OOIR: Observatory of International Research

Papers

(The TQCC of ACS Infectious Diseases is 8. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)

Article	Citations
Issue Editorial Masthead	172
Contact Dynamics of Cytoadhering Plasmodium falciparum-Infected Erythrocytes in Flow	118
Issue Publication Information	111
Virulence and Adhesion of the Treponema pallidum Nichols Strain Simultaneously Decrease in a Continuous-Infection New Zealand White Rabbit Model	100
Ebola Virus Glycoprotein Impairs Human Retinal Pigment Epithelial Barrier Function via the PI3K/Akt-Nrf2 Pathway	98
Role of Macrophage PIST Protein in Regulating Leishmania major Infection	87
Mutagenesis-Guided Target Identification Reveals the Protein-Binding Domain of Nsp14 in Coronaviruses as the Target of a Labdane-Oxindole Compound	82
Treponema pallidum Protein TpF1 Inhibits Migration by Impairing Actin Polymerization via Toll-Like Receptor 4/PI3K/AKT in Microglia	79
Smart Wound Dressing with Real-Time Colorimetric Detection of Antimicrobial Resistance and Infection	77
Enhanced Antimicrobial Screening Sensitivity Enabled the Identification of an Ultrashort Peptide KR-8 for Engineering of LL-37mini to Combat Drug-Resistant Pathogens	75
Deciphering the Role of pafBC in Mycobacteriophage Resistance and Biofilm Formation	66
The Quorum Sensing-Controlled Competence Regulon Drives H ₂ O ₂ Production in	66
Heterogeneity and Compositional Diversities of Campylobacter jejuni Outer Membrane Vesicles (OMVs) Drive Multiple Cellular Uptake Processes	55
Correction to “Serotype-Specific Regulation of Dengue Virus NS5 Protein Subcellular Localization”	45
Biochemical and Cellular Characterization of the Function of Fluorophosphonate-Binding Hydrolase H (FphH) in Staphylococcus aureus Support a Role in Bacterial Stress Response	45
High-Throughput Profiling of Bacterial Glycans: Evolving Microarray Technologies and Applications	44
Students Against Superbugs (SAS) Africa	42
Teichoic Acids Play a Key Role in the Antibacterial Activity of Big Defensins against Staphylococcus aureus	42
Phenotypic Landscape of Immune Cells in Sepsis: Insights from High-Dimensional Mass Cytometry	41
Mitophagy Activation Targeting PINK1 Is an Effective Treatment to Inhibit Zika Virus Replication	40
Starved of ACTION: A Critical Look at the Antimicrobial Resistance Action Plans of African Countries	37
Efficient Synthesis of Clovibactin and Its Analogues: Promoting the Discovery of More Potent Antibiotics via Multiple Screenings	37
Protein O-Fucosyltransferase Is Required for the Efficient Invasion of Hepatocytes by Plasmodium berghei Sporozoites	36
Antibiotic Repurposing: Conjugation of the Gram-Positive Only Peptide Antibiotic Bacitracin to a Bis-Catechol Siderophore Mimetic Imparts Potent Activity against Multi-Drug Resistant	36
1,3-Diarylpyrazolyl-acylsulfonamides Target HadAB/BC Complex in Mycobacterium tuberculosis	36

IL-33/ST2 Signaling Protects the Heart by Restraining Inflammation and Parasite Burden during Trypanosoma cruzi Experimental Infection	35
Tea Tree Oil Nanoemulsion Potentiates Antibiotics against Multidrug-Resistant Escherichia coli	35
Disparate Regions of the Human Chemokine CXCL10 Exhibit Broad-Spectrum Antimicrobial Activity against Biodefense and Antibiotic-Resistant Bacterial Pathogens	34
Correction to “Antifungal Efficacy of 3D-Cultured Palatal Mesenchymal Stem Cells and Their Secreted Factors against Candida albicans ”	34
Cholesterol-Dependent Membrane Deformation by Metastable Viral Capsids Facilitates Entry	33
