Regenerative Therapy

Article	Citations
Effects of plasma rich in growth factors on wound healing in patients with venous ulcers	124
Estradiol enhanced neuronal plasticity and ameliorated astrogliosis in human iPSC-derived neural models	114
CD73-positive pediatric urethral mesenchymal stem-like cell-derived small extracellular vesicles stimulate angiogenesis	69
Circ_ROBO2/miR-186-5p/TRIM14 axis regulates oxidized low-density lipoprotein-induced cardiac microvascular endothelial cell injury	66
Bridging potential of Taurine-loading PCL conduits transplanted with hEnSCs on resected sciatic nerves	40
Xenotransplantation of cryopreserved human clumps of mesenchymal stem cells/extracellular matrix complexes pretreated with IFN-γ induces rat calvarial bone regeneration	40
Baseline magnetic resonance imaging findings associated with short-term clinical outcomes after intraarticular administration of autologous adipose-derived stem cells for knee osteoarthritis	38
Chronic prosthesis-related residual limb ulcer treated with autologous micro-fragmented adipose tissue	38
Selective effects of collagen-derived peptides Pro-Hyp and Hyp-Gly on the proliferation and differentiation of SSEA3-positive human dental pulp stem cells	34
Stress and motivation of cell processing operators: A pilot study of an online questionnaire survey	34
Diverting the food-freezing technology improves the cryopreservation efficiency of induced pluripotent stem cells and derived neurospheres	31
Study on promoting the regeneration of grafted fat by cell-assisted lipotransfer	30
CircRNA PVT1 modulated cell migration and invasion through Epithelial-Mesenchymal Transition (EMT) mediation in gastric cancer through miR-423-5p/Smad3 pathway	29
Positive effect of Periostin on repair of Isopreternol induced ischemic damaged cardiomyocyte: an in vitro model	29
Research status of facial nerve repair	29
The generation of islet-like insulin-producing cells from Wharton's jelly-derived mesenchymal stem cells on the PES/fish gelatin scaffold	29
Efficient cell transplantation combining injectable hydrogels with control release of growth factors	28
The potential of Spirulina maxima extract-treated conditioned medium from adipose-derived mesenchymal stem cells for hair growth promoting effect on human dermal papilla cells	27
Return to the original sport at only 3 months after an Achilles tendon rupture by a combination of intra-tissue injection of freeze-dried platelet-derived factor concentrate and excessively early reha	27
Prospects and challenges in NMDAR signaling in spinal cord injury recovery and neural circuit remodeling	24
Effect of silk fibroin scaffold loaded with 17-β estradiol on the proliferation and differentiation of BMSCs	24
Comparative gastrointestinal organoid models across species: A Zoobiquity approach for precision medicine	24
Optimal dose of bone marrow mesenchymal stem cell transplantation for experimental ulcerative colitis	23
Intrauterine injection of bioengineered hydrogel loaded exosomes derived from HUCM stem cells and spermidine prominently augments the pregnancy rate in thin endometrium rats	23
Modeling human congenital disorders with neural crest developmental defects using patient-derived induced pluripotent stem cells	22

Adipogenesis of bioabsorbable implants under irradiation in a rodent model	22
Clinical challenges of short bowel syndrome and the path forward for organoid-based regenerative medicine	21
In vitro effects of conditioned medium from bioreactor cultured human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) on skin-derived cell lines	21
Xenogeneic mesenchymal stem cell biocurative improves skin wounds healing in diabetic mice by increasing mast cells and the regenerative profile	21
A new clinical classification and reconstructive strategy for post-sternotomy surgical site infection	21
Tanshinone IIA protects motor neuron-like NSC-34 cells against lipopolysaccharide-induced cell injury by the regulation of the lncRNA TCTN2/miR-125a-5p/DUSP1 axis	20
Regenerative medicine strategies for hair growth and regeneration: A narrative review of literature	20
Decreasing electricity costs of clean room for cell products during non-operation	19
Characterization of dynamical changes in vital signs during allogeneic human umbilical cord-derived mesenchymal stem cells infusion	19
Efficacy of chitinase-3-like protein 1 as an in vivo bone formation predictable marker of maxillary/mandibular bone marrow stromal cells	19
Intra-articular administration of autologous adipose-derived stem cells in hip osteoarthritis: Longitudinal treatment trajectories and prognostic factors	19
Downregulation of hsa_circ_0000885 suppressed osteosarcoma metastasis and progression via regulating E2F3 expression and sponging miR-16-5p	19
Alkali-extracted proteins from the tooth dentin matrix as a mixture of bioactive molecules for cartilage repair and regeneration	19
Phenytoin regulates osteogenic differentiation of human bone marrow stem cells by PI3K/Akt pathway	18
