Molecular Therapy-Oncolytics

Papers
(The median citation count of Molecular Therapy-Oncolytics is 8. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)
ArticleCitations
CAR T cell therapy and the tumor microenvironment: Current challenges and opportunities98
Regulation of Glycolysis by Non-coding RNAs in Cancer: Switching on the Warburg Effect93
Targeting YTHDF1 effectively re-sensitizes cisplatin-resistant colon cancer cells by modulating GLS-mediated glutamine metabolism89
Long non-coding RNAs: Biogenesis, functions, and clinical significance in gastric cancer77
ENO1 and Cancer76
Molecular profiles of small cell lung cancer subtypes: Therapeutic implications70
M2 macrophage-derived exosomal microRNA-155-5p promotes the immune escape of colon cancer by downregulating ZC3H12B62
Carboranes as unique pharmacophores in antitumor medicinal chemistry61
Characterization of the fatty acid metabolism in colorectal cancer to guide clinical therapy60
Fascin actin-bundling protein 1 in human cancer: Promising biomarker or therapeutic target?55
Engineered CAR-T cells targeting TAG-72 and CD47 in ovarian cancer52
The next wave of cellular immunotherapies in pancreatic cancer52
CircRHBDD1 augments metabolic rewiring and restricts immunotherapy efficacy via m6A modification in hepatocellular carcinoma51
Single-cell RNA sequencing in cancer: Applications, advances, and emerging challenges51
Mesenchymal Stem Cell-Secreted Exosome Promotes Chemoresistance in Breast Cancer via Enhancing miR-21-5p-Mediated S100A6 Expression48
Systematic profiling of ferroptosis gene signatures predicts prognostic factors in esophageal squamous cell carcinoma46
Valeric Acid Suppresses Liver Cancer Development by Acting as a Novel HDAC Inhibitor45
Tumor microenvironment and immune-related therapies of head and neck squamous cell carcinoma45
Oncolytic herpes virus G47Δ works synergistically with CTLA-4 inhibition via dynamic intratumoral immune modulation44
The emerging role of off-the-shelf engineered natural killer cells in targeted cancer immunotherapy44
Tumor immune microenvironment-based classifications of bladder cancer for enhancing the response rate of immunotherapy44
Novel roles of METTL1/WDR4 in tumor via m7G methylation42
Exosomal and intracellular miR-320b promotes lymphatic metastasis in esophageal squamous cell carcinoma41
Secretion of bispecific protein of anti-PD-1 fused with TGF-β trap enhances antitumor efficacy of CAR-T cell therapy41
Metformin enhances anti-cancer effects of cisplatin in meningioma through AMPK-mTOR signaling pathways41
Prognostic and therapeutic TILs of cervical cancer—Current advances and future perspectives39
Efficacy of cancer-specific anti-podoplanin CAR-T cells and oncolytic herpes virus G47Δ combination therapy against glioblastoma38
Non-coding RNAs and glioblastoma: Insight into their roles in metastasis38
Landscape and perspectives of macrophage -targeted cancer therapy in clinical trials38
Prognostic Implication of a Metabolism-Associated Gene Signature in Lung Adenocarcinoma36
Defueling the cancer: ATP synthase as an emerging target in cancer therapy36
A New Tool for CRISPR-Cas13a-Based Cancer Gene Therapy35
Inhibition of Autophagy Amplifies Baicalein-Induced Apoptosis in Human Colorectal Cancer35
Phase I trial of oncolytic adenovirus-mediated cytotoxic and interleukin-12 gene therapy for the treatment of metastatic pancreatic cancer35
Angiogenesis-related non-coding RNAs and gastrointestinal cancer35
The antitumor capacity of mesothelin-CAR-T cells in targeting solid tumors in mice35
m6A methyltransferase METTL3-mediated lncRNA FOXD2-AS1 promotes the tumorigenesis of cervical cancer33
SNHG1 knockdown upregulates miR-376a and downregulates FOXK1/Snail axis to prevent tumor growth and metastasis in HCC33
Regulatory role and mechanism of m6A RNA modification in human metabolic diseases33