Cytoplasmic Delivery of an Antibiotic, Trimethoprim, with a Simple Bidentate Catechol Analog as a Siderophore Mimetic	33
The Future of Protozoan Infection Research: 3D Cell Culture and beyond	33
DNA Aptamers Mediated Inhibition of Pathogenic Erm42 Enzyme Involved in Antimicrobial Resistance	33
Rapid Enzymatic Detection of Shiga-Toxin-Producing E. coli Using Fluorescence-Labeled Oligonucleotide Substrates	33
Analyses of the Antibiofilm Activity of o-Phenanthroline Monohydrate against Enterococcus faecalis and Staphylococcus aureus and the Mechanisms Underlying These Effects	33
MptpB Inhibitor Improves the Action of Antibiotics against Mycobacterium tuberculosis and Nontuberculous Mycobacterium avium Infections	33
Chitosan-Coated Silver Nanoparticles Inhibit Adherence and Biofilm Formation of Uropathogenic Escherichia coli	32
Restricted Rotational Flexibility of the C5α-Methyl-Substituted Carbapenem NA-1-157 Leads to Potent Inhibition of the GES-5 Carbapenemase	32
Soft QPCs: Biscationic Quaternary Phosphonium Compounds as Soft Antimicrobial Agents	31
Call for Papers: One Health and Vector-Borne Parasitic Diseases	29
Honoring a Legacy: “Vigyan Ratna” Prof. G. Padmanaban	28
Issue Publication Information	26
Issue Publication Information	26
Issue Editorial Masthead	25
Role of the Mobile Active Site Flap in IMP Dehydrogenase Inhibitor Binding	24
Issue Editorial Masthead	24
Evaluation of the Leishmania Inositol Phosphorylceramide Synthase as a Drug Target Using a Chemical and Genetic Approach	24
Infectious Diseases Chemical “Cookbooks”: Celebrating Women’s Authorship in ACS Infectious Diseases	24
Hemolysin Coregulated Protein (HCP) from Vibrio Cholerae Interacts with the Host Cell Actin Cytoskeleton	24
Identification of Prazosin as a Potential Flagellum Attachment Zone 1(FAZ1) Inhibitor for the Treatment of Human African Trypanosomiasis	24
Tigecycline–Rifampicin Restrains Resistance Development in Carbapenem-Resistant Klebsiella pneumoniae	24
Halogenated Sulfono-γ-AApeptides Modified Cationic AMPs Have Enhanced Stability and Therapeutic Potential against Clinically Important MDR Infections	23
Correction to “Differential Immune Responses of Th1 Stimulatory Chimeric Antigens of Leishmania donovani in BALB/c Mice”	23
Studies on Developing a Preclinical Candidate to Fight Helicobacter Pylori Infection	23
Tre-DST: A Drug Susceptibility Test for Mycobacterium tuberculosis Using Solvatochromic Trehalose Probes	22
LABCG1 Affects Leishmania ( Leishmania ) Amazonensis Infect	22
Evaluation of Fusobacterium nucleatum Enoyl-ACP Reductase (FabK) as a Narrow-Spectrum Drug Target	22
Molecular Docking Reveals Critical Residues in Candida albicans Cyr1 for Peptidoglycan Recognition and Hyphal Growth	22
Interplay between Amino Acid Substitution in GyrA and QnrB19: Elevating Fluoroquinolone Resistance in Salmonella Typhimurium	22
In Vivo Activity Profiling of Biosynthetic Darobactin D22 against Critical Gram-Negative Pathogens	21
Functions and Regulation of the Outer Membrane Protein TolC in Vibrio Species	21
Bone-Adhesive Hydrogel for Effective Inhibition of M. tuberculosis and Osteoblast Regeneration	21
Anthelmintic and Antibiotic Therapy Resolves Intestinal Inflammatory Infiltration in Experimental Trichuriasis	21
A Family of Antibiotics That Evades Resistance by Binding Polyprenyl Phosphates	20
hACE2-Induced Allosteric Activation in SARS-CoV versus SARS-CoV-2 Spike Assemblies Revealed by Structural Dynamics	20
Antimicrobial Peptide–Peptoid Hybrids with and without Membrane Disruption	20