Electro-spun piezoelectric PLLA smart composites as a scaffold on bone fracture: A review	18
Human umbilical cord mesenchymal stem cells protect MC3T3-E1 osteoblasts from dexamethasone-induced apoptosis via induction of the Nrf2-ARE signaling pathway	18
Systematic review: Impact of stem cells-based therapy, and platelet-rich plasma in hair loss and telogen effluvium related to COVID-19	18
Knee meniscus regeneration using autogenous injection of uncultured adipose tissue-derived regenerative cells	17
A case series of platelet rich plasma in chronic venous ulcers	16
Harvesting methods of umbilical cord-derived mesenchymal stem cells from culture modulate cell properties and functions	16
Interposition grafting of collagen-gelatin sponge impregnated with basic fibroblast growth factor in primary palatoplasty	16
Self-assembling peptide nanofibers and nanoceramics in a model of alveolar bone repair: Insights from in vivo experiments and clinical trial	16
A novel cell source for therapy of knee osteoarthritis using atelocollagen microsphere-adhered adipose-derived stem cells: Impact of synovial fluid exposure on cell activity	16
DDIT4 participates in high glucose-induced fibroblast-like synoviocytes overactivation and cartilage injury by regulating glycolysis	16
Therapeutic potential of exosomes derived from human endometrial mesenchymal stem cells for heart tissue regeneration after myocardial infarction	15
Effects of fresh bone marrow mononuclear cell therapy in rat model of retinopathy of prematurity	15
Opinions on research involving human embryo models by researchers and the general public	15
Development of hydroxyapatite-coated nonwovens for efficient isolation of somatic stem cells from adipose tissues	15
Bioactive and biodegradable hydrogel based on the dermal matrix loaded with microspheres containing vascular endothelial growth factor (VEGF) and interleukin (IL)-10 accelerated the healing of diabeti	15
Editorial Board	15
Cbx7 promotes the generation of induced pluripotent stem cells	15
Neural regeneration ability of Polypyrrole-Collagen-Quercetin composite in the spinal cord injury	14
Clinical trial of autologous adipose tissue-derived regenerative (stem) cells therapy for exploration of its safety and efficacy	14
An efficient feeder-free and chemically-defined expansion strategy for highly purified natural killer cells derived from human cord blood	14
Unveiling the superior function of RADA in bone regeneration compared to KSL as two critical cores within self-assembling peptide nanofibers: Insights from in vitro and in vivo studies	14
Fabrication of gelatine/fucoidan nanogel-coated silver nanoparticles for the treatment of wound healing therapy and nursing care	14
In vitro and functional investigation reveals the curative effect of thymoquinone from black cumin-loaded chitosan nanoparticles on streptozotocin induced paediatric diabetes	13
Technology using simulated microgravity	13
Recommendations for the safe implementation of intravenous administration of mesenchymal stromal cells	13
Transplantation of chemically-induced liver progenitor cells ameliorates hepatic fibrosis in mice with diet-induced nonalcoholic steatohepatitis	13
Editorial Board	13
Reawakening GDNF's regenerative past in mice and humans	12
Standardizing decellularization protocols for optimized uterine tissue bioengineering	12
A new soft tissue constructed with chitosan for wound dressings-incorporating nanoparticles for medical and nursing therapeutic efficacy	12
Human corneal organoid has a limbal function that supplies epithelium to the cornea with limbal deficiency	12
Enriched human embryonic stem cells-derived CD133+, CD24+ renal progenitors engraft and restore function in a gentamicin-induced kidney injury in mice	12
Effects of basic fibroblast growth factor on cartilage to bone: Time-course histological analysis of in vivo cartilage formation from polydactyly-derived chondrocytes	12
Actin mesh in Re-epithelialization during skin regeneration in adult newt (Cynops pyrrhogaster)	12
Research of in vivo reprogramming toward clinical applications in regenerative medicine: A concise review	12
Umbilical cord mesenchymal stem cells: A novel approach to intervention of ovarian ageing	11

Exosomal U2AF2 derived from human bone marrow mesenchymal stem cells attenuates the intervertebral disc degeneration through circ_0036763/miR-583/ACAN axis	11
Bibliometric analysis of hydrogels in bone regeneration: Research trends and future perspectives	11
Phenotypic features of genetically modified DMD-XKOXWT pigs	11
Promotion of hMDSC differentiation by combined action of scaffold material and TGF-β superfamily growth factors	11
Pluripotent stem cell-derived retinal organoid/cells for retinal regeneration therapies: A review	11
Modeling of intramembranous ossification using human pluripotent stem cell-derived paraxial mesoderm derivatives	11
