OOIR: Observatory of International Research

Papers

(The H4-Index of eBioMedicine is 72. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Short chain fatty acids and its producing organisms: An overlooked therapy for IBD?	366
Persistence of viral RNA, pneumocyte syncytia and thrombosis are hallmarks of advanced COVID-19 pathology	297
Camostat mesylate inhibits SARS-CoV-2 activation by TMPRSS2-related proteases and its metabolite GBPA exerts antiviral activity	240
Contribution of ferroptosis and GPX4’s dual functions to osteoarthritis progression	214
Microplastics detected in cirrhotic liver tissue	212
Therapeutic targeting of “undruggable” MYC	188
Effect of SARS-CoV-2 mRNA vaccination in MS patients treated with disease modifying therapies	183
Evolution of antibody responses up to 13 months after SARS-CoV-2 infection and risk of reinfection	180
Lactate in the tumour microenvironment: From immune modulation to therapy	174
Safety and efficacy of the mRNA BNT162b2 vaccine against SARS-CoV-2 in five groups of immunocompromised patients and healthy controls in a prospective open-label clinical trial	169
Intranasal COVID-19 vaccines: From bench to bed	161
Mucosal immune response in BNT162b2 COVID-19 vaccine recipients	157
Metabolomics of exhaled breath in critically ill COVID-19 patients: A pilot study	156
Attention is not all you need: the complicated case of ethically using large language models in healthcare and medicine	156
Improving CAR-T immunotherapy: Overcoming the challenges of T cell exhaustion	155
Host genetic factors determining COVID-19 susceptibility and severity	151
Kidney damage causally affects the brain cortical structure: A Mendelian randomization study	142
Characterizing Long COVID: Deep Phenotype of a Complex Condition	139
Magnetic resonance imaging radiomics predicts preoperative axillary lymph node metastasis to support surgical decisions and is associated with tumor microenvironment in invasive breast cancer: A machi	139
Emerging SARS-CoV-2 variants expand species tropism to murines	133
Analytical and clinical performances of five immunoassays for the detection of SARS-CoV-2 antibodies in comparison with neutralization activity	131
Single-cell RNA-seq reveals dynamic change in tumor microenvironment during pancreatic ductal adenocarcinoma malignant progression	128
The gut virome: A new microbiome component in health and disease	126
Gut microbiota and its metabolites in depression: from pathogenesis to treatment	124
Circulating tumor cell isolation for cancer diagnosis and prognosis	123

