ACS Infectious Diseases

Papers
(The median citation count of ACS Infectious Diseases is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-03-01 to 2024-03-01.)
ArticleCitations
Broad Spectrum Antiviral Agent Niclosamide and Its Therapeutic Potential237
Characterization and Noncovalent Inhibition of the Deubiquitinase and deISGylase Activity of SARS-CoV-2 Papain-Like Protease214
Endogenous Deficiency of Glutathione as the Most Likely Cause of Serious Manifestations and Death in COVID-19 Patients182
Proteolytic Activation of SARS-CoV-2 Spike at the S1/S2 Boundary: Potential Role of Proteases beyond Furin120
Anti-SARS-CoV-2 Potential of Artemisinins In Vitro113
Current and Perspective Diagnostic Techniques for COVID-19111
Recent Innovations in Bacterial Infection Detection and Treatment104
Multitarget Approaches against Multiresistant Superbugs102
Are Quaternary Ammonium Compounds, the Workhorse Disinfectants, Effective against Severe Acute Respiratory Syndrome-Coronavirus-2?91
Comparative Analysis of Primer–Probe Sets for RT-qPCR of COVID-19 Causative Virus (SARS-CoV-2)89
Liposomes for Antibiotic Encapsulation and Delivery83
Comparative Multiplexed Interactomics of SARS-CoV-2 and Homologous Coronavirus Nonstructural Proteins Identifies Unique and Shared Host-Cell Dependencies78
Small-Molecule Inhibitors of the Coronavirus Spike: ACE2 Protein–Protein Interaction as Blockers of Viral Attachment and Entry for SARS-CoV-271
Synthetic Antimicrobial Polymers in Combination Therapy: Tackling Antibiotic Resistance71
Zoliflodacin: An Oral Spiropyrimidinetrione Antibiotic for the Treatment of Neisseria gonorrheae, Including Multi-Drug-Resistant Isolates71
Challenges for Targeting SARS-CoV-2 Proteases as a Therapeutic Strategy for COVID-1967
Boceprevir, Calpain Inhibitors II and XII, and GC-376 Have Broad-Spectrum Antiviral Activity against Coronaviruses67
Electrochemical Diagnostics for Bacterial Infectious Diseases65
Human Cathelicidin Inhibits SARS-CoV-2 Infection: Killing Two Birds with One Stone64
The SARS-CoV-2 Cytopathic Effect Is Blocked by Lysosome Alkalizing Small Molecules57
Effects of Antibiotic Treatment on Gut Microbiota and How to Overcome Its Negative Impacts on Human Health55
Prospecting Human Milk Oligosaccharides as a Defense Against Viral Infections53
The Structure-Based Design of SARS-CoV-2 nsp14 Methyltransferase Ligands Yields Nanomolar Inhibitors53
Clinical and Laboratory Diagnosis of SARS-CoV-2, the Virus Causing COVID-1952
Recognition of Divergent Viral Substrates by the SARS-CoV-2 Main Protease50
Exogenous Nitric Oxide Improves Antibiotic Susceptibility in Resistant Bacteria50
Emerging Vaccine-Breakthrough SARS-CoV-2 Variants47
Two Years into the COVID-19 Pandemic: Lessons Learned45
Reproducible Breath Metabolite Changes in Children with SARS-CoV-2 Infection45
Current Perspective of Antiviral Strategies against COVID-1945
The Antibacterial Research and Development Pipeline Needs Urgent Solutions42
Codelivery of Sustainable Antimicrobial Agents and Platelet-Derived Growth Factor via Biodegradable Nanofibers for Repair of Diabetic Infectious Wounds41
Combined Efficacy of an Antimicrobial Cationic Peptide Polymer with Conventional Antibiotics to Combat Multidrug-Resistant Pathogens41
Old Drugs for a New Virus: Repurposed Approaches for Combating COVID-1939
Plasmodium Kinases as Potential Drug Targets for Malaria: Challenges and Opportunities39
