OOIR: Observatory of International Research

Papers

(The H4-Index of eBioMedicine is 79. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
A multiple sclerosis patient-oriented multiomics analysis tells us where to go next: Commentary for: “Alterations of host-gut microbiome interactions in multiple sclerosis”	340
Probiotics counteract hepatic steatosis caused by ketogenic diet and upregulate AMPK signaling in a model of infantile epilepsy	286
Quantitative stiffness assessment of cardiac grafts using ultrasound in a porcine model: A tissue biomarker for heart transplantation	265
Predictive nomogram for leprosy using genetic and epidemiological risk factors in Southwestern China: Case–control and prospective analyses	263
A closer look at esophageal cancer through different lenses	262
Multifaceted autoimmunity: new challenges and new approaches	249
Grandmaternal microchimerism: interesting curiosity or clinically relevant phenomenon?	234
Ebola-Detect: A differential serodiagnostic assay for Ebola virus infections and surveillance in the presence of vaccine-induced antibodies	195
Evaluation of pre-diagnostic blood protein measurements for predicting survival after lung cancer diagnosis	189
Modeling of cancer-related body-wide effects identifies LTB4 as a diagnostic biomarker for pancreatic cancer	186
Next-gen spinal cord injury clinical trials: lessons learned and opportunities for future success	185
SLE and purine metabolizing ecto-enzymes	181
Deep learning predicts gene expression as an intermediate data modality to identify susceptibility patterns in Mycobacterium tuberculosis infected Diversity Outbred mice	181
High level of plasma TILRR protein is associated with faster HIV seroconversion	180
Longitudinal effects of SARS-CoV-2 breakthrough infection on imprinting of neutralizing antibody responses	174
Physical inactivity exacerbates pathologic inflammatory signalling at the single cell level in patients with systemic lupus	172
Corrigendum to “The significance of recurrent de novo amino acid substitutions that emerged during chronic SARS-CoV-2 infection: an observational study” [eBioMedicine, 2024;107:105273]	169
The anti-leprosy drug clofazimine reduces polyQ toxicity through activation of PPARγ	168
Erratum to “Tumor cells hijack enteric glia to activate colon cancer stem cells and stimulate tumorigenesis” [EBioMedicine 49 (2019) 172–188]	168
Gut microbiome and atrial fibrillation—results from a large population-based study	166
A comprehensive assessment of the association between common drugs and psychiatric disorders using Mendelian randomization and real-world pharmacovigilance database	164
Corrigendum to “PTGER3 induces ovary tumorigenesis and confers resistance to cisplatin therapy through up-regulation Ras-MAPK/Erk-ETS1-ELK1/CFTR1 axis” [EBioMedicine 40 (2019) 290-304]	163
IBD metabonomics predicts phenotype, disease course, and treatment response	156
A computational framework to improve cross-platform implementation of transcriptomics signatures	155
Resolving immune cells with patrolling behaviour by magnetic resonance time-lapse single cell tracking	152