Evaluation of decellularized caprine small intestine submucosa encapsulated with nano-formulations of cerium oxide and curcumin in the management of burn wound	11
Transplantation of human umbilical cord blood mononuclear cells promotes functional endometrium reconstruction via downregulating EMT in damaged endometrium	11
miR-30a inhibits the osteogenic differentiation of the tibia-derived MSCs in congenital pseudarthrosis via targeting HOXD8	11
Viral-based gene therapy clinical trials for immune deficiencies and blood disorders from 2013 until 2023 - an overview	11
Superior stemness of a rapidly growing subgroup of isolated human auricular chondrocytes and the potential for use in cartilage regenerative therapy	11
Adipose-derived mesenchymal stem cells preserve cardiac function via ANT-1 in dilated cardiomyopathy hamster model	11
Subcutaneous implantation of tooth germ stem cells over the masseter muscle in mice: An in vivo pilot study	11
Comparisons of the effects of silk elastin and collagen sponges on wound healing in murine models	10
Human bone marrow mesenchymal stem cell-derived exosomes containing microRNA-425 promote migration, invasion and lung metastasis by down-regulating CPEB1	10
Bulk RNA sequencing reveals the comprehensive genetic characteristics of human cord blood-derived natural killer cells	10
Berberine ameliorates endothelial progenitor cell function and wound healing in vitro and in vivo via the miR-21-3p/RRAGB axis for venous leg ulcers	10
Human placental extract improves liver cirrhosis in mice with regulation of macrophages and senescent cells	10
MiR-590-3p affects the function of adipose-derived stem cells (ADSCs) on the survival of skin flaps by targeting VEGFA	10
A novel role of CD73-IFNγ signalling axis in human mesenchymal stromal cell mediated inflammatory macrophage suppression	10
Fenugreek seed extract combined with acellular nerve allografts promotes peripheral nerve regeneration and neovascularization in sciatic nerve defects	10
Exosomes derived stem cells as a modern therapeutic approach for skin rejuvenation and hair regrowth	10
Current status of ischemic stroke treatment: From thrombolysis to potential regenerative medicine	10
Editorial Board	9
Exosome-based approaches in cancer along with unlocking new insights into regeneration of cancer-prone tissues	9
Preface to the special issue of “Regenerative therapy”: “Future of regenerative medicine viewed by young scientists”	9
Canine adipose-derived mesenchymal stromal cells inhibit the growth of canine hematologic malignancy cell lines	9
Transplantation of acellularized dermis matrix (ADM) plus fully covered metal stent to prevent stricture after circumferential endoscopic submucosal dissection of early esophageal cancer (with video)	9
Gliko BMSC: A potential strategy of treatment for renal fibrosis	9
Stable preparation of in vivo transplantable periodontal ligament-derived mesenchymal stem cell sheets in thermoresponsive culture dishes with tunable cell detachability	9
Relationship between oxygen partial pressure and inhibition of cell aggregation of human adipose tissue-derived mesenchymal stem cells stored in cell preservation solutions	9
Optimal frequency of platelet-rich plasma injections for managing osteoarthritis: A longitudinal study	9
Dynamic tracking of human umbilical cord mesenchymal stem cells (hUC-MSCs) following intravenous administration in mice model	9
Method standardization of secretome production, collection, and characterization: New insights and challenges	9
Personalized tissue-engineered arteries as vascular graft transplants: A safety study in sheep	9
Prospect of 3D bioprinting over cardiac cell therapy and conventional tissue engineering in the treatment of COVID-19 patients with myocardial injury	9
The phenotypic characterization of mouse floxed Fam20b chondrocytes, a novel articular cartilage-derived cell line with differentiation potential	9
Modified human skin cell isolation protocol and its influence on keratinocyte and melanocyte culture	9
Mesenchymal stem cell-derived extracellular vesicles/exosome: A promising therapeutic strategy for intracerebral hemorrhage	8
Effect of a FOXO1 inhibitor on trophoblast differentiation from human pluripotent stem cells and ERV-associated gene expression	8
Editorial Board	8
Non-apoptotic regulated cell death in Fuchs endothelial corneal dystrophy	8
Platelet-rich plasma therapy for knee osteoarthritis: Insights from real-world clinical data in Japan	8
Retraction notice to “Preclinical assessment of transplantable human nasal mucosal epithelial cell sheets” [Regenerative Therapy 18 (2021) 59–65]	8
Association with cationized gelatin nanospheres enhances cell internalization of mitochondria efficiency	8
Potential therapeutic effects and nano-based delivery systems of mesenchymal stem cells and their isolated exosomes to alleviate acute respiratory distress syndrome caused by COVID-19	8
Mineralized collagen scaffold bone graft accelerate the osteogenic process of HASCs in proper concentration	8
