ACS Infectious Diseases

Article	Citations
Recent Innovations in Bacterial Infection Detection and Treatment	136
Proteolytic Activation of SARS-CoV-2 Spike at the S1/S2 Boundary: Potential Role of Proteases beyond Furin	129
Comparative Multiplexed Interactomics of SARS-CoV-2 and Homologous Coronavirus Nonstructural Proteins Identifies Unique and Shared Host-Cell Dependencies	90
Synthetic Antimicrobial Polymers in Combination Therapy: Tackling Antibiotic Resistance	82
Small-Molecule Inhibitors of the Coronavirus Spike: ACE2 Protein–Protein Interaction as Blockers of Viral Attachment and Entry for SARS-CoV-2	81
Boceprevir, Calpain Inhibitors II and XII, and GC-376 Have Broad-Spectrum Antiviral Activity against Coronaviruses	74
Challenges for Targeting SARS-CoV-2 Proteases as a Therapeutic Strategy for COVID-19	70
Human Cathelicidin Inhibits SARS-CoV-2 Infection: Killing Two Birds with One Stone	67
The Structure-Based Design of SARS-CoV-2 nsp14 Methyltransferase Ligands Yields Nanomolar Inhibitors	64
Prospecting Human Milk Oligosaccharides as a Defense Against Viral Infections	64
Exogenous Nitric Oxide Improves Antibiotic Susceptibility in Resistant Bacteria	61
Recognition of Divergent Viral Substrates by the SARS-CoV-2 Main Protease	60
The SARS-CoV-2 Cytopathic Effect Is Blocked by Lysosome Alkalizing Small Molecules	60
Two Years into the COVID-19 Pandemic: Lessons Learned	59
Structure–Activity Relationship Studies of Acetazolamide-Based Carbonic Anhydrase Inhibitors with Activity against Neisseria gonorrhoeae	56
Reproducible Breath Metabolite Changes in Children with SARS-CoV-2 Infection	52
Emerging Vaccine-Breakthrough SARS-CoV-2 Variants	52
Mucin-Degrading Microbes Release Monosaccharides That Chemoattract Clostridioides difficile and Facilitate Colonization of the Human Intestinal Mucus Layer	51
Prioritization of Molecular Targets for Antimalarial Drug Discovery	50
A Glance at Antimicrobial Strategies to Prevent Catheter-Associated Medical Infections	48
Self-Assembly of Antimicrobial Peptoids Impacts Their Biological Effects on ESKAPE Bacterial Pathogens	47
Synergy by Perturbing the Gram-Negative Outer Membrane: Opening the Door for Gram-Positive Specific Antibiotics	45
Plasmodium Kinases as Potential Drug Targets for Malaria: Challenges and Opportunities	44
From Antibacterial to Antibiofilm Targeting: An Emerging Paradigm Shift in the Development of Quaternary Ammonium Compounds (QACs)	43
An Updated View of the Trypanosoma cruzi Life Cycle: Intervention Points for an Effective Treatment	42

Therapeutic Potential of Nitazoxanide: An Appropriate Choice for Repurposing versus SARS-CoV-2?	42
Synergistic Effects of Phage–Antibiotic Combinations against Citrobacter amalonaticus	42
Gut Microbiota and Gynecological Cancers: A Summary of Pathogenetic Mechanisms and Future Directions	40
Immunogenicity and Protective Efficacy of a Highly Thermotolerant, Trimeric SARS-CoV-2 Receptor Binding Domain Derivative	37
Heterologous Protein Expression Favors the Formation of Protein Aggregates in Persister and Viable but Nonculturable Bacteria	37
Nanomaterials: The New Antimicrobial Magic Bullet	37
HBsAg, Subviral Particles, and Their Clearance in Establishing a Functional Cure of Chronic Hepatitis B Virus Infection	37
Detection, Mapping, and Proteotyping of SARS-CoV-2 Coronavirus with High Resolution Mass Spectrometry	37
Structure and Mutations of SARS-CoV-2 Spike Protein: A Focused Overview	36
Inhibitors of L-Type Calcium Channels Show Therapeutic Potential for Treating SARS-CoV-2 Infections by Preventing Virus Entry and Spread	34