Mucin-Degrading Microbes Release Monosaccharides That Chemoattract Clostridioides difficile and Facilitate Colonization of the Human Intestinal Mucus Layer38
Kanamycin Uptake into Escherichia coli Is Facilitated by OmpF and OmpC Porin Channels Located in the Outer Membrane38
Structure–Activity Relationship Studies of Acetazolamide-Based Carbonic Anhydrase Inhibitors with Activity against Neisseria gonorrhoeae38
Therapeutic Potential of Nitazoxanide: An Appropriate Choice for Repurposing versus SARS-CoV-2?37
COVID-19: Living through Another Pandemic36
Self-Assembly of Antimicrobial Peptoids Impacts Their Biological Effects on ESKAPE Bacterial Pathogens35
Prioritization of Molecular Targets for Antimalarial Drug Discovery34
A Glance at Antimicrobial Strategies to Prevent Catheter-Associated Medical Infections34
Immunogenicity and Protective Efficacy of a Highly Thermotolerant, Trimeric SARS-CoV-2 Receptor Binding Domain Derivative34
JMX0207, a Niclosamide Derivative with Improved Pharmacokinetics, Suppresses Zika Virus Infection Both In Vitro and In Vivo32
Detection, Mapping, and Proteotyping of SARS-CoV-2 Coronavirus with High Resolution Mass Spectrometry32
Plasmodium falciparum Artemisinin Resistance: The Effect of Heme, Protein Damage, and Parasite Cell Stress Response32
Enterovirus D68 Antivirals: Past, Present, and Future32
Structure and Mutations of SARS-CoV-2 Spike Protein: A Focused Overview32
Antibody Affinity Governs the Inhibition of SARS-CoV-2 Spike/ACE2 Binding in Patient Serum31
Heterologous Protein Expression Favors the Formation of Protein Aggregates in Persister and Viable but Nonculturable Bacteria31
Gut Microbiota and Gynecological Cancers: A Summary of Pathogenetic Mechanisms and Future Directions31
HBsAg, Subviral Particles, and Their Clearance in Establishing a Functional Cure of Chronic Hepatitis B Virus Infection31
Preclinical Gold Complexes as Oral Drug Candidates to Treat Leishmaniasis Are Potent Trypanothione Reductase Inhibitors30
Synergistic Effects of Phage–Antibiotic Combinations against Citrobacter amalonaticus30
Structural, Biophysical, and Biochemical Elucidation of the SARS-CoV-2 Nonstructural Protein 3 Macro Domain30
Synergy by Perturbing the Gram-Negative Outer Membrane: Opening the Door for Gram-Positive Specific Antibiotics30
Inhibitors of L-Type Calcium Channels Show Therapeutic Potential for Treating SARS-CoV-2 Infections by Preventing Virus Entry and Spread29
Detection and Quantification of HspX Antigen in Sputum Samples Using Plasmonic Biosensing: Toward a Real Point-of-Care (POC) for Tuberculosis Diagnosis29
ANT2681: SAR Studies Leading to the Identification of a Metallo-β-lactamase Inhibitor with Potential for Clinical Use in Combination with Meropenem for the Treatment of Infections Caused by NDM-Produc29
Quinoline and Quinazoline Derivatives Inhibit Viral RNA Synthesis by SARS-CoV-2 RdRp28
Gallium(III)–Salophen as a Dual Inhibitor of Pseudomonas aeruginosa Heme Sensing and Iron Acquisition28
Targeting Crucial Host Factors of SARS-CoV-227
High-Throughput Screening of an FDA-Approved Drug Library Identifies Inhibitors against Arenaviruses and SARS-CoV-227
Identifying Oxacillinase-48 Carbapenemase Inhibitors Using DNA-Encoded Chemical Libraries27
To Push or To Pull? In a Post-COVID World, Supporting and Incentivizing Antimicrobial Drug Development Must Become a Governmental Priority27
Identification of Cisplatin and Palladium(II) Complexes as Potent Metallo-β-lactamase Inhibitors for Targeting Carbapenem-Resistant Enterobacteriaceae27
