Cellular and Molecular Gastroenterology and Hepatology

Article	Citations
Cover	133
Should I Stay or Should I Go – ERK as Control Lever in Hepatocyte Expansion	131
NRF2 Controls the Competitive Fitness of Squamous Epithelial Cells in the Mouse Esophagus	111
New Immune Role for Axin1 in Colon Cancer Suppression	90
Ptpn2: A Critical Regulator of Paneth Cell Homeostasis	89
Mucosal-Associated Invariant T Cells in the Digestive System: Defender or Destroyer?	86
Contents	86
Macrophage Nogo-B Drives Liver Fibrosis	85
Interindividual Variation in Gut Nitrergic Neuron Density Is Regulated By GDNF Levels and ETV1	76
Pathophysiological Roles of Ductular Reaction in Liver Inflammation and Hepatic Fibrogenesis	74
T Cell Repertoire Homogeneity and Blood-Gut Overlap in Patients With Inflammatory Bowel Disease	73
Loss of Brg1 and Pten in Pancreatic Ductal Cells Forms Intraductal Tubulopapillary Neoplasm via the YAP/TAZ Pathway	66
Targeting Ferroptosis Restores the Antiviral Activity of CD8+ T Cells During Chronic Hepatitis B Virus Infection	61
Bile Acid Detergency as Determinant of Liver Pathology in a Humanized Mouse Model of Progressive Familial Intrahepatic Cholestasis Type 3	60
Cilk1 Is Essential for Mesenchymal Cilia Maintenance and Epithelial-mesenchymal Crosstalk in Intestinal Villus Morphogenesis	60
Factors to Consider in Gut Microbiota Interactions With the Enteric Nervous System—What You Look for Is What You Get	59
Autophagy Regulates Esophageal Epithelial Renewal	59
Location Matters: Mitochondrial Arginase 2 as a Treatment for Metabolic Disease?	59
Cover	58
Modulating Bile Acid Metabolism: The Role of Blautia coccoides in Acute Pancreatitis	52
Contents	49
Liver-specific Bcl3 Knockout Alleviates Acetaminophen-induced Liver Injury by Activating Nrf2 Pathway in Male Mice	49
Serum Amyloid A Protein Promotes Fibrolysis and Recovery Following Alcohol Withdrawal	48
Cover	48
The Placode Lineage Contributes to the Enteric Nervous System: A Caution for Cell Transplantation Therapy for Hirschsprung Disease	46

RBPJ Deficiency Sensitizes Pancreatic Acinar Cells to KRAS-Mediated Pancreatic Intraepithelial Neoplasia Initiation	45
PFKFB3-mediated Pro-glycolytic Shift in Hepatocellular Carcinoma Proliferation	44
Long-term Temporal Stability of Peripheral Blood DNA Methylation Profiles in Patients With Inflammatory Bowel Disease	41
NF-κB Inducing Kinase Attenuates Colorectal Cancer by Regulating Noncanonical NF-κB Mediated Colonic Epithelial Cell Regeneration	40
A Dual-compartment Scaffolding Role for Receptor for Activate C Kinase 1 in Hepatic Glucagon Signaling and Gluconeogenesis	39
Role of Nox4 in Mitigating Inflammation and Fibrosis in Dextran Sulfate Sodium–Induced Colitis	39
Stratifin Is Necessary for Spasmolytic Polypeptide-Expressing Metaplasia Development After Acute Gastric Injury	36
Bacteroides acidifaciens Attenuates Concanavalin A–Induced Liver Injury by Remodeling Bile Acids to Suppress CD95-Mediated Hepatocyte Apoptosis via the Takeda G Protein-Coupled Receptor 5–FOSL1 Pathwa	36
Geranylgeranyl Pyrophosphate Promotes Hepatic Lipid Accumulation by Prenylation of Perilipin4	36
The Interplay of TGF-β1 and Cholesterol Orchestrating Hepatocyte Cell Fate, EMT, and Signals for HSC Activation	35
Cover	34
CREB Fuels Tumorigenesis in Alcoholic Pancreatitis	32
PFKFB4 Drives the Oncogenicity in TP53-Mutated Hepatocellular Carcinoma in a Phosphatase-Dependent Manner	31
Extrinsic Innervation of Myenteric Plexus of Human Large Intestine Via Colonic Nerves	31
Cover	30
Contents	29
Anti-prion Antibody Ameliorates Metabolic Dysfunction-associated Steatohepatitis in Mice	29
Editorial Board	29
Contents	29
Normalization of Cystic Fibrosis Immune System Reverses Intestinal Neutrophilic Inflammation and Significantly Improves the Survival of Cystic Fibrosis Mice	28