Peroxide Antimalarial Drugs Target Redox Homeostasis in Plasmodium falciparum Infected Red Blood Cells	34
Antibody Affinity Governs the Inhibition of SARS-CoV-2 Spike/ACE2 Binding in Patient Serum	33
Recent Advances in the Development of Semisynthetic Glycopeptide Antibiotics: 2014–2022	32
Quinoline and Quinazoline Derivatives Inhibit Viral RNA Synthesis by SARS-CoV-2 RdRp	31
Synthesis and Biological Activities of Oxazolidinone Pleuromutilin Derivatives as a Potent Anti-MRSA Agent	31
High-Throughput Screening of an FDA-Approved Drug Library Identifies Inhibitors against Arenaviruses and SARS-CoV-2	30
Antibiotic Potentiation in Multidrug-Resistant Gram-Negative Pathogenic Bacteria by a Synthetic Peptidomimetic	30
To Push or To Pull? In a Post-COVID World, Supporting and Incentivizing Antimicrobial Drug Development Must Become a Governmental Priority	29
Short and Robust Anti-Infective Lipopeptides Engineered Based on the Minimal Antimicrobial Peptide KR12 of Human LL-37	29
Binding Studies Reveal Phospholipid Specificity and Its Role in the Calcium-Dependent Mechanism of Action of Daptomycin	29
Compound Uptake into E. coli Can Be Facilitated by N-Alkyl Guanidiniums and Pyridiniums	27
Emerging Roles of Glycopeptide Antibiotics: Moving beyond Gram-Positive Bacteria	27
A Microbe-Derived Efflux Pump Inhibitor of the Resistance-Nodulation-Cell Division Protein Restores Antibiotic Susceptibility in Escherichia coli and Pseudomonas aeruginosa	27
New Antimicrobial Peptides with Repeating Unit against Multidrug-Resistant Bacteria	26
Development of Advanced Chimeric Endolysin to Control Multidrug-Resistant Staphylococcus aureus through Domain Shuffling	26
CRISPR-Cas-Based Antimicrobials: Design, Challenges, and Bacterial Mechanisms of Resistance	26
Altered Gut Microbiome under Antiretroviral Therapy: Impact of Efavirenz and Zidovudine	26
Development in the Concept of Bacterial Polysaccharide Repeating Unit-Based Antibacterial Conjugate Vaccines	26
Antiviral Activity of 7-Substituted 7-Deazapurine Ribonucleosides, Monophosphate Prodrugs, and Triphoshates against Emerging RNA Viruses	25
Imaging of Actively Proliferating Bacterial Infections by Targeting the Bacterial Metabolic Footprint with d-[5-11C]-Glutamine	25
Membrane-Permeable Antibacterial Enzyme against Multidrug-Resistant Acinetobacter baumannii	25
Synthesis of Fusidic Acid Derivatives Yields a Potent Antibiotic with an Improved Resistance Profile	25
Recent Insights into Emerging Coronavirus: SARS-CoV-2	25
A Highly Potent SARS-CoV-2 Blocking Lectin Protein	25
Protective Liquid Crystal Nanoparticles for Targeted Delivery of PslG: A Biofilm Dispersing Enzyme	25
Design and Evaluation of New Quinazolin-4(3H)-one Derived PqsR Antagonists as Quorum Sensing Quenchers in Pseudomonas aeruginosa	24
Combining Colistin and Fluconazole Synergistically Increases Fungal Membrane Permeability and Antifungal Cidality	24
Overcoming Planktonic and Intracellular Staphylococcus aureus-Associated Infection with a Cell-Penetrating Peptide-Conjugated Antimicrobial Peptide	24
Benzimidazole Derivatives Are Potent against Multiple Life Cycle Stages of Plasmodium falciparum Malaria Parasites	23
Screening a Library of FDA-Approved and Bioactive Compounds for Antiviral Activity against SARS-CoV-2	23
Antibiotic Therapy and the Gut Microbiome: Investigating the Effect of Delivery Route on Gut Pathogens	23
Cationic Antimicrobial Peptides Are Leading the Way to Combat Oropathogenic Infections	23
A Marine Antibiotic Kills Multidrug-Resistant Bacteria without Detectable High-Level Resistance	23