Bumped Kinase Inhibitors Inhibit both Toxoplasma gondii MAPKL1 and CDPK1	20
Discovery of 1,3,4-Oxadiazole Derivatives as Broad-Spectrum Antiparasitic Agents	20
Nitazoxanide-Gold Nanoparticles Combat Carbapenem-Resistant Enterobacteriaceae via Membrane Disruption and Oxidative Stress	20
Treponema pallidum Promotes the Polarization of M2 Subtype Macrophages to M1 Subtype Mediating the Apoptosis and Inhibiting the Angiogenesis of Human Umbilical Vein Endothelial Cells	20
Re-sensitization of Multidrug-Resistant and Colistin-Resistant Gram-Negative Bacteria to Colistin by Povarov/Doebner-Derived Compounds	20
Modulators of the Hop-HSP90 Protein–Protein Interaction Disrupt KSHV Lytic Replication	20
Deciphering Divergent Trypanosomatid Nuclear Complexes by Analyzing Interactomic Datasets with AlphaFold2 and Genetic Approaches	20
Label-Free Mass Spectrometry Proteomics Reveals Different Pathways Modulated in THP-1 Cells Infected with Therapeutic Failure and Drug Resistance Leishmania infantum Clinical Isolates	20
Glycoscience in Infectious Diseases Virtual Special Issue	19

Sialic Acid-Containing Glycolipids Extend the Receptor Repertoire of Enterovirus-D68	19
Rv2741 Promotes Mycobacterium Survival by Modulating Macrophage Function via the IL-1α-MAPK Axis	19
Identification of Innovative Folate Inhibitors Leveraging the Amino Dihydrotriazine Motif from Cycloguanil for Their Potential as Anti-Trypanosoma brucei Agents	19
Synthesis, Antibacterial Activity, and Nephrotoxicity of Polymyxin B Analogues Modified at Leu-7, d-Phe-6, and the N-Terminus Enabled by S-Lipidation	19
Dual-Site Inhibition of SARS-CoV-2 RNA-Dependent RNA Polymerase by Small Molecules Able to Block Viral Replication Identified through a Computer-Aided Drug Discovery Approach	19
Marine Guanidine Alkaloids Inhibit Malaria Parasites Development in In Vitro, In Vivo and Ex Vivo Assays	19
FABP5 Inhibitor Attenuates HPV11 Pseudovirion Infection by Reducing Lipid Droplet Formation	18
Exploring the Localization of Siderophore-Mediated Cargo Delivery in Gram-Negative Bacteria Using 3-Hydroxypyridin-4(1H)-one-Fluorescein Probes	18
Netupitant Exhibits Potent Activity on Mycobacterium tuberculosis Persisters	18
Streptococcus agalactiae cadD Is Critical for Pathogenesis in the Invertebrate Galleria mellonella Model	18
Issue Editorial Masthead	18
Immunoproteomic and Immunoinformatic Approaches Identify Sensitive Antigens for Diagnosing Anisakis pegreffii Infection	18
d-[5-¹¹C]-Glutamine Positron Emission Tomography Imaging for Diagnosis and Therapeutic Monitoring of Orthopedic Implant Infections	18
Molecular Signatures of the Eagle Effect Induced by the Artificial Siderophore Conjugate LP-600 in E. coli	18
Unveiling the Antibacterial Efficacy of a Benzonitrile Small Molecule, IITR00210, in Shigella Infection	18
Identification of Polysialic Acid and Chondroitin-like Polysaccharides of Moraxella bovis Strains Associated with Infectious Bovine Keratoconjunctivitis	18
Indirect Mechanisms of HIV-1 Evasion from Broadly Neutralizing Antibodies In Vivo	18
Interleukin-22 Contributes to Blood–Brain Barrier Disruption via STAT3/VEGFA Activation in Escherichia coli Meningitis	18
Modulating Micrococcal Nuclease-Triggered Antibiotic Releases for One-Stage Revisions of Staphylococcus aureus -Infected Prostheses	18
The Impact of Antimicrobial Peptides on the Acinetobacter baumannii Inner Membrane Is Modulated by Lipid Polyunsaturation	17
Exploring the Darobactin Class of Antibiotics: A Comprehensive Review from Discovery to Recent Advancements	17
