npj Parkinsons Disease

Papers
(The TQCC of npj Parkinsons Disease is 13. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-04-01 to 2024-04-01.)
ArticleCitations
Meta-analysis of the Parkinson’s disease gut microbiome suggests alterations linked to intestinal inflammation314
Current and projected future economic burden of Parkinson’s disease in the U.S.260
Characterizing dysbiosis of gut microbiome in PD: evidence for overabundance of opportunistic pathogens137
COVID-19 and possible links with Parkinson’s disease and parkinsonism: from bench to bedside113
Genetic predispositions of Parkinson’s disease revealed in patient-derived brain cells84
Alpha-synuclein research: defining strategic moves in the battle against Parkinson’s disease71
Sex specific cognitive differences in Parkinson disease66
Synergy of pandemics-social isolation is associated with worsened Parkinson severity and quality of life61
Dynamic control of the dopamine transporter in neurotransmission and homeostasis56
The impact of COVID-19 and social distancing on people with Parkinson’s disease: a survey study55
Gastrointestinal involvement in Parkinson’s disease: pathophysiology, diagnosis, and management54
How COVID-19 will boost remote exercise-based treatment in Parkinson’s disease: a narrative review54
Toward therapeutic electrophysiology: beta-band suppression as a biomarker in chronic local field potential recordings51
Genetic and environmental factors in Alzheimer’s and Parkinson’s diseases and promising therapeutic intervention via fecal microbiota transplantation50
Incidence of Parkinson disease in North America49
Neuroimaging evidence of glymphatic system dysfunction in possible REM sleep behavior disorder and Parkinson’s disease47
Is LRRK2 the missing link between inflammatory bowel disease and Parkinson’s disease?46
Neurofilament light chain and α-synuclein RT-QuIC as differential diagnostic biomarkers in parkinsonisms and related syndromes46
Multi-modality machine learning predicting Parkinson’s disease45
Gait speed in clinical and daily living assessments in Parkinson’s disease patients: performance versus capacity44
Subthalamic and pallidal deep brain stimulation for Parkinson’s disease—meta-analysis of outcomes44
Diagnostic value of skin RT-QuIC in Parkinson’s disease: a two-laboratory study42
A postmortem study suggests a revision of the dual-hit hypothesis of Parkinson’s disease42
A systematic review on exercise and training-based interventions for freezing of gait in Parkinson’s disease42
Opportunities and challenges of alpha-synuclein as a potential biomarker for Parkinson’s disease and other synucleinopathies41
Short chain fatty acids-producing and mucin-degrading intestinal bacteria predict the progression of early Parkinson’s disease41
Timing variability and midfrontal ~4 Hz rhythms correlate with cognition in Parkinson’s disease40
Probiotics synergized with conventional regimen in managing Parkinson’s disease39
Enteric α-synuclein impairs intestinal epithelial barrier through caspase-1-inflammasome signaling in Parkinson’s disease before brain pathology37
Plasma-borne indicators of inflammasome activity in Parkinson’s disease patients36
Eight-hours conventional versus adaptive deep brain stimulation of the subthalamic nucleus in Parkinson’s disease34
Mechanisms of peripheral levodopa resistance in Parkinson’s disease33
Stress and mindfulness in Parkinson’s disease – a survey in 5000 patients33
Clinical utility of DaTscan in patients with suspected Parkinsonian syndrome: a systematic review and meta-analysis31
The role of brain perivascular space burden in early-stage Parkinson’s disease31
Oleh Hornykiewicz, a giant in the understanding and treatment of Parkinson disease31
Ex vivo expansion of dysfunctional regulatory T lymphocytes restores suppressive function in Parkinson’s disease31
Reduced astrocytic reactivity in human brains and midbrain organoids with PRKN mutations30
Early constipation predicts faster dementia onset in Parkinson’s disease30
Parkinson’s disease multimodal imaging: F-DOPA PET, neuromelanin-sensitive and quantitative iron-sensitive MRI30
Fine mapping of the HLA locus in Parkinson’s disease in Europeans30
Diurnal modulation of subthalamic beta oscillatory power in Parkinson’s disease patients during deep brain stimulation29
A transcriptome-wide association study identifies susceptibility genes for Parkinson’s disease29
Cognitive function in people with and without freezing of gait in Parkinson’s disease29
Astrocytic atrophy as a pathological feature of Parkinson’s disease with LRRK2 mutation28
Rheumatoid arthritis decreases risk for Parkinson’s disease: a Mendelian randomization study28
Lewy body disease or diseases with Lewy bodies?27
A real-world study of wearable sensors in Parkinson’s disease27
Long-term effect of apomorphine infusion in advanced Parkinson’s disease: a real-life study27
Sex-based differences in the activation of peripheral blood monocytes in early Parkinson disease27
Mining imaging and clinical data with machine learning approaches for the diagnosis and early detection of Parkinson’s disease26
Specific immune status in Parkinson’s disease at different ages of onset26