Small Molecule Inhibitors of the Bacterioferritin (BfrB)–Ferredoxin (Bfd) Complex Kill Biofilm-Embedded Pseudomonas aeruginosa Cells	22
Inhibition of Human Coronaviruses by Antimalarial Peroxides	22
Clinically Relevant Bacterial Outer Membrane Models for Antibiotic Screening Applications	22
Quaternary Phosphonium Compounds: An Examination of Non-Nitrogenous Cationic Amphiphiles That Evade Disinfectant Resistance	22
Modeling Enteropathy or Diarrhea with the Top Bacterial and Protozoal Pathogens: Differential Determinants of Outcomes	22
Ag@ZnO Nanoparticles Induce Antimicrobial Peptides and Promote Migration and Antibacterial Activity of Keratinocytes	22
Diclazuril Inhibits Biofilm Formation and Hemolysis of Staphylococcus aureus	22

Aptamers for Viral Detection and Inhibition	22
Ceftazidime–Avibactam Resistance Mutations V240G, D179Y, and D179Y/T243M in KPC-3 β-Lactamase Do Not Alter Cefpodoxime–ETX1317 Susceptibility	21
Analysis of Antimicrobial and Antibiofilm Activity of Human Milk Lactoferrin Compared to Bovine Lactoferrin against Multidrug Resistant and Susceptible Acinetobacter baumannii Clinical Isolates	21
A Machine Learning Strategy for Drug Discovery Identifies Anti-Schistosomal Small Molecules	21
Structural Basis of Metallo-β-lactamase Inhibition byN-Sulfamoylpyrrole-2-carboxylates	21
Impact of Glycan Linkage to Staphylococcus aureus Wall Teichoic Acid on Langerin Recognition and Langerhans Cell Activation	21
The SARS-CoV-2 SSHHPS Recognized by the Papain-like Protease	21
Recombinant Human Secretory IgA Induces Salmonella Typhimurium Agglutination and Limits Bacterial Invasion into Gut-Associated Lymphoid Tissues	20
SaccuFlow: A High-Throughput Analysis Platform to Investigate Bacterial Cell Wall Interactions	20
Investigating β-Lactam Drug Targets in Mycobacterium tuberculosis Using Chemical Probes	20
Selective Permeabilization of Gram-Negative Bacterial Membranes Using Multivalent Peptide Constructs for Antibiotic Sensitization	20
Exploitation of a Klebsiella Bacteriophage Receptor-Binding Protein as a Superior Biorecognition Molecule	20
Mechanistic Duality of Bacterial Efflux Substrates and Inhibitors: Example of Simple Substituted Cinnamoyl and Naphthyl Amides	20
Mechanistic Basis of OXA-48-like β-Lactamases’ Hydrolysis of Carbapenems	20
Expanding Bromodomain Targeting into Neglected Parasitic Diseases	20
Exotoxin-Targeted Drug Modalities as Antibiotic Alternatives	19
Pyochelin Biosynthetic Metabolites Bind Iron and Promote Growth in Pseudomonads Demonstrating Siderophore-like Activity	19
The Pandemic Response Box─Accelerating Drug Discovery Efforts after Disease Outbreaks	19
Intrinsic Antimicrobial Peptide Facilitates a New Broad-Spectrum Lysin LysP53 to Kill Acinetobacter baumannii In Vitro and in a Mouse Burn Infection Model	19
Therapeutic and Prophylactic Effect of the Experimental Bacteriophage Treatment to Control Diarrhea Caused by E. coli in Newborn Calves	19
Recent Advances in the Evaluation of Antimicrobial Materials for Resolution of Orthopedic Implant-Associated Infections In Vivo	19
Antileishmanial Chemotherapy through Clemastine Fumarate Mediated Inhibition of the Leishmania Inositol Phosphorylceramide Synthase	18
Vancomyxins: Vancomycin-Polymyxin Nonapeptide Conjugates That Retain Anti-Gram-Positive Activity with Enhanced Potency against Gram-Negative Strains	18
Development of Antibiotics That Dysregulate the Neisserial ClpP Protease	18
Feleucin-K3 Analogue with an α-(4-Pentenyl)-Ala Substitution at the Key Site Has More Potent Antimicrobial and Antibiofilm Activities in Vitro and in Vivo	18