Tolfenpyrad Modulates Antibiotic Activity on Francisella novicida and Synergizes with Electron Transport Chain Inhibitors	17
Rapid Antibiotic Susceptibility Determination by Fluorescence Lifetime Tracking of Bacterial Metabolism	17
Intracellular Experimental Evolution of Francisella tularensis Subsp. holarctica Live Vaccine Strain (LVS) to Antimicrobial Resistance	17
Flavopiridol Protects against Fungal Keratitis due to Aspergillus fumigatus by Alleviating Inflammation through the Promotion of Autophagy	17
Antibacterial Photodynamic Therapy in the Near-Infrared Region with a Targeting Antimicrobial Peptide Connected to a π-Extended Porphyrin	17
Potent Inhibition of E. coli DXP Synthase by a gem-Diaryl Bisubstrate Analog	17
Identification of and Structural Insights into Hit Compounds Targeting N-Myristoyltransferase for Cryptosporidium Drug Development	17
Identification and Characterization of a Small-Molecule Inhibitor of the Pseudomonas aeruginosa SOS Response	17
Revised Model for the Type A Glycan Biosynthetic Pathway in Clostridioides difficile Strain 630Δerm Based on Quantitative Proteomics of cd0241–cd0244 Mutant Strains	17
Mtb-Selective 5-Aminomethyl Oxazolidinone Prodrugs: Robust Potency and Potential Liabilities	17
k_inact/K_I Value Determination for Penicillin-Binding Proteins in Live Cells	17
An ApiAp2 Transcription Factor with a Dispensable Role in Plasmodium berghei Life Cycle	17
Legacy 4(1 H )-Quinolone Scaffolds Activity against Acute and Chronic Toxoplasma gondii Infection	17
Systematic Analyses of the Resistance Potential of Drugs Targeting SARS-CoV-2 Main Protease	17
Raman Fingerprints of the SARS-CoV-2 Delta Variant and Mechanisms of Its Instantaneous Inactivation by Silicon Nitride Bioceramics	17
GaSal-2: A Water-Soluble Antipseudomonal Agent Targeting the Extracellular Hemophore HasAp	16
Issue Publication Information	16
Investigating the Translational Value of Periprosthetic Joint Infection Models to Determine the Risk and Severity of Staphylococcal Biofilms	16
Immunomodulatory Nanoparticles Induce Autophagy in Macrophages and Reduce Mycobacterium tuberculosis Burden in the Lungs of Mice	16
Long-Term Neuroimaging Findings in a Murine Model of Human Extraparenchymal Neurocysticercosis	16
Issue Publication Information	16
Benzene Amide Ether Scaffold is Active against Non-replicating and Intracellular Mycobacterium tuberculosis	16
Discovery, Synthesis, and Optimization of 1,2,4-Triazolyl Pyridines Targeting Mycobacterium tuberculosis	16
Host–Pathogen Cellular Communication: The Role of Dynamin, Clathrin, and Macropinocytosis in the Uptake of Giardia-Derived Extracellular Vesicles	16
Understanding the Antiplasmodial Action of Resistance-Refractory Xanthoquinodin A1	16
The Forgotten Pioneer	16
Adjuvant-Protein Conjugate Vaccine with Built-In TLR7 Agonist on S1 Induces Potent Immunity against SARS-CoV-2 and Variants of Concern	16
Potency of CRISPR-Cas Antifungals Is Enhanced by Cotargeting DNA Repair and Growth Regulatory Machinery at the Genetic Level	16
Identifying Rab2 Protein as a Key Interactor of Centrin1 Essential for Leishmania donovani Growth	15
Gut Microbiota and COVID-19: Unraveling the Gut–Lung Axis and Immunomodulatory Therapies	15
Polymyxin Stereochemistry and Its Role in Antibacterial Activity and Outer Membrane Disruption	15
Development of Broad-Spectrum Antimicrobial Peptides through the Conjugation of FtsZ-Binding and Cell-Penetrating Peptides	15
Spermidine Associated with Gut Microbiota Protects Against MRSA Bloodstream Infection by Promoting Macrophage M2 Polarization	15
