Molecular Therapy-Oncolytics

Papers
(The median citation count of Molecular Therapy-Oncolytics is 8. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-03-01 to 2024-03-01.)
ArticleCitations
CXCR1 Expression to Improve Anti-Cancer Efficacy of Intravenously Injected CAR-NK Cells in Mice with Peritoneal Xenografts87
Regulation of Glycolysis by Non-coding RNAs in Cancer: Switching on the Warburg Effect84
B7-H3-Targeted CAR-T Cells Exhibit Potent Antitumor Effects on Hematologic and Solid Tumors67
Targeting YTHDF1 effectively re-sensitizes cisplatin-resistant colon cancer cells by modulating GLS-mediated glutamine metabolism66
Efficacy and Safety of CD28- or 4-1BB-Based CD19 CAR-T Cells in B Cell Acute Lymphoblastic Leukemia65
Molecular profiles of small cell lung cancer subtypes: Therapeutic implications61
Long non-coding RNAs: Biogenesis, functions, and clinical significance in gastric cancer58
Rapidly Switchable Universal CAR-T Cells for Treatment of CD123-Positive Leukemia57
CAR T cell therapy and the tumor microenvironment: Current challenges and opportunities57
Tumor-Secreted Exosomal lncRNA POU3F3 Promotes Cisplatin Resistance in ESCC by Inducing Fibroblast Differentiation into CAFs52
M2 macrophage-derived exosomal microRNA-155-5p promotes the immune escape of colon cancer by downregulating ZC3H12B52
Characterization of the fatty acid metabolism in colorectal cancer to guide clinical therapy48
Carboranes as unique pharmacophores in antitumor medicinal chemistry46
Efficacy of a Third-Generation Oncolytic Herpes Virus G47Δ in Advanced Stage Models of Human Gastric Cancer46
Fascin actin-bundling protein 1 in human cancer: Promising biomarker or therapeutic target?46
Analysis of Lung Adenocarcinoma Subtypes Based on Immune Signatures Identifies Clinical Implications for Cancer Therapy45
Systematic profiling of ferroptosis gene signatures predicts prognostic factors in esophageal squamous cell carcinoma43
ENO1 and Cancer43
Single-cell RNA sequencing in cancer: Applications, advances, and emerging challenges42
In Vitro and MD Simulation Study to Explore Physicochemical Parameters for Antibacterial Peptide to Become Potent Anticancer Peptide42
Natural Killer Cells: Diverse Functions in Tumor Immunity and Defects in Pre-neoplastic and Neoplastic Stages of Tumorigenesis41
Engineering Chimeric Antigen Receptor T Cells against Immune Checkpoint Inhibitors PD-1/PD-L1 for Treating Pancreatic Cancer40
Engineered CAR-T cells targeting TAG-72 and CD47 in ovarian cancer40
Tumor microenvironment and immune-related therapies of head and neck squamous cell carcinoma39
CircRHBDD1 augments metabolic rewiring and restricts immunotherapy efficacy via m6A modification in hepatocellular carcinoma38
Metformin enhances anti-cancer effects of cisplatin in meningioma through AMPK-mTOR signaling pathways37
Tumor immune microenvironment-based classifications of bladder cancer for enhancing the response rate of immunotherapy37
Valeric Acid Suppresses Liver Cancer Development by Acting as a Novel HDAC Inhibitor37
CAR-T Cells Targeting Epstein-Barr Virus gp350 Validated in a Humanized Mouse Model of EBV Infection and Lymphoproliferative Disease37
Route of 41BB/41BBL Costimulation Determines Effector Function of B7-H3-CAR.CD28ζ T Cells36
Viral Delivery of CAR Targets to Solid Tumors Enables Effective Cell Therapy36
Oncolytic herpes virus G47Δ works synergistically with CTLA-4 inhibition via dynamic intratumoral immune modulation36
Chimeric Antigen Receptor T Cell Therapy Targeting ICAM-1 in Gastric Cancer36
The emerging role of off-the-shelf engineered natural killer cells in targeted cancer immunotherapy35
The next wave of cellular immunotherapies in pancreatic cancer35
Mesenchymal Stem Cell-Secreted Exosome Promotes Chemoresistance in Breast Cancer via Enhancing miR-21-5p-Mediated S100A6 Expression34