Investigational Studies on a Hit Compound Cyclopropane–Carboxylic Acid Derivative Targeting O-Acetylserine Sulfhydrylase as a Colistin Adjuvant	18
Toolkit of Approaches To Support Target-Focused Drug Discovery for Plasmodium falciparum Lysyl tRNA Synthetase	18
Plasmodium falciparum Acetyl-CoA Synthetase Is Essential for Parasite Intraerythrocytic Development and Chromatin Modification	18
Sustained Release of a Streptococcus pneumoniae Endolysin from Liposomes for Potential Otitis Media Treatment	18
Design Guidelines for Cationic Pillar[n]arenes that Prevent Biofilm Formation by Gram-Positive Pathogens	18
Effects of Structurally Different HDAC Inhibitors against Trypanosoma cruzi, Leishmania, and Schistosoma mansoni	18
PfMFR3: A Multidrug-Resistant Modulator in Plasmodium falciparum	18
Antiviral Potential of the Antimicrobial Drug Atovaquone against SARS-CoV-2 and Emerging Variants of Concern	18
Conjugation to Enterobactin and Salmochelin S4 Enhances the Antimicrobial Activity and Selectivity of β-Lactam Antibiotics against Nontyphoidal Salmonella	18
Type II Antitoxin HigA Is a Key Virulence Regulator in Pseudomonas aeruginosa	18
Synthetic Mimics of Native Siderophores Disrupt Iron Trafficking in Acinetobacter baumannii	17
Azanitrile Inhibitors of the SmCB1 Protease Target Are Lethal to Schistosoma mansoni: Structural and Mechanistic Insights into Chemotype Reactivity	17
Early Returns on Small Molecule Therapeutics for SARS-CoV-2	17
MicroRNA-18b-5p Downregulation Favors Mycobacterium tuberculosis Clearance in Macrophages via HIF-1α by Promoting an Inflammatory Response	17
Virulence and Adhesion of the Treponema pallidum Nichols Strain Simultaneously Decrease in a Continuous-Infection New Zealand White Rabbit Model	17
Metabolic Glycan Labeling-Based Screen to Identify Bacterial Glycosylation Genes	17
Atypically Modified Carbapenem Antibiotics Display Improved Antimycobacterial Activity in the Absence of β-Lactamase Inhibitors	17
Antibacterial Photodynamic Therapy in the Near-Infrared Region with a Targeting Antimicrobial Peptide Connected to a π-Extended Porphyrin	17
Intrinsically Disordered Proteins: Perspective on COVID-19 Infection and Drug Discovery	17
Preclinical Development of Pentamidine Analogs Identifies a Potent and Nontoxic Antibiotic Adjuvant	17
Repurposing Nonantifungal Approved Drugs for Synergistic Targeting of Fungal Pathogens	17
Group B Streptococcus cpsE Is Required for Serotype V Capsule Production and Aids in Biofilm Formation and Ascending Infection of the Reproductive Tract during Pregnancy	16
Essential Bromodomain TcBDF2 as a Drug Target against Chagas Disease	16
Druggable Hot Spots in the Schistosomiasis Cathepsin B1 Target Identified by Functional and Binding Mode Analysis of Potent Vinyl Sulfone Inhibitors	16
Pyronaridine Protects against SARS-CoV-2 Infection in Mouse	16
Spatially Targeted Proteomics of the Host–Pathogen Interface during Staphylococcal Abscess Formation	16
2-Mercaptomethyl Thiazolidines (MMTZs) Inhibit All Metallo-β-Lactamase Classes by Maintaining a Conserved Binding Mode	16
Ex Vivo Phenotypic Screening of Two Small Repurposing Drug Collections Identifies Nifuratel as a Potential New Treatment against Visceral and Cutaneous Leishmaniasis	16
Induction of Endogenous Antibody Recruitment to the Surface of the Pathogen Enterococcus faecium	16
Cowpea Mosaic Virus Nanoparticle Vaccine Candidates Displaying Peptide Epitopes Can Neutralize the Severe Acute Respiratory Syndrome Coronavirus	16
Selenium Derivatives as Promising Therapy for Chagas Disease: In Vitro and In Vivo Studies	15