Key Facets for the Elimination of Vector-Borne Diseases Filariasis, Leishmaniasis, and Malaria	15
A Novel Thiopeptide Exhibits In Vitro and In Vivo Synergistic Antibacterial Activity with Macrolide Against Mycobacterium avium Complex Infection	15
Identification of α-Azacyclic Acetamide-Based Inhibitors of P. falciparum Na ⁺ Pump (	15
Guanidinylated Amphiphilic Tobramycin Derivatives Synergize with β-Lactam/β-Lactamase Inhibitor Combinations against Pseudomonas aeruginosa	15
Synthesis and Biological Activities of Oxazolidinone Pleuromutilin Derivatives as a Potent Anti-MRSA Agent	15
Bcl-2 Antagonist Obatoclax Reactivates Latent HIV-1 via the NF-κB Pathway and Induces Latent Reservoir Cell Apoptosis in Latently Infected Cells	14
Label-Free Citrate-Stabilized Silver Nanoparticles-Based, Highly Sensitive, Cost-Effective, and Rapid Visual Method for the Differential Detection of Mycobacterium tuberculosis and Mycobacte	14
Imbalanced EphB4/EphrinB2 Signaling Modulates Bone Resorption in Periodontitis Induced by Porphyromonas gingivalis	14
Activity-Based Protein Profiling Identifies an α-Amylase Family Protein Contributing to the Virulence of Methicillin-Resistant Staphylococcus aureus	14
Thiazole Derivatives as Promising Candidates for Cryptococcosis Therapy	14
Exploring the Role of Pseudomonas aeruginosa Elastase in Lung Epithelial Barrier Dysfunction: Advancing toward Antivirulence Therapies	14
Sulfonyl Homoserine Lactones Are Tunable Probes to Inhibit the Quorum Sensing Receptor RhlR and Reduce Swarming Motility in Pseudomonas aeruginosa	14
Multifunctional Nanosystem for Dual Anti-Inflammatory and Antibacterial Photodynamic Therapy in Infectious Diabetic Wounds	14
Valorizing Constituents of Cashew Nut Shell Liquid toward the Sustainable Development of New Drugs against Chagas Disease	14
RaMoA: Raman Microspectroscopy and Deep Learning for the Classification of Antimicrobial Mechanism of Action	14
Studying Target–Engagement of Anti-Infectives by Solvent-Induced Protein Precipitation and Quantitative Mass Spectrometry	14
Recombinant Human IgG1 Enhances Complement-Mediated Bacteriolysis and Macrophage Phagocytosis of Pseudomonas aeruginosa via Targeting Cell Surface Polysa	14
Structure-Based Ligand Design Targeting Pseudomonas aeruginosa LpxA in Lipid A Biosynthesis	14
A Divergent MBL-Fold Metallo-Hydrolase (Kmh-1) from Klebsiella pneumoniae Confers Aztreonam Degradation and Expands the β-Lactamase Landscape	14
Genetic Characterization of Trypanosoma cruzi I Populations from an Oral Chagas Disease Outbreak in Venezuela: Natural Resistance to Nitroheterocyclic Drugs	14
Quantifying Membrane Alterations with Tailored Fluorescent Dyes: A Rapid Antibiotic Resistance Profiling Methodology	14
Decarboxylation of the Catalytic Lysine Residue by the C5α-Methyl-Substituted Carbapenem NA-1-157 Leads to Potent Inhibition of the OXA-58 Carbapenemase	14
Ten Years of ACS Infectious Diseases – A Celebration of Excellence	14
Effectiveness of Two New Endochin-like Quinolones, ELQ-596 and ELQ-650, in Experimental Mouse Models of Human Babesiosis	14
Negamycin: Nature’s Forgotten Antibiotic	14
Naphthalene Diimide–Tetraazacycloalkane Conjugates Are G-Quadruplex-Based HIV-1 Inhibitors with a Dual Mode of Action	14

Difference in the Inhibitory Effect of Thiol Compounds and Demetallation Rates from the Zn(II) Active Site of Metallo-β-lactamases (IMP-1 and IMP-6) Associated with a Single Amino Acid Substitution	14
