OOIR: Observatory of International Research

Papers

(The H4-Index of eBioMedicine is 79. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
Authors' reply to letter regarding “Inflammaging links life's essential 8 to white matter brain aging”	614
Clinical and genetic characteristics of a large international cohort of individuals with rare NR5A1/SF-1 variants of sex development	552
Quantifying rate-limiting genetic variation in breast and ovarian tumourigenesis	373
High-dimensional single-cell analyses reveal neutrophil heterogeneity in guttate psoriasis	327
Somatic structural variants drive upper tract urothelial carcinoma muscle invasiveness via activation of TPX2 transcription	288
α-Synuclein seed amplification assay positivity beyond synucleinopathies	287
Precision diagnostic approach to predict 5-year risk for microvascular complications in type 1 diabetes	266
NIR-II fluorescence-guided liver cancer surgery by a small molecular HDAC6 targeting probe	254
Corrigendum to “PTGER3 induces ovary tumorigenesis and confers resistance to cisplatin therapy through up-regulation Ras-MAPK/Erk-ETS1-ELK1/CFTR1 axis” [EBioMedicine 40 (2019) 290-304]	250
Phase 2a/b randomised placebo-controlled dose-escalation trial of triheptanoin for ataxia-telangiectasia: treating mitochondrial dysfunction with anaplerosis	245
Daily variation in blood glucose levels during continuous enteral nutrition in patients on the intensive care unit: a retrospective observational study	240
Trajectories of olfactory identification preceding incident mild cognitive impairment and dementia: a longitudinal study	221
Ebola-Detect: A differential serodiagnostic assay for Ebola virus infections and surveillance in the presence of vaccine-induced antibodies	214
Quantitative stiffness assessment of cardiac grafts using ultrasound in a porcine model: A tissue biomarker for heart transplantation	213
Long-term safety and immunogenicity of an MF59-adjuvanted spike glycoprotein-clamp vaccine for SARS-CoV-2 in adults aged 18–55 years or ≥56 years: 12-month results from a randomised, double-blind, pla	199
Neurodevelopmental origins of age-related neurodegenerative diseases	178
Letter in response to “Kappa free light chain index as a substitute to oligoclonal bands in diagnosing multiple sclerosis”	174
Glucose levels are associated with mood, but the association is mediated by ratings of metabolic state	174
Gut microbiome and atrial fibrillation—results from a large population-based study	160
Diphtheria's resurgence and the high cost of misinformation	150
Erratum to “Tumor cells hijack enteric glia to activate colon cancer stem cells and stimulate tumorigenesis” [EBioMedicine 49 (2019) 172–188]	147
Corrigendum to “The significance of recurrent de novo amino acid substitutions that emerged during chronic SARS-CoV-2 infection: an observational study” [eBioMedicine, 2024;107:105273]	142
Corrigendum to “Single-cell RNA transcriptomics in mice reveals embryonic origin of fibrosis due to maternal obesity” [eBioMedicine 109(2024) 105421]	138
Corrigendum to “Pro-dopaminergic pharmacological interventions for anhedonia in depression: a living systematic review and network meta-analysis of human and animal studies”, EBioMedicine. 2025 Nov;12	138
Genome-wide interaction study of dietary intake of fibre, fruits, and vegetables with risk of colorectal cancer	135