Increased viral variants in children and young adults with impaired humoral immunity and persistent SARS-CoV-2 infection: A consecutive case series	121
SARS-CoV-2 persistence is associated with antigen-specific CD8 T-cell responses	119
Machine learning for brain age prediction: Introduction to methods and clinical applications	114
Limited neutralisation of the SARS-CoV-2 Omicron subvariants BA.1 and BA.2 by convalescent and vaccine serum and monoclonal antibodies	112
Neurochemical signs of astrocytic and neuronal injury in acute COVID-19 normalizes during long-term follow-up	112
Increased resistance of SARS-CoV-2 Omicron variant to neutralization by vaccine-elicited and therapeutic antibodies	112
Microbiota and the gut-brain-axis: Implications for new therapeutic design in the CNS	112
Q493K and Q498H substitutions in Spike promote adaptation of SARS-CoV-2 in mice	111
Appraising the causal role of smoking in multiple diseases: A systematic review and meta-analysis of Mendelian randomization studies	108
Benchmarking large language models’ performances for myopia care: a comparative analysis of ChatGPT-3.5, ChatGPT-4.0, and Google Bard	104
Clinical tools and biomarkers to predict preeclampsia	104
The complex genetic architecture of Alzheimer's disease: novel insights and future directions	102
Epigenome-wide association study of COVID-19 severity with respiratory failure	99
Comparing infectivity and virulence of emerging SARS-CoV-2 variants in Syrian hamsters	99
Klebsiella species: Taxonomy, hypervirulence and multidrug resistance	98
Deep-learning-assisted detection and segmentation of rib fractures from CT scans: Development and validation of FracNet	98
The combined treatment of Molnupiravir and Favipiravir results in a potentiation of antiviral efficacy in a SARS-CoV-2 hamster infection model	98
Inflammation and resolution signaling in cardiac repair and heart failure	98
Waning immune responses against SARS-CoV-2 variants of concern among vaccinees in Hong Kong	97
Cerebrospinal fluid p-tau231 as an early indicator of emerging pathology in Alzheimer's disease	91
SARS-CoV-2 leads to a small vessel endotheliitis in the heart	90
MRI-based machine learning radiomics can predict HER2 expression level and pathologic response after neoadjuvant therapy in HER2 overexpressing breast cancer	90
Predicting sepsis severity at first clinical presentation: The role of endotypes and mechanistic signatures	89
MUC2 and related bacterial factors: Therapeutic targets for ulcerative colitis	89
Integrative analysis from multi-center studies identities a consensus machine learning-derived lncRNA signature for stage II/III colorectal cancer	87
Loss of TRIM21 alleviates cardiotoxicity by suppressing ferroptosis induced by the chemotherapeutic agent doxorubicin	86
Discordant humoral and T cell immune responses to SARS-CoV-2 vaccination in people with multiple sclerosis on anti-CD20 therapy	85
Artificial intelligence quantified tumour-stroma ratio is an independent predictor for overall survival in resectable colorectal cancer	85
Tolerability and immunogenicity of an intranasally-administered adenovirus-vectored COVID-19 vaccine: An open-label partially-randomised ascending dose phase I trial	84
Clinical features and prognostic factors in Covid-19: A prospective cohort study	84
Decreased miR-214–3p activates NF-κB pathway and aggravates osteoarthritis progression	83
Generalisable long COVID subtypes: findings from the NIH N3C and RECOVER programmes	81
SARS-CoV-2 Omicron BA.5: Evolving tropism and evasion of potent humoral responses and resistance to clinical immunotherapeutics relative to viral variants of concern	81
Specific inhibition of the NLRP3 inflammasome suppresses immune overactivation and alleviates COVID-19 like pathology in mice	81
The displacement of the SARS-CoV-2 variant Delta with Omicron: An investigation of hospital admissions and upper respiratory viral loads	80
Physical exercise is a risk factor for amyotrophic lateral sclerosis: Convergent evidence from Mendelian randomisation, transcriptomics and risk genotypes	79
Newcastle disease virus (NDV) expressing the spike protein of SARS-CoV-2 as a live virus vaccine candidate	79
Heterologous ChAdOx1 nCoV-19 and BNT162b2 prime-boost vaccination elicits potent neutralizing antibody responses and T cell reactivity against prevalent SARS-CoV-2 variants	78
CUP-AI-Dx: A tool for inferring cancer tissue of origin and molecular subtype using RNA gene-expression data and artificial intelligence	77
Multi-omics approaches for biomarker discovery in early ovarian cancer diagnosis	76
Prophylactic intranasal administration of a TLR2/6 agonist reduces upper respiratory tract viral shedding in a SARS-CoV-2 challenge ferret model	76
Predictive and prognostic impact of ferroptosis-related genes ACSL4 and GPX4 on breast cancer treated with neoadjuvant chemotherapy	74
Recent advances in the mechanisms and treatment of immune thrombocytopenia	74
Circulating extracellular vesicles are endowed with enhanced procoagulant activity in SARS-CoV-2 infection	74
Alterations of host-gut microbiome interactions in multiple sclerosis	74
Shared genetic etiology between idiopathic pulmonary fibrosis and COVID-19 severity	74
Bifidobacterium longum counters the effects of obesity: Partial successful translation from rodent to human	73
Immunopathophysiology of human sepsis	72
Pharmacological advances in mitochondrial therapy	72
A linear prognostic score based on the ratio of interleukin-6 to interleukin-10 predicts outcomes in COVID-19	72

Oral administration of maternal vaginal microbes at birth to restore gut microbiome development in infants born by caesarean section: A pilot randomised placebo-controlled trial