OOIR: Observatory of International Research

Papers

(The TQCC of npj Microgravity is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Red risks for a journey to the red planet: The highest priority human health risks for a mission to Mars	180
A review of alterations to the brain during spaceflight and the potential relevance to crew in long-duration space exploration	75
Update on the effects of microgravity on the musculoskeletal system	72
Terrestrial health applications of visual assessment technology and machine learning in spaceflight associated neuro-ocular syndrome	51
The effects of microgravity on bone structure and function	49
Key points for the development of antioxidant cocktails to prevent cellular stress and damage caused by reactive oxygen species (ROS) during manned space missions	45
The influence of spaceflight and simulated microgravity on bacterial motility and chemotaxis	41
The effects of real and simulated microgravity on cellular mitochondrial function	39
Gravity sensing in plant and animal cells	38
Macrophages in microgravity: the impact of space on immune cells	37
Trabecular bone organoids: a micron-scale ‘humanised’ prototype designed to study the effects of microgravity and degeneration	37
Planetary extravehicular activity (EVA) risk mitigation strategies for long-duration space missions	30
Estimating medical risk in human spaceflight	30
Capillary flow of liquids in open microchannels: overview and recent advances	29
Effects of spaceflight aboard the International Space Station on mouse estrous cycle and ovarian gene expression	26
Effects of exercise countermeasures on multisystem function in long duration spaceflight astronauts	23
Reviving lower body negative pressure as a countermeasure to prevent pathological vascular and ocular changes in microgravity	23
Low-intensity vibration restores nuclear YAP levels and acute YAP nuclear shuttling in mesenchymal stem cells subjected to simulated microgravity	23
Critical heat flux enhancement in microgravity conditions coupling microstructured surfaces and electrostatic field	22
Regular exercise counteracts circadian shifts in core body temperature during long-duration bed rest	21
Overview of lunar dust toxicity risk	21
Microbial applications for sustainable space exploration beyond low Earth orbit	19
Towards sustainable human space exploration—priorities for radiation research to quantify and mitigate radiation risks	19
Sessile volatile drop evaporation under microgravity	19
Meta-analysis of the space flight and microgravity response of the Arabidopsis plant transcriptome	18

Additive effects of simulated microgravity and ionizing radiation in cell death, induction of ROS and expression of RAC2 in human bronchial epithelial cells	17
Modeled microgravity alters lipopolysaccharide and outer membrane vesicle production of the beneficial symbiont Vibrio fischeri	17
Robot-assisted surgery in space: pros and cons. A review from the surgeon’s point of view	15
3D cell culture using a clinostat reproduces microgravity-induced skin changes	15
Impact of convection on the damping of an oscillating droplet during viscosity measurement using the ISS-EML facility	15
Findings from recent studies by the Japan Aerospace Exploration Agency examining musculoskeletal atrophy in space and on Earth	15
Ocular conditions and injuries, detection and management in spaceflight	14
An advance in transfer line chilldown heat transfer of cryogenic propellants in microgravity using microfilm coating for enabling deep space exploration	14
Six degrees head-down tilt bed rest caused low-grade hemolysis: a prospective randomized clinical trial	13
Opposite response of blood vessels in the retina to 6° head-down tilt and long-duration microgravity	13
Mitigating sarcoplasmic reticulum stress limits disuse-induced muscle loss in hindlimb unloaded mice	13
Mechanism for enhancing the growth of mung bean seedlings under simulated microgravity	13
Demonstration of the effect of stirring on nucleation from experiments on the International Space Station using the ISS-EML facility	13
Human behavior and performance in deep space exploration: next challenges and research gaps	13
A way forward for fundamental physics in space	13
Fundamentals and future applications of electrochemical energy conversion in space	12
Diffusion in liquid mixtures	12
Evaluating the effect of spaceflight on the host–pathogen interaction between human intestinal epithelial cells and Salmonella Typhimurium	12
Is contact-line mobility a material parameter?	12
Bone health in spacefaring rodents and primates: systematic review and meta-analysis	12
Scientific perspectives on lunar exploration in Europe	12
Nitrogen flow boiling and chilldown experiments in microgravity using pulse flow and low-thermally conductive coatings	11
Future space experiment platforms for astrobiology and astrochemistry research	11
Electrolysis in reduced gravitational environments: current research perspectives and future applications	11
Mechanical loading recovers bone but not muscle lost during unloading	11
The ejection of large non-oscillating droplets from a hydrophobic wedge in microgravity	11
Detailed modelling of contact line motion in oscillatory wetting	10
How advances in low-g plumbing enable space exploration	10
Mechanical deconditioning of the heart due to long-term bed rest as observed on seismocardiogram morphology	10
Characterization of gene expression profiles in the mouse brain after 35 days of spaceflight mission	9
Impairment of 7F2 osteoblast function by simulated partial gravity in a Random Positioning Machine	9
Evaluating the lettuce metatranscriptome with MinION sequencing for future spaceflight food production applications	9
Computational modeling of orthostatic intolerance for travel to Mars	9
Oscillations of a soft viscoelastic drop	9
The effect of long-term spaceflight on drug potency and the risk of medication failure	9
Analysis of the effects of spaceflight and local administration of thrombopoietin to a femoral defect injury on distal skeletal sites	9
Human skeletal muscle tissue chip autonomous payload reveals changes in fiber type and metabolic gene expression due to spaceflight	9
Transcriptomic response of bioengineered human cartilage to parabolic flight microgravity is sex-dependent	9
Effects of microgravity exposure and fructo-oligosaccharide ingestion on the proteome of soleus and extensor digitorum longus muscles in developing mice	8
Histone deacetylase HDA-4-mediated epigenetic regulation in space-flown C. elegans	8
The kidney, volume homeostasis and osmoregulation in space: current perspective and knowledge gaps	8
Complex plasma research under microgravity conditions	8
Equivalence of sessile droplet dynamics under periodic and steady electric fields	8
Skeletal muscle gene expression dysregulation in long-term spaceflights and aging is clock-dependent	8
Plant and microbial science and technology as cornerstones to Bioregenerative Life Support Systems in space	8
Next generation of astronauts or ESA astronaut 2.0 concept and spotlight on immunity	7
Single-bubble EHD behavior into water two-phase flow under electric-field stress and gravitational acceleration using PFM	7
Gravitational effects on fibroblasts’ function in relation to wound healing	7
The draining of capillary liquids from containers with interior corners aboard the ISS	7
Testing 3D printed biological platform for advancing simulated microgravity and space mechanobiology research	7

Ocular counter-roll is less affected in experienced versus novice space crew after long-duration spaceflight	7
Enhanced self-renewal of human pluripotent stem cells by simulated microgravity	7
Perfect Crystals: microgravity capillary counterdiffusion crystallization of human manganese superoxide dismutase for neutron crystallography	7
Zero gravity induced by parabolic flight enhances automatic capture and weakens voluntary maintenance of visuospatial attention	7
Microfluidics-integrated spaceflight hardware for measuring muscle strength of Caenorhabditis elegans on the International Space Station	7
A perspective on spaceflight associated neuro-ocular syndrome causation secondary to elevated venous sinus pressure	7
Toward the utilisation of resources in space: knowledge gaps, open questions, and priorities	7
Scaffold-based bone tissue engineering in microgravity: potential, concerns and implications	7
Altered sleep spindles and slow waves during space shuttle missions	7
Ocular complaints and diagnoses in spaceflight	7