Mining genetic and transcriptomic data using machine learning approaches in Parkinson’s disease26
Acquired dysregulation of dopamine homeostasis reproduces features of Parkinson’s disease26
Cofilin 1 promotes the pathogenicity and transmission of pathological α-synuclein in mouse models of Parkinson’s disease25
Diffusion along perivascular spaces as marker for impairment of glymphatic system in Parkinson’s disease25
Repetitive transcranial magnetic stimulation improves Parkinson’s freezing of gait via normalizing brain connectivity25
Effects of the agility boot camp with cognitive challenge (ABC-C) exercise program for Parkinson’s disease25
Detection of SARS-CoV-2 viral proteins and genomic sequences in human brainstem nuclei25
Plasma branched-chain and aromatic amino acids correlate with the gut microbiota and severity of Parkinson’s disease25
Subthalamic beta bursts correlate with dopamine-dependent motor symptoms in 106 Parkinson’s patients25
A nationwide study of the incidence, prevalence and mortality of Parkinson’s disease in the Norwegian population25
Multivariate prediction of dementia in Parkinson’s disease24
Multiple comorbid sleep disorders adversely affect quality of life in Parkinson’s disease patients24
Astrogliosis and sexually dimorphic neurodegeneration and microgliosis in the olfactory bulb in Parkinson’s disease23
Parkinson’s disease clinical milestones and mortality23
Multimodal phenotypic axes of Parkinson’s disease23
α-Synuclein aggregation in the olfactory bulb induces olfactory deficits by perturbing granule cells and granular–mitral synaptic transmission23
Prognostic biomarkers of Parkinson’s disease in the Spanish EPIC cohort: a multiplatform metabolomics approach22
Non-motor predictors of 36-month quality of life after subthalamic stimulation in Parkinson disease22
RETRACTED ARTICLE: Non-invasive vagus nerve stimulation improves clinical and molecular biomarkers of Parkinson’s disease in patients with freezing of gait22
Gender gap in deep brain stimulation for Parkinson’s disease22
Reference SVA insertion polymorphisms are associated with Parkinson’s Disease progression and differential gene expression22
Speech-based characterization of dopamine replacement therapy in people with Parkinson’s disease22
Synucleinopathy-associated pathogenesis in Parkinson’s disease and the potential for brain-derived neurotrophic factor22
Potent inhibitors of toxic alpha-synuclein identified via cellular time-resolved FRET biosensors21
Effect of Parkinson’s disease and two therapeutic interventions on muscle activity during walking: a systematic review21
Reduced synaptic activity and dysregulated extracellular matrix pathways in midbrain neurons from Parkinson’s disease patients21
A blinded, controlled trial of objective measurement in Parkinson’s disease21
Irritable bowel syndrome and Parkinson’s disease risk: register-based studies21
Nitrosative stress in Parkinson’s disease21
Glucosylceramide in cerebrospinal fluid of patients with GBA-associated and idiopathic Parkinson’s disease enrolled in PPMI20
“Hot cross bun” is a potential imaging marker for the severity of cerebellar ataxia in MSA-C20
Thalamic morphology predicts the onset of freezing of gait in Parkinson’s disease20
Protection from α-Synuclein induced dopaminergic neurodegeneration by overexpression of the mitochondrial import receptor TOM2020
Lysosomal lipid alterations caused by glucocerebrosidase deficiency promote lysosomal dysfunction, chaperone-mediated-autophagy deficiency, and alpha-synuclein pathology20
Transcriptional analysis of peripheral memory T cells reveals Parkinson’s disease-specific gene signatures20
The potential convergence of NLRP3 inflammasome, potassium, and dopamine mechanisms in Parkinson’s disease19
LRRK2 kinase activity regulates GCase level and enzymatic activity differently depending on cell type in Parkinson’s disease19
Pathways to Parkinson’s disease: a spotlight on 14-3-3 proteins19
Alpha-synuclein oligomers and small nerve fiber pathology in skin are potential biomarkers of Parkinson’s disease18
A review on pathology, mechanism, and therapy for cerebellum and tremor in Parkinson’s disease18
Effect of LRRK2 protein and activity on stimulated cytokines in human monocytes and macrophages18
Insights into the multifaceted role of circular RNAs: implications for Parkinson’s disease pathogenesis and diagnosis18
A systematic review and meta-analysis on effects of aerobic exercise in people with Parkinson’s disease18
Post-GWAS knowledge gap: the how, where, and when18
A six-metabolite panel as potential blood-based biomarkers for Parkinson’s disease18
Distinct patterns of speech disorder in early-onset and late-onset de-novo Parkinson’s disease17
Expediting telehealth use in clinical research studies: recommendations for overcoming barriers in North America17
Oral and gut dysbiosis leads to functional alterations in Parkinson’s disease17
A systematic review and meta-analysis of inflammatory biomarkers in Parkinson’s disease17
Parkinson’s disease patients’ short chain fatty acids production capacity after in vitro fecal fiber fermentation17