Comprehensive Analysis of the Expressionand Prognosis for TDO2 in Breast Cancer34
Prognostic Implication of a Metabolism-Associated Gene Signature in Lung Adenocarcinoma34
circRNA circFUT8 Upregulates Krüpple-like Factor 10 to Inhibit the Metastasis of Bladder Cancer via Sponging miR-570-3p34
Novel roles of METTL1/WDR4 in tumor via m7G methylation33
Secretion of bispecific protein of anti-PD-1 fused with TGF-β trap enhances antitumor efficacy of CAR-T cell therapy33
Radiation-Induced DNMT3B Promotes Radioresistance in Nasopharyngeal Carcinoma through Methylation of p53 and p2132
Comparison of Clinically Relevant Oncolytic Virus Platforms for Enhancing T Cell Therapy of Solid Tumors32
Analysis and Augmentation of the Immunologic Bystander Effects of CAR T Cell Therapy in a Syngeneic Mouse Cancer Model32
Inhibition of Autophagy Amplifies Baicalein-Induced Apoptosis in Human Colorectal Cancer32
Angiogenesis-related non-coding RNAs and gastrointestinal cancer32
The m6A-Related mRNA Signature Predicts the Prognosis of Pancreatic Cancer Patients32
Non-coding RNAs and glioblastoma: Insight into their roles in metastasis32
Chromosome Abnormalities: New Insights into Their Clinical Significance in Cancer32
LunX-CAR T Cells as a Targeted Therapy for Non-Small Cell Lung Cancer32
Prognostic and therapeutic TILs of cervical cancer—Current advances and future perspectives31
Electroporation of NKG2D RNA CAR Improves Vγ9Vδ2 T Cell Responses against Human Solid Tumor Xenografts31
m6A methyltransferase METTL3-mediated lncRNA FOXD2-AS1 promotes the tumorigenesis of cervical cancer30
SNHG1 knockdown upregulates miR-376a and downregulates FOXK1/Snail axis to prevent tumor growth and metastasis in HCC30
Exosomal and intracellular miR-320b promotes lymphatic metastasis in esophageal squamous cell carcinoma30
DCLK1 Regulates Tumor Stemness and Cisplatin Resistance in Non-small Cell Lung Cancer via ABCD-Member-430
A New Tool for CRISPR-Cas13a-Based Cancer Gene Therapy29
Efficacy of cancer-specific anti-podoplanin CAR-T cells and oncolytic herpes virus G47Δ combination therapy against glioblastoma29
The antitumor capacity of mesothelin-CAR-T cells in targeting solid tumors in mice29
NK Cells Augment Oncolytic Adenovirus Cytotoxicity in Ovarian Cancer28
BRD4: An emerging prospective therapeutic target in glioma28
microRNA-130b-3p contained in MSC-derived EVs promotes lung cancer progression by regulating the FOXO3/NFE2L2/TXNRD1 axis28
Hypomethylation Causes MIR21 Overexpression in Tumors28
SOX2 Promotes Brain Metastasis of Breast Cancer by Upregulating the Expression of FSCN1 and HBEGF28
Phase I trial of oncolytic adenovirus-mediated cytotoxic and interleukin-12 gene therapy for the treatment of metastatic pancreatic cancer27
Genetic variants in m6A modification core genes are associated with glioma risk in Chinese children27
Annexin A8 regulated by lncRNA-TUG1/miR-140-3p axis promotes bladder cancer progression and metastasis27
CD133 mRNA-Loaded Dendritic Cell Vaccination Abrogates Glioma Stem Cell Propagation in Humanized Glioblastoma Mouse Model27
miR-7 Reduces Breast Cancer Stem Cell Metastasis via Inhibiting RELA to Decrease ESAM Expression27
m6A demethylase FTO induces NELL2 expression by inhibiting E2F1 m6A modification leading to metastasis of non-small cell lung cancer26
A PTAL-miR-101-FN1 Axis Promotes EMT and Invasion-Metastasis in Serous Ovarian Cancer26
Landscape and perspectives of macrophage -targeted cancer therapy in clinical trials26
miR-16-5p/PDK4-Mediated Metabolic Reprogramming Is Involved in Chemoresistance of Cervical Cancer26
Ectopic Expression of miR-532-3p Suppresses Bone Metastasis of Prostate Cancer Cells via Inactivating NF-κB Signaling25
Insulin and Metformin Control Cell Proliferation by Regulating TDG-Mediated DNA Demethylation in Liver and Breast Cancer Cells25
Defueling the cancer: ATP synthase as an emerging target in cancer therapy25