Alternatives to Praziquantel for the Prevention and Control of Schistosomiasis27
Nanomaterials: The New Antimicrobial Magic Bullet27
Vancomycin C-Terminus Guanidine Modifications and Further Insights into an Added Mechanism of Action Imparted by a Peripheral Structural Modification27
Local and Sustained Delivery of Rifampicin from a Bioactive Ceramic Carrier Treats Bone Infection in Rat Tibia26
From Antibacterial to Antibiofilm Targeting: An Emerging Paradigm Shift in the Development of Quaternary Ammonium Compounds (QACs)26
Porphyromonas gingivalis Promotes the Proliferation and Migration of Esophageal Squamous Cell Carcinoma through the miR-194/GRHL3/PTEN/Akt Axis26
Innovation in Antimicrobial Resistance: The CARB-X Perspective25
Helicity Modulation Improves the Selectivity of Antimicrobial Peptoids25
Antibiotics Special Issue: Challenges and Opportunities in Antibiotic Discovery and Development25
In Vitro Characterization of ETX1317, a Broad-Spectrum β-Lactamase Inhibitor That Restores and Enhances β-Lactam Activity against Multi-Drug-Resistant Enterobacteriales, Including Carbap25
Compound Uptake into E. coli Can Be Facilitated by N-Alkyl Guanidiniums and Pyridiniums25
Periplasmic Targets for the Development of Effective Antimicrobials against Gram-Negative Bacteria25
Synthesis and Biological Activities of Oxazolidinone Pleuromutilin Derivatives as a Potent Anti-MRSA Agent24
An Updated View of the Trypanosoma cruzi Life Cycle: Intervention Points for an Effective Treatment24
Binding Studies Reveal Phospholipid Specificity and Its Role in the Calcium-Dependent Mechanism of Action of Daptomycin24
Targeting Polyamines Inhibits Coronavirus Infection by Reducing Cellular Attachment and Entry24
Recent Advances in the Development of Semisynthetic Glycopeptide Antibiotics: 2014–202224
Dilipid Ultrashort Tetrabasic Peptidomimetics Potentiate Novobiocin and Rifampicin Against Multidrug-Resistant Gram-Negative Bacteria24
Photodynamic Inactivation of ESKAPE Group Bacterial Pathogens in Planktonic and Biofilm Cultures Using Metallated Porphyrin-Doped Conjugated Polymer Nanoparticles23
Short and Robust Anti-Infective Lipopeptides Engineered Based on the Minimal Antimicrobial Peptide KR12 of Human LL-3723
Unmasking the Amphotericin B Resistance Mechanisms in Candida haemulonii Species Complex23
Design and Evaluation of New Quinazolin-4(3H)-one Derived PqsR Antagonists as Quorum Sensing Quenchers in Pseudomonas aeruginosa23
Peroxide Antimalarial Drugs Target Redox Homeostasis in Plasmodium falciparum Infected Red Blood Cells23
Discovery, Synthesis, and Biological Evaluation of Dunnianol-Based Mannich Bases against Methicillin-Resistant Staphylococcus aureus (MRSA)23
Antiviral Activity of 7-Substituted 7-Deazapurine Ribonucleosides, Monophosphate Prodrugs, and Triphoshates against Emerging RNA Viruses22
Antibiotic Potentiation in Multidrug-Resistant Gram-Negative Pathogenic Bacteria by a Synthetic Peptidomimetic22
Pseudomonas aeruginosa Biofilm Eradication via Nitric Oxide-Releasing Cyclodextrins22
Recent Insights into Emerging Coronavirus: SARS-CoV-222
Emerging Roles of Glycopeptide Antibiotics: Moving beyond Gram-Positive Bacteria21
Diclazuril Inhibits Biofilm Formation and Hemolysis of Staphylococcus aureus21
New Antimicrobial Peptides with Repeating Unit against Multidrug-Resistant Bacteria21
Antibiotic Therapy and the Gut Microbiome: Investigating the Effect of Delivery Route on Gut Pathogens21
