Cellular and Molecular Gastroenterology and Hepatology

Article	Citations
Can Psyllium Alleviate Colitis?	143
Cover - DR3 Maintains ZO1 Expression in Intestinal Epithelia	69
Contents	61
Cover - Crohn's Disease: Spotlight on the Mesenteric Lymph Node Immune Response	60
Editorial Board	59
Heart-of-Glass: A Regulator at the Heart of Liver Morphogenesis and Metabolic Zonation	59
Retinoblastoma-binding Protein 9 Suppresses Intestinal Inflammation and Inflammation-induced Tumorigenesis in Mice	57
Reply	57
Development of Human Gut Organoids With Resident Tissue Macrophages as a Model of Intestinal Immune Responses	55
Antagonizing STK25 Signaling Suppresses the Development of Hepatocellular Carcinoma Through Targeting Metabolic, Inflammatory, and Pro-Oncogenic Pathways	50
Cellular Interactions and Crosstalk Facilitating Biliary Fibrosis in Cholestasis	47
Decoding the Ability of Helicobacter pylori to Evade Immune Recognition and Cause Disease	46
Beyond Regulation of Acid Secretion: A Novel Role for Histamine in Gastric Macrophage Differentiation and Function	45
PDK4 Inhibition Attenuates Colitis	44
Editorial Board	43
DDW 2022: Activities and Interests of the AGA Institute Council	42
Elsewhere in the AGA Journals	42
Bile Salts by the Back Road	41
Cyclin-dependent Kinase 9 as a Potential Target for Anti-TNF-resistant Inflammatory Bowel Disease	40
Cover - CDKN2A/p16 and KRAS Synergize in Barrett’s Esophagus Dysplasia	39
Bacterial Sphingolipids Exacerbate Colitis by Inhibiting ILC3-derived IL-22 Production	39
Autophagy Regulates Esophageal Epithelial Renewal	39
Activation of Proneuronal Transcription Factor Ascl1 in Maternal Liver Ensures a Healthy Pregnancy	38
TOB1 Blocks Intestinal Mucosal Inflammation Through Inducing ID2-Mediated Suppression of Th1/Th17 Cell Immune Responses in IBD	36
Wild-type APC Influences the Severity of Familial Adenomatous Polyposis	36

NRF2 Controls the Competitive Fitness of Squamous Epithelial Cells in the Mouse Esophagus	34
HBV X Protein Induces Degradation of UBXN7, a Novel Negative Regulator of NF-κB Signaling, to Promote HBV Replication	34
UBCH5 Family Members Differentially Impact Stabilization of Mutant p53 via RNF128 Iso1 During Barrett’s Progression to Esophageal Adenocarcinoma	33
Inhibition of the SLC35B2–TPST2 Axis of Tyrosine Sulfation Attenuates the Growth and Metastasis of Pancreatic Ductal Adenocarcinom	33
Pioneer Factor Foxa2 Mediates Chromatin Conformation Changes for Activation of Bile Acid Targets of FXR	31
New Immune Role for Axin1 in Colon Cancer Suppression	31
A Protein Complex of Liver Origin Activates a Pro-inflammatory Program That Drives Hepatic and Intestinal Injury in Alcohol-Associated Liver Disease	30
ZEB1 Transcriptionally Activates PHGDH to Facilitate Carcinogenesis and Progression of HCC	29
Myenteric Neurons Do Not Replicate in Small Intestine Under Normal Physiological Conditions in Adult Mouse	29
Unravelling the Matrix in Crohn’s Disease	29
Intrinsic STING Switches off Pathogenetic Programs of Th1 Cells to Inhibit Colitis	29
Fatty Acid Ethyl Ethers: New Modulators of Acute Ethanol-Mediated Hepatotoxicity?	28
Lactobacillus rhamnosus GG Stimulates Dietary Tryptophan-Dependent Production of Barrier-Protecting Methylnicotinamide	27
Circ-CCT2 Activates Wnt/β-catenin Signaling to Facilitate Hepatoblastoma Development by Stabilizing PTBP1 mRNA	27
