter of excess light energy	201
Rise in broadly cross-reactive adaptive immunity against human β-coronaviruses in MERS-recovered patients during the COVID-19 pandemic	200
Efficient launching of shear phonons in photostrictive halide perovskites	200
Removal of trace gases can both increase and decrease cloud droplet formation	200
A plant NLR receptor activates auxin signaling through Aux/IAAs-ARF19 and YUC8-TIR1/AFBs to promote callose-mediated antiviral defense	196
Bacterial communities co-develop with respiratory immunity early in life, linking dysbiosis to systemic monocyte signature and wheezing	195
Notch signaling blockade links transcriptome heterogeneity in quiescent neural stem cells with reactivation routes and potential	194
X-ray phase measurements by time-energy correlated photon pairs	192
Endogenous retroviruses mediate transcriptional rewiring in response to oncogenic signaling in colorectal cancer	192
Miniature color camera via flat hybrid meta-optics	191
6mA-Sniper: Quantifying 6mA sites in eukaryotes at single-nucleotide resolution	190
Separation and recycling of hydrofluorocarbon refrigerant mixtures with fluoropolymer-coated hollow fiber membranes	188
Hidden white and black feather layers enhance plumage coloration in tanagers and other songbirds	187
Mechanistic insights into the roles of the UFM1 E3 ligase complex in ufmylation and ribosome-associated protein quality control	186
Targeting PD-1 + T cells with chimeric antigen receptors to reduce the HIV reservoir	186
Pd/Xu-Phos-catalyzed asymmetric elimination of fully substituted enol triflates into axially chiral trisubstituted allenes	186
Transferring strongly reducing electrons to bidentate-adsorbed CO 2 for efficient and selective formate photosynthesis	185
VARP binds SNX27 to promote endosomal supercomplex formation on membranes	182
Divergent synthesis of complex withanolides enabled by a scalable route and late-stage functionalization	181
All eukaryotic SMC proteins induce a twist of −0.6 at each DNA loop extrusion step	179
Shear shock waves mediate haptic holography via focused ultrasound	179
Artificial biomarker-based feedback-regulated personalized and precise thrombolysis with lower hemorrhagic risk	179
Metabolic reprogramming in Fanconi anemia: Evidence of compromised glucose oxidation, enhanced ketogenesis, and metabolic inflexibility	176
Genome wide nucleosome landscape shapes 3D chromatin organization	175

A DNA circuit that records molecular events	174
CMOS-compatible electro-optical SRAM cavity device based on negative differential resistance	173
Pan-cortical cellular imaging in freely behaving mice using a miniaturized micro-camera array microscope (mini-MCAM)	173
Miniature battery-free epidural cortical stimulators	172
Injectable shear-thinning hydrogels promote oligodendrocyte progenitor cell survival and remyelination in the central nervous system	172
Multiplexed mapping of the interactome of GPCRs with receptor activity–modifying proteins	171
An evolutionary conserved neural mechanism for interpersonal coordination in primates	171
Unpacking the growth of global agricultural greenhouse gas emissions	169
Compressing slippery surface-assembled amphiphiles for tunable haptic energy harvesters	169
Navigating high-dimensional processing parameters in organic photovoltaics via a multitier machine learning framework	168
Uncovering the rapidly evolving orbits of the dynamic TOI-201 system	167
Clusters of lineage-specific genes are anchored by ZNF274 in repressive perinucleolar compartments	167
Smart ultra-long-lasting sequentially triggerable and artfully implantable nozzle system for on-demand drug delivery for chronotherapy	166
RIPK1 inhibition reduces biliary injury and fibrosis in primary sclerosing cholangitis	165
Direct observations of cross-scale wave-particle energy transfer in space plasmas	165
Bone-inspired stress-gaining elastomer enabled by dynamic molecular locking	165
Distributed sensing along fibers for smart clothing	164
Electrostatic nano-mask patterned 180° domain walls in a ferroelectric film	164
Stretchable complementary integrated electronics based on elastic dual-type transistors	164
Seeing through arthropod eyes: An AI-assisted, biomimetic approach for high-resolution, multi-task imaging	160
Alcaligenes faecalis corrects aberrant matrix metalloproteinase expression to promote reepithelialization of diabetic wounds	160
GDF8 inhibition enhances musculoskeletal recovery and mitigates posttraumatic osteoarthritis following joint injury	160
Ancient genomes reveal Avar-Hungarian transformations in the 9th-10th centuries CE Carpathian Basin	160
Sensory-motor circuit is a therapeutic target for dystonia musculorum mice, a model of hereditary sensory and autonomic neuropathy 6	159
Munc13-1 couples DAG and Ca 2+ signaling to dynamic vesicle priming, synaptic short-term plasticity, and posttetanic potentiation	159