Polyethylenimine: An Intranasal Adjuvant for Liposomal Peptide-Based Subunit Vaccine against Group A Streptococcus21
Antibacterial Surfaces with Activity against Antimicrobial Resistant Bacterial Pathogens and Endospores21
Screening a Library of FDA-Approved and Bioactive Compounds for Antiviral Activity against SARS-CoV-221
Development of Advanced Chimeric Endolysin to Control Multidrug-Resistant Staphylococcus aureus through Domain Shuffling21
Gallium Porphyrin and Gallium Nitrate Synergistically Inhibit Mycobacterial Species by Targeting Different Aspects of Iron/Heme Metabolism21
A Marine Antibiotic Kills Multidrug-Resistant Bacteria without Detectable High-Level Resistance20
Lactoferrin: A Critical Mediator of Both Host Immune Response and Antimicrobial Activity in Response to Streptococcal Infections20
Advancement of GyrB Inhibitors for Treatment of Infections Caused by Mycobacterium tuberculosis and Non-tuberculous Mycobacteria20
Disruption of the Plasmodium falciparum Life Cycle through Transcriptional Reprogramming by Inhibitors of Jumonji Demethylases20
Effective Strategy Targeting Polymyxin-Resistant Gram-Negative Pathogens: Polymyxin B in Combination with the Selective Serotonin Reuptake Inhibitor Sertraline20
Unique Cell Surface Mannan of Yeast Pathogen Candida auris with Selective Binding to IgG20
Membrane-Permeable Antibacterial Enzyme against Multidrug-Resistant Acinetobacter baumannii20
Ultradeformable Lipid Vesicles Localize Amphotericin B in the Dermis for the Treatment of Infectious Skin Diseases20
Structure–Activity Relationship Exploration of 3′-Deoxy-7-deazapurine Nucleoside Analogues as Anti-Trypanosoma brucei Agents20
Clinically Relevant Bacterial Outer Membrane Models for Antibiotic Screening Applications20
Ceftazidime–Avibactam Resistance Mutations V240G, D179Y, and D179Y/T243M in KPC-3 β-Lactamase Do Not Alter Cefpodoxime–ETX1317 Susceptibility19
Imaging of Actively Proliferating Bacterial Infections by Targeting the Bacterial Metabolic Footprint with d-[5-11C]-Glutamine19
The SARS-CoV-2 SSHHPS Recognized by the Papain-like Protease19
A Cephalosporin Prochelator Inhibits New Delhi Metallo-β-lactamase 1 without Removing Zinc19
A Microbe-Derived Efflux Pump Inhibitor of the Resistance-Nodulation-Cell Division Protein Restores Antibiotic Susceptibility in Escherichia coli and Pseudomonas aeruginosa19
Inhibition of Human Coronaviruses by Antimalarial Peroxides19
Modeling Enteropathy or Diarrhea with the Top Bacterial and Protozoal Pathogens: Differential Determinants of Outcomes19
Screening an Established Natural Product Library Identifies Secondary Metabolites That Potentiate Conventional Antibiotics19
A Highly Potent SARS-CoV-2 Blocking Lectin Protein19
Altered Gut Microbiome under Antiretroviral Therapy: Impact of Efavirenz and Zidovudine19
Overcoming Planktonic and Intracellular Staphylococcus aureus-Associated Infection with a Cell-Penetrating Peptide-Conjugated Antimicrobial Peptide19
Expanding Bromodomain Targeting into Neglected Parasitic Diseases19
Outer Membranes of Polymyxin-Resistant Acinetobacter baumannii with Phosphoethanolamine-Modified Lipid A and Lipopolysaccharide Loss Display Different Atomic-Scale Interactions with Polymyxins18
Rapid in Vitro Assessment of Clostridioides difficile Inhibition by Probiotics Using Dielectrophoresis to Quantify Cell Structure Alterations18
Investigating β-Lactam Drug Targets in Mycobacterium tuberculosis Using Chemical Probes18
Antimalarial Trioxolanes with Superior Drug-Like Properties and In Vivo Efficacy18