Replication Efficiency of SARS-CoV-2 Omicron Subvariants BA.2.75, BA.5, and XBB.1 in Human Mini-Gut Organoids	27
Microbial-derived Urolithin A Targets GLS1 to Inhibit Glutaminolysis and Attenuate Cirrhotic Portal Hypertension	26
Glucagon-Like Peptide-2 Stimulates S-Phase Entry of Intestinal Lgr5+ Stem Cells	26
Inhibition of Abelson Tyrosine-Protein Kinase 2 Suppresses the Development of Alcohol-Associated Liver Disease by Decreasing PPARgamma Expression	26
Location Matters: Mitochondrial Arginase 2 as a Treatment for Metabolic Disease?	26
The miR-23b/27b/24-1 Cluster Inhibits Hepatic Fibrosis by Inactivating Hepatic Stellate Cells	26
Regulation of Liver Regeneration by Hepatocyte O-GlcNAcylation in Mice	26
A High-Fat Diet Activates the BAs-FXR Axis and Triggers Cancer-Associated Fibroblast Properties in the Colon	26
BET Inhibition Rescues Acinar-Ductal-Metaplasia and Ciliogenesis and Ameliorates Chronic Pancreatitis-Driven Changes in Mice With Loss of the Polarity Protein Par3	26
H3K27me3 Demethylases Maintain the Transcriptional and Epigenomic Landscape of the Intestinal Epithelium	25
Ptpn2: A Critical Regulator of Paneth Cell Homeostasis	25
Autophagy-Related Activation of Hepatic Stellate Cells Reduces Cellular miR-29a by Promoting Its Vesicular Secretion	25
Mucosal-Associated Invariant T Cells in the Digestive System: Defender or Destroyer?	24
LKB1 in Intestinal Epithelial Cells Regulates Bile Acid Metabolism by Modulating FGF15/19 Production	24
AXL Expression on Homeostatic Resident Liver Macrophages Is Reduced in Cirrhosis Following GAS6 Production by Hepatic Stellate Cells	23
Osr1 Is a Critical Regulator of Macrophage Polarization in NASH Progression	23
Glucose Sensing in the Hepatic Portal Vein and Its Role in Food Intake and Reward	23
Editorial Board	23
Osr1 Regulates Macrophage-mediated Liver Inflammation in Nonalcoholic Fatty Liver Disease Progression	23
Single-cell Profiling of Intrahepatic Immune Cells Reveals an Expansion of Tissue-resident Cytotoxic CD4+ T Lymphocyte Subset Associated With Pathogenesis of Alcoholic-associated Liver Diseases	23
Deficiency of the Two-Pore Potassium Channel KCNK9 Impairs Intestinal Epithelial Cell Survival and Aggravates Dextran Sodium Sulfate-Induced Colitis	23
Toll-like Receptor 9 Promotes Initiation of Gastric Tumorigenesis by Augmenting Inflammation and Cellular Proliferation	23
Gut Microbiota Remodeling and Intestinal Adaptation to Lipid Malabsorption After Enteroendocrine Cell Loss in Adult Mice	23
Cover 1 - Mechanistic Insights Into Colonic Motor Patterns	22
A Nutraceutical Mechanistic Model Receives a Gut Check	22
Contents	22
PFKFB4 Is a Metabolic Driver of HCC Progression and Chemoresistance Through ROS Mitigation	22
Tofacitinib-Induced Modulation of Intestinal Adaptive and Innate Immunity and Factors Driving Cellular and Systemic Pharmacokinetics	22
Contents	22
Sex Differences in Genomic Features of Hepatitis B–Associated Hepatocellular Carcinoma With Distinct Antitumor Immunity	22
The Effect of In Utero Exposure to Maternal Inflammatory Bowel Disease and Immunomodulators on Infant Immune System Development and Function	21
Neutrophil Extracellular Traps Enhance Liver Inflammation and Fibrin Deposition in Fulminant Viral Hepatitis	21
Human Cytomegalovirus-IE2 Affects Embryonic Liver Development and Survival in Transgenic Mouse	21