Ferroptosis: A Novel Target to Rescue CD8+ T Cells Against Hepatitis B Virus	28
Activation and Spatial Redistribution of RNA Splicing Factors Trigger Hepatic Regeneration	26
Adipokine C1q/Tumor Necrosis Factor- Related Protein 3 (CTRP3) Attenuates Intestinal Inflammation Via Sirtuin 1/NF-κB Signaling	25
CDKN2A-p16 Deletion and Activated KRASG12D Drive Barrett’s-Like Gland Hyperplasia-Metaplasia and Synergize in the Development of Dysplasia Precancer Lesions	25
In vivo CRISPR Activation Screening, a Powerful Tool to Discover Oncogenic Driver Genes in Hepatocellular Carcinoma	25
Continuous Activation of C/EBPβ Transcription Factor Prevents Fibrosis Resolution After Alcohol Cessation	25
Sonic Hedgehog and WNT Signaling Regulate a Positive Feedback Loop Between Intestinal Epithelial and Stromal Cells to Promote Epithelial Regeneration	24
Protocadherin 20 Is a POU Class 2 Homeobox 3 Target Gene Required for Proper Tuft Cell Microvillus Organization	24
Ablation of Sympathetic Nerve-β3 Adrenergic Receptor-mediated Adipose Tissue Lipolysis Attenuates Alcohol-induced Liver Injury in Mice	24
GDF15 Ameliorates Liver Fibrosis by Metabolic Reprogramming of Macrophages to Acquire Anti-Inflammatory Properties	23
Contents	23
Myosin Light Chain 9 Mediates Graft Fibrosis After Pediatric Liver Transplantation Through TLR4/MYD88/NF-κB Signaling	23
Editorial Board	23
Targeting Tumor Stroma in CMS4 Colorectal Cancer: Phospholamban Takes Center Stage	23
Editorial Board	23
KDM6A/B Demethylases in Gut Homeostasis	23
Siglec-H-/- Plasmacytoid Dendritic Cells Protect Against Acute Liver Injury by Suppressing IFN-γ/Th1 Response and Promoting IL-21+ CD4 T Cells	23
Selective Elimination of NRF2-Activated Cells by Competition With Neighboring Cells in the Esophageal Epithelium	22
When Liver Slices Meet Single-cell Technology	22
Androgen Enhances Aflatoxin-induced Genotoxicity and Inflammation to Liver Cancer in Male Hepatitis B Patients	22
Tofacitinib Mitigates the Increased SARS-CoV-2 Infection Susceptibility Caused by an IBD Risk Variant in the PTPN2 Gene	22
Calcium Channel α2δ1 is Essential for Pancreatic Tumor-Initiating Cells through Sequential Phosphorylation of PKM2	22
Acute Phase Response-driven Hepatic Niche Remodeling Promotes Fibrosis Resolution After Alcohol Cessation	22
Interplay Between Drug-Induced Liver Injury and Gut Microbiota: A Comprehensive Overview	21
MUC13 Cell Surface Mucin Limits Salmonella Typhimurium Infection by Protecting the Mucosal Epithelial Barrier	21
Microbial Players in Primary Sclerosing Cholangitis: Current Evidence and Concepts	21
The Protective Role of DDIT4 in Helicobacter pylori-induced Gastric Metaplasia Through Metabolic Regulation of Ferroptosis	21
Beyond the Alpha and Omega: Redefining the Peroxisome Proliferator–Activated Receptor α Gut–Liver Axis in Intestinal Failure–Associated Liver Disease	21
Enteral Feeding With Omega-3 Polyunsaturated Fatty Acids Mitigates Liver Injury Following Massive Intestinal Resection	21
Cancer-Associated Fibroblasts in Hepatocellular Carcinoma and Cholangiocarcinoma	21

Histamine Signaling Is Essential for Tissue Macrophage Differentiation and Suppression of Bacterial Overgrowth in the Stomach	20
Liver Traffic Jam: How Sinusoidal Congestion Rewires Macrophage Distribution via CXCL9	20
Increased Motility and Suppression of Ex Vivo–Expanded Regulatory T Cells Designed for Adoptive Transfer Therapy in Ulcerative Colitis	20
Fibroblast Activation Protein Activates Macrophages and Promotes Parenchymal Liver Inflammation and Fibrosis	20
Scaffolding Supports the Hippo	20
Cover	20
Innate Lymphoid Cells: New Culprits of Alcohol-Associated Steatohepatitis	20
Caffeine Limits Expansion of Apc-Deficient Clones in the Intestine by NOTUM Inhibition	20