Self-Assembled Multivalent Aptamer Nanoparticles with Potential CAR-like Characteristics Could Activate T Cells and Inhibit Melanoma Growth25
Systematic review of the immunological landscape of Wilms tumors25
Natural killer cells and immune-checkpoint inhibitor therapy: Current knowledge and new challenges25
Protein Palmitoylation Regulates Cell Survival by Modulating XBP1 Activity in Glioblastoma Multiforme24
MGP Promotes Colon Cancer Proliferation by Activating the NF-κB Pathway through Upregulation of the Calcium Signaling Pathway24
RETRACTED: miR-140-3p Inhibits Cutaneous Melanoma Progression by Disrupting AKT/p70S6K and JNK Pathways through ABHD224
lncRNA DUXAP8 Facilitates Multiple Malignant Phenotypes and Resistance to PARP Inhibitor in HCC via Upregulating FOXM124
PSMA-Directed CAR T Cells Combined with Low-Dose Docetaxel Treatment Induce Tumor Regression in a Prostate Cancer Xenograft Model24
Ginkgolic Acid, a SUMO-1 Inhibitor, Inhibits the Progression of Oral Squamous Cell Carcinoma by Alleviating SUMOylation of SMAD424
Advances and new frontiers for immunotherapy in colorectal cancer: Setting the stage for neoadjuvant success?24
Characterization of a novel OX40 ligand and CD40 ligand-expressing oncolytic adenovirus used in the PeptiCRAd cancer vaccine platform24
Oncolytic Virus-Mediated Targeting of the ERK Signaling Pathway Inhibits Invasive Propensity in Human Pancreatic Cancer23
Systemic delivery of TNF-armed myxoma virus plus immune checkpoint inhibitor eliminates lung metastatic mouse osteosarcoma23
Association of IDH mutation and 1p19q co-deletion with tumor immune microenvironment in lower-grade glioma23
Generation of a Tumor-Specific Chemokine Gradient Using Oncolytic Vesicular Stomatitis Virus Encoding CXCL923
miR-489-3p/SIX1 Axis Regulates Melanoma Proliferation and Glycolytic Potential23
Regulatory role and mechanism of m6A RNA modification in human metabolic diseases22
Inhibition of USP14 Deubiquitinating Activity as a Potential Therapy for Tumors with p53 Deficiency22
Exosome-mediated transfer of MIF confers temozolomide resistance by regulating TIMP3/PI3K/AKT axis in gliomas22
Monocarboxylate Transporter 4 Is a Therapeutic Target in Non-small Cell Lung Cancer with Aerobic Glycolysis Preference22
MMP25-AS1/hsa-miR-10a-5p/SERPINE1 axis as a novel prognostic biomarker associated with immune cell infiltration in KIRC22
Addition of BTK inhibitor orelabrutinib to rituximab improved anti-tumor effects in B cell lymphoma22
Single-cell RNA-sequencing analyses identify heterogeneity of CD8+ T cell subpopulations and novel therapy targets in melanoma22
Histone Deacetylase Inhibitor Sensitizes ERCC1-High Non-small-Cell Lung Cancer Cells to Cisplatin via Regulating miR-14922
In Situ Therapeutic Cancer Vaccination with an Oncolytic Virus Expressing Membrane-Tethered IL-222
Tartrate-Resistant Acid Phosphatase 5/ACP5 Interacts with p53 to Control the Expression of SMAD3 in Lung Adenocarcinoma21
WTAP Gene Variants Confer Hepatoblastoma Susceptibility: A Seven-Center Case-Control Study21
Exosomal miR-205-5p enhances angiogenesis and nasopharyngeal carcinoma metastasis by targeting desmocollin-221
A novel TanCAR targeting IL13Rα2 and EphA2 for enhanced glioblastoma therapy21
The PERK Inhibitor GSK2606414 Enhances Reovirus Infection in Head and Neck Squamous Cell Carcinoma via an ATF4-Dependent Mechanism21
Neoadjuvant Use of Oncolytic Herpes Virus G47Δ Enhances the Antitumor Efficacy of Radiofrequency Ablation21
Mithramycin A and Mithralog EC-8042 Inhibit SETDB1 Expression and Its Oncogenic Activity in Malignant Melanoma20
Scutellarin resensitizes oxaliplatin-resistant colorectal cancer cells to oxaliplatin treatment through inhibition of PKM220
The lncRNA DLGAP1-AS1/miR-149-5p/TGFB2 axis contributes to colorectal cancer progression and 5-FU resistance by regulating smad2 pathway20