Hypoxia activated HGF expression in pancreatic stellate cells confers resistance of pancreatic cancer cells to EGFR inhibition	134
Exploring electroencephalographic chronic pain biomarkers: a mega-analysis	132
Selective emergence of antibody-secreting cells in the multiple sclerosis brain	131
Mechanotransduction as a therapeutic target for brain tumours	129
Adenoviral vectored vaccination protects against Crimean-Congo Haemorrhagic Fever disease in a lethal challenge model	124
Spatial and single-cell colocalisation analysis reveals MDK-mediated immunosuppressive environment with regulatory T cells in colorectal carcinogenesis	123
Genetic landscape of a large cohort of Primary Ovarian Insufficiency: New genes and pathways and implications for personalized medicine	123
Next-gen spinal cord injury clinical trials: lessons learned and opportunities for future success	121
Patient-derived melanoma organoid models facilitate the assessment of immunotherapies	121
A custom-made mouthguard reduces head acceleration during soccer heading and prevents acute electrophysiological and cognitive changes in amateur male players	121
Do interventions for mood improve inflammatory biomarkers in inflammatory bowel disease?: a systematic review and meta-analysis	120
A pancreatic cancer risk prediction model (Prism) developed and validated on large-scale US clinical data	118
Different oxytocin and corticotropin-releasing hormone system changes in bipolar disorder and major depressive disorder patients	117
NR4A3 prevents diabetes induced atrial cardiomyopathy by maintaining mitochondrial energy metabolism and reducing oxidative stress	111
Bi-allelic LAMP3 variants in childhood interstitial lung disease: a surfactant-related disease	108
Forever chemicals: the persistent effects of perfluoroalkyl and polyfluoroalkyl substances on human health	107
In SARS-CoV-2 delta variants, Spike-P681R and D950N promote membrane fusion, Spike-P681R enhances spike cleavage, but neither substitution affects pathogenicity in hamsters	106
Super-resolution ultrasound imaging reveals temporal cerebrovascular changes with disease progression in female 5×FAD mouse model of Alzheimer's disease: correlation with pathological impairments	105
Elevated hippocampal copper in cases of type 2 diabetes	103
A comprehensive assessment of the association between common drugs and psychiatric disorders using Mendelian randomization and real-world pharmacovigilance database	101
Neolithic introgression of IL23R-related protection against chronic inflammatory bowel diseases in modern Europeans	100
Mid- and late-life cardiovascular health indicators and changes in biological ageing Markers; a multi-cohort study	100
Multifaceted autoimmunity: new challenges and new approaches	99
Somatic hypermutation shapes the viral escape profile of SARS-CoV-2 neutralising antibodies	99
Dilated Virchow Robin spaces in multiple sclerosis – a generalised marker of disease?	99
Contributions of inherited mtDNA to longevity: evidence from extended pedigrees with 176 million kinship pairs	98
Sex-specific interaction effects of Syntaxin 1A coexpression network and childhood trauma on adult depressive symptoms	98
Using gene-environment interactions to explore pathways for colorectal cancer risk	98
Phase 2, randomized, double-blind, placebo-controlled multi-center trial of the clinical and biological effects of anti-CD14 treatment in hospitalized patients with COVID-19 pneumonia	96
High serum C-X-C motif chemokine ligand 10 (CXCL10) levels may be associated with new onset interstitial lung disease in patients with systemic sclerosis: evidence from observational, clinical, transc	96
Physical inactivity exacerbates pathologic inflammatory signalling at the single cell level in patients with systemic lupus	94
A computational framework to improve cross-platform implementation of transcriptomics signatures	93
Longitudinal effects of SARS-CoV-2 breakthrough infection on imprinting of neutralizing antibody responses	93
Same-day confirmation of infection and antimicrobial susceptibility profiling using flow cytometry	93
The gene environment aetiology of freezing and its relationship with internalizing symptoms during adolescence	92
Circular-SWAT for deep learning based diagnostic classification of Alzheimer's disease: application to metabolome data	92
Interim results from a phase I randomized, placebo-controlled trial of novel SARS-CoV-2 beta variant receptor-binding domain recombinant protein and mRNA vaccines as a 4th dose booster	90
Machine learning detection of heteroresistance in Escherichia coli	90
Desulfovibrio desulfuricans and its derived metabolites confer resistance to FOLFOX through METTL3	90
Evaluation of pre-diagnostic blood protein measurements for predicting survival after lung cancer diagnosis	89
Effect of intra-partum azithromycin on the development of the infant nasopharyngeal microbiota: A post hoc analysis of a double-blind randomized trial	89
Local fistula injection of allogeneic human amnion epithelial cells is safe and well tolerated in patients with refractory complex perianal Crohn's disease: a phase I open label study with long-term f	89
Affordable blood culture systems from China: in vitro evaluation for use in resource-limited settings	88
Modeling of cancer-related body-wide effects identifies LTB4 as a diagnostic biomarker for pancreatic cancer	88
The anti-leprosy drug clofazimine reduces polyQ toxicity through activation of PPARγ	88
Imaging brain development in a KCNQ2-developmental and epileptic encephalopathy mouse model: identifying early biomarkers for functional and structural brain changes	88
Association of body composition with neuroimaging biomarkers and cognitive function; a population-based study of 70-year-olds	88
Association between wearable sensor signals and expected hormonal changes in pregnancy	87
Metabolomic profiles of infants classified as sudden infant death syndrome: a case-control analysis	84
Association between hearing ability and cortical morphology in the elderly: multiparametric mapping, cognitive relevance, and neurobiological underpinnings	83

Corrigendum to Spread of MCR-3 colistin resistance in China: an epidemiological, genomic and mechanistic study 2018 Aug; 34: 139–157	81
Once-daily dolutegravir/lamivudine fixed-dose formulations in children living with HIV: a pharmacokinetic and safety sub-study nested in the open-label, multicentre, randomised, non-inferiority D3/PEN	81
Aerobic glycolysis imaging of epileptic foci during the inter-ictal period	80
Machine learning-driven identification of the gene-expression signature associated with a persistent multiple organ dysfunction trajectory in critical illness	79
Improving overall child survival in conflict and fragile settings via integration of medical innovations into broader health system strengthening efforts: lessons from six rural hospitals in Somalia	79