Prebunking and credible source corrections increase election credibility: Evidence from the US and Brazil	159
A solid-to-solid metallic conversion electrochemistry toward 91% zinc utilization for sustainable aqueous batteries	158
Invariable resistance of conductive nanocomposite over 30% strain	157
Liquid palladium for high-turnover carbon-carbon bond formation	156
Sensing spin wave excitations by spin defects in few-layer-thick hexagonal boron nitride	155
Ideological bias in the production of research findings	154
Deep and dynamic metabolic and structural imaging in living tissues	154
The super elongation complex drives transcriptional addiction in MYCN -amplified neuroblastoma	154
Plasma-enhanced electronic textiles for energy harvesting	153
Zika virus noncoding RNA cooperates with the viral protein NS5 to inhibit STAT1 phosphorylation and facilitate viral pathogenesis	153
MiniXL: An open-source, large field-of-view epifluorescence miniscope enabling single-cell resolution and multi-region imaging in mice	152
In vivo membrane engineering traps Gd-based MRI contrast agents for detecting microhepatocellular carcinoma	151
Oral iron sulfide prevents acute alcohol intoxication by initiating the endogenous multienzymatic antioxidant defense system	150
2D material exciton-polariton transport on 2D photonic crystals	150
Memristive floating-point Fourier neural operator network for efficient scientific modeling	149
Disaggregated machine learning via in-physics computing at radio frequency	149
Molybdate uptake interplay with ROS tolerance modulates bacterial pathogenesis	149
Pancreatic tumor microenvironmental acidosis and hypoxia transform gold nanorods into cell-penetrant particles for potent radiosensitization	149
Global health risks lurking in livestock resistome	149
Observation of dynamic nuclear polarization echoes	148
Targeting TRPC channels for control of arthritis-induced bone erosion	146
Age-dependent acquisition of pathogenicity by SARS-CoV-2 Omicron BA.5	146
Erratum for the Research Article “A multi-agentic framework for real-time, autonomous freeform metasurface design” by R. Lupoiu et al .	145
Investigating charge accumulation mechanisms in organic materials via slow transient emission spectroscopy	144
Kir7.1 is the physiological target for hormones and steroids that regulate uteroplacental function	144
Dephosphorylation and ion binding in prokaryotic calcium transport	143
Autocatalytic assembly of a chimeric aminoacyl-RNA synthetase ribozyme	143
Optical and electrical probing of plasmonic metal-molecule interactions	142
Chromobacterium biopesticide overcomes insecticide resistance in malaria vector mosquitoes	141
Small effect of partial melt on electrical anomalies in the asthenosphere	141
Designing a DNA synchronizer for compact single-rail DNA logic circuits	141
Monocytic MDSCs exhibit superior immune suppression via adenosine and depletion of adenosine improves efficacy of immunotherapy	140
Decoding paradoxical BOLD responses to transcranial ultrasound stimulation with concurrent optoacoustic magnetic resonance imaging	139
Laws about bodily damage originate from shared intuitions about the value of body parts	139
Structural and quantum chemical basis for OCP-mediated quenching of phycobilisomes	139
AMPK-dependent phosphorylation of MTFR1L regulates mitochondrial morphology	138
Early IGF-1 receptor inhibition in mice mimics preterm human brain disorders and reveals a therapeutic target	137
Low-waste, single-step, sustainable extraction of critical metals from deep-sea polymetallic nodules	137
How genomic insights into the evolutionary history of clouded leopards inform their conservation	136
Real-time observation of non-equilibrium phonon-electron energy and angular momentum flow in laser-heated nickel	136
Cpeb1 remodels cell type–specific translational program to promote fear extinction	136
The synovial environment steers cartilage deterioration and regeneration	136
Comediation of voltage gating and ion charge in MXene membrane for controllable and selective monovalent cation separation	136
The D614G mutation redirects SARS-CoV-2 spike to lysosomes and suppresses deleterious traits of the furin cleavage site insertion mutation	136
Cerebrospinal fluid flow extends to peripheral nerves further unifying the nervous system	135
Hibiscus bullseyes reveal mechanisms controlling petal pattern proportions that influence plant-pollinator interactions	135
Quantum imaging of the reconfigurable VO 2 synaptic electronics for neuromorphic computing	135
Microsecond dynamics control the HIV-1 Envelope conformation	134
A poxvirus model reveals general correlates of antigen presentation and immunogenicity for viral CD8 + T cell epitopes	134