Inhibition of tumor invasion and metastasis by targeting TGF-β-Smad-MMP2 pathway with Asiatic acid and Naringenin20
Targeting EGFR sensitizes 5-Fu-resistant colon cancer cells through modification of the lncRNA-FGD5-AS1-miR-330-3p-Hexokinase 2 axis20
Retargeted and Multi-cytokine-Armed Herpes Virus Is a Potent Cancer Endovaccine for Local and Systemic Anti-tumor Treatment20
Irisin Is a Positive Regulator for Ferroptosis in Pancreatic Cancer20
LRPPRC regulates metastasis and glycolysis by modulating autophagy and the ROS/HIF1-α pathway in retinoblastoma20
Highly efficient PD-1-targeted CRISPR-Cas9 for tumor-infiltrating lymphocyte-based adoptive T cell therapy19
The PABPC5/HCG15/ZNF331 Feedback Loop Regulates Vasculogenic Mimicry of Glioma via STAU1-Mediated mRNA Decay19
Molecular Targeting of Cancer-Associated PCNA Interactions in Pancreatic Ductal Adenocarcinoma Using a Cell-Penetrating Peptide19
Systemic immunity upon local oncolytic virotherapy armed with immunostimulatory genes may be supported by tumor-derived exosomes19
A brief review of reporter gene imaging in oncolytic virotherapy and gene therapy19
Adoptive T cell immunotherapy for medullary thyroid carcinoma targeting GDNF family receptor alpha 419
Characterization of hypoxia response patterns identified prognosis and immunotherapy response in bladder cancer19
A Cereblon Modulator CC-885 Induces CRBN- and p97-Dependent PLK1 Degradation and Synergizes with Volasertib to Suppress Lung Cancer19
The long non-coding RNA SNHG4/microRNA-let-7e/KDM3A/p21 pathway is involved in the development of non-small cell lung cancer19
miR-19a/b promote EMT and proliferation in glioma cells via SEPT7-AKT-NF-κB pathway18
Boosting Replication and Penetration of Oncolytic Adenovirus by Paclitaxel Eradicate Peritoneal Metastasis of Gastric Cancer18
lncRNA MIR503HG inhibits cell proliferation and promotes apoptosis in TNBC cells via the miR-224-5p/HOXA9 axis18
METTL3 increases cisplatin chemosensitivity of cervical cancer cells via downregulation of the activity of RAGE18
Current strategies in engaging oncolytic viruses with antitumor immunity18
A Novel Antitumor Strategy: Simultaneously Inhibiting Angiogenesis and Complement by Targeting VEGFA/PIGF and C3b/C4b18
Classification of pediatric gliomas based on immunological profiling: Implications for immunotherapy strategies18
Myxoma Virus-Loaded Mesenchymal Stem Cells in Experimental Oncolytic Therapy of Murine Pulmonary Melanoma18
Antitumor Activity In Vivo and Vitro of New Chiral Derivatives of Baicalin and Induced Apoptosis via the PI3K/Akt Signaling Pathway17
Overexpression of YBX1 Promotes Pancreatic Ductal Adenocarcinoma Growth via the GSK3B/Cyclin D1/Cyclin E1 Pathway17
Resveratrol Inhibits the Tumorigenesis of Follicular Thyroid Cancer via ST6GAL2-Regulated Activation of the Hippo Signaling Pathway17
Oncolytic reovirus-mediated recruitment of early innate immune responses reverses immunotherapy resistance in prostate tumors17
Efferocytosis and Its Associated Cytokines: A Light on Non-tumor and Tumor Diseases?17
miR-324-5p Contributes to Cell Proliferation and Apoptosis in Pancreatic Cancer by Targeting KLF317
Gene Silencing of Transferrin-1 Receptor as a Potential Therapeutic Target for Human Follicular and Anaplastic Thyroid Cancer17
CXCR5 guides migration and tumor eradication of anti-EGFR chimeric antigen receptor T cells17
Lactate Dehydrogenase A Depletion Alters MyC-CaP Tumor Metabolism, Microenvironment, and CAR T Cell Therapy17
Efficacy and safety of a third-generation oncolytic herpes virus G47Δ in models of human esophageal carcinoma17
lncRNA SNHG26 promoted the growth, metastasis, and cisplatin resistance of tongue squamous cell carcinoma through PGK1/Akt/mTOR signal pathway16
Long Non-coding RNA EPIC1 Promotes Cell Proliferation and Motility and Drug Resistance in Glioma16