From Muscle to Macrophage: An Anti-inflammatory Role for the Metabolite N-lactoyl-phenylalanine in Inflammatory Bowel Disease	19
Glycoprotein (GP)96 Is Essential for Maintaining Intestinal Epithelial Architecture by Supporting Its Self-Renewal Capacity	19
Correction	19
A Balancing Act: GRHL3 Limits WNT Signaling to Promote Tissue Homeostasis in the Esophageal Epithelium	19
Editorial Board	19
DNMT3B Alleviates Liver Steatosis Induced by Chronic Low-grade LPS via Inhibiting CIDEA Expression	19
Contents	19
Irritable Bowel Syndrome With Diarrhea in Pediatric Patients Is Associated With Type 2 and Type 9 T Cells in the Intestinal Mucosa	19
Interferon-γ Signaling in Eosinophilic Esophagitis Affects Epithelial Barrier Function and Programmed Cell Death	18
Loss of SQSTM1/p62 Induces Obesity and Exacerbates Alcohol-Induced Liver Injury in Aged Mice	18
Blockade of Hepatocyte PCSK9 Ameliorates Hepatic Ischemia-Reperfusion Injury by Promoting Pink1-Parkin–Mediated Mitophagy	18
Intrahepatic Exhausted Antiviral Immunity in an Immunocompetent Mouse Model of Chronic Hepatitis B	18
ΔNP63 Defines an Exocrine-committed Subset of Murine Pancreatic Progenitor Cells	18
Microbiota-dependent Formylated Peptide Receptor (Fpr1/2) Signaling Regulates Enteric Nervous System Development and Gastrointestinal Motility in Mice	18
Presence of Intact Hepatitis B Virions in Exosomes	18
Oxidized HMGB1 Adducts Unleash Inflammation in Alcohol-Associated Liver Disease	18
Congestion Enriches Intra-hepatic Macrophages Through Reverse Zonation of CXCL9 in Liver Sinusoidal Endothelial Cells	18
Elevated Triggering Receptor Expressed on Myeloid Cells 2 Expression in Tumor-Associated Macrophages Suppresses Cytotoxic T Cell Infiltration and Facilitates Immune Escape in Colorectal Cancer	18
Microbial Monotherapy With Leuconostoc sp LB-P8 Improves Inflammation and Fibrosis in Mouse Primary Sclerosing Cholangitis by Inhibiting Transforming Growth Factor β1/SMAD Signaling	17
CMGH: Evolving to Advance Gastroenterology and Hepatology Research	17
Actinomyces odontolyticus: From Carries to Colorectal Cancer	17
Genetic Ablation of C/EBPα-p300 Pathway Blocks Development of Obese Pregnancy Associated Liver Disorders in Offspring	17
Interleukin-13 Promotes Accumulation of Esophageal Epithelial Mitochondria With Translational Implications for Eosinophilic Esophagitis	17
Cover - Blocking BRP39 Alters the Course of Liver Inflammation	17
Myofibroblast-Driven Crohn’s Disease Fiber Stricture Fibrotic Microenvironment: High-Resolution Spatial Transcriptomic Analysis	17
A New Model of Gastric Pre-neoplasia Induced by Aberrant ADAR1-mediated Double-stranded RNA Signaling	17
Genetic Variation Between Small Bowel and Colon-Predominant Crohn's Disease	17
Correction	17
Telocyte Recruitment During the Emergence of a Metaplastic Niche in the Stomach	16
Epigenetic Rearrangements Driven by Enhancer of Zeste Homolog 2 Are Linked to Impaired Tissue Regeneration in Neonatal Necrotizing Enterocolitis	16
PKMζ, a Brain-specific PKCζ Isoform, is Required for Glycolysis and Myofibroblastic Activation of Hepatic Stellate Cells	16
Notch-Driven Cholangiocarcinogenesis Involves the Hippo Pathway Effector TAZ via METTL3-m6A-YTHDF1	16
Stress Granules as Molecular Echoes of Gut Inflammation	16
Colitis-Induced Small Intestinal Hypomotility Is Dependent on Enteroendocrine Cell Loss in Mice	16
Rethinking Immune Check Point Inhibitors Use in Liver Transplantation: Implications and Resistance	16
Vitamin D Receptor Activation Targets ROS-Mediated Crosstalk Between Autophagy and Apoptosis in Hepatocytes in Cholestasic Mice	16
Inducible POU Class 2 Homeobox 3 Expression in Human Intestinal Organoids as a Model of Human Tuft Cells	16
Cellular Crosstalk Promotes Hepatic Progenitor Cell Proliferation and Stellate Cell Activation in 3D Co-culture	16