Inhibition of tumor invasion and metastasis by targeting TGF-β-Smad-MMP2 pathway with Asiatic acid and Naringenin32
m6A demethylase FTO induces NELL2 expression by inhibiting E2F1 m6A modification leading to metastasis of non-small cell lung cancer31
A novel TanCAR targeting IL13Rα2 and EphA2 for enhanced glioblastoma therapy31
BRD4: An emerging prospective therapeutic target in glioma31
Genetic variants in m6A modification core genes are associated with glioma risk in Chinese children30
microRNA-130b-3p contained in MSC-derived EVs promotes lung cancer progression by regulating the FOXO3/NFE2L2/TXNRD1 axis30
Annexin A8 regulated by lncRNA-TUG1/miR-140-3p axis promotes bladder cancer progression and metastasis30
Characterization of a novel OX40 ligand and CD40 ligand-expressing oncolytic adenovirus used in the PeptiCRAd cancer vaccine platform29
Exosome-mediated transfer of MIF confers temozolomide resistance by regulating TIMP3/PI3K/AKT axis in gliomas29
Exosomal circSHKBP1 participates in non-small cell lung cancer progression through PKM2-mediated glycolysis28
Systematic review of the immunological landscape of Wilms tumors28
Natural killer cells and immune-checkpoint inhibitor therapy: Current knowledge and new challenges28
MMP25-AS1/hsa-miR-10a-5p/SERPINE1 axis as a novel prognostic biomarker associated with immune cell infiltration in KIRC28
Classification of pediatric gliomas based on immunological profiling: Implications for immunotherapy strategies27
Single-cell RNA-sequencing analyses identify heterogeneity of CD8+ T cell subpopulations and novel therapy targets in melanoma27
Scutellarin resensitizes oxaliplatin-resistant colorectal cancer cells to oxaliplatin treatment through inhibition of PKM227
Targeting EGFR sensitizes 5-Fu-resistant colon cancer cells through modification of the lncRNA-FGD5-AS1-miR-330-3p-Hexokinase 2 axis27
Highly efficient PD-1-targeted CRISPR-Cas9 for tumor-infiltrating lymphocyte-based adoptive T cell therapy26
Systemic delivery of TNF-armed myxoma virus plus immune checkpoint inhibitor eliminates lung metastatic mouse osteosarcoma25
Association of IDH mutation and 1p19q co-deletion with tumor immune microenvironment in lower-grade glioma25
Advances and new frontiers for immunotherapy in colorectal cancer: Setting the stage for neoadjuvant success?25
Addition of BTK inhibitor orelabrutinib to rituximab improved anti-tumor effects in B cell lymphoma25
Systemic immunity upon local oncolytic virotherapy armed with immunostimulatory genes may be supported by tumor-derived exosomes25
lncRNA DUXAP8 Facilitates Multiple Malignant Phenotypes and Resistance to PARP Inhibitor in HCC via Upregulating FOXM124
Oncolytic virus-mediated p53 overexpression promotes immunogenic cell death and efficacy of PD-1 blockade in pancreatic cancer24
Exosomal miR-205-5p enhances angiogenesis and nasopharyngeal carcinoma metastasis by targeting desmocollin-224
Adoptive T cell immunotherapy for medullary thyroid carcinoma targeting GDNF family receptor alpha 424
The lncRNA DLGAP1-AS1/miR-149-5p/TGFB2 axis contributes to colorectal cancer progression and 5-FU resistance by regulating smad2 pathway23
Retargeted and Multi-cytokine-Armed Herpes Virus Is a Potent Cancer Endovaccine for Local and Systemic Anti-tumor Treatment23
Antitumor Activity In Vivo and Vitro of New Chiral Derivatives of Baicalin and Induced Apoptosis via the PI3K/Akt Signaling Pathway22
Imaging CAR T-cell kinetics in solid tumors: Translational implications22
Characterization of hypoxia response patterns identified prognosis and immunotherapy response in bladder cancer22
The long non-coding RNA SNHG4/microRNA-let-7e/KDM3A/p21 pathway is involved in the development of non-small cell lung cancer22
Current strategies in engaging oncolytic viruses with antitumor immunity22