Imaging CAR T-cell kinetics in solid tumors: Translational implications16
The role of long non-coding RNAs in the pathogenesis of head and neck squamous cell carcinoma16
Transcriptional landscape associated with TNBC resistance to neoadjuvant chemotherapy revealed by single-cell RNA-seq16
Therapeutic potential of IBP as an autophagy inducer for treating lung cancer via blocking PAK1/Akt/mTOR signaling16
Extending traditional antibody therapies: Novel discoveries in immunotherapy and clinical applications16
MicroRNA Modification of Coxsackievirus B3 Decreases Its Toxicity, while Retaining Oncolytic Potency against Lung Cancer16
Wnt7a Counteracts Cancer Cachexia16
Oncolytic Zika virus promotes intratumoral T cell infiltration and improves immunotherapy efficacy in glioblastoma16
Progress and application of circulating tumor cells in non-small cell lung cancer16
miR-155 Accelerates the Growth of Human Liver Cancer Cells by Activating CDK2 via Targeting H3F3A16
Exosomal circSHKBP1 participates in non-small cell lung cancer progression through PKM2-mediated glycolysis16
Tumor-derived exosomal microRNA-7-5p enhanced by verbascoside inhibits biological behaviors of glioblastoma in vitro and in vivo16
Differential Expression Profile of miR-27b, miR-29a, and miR-155 in Chronic Lymphocytic Leukemia and Breast Cancer Patients16
Development of non-viral, ligand-dependent, EPHB4-specific chimeric antigen receptor T cells for treatment of rhabdomyosarcoma15
Breast cancer tumor microenvironment affects Treg/IL-17-producing Treg/Th17 cell axis: Molecular and therapeutic perspectives15
Metformin inhibits gastric cancer cell proliferation by regulation of a novel Loc100506691-CHAC1 axis15
Circular RNAs act as regulators of autophagy in cancer15
Circular RNA circRAB31 acts as a miR-885-5p sponge to suppress gastric cancer progression via the PTEN/PI3K/AKT pathway15
Improving the Efficacy of EGFR Inhibitors by Topical Treatment of Cutaneous Squamous Cell Carcinoma with miR-634 Ointment15
oHSV2 Can Target Murine Colon Carcinoma by Altering the Immune Status of the Tumor Microenvironment and Inducing Antitumor Immunity15
Intracranial delivery of synthetic mRNA to suppress glioblastoma15
A novel PD-L1-targeted shark VNAR single-domain-based CAR-T cell strategy for treating breast cancer and liver cancer15
Circular RNA SERPINE2 promotes development of glioblastoma by regulating the miR-361-3p/miR-324-5p/BCL2 signaling pathway15
GPR50 Promotes Hepatocellular Carcinoma Progression via the Notch Signaling Pathway through Direct Interaction with ADAM1715
Doxorubicin Conjugation to Reovirus Improves Oncolytic Efficacy in Triple-Negative Breast Cancer15
AXL receptor is required for Zika virus strain MR-766 infection in human glioblastoma cell lines15
Design of an Interferon-Resistant Oncolytic HSV-1 Incorporating Redundant Safety Modalities for Improved Tolerability15
Neural Stem Cells Improve the Delivery of Oncolytic Chimeric Orthopoxvirus in a Metastatic Ovarian Cancer Model15
Preclinical Evaluation of the Oncolytic Vaccinia Virus TG6002 by Translational Research on Canine Breast Cancer15
Efficient antitumor effects of a novel oncolytic adenovirus fully composed of species B adenovirus serotype 3515
Upregulated CBX8 Promotes Cancer Metastasis via the WNK2/MMP2 Pathway15
Recombinant SLAMblind Measles Virus Is a Promising Candidate for Nectin-4-Positive Triple Negative Breast Cancer Therapy14
UXT, a novel DNMT3b-binding protein, promotes breast cancer progression via negatively modulating lncRNA MEG3/p53 axis14
IFN-I-tolerant oncolytic Semliki Forest virus in combination with anti-PD1 enhances T cell response against mouse glioma14
Non-signaling Chimeric Antigen Receptors Enhance Antigen-Directed Killing by γδ T Cells in Contrast to αβ T Cells14
USMB-shMincle: a virus-free gene therapy for blocking M1/M2 polarization of tumor-associated macrophages14