Modular Synthetic Routes to Fluorine-Containing Halogenated Phenazine and Acridine Agents That Induce Rapid Iron Starvation in Methicillin-Resistant Staphylococcus aureus Biofilms	15
Targeting a Potential G-Quadruplex Forming Sequence Found in the West Nile Virus Genome by Complementary Gamma-Peptide Nucleic Acid Oligomers	15
Structure–Activity Studies with Bis-Amidines That Potentiate Gram-Positive Specific Antibiotics against Gram-Negative Pathogens	15
Hyper-Synergistic Antifungal Activity of Rapamycin and Peptide-Like Compounds against Candida albicans Orthogonally via Tor1 Kinase	15
Repositioning and Characterization of 1-(Pyridin-4-yl)pyrrolidin-2-one Derivatives as Plasmodium Cytoplasmic Prolyl-tRNA Synthetase Inhibitors	15
Virus-like Particle Display of Vibrio cholerae O-Specific Polysaccharide as a Potential Vaccine against Cholera	15
No-Observed-Effect Level of Silver Phosphate in Carbonate Apatite Artificial Bone on Initial Bone Regeneration	15
DNA-Dependent Binding of Nargenicin to DnaE1 Inhibits Replication in Mycobacterium tuberculosis	15
Design, Synthesis, and Biological Evaluation of Light-Activated Antibiotics	15
Areas of Metabolomic Exploration for Helminth Infections	15
Structure–Activity Relationships of the Enterococcal Cytolysin	15
Fragment-Based Identification of Ligands for Bromodomain-Containing Factor 3 of Trypanosoma cruzi	15
Development of Antimicrobial Peptide–Antibiotic Conjugates to Improve the Outer Membrane Permeability of Antibiotics Against Gram-Negative Bacteria	15
PEP27-2, a Potent Antimicrobial Cell-Penetrating Peptide, Reduces Skin Abscess Formation during Staphylococcus aureus Infections in Mouse When Used in Combination with Antibiotics	15
Identification of β-Lactams Active against Mycobacterium tuberculosis by a Consortium of Pharmaceutical Companies and Academic Institutions	15
Resveratrol Attenuates Meningitic Escherichia coli-Mediated Blood–Brain Barrier Disruption	15
Multicationic Quaternary Ammonium Compounds: A Framework for Combating Bacterial Resistance	15
Synergy of the Polymyxin-Chloramphenicol Combination against New Delhi Metallo-β-Lactamase-Producing Klebsiella pneumoniae Is Predominately Driven by Chloramphenicol	15
Current Development of Thiazole-Containing Compounds as Potential Antibacterials against Methicillin-Resistant Staphylococcus aureus	14
Small-Molecular Adjuvants with Weak Membrane Perturbation Potentiate Antibiotics against Gram-Negative Superbugs	14
Combining Cell Envelope Stress Reporter Assays in a Screening Approach to Identify BAM Complex Inhibitors	14
Gallium Porphyrin and Gallium Nitrate Reduce the High Vancomycin Tolerance of MRSA Biofilms by Promoting Extracellular DNA-Dependent Biofilm Dispersion	14
Indole Facilitates Antimicrobial Uptake in Bacteria	14
Random Peptide Mixtures as Safe and Effective Antimicrobials against Pseudomonas aeruginosa and MRSA in Mouse Models of Bacteremia and Pneumonia	14

From Magic Bullet to Magic Bomb: Reductive Bioactivation of Antiparasitic Agents	14
Discovery of a Potent and Selective Chikungunya Virus Envelope Protein Inhibitor through Computer-Aided Drug Design	14
Variable Susceptibility to Gallium Compounds of Major Cystic Fibrosis Pathogens	14
Polymyxin Stereochemistry and Its Role in Antibacterial Activity and Outer Membrane Disruption	14
Conjugation of Aztreonam, a Synthetic Monocyclic β-Lactam Antibiotic, to a Siderophore Mimetic Significantly Expands Activity Against Gram-Negative Bacteria	14
Deazapurine Nucleoside Analogues for the Treatment of Trichomonas vaginalis	14
The Acinetobacter baumannii Autotransporter Adhesin Ata Recognizes Host Glycans as High-Affinity Receptors	14