Oncolytic Zika virus promotes intratumoral T cell infiltration and improves immunotherapy efficacy in glioblastoma22
A novel PD-L1-targeted shark VNAR single-domain-based CAR-T cell strategy for treating breast cancer and liver cancer21
Breast cancer tumor microenvironment affects Treg/IL-17-producing Treg/Th17 cell axis: Molecular and therapeutic perspectives21
Fluorescent imaging for cancer therapy and cancer gene therapy21
AXL receptor is required for Zika virus strain MR-766 infection in human glioblastoma cell lines21
LRPPRC regulates metastasis and glycolysis by modulating autophagy and the ROS/HIF1-α pathway in retinoblastoma21
lncRNA SNHG26 promoted the growth, metastasis, and cisplatin resistance of tongue squamous cell carcinoma through PGK1/Akt/mTOR signal pathway20
Metformin inhibits gastric cancer cell proliferation by regulation of a novel Loc100506691-CHAC1 axis20
Oncolytic reovirus-mediated recruitment of early innate immune responses reverses immunotherapy resistance in prostate tumors20
Progress and application of circulating tumor cells in non-small cell lung cancer20
CXCR5 guides migration and tumor eradication of anti-EGFR chimeric antigen receptor T cells20
A brief review of reporter gene imaging in oncolytic virotherapy and gene therapy20
Efficacy and safety of a third-generation oncolytic herpes virus G47Δ in models of human esophageal carcinoma20
Intraperitoneal oncolytic virotherapy for patients with malignant ascites: Characterization of clinical efficacy and antitumor immune response20
Tumor-derived exosomal microRNA-7-5p enhanced by verbascoside inhibits biological behaviors of glioblastoma in vitro and in vivo20
A PD1 targeted nano-delivery system based on epigenetic alterations of T cell responses in the treatment of gastric cancer20
USMB-shMincle: a virus-free gene therapy for blocking M1/M2 polarization of tumor-associated macrophages19
Circular RNAs act as regulators of autophagy in cancer19
IFN-I-tolerant oncolytic Semliki Forest virus in combination with anti-PD1 enhances T cell response against mouse glioma19
Extending traditional antibody therapies: Novel discoveries in immunotherapy and clinical applications19
CRISPR-Cas knockout of miR21 reduces glioma growth19
Transcriptional landscape associated with TNBC resistance to neoadjuvant chemotherapy revealed by single-cell RNA-seq19
METTL3 increases cisplatin chemosensitivity of cervical cancer cells via downregulation of the activity of RAGE19
The role of long non-coding RNAs in the pathogenesis of head and neck squamous cell carcinoma19
miR-19a/b promote EMT and proliferation in glioma cells via SEPT7-AKT-NF-κB pathway19
Preclinical Evaluation of the Oncolytic Vaccinia Virus TG6002 by Translational Research on Canine Breast Cancer18
Circular RNA circRAB31 acts as a miR-885-5p sponge to suppress gastric cancer progression via the PTEN/PI3K/AKT pathway18
Efficient antitumor effects of a novel oncolytic adenovirus fully composed of species B adenovirus serotype 3518
Anti-CAIX BBζ CAR4/8 T cells exhibit superior efficacy in a ccRCC mouse model18
Development of non-viral, ligand-dependent, EPHB4-specific chimeric antigen receptor T cells for treatment of rhabdomyosarcoma18
Integrated analysis reveals the molecular features of fibrosis in triple-negative breast cancer18
lncRNA MIR503HG inhibits cell proliferation and promotes apoptosis in TNBC cells via the miR-224-5p/HOXA9 axis18
Therapeutic potential of IBP as an autophagy inducer for treating lung cancer via blocking PAK1/Akt/mTOR signaling17
CCL18 promotes breast cancer progression by exosomal miR-760 activation of ARF6/Src/PI3K/Akt pathway17
Quantitative proteomics characterization of cancer biomarkers and treatment17
Superior infectivity of the fiber chimeric oncolytic adenoviruses Ad5/35 and Ad5/3 over Ad5-delta-24-RGD in primary glioma cultures17