CRISPR-Cas knockout of miR21 reduces glioma growth14
miR-155 Overexpression in OT-1 CD8+ T Cells Improves Anti-Tumor Activity against Low-Affinity Tumor Antigen14
A Screened GPR1 Peptide Exerts Antitumor Effects on Triple-Negative Breast Cancer14
Silencing ZIC2 abrogates tumorigenesis and anoikis resistance of non-small cell lung cancer cells by inhibiting Src/FAK signaling13
Ablation of Stromal Cells with a Targeted Proapoptotic Peptide Suppresses Cancer Chemotherapy Resistance and Metastasis13
In vivo CART cell imaging: Paving the way for success in CART cell therapy13
Applications of nuclear-based imaging in gene and cell therapy: Probe considerations13
MicroRNA-sensitive oncolytic measles virus for chemovirotherapy of pancreatic cancer13
Oncolytic herpes virus G47Δ injected into tongue cancer swiftly traffics in lymphatics and suppresses metastasis13
Integrated analysis reveals the molecular features of fibrosis in triple-negative breast cancer13
Sindbis Virus with Anti-OX40 Overcomes the Immunosuppressive Tumor Microenvironment of Low-Immunogenic Tumors13
LukS-PV Inhibits Hepatocellular Carcinoma Progression by Downregulating HDAC2 Expression13
DNA-methylation-induced silencing of DIO3OS drives non-small cell lung cancer progression via activating hnRNPK-MYC-CDC25A axis13
Long non-coding RNAs and circular RNAs in tumor angiogenesis: From mechanisms to clinical significance13
Oncolytic adenovirus-mediated expression of decorin facilitates CAIX-targeting CAR-T therapy against renal cell carcinoma13
R-2HG downregulates ERα to inhibit cholangiocarcinoma via the FTO/m6A-methylated ERα/miR16-5p/YAP1 signal pathway13
miR-124 Intensified Oxaliplatin-Based Chemotherapy by Targeting CAPN2 in Colorectal Cancer13
Arming HSV-Based Oncolytic Viruses with the Ability to Redirect the Host’s Innate Antiviral Immunity to Attack Tumor Cells13
A PD1 targeted nano-delivery system based on epigenetic alterations of T cell responses in the treatment of gastric cancer13
Fluorescent imaging for cancer therapy and cancer gene therapy12
miR-15a and miR-15b modulate natural killer and CD8+T-cell activation and anti-tumor immune response by targeting PD-L1 in neuroblastoma12
Nucleic acids and proteins carried by exosomes of different origins as potential biomarkers for gynecologic cancers12
Dual Inhibition of MAPK and JAK2/STAT3 Pathways Is Critical for the Treatment of BRAF Mutant Melanoma12
Elimination of MYCN-Amplified Neuroblastoma Cells by Telomerase-Targeted Oncolytic Virus via MYCN Suppression12
Cetuximab-Triptolide Conjugate Suppresses the Growth of EGFR-Overexpressing Lung Cancers through Targeting RNA Polymerase II12
Oncolytic virus-mediated p53 overexpression promotes immunogenic cell death and efficacy of PD-1 blockade in pancreatic cancer12
The Role of a Proprotein Convertase Inhibitor in Reactivation of Tumor-Associated Macrophages and Inhibition of Glioma Growth12
Inhibition of Cholesterol Esterification Enzyme Enhances the Potency of Human Chimeric Antigen Receptor T Cells against Pancreatic Carcinoma12
Narciclasine targets STAT3 via distinct mechanisms in tamoxifen-resistant breast cancer cells12
Combining vanadyl sulfate with Newcastle disease virus potentiates rapid innate immune-mediated regression with curative potential in murine cancer models12
Poly(beta-amino ester) nanoparticles enable tumor-specific TRAIL secretion and a bystander effect to treat liver cancer12
Comprehensive landscape of tRNA-derived fragments in lung cancer12
Feasibility study of a novel preparation strategy for anti-CD7 CAR-T cells with a recombinant anti-CD7 blocking antibody12
CCL18 promotes breast cancer progression by exosomal miR-760 activation of ARF6/Src/PI3K/Akt pathway12
LGR6 Promotes Tumor Proliferation and Metastasis through Wnt/β-Catenin Signaling in Triple-Negative Breast Cancer12