Overcoming Multidrug Resistance and Biofilms of Pseudomonas aeruginosa with a Single Dual-Function Potentiator of β-Lactams18
Overcoming Acquired and Native Macrolide Resistance with Bicarbonate18
A Machine Learning Strategy for Drug Discovery Identifies Anti-Schistosomal Small Molecules18
Recombinant Human Secretory IgA Induces Salmonella Typhimurium Agglutination and Limits Bacterial Invasion into Gut-Associated Lymphoid Tissues18
Biosynthesis, Mechanism of Action, and Inhibition of the Enterotoxin Tilimycin Produced by the Opportunistic Pathogen Klebsiella oxytoca18
Benzimidazole Derivatives Are Potent against Multiple Life Cycle Stages of Plasmodium falciparum Malaria Parasites18
Synthesis of Fusidic Acid Derivatives Yields a Potent Antibiotic with an Improved Resistance Profile18
Structure-Guided Molecular Grafting of a Complex Broadly Neutralizing Viral Epitope18
Protective Liquid Crystal Nanoparticles for Targeted Delivery of PslG: A Biofilm Dispersing Enzyme18
Radiosynthesis and Biodistribution of 18F-Linezolid in Mycobacterium tuberculosis-Infected Mice Using Positron Emission Tomography17
Mechanistic Basis of OXA-48-like β-Lactamases’ Hydrolysis of Carbapenems17
Chagas Disease: Current View of an Ancient and Global Chemotherapy Challenge17
Antiviral Potential of the Antimicrobial Drug Atovaquone against SARS-CoV-2 and Emerging Variants of Concern17
Exploitation of a Klebsiella Bacteriophage Receptor-Binding Protein as a Superior Biorecognition Molecule17
Fluorescent Aminoglycoside Antibiotics and Methods for Accurately Monitoring Uptake by Bacteria17
The Global Antibiotic Research and Development Partnership (GARDP) Not-for-Profit Model of Antibiotic Development17
Cationic Antimicrobial Peptides Are Leading the Way to Combat Oropathogenic Infections17
A Salmochelin S4-Inspired Ciprofloxacin Trojan Horse Conjugate17
Clofazimine Reduces the Survival of Salmonella enterica in Macrophages and Mice17
Combining Colistin and Fluconazole Synergistically Increases Fungal Membrane Permeability and Antifungal Cidality17
Structure–Interaction Relationship of Polymyxins with the Membrane of Human Kidney Proximal Tubular Cells17
Pharmacological Characterization of the Mechanism of Action of R523062, a Promising Antiviral for Enterovirus D6817
How to Stimulate and Facilitate Early Stage Antibiotic Discovery17
Structural Basis of Metallo-β-lactamase Inhibition byN-Sulfamoylpyrrole-2-carboxylates17
A Clerodane Diterpene from Callicarpa americana Resensitizes Methicillin-Resistant Staphylococcus aureus to β-Lactam Antibiotics17
Evaluation of EED Inhibitors as a Class of PRC2-Targeted Small Molecules for HIV Latency Reversal17
Inhibition of Influenza Virus Polymerase by Interfering with Its Protein–Protein Interactions17
Alterations of the Treatment-Naive Gut Microbiome in Newly Diagnosed Hepatitis C Virus Infection17
Discovery of Cephalosporin-3′-Diazeniumdiolates That Show Dual Antibacterial and Antibiofilm Effects against Pseudomonas aeruginosa Clinical Cystic Fibrosis Isolates and Efficacy in a Murine Re17
SaccuFlow: A High-Throughput Analysis Platform to Investigate Bacterial Cell Wall Interactions17
Small Molecule Sensors Targeting the Bacterial Cell Wall17
Early Returns on Small Molecule Therapeutics for SARS-CoV-216
Impact of Glycan Linkage to Staphylococcus aureus Wall Teichoic Acid on Langerin Recognition and Langerhans Cell Activation16
Resistome of Staphylococcus aureus in Response to Human Cathelicidin LL-37 and Its Engineered Antimicrobial Peptides16