miR-15a and miR-15b modulate natural killer and CD8+T-cell activation and anti-tumor immune response by targeting PD-L1 in neuroblastoma17
Combining vanadyl sulfate with Newcastle disease virus potentiates rapid innate immune-mediated regression with curative potential in murine cancer models17
Noncoding RNA-mediated macrophage and cancer cell crosstalk in hepatocellular carcinoma17
Improving the Efficacy of EGFR Inhibitors by Topical Treatment of Cutaneous Squamous Cell Carcinoma with miR-634 Ointment17
Intracranial delivery of synthetic mRNA to suppress glioblastoma16
Upregulated CBX8 Promotes Cancer Metastasis via the WNK2/MMP2 Pathway16
Recombinant SLAMblind Measles Virus Is a Promising Candidate for Nectin-4-Positive Triple Negative Breast Cancer Therapy16
CD47-targeted cancer immunogene therapy: Secreted SIRPα-Fc fusion protein eradicates tumors by macrophage and NK cell activation16
Applications of nuclear-based imaging in gene and cell therapy: Probe considerations16
Poly(beta-amino ester) nanoparticles enable tumor-specific TRAIL secretion and a bystander effect to treat liver cancer16
Circular RNA SERPINE2 promotes development of glioblastoma by regulating the miR-361-3p/miR-324-5p/BCL2 signaling pathway16
MicroRNA-sensitive oncolytic measles virus for chemovirotherapy of pancreatic cancer16
Combination microRNA-based cellular reprogramming with paclitaxel enhances therapeutic efficacy in a relapsed and multidrug-resistant model of epithelial ovarian cancer16
SNX5 suppresses clear cell renal cell carcinoma progression by inducing CD44 internalization and epithelial-to-mesenchymal transition15
Dual targeting of EZH1 and EZH2 for the treatment of malignant rhabdoid tumors15
A one-step construction of adenovirus (OSCA) system using the Gibson DNA Assembly technology15
In vivo CART cell imaging: Paving the way for success in CART cell therapy15
Nucleic acids and proteins carried by exosomes of different origins as potential biomarkers for gynecologic cancers15
Oncolytic herpes virus G47Δ injected into tongue cancer swiftly traffics in lymphatics and suppresses metastasis15
The IAP antagonist birinapant enhances chimeric antigen receptor T cell therapy for glioblastoma by overcoming antigen heterogeneity15
Comprehensive landscape of tRNA-derived fragments in lung cancer15
Gene knock-out chain reaction enables high disruption efficiency of HPV18 E6/E7 genes in cervical cancer cells15
Vorolanib, a novel tyrosine receptor kinase receptor inhibitor with potent preclinical anti-angiogenic and anti-tumor activity15
Silencing ZIC2 abrogates tumorigenesis and anoikis resistance of non-small cell lung cancer cells by inhibiting Src/FAK signaling15
Hyaluronidase expression within tumors increases virotherapy efficacy and T cell accumulation15
An effective therapeutic regime for treatment of glioma using oncolytic vaccinia virus expressing IL-21 in combination with immune checkpoint inhibition15
Narciclasine targets STAT3 via distinct mechanisms in tamoxifen-resistant breast cancer cells15
Fidarestat induces glycolysis of NK cells through decreasing AKR1B10 expression to inhibit hepatocellular carcinoma14
Oncolytic adenovirus-mediated expression of decorin facilitates CAIX-targeting CAR-T therapy against renal cell carcinoma14
R-2HG downregulates ERα to inhibit cholangiocarcinoma via the FTO/m6A-methylated ERα/miR16-5p/YAP1 signal pathway14
Combination of a STAT3 inhibitor with anti-PD-1 immunotherapy is an effective treatment regimen for a vemurafenib-resistant melanoma14
Immunotherapy by mesenchymal stromal cell delivery of oncolytic viruses for treating metastatic tumors14
Development and comparison of 68Ga/18F/64Cu-labeled nanobody tracers probing Claudin18.214
UXT, a novel DNMT3b-binding protein, promotes breast cancer progression via negatively modulating lncRNA MEG3/p53 axis14
