OOIR: Observatory of International Research

Papers

(The H4-Index of eBioMedicine is 82. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)

Article	Citations
Corrigendum to “Single-cell RNA transcriptomics in mice reveals embryonic origin of fibrosis due to maternal obesity” [eBioMedicine 109(2024) 105421]	524
Corrigendum to “The significance of recurrent de novo amino acid substitutions that emerged during chronic SARS-CoV-2 infection: an observational study” [eBioMedicine, 2024;107:105273]	458
Authors' reply to letter regarding “Inflammaging links life's essential 8 to white matter brain aging”	354
Trajectories of olfactory identification preceding incident mild cognitive impairment and dementia: a longitudinal study	353
Neolithic introgression of IL23R-related protection against chronic inflammatory bowel diseases in modern Europeans	342
A computational framework to improve cross-platform implementation of transcriptomics signatures	310
Modeling of cancer-related body-wide effects identifies LTB4 as a diagnostic biomarker for pancreatic cancer	270
Exploring electroencephalographic chronic pain biomarkers: a mega-analysis	264
Affordable blood culture systems from China: in vitro evaluation for use in resource-limited settings	238
Precision diagnostic approach to predict 5-year risk for microvascular complications in type 1 diabetes	231
Elevated hippocampal copper in cases of type 2 diabetes	229
Diphtheria's resurgence and the high cost of misinformation	225
Association of body composition with neuroimaging biomarkers and cognitive function; a population-based study of 70-year-olds	222
Using gene-environment interactions to explore pathways for colorectal cancer risk	216
The anti-leprosy drug clofazimine reduces polyQ toxicity through activation of PPARγ	211
Mechanotransduction as a therapeutic target for brain tumours	208
Somatic hypermutation shapes the viral escape profile of SARS-CoV-2 neutralising antibodies	194
High level of plasma TILRR protein is associated with faster HIV seroconversion	190
T cell response against SARS-CoV-2 persists after one year in patients surviving severe COVID-19	189
A multiple sclerosis patient-oriented multiomics analysis tells us where to go next: Commentary for: “Alterations of host-gut microbiome interactions in multiple sclerosis”	184
Ebola-Detect: A differential serodiagnostic assay for Ebola virus infections and surveillance in the presence of vaccine-induced antibodies	176
Hypoxia activated HGF expression in pancreatic stellate cells confers resistance of pancreatic cancer cells to EGFR inhibition	172
Erratum to “Tumor cells hijack enteric glia to activate colon cancer stem cells and stimulate tumorigenesis” [EBioMedicine 49 (2019) 172–188]	156
Multifaceted autoimmunity: new challenges and new approaches	152
Phase 2a/b randomised placebo-controlled dose-escalation trial of triheptanoin for ataxia-telangiectasia: treating mitochondrial dysfunction with anaplerosis	148