Interferon Signaling Alters Epithelial Function in Eosinophilic Esophagitis	15
Unraveling the Oncogenic Characteristics of the Cytolinker, Plectin, in Esophageal Squamous Cell Carcinoma	15
Cover	15
Elevated Bile Acids Induce Circadian Rhythm Sleep Disorders in Chronic Liver Diseases	15
Correction	15
Beyond Regulation of Acid Secretion: A Novel Role for Histamine in Gastric Macrophage Differentiation and Function	15
All Good Things Come to an End: 5 Years at the Helm of CMGH	15
Rapid Research, High Impact: CMGH’s Short-Form Initiative	15
Osr1 Is a Critical Regulator of Macrophage Polarization in NASH Progression	15
PFKFB4 Is a Metabolic Driver of HCC Progression and Chemoresistance Through ROS Mitigation	14
HBV X Protein Induces Degradation of UBXN7, a Novel Negative Regulator of NF-κB Signaling, to Promote HBV Replication	14
Inhibition of Pyruvate Dehydrogenase Kinase 4 in CD4+ T Cells Ameliorates Intestinal Inflammation	14
Etomidate Improves Antitumor Immunity by Suppressing PD-L1 Expression in Hepatocellular Carcinoma Cells	14
Fueling HCC Dynamics: Interplay Between Tumor Microenvironment and Tumor Initiating Cells	14
Oxaliplatin-Resistant Hepatocellular Carcinoma Drives Immune Evasion Through PD-L1 Up-Regulation and PMN-Singular Recruitment	14
Pioneer Factor Foxa2 Mediates Chromatin Conformation Changes for Activation of Bile Acid Targets of FXR	14
Can Psyllium Alleviate Colitis?	14
Cellular Interactions and Crosstalk Facilitating Biliary Fibrosis in Cholestasis	14
Editorial Board	13
Novel Fat Taste Receptor Agonists Curtail Progressive Weight Gain in Obese Male Mice	13
Blautia coccoides Alleviates Acute Pancreatitis via Bile Salt Hydrolase-mediated Deoxycholic Acid Production and Farnesoid X Receptor Signaling	13
Signals From Within: The Microbial Tuner of Gut–Brain Interactions	13
Ubiquitination of Rhomboid 5 Homolog 2 by Constitutive Photomorphogenic 1 Alleviates Hepatic Ischemia-reperfusion Injury by Regulating the Transforming Growth Factor-β Activating Kinase 1-C-Jun N-term	13
Improving Gastric Motility in Aging Through EZH2 Inhibition and Preservation of Interstitial Cells of Cajal	13
Guiding Principles: Reporting Elements for Gastrointestinal Organoid Research	13
The STING That Tames Pro-inflammatory T-cells	13
Surgery for Crohn’s Disease Is Associated With a Dysbiotic Microbiome and Metabolome: Results From Two Prospective Cohorts	13
A Shared Framework for Gastrointestinal Organoid Research: It’s Time	13
Editorial Board	13
In Vivo Determinants of Hepatitis C Virus Adaptation and Escape From Neutralizing Antibody AR5A	12
GPR68, A Proton-sensing GPCR, Mediates Acid-induced Visceral Nociception	12
Mrgprb2-dependent Mast Cell Activation Plays a Crucial Role in Acute Colitis	12
D-amino Acids Ameliorate Experimental Colitis and Cholangitis by Inhibiting Growth of Proteobacteria: Potential Therapeutic Role in Inflammatory Bowel Disease	12
Differential MYC Phosphorylation Drives the Divergent Cholangiocyte Response to Stress	12

BRP39 Regulates Neutrophil Recruitment in NLRP3 Inflammasome-Induced Liver Inflammation	12
A Dual Role of HGF-ERK Signaling in IL6/HGF-induced Hepatocyte Proliferation	12
Kupffer Cell–Derived Exosomal S100A8/A9 Promotes Inflammasome–Dependent Pyroptotic Lung Injury in Acute Pancreatitis	12
The Alpha-Lipoic Acid Improves Glucose Metabolism and Hyperinsulinemia in Acute Intermittent Porphyria: A Nutritional Concept for the Management of Rare Disorders	12
A Tuft Cell-Dependent Pathway Linking Intestinal and Cognitive Health	12
Alterations in Cytoskeleton and Mitochondria in the Development and Reversal of Steatosis in Human Hepatocytes	12
Hepatic Ketogenesis Regulates Lipid Homeostasis via ACSL1-mediated Fatty Acid Partitioning	12