Therapeutic and Prophylactic Effect of the Experimental Bacteriophage Treatment to Control Diarrhea Caused by E. coli in Newborn Calves16
Spatially Targeted Proteomics of the Host–Pathogen Interface during Staphylococcal Abscess Formation16
2-Mercaptomethyl Thiazolidines (MMTZs) Inhibit All Metallo-β-Lactamase Classes by Maintaining a Conserved Binding Mode16
Small Molecule Inhibitors of the Bacterioferritin (BfrB)–Ferredoxin (Bfd) Complex Kill Biofilm-Embedded Pseudomonas aeruginosa Cells16
Synthesis, Structure–Activity Relationship, and Mechanistic Studies of Aminoquinazolinones Displaying Antimycobacterial Activity16
Ag@ZnO Nanoparticles Induce Antimicrobial Peptides and Promote Migration and Antibacterial Activity of Keratinocytes16
Mechanistic Duality of Bacterial Efflux Substrates and Inhibitors: Example of Simple Substituted Cinnamoyl and Naphthyl Amides16
Design, Synthesis, and Bioactivity of Cyclic Lipopeptide Antibiotics with Varied Polarity, Hydrophobicity, and Positive Charge Distribution16
Pyochelin Biosynthetic Metabolites Bind Iron and Promote Growth in Pseudomonads Demonstrating Siderophore-like Activity16
Vancomyxins: Vancomycin-Polymyxin Nonapeptide Conjugates That Retain Anti-Gram-Positive Activity with Enhanced Potency against Gram-Negative Strains16
An Antiparasitic Compound from the Medicines for Malaria Venture Pathogen Box Promotes Leishmania Tubulin Polymerization16
PfMFR3: A Multidrug-Resistant Modulator in Plasmodium falciparum16
Selective Permeabilization of Gram-Negative Bacterial Membranes Using Multivalent Peptide Constructs for Antibiotic Sensitization16
Induction of Endogenous Antibody Recruitment to the Surface of the Pathogen Enterococcus faecium16
Feleucin-K3 Analogue with an α-(4-Pentenyl)-Ala Substitution at the Key Site Has More Potent Antimicrobial and Antibiofilm Activities in Vitro and in Vivo16
Analysis of Antimicrobial and Antibiofilm Activity of Human Milk Lactoferrin Compared to Bovine Lactoferrin against Multidrug Resistant and Susceptible Acinetobacter baumannii Clinical Isolates16
Repurposing Nonantifungal Approved Drugs for Synergistic Targeting of Fungal Pathogens15
PEP27-2, a Potent Antimicrobial Cell-Penetrating Peptide, Reduces Skin Abscess Formation during Staphylococcus aureus Infections in Mouse When Used in Combination with Antibiotics15
A Semisynthetic Kanglemycin Shows In Vivo Efficacy against High-Burden Rifampicin Resistant Pathogens15
Aptamers for Viral Detection and Inhibition15
Hyper-Synergistic Antifungal Activity of Rapamycin and Peptide-Like Compounds against Candida albicans Orthogonally via Tor1 Kinase15
Type II Antitoxin HigA Is a Key Virulence Regulator in Pseudomonas aeruginosa15
Discovery of Amphamide, a Drug Candidate for the Second Generation of Polyene Antibiotics15
Quaternary Phosphonium Compounds: An Examination of Non-Nitrogenous Cationic Amphiphiles That Evade Disinfectant Resistance15
Cowpea Mosaic Virus Nanoparticle Vaccine Candidates Displaying Peptide Epitopes Can Neutralize the Severe Acute Respiratory Syndrome Coronavirus15
Small Molecule Carboxylates Inhibit Metallo-β-lactamases and Resensitize Carbapenem-Resistant Bacteria to Meropenem15
Post-translational Succinylation of Mycobacterium tuberculosis Enoyl-CoA Hydratase EchA19 Slows Catalytic Hydration of Cholesterol Catabolite 3-Oxo-chol-4,22-diene-24-oyl-CoA15