Breaking the Cycle: Matrix Metalloproteinase Inhibitors as an Alternative Approach in Managing Tuberculosis Pathogenesis and Progression	14
Development of a Promising Ferritin-Based Bioconjugate Nanovaccine Candidate against Brucellosis	13
Cyclometalated Iridium(III) Complexes with eDNA-Degrading Activity for Combating Gram-Positive Bacterial Biofilms	13
Treponema pallidum Impairs Microglial Aβ ₁ _– ₄ ₂	13
Discovery of 2,4,5-Substituted Benzoxazole Derivatives as Pks13 Inhibitors via the Scaffold Hopping Strategy	13
Structural Basis for Cyclosporin Isoform-Specific Inhibition of Cyclophilins from Toxoplasma gondii	13
Synthesis and Biological Evaluation of Cyanoacrylamides and 5-Iminopyrrol-2-Ones Against Naegleria fowleri	13
Discovery of Potent DAG-Lactone Derivatives as HIV Latency Reversing Agents	13
A pH Fingerprint Assay to Identify Inhibitors of Multiple Validated and Potential Antimalarial Drug Targets	13
Unanticipated Lipid Redistribution Mechanism of Action by Conjugated Oligoelectrolyte Antibiotics	13
Protective Humoral Immune Response Induced by Recombinant Virus-like Particle Vaccine Expressing Leishmania donovani Surface Antigen	13
Antifungal Tetrahydrocarbazole Compound CAR-8 Induces Endoplasmic Reticulum Stress in Candida albicans	13
Antibiotic Delivery System for Treating Bacteria-Induced Anterior Blepharitis	13
Discovery and Development of Antibacterial Peptidoglycan Hydrolase Inhibitors	13
PAK1 Promotes Inflammation Induced by Sepsis through the Snail/CXCL2 Signaling Pathway	13
Discovery of A-967079 as an Enterovirus D68 Antiviral by Targeting the Viral 2C Protein	13
Electrochemical Immunoassay for Capturing Capsular Polysaccharide of Burkholderia pseudomallei: Early Onsite Detection of Melioidosis	13
Human Kinase IGF1R/IR Inhibitor Linsitinib Controls the In Vitro and Intracellular Growth of Mycobacterium tuberculosis	13
Neutrophil-Leishmania infantum Interaction Induces Neutrophil Extracellular Traps, DAMPs, and Inflammatory Molecule Release	13
Anti-SARS-CoV-2 Small Molecule Targeting of Oxysterol-Binding Protein (OSBP) Activates Cellular Antiviral Innate Immunity	13
Toolkit of Approaches To Support Target-Focused Drug Discovery for Plasmodium falciparum Lysyl tRNA Synthetase	12
Recent Advances in the Development of Polymyxin Antibiotics: 2010–2023	12
Gelatin–Gallic Acid Microcomplexes Release GO/Cu Nanomaterials to Eradicate Antibiotic-Resistant Microbes and Their Biofilm	12
Repurposing GSK2018682 Confers Dual Antibacterial and Antibiofilm Activity against Staphylococcus aureus	12
Recent Advances in Pleuromutilin Derivatives as Antimicrobial Agents (2015–2025)	12
Investigation of the Potential Targets behind the Promising and Highly Selective Antileishmanial Action of Synthetic Flavonoid Derivatives	12
Xanthone Derivatives Enhance the Therapeutic Potential of Neomycin against Polymicrobial Gram-Negative Bacterial Infections	12
Biophysics-Guided Lead Discovery of HBV Capsid Assembly Modifiers	12
Issue Publication Information	12
Antimicrobial Potency of Nor-Pyochelin Analogues and Their Cation Complexes against Multidrug-Resistant Pathogens	12
Loratadine Combats Methicillin-Resistant Staphylococcus aureus by Modulating Virulence, Antibiotic Resistance, and Biofilm Genes	12
Measuring Membrane Fluidity in Live Mycobacteria Reveals Subcellular Lateral Variation And Pole-Selective Responses to Mycomembrane Perturbation	12
Perspective on Schistosomiasis Drug Discovery: Highlights from a Schistosomiasis Drug Discovery Workshop at Wellcome Collection, London, September 2022	12