Anti-CAIX BBζ CAR4/8 T cells exhibit superior efficacy in a ccRCC mouse model12
A Triple-Regulated Oncolytic Adenovirus Carrying MicroRNA-143 Exhibits Potent Antitumor Efficacy in Colorectal Cancer12
Identification of the Combinatorial Effect of miRNA Family Regulatory Network in Different Growth Patterns of GC12
Hyaluronidase expression within tumors increases virotherapy efficacy and T cell accumulation12
An effective therapeutic regime for treatment of glioma using oncolytic vaccinia virus expressing IL-21 in combination with immune checkpoint inhibition12
CD47-targeted cancer immunogene therapy: Secreted SIRPα-Fc fusion protein eradicates tumors by macrophage and NK cell activation12
Noncoding RNA-mediated macrophage and cancer cell crosstalk in hepatocellular carcinoma12
Combination microRNA-based cellular reprogramming with paclitaxel enhances therapeutic efficacy in a relapsed and multidrug-resistant model of epithelial ovarian cancer11
Superior infectivity of the fiber chimeric oncolytic adenoviruses Ad5/35 and Ad5/3 over Ad5-delta-24-RGD in primary glioma cultures11
Non-coding RNAs and glioma: Focus on cancer stem cells11
Overexpression of miR-382 Sensitizes Hepatocellular Carcinoma Cells to γδ T Cells by Inhibiting the Expression of c-FLIP11
Combination of a STAT3 inhibitor with anti-PD-1 immunotherapy is an effective treatment regimen for a vemurafenib-resistant melanoma11
Non-coding RNAs in melanoma: Biological functions and potential clinical applications11
Introducing a new reporter gene, membrane-anchored Cypridina luciferase, for multiplex bioluminescence imaging11
RBFOX1 Regulates the Permeability of the Blood-Tumor Barrier via the LINC00673/MAFF Pathway11
Tumor Control by Cytomegalovirus: A Door Open for Oncolytic Virotherapy?11
Upregulation of endogenous TRAIL-elicited apoptosis is essential for metformin-mediated antitumor activity against TNBC and NSCLC11
Development of STEAP1 targeting chimeric antigen receptor for adoptive cell therapy against cancer11
Intraperitoneal oncolytic virotherapy for patients with malignant ascites: Characterization of clinical efficacy and antitumor immune response11
Gene knock-out chain reaction enables high disruption efficiency of HPV18 E6/E7 genes in cervical cancer cells11
Novel two-chain structure utilizing KIRS2/DAP12 domain improves the safety and efficacy of CAR-T cells in adults with r/r B-ALL11
Vorolanib, a novel tyrosine receptor kinase receptor inhibitor with potent preclinical anti-angiogenic and anti-tumor activity11
Upregulation of deubiquitinase USP7 by transcription factor FOXO6 promotes EC progression via targeting the JMJD3/CLU axis10
Selective sodium iodide symporter (NIS) gene therapy of glioblastoma mediated by EGFR-targeted lipopolyplexes10
Inhibition of MEK-ERK pathway enhances oncolytic vaccinia virus replication in doxorubicin-resistant ovarian cancer10
Oncolytic Activity of Targeted Picornaviruses Formulated as Synthetic Infectious RNA10
G Protein-Coupled Receptor GPR87 Promotes the Expansion of PDA Stem Cells through Activating JAK2/STAT310
Involvement of actin cytoskeletal modifications in the inhibition of triple-negative breast cancer growth and metastasis by nimbolide10
RUNX1/EGFR pathway contributes to STAT3 activation and tumor growth caused by hyperactivated mTORC110
Multiple targeted self-emulsifying compound RGO reveals obvious anti-tumor potential in hepatocellular carcinoma10
Tmub1 Suppresses Hepatocellular Carcinoma by Promoting the Ubiquitination of ΔNp63 Isoforms10
Quantitative proteomics characterization of cancer biomarkers and treatment10
hsa_circ_0085539 Promotes Osteosarcoma Progression by Regulating miR-526b-5p and SERP110
PROTACs in gastrointestinal cancers10
A Small Molecule Inhibitor, OGP46, Is Effective against Imatinib-Resistant BCR-ABL Mutations via the BCR-ABL/JAK-STAT Pathway10
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