Single-cell RNA sequencing unravels heterogeneity of skeletal progenitors and cell–cell interactions underlying the bone repair process	8
A comparative analysis of attitudes toward stem cell research and regenerative medicine between six countries – A pilot study	8
Clinical efficacy of invimestrocel for acute respiratory distress syndrome caused by pneumonia: Comparison with historical data using propensity score analysis	8
Long term observation of de novo adipogenesis using novel bioabsorbable implants with larger size in a porcine model	8
Generation of functional liver sinusoidal endothelial-like cells from human bone marrow-derived mesenchymal stem cells	8
Mesenchymal stem cell therapy in ischemic stroke trials. A systematic review	8
Reconstitution and post-thaw storage of cryopreserved human mesenchymal stromal cells: Pitfalls and optimizations for clinically compatible formulants	8
Scanning electron microscopy analysis of synovial and adipose mesenchymal stem cells adhering to cartilage	8
Simultaneous binding of bFGF to both FGFR and integrin maintains properties of primed human induced pluripotent stem cells	8
MiRNA-218 inhibits cell proliferation, migration and invasion by targeting Runt-related transcription factor 2 (Runx2) in human osteosarcoma cells	8
Investigating the effect of mesenchymal stem cells on the rate of clinical and pathological improvement of asthmatic lung in mouse model	8
Spatial heterogeneity analysis of seeding of human induced pluripotent stem cells for neuroectodermal differentiation	8
Autologous concentrated growth factor mediated accelerated bone healing in root-end microsurgery: A multicenter randomized clinical trial	8
Dendrobium officinale polysaccharide promotes angiogenesis as well as follicle regeneration and hair growth through activation of the WNT signaling pathway	7
Iron-Quercetin complex enhances mesenchymal stem cell-mediated HGF secretion and c-Met activation to ameliorate acute kidney injury through the prevention of tubular cell apoptosis	7
Biodistribution studies for cell therapy products: Current status and issues	7
Safety and efficacy of bone marrow derived-mesenchymal stem cells transplantation in patients with amyotrophic lateral sclerosis	7
Interceed combined with bone marrow mesenchymal stem cells improves endometrial receptivity of intrauterine adhesion	7
Investigating the attenuating effects of metformin-loaded selenium nanoparticles coupled with Myrtus communis L. flower extract on CaOx deposition in male Sprague Dawley rat kidneys via regulating MAP	7
Preventing MSC aging and enhancing immunomodulation: Novel strategies for cell-based therapies	7
Fabrication of Biologically Inspired Electrospun Collagen/Silk fibroin/bioactive glass composited nanofibrous scaffold to accelerate the treatment efficiency of bone repair	7
Design and development of pH-responsive levofloxacin-loaded metal-organic framework for the promising treatment of pediatric abdominal wound repair	7
Current regenerative medicine-based approaches for skin regeneration: A review of literature and a report on clinical applications in Japan	7
Long-term culture of rat hepatocytes using human amniotic membrane as a culture substrate	7
Prognostic factors affecting periodontal regenerative therapy using recombinant human fibroblast growth factor-2: A 3-year cohort study	7
Enhancing chondrogenic potential via mesenchymal stem cell sheet multilayering	7
Laminin-221-derived recombinant fragment facilitates isolation of cultured skeletal myoblasts	7
The superficial branch of the radial nerve and sensory disturbance in the radial forearm flap donor-site	7
A single allele of the hsa-miR-302/367 cluster maintains human pluripotent stem cells	7
Nisin-preconditioned mesenchymal stem cells combatting nosocomial Pseudomonas infections	7
Role of cell-based therapies in digestive disorders: Obstacles and opportunities	7
The NFATC2/Nrf2 cascade regulates spinal cord ischemia-reperfusion injury by controlling inflammation, apoptosis and oxidative stress	7
A review and update for registered clinical studies of stem cells for non-tumorous and non-hematological diseases	7

New insight of immuno-engineering in osteoimmunomodulation for bone regeneration	7
Biological function and application of melanocytes induced and transformed by mouse bone marrow mesenchymal stem cells	7
Evaluating the quality of studies reporting on clinical applications of stromal vascular fraction: A systematic review and proposed reporting guidelines (CLINIC-STRA-SVF)	7
Establishment of reproducible method for production of cultured epidermal sheets with controlled melanocyte density	7
Mesenchymal stem cells: Guardians of women's health	7
Repair of ovine peripheral nerve injuries with xenogeneic human acellular sciatic nerves prerecellularized with allogeneic Schwann-like cells—an innovative and promising approach	7
Applications of blood plasma derivatives for cutaneous wound healing: A mini-review of clinical studies	7