CysMP reveals metal ion–specific metalloproteomes and copper-regulated PGK1 activity in glycolysis	134
Autologous human iPSC–derived alveolus-on-chip reveals early pathological events of Mycobacterium tuberculosis infection	133
Engineered IL-7 synergizes with IL-12 immunotherapy to prevent T cell exhaustion and promote memory without exacerbating toxicity	133
Depolarization block in olfactory sensory neurons expands the dimensionality of odor encoding	133
Magnetic fields and relativistic electrons fill entire galaxy cluster	132
Flash annealing–engineered wafer-scale relaxor antiferroelectrics for enhanced energy storage performance	132

Synergistic antioxidant and gene supplementation for high-efficacy retinitis pigmentosa therapy	132
Biological export production controls upper ocean calcium carbonate dissolution and CO 2 buffer capacity	132
Beyond seizure control: Identifying deficits in cognitive networks in absence epilepsy	132
Distinct armchair and zigzag charge transport through single polycyclic aromatics	131
DNA repair during nonreductional meiosis in the asexual rotifer Adineta vaga	131
27-Hydroxycholesterol acts on estrogen receptor α expressed by POMC neurons in the arcuate nucleus to modulate feeding behavior	131
Phosphorylation of XPD drives its mitotic role independently of its DNA repair and transcription functions	131
The genomic landscape of familial glioma	131
Ultrastrong Staphylococcus aureus adhesion to human skin: Calcium as a key regulator of noncovalent interactions	131
Allospecific splenic Tr1 cells drive effector T cell exhaustion through up-regulated Areg-EGFR signaling to promote transplant tolerance	131
Attentional guidance through object associations in visual cortex	131
Imaging local diffusion in microstructures using NV-based pulsed field gradient NMR	130
Phylogenetic tracing of midbrain-specific regulatory sequences suggests single origin of eubilaterian brains	130
Enhanced Rap1 small GTPase activity in the ventral hippocampus drives stress-induced anxiety	130
A conserved molecular template underlies color pattern diversity in estrildid finches	130
Oxygen isotopes of anhydrous primary minerals show kinship between asteroid Ryugu and comet 81P/Wild2	129
In vivo mapping of cellular resolution neuropathology in brain ischemia with diffusion MRI	129
Structural and computational design of a SARS-CoV-2 spike antigen with improved expression and immunogenicity	128
Enhancer dynamics: Unraveling the mechanism of transcriptional bursting	128
Real-space visualization of order-disorder transition in BaTiO 3	128
Structure and dynamics determine G protein coupling specificity at a class A GPCR	127
An annually resolved 5700-year storm archive reveals drivers of Caribbean cyclone frequency	127
Palimpsest memories stored in memristive synapses	126
A two-stage mantle plume-sagduction origin of Archean continental crust revealed by water and oxygen isotopes of TTGs	126
Broadband photodetection of intense lasers via exciton-enhanced high-order multiphoton-absorption optoelectronics in 2D hybrid perovskite	125
Abiotic molecular oxygen production—Ionic pathway from sulfur dioxide	125
Attosecond spectroscopy reveals spontaneous symmetry breaking in molecular photoionization	125
Motion Hologram: Jointly optimized hologram generation and motion planning for photorealistic 3D displays via reinforcement learning	124
Modularized microrobot with lock-and-detachable modules for targeted cell delivery in bile duct	124
Episodic reef growth in the Last Interglacial driven by competing influence of polar ice sheets to sea level rise	123
Multi-stimulus perception and visualization by an intelligent liquid metal-elastomer architecture	123
Analysis of sloppiness in model simulations: Unveiling parameter uncertainty when mathematical models are fitted to data	123
Size-dependent temporal decoupling of morphogenesis and transcriptional programs in pseudoembryos	122
Development of xanthone derivatives as effective broad-spectrum antimicrobials: Disrupting cell wall and inhibiting DNA synthesis	122
1.63-billion-year-old multicellular eukaryotes from the Chuanlinggou Formation in North China	122
Dissecting abstract, modality-specific and experience-dependent coding of affect in the human brain	122
Neuromuscular embodiment of feedback control elements in Drosophila flight	121
Scalable generalized meta-spanners enabling parallel multitasking optical manipulation	121
Distributed interfacing by nanoscale photodiodes enables single-neuron light activation and sensory enhancement in 3D spinal explants	121
Articular fibrocartilage-targeted therapy by microtubule stabilization	120
Inflammatory responses to acute carbon monoxide poisoning and the role of plasma gelsolin	120
Real-space investigation of polarons in hematite Fe 2 O 3	120
Elder fish means more microplastics? Alaska pollock microplastic story in the Bering Sea	120