Editorial Board	21
Role of ICAM-1 in the Adhesion of T Cells to Enteric Glia: Perspectives in the Formation of Plexitis in Crohn’s Disease	20
All Good Things Come to an End: 5 Years at the Helm of CMGH	20

Pathophysiological Roles of Ductular Reaction in Liver Inflammation and Hepatic Fibrogenesis	20
Single-Cell Transcriptomics of Liver Cancer: Hype or Insights?	19
A Novel CRISPR/Cas9-mediated Mouse Model of Colon Carcinogenesis	19
Elevated Protein Kinase A Activity in Stomach Mesenchyme Disrupts Mesenchymal-epithelial Crosstalk and Induces Preneoplasia	19
Interindividual Variation in Gut Nitrergic Neuron Density Is Regulated By GDNF Levels and ETV1	19
Bile Acid Induced Inflammation and the Role of β-Catenin	18
XBP1 Facilitating NF-κB-p65 Nuclear Translocation Promotes Macrophage-Originated Sterile Inflammation Via Regulating MT2 Transcription in the Ischemia/Reperfusion Liver	18
The Immune Underpinnings of Barrett’s-Associated Adenocarcinogenesis: a Retrial of Nefarious Immunologic Co-Conspirators	18
Inhibition of EZH2 Reduces Aging-Related Decline in Interstitial Cells of Cajal of the Mouse Stomach	18
Cover - Esophageal Eosinophils Protect From Invasive Squamous Neoplasia	18
Interferon Signaling Alters Epithelial Function in Eosinophilic Esophagitis	18
Th2 Cell Activation in Chronic Liver Disease Is Driven by Local IL33 and Contributes to IL13-Dependent Fibrogenesis	18
Altered catecholamine stimulated adipose lipolysis contributes to hepatic steatosis in Pnpla3I148M mice	17
Deciphering Brain Metastasis Stem Cell Properties From Colorectal Cancer Highlights Specific Stemness Signature and Shared Molecular Features	17
Mouse Models for Chronic Hepatitis B: Old Challenges, Novel Approaches	17
Inhibition of Pyruvate Dehydrogenase Kinase 4 in CD4+ T Cells Ameliorates Intestinal Inflammation	17
Sorafenib Promotes Treg Cell Differentiation To Compromise Its Efficacy via VEGFR/AKT/Foxo1 Signaling in Hepatocellular Carcinoma	17
Cover	16
COVID-19 Diarrhea Is Inflammatory, Caused by Direct Viral Effects Plus Major Role of Virus-induced Cytokines	16
T Cell Repertoire Homogeneity and Blood-Gut Overlap in Patients With Inflammatory Bowel Disease	16
Cover - Hepatostellate organoid differentiated from patient-derived iPS cells	16
Types of Neurons in the Human Colonic Myenteric Plexus Identified by Multilayer Immunohistochemical Coding	16
In Vitro Models for the Study of Liver Biology and Diseases: Advances and Limitations	16
Corrections	16
On the Origin of Pancreatic Cancer: Molecular Tumor Subtypes in Perspective of Exocrine Cell Plasticity	16
Gut-innervating TRPV1+ Neurons Drive Chronic Visceral Pain via Microglial P2Y12 Receptor	15
In Vivo Genome-Wide CRISPR Activation Screening Identifies Functionally Important Long Noncoding RNAs in Hepatocellular Carcinoma	15
Fueling HCC Dynamics: Interplay Between Tumor Microenvironment and Tumor Initiating Cells	15
Vasoactive Intestinal Polypeptide Plays a Key Role in the Microbial-Neuroimmune Control of Intestinal Motility	15
Heterozygous Spink1 Deficiency Promotes Trypsin-dependent Chronic Pancreatitis in Mice	15
Distal Fecal Wash: Intestinal Liquid Biopsy?	15
Suppression of Hepatocellular Carcinoma by Deletion of SIRT2 in Hepatocytes via Elevated C/EBPβ/GADD45γ	15