Intermittent Fasting: A Path to Reducing Obesity-Driven Mitochondrial and Gut Barrier Dysfunction to Improve Gut–Brain Axis	12
Storage Wars: Adipose-liver Crosstalk as a Determinant of Liver Injury	12
Glial Connexin-43 Is a Pathogenic Mechanism Promoting Gut Inflammation in Postoperative Ileus Induced by Gut Surgical Manipulation With Potential Relevance to Humans	11
Assessing Long-Term Liver Safety of Statins and PCSK9 Inhibitors Using Human Genetics	11
Disturbance of Oxylipin Metabolism Mediated by Autophagy of Mesenteric Adipocytes Orchestrates Gut Inflammation in Crohn’s Disease	11
HNF4α Acts as Upstream Functional Regulator of Intestinal Wnt3 and Paneth Cell Fate	11
Innate Immune Regulation: ABHD17 Is Calling NOD2 Back From Duty	11
Human Placental Extract Enhances Neonatal Intestinal Epithelial Reparative Capacity in Porcine Models	11
A Reflux Linked GATA Factor Fulcrum Dictates Lineage Commitment Through GPRC5B During the Esophageal Dysplastic Transition	11
Intestinal Stearoyl-CoA Desaturase-1 Regulates Energy Balance via Alterations in Bile Acid Homeostasis	11
Protection or Vulnerability? The Context-Dependent Memory of Intestinal Inflammation	11
Rethinking Fibrosis Regression in Alcohol-associated Liver Disease Through C/EBPβ Inhibition	11
Myeloid Cell Adhesion Molecule 1 (CADM1) Promotes Proinflammatory Signaling in Human Inflammatory Bowel Diseases	11
GPAT1 Deficiency in Mice Modulates NASH Progression in a Model-Dependent Manner	11
Platelets in Alcohol-Associated Liver Disease: Interaction With Neutrophils	11
Stromal Cell Regulation of Intestinal Inflammatory Fibrosis	11
Phosphocreatine Rescues Intestinal Epithelial Metabolic Dysfunction Related to Creatine Kinase Loss and Is Protective in Murine Colitis	11
NFATc1 Is a Central Mediator of EGFR-Induced ARID1A Chromatin Dissociation During Acinar Cell Reprogramming	11
Genome-wide CRISPR Screening Identifies NFκB and c-MET as Druggable Targets to Sensitize Lenvatinib Treatment in Hepatocellular Carcinoma	10
CREB Drives Acinar to Ductal Cells Reprogramming and Promotes Pancreatic Cancer Progression in Preclinical Models of Alcoholic Pancreatitis	10
Long Noncoding RNA uc173 is a Novel Regulator of Mitochondrial Metabolism Driving Intestinal Mucosal Growth	10
Reflux, Reprogramming, and Progenitor Fate: Reframing the Origins of Esophageal Dysplasia	10
TOC	10
Helicobacter pylori-Induced Inflammatory Cancer Transformation Microenvironment Drives Gastric Carcinogenesis	10
The Ties That Bind: Enteric Glia Link T Cells to Plexitis in Crohn’s	10
Paneth Cells: Dispensable yet Irreplaceable for the Intestinal Stem Cell Niche	10
IGF2BP1/IMP1 Deletion Enhances a Facultative Stem Cell State via Regulation of MAP1LC3B	10
The P2X7 Receptor Promotes Intestinal Fibrosis by Modulating the Gut Microbiota and the Inflammasome	10
Imperatorin Alleviates Intestinal Fibrosis by Suppressing AIM2-mediated GSDMD Pyroptosis in Macrophages	10
Colorectal 15-Lipoxygenase-1 as a Host Factor Determining the Effects of Eicosapentaenoic Acid and Docosahexaenoic Acid on Colorectal Tumorigenesis in Mice	10
Shc Is Implicated in Calreticulin-Mediated Sterile Inflammation in Alcoholic Hepatitis	10
Introducing Article Numbering to Cellular and Molecular Gastroenterology and Hepatology	10
Hepatitis B Virus Utilizes a Retrograde Trafficking Route via the Trans-Golgi Network to Avoid Lysosomal Degradation	10
Deriving Human Intestinal Organoids with Functional Tissue-Resident Macrophages All From Pluripotent Stem Cells	10
Sphingosine Kinase 1 – A Therapeutic Opportunity for Alleviating Liver Fibrosis?	10
Dysregulation of the Environmental Sensor Aryl Hydrocarbon Receptor Affects Differentiation of Human Colon Organoids	10
Hepatitis B Virus-KMT2B Integration Drives Hepatic Oncogenic Processes in a Human Gene-edited Induced Pluripotent Stem Cells-derived Model	10