OOIR: Observatory of International Research

Papers

(The H4-Index of eBioMedicine is 81. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)

Article	Citations
SLE and purine metabolizing ecto-enzymes	470
Mechanotransduction as a therapeutic target for brain tumours	420
Corrigendum to “Single-cell RNA transcriptomics in mice reveals embryonic origin of fibrosis due to maternal obesity” [eBioMedicine 109(2024) 105421]	337
High level of plasma TILRR protein is associated with faster HIV seroconversion	336
Corrigendum to “PTGER3 induces ovary tumorigenesis and confers resistance to cisplatin therapy through up-regulation Ras-MAPK/Erk-ETS1-ELK1/CFTR1 axis” [EBioMedicine 40 (2019) 290-304]	329
Erratum to “Tumor cells hijack enteric glia to activate colon cancer stem cells and stimulate tumorigenesis” [EBioMedicine 49 (2019) 172–188]	320
Corrigendum to “The significance of recurrent de novo amino acid substitutions that emerged during chronic SARS-CoV-2 infection: an observational study” [eBioMedicine, 2024;107:105273]	286
Same-day confirmation of infection and antimicrobial susceptibility profiling using flow cytometry	253
Multifaceted autoimmunity: new challenges and new approaches	241
Association between wearable sensor signals and expected hormonal changes in pregnancy	218
Contributions of inherited mtDNA to longevity: evidence from extended pedigrees with 176 million kinship pairs	211
Somatic hypermutation shapes the viral escape profile of SARS-CoV-2 neutralising antibodies	210
Super-resolution ultrasound imaging reveals temporal cerebrovascular changes with disease progression in female 5×FAD mouse model of Alzheimer's disease: correlation with pathological impairments	208
Adults with Plasmodium falciparum malaria have higher magnitude and quality of circulating T-follicular helper cells compared to children	208
High serum C-X-C motif chemokine ligand 10 (CXCL10) levels may be associated with new onset interstitial lung disease in patients with systemic sclerosis: evidence from observational, clinical, transc	205
Precision diagnostic approach to predict 5-year risk for microvascular complications in type 1 diabetes	203
Modeling of cancer-related body-wide effects identifies LTB4 as a diagnostic biomarker for pancreatic cancer	191
Machine learning detection of heteroresistance in Escherichia coli	188
Genetic landscape of a large cohort of Primary Ovarian Insufficiency: New genes and pathways and implications for personalized medicine	184
Clinical and genetic characteristics of a large international cohort of individuals with rare NR5A1/SF-1 variants of sex development	182
Probiotics counteract hepatic steatosis caused by ketogenic diet and upregulate AMPK signaling in a model of infantile epilepsy	181
Trajectories of olfactory identification preceding incident mild cognitive impairment and dementia: a longitudinal study	171
Desulfovibrio desulfuricans and its derived metabolites confer resistance to FOLFOX through METTL3	164
Local fistula injection of allogeneic human amnion epithelial cells is safe and well tolerated in patients with refractory complex perianal Crohn's disease: a phase I open label study with long-term f	163
NIR-II fluorescence-guided liver cancer surgery by a small molecular HDAC6 targeting probe	162