Elucidating the characteristics and clonal evolutionary trajectory of influenza neuraminidase broadly reactive B cell	120
Wnt signaling modulates mechanotransduction in the epidermis to drive hair follicle regeneration	120
DNA damage response pathway regulates Nrf2 in response to oxidative stress	119
Role of HAUS7 as a DOCK3 binding partner in facilitating axon regeneration	118
Driving forces of Antarctic krill abundance	118
RGMa collapses the neuronal actin barrier against disease-implicated protein and exacerbates ALS	117
Diurnal urban rainfall anomalies across different landscapes	117
Enhanced NF-κB activation via HIV-1 Tat-TRAF6 cross-talk	117
Diversification of the ruminant skull along an evolutionary line of least resistance	117
A printed luminescent flier inspired by plant seeds for eco-friendly physical sensing	117
The potassium transporter TaNHX2 interacts with TaGAD1 to promote drought tolerance via modulating stomatal aperture in wheat	117
Phyto-inspired sustainable and high-performance fabric generators via moisture absorption-evaporation cycles	117
Uncertainties too large to predict tipping times of major Earth system components from historical data	117
Inhibition of microbial deconjugation of micellar bile acids protects against intestinal permeability and liver injury	116
A closed-loop catalytic nanoreactor system on a transistor	116
Proteome-wide computational analyses reveal links between protein condensate formation and RNA biology	116
Real-time antiproton annihilation vertexing with submicrometer resolution	116
An artificial sodium-selective subnanochannel	115
Anthropogenic forcing has increased the risk of longer-traveling and slower-moving large contiguous heatwaves	115
Conserved sites on the influenza H1 and H3 hemagglutinin recognized by human antibodies	115
Blind identification of the spinal cord output in humans with high-density electrode arrays implanted in muscles	114
Daily turnover of active giant virus infection during algal blooms revealed by single-cell transcriptomics	114
The extinct shark Otodus megalodon was a transoceanic superpredator: Inferences from 3D modeling	114
Multiplexed CRISPR-Cas9 mutagenesis of rice PSBS1 noncoding sequences for transgene-free overexpression	114
Water doping sodium battery electrolyte controls nanostructure, interactions, and electrochemical properties	114
Ordered planar plating/stripping enables deep cycling zinc metal batteries	114
Correlated quantum machines beyond the standard second law	114
Low-dose metformin requires brain Rap1 for its antidiabetic action	113
Modeling mechanical activation of macrophages during pulmonary fibrogenesis for targeted anti-fibrosis therapy	113
Bound chiral magnonic polariton states for ideal microwave isolation	112
Long noncoding RNA DREAMer bridges the DREAM complex and E2f1 to regulate endoreplication in Drosophila	112
Light affects the prefrontal cortex via intrinsically photosensitive retinal ganglion cells	112
Spatially entangled photon pairs from lithium niobate nonlocal metasurfaces	112
Exosome-mediated delivery of Cas9 ribonucleoprotein complexes for tissue-specific gene therapy of liver diseases	112
Valence electron concentration as key parameter to control the fracture resistance of refractory high-entropy carbides	112
Stem cell mTOR signaling directs region-specific cell fate decisions during intestinal nutrient adaptation	111
Predicting three-component reaction outcomes from ~40,000 miniaturized reactant combinations	111
A monolayer crystalline covalent network of polyoxometalate clusters	111
Particle-armored liquid robots	111
Gender composition predicts gender bias: A meta-reanalysis of hiring discrimination audit experiments	110
Anthropogenic warming has ushered in an era of temperature-dominated droughts in the western United States	110
Inherent tendency of Synechococcus and heterotrophic bacteria for mutualism on long-term coexistence despite environmental interference	110
A universal oxygen scavenger for oxidase-based biosensors	109
Chaperone-mediated heterotypic phase separation regulates liquid-to-solid phase transitions of tau into amyloid fibrils	109
Dynamic phase transitions dictate the size effect and activity of supported gold catalysts	109
Cellular stiffness sensing through talin 1 in tissue mechanical homeostasis	109
Metasurface-based realization of photonic time crystals	109
Quantum imaging of biological organisms through spatial and polarization entanglement	108
The molecular mechanism of sialic acid transport mediated by Sialin	108
Tree-ring stable isotopes from the European Alps reveal long-term summer drying over the Holocene	108
A radio pulsar phase from SGR J1935+2154 provides clues to the magnetar FRB mechanism	107
Engineering edgeless human skin with enhanced biomechanical properties	107