Plasma p-tau181, neurofilament light chain and association with cognition in Parkinson’s disease17
Glycation modulates glutamatergic signaling and exacerbates Parkinson’s disease-like phenotypes16
High neutrophil-to-lymphocyte ratio predicts short survival in multiple system atrophy16
Dynamic physiological α-synuclein S129 phosphorylation is driven by neuronal activity16
Akinetic rigid symptoms are associated with decline in a cortical motor network in Parkinson’s disease16
Cerebrospinal fluid monocyte chemoattractant protein 1 correlates with progression of Parkinson’s disease16
DAT and TH expression marks human Parkinson’s disease in peripheral immune cells16
Imaging mass cytometry reveals generalised deficiency in OXPHOS complexes in Parkinson’s disease16
Comparative proteomic analysis highlights metabolic dysfunction in α-synucleinopathy16
Parkinson’s disease-associated, sex-specific changes in DNA methylation at PARK7 (DJ-1), SLC17A6 (VGLUT2), PTPRN2 (IA-2β), and NR4A2 (NURR1) in cortical neurons15
Balance response to levodopa predicts balance improvement after bilateral subthalamic nucleus deep brain stimulation in Parkinson’s disease15
Weeding through the haze: a survey on cannabis use among people living with Parkinson’s disease in the US15
Plasma GFAP in Parkinson’s disease with cognitive impairment and its potential to predict conversion to dementia15
Exosome markers of LRRK2 kinase inhibition15
Gut bacterial tyrosine decarboxylase associates with clinical variables in a longitudinal cohort study of Parkinsons disease15
Predictors of clinically significant quality of life impairment in Parkinson’s disease15
Similarities and differences between nigral and enteric dopaminergic neurons unravel distinctive involvement in Parkinson’s disease15
The CloudUPDRS smartphone software in Parkinson’s study: cross-validation against blinded human raters15
Altered neural cell junctions and ion-channels leading to disrupted neuron communication in Parkinson’s disease15
Using a smartwatch and smartphone to assess early Parkinson’s disease in the WATCH-PD study15
A proteogenomic view of Parkinson’s disease causality and heterogeneity15
Exploring human-genome gut-microbiome interaction in Parkinson’s disease14
α-Synuclein-induced dysregulation of neuronal activity contributes to murine dopamine neuron vulnerability14
Computer vision quantification of whole-body Parkinsonian bradykinesia using a large multi-site population14
Angiotensin type-1 receptor and ACE2 autoantibodies in Parkinson´s disease14
Long-term Parkinson’s disease quality of life after staged DBS: STN vs GPi and first vs second lead14
Peripheral decarboxylase inhibitors paradoxically induce aromatic L-amino acid decarboxylase14
A series of helical α-synuclein fibril polymorphs are populated in the presence of lipid vesicles14
Mitophagy and reactive oxygen species interplay in Parkinson’s disease14
Mutant LRRK2 in lymphocytes regulates neurodegeneration via IL-6 in an inflammatory model of Parkinson’s disease14
Specific gut microbiota alterations in essential tremor and its difference from Parkinson’s disease14
Arm swing responsiveness to dopaminergic medication in Parkinson’s disease depends on task complexity14
Identification and prediction of Parkinson’s disease subtypes and progression using machine learning in two cohorts14
A comparative study of asleep and awake deep brain stimulation robot-assisted surgery for Parkinson’s disease14
Serum lipid profile among sporadic and familial forms of Parkinson’s disease14
A randomized controlled double-blind study of rotigotine on neuropsychiatric symptoms in de novo PD14
Revisiting the specificity and ability of phospho-S129 antibodies to capture alpha-synuclein biochemical and pathological diversity13
Protein aggregation and calcium dysregulation are hallmarks of familial Parkinson’s disease in midbrain dopaminergic neurons13
Cerebrospinal fluid biomarkers in Parkinson’s disease with freezing of gait: an exploratory analysis13
Parkinson’s disease patients benefit from bicycling - a systematic review and meta-analysis13
Axial impairment and falls in Parkinson’s disease: 15 years of subthalamic deep brain stimulation13
Improving estimation of Parkinson’s disease risk—the enhanced PREDICT-PD algorithm13
A systematic review of associations between common SNCA variants and clinical heterogeneity in Parkinson’s disease13
Parkinson’s disease patient-specific neuronal networks carrying the LRRK2 G2019S mutation unveil early functional alterations that predate neurodegeneration13
Association between inflammatory bowel disease and Parkinson’s disease: A Mendelian randomization study13
Biallelic expansion in RFC1 as a rare cause of Parkinson’s disease13
Adverse effects of hypertension, supine hypertension, and perivascular space on cognition and motor function in PD13
Probable REM sleep behavior disorder is associated with longitudinal cortical thinning in Parkinson’s disease13
Altered interhemispheric synchrony in Parkinson’s disease patients with levodopa-induced dyskinesias13
Comprehensive subtyping of Parkinson’s disease patients with similarity fusion: a case study with BioFIND data13
0.031761884689331