A custom-made mouthguard reduces head acceleration during soccer heading and prevents acute electrophysiological and cognitive changes in amateur male players	157
Adenoviral vectored vaccination protects against Crimean-Congo Haemorrhagic Fever disease in a lethal challenge model	155
Next-gen spinal cord injury clinical trials: lessons learned and opportunities for future success	147
Spatial and single-cell colocalisation analysis reveals MDK-mediated immunosuppressive environment with regulatory T cells in colorectal carcinogenesis	146
Longitudinal effects of SARS-CoV-2 breakthrough infection on imprinting of neutralizing antibody responses	140
In SARS-CoV-2 delta variants, Spike-P681R and D950N promote membrane fusion, Spike-P681R enhances spike cleavage, but neither substitution affects pathogenicity in hamsters	137
Daily variation in blood glucose levels during continuous enteral nutrition in patients on the intensive care unit: a retrospective observational study	136
The gene environment aetiology of freezing and its relationship with internalizing symptoms during adolescence	133
Resolving immune cells with patrolling behaviour by magnetic resonance time-lapse single cell tracking	131
Neolithic introgression of IL23R-related protection against chronic inflammatory bowel diseases in modern Europeans	129
The anti-leprosy drug clofazimine reduces polyQ toxicity through activation of PPARγ	127
T cell response against SARS-CoV-2 persists after one year in patients surviving severe COVID-19	127
Bi-allelic LAMP3 variants in childhood interstitial lung disease: a surfactant-related disease	122
A computational framework to improve cross-platform implementation of transcriptomics signatures	122
NR4A3 prevents diabetes induced atrial cardiomyopathy by maintaining mitochondrial energy metabolism and reducing oxidative stress	116
Forever chemicals: the persistent effects of perfluoroalkyl and polyfluoroalkyl substances on human health	115
Patient-derived melanoma organoid models facilitate the assessment of immunotherapies	113
Phase 2a/b randomised placebo-controlled dose-escalation trial of triheptanoin for ataxia-telangiectasia: treating mitochondrial dysfunction with anaplerosis	112
Evaluation of pre-diagnostic blood protein measurements for predicting survival after lung cancer diagnosis	108
Ebola-Detect: A differential serodiagnostic assay for Ebola virus infections and surveillance in the presence of vaccine-induced antibodies	108
Grandmaternal microchimerism: interesting curiosity or clinically relevant phenomenon?	108
Affordable blood culture systems from China: in vitro evaluation for use in resource-limited settings	105
A multiple sclerosis patient-oriented multiomics analysis tells us where to go next: Commentary for: “Alterations of host-gut microbiome interactions in multiple sclerosis”	105
Circular-SWAT for deep learning based diagnostic classification of Alzheimer's disease: application to metabolome data	104
Dilated Virchow Robin spaces in multiple sclerosis – a generalised marker of disease?	104
Diphtheria's resurgence and the high cost of misinformation	104
Association of body composition with neuroimaging biomarkers and cognitive function; a population-based study of 70-year-olds	103
Physical inactivity exacerbates pathologic inflammatory signalling at the single cell level in patients with systemic lupus	103
Quantitative stiffness assessment of cardiac grafts using ultrasound in a porcine model: A tissue biomarker for heart transplantation	102
Authors' reply to letter regarding “Inflammaging links life's essential 8 to white matter brain aging”	100
Molecular modelling of the FOXO4-TP53 interaction to design senolytic peptides for the elimination of senescent cancer cells	100
Do interventions for mood improve inflammatory biomarkers in inflammatory bowel disease?: a systematic review and meta-analysis	100
Exploring electroencephalographic chronic pain biomarkers: a mega-analysis	99
α-Synuclein seed amplification assay positivity beyond synucleinopathies	98
Different oxytocin and corticotropin-releasing hormone system changes in bipolar disorder and major depressive disorder patients	98
Selective emergence of antibody-secreting cells in the multiple sclerosis brain	96
Effect of intra-partum azithromycin on the development of the infant nasopharyngeal microbiota: A post hoc analysis of a double-blind randomized trial	96
A pancreatic cancer risk prediction model (Prism) developed and validated on large-scale US clinical data	94
Long-term safety and immunogenicity of an MF59-adjuvanted spike glycoprotein-clamp vaccine for SARS-CoV-2 in adults aged 18–55 years or ≥56 years: 12-month results from a randomised, double-blind, pla	92
Development of a translational inflammation panel for the quantification of cerebrospinal fluid Pterin, Tryptophan-Kynurenine and Nitric oxide pathway metabolites	91
Elevated hippocampal copper in cases of type 2 diabetes	89
Interim results from a phase I randomized, placebo-controlled trial of novel SARS-CoV-2 beta variant receptor-binding domain recombinant protein and mRNA vaccines as a 4th dose booster	89
Phase 2, randomized, double-blind, placebo-controlled multi-center trial of the clinical and biological effects of anti-CD14 treatment in hospitalized patients with COVID-19 pneumonia	88
Imaging brain development in a KCNQ2-developmental and epileptic encephalopathy mouse model: identifying early biomarkers for functional and structural brain changes	87
Using gene-environment interactions to explore pathways for colorectal cancer risk	87
Genome-wide interaction study of dietary intake of fibre, fruits, and vegetables with risk of colorectal cancer	87
A comprehensive assessment of the association between common drugs and psychiatric disorders using Mendelian randomization and real-world pharmacovigilance database	86
Hypoxia activated HGF expression in pancreatic stellate cells confers resistance of pancreatic cancer cells to EGFR inhibition	85
Gut microbiome and atrial fibrillation—results from a large population-based study	85
Alzheimer's disease protease-containing plasma extracellular vesicles transfer to the hippocampus via the choroid plexus	84

The distinct genetic features of pancreatic cancer in Chinese population	83
Mst1-mediated phosphorylation of Nur77 improves the endometrial receptivity in human and mice	83
Circadian rhythms in haematological malignancies: therapeutic potential and personalised interventions	83
Newborn glomerular function and gestational particulate air pollution	82
Associations of family affluence with cortisol production and telomere length in European children	82
Pathological diagnosis and prognosis of Gastric cancer through a multi-instance learning method	82
Molecular imaging in experimental pulmonary fibrosis reveals that nintedanib unexpectedly modulates CCR2 immune cell infiltration	81
Association between hearing ability and cortical morphology in the elderly: multiparametric mapping, cognitive relevance, and neurobiological underpinnings	81