Two-Way Regulation of MmpL3 Expression Identifies and Validates Inhibitors of MmpL3 Function in Mycobacterium tuberculosis	14
Antimicrobial Susceptibility Testing of Antimicrobial Peptides Requires New and Standardized Testing Structures	14
Anti-persister and Anti-biofilm Activity of Self-Assembled Antimicrobial Peptoid Ellipsoidal Micelles	14
Antibiofilm Activity of Human Milk Oligosaccharides against Multidrug Resistant and Susceptible Isolates of Acinetobacter baumannii	14
Adjuvant-Protein Conjugate Vaccine with Built-In TLR7 Agonist on S1 Induces Potent Immunity against SARS-CoV-2 and Variants of Concern	14
Vitamin D and Streptococci: The Interface of Nutrition, Host Immune Response, and Antimicrobial Activity in Response to Infection	14
Preclinical Evaluation of Inhalational Spectinamide-1599 Therapy against Tuberculosis	14
Salicylanilides Reduce SARS-CoV-2 Replication and Suppress Induction of Inflammatory Cytokines in a Rodent Model	14
Restoring and Enhancing the Potency of Existing Antibiotics against Drug-Resistant Gram-Negative Bacteria through the Development of Potent Small-Molecule Adjuvants	13
Probing the Surface of a Parasite Drug Target Thioredoxin Glutathione Reductase Using Small Molecule Fragments	13
HIV-1 Integrase Inhibitors with Modifications That Affect Their Potencies against Drug Resistant Integrase Mutants	13
Cyclic Tetrapeptide HDAC Inhibitors with Improved Plasmodium falciparum Selectivity and Killing Profile	13
miR-146a Protects against Staphylococcus aureus-Induced Osteomyelitis by Regulating Inflammation and Osteogenesis	13
Alterations to the Cardiac Metabolome Induced by Chronic T. cruzi Infection Relate to the Degree of Cardiac Pathology	13
Antisense Peptide Nucleic Acid–Diaminobutanoic Acid Dendron Conjugates with SbmA-Independent Antimicrobial Activity against Gram-Negative Bacteria	13
Spiro-β-lactam BSS-730A Displays Potent Activity against HIV and Plasmodium	13
Uptake Mechanisms and Regulatory Responses to MECAM- and DOTAM-Based Artificial Siderophores and Their Antibiotic Conjugates in Pseudomonas aeruginosa	13
Immunogenicity Assessment of Cell Wall Carbohydrates of Group A Streptococcus via Self-Adjuvanted Glyco-lipopeptides	13
Resistance-Guided Discovery of Elfamycin Antibiotic Producers with Antigonococcal Activity	13
Drug-Repurposing Screening Identified Tropifexor as a SARS-CoV-2 Papain-like Protease Inhibitor	13
Discovery of Piperidol Derivatives for Combinational Treatment of Azole-Resistant Candidiasis	13
Phosphate Ions Alter the Binding of Daptomycin to Living Bacterial Cell Surfaces	13
Influence of Lipophilicity on the Antibacterial Activity of Polymyxin Derivatives and on Their Ability to Act as Potentiators of Rifampicin	13
Structure, In Vivo Detection, and Antibacterial Activity of Metabolites of SQ109, an Anti-Infective Drug Candidate	13
Gut Microbe-Derived Outer Membrane Vesicles: A Potential Platform to Control Cecal Load of Campylobacter jejuni	13
The CARB-X Portfolio of Nontraditional Antibacterial Products	12
Lipid-Polymer Hybrid Nanoparticles Enhance the Potency of Ampicillin against Enterococcus faecalis in a Protozoa Infection Model	12
Evaluation of Commercially Available Anthelminthics in Laboratory Models of Human Intestinal Nematode Infections	12
Systematic Analyses of the Resistance Potential of Drugs Targeting SARS-CoV-2 Main Protease	12
Fused in Liposarcoma Protein, a New Player in the Regulation of HIV-1 Transcription, Binds to Known and Newly Identified LTR G-Quadruplexes	12