Virulence and Adhesion of the Treponema pallidum Nichols Strain Simultaneously Decrease in a Continuous-Infection New Zealand White Rabbit Model15
Antileishmanial Chemotherapy through Clemastine Fumarate Mediated Inhibition of the Leishmania Inositol Phosphorylceramide Synthase15
Plasmodium falciparum Acetyl-CoA Synthetase Is Essential for Parasite Intraerythrocytic Development and Chromatin Modification15
Development of Antibiotics That Dysregulate the Neisserial ClpP Protease15
Conjugation to Enterobactin and Salmochelin S4 Enhances the Antimicrobial Activity and Selectivity of β-Lactam Antibiotics against Nontyphoidal Salmonella15
Progress toward the Development of Glycan-Based Vaccines against Campylobacteriosis15
Metabolic Glycan Labeling-Based Screen to Identify Bacterial Glycosylation Genes15
Virion-Associated Polyamines Transmit with Bunyaviruses to Maintain Infectivity and Promote Entry14
Sodium Copper Chlorophyllin Is Highly Effective against Enterovirus (EV) A71 Infection by Blocking Its Entry into the Host Cell14
Discovery of Prenyltransferase Inhibitors with In Vitro and In Vivo Antibacterial Activity14
Cultivation-Free Typing of Bacteria Using Optical DNA Mapping14
Toward a Stable and Potent Coenzyme A-Targeting Antiplasmodial Agent: Structure–Activity Relationship Studies of N-Phenethyl-α-methyl-pantothenamide14
Sustained Release of a Streptococcus pneumoniae Endolysin from Liposomes for Potential Otitis Media Treatment14
Mycobacterium Lipids Modulate Host Cell Membrane Mechanics, Lipid Diffusivity, and Cytoskeleton in a Virulence-Selective Manner14
Atypically Modified Carbapenem Antibiotics Display Improved Antimycobacterial Activity in the Absence of β-Lactamase Inhibitors14
Characterization of Serine Hydrolases Across Clinical Isolates of Commensal Skin Bacteria Staphylococcus epidermidis Using Activity-Based Protein Profiling14
The Pandemic Response Box─Accelerating Drug Discovery Efforts after Disease Outbreaks14
Differences in Cystic Fibrosis-Associated Burkholderia spp. Bacteria Metabolomes after Exposure to the Antibiotic Trimethoprim14
Structural Basis for Inhibitor Potency and Selectivity of Plasmodium falciparum Phosphatidylinositol 4-Kinase Inhibitors14
Deazapurine Nucleoside Analogues for the Treatment of Trichomonas vaginalis14
Effects of Structurally Different HDAC Inhibitors against Trypanosoma cruzi, Leishmania, and Schistosoma mansoni14
Structural Basis for the Regulation of Biofilm Formation and Iron Uptake in A. baumannii by the Blue-Light-Using Photoreceptor, BlsA14
Antimicrobial Susceptibility Testing of Antimicrobial Peptides Requires New and Standardized Testing Structures14
Potency Increase of Spiroketal Analogs of Membrane Inserting Indolyl Mannich Base Antimycobacterials Is Due to Acquisition of MmpL3 Inhibition14
Targeting a Potential G-Quadruplex Forming Sequence Found in the West Nile Virus Genome by Complementary Gamma-Peptide Nucleic Acid Oligomers14
MicroRNA-18b-5p Downregulation Favors Mycobacterium tuberculosis Clearance in Macrophages via HIF-1α by Promoting an Inflammatory Response14
Synergy of the Polymyxin-Chloramphenicol Combination against New Delhi Metallo-β-Lactamase-Producing Klebsiella pneumoniae Is Predominately Driven by Chloramphenicol14
Intracellular Metal Speciation in Streptococcus sanguinis Establishes SsaACB as Critical for Redox Maintenance13
HIV-1 Integrase Inhibitors with Modifications That Affect Their Potencies against Drug Resistant Integrase Mutants13