Contributions of inherited mtDNA to longevity: evidence from extended pedigrees with 176 million kinship pairs	148
Machine learning detection of heteroresistance in Escherichia coli	144
Dilated Virchow Robin spaces in multiple sclerosis – a generalised marker of disease?	140
Evaluation of pre-diagnostic blood protein measurements for predicting survival after lung cancer diagnosis	139
The gene environment aetiology of freezing and its relationship with internalizing symptoms during adolescence	138
Daily variation in blood glucose levels during continuous enteral nutrition in patients on the intensive care unit: a retrospective observational study	129
Corrigendum to “PTGER3 induces ovary tumorigenesis and confers resistance to cisplatin therapy through up-regulation Ras-MAPK/Erk-ETS1-ELK1/CFTR1 axis” [EBioMedicine 40 (2019) 290-304]	128
Adults with Plasmodium falciparum malaria have higher magnitude and quality of circulating T-follicular helper cells compared to children	127
Alzheimer's disease protease-containing plasma extracellular vesicles transfer to the hippocampus via the choroid plexus	126
Next-gen spinal cord injury clinical trials: lessons learned and opportunities for future success	126
Same-day confirmation of infection and antimicrobial susceptibility profiling using flow cytometry	121
Phase 2, randomized, double-blind, placebo-controlled multi-center trial of the clinical and biological effects of anti-CD14 treatment in hospitalized patients with COVID-19 pneumonia	121
Corrigendum to “Pro-dopaminergic pharmacological interventions for anhedonia in depression: a living systematic review and network meta-analysis of human and animal studies”, EBioMedicine. 2025 Nov;12	118
A custom-made mouthguard reduces head acceleration during soccer heading and prevents acute electrophysiological and cognitive changes in amateur male players	117
Sex-specific interaction effects of Syntaxin 1A coexpression network and childhood trauma on adult depressive symptoms	116
Quantitative stiffness assessment of cardiac grafts using ultrasound in a porcine model: A tissue biomarker for heart transplantation	116
Effect of intra-partum azithromycin on the development of the infant nasopharyngeal microbiota: A post hoc analysis of a double-blind randomized trial	115
Probiotics counteract hepatic steatosis caused by ketogenic diet and upregulate AMPK signaling in a model of infantile epilepsy	114
A pancreatic cancer risk prediction model (Prism) developed and validated on large-scale US clinical data	111
α-Synuclein seed amplification assay positivity beyond synucleinopathies	111
Super-resolution ultrasound imaging reveals temporal cerebrovascular changes with disease progression in female 5×FAD mouse model of Alzheimer's disease: correlation with pathological impairments	110
Physical inactivity exacerbates pathologic inflammatory signalling at the single cell level in patients with systemic lupus	110
Desulfovibrio desulfuricans and its derived metabolites confer resistance to FOLFOX through METTL3	109
Mid- and late-life cardiovascular health indicators and changes in biological ageing Markers; a multi-cohort study	108
Imaging brain development in a KCNQ2-developmental and epileptic encephalopathy mouse model: identifying early biomarkers for functional and structural brain changes	108
Local fistula injection of allogeneic human amnion epithelial cells is safe and well tolerated in patients with refractory complex perianal Crohn's disease: a phase I open label study with long-term f	108
Glucose levels are associated with mood, but the association is mediated by ratings of metabolic state	107
Genome-wide interaction study of dietary intake of fibre, fruits, and vegetables with risk of colorectal cancer	104
Long-term safety and immunogenicity of an MF59-adjuvanted spike glycoprotein-clamp vaccine for SARS-CoV-2 in adults aged 18–55 years or ≥56 years: 12-month results from a randomised, double-blind, pla	103
Development of a translational inflammation panel for the quantification of cerebrospinal fluid Pterin, Tryptophan-Kynurenine and Nitric oxide pathway metabolites	100
Spatial and single-cell colocalisation analysis reveals MDK-mediated immunosuppressive environment with regulatory T cells in colorectal carcinogenesis	99
Interim results from a phase I randomized, placebo-controlled trial of novel SARS-CoV-2 beta variant receptor-binding domain recombinant protein and mRNA vaccines as a 4th dose booster	99
Clinical and genetic characteristics of a large international cohort of individuals with rare NR5A1/SF-1 variants of sex development	96
Association between wearable sensor signals and expected hormonal changes in pregnancy	96
Patient-derived melanoma organoid models facilitate the assessment of immunotherapies	95
Longitudinal effects of SARS-CoV-2 breakthrough infection on imprinting of neutralizing antibody responses	95
A comprehensive assessment of the association between common drugs and psychiatric disorders using Mendelian randomization and real-world pharmacovigilance database	94
Adenoviral vectored vaccination protects against Crimean-Congo Haemorrhagic Fever disease in a lethal challenge model	93
Different oxytocin and corticotropin-releasing hormone system changes in bipolar disorder and major depressive disorder patients	92
Gut microbiome and atrial fibrillation—results from a large population-based study	91
Bi-allelic LAMP3 variants in childhood interstitial lung disease: a surfactant-related disease	90
NR4A3 prevents diabetes induced atrial cardiomyopathy by maintaining mitochondrial energy metabolism and reducing oxidative stress	89
Genetic landscape of a large cohort of Primary Ovarian Insufficiency: New genes and pathways and implications for personalized medicine	89
In SARS-CoV-2 delta variants, Spike-P681R and D950N promote membrane fusion, Spike-P681R enhances spike cleavage, but neither substitution affects pathogenicity in hamsters	89
Do interventions for mood improve inflammatory biomarkers in inflammatory bowel disease?: a systematic review and meta-analysis	89
High serum C-X-C motif chemokine ligand 10 (CXCL10) levels may be associated with new onset interstitial lung disease in patients with systemic sclerosis: evidence from observational, clinical, transc	89
NIR-II fluorescence-guided liver cancer surgery by a small molecular HDAC6 targeting probe	88
Forever chemicals: the persistent effects of perfluoroalkyl and polyfluoroalkyl substances on human health	85
Circular-SWAT for deep learning based diagnostic classification of Alzheimer's disease: application to metabolome data	85
Selective emergence of antibody-secreting cells in the multiple sclerosis brain	85

Integrating artificial intelligence-based epitope prediction in a SARS-CoV-2 antibody discovery pipeline: caution is warranted	84
KCNQ2 R144 variants cause neurodevelopmental disability with language impairment and autistic features without neonatal seizures through a gain-of-function mechanism	84
Exploratory multi-omics analysis reveals host-microbe interactions associated with disease severity in psoriatic skin	84
Towards the molecular era of discriminating multiple lung cancers	84
Transcript levels in plasma contribute substantial predictive value as potential Alzheimer's disease biomarkers in African Americans	84
Plasma epoxyeicosatrienoic acids and diabetes-related cardiovascular disease: The cardiovascular health study	83
Targeting androgen receptor and the variants by an orally bioavailable Proteolysis Targeting Chimeras compound in castration resistant prostate cancer	82