Lazertinib improves the efficacy of chemotherapeutic drugs in ABCB1 or ABCG2 overexpression cancer cells in vitro, in vivo, and ex vivo14
Long non-coding RNAs and circular RNAs in tumor angiogenesis: From mechanisms to clinical significance14
Current advances of liquid biopsies in prostate cancer: Molecular biomarkers14
Eliminating mesothelioma by AAV-vectored, PD1-based vaccination in the tumor microenvironment14
DNA-methylation-induced silencing of DIO3OS drives non-small cell lung cancer progression via activating hnRNPK-MYC-CDC25A axis14
Novel two-chain structure utilizing KIRS2/DAP12 domain improves the safety and efficacy of CAR-T cells in adults with r/r B-ALL13
Intravesical immunotherapy with a GM-CSF armed oncolytic vesicular stomatitis virus improves outcome in bladder cancer13
Disruption of CISH promotes the antitumor activity of human T cells and decreases PD-1 expression levels13
RUNX1/EGFR pathway contributes to STAT3 activation and tumor growth caused by hyperactivated mTORC113
Oncogenic lncRNA BBOX1-AS1 promotes PHF8-mediated autophagy and elicits sorafenib resistance in hepatocellular carcinoma13
Repurposing Pimavanserin, an Anti-Parkinson Drug for Pancreatic Cancer Therapy13
Feasibility study of a novel preparation strategy for anti-CD7 CAR-T cells with a recombinant anti-CD7 blocking antibody13
Arming HSV-Based Oncolytic Viruses with the Ability to Redirect the Host’s Innate Antiviral Immunity to Attack Tumor Cells13
circBANP promotes colorectal cancer growth and metastasis via sponging let-7d-5p to modulate HMGA1/Wnt/β-catenin signaling13
Structure-based virtual screening identifies an 8-hydroxyquinoline as a small molecule GLI1 inhibitor13
Cardamonin suppresses pro-tumor function of macrophages by decreasing M2 polarization on ovarian cancer cells via mTOR inhibition13
S119N Mutation of the E3 Ubiquitin Ligase SPOP Suppresses SLC7A1 Degradation to Regulate Hepatoblastoma Progression12
Purple sweet potato delphinidin-3-rutin represses glioma proliferation by inducing miR-20b-5p/Atg7-dependent cytostatic autophagy12
A library of cancer testis specific T cell receptors for T cell receptor gene therapy12
Multiple targeted self-emulsifying compound RGO reveals obvious anti-tumor potential in hepatocellular carcinoma12
miR-301 regulates the SIRT1/SOX2 pathway via CPEB1 in the breast cancer progression12
Non-coding RNAs in melanoma: Biological functions and potential clinical applications12
TBC1D3 family is a prognostic biomarker and correlates with immune infiltration in kidney renal clear cell carcinoma12
IL-13Rα2 humanized scFv-based CAR-T cells exhibit therapeutic activity against glioblastoma12
Introducing a new reporter gene, membrane-anchored Cypridina luciferase, for multiplex bioluminescence imaging12
Intratumoral delivery of a novel oncolytic adenovirus encoding human antibody against PD-1 elicits enhanced antitumor efficacy12
Development of STEAP1 targeting chimeric antigen receptor for adoptive cell therapy against cancer12
Dual-targeting vaccine of FGL1/CAIX exhibits potent anti-tumor activity by activating DC-mediated multi-functional CD8 T cell immunity12
Emerging function and clinical significance of extracellular vesicle noncoding RNAs in lung cancer12
E26 transformation-specific variant 4 as a tumor promotor in human cancers through specific molecular mechanisms12
Non-coding RNAs and glioma: Focus on cancer stem cells12
Involvement of actin cytoskeletal modifications in the inhibition of triple-negative breast cancer growth and metastasis by nimbolide12
A novel vaccinia virus enhances anti-tumor efficacy and promotes a long-term anti-tumor response in a murine model of colorectal cancer11
CAFs/tumor cells co-targeting DNA vaccine in combination with low-dose gemcitabine for the treatment of Panc02 murine pancreatic cancer11
An oral cancer vaccine using a Bifidobacterium vector suppresses tumor growth in a syngeneic mouse bladder cancer model11