Rapid Research, High Impact: CMGH’s Short-Form Initiative	15
The relationship between CSF1R signaling, monocyte-macrophage differentiation and susceptibility to inflammatory bowel disease.	15
Enteric Neuromics: How High-Throughput “Omics” Deepens Our Understanding of Enteric Nervous System Genetic Architecture	15
Alterations in Cytoskeleton and Mitochondria in the Development and Reversal of Steatosis in Human Hepatocytes	15
Oxaliplatin-Resistant Hepatocellular Carcinoma Drives Immune Evasion Through PD-L1 Up-Regulation and PMN-Singular Recruitment	15
Cortactin Facilitates Malignant Transformation of Dysplastic Cells in Gastric Cancer Development	15
Bone Loss in Intestinal Inflammation Disease Yields to Osteoclastogenesis Inhibition	14
Editorial Board	14
Editorial Board	14
NCOA5 Haploinsufficiency in Myeloid-Lineage Cells Sufficiently Causes Nonalcoholic Steatohepatitis and Hepatocellular Carcinoma	14
Editorial Board	14
Prolonged Administration of Melatonin Ameliorates Liver Phenotypes in Cholestatic Murine Model	14
Distal Fecal Wash Host Transcriptomics Identifies Inflammation Throughout the Colon and Terminal Ileum	14
Cover 1 - Melatonin Improves Primary Sclerosing Cholangitis in Mice	14
Gut Microbiota-Derived Glutamine Attenuates Liver Ischemia/Reperfusion Injury via Macrophage Metabolic Reprogramming	14
Liver-specific Bcl3 Knockout Alleviates Acetaminophen-induced Liver Injury by Activating Nrf2 Pathway in Male Mice	14
Interplay Between Liver Type 1 Innate Lymphoid Cells and NK Cells Drives the Development of Alcoholic Steatohepatitis	14
Contents	13
Editorial Board	13
SLC26A3 (DRA, the Congenital Chloride Diarrhea Gene): A Novel Therapeutic Target for Diarrheal Diseases	13
Editorial Board	13
The STING That Tames Pro-inflammatory T-cells	13
Cover - Thrombospondin-1 Affects Migrating Fibroblasts in Colorectal Cancer	13
The Great Reset: A “Tuft” Journey Towards Tumorigenesis	13
Insulin-Like Growth Factor1 Preserves Gastric Pacemaker Cells and Motor Function in Aging via ERK1/2 Activation	13
Oral Supplementation of Phosphatidylcholine Attenuates the Onset of a Diet-Induced Metabolic Dysfunction–Associated Steatohepatitis in Female C57BL/6J Mice	13
Sex Matters: From Bile Acid Metabolism to Liver Cancer	13
Prostaglandin E2 and Akt Promote Stemness in Apc Mutant Dclk1+ Cells to Give Rise to Colitis-associated Cancer	13
Long-term Temporal Stability of Peripheral Blood DNA Methylation Profiles in Patients With Inflammatory Bowel Disease	12
The Proteomic Signature of Tissue Remodeling in Chronic Intestinal Inflammation	12
Genome-Wide Methylation Profiling in 229 Patients With Crohn’s Disease Requiring Intestinal Resection: Epigenetic Analysis of the Trial of Prevention of Post-operative Crohn’s Disease (TOPPIC)	12
PFKFB3-mediated Pro-glycolytic Shift in Hepatocellular Carcinoma Proliferation	12
PDGFRα+ Interstitial Cells are Effector Cells of PACAP Signaling in Mouse and Human Colon	12
Breaking Down the Pain Pathway: Bacterial Proteases Activate Nociceptors to Cause Pain	12
Contents	12
HIRA in Hepatitis B Virus Minichromosome Regulation: Another Piece of the Puzzle	12
Something to mTORC About in NASH	12
Rebuttal to: Liver Steatosis is a Driving Factor of Inflammation	12
Improving Gastric Motility in Aging Through EZH2 Inhibition and Preservation of Interstitial Cells of Cajal	12