Forever chemicals: the persistent effects of perfluoroalkyl and polyfluoroalkyl substances on human health	146
Dilated Virchow Robin spaces in multiple sclerosis – a generalised marker of disease?	145
Elevated hippocampal copper in cases of type 2 diabetes	140
Corrigendum to “Single-cell RNA transcriptomics in mice reveals embryonic origin of fibrosis due to maternal obesity” [eBioMedicine 109(2024) 105421]	136
Precision diagnostic approach to predict 5-year risk for microvascular complications in type 1 diabetes	126
Long-term safety and immunogenicity of an MF59-adjuvanted spike glycoprotein-clamp vaccine for SARS-CoV-2 in adults aged 18–55 years or ≥56 years: 12-month results from a randomised, double-blind, pla	126
In SARS-CoV-2 delta variants, Spike-P681R and D950N promote membrane fusion, Spike-P681R enhances spike cleavage, but neither substitution affects pathogenicity in hamsters	124
Trajectories of olfactory identification preceding incident mild cognitive impairment and dementia: a longitudinal study	121
High serum C-X-C motif chemokine ligand 10 (CXCL10) levels may be associated with new onset interstitial lung disease in patients with systemic sclerosis: evidence from observational, clinical, transc	120
Do interventions for mood improve inflammatory biomarkers in inflammatory bowel disease?: a systematic review and meta-analysis	119
Circular-SWAT for deep learning based diagnostic classification of Alzheimer's disease: application to metabolome data	116
Prospective multicenter evaluation of real time PCR Kit prototype for early diagnosis of congenital Chagas disease	114
Neolithic introgression of IL23R-related protection against chronic inflammatory bowel diseases in modern Europeans	113
Phase 2, randomized, double-blind, placebo-controlled multi-center trial of the clinical and biological effects of anti-CD14 treatment in hospitalized patients with COVID-19 pneumonia	113
Bi-allelic LAMP3 variants in childhood interstitial lung disease: a surfactant-related disease	111
Machine learning detection of heteroresistance in Escherichia coli	108
An epigenetic signature to fight COVID-19	107
Association of body composition with neuroimaging biomarkers and cognitive function; a population-based study of 70-year-olds	106
T cell response against SARS-CoV-2 persists after one year in patients surviving severe COVID-19	106
Spatial and single-cell colocalisation analysis reveals MDK-mediated immunosuppressive environment with regulatory T cells in colorectal carcinogenesis	105
Different oxytocin and corticotropin-releasing hormone system changes in bipolar disorder and major depressive disorder patients	104
Neurochemical signs of astrocytic and neuronal injury in acute COVID-19 normalizes during long-term follow-up	103
Local fistula injection of allogeneic human amnion epithelial cells is safe and well tolerated in patients with refractory complex perianal Crohn's disease: a phase I open label study with long-term f	102
Patient-derived melanoma organoid models facilitate the assessment of immunotherapies	100
Daily variation in blood glucose levels during continuous enteral nutrition in patients on the intensive care unit: a retrospective observational study	100
Super-resolution ultrasound imaging reveals temporal cerebrovascular changes with disease progression in female 5×FAD mouse model of Alzheimer's disease: correlation with pathological impairments	99
The gene environment aetiology of freezing and its relationship with internalizing symptoms during adolescence	98
Affordable blood culture systems from China: in vitro evaluation for use in resource-limited settings	96
Endotrophin is associated with chronic multimorbidity and all-cause mortality in a cohort of elderly women	94
Effect of intra-partum azithromycin on the development of the infant nasopharyngeal microbiota: A post hoc analysis of a double-blind randomized trial	94
Same-day confirmation of infection and antimicrobial susceptibility profiling using flow cytometry	94
A pancreatic cancer risk prediction model (Prism) developed and validated on large-scale US clinical data	93
A custom-made mouthguard reduces head acceleration during soccer heading and prevents acute electrophysiological and cognitive changes in amateur male players	92
NR4A3 prevents diabetes induced atrial cardiomyopathy by maintaining mitochondrial energy metabolism and reducing oxidative stress	92
Adults with Plasmodium falciparum malaria have higher magnitude and quality of circulating T-follicular helper cells compared to children	92
Selective emergence of antibody-secreting cells in the multiple sclerosis brain	92
Clinical and genetic characteristics of a large international cohort of individuals with rare NR5A1/SF-1 variants of sex development	88
Adenoviral vectored vaccination protects against Crimean-Congo Haemorrhagic Fever disease in a lethal challenge model	88
Desulfovibrio desulfuricans and its derived metabolites confer resistance to FOLFOX through METTL3	88
Genetic landscape of a large cohort of Primary Ovarian Insufficiency: New genes and pathways and implications for personalized medicine	87
Increased viral variants in children and young adults with impaired humoral immunity and persistent SARS-CoV-2 infection: A consecutive case series	87
Alzheimer's disease protease-containing plasma extracellular vesicles transfer to the hippocampus via the choroid plexus	86
Interim results from a phase I randomized, placebo-controlled trial of novel SARS-CoV-2 beta variant receptor-binding domain recombinant protein and mRNA vaccines as a 4th dose booster	86
Development of a translational inflammation panel for the quantification of cerebrospinal fluid Pterin, Tryptophan-Kynurenine and Nitric oxide pathway metabolites	85
Hypoxia activated HGF expression in pancreatic stellate cells confers resistance of pancreatic cancer cells to EGFR inhibition	83
NIR-II fluorescence-guided liver cancer surgery by a small molecular HDAC6 targeting probe	83
Genome-wide interaction study of dietary intake of fibre, fruits, and vegetables with risk of colorectal cancer	82
TNAP is a novel regulator of cardiac fibrosis after myocardial infarction by mediating TGF-β/Smads and ERK1/2 signaling pathways	81
Molecular imaging in experimental pulmonary fibrosis reveals that nintedanib unexpectedly modulates CCR2 immune cell infiltration	81
Circadian rhythms in haematological malignancies: therapeutic potential and personalised interventions	81

Molecular modelling of the FOXO4-TP53 interaction to design senolytic peptides for the elimination of senescent cancer cells	81
Can the level of copper in the hippocampus witness type-II diabetes versus Alzheimer's disease?	80
Reduced white matter microstructural integrity in prediabetes: Is early glucose dysmetabolism the culprit?	79
Shifting microbiomes: pathobionts hiding in our guts	79
The distinct genetic features of pancreatic cancer in Chinese population	79
A comprehensive evaluation of full-spectrum cell-free RNAs highlights cell-free RNA fragments for early-stage hepatocellular carcinoma detection	79