Upregulation of deubiquitinase USP7 by transcription factor FOXO6 promotes EC progression via targeting the JMJD3/CLU axis11
Upregulation of endogenous TRAIL-elicited apoptosis is essential for metformin-mediated antitumor activity against TNBC and NSCLC11
Hsa_circ_0001666 promotes non-small cell lung cancer migration and invasion through miR-1184/miR-548I/AGO1 axis11
Selective sodium iodide symporter (NIS) gene therapy of glioblastoma mediated by EGFR-targeted lipopolyplexes11
The miR-23a/27a/24-2 cluster promotes postoperative progression of early-stage non-small cell lung cancer11
Nuclear export protein CSE1L interacts with P65 and promotes NSCLC growth via NF-κB/MAPK pathway11
Anti-tumor immunity enhancement by photodynamic therapy with talaporfin sodium and anti-programmed death 1 antibody11
Current development in adenoviral vectors for cancer immunotherapy11
PROTACs in gastrointestinal cancers11
A host non-coding RNA, nc886, plays a pro-viral role by promoting virus trafficking to the nucleus11
Improved lentiviral vector titers from a multi-gene knockout packaging line11
hsa_circ_0085539 Promotes Osteosarcoma Progression by Regulating miR-526b-5p and SERP110
Modulation of p53 expression in cancer-associated fibroblasts prevents peritoneal metastasis of gastric cancer10
Reinvigoration of innate and adaptive immunity via therapeutic cellular vaccine for patients with AML10
Anti-oncogenic activities exhibited by paracrine factors of MSCs can be mediated by modulation of KITLG and DKK1 genes in glioma SCs in vitro10
A survivin-driven, tumor-activatable minicircle system for prostate cancer theranostics10
Oncolytic measles vaccines encoding PD-1 and PD-L1 checkpoint blocking antibodies to increase tumor-specific T cell memory10
Expanding the role of interventional oncology for advancing precision immunotherapy of solid tumors10
A novel CD34-derived hinge for rapid and efficient detection and enrichment of CAR T cells10
Concurrent expression of HP-NAP enhances antitumor efficacy of oncolytic vaccinia virus but not for Semliki Forest virus10
Inhibition of MEK-ERK pathway enhances oncolytic vaccinia virus replication in doxorubicin-resistant ovarian cancer10
ScRNA-seq and bulk RNA-seq reveal the characteristics of ferroptosis and establish a risk signature in cholangiocarcinoma10
A novel anti-B7-H3 chimeric antigen receptor from a single-chain antibody library for immunotherapy of solid cancers10
Targeting primary and metastatic tumor growth in an aggressive breast cancer by engineered tryptophan auxotrophic Salmonella Typhimurium10
Immune priming using DC- and T cell-targeting gene therapy sensitizes both treated and distant B16 tumors to checkpoint inhibition10
Berberine inhibits carcinogenesis through antagonizing the ATX-LPA-LPAR2-p38-leptin axis in a mouse hepatoma model9
Anti-CD117 CAR T cells incorporating a safety switch eradicate human acute myeloid leukemia and hematopoietic stem cells9
Local adenoviral delivery of soluble CD200R-Ig enhances antitumor immunity by inhibiting CD200-β-catenin-driven M2 macrophage9
Targeting SOS1 overcomes imatinib resistance with BCR-ABL independence through uptake transporter SLC22A4 in CML9
Induction of cell death in ovarian cancer cells by doxorubicin and oncolytic vaccinia virus is associated with CREB3L1 activation9
Modulation of mTOR and epigenetic pathways as therapeutics in gallbladder cancer9
LINC00461 facilitates HNSCC development and reduces chemosensitivity by impairing miR-195-mediated inhibition of HOXA109
Dual EGFR- and TfR-targeted gene transfer for sodium iodide symporter gene therapy of glioblastoma9
Oncolytic vaccinia virus injected intravenously sensitizes pancreatic neuroendocrine tumors and metastases to immune checkpoint blockade9
PI3K-activated MSC proteomes inhibit mammary tumors via Hsp90ab1 and Myh99