Lusutrombopag as a Repurposing Drug in Combination with Aminoglycosides against Vancomycin-Resistant Enterococcus	12
Role of Ambler Position 104 in Defining Substrate Specificity in the KPC Family of β-Lactamases	12
Multidrug-Resistant Acinetobacter baumannii : A Wily, Existential Threat to Modern Healthcare	12
ASLdC3: A Derivative of Acidic Sophorolipid Disrupts Mitochondrial Function, Induces ROS Generation, and Inhibits Biofilm Formation in Candida albicans	12
Green-Synthesized Amino Carbons for Impedimetric Biosensing of E. coli O157:H7	12
Targeting G3BP1-Mediated Stress Granules to Suppress SARS-CoV-2 Replication	12
Accelerating Antimalarial Drug Discovery with a New High-Throughput Screen for Fast-Killing Compounds	12
Issue Editorial Masthead	12
MicroRNA-144-3p Inhibits Host Lipid Catabolism and Autophagy by Targeting PPARα and ABCA1 During Mycobacterium Tuberculosis Infection	12
Infection and the Glycome─New Insights into Host Response	11
Influence of Steric and Electronic Properties of P2 Groups on Covalent Inhibitor Binding to SARS-CoV-2 Main Protease	11
Two Years into the COVID-19 Pandemic: Lessons Learned	11
Molecular Mechanism of pH-Induced Protrusion Configuration Switching in Piscine Betanodavirus Implies a Novel Antiviral Strategy	11
Synthesis, Stereochemical Resolution, and Analogue Synthesis of Variabiline, an Aporphine Alkaloid That Sensitizes Acinetobacter baumannii and Klebsiella pneumoniae to Colistin	11
β-Lactamase-Mediated Fragmentation: Historical Perspectives and Recent Advances in Diagnostics, Imaging, and Antibacterial Design	11
Loratadine Derivative Lo-7: A Weapon against Drug-Resistant Enterococcus and Streptococcal Infections	11
SIRT1 and SIRT3 Impact Host Mitochondrial Function and Host Salmonella pH Balance during Infection	11
Group B Streptococcal Membrane Vesicles Induce Proinflammatory Cytokine Production and Are Sensed in an NLRP3 Inflammasome-Dependent Mechanism in a Human Macrophage-like Cell Line	11
Identification and Evaluation of Dibasic Piperidines as Cell Wall Inhibitors against Mycobacterium tuberculosis	11
Playing Telephone: How Secondary Messengers Influence Host–Pathogen Interactions in Tuberculosis	11
Inhibitors of the Structural and Nonstructural Proteins of Alphaviruses	11
Florasulam Is a Potent Inhibitor of Mycobacterium tuberculosis Acetohydroxyacid Synthase and Possesses In Vivo Antituberculosis Activity	11
Antiviral Activity of the Acyclic Nucleoside Phosphonate Prodrug LAVR-289 against Poxviruses and African Swine Fever Virus	11
In Vivo Antileishmanial Effect of 3,5-Diaryl-isoxazole Analogues Based on Veraguensin, Grandisin, and Machilin G: A Glance at a Preclinical Study	11
Rapid and Ultrasensitive Detection of Plasmodium spp. Parasites via the RPA-CRISPR/Cas12a Platform	11
Correction to “A Bifunctional Chemical Reporter for in Situ Analysis of Cell Envelope Glycan Recycling in Mycobacteria”	11
Glycoblotting-Based Ovo-Sulphoglycomics Reveals Phosphorylated N-Glycans as a Possible Host Factor of AIV Prevalence in Waterfowls	11
Structural Basis for Postfusion-Specific Binding to the Respiratory Syncytial Virus F Protein by the Canonical Antigenic Site I Antibody 131–2a	11
Role of RNA G-Quadruplexes in the Japanese Encephalitis Virus Genome and Their Recognition as Prospective Antiviral Targets	10
Measurement of Small Molecule Accumulation into Diderm Bacteria	10
Mechanistic Insights into Cellular and Molecular Targets of Zinc Oxide Quantum Dots (ZnO QDs) in Fungal Pathogen, Candida albicans: One Drug Multi-Targeted Therapeutic Approach	10