Liposome Delivery of Nucleic Acids in Bacteria: Toward In Vivo Labeling of Human Microbiota	12
Serinc5 Restricts HIV Membrane Fusion by Altering Lipid Order and Heterogeneity in the Viral Membrane	12
Tea Tree Oil Nanoemulsion Potentiates Antibiotics against Multidrug-Resistant Escherichia coli	12
A Coumarin-Based Analogue of Thiacetazone as Dual Covalent Inhibitor and Potential Fluorescent Label of HadA in Mycobacterium tuberculosis	12
Transcriptomic Analysis in Human Macrophages Infected with Therapeutic Failure Clinical Isolates of Leishmania infantum	12
n-Butanol Potentiates Subinhibitory Aminoglycosides against Bacterial Persisters and Multidrug-Resistant MRSA by Rapidly Enhancing Antibiotic Uptake	12
Nanoparticulate β-Cyclodextrin with Gallium Tetraphenylporphyrin Demonstrates in Vitro and in Vivo Antimicrobial Efficacy against Mycobacteroides abscessus and Mycobacterium avium	12
Structure-Based Design of α-Substituted Mercaptoacetamides as Inhibitors of the Virulence Factor LasB from Pseudomonas aeruginosa	12
Pyridinium Modified Anthracenes and Their Endoperoxides Provide a Tunable Scaffold with Activity against Gram-Positive and Gram-Negative Bacteria	12
A Diverse Range of Hemozoin Inhibiting Scaffolds Act on Plasmodium falciparum as Heme Complexes	12
Functional Study of Leishmania braziliensis Protein Arginine Methyltransferases (PRMTs) Reveals That PRMT1 and PRMT5 Are Required for Macrophage Infection	12
Measurement of Small Molecule Accumulation into Diderm Bacteria	12
High-Throughput Immunochemical Method to Assess the 2-Heptyl-4-quinolone Quorum Sensing Molecule as a Potential Biomarker of Pseudomonas aeruginosa Infections	12
Perspective on Schistosomiasis Drug Discovery: Highlights from a Schistosomiasis Drug Discovery Workshop at Wellcome Collection, London, September 2022	12
Synthesis and Antimicrobial Evaluation of New Cephalosporin Derivatives Containing Cyclic Disulfide Moieties	12
Identification of Inhibitors of Fungal Fatty Acid Biosynthesis	12
New Amidated 3,6-Diphenylated Imidazopyridazines with Potent Antiplasmodium Activity Are Dual Inhibitors of Plasmodium Phosphatidylinositol-4-kinase and cGMP-Dependent Protein Kinase	12
Acinetobacter baumannii Fatty Acid Desaturases Facilitate Survival in Distinct Environments	12
Combining Gallium Protoporphyrin and Gallium Nitrate Enhances In Vitro and In Vivo Efficacy against Pseudomonas aeruginosa: Role of Inhibition of Bacterial Antioxidant Enzymes and	12
Docusate-Based Ionic Liquids of Anthelmintic Benzimidazoles Show Improved Pharmaceutical Processability, Lipid Solubility, and in Vitro Activity against Cryptococcus neoformans	12
Chemical Optimization of Selective Pseudomonas aeruginosa LasB Elastase Inhibitors and Their Impact on LasB-Mediated Activation of IL-1β in Cellular and Animal Infection Models	12
Serum Prevents Interactions between Antimicrobial Amphiphilic Aminoglycosides and Plasma Membranes	12
Targeted Protein Degradation: The New Frontier of Antimicrobial Discovery?	11
Development of Inhibitors of SAICAR Synthetase (PurC) from Mycobacterium abscessus Using a Fragment-Based Approach	11
Structural Requirements for Dihydrobenzoxazepinone Anthelmintics: Actions against Medically Important and Model Parasites: Trichuris muris, Brugia malayi, Heligmosomoides polygyrus	11
HPMCAS-Coated Alginate Microparticles Loaded with Ctx(Ile21)-Ha as a Promising Antimicrobial Agent against Salmonella Enteritidis in a Chicken Infection Model	11
Disruption of Metallostasis in the Anaerobic Human Pathogen Fusobacterium nucleatum by the Zinc Ionophore PBT2	11
Inhibition of Pseudomonas aeruginosa Alginate Synthesis by Ebselen Oxide and Its Analogues	11