CXCL2 combined with HVJ-E suppresses tumor growth and lung metastasis in breast cancer and enhances anti-PD-1 antibody therapy9
Chimeric anti-GPC3 sFv-CD3ε receptor-modified T cells with IL7 co-expression for the treatment of solid tumors9
Efficient delivery of oncolytic enterovirus by carrier cell line NK-929
Expression of Oncolytic Adenovirus-Encoded RNAi Molecules Is Most Effective in a pri-miRNA Precursor Format9
Infection of non-cancer cells: A barrier or support for oncolytic virotherapy?9
Zika virus cleaves GSDMD to disseminate prognosticable and controllable oncolysis in a human glioblastoma cell model9
Deletion of immunomodulatory genes as a novel approach to oncolytic vaccinia virus development9
LINC01296 promotes neuroblastoma tumorigenesis via the NCL-SOX11 regulatory complex9
Cannabinoid receptors promote chronic intermittent hypoxia-induced breast cancer metastasis via IGF-1R/AKT/GSK-3β9
A novel protein-drug conjugate, SSH20, demonstrates significant efficacy in caveolin-1-expressing tumors9
AAMP promotes colorectal cancer metastasis by suppressing SMURF2-mediated ubiquitination and degradation of RhoA9
A synDNA vaccine delivering neoAg collections controls heterogenous, multifocal murine lung and ovarian tumors via robust T cell generation9
Acquired chemoresistance can lead to increased resistance of pancreatic cancer cells to oncolytic vesicular stomatitis virus9
Gene-edited and CAR-NK cells: Opportunities and challenges with engineering of NK cells for immunotherapy9
Knockdown of SENP1 inhibits HIF-1α SUMOylation and suppresses oncogenic CCNE1 in Wilms tumor9
Metformin preferentially enhances the radio-sensitivity of cancer stem-like cells with highly mitochondrial respiration ability in HMPOS9
Association of MicroRNA-21 with p53 at Mutant Sites R175H and R248Q, Clinicopathological Features, and Prognosis of NSCLC9
Therapeutic effects of mesenchymal stem cells loaded with oncolytic adenovirus carrying decorin on a breast cancer lung metastatic mouse model8
miR-1207-5p suppresses laryngeal squamous cell carcinoma progression by downregulating SKA3 and inhibiting epithelial-mesenchymal transition8
Comprehensive analysis of lncRNAs as biomarkers for diagnosis, prognosis, and treatment response in clear cell renal cell carcinoma8
Cholesterol-enriched membrane micro-domain deficiency induces doxorubicin resistance via promoting autophagy in breast cancer8
A systematic analysis on the clinical safety and efficacy of onco-virotherapy8
Metabolic remodeling in tumor-associated macrophages contributing to antitumor activity of cryptotanshinone by regulating TRAF6-ASK1 axis8
Genomic instability in lower-grade glioma: Prediction of prognosis based on lncRNA and immune infiltration8
Preclinical evaluation of a novel antibody-drug conjugate targeting DR5 for lymphoblastic leukemia therapy8
Development of a low-seroprevalence, αvβ6 integrin-selective virotherapy based on human adenovirus type 108
Circular RNA circLAMA3 inhibits the proliferation of bladder cancer by directly binding an mRNA8
A polygenic methylation prediction model associated with response to chemotherapy in epithelial ovarian cancer8
Oncolytic herpes simplex virus infects myeloma cells in vitro and in vivo8
Oleanolic acid blocks the purine salvage pathway for cancer therapy by inactivating SOD1 and stimulating lysosomal proteolysis8
Exploring the Role of TRIP-Brs in Human Breast Cancer: An Investigation of Expression, Clinicopathological Significance, and Prognosis8
Remission of liquid tumors and SARS-CoV-2 infection: A literature review8
The pivotal regulatory factor circBRWD1 inhibits arsenic exposure-induced lung cancer occurrence by binding mRNA and regulating its stability8
Polymer stealthing and mucin-1 retargeting for enhanced pharmacokinetics of an oncolytic vaccinia virus8
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