Stromal Niche Signals That Orchestrate Intestinal Regeneration	12
Enteroendocrine Cell Loss Drives Small Intestinal Hypomotility in Colitis	11
Hepatic Reduction in Cholesterol 25-Hydroxylase Aggravates Diet-induced Steatosis	11
Mrgprb2-dependent Mast Cell Activation Plays a Crucial Role in Acute Colitis	11
STAT3 is Activated by CTGF-mediated Tumor-stroma Cross Talk to Promote HCC Progression	11
The Microbiota Conducts the Vasoactive Intestinal Polypeptide Orchestra in the Small Intestine	11
Downregulation of V-ATPase V0 Sector Induces Microvillus Atrophy Independently of Apical Trafficking in the Mammalian Intestine	11
WNT2B Deficiency Causes Enhanced Susceptibility to Colitis Due to Increased Inflammatory Cytokine Production	11
Scattered Crypt Intestinal Epithelial Cell Apoptosis Induces Necrotizing Enterocolitis Via Intricate Mechanisms	11

Pharmacologic Antagonization of Cannabinoid Receptor 1 Improves Cholestasis in Abcb4 Mice	11
Dysfunction of ATP7B Splicing Variant Caused by Enhanced Interaction With COMMD1 in Wilson Disease	11
Glia Maturation Factor-β Supports Liver Regeneration by Remodeling Actin Network to Enhance STAT3 Proliferative Signals	10
Single-Cell Analysis Reveals Unexpected Cellular Changes and Transposon Expression Signatures in the Colonic Epithelium of Treatment-Naïve Adult Crohn’s Disease Patients	10
Surgery for Crohn’s Disease Is Associated With a Dysbiotic Microbiome and Metabolome: Results From Two Prospective Cohorts	10
The Role of Microbiota in Gastrointestinal Cancer and Cancer Treatment: Chance or Curse?	10
Hypoxia Primes Human ISCs for Interleukin-Dependent Rescue of Stem Cell Activity	10
Rome III Criteria Capture Higher Irritable Bowel Syndrome SNP-Heritability and Highlight a Novel Genetic Link With Cardiovascular Traits	10
IFNγ and CTLA-4 Drive Hepatic CD4 T-Cell Tolerance and Protection From Autoimmunity in Mice	10
The Interleukin 33–T Helper 2 Cell Axis Promotes Human Liver Fibrosis	10
C-Reactive Protein Protects Against Acetaminophen-Induced Liver Injury by Preventing Complement Overactivation	10
Novel Fat Taste Receptor Agonists Curtail Progressive Weight Gain in Obese Male Mice	10
Cover	10
Hydroxynonenal Causes Hepatocyte Death by Disrupting Lysosomal Integrity in Nonalcoholic Steatohepatitis	10
Macrophage COX2 Mediates Efferocytosis, Resolution Reprogramming, and Intestinal Epithelial Repair	10
Nrf2 Mutation/Activation Is Dispensable for the Development of Chemically Induced Mouse HCC	10
Shp2 Deficiency in Kupffer Cells and Hepatocytes Aggravates Hepatocarcinogenesis by Recruiting Non-Kupffer Macrophages	10
Survival of Stem Cells and Progenitors in the Intestine Is Regulated by LPA5-Dependent Signaling	10
Neurotensin Regulates Proliferation and Stem Cell Function in the Small Intestine in a Nutrient-Dependent Manner	10
Disruption to tRNA Modification by Queuine Contributes to Inflammatory Bowel Disease	10
Sex Dimorphic Effects of Bile Acid Metabolism in Liver Cancer in Mice	10
NF-κB Inducing Kinase Attenuates Colorectal Cancer by Regulating Noncanonical NF-κB Mediated Colonic Epithelial Cell Regeneration	10
Additive Effect of CD73 Inhibitor in Colorectal Cancer Treatment With CDK4/6 Inhibitor Through Regulation of PD-L1	10
RBPJ Deficiency Sensitizes Pancreatic Acinar Cells to KRAS-Mediated Pancreatic Intraepithelial Neoplasia Initiation	10