Identification of 2-Aryl-Quinolone Inhibitors of Cytochrome bd and Chemical Validation of Combination Strategies for Respiratory Inhibitors against Mycobacterium tuberculosis	11
Synthesis and Antibacterial Activity of Propylamycin Derivatives Functionalized at the 5′′- and Other Positions with a View to Overcoming Resistance Due to Aminoglycoside Modifying Enzymes	11
Kinetic Characterization of SARS-CoV-2 nsp13 ATPase Activity and Discovery of Small-Molecule Inhibitors	11
Indirect Mechanisms of HIV-1 Evasion from Broadly Neutralizing Antibodies In Vivo	11
Enhancement of the Antifungal Activity of Chitinase by Palmitoylation and the Synergy of Palmitoylated Chitinase with Amphotericin B	11
Liquid Crystal Nanoparticles Enhance Tobramycin Efficacy in a Murine Model of Pseudomonas aeruginosa Biofilm Wound Infection	11
Small-Molecule Antibiotic Drug Development: Need and Challenges	11
Switching Bond: Generation of New Antimicrobial Peptides via the Incorporation of an Intramolecular Isopeptide Bond	11
Assessing In Vitro Resistance Development in Enterovirus A71 in the Context of Combination Antiviral Treatment	11
Development of Amphiphilic Coumarin Derivatives as Membrane-Active Antimicrobial Agents with Potent In Vivo Efficacy against Gram-Positive Pathogenic Bacteria	11
Interactions of the Diazabicyclooctane Serine β-Lactamase Inhibitor ETX1317 with Target Enzymes	11
Oral Efficacy of a Diselenide Compound Loaded in Nanostructured Lipid Carriers in a Murine Model of Visceral Leishmaniasis	11
Azaindole Based Potentiator of Antibiotics against Gram-Negative Bacteria	11
A Screen of Natural Product Extracts Identifies Moenomycin as a Potent Antigonococcal Agent	10
hACE2-Induced Allosteric Activation in SARS-CoV versus SARS-CoV-2 Spike Assemblies Revealed by Structural Dynamics	10
Insights into the Spectrum of Activity and Mechanism of Action of MGB-BP-3	10
Synthesis and Application of Rare Deoxy Amino l-Sugar Analogues to Probe Glycans in Pathogenic Bacteria	10
Characterization and Inhibition of 1-Deoxy-d-Xylulose 5-Phosphate Reductoisomerase: A Promising Drug Target in Acinetobacter baumannii and Klebsiella pneumoniae	10
Glycomic Analysis Reveals a Conserved Response to Bacterial Sepsis Induced by Different Bacterial Pathogens	10
Inhibitors of HIV-1 Nef-Mediated Activation of the Myeloid Src-Family Kinase Hck Block HIV-1 Replication in Macrophages and Disrupt MHC-I Downregulation	10
Hijacking of the Enterobactin Pathway by a Synthetic Catechol Vector Designed for Oxazolidinone Antibiotic Delivery in Pseudomonas aeruginosa	10
Transferring Microclusters of P. aeruginosa Biofilms to the Air–Liquid Interface of Bronchial Epithelial Cells for Repeated Deposition of Aerosolized Tobramycin	10
Ligand Recognition by the Lipid Transfer Domain of Human OSBP Is Important for Enterovirus Replication	10
Antibodies That Engage the Hemagglutinin Receptor-Binding Site of Influenza B Viruses	10
Identification of Evolutionary Trajectories Associated with Antimicrobial Resistance Using Microfluidics	10
QM/MM Simulations Reveal the Determinants of Carbapenemase Activity in Class A β-Lactamases	10
Human B Cell Epitope Map of the Lyme Disease Vaccine Antigen, OspA	10
Random Forest Model Predictions Afford Dual-Stage Antimalarial Agents	10
Detection of Bacterial Coinfection in COVID-19 Patients Is a Missing Piece of the Puzzle in the COVID-19 Management in Indonesia	10
Bioluminescent Imaging Identifies Thymus, As Overlooked Colonized Organ, in a Chronic Model of Leishmania donovani Mouse Visceral Leishmaniasis	10