Investigational Studies on a Hit Compound Cyclopropane–Carboxylic Acid Derivative Targeting O-Acetylserine Sulfhydrylase as a Colistin Adjuvant13
Rapid Detection of Carbapenemase-Producing Enterobacteriacae Based on Surface-Enhanced Raman Spectroscopy with Gold Nanostars13
Herbicides That Target Acetohydroxyacid Synthase Are Potent Inhibitors of the Growth of Drug-Resistant Candida auris13
No-Observed-Effect Level of Silver Phosphate in Carbonate Apatite Artificial Bone on Initial Bone Regeneration13
Pyronaridine Protects against SARS-CoV-2 Infection in Mouse13
The Nonstructural Protein of Guertu Virus Disrupts Host Defenses by Blocking Antiviral Interferon Induction and Action13
Identification of β-Lactams Active against Mycobacterium tuberculosis by a Consortium of Pharmaceutical Companies and Academic Institutions13
Pharmacokinetic/Pharmacodynamic Determination and Preclinical Pharmacokinetics of the β-Lactamase Inhibitor ETX1317 and Its Orally Available Prodrug ETX028213
Design Guidelines for Cationic Pillar[n]arenes that Prevent Biofilm Formation by Gram-Positive Pathogens13
Influence of Lipophilicity on the Antibacterial Activity of Polymyxin Derivatives and on Their Ability to Act as Potentiators of Rifampicin13
From Magic Bullet to Magic Bomb: Reductive Bioactivation of Antiparasitic Agents13
Repositioning and Characterization of 1-(Pyridin-4-yl)pyrrolidin-2-one Derivatives as Plasmodium Cytoplasmic Prolyl-tRNA Synthetase Inhibitors13
Structure, In Vivo Detection, and Antibacterial Activity of Metabolites of SQ109, an Anti-Infective Drug Candidate13
Alterations to the Cardiac Metabolome Induced by Chronic T. cruzi Infection Relate to the Degree of Cardiac Pathology13
Antibiofilm Activity of Human Milk Oligosaccharides against Multidrug Resistant and Susceptible Isolates of Acinetobacter baumannii13
Exotoxin-Targeted Drug Modalities as Antibiotic Alternatives13
Design, Synthesis, and Biological Evaluation of Light-Activated Antibiotics13
Design of a Sea Snake Antimicrobial Peptide Derivative with Therapeutic Potential against Drug-Resistant Bacterial Infection13
Synthetic Mimics of Native Siderophores Disrupt Iron Trafficking in Acinetobacter baumannii13
Fragment-Based Identification of Ligands for Bromodomain-Containing Factor 3 of Trypanosoma cruzi13
Two-Way Regulation of MmpL3 Expression Identifies and Validates Inhibitors of MmpL3 Function in Mycobacterium tuberculosis13
Real-Time Single-Cell Imaging Reveals Accelerating Lipid Peroxyl Radical Formation in Escherichia coli Triggered by a Fluoroquinolone Antibiotic13
Combining Cell Envelope Stress Reporter Assays in a Screening Approach to Identify BAM Complex Inhibitors13
Drug-Repurposing Screening Identified Tropifexor as a SARS-CoV-2 Papain-like Protease Inhibitor13
Positron Emission Tomography Imaging of Staphylococcus aureus Infection Using a Nitro-Prodrug Analogue of 2-[18F]F-p-Aminobenzoic Acid13
Modular Synthetic Routes to Fluorine-Containing Halogenated Phenazine and Acridine Agents That Induce Rapid Iron Starvation in Methicillin-Resistant Staphylococcus aureus Biofilms13
Essential Bromodomain TcBDF2 as a Drug Target against Chagas Disease13
Structure–Activity Relationship Exploration of NNIBP Tolerant Region I Leads to Potent HIV-1 NNRTIs12
Salicylanilides Reduce SARS-CoV-2 Replication and Suppress Induction of Inflammatory Cytokines in a Rodent Model12
The Acinetobacter baumannii Autotransporter Adhesin Ata Recognizes Host Glycans as High-Affinity Receptors12
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