Establishment of a CRISPR/Cas12b-Based Multiple Cross Displacement Amplification Assay for the Rapid, Sensitive, and Specific Detection of Brucella ovis	10
A New 1,2,3-Triazole Scaffold with Improved Potency against Staphylococcus aureus Biotin Protein Ligase	10
Investigations of Thiosemicarbazides as Botulinum Toxin Active-Site Inhibitors: Enzyme, Cellular, and Rodent Intoxication Studies	10
Chemoenzymatic Synthesis of SARS-CoV-2 Homogeneous O-Linked Glycopeptides for Exploring Their Inhibition Functions	10
Extracellular vesicles from Distinct Histoplasma capsulatum Strains Modulate Phagocyte Function and Promote Fungal Persistence	10
SuperBola Cationic Biocides with an Extended Bolaamphiphilic Structure: How Much Is Too Much?	10
Intranasal Self-Adjuvanted Lipopeptide Vaccines Elicit High Antibody Titers and Strong Cellular Responses against SARS-CoV-2	10
Issue Publication Information	10
Gallium Protoporphyrin and Lipid Crystalline Nanoparticles Promote the Activity of Ampicillin against MRSA	10
7-N-Substituted-3-oxadiazole Quinolones with Potent Antimalarial Activity Target the Cytochrome bc₁ Complex	10
3-Benzylmenadiones and their Heteroaromatic Analogues Target the Apicoplast of Apicomplexa Parasites: Synthesis and Bioimaging Studies	10
Structural Characterization and Evaluation of an Epitope at the Tip of the A-Band Rhamnan Polysaccharide of Pseudomonas aeruginosa	10
Efficacy and Toxicity Studies of Novel α-MSH Analogues with Antibiofilm Action and β-Lactam Resensitization Potential against MRSA	10
Tree Frog-Derived Cathelicidin Protects Mice against Bacterial Infection through Its Antimicrobial and Anti-Inflammatory Activities and Regulatory Effect on Phagocytes	10
Repurposing Benzbromarone as an Antibacterial Agent against Gram-Positive Bacteria	10
Chemokine CXCL14 Inhibits the Survival of Mycobacterium smegmatis inside Macrophages by Upregulating A20 to Promote ROS Production	10
Issue Editorial Masthead	10
Mechanism of Inhibition of the Active Triphosphate Form of 2′-α-Fluoro,2′-β-bromouridine against Yellow Fever Virus RNA-Dependent RNA Polymerase	10
Rickettsia Aglow: A Fluorescence Assay and Machine Learning Model to Identify Inhibitors of Intracellular Infection	10
Cysteine Reactivity Profiling Identifies Host Regulators of Mycobacterium tuberculosis Replication in Human Macrophages	10
A Cell-Based Screening Assay for rRNA-Targeted Drug Discovery	10
Suite of TMPRSS2 Assays for Screening Drug Repurposing Candidates as Potential Treatments of COVID-19	10
Activity of Antibacterial/Antifungal Compounds against the Protozoan Parasite, Toxoplasma gondii	9
Deciphering Host–Parasite Interplay in Leishmania Infection through a One Health View of Proteomics Studies on Drug Resistance	9
Harnessing the 12 Green Chemistry Principles for Sustainable Antiparasitic Drugs: Toward the One Health Approach	9
Berberine Suppresses Pathogenic Fungus Aspergillus fumigatus Hyphal Growth via Mitochondrial Fragmentation-Induced ROS Elevation and Hog1-MAPK Activation	9
Substrate Analogues Entering the Lipoic Acid Salvage Pathway via Lipoate-Protein Ligase 2 Interfere with Staphylococcus aureus Virulence	9
Beyond Inhibition: Sublethal Rifampicin-Induced Molecular Adaptations Confer Phenotypic Drug Tolerance in Mycobacteria	9
MEPicides: α,β-unsaturated Fosmidomycin N-Acyl Analogs as Efficient Inhibitors of Plasmodium falciparum 1-Deoxy-d-xylulose-5-phosphate reductoisomerase	9
Understanding the Molecular Basis for Homodimer Formation of the Pneumococcal